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Paeoniflorin
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the production of testosterone and promotes the activity of aromatase-the enzyme that converts testosterone into estrogen. Uses: Antiandrogenic properties. Alternative Names: 9[(Benzoyioxy)methyl]-1-(b-D-glucopyranosyloxy)-4,8-epoxy-6-methyl-7-oxaticyclo[4,3,0,0]nonane. Grades: >98%. CAS No. 23180-57-6. Molecular formula: C23H28O11. Mole weight: 480.46.
Palbociclib Impurity 026
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C28H37N7O2. Mole weight: 503.64.
Paldimycin
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Alternative Names: Antibiotic 273 A1; (5S)-5-[5-[3-[(2R)-2-acetamido-2-carboxyethyl]sulfanyl-2-[[(2R)-2-acetamido-2-carboxyethyl]sulfanylcarbothioylamino]butanoyl]oxy-6-(acetyloxymethyl)-3-hydroxy-4-[5-hydroxy-4-methoxy-6-methyl-5-[(1S)-1-(2-methylpropanoyloxy)ethyl]oxan-2-yl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; (5S)-5-[5-[3-[(2R)-2-acetamido-2-carboxyethyl]sulfanyl-2-[[(2R)-2-acetamido-2-carboxyethyl]sulfanylcarbothioylamino]butanoyl]oxy-6-(acetyloxymethyl)-3-hydroxy-4-[5-hydroxy-4-methoxy-6-methyl-5-[(1S)-1-[(2S)-2-methylbutanoyl]oxyethyl]oxan-2-yl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid. CAS No. 102426-96-0. Molecular formula: C87H126N8O46S6. Mole weight: 2212.34.
Paldimycin A
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Alternative Names: Antibiotic 273 A1-alpha; L-Cysteine, N-acetyl-, [2-[[2-(acetylamino)-2-carboxyethyl]thio]-1-carboxypropyl]carbamodithioate(ester), 4'-ester with 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[1-(2-methyl-1-oxobutoxy)ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4''-C-((2S)-2-methylbutyrate), S-ester with N-acetyl-L-cysteine. CAS No. 101411-70-5. Molecular formula: C44H64N4O23S3. Mole weight: 1113.18.
Paldimycin B
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Alternative Names: Antibiotic 273 A1-Beta; 2-Amino-5-(3-O-(2,6-dideoxy-4-C-((1S)-1-hydroxyethyl)-3-O-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid, 4'-(3-(((2R)-2-acetamido-2-carboxyethyl)thio)-2-((dithiocarboxy)amino)butyrate), 6'-acetate, 4'-C-isobutyrate, S-ester with N-acetyl-L-cysteine; L-Cysteine, N-acetyl-, (2-((2-(acetylamino)-2-carboxyethyl)thio)-1-carboxypropyl)carbamodithioate (ester), 1'-4'-ester with 5-(6-O-acetyl-3-O-(2,6-dideoxy-3-O-methyl-4-C-(1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-1-cyclohexene-1-carboxylic acid. CAS No. 101411-71-6. Molecular formula: C43H62N4O23S3. Mole weight: 1099.16.
Palitantin
It is produced by the strain of Pen. palitans. It is an antibiotic with antifungal and antiprotozoal properties. Alternative Names: NSC-246119; Cyclohexanone, 3-(1E,3E)-1,3-heptadien-1-yl-5,6-dihydroxy-2-(hydroxymethyl)-, (2R,3S,5R,6R)-; rel-(2R,3S,5R,6R)-3-(1E,3E)-1,3-Heptadien-1-yl-5,6-dihydroxy-2-(hydroxymethyl)cyclohexanone; (±)-Palitantin; [2α,3β(1E,3E),5α,6α]-3-(1,3-Heptadienyl)-5,6-dihydroxy-2-(hydroxymethyl)-cyclohexanone. Grades: ≥95%. CAS No. 15265-28-8. Molecular formula: C14H22O4. Mole weight: 254.32.
p-Allylphenol
A useful research chemical. Alternative Names: 4-(2-propenyl)-pheno; 4-(Prop-2-enyl)-phenol; Chavicol; gamma-(p-Hydroxyphenyl)-alpha-propylene; p-Allylphenol; p-Chavicol; Phenol, 4-(2-propenyl)-; Phenol, p-allyl-. Grades: 95%. CAS No. 501-92-8. Molecular formula: C9H10O. Mole weight: 134.18.
Palmatine hydrochloride
Palmatine hydrochloride (Palmatine chloride) is a hydrochloride salt of palmatine, a protoberberine alkaloid that has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. It acts as an inhibitor of dopamine generation which reduces Ca2+ levels. Alternative Names: Palmatine chloride; 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride. Grades: ≥98% (HPLC). CAS No. 10605-02-4. Molecular formula: C21H22ClNO4. Mole weight: 387.86.
Palmitoylcoprogen
Palmitoylcoprogen. Alternative Names: Iron, [(3E)-5-[(hydroxy-κO)[3-[(2S,5S)-5-[3-[(hydroxy-κO)[(2E)-5-hydroxy-3-methyl-1-(oxo-κO)-2-penten-1-yl]amino]propyl]-3,6-dioxo-2-piperazinyl]propyl]amino]-3-methyl-5-(oxo-κO)-3-penten-1-yl N5-(hydroxy-κO)-N5-[(2E)-5-hydroxy-3-methyl-1-(oxo-κO)-2-penten-1-yl]-N2-(1-oxohexadecyl)-L-ornithinato(3-)]-. CAS No. 1807362-49-7. Molecular formula: C49H81FeN6O13. Mole weight: 1018.06.
Paludosic acid. Alternative Names: o-Anisic acid, 4-hydroxy-6-propyl-, 3-ester with 2,3,4-trihydroxy-6-pentylbenzoic acid (8CI); 2,4-Dihydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-6-pentylbenzoic acid; 4-O-Demethylmerochloropheic acid; Benzoic acid, 2,4-dihydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-6-pentyl-. CAS No. 19833-81-9. Molecular formula: C23H28O8. Mole weight: 432.46.
Panamine diperchlorate
It comes from the seeds of the ormosia species. Alternative Names: (1S,5R,5a1R,8aS,10S,10aR,15aR)-tetradecahydro-1H,6H,9H,15H-5a,14a,17-triaza-1,5:10,15a-dimethanodibenzo[b,fg]octalene diperchloric acid; (6ξ,18S,20R)-12,20-Cycloormosanine perchlorate (1:2); 15H-1,5-Imino-10,15a-methano-1H,6H,9H-5a,14a-diazadibenz[b,fg]octalene, tetradecahydro-, (1S,5R,8aS,10S,15aR,15bR)-, perchlorate (1:2). CAS No. 6011-96-7. Molecular formula: C20H33N3.2ClHO4. Mole weight: 516.41.
Panaxcerol C
Monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) are the two nonionic lipid constituents of the thylakoid membrane of higher plant chloroplasts. MGDG and DGDG are present in the membrane at 56% and 29%, respectively, of the total lipid content. DGDG is a bilayer-forming lipid, while MGDG alone will only form hexagonal-II structures. Alternative Names: Monogalactosyldiacylglycerol (Plant); 1,2-diacyl-3-O-β-D-galactosyl-sn-glycerol; MGDG; 1-18:3-2-18:3-Monogalactosyldiacylglycerol; 18:3-18:3-MGDG; 1,2-Di-O-alpha-linolenoyl-3-O-beta-galactopyranosyl-sn-glycerol; 1,2-(9Z,12Z,15Z-octadecatrienoyl)-3-O-beta-D-galactosyl-sn-glycerol; (9Z,9'Z,12Z,12'Z,15Z,15'Z)-(S)-3-(((2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propane-1,2-diyl bis(octadeca-9,12,15-trienoate); β-D-Galactopyranoside, (2S)-2,3-bis[[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]oxy]propyl. Grades: >95%. CAS No. 63180-02-9. Molecular formula: C45H74O10. Mole weight: 775.06.
Panclicin A
It is produced by the strain of Str. sp. NR 0619. It's an enzyme inhibitor. Alternative Names: L-Alanine, N-formyl-, (1S)-1-[[(2S,3S)-3-(8-methylnonyl)-4-oxo-2-oxetanyl]methyl]octyl ester; L-Alanine, N-formyl-, 1-[[3-(8-methylnonyl)-4-oxo-2-oxetanyl]methyl]octyl ester, [2S-[2a[R*(R*)],3b]]-; (-)-Panclicin A. CAS No. 160669-37-4. Molecular formula: C26H47NO5. Mole weight: 453.65.
Panclicin B
It is produced by the strain of Str. sp. NR 0619. It's an enzyme inhibitor. Alternative Names: L-Alanine, N-formyl-,(1S)-1-[[(2S,3S)-3-decyl-4-oxo-2-oxetanyl]methyl]octyl ester; L-Alanine, N-formyl-, 1-[(3-decyl-4-oxo-2-oxetanyl)methyl]octyl ester, [2S-[2a[R*(R*)],3b]]-; (-)-Panclicin B. CAS No. 160700-42-5. Molecular formula: C26H47NO5. Mole weight: 453.65.
Panclicin C
It is produced by the strain of Str. sp. NR 0619. It's an enzyme inhibitor. Alternative Names: Glycine, N-formyl-, (1S)-1-[[(2S,3S)-3-(8-methylnonyl)-4-oxo-2-oxetanyl]methyl]octyl ester; Glycine, N-formyl-, 1-[[3-(8-methylnonyl)-4-oxo-2-oxetanyl]methyl]octyl ester, [2S-[2a(R*),3b]]-; (-)-Panclicin C. CAS No. 160669-43-2. Molecular formula: C25H45NO5. Mole weight: 439.63.
Panclicin D
It is produced by the strain of Str. sp. NR 0619. It's an enzyme inhibitor. Alternative Names: (-)-Panclicin D. CAS No. 160669-44-3. Molecular formula: C25H45NO5. Mole weight: 439.63.
Panclicin E
It is produced by the strain of Str. sp. NR 0619. It's an enzyme inhibitor. Alternative Names: Glycine, N-formyl-, (1S)-1-[[(2S,3S)-3-dodecyl-4-oxo-2-oxetanyl]methyl]octyl ester; Glycine, N-formyl-, 1-[(3-dodecyl-4-oxo-2-oxetanyl)methyl]octyl ester, [2S-[2a(R*),3b]]-; (-)-Panclicin E. CAS No. 160669-45-4. Molecular formula: C27H49NO5. Mole weight: 467.68.
Pannaric acid
Pannaric acid. Alternative Names: 3,9-dihydroxy-1,7-dimethyldibenzo[b,d]furan-2,6-dicarboxylic acid; 2,6-Dibenzofurandicarboxylic acid, 3,9-dihydroxy-1,7-dimethyl-; Pannarsaeure. CAS No. 479-46-9. Molecular formula: C16H12O7. Mole weight: 316.26.
Pannaric acid 6-methyl ester
Pannaric acid 6-methyl ester is a metabolite from the lichen leproloma diffusum. Molecular formula: C17H14O7. Mole weight: 330.29.
Pannarin
It is a lichen metabolite isolated from several Psoroma species. Alternative Names: 8-chloro-9-hydroxy-3-methoxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; Pannarine; NSC 646008; 11H-Dibenzo(b,e)(1,4)dioxepin-4-carboxaldehyde, 2-chloro-3-hydroxy-8-methoxy-1,6,9-trimethyl-11-oxo-. CAS No. 55609-84-2. Molecular formula: C18H15ClO6. Mole weight: 362.76.
Panosialin A
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It can inhibit the influenza virus and has weak anti-microbial effect. Alternative Names: Panosialin I; 1,3-Benzenediol, 5-(13-methyltetradecyl)-, bis(hydrogen sulfate). Molecular formula: C21H36O8S2. Mole weight: 480.63.
Panosialin B
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, but it has weak anti-microbial effect. Alternative Names: 5-Pentadecylresorcinol 1,3-bissulfuric acid; Panosialin II; Panosialin-IA; Resorcinol, 5-pentadecyl-, disulfate (ester); 5-Pentadecyl-1,3-phenylenbis(hydrogensulfat). Molecular formula: C21H36O8S2. Mole weight: 480.63.
Panosialin C
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, but it has weak anti-microbial effect. Alternative Names: 5-(14-Methylpentadecyl)resorcinol 1,3-bissulfuric acid; Panosialin III. Molecular formula: C22H38O8S2. Mole weight: 494.66.
Panosialin D
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, but it has weak anti-microbial effect. Alternative Names: 5-(13-methylpentadecyl)-1,3-phenylene bis(hydrogen sulfate); 1,3-Benzenediol, 5-(13-methylpentadecyl)-, bis(hydrogen sulfate); Panosialin ?. Molecular formula: C22H38O8S2. Mole weight: 494.66.
Panosialin wA
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, it has weak anti-microbial effect. Molecular formula: C21H36O5S. Mole weight: 400.57.
Panosialin wB
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, it has weak anti-microbial effect. Molecular formula: C21H36O5S. Mole weight: 400.57.
Panosialin wC
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, it has weak anti-microbial effect. Molecular formula: C22H38O5S. Mole weight: 414.60.
Panosialin wD
It is produced by the strain of Str. sp OH-5186. It can inhibit α,β-glucosidase and mannose glycosidase. It does not inhibit the influenza virus, it has weak anti-microbial effect. Molecular formula: C22H38O5S. Mole weight: 414.60.
Papulacandin A
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Alternative Names: 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-(1-oxo-2,4-decadienyl)-β-D-galactopyranosyl]-α-D-glucopyranose3-(7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[(7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraenyl)oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-(2,4-decadienoate). CAS No. 61036-46-2. Molecular formula: C47H66O16. Mole weight: 887.02.
Papulacandin B
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. The mechanism of B is to inhibit the synthesis of glucan in yeast cell wall. Alternative Names: alpha-D-Glucopyranose, 1,16-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4,6-decatrienyl)-beta-D-galactopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-2,4,8,10-hexadecatetraenoate); β-D-Galactopyranoside, (1S,3'R,4'R,5'R,6'R)-3',4',5',6'-tetrahydro-3',5,7-trihydroxy-4'-[[(2E,4E,8E,10E)-7-hydroxy-8,14-dimethyl-1-oxo-2,4,8,10-hexadecatetraen-1-yl]oxy]-6'-(hydroxymethyl)spiro[isobenzofuran-1(3H),2'-[2H]pyran]-5'-yl,6-[(2E,4Z,6E)-8-hydroxy-2,4,6-decatrienoate]. CAS No. 61032-80-2. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin C
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Alternative Names: (1S,3'R,4'R,5'R,6'R)-3',5,7-trihydroxy-5'-({6-O-[(2E,4E,6E)-8-hydroxydeca-2,4,6-trienoyl]-beta-D-galactopyranosyl}oxy)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate; 1,1-O-(4,6-Dihydroxy-1,2-phenylenemethylene)-4-O-[6-O-[(2E,4E,6E)-1-oxo-8-hydroxy-2,4,6-decatrienyl]-beta-D-galactopyranosyl]-alpha-D-glucopyranose 3-[(2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate]. CAS No. 61036-48-4. Molecular formula: C47H64O17. Mole weight: 901.00.
Papulacandin D
It is produced by the strain of Papularia sphaerosperma. It has strong anti-yeast effect, but no effect on filiform fungi, bacteria and protozoa. It has no cross-resistance with polyene antibiotics, Conocandin and azole antifungal chemotherapy drugs, but has partial cross-resistance with Echinocandin B. Among the four components, Papulacandin C has the strongest activity and Papulacandin D has the weakest activity. Alternative Names: (+)-papulacandin D; (1S,3'R,4'S,5'R,6'R)-3',5,5',7-tetrahydroxy-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoate. CAS No. 61036-49-5. Molecular formula: C31H42O10. Mole weight: 574.66.
Papyracon ?
It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect. Alternative Names: Lachnumfuran A. Molecular formula: C14H18O4. Mole weight: 250.29.
Papyracon ?
It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect. Alternative Names: 6-O-Methylpapyracon B. Molecular formula: C15H22O5. Mole weight: 282.33.
Papyracon ?
It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect. Alternative Names: Lachnumlactone A. Molecular formula: C14H18O5. Mole weight: 266.29.
Papyracon D
It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect. Molecular formula: C14H18O5. Mole weight: 266.29.
Papyracon III
It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. Alternative Names: 6-O-Methylpapyracon C. Molecular formula: C15H22O5. Mole weight: 282.33.
Paraherquamide E
A member of the paraherquamide family which causes a potent non-toxic paralysis of nematode. It is a fungal metabolite originally isolated from Penicillium charlesii with anthelmintic and insecticidal activities. Alternative Names: Antibiotic VM 54159; VM 54159; 14-Deoxyparaherquamide A; (1'S,5'aS,7'R,8'aS,9'aR)-2',3',8'a,9'-tetrahydro-1',4,4,8',8',11'-hexamethyl-spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione. Grades: >99% by HPLC. CAS No. 125600-53-5. Molecular formula: C28H35N3O4. Mole weight: 477.60.
Parietinic acid
Parietinic acid. Alternative Names: Parietic acid; AGN-PC-00AILM. CAS No. 17636-18-9. Molecular formula: C16H10O7. Mole weight: 314.25.
Parimycin
It is produced by the strain of Streptomyces sp. B 8652. It has activity against gram-positive bacteria, negative bacteria and tumors, and no effect on fungal. It can inhibit tumor cells including GXF 251L, H640, LXFA 629L, MCF-7, MEXF 514L with IC70 of 0.9-6.7 μg/mL. Molecular formula: C22H20O7. Mole weight: 396.39.
Paromomycin II
It is produced by the strain of Str. rimosus forma paromomycinus NRRL 2455. It's an aminoglycoside antibiotic. It has activity against gram-positive, negative bacteria, mycobacterium and protozoa. It has good curative effect for amebic dysentery and a few bacillary dysentery. Alternative Names: Neomycin Sulfate EP Impurity F; Neomycin Impurity F; Framycetin sulfate EP Impurity F; Neomycin B sulfate EP Impurity F; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-D-streptamine; Neomycin F; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine; O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; Paromomycin II; Aminosidin II; Aminosidine II; Zygomycin A2. Grades: ≥95%. CAS No. 51795-47-2. Molecular formula: C23H45N5O14. Mole weight: 615.63.
Parthenolide
(-)-Parthenolide is a sesquiterpene lactone which occurs naturally in the plant feverfew (Tanacetum parthenium) and also promotes the ubiquitination of MDM2 and activates p53 cellular functions. Uses: 5-ht antagonist; anti-tumor; anti-cancer; antimycobacterial; anti-inflammatory. Alternative Names: NSC-157035; NSC 157035; NSC157035. Grades: >98%. CAS No. 20554-84-1. Molecular formula: C15H20O3. Mole weight: 248.32.
Parvisporin
It is a neuritogenic agent produced by the strain of Stachyborrys parvispora F4708. It promotes the enlargement of the neural sinus of P12 cells, and the effect of Stachybotrin C is obvious, but the effect of Parvisporin is weak. Molecular formula: C23H34O5. Mole weight: 390.51.
Parvodicin A
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. Alternative Names: Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranuronosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-81-0. Molecular formula: C81H84N8O29Cl2. Mole weight: 1704.48.
Parvodicin B1
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). It acts by inhibiting the synthesis of bacterial cell wall. Alternative Names: Antibiotic A-40926 A0; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-82-1. Molecular formula: C82H86N8O29Cl2. Mole weight: 1718.50.
Parvodicin B2
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). It acts by inhibiting the synthesis of bacterial cell wall. Alternative Names: Antibiotic A-40926 A1; Antibiotic A 40926 factor A; Antibiotic A 40926A; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxoundecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-83-2. Molecular formula: C82H86N8O29Cl2. Mole weight: 1718.50.
Parvodicin C1
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. Parvodicin C1 and C2 have stronger antibacterial effects than Parvodicin C3 and C4. The antibacterial activity of Parvodicin C is 1-4 times stronger than Tecomycin and 2-4 times stronger than vancomycin. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). The half-life of Parvodicin C1 is longer in vivo than vancomycin and Archeomycin. Alternative Names: Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-b-D-glucopyranuronosyl]-42-O-a-D-mannopyranosyl-N15-methyl-; A 40926B; A 40926 B0; Antibiotic A 40926 factor B0; Antibiotic A 40926B. CAS No. 110882-84-3. Molecular formula: C83H88N8O29Cl2. Mole weight: 1732.53.
Parvodicin C2
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. Parvodicin C1 and C2 have stronger antibacterial effects than Parvodicin C3 and C4. The antibacterial activity of Parvodicin C is 1-4 times stronger than Tecomycin and 2-4 times stronger than vancomycin. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). The half-life of Parvodicin C1 is longer in vivo than vancomycin and Archeomycin. Alternative Names: Antibiotic A-40926 B1; Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranuronosyl)-42-o-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 110882-85-4. Molecular formula: C83H88N8O29Cl2. Mole weight: 1732.53.
Parvodicin complex
It is produced by the strain of Actinomadura paroosalo. It's a glycopeptide antibiotic. It has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and enterococcus faecalis. Parvodicin C1 and C2 have stronger antibacterial effects than Parvodicin C3 and C4. The antibacterial activity of Parvodicin C is 1-4 times stronger than Tecomycin and 2-4 times stronger than vancomycin. The terminal branching activity of lipid chains is greater than straight chains (C1>C2>C3>C4, B1>B2), and the chain length is greater than short chains (C2>B). The half-life of Parvodicin C1 is longer in vivo than vancomycin and Archeomycin. Alternative Names: A 40926 complex. Grades: >95% by HPLC. CAS No. 187888-13-7. Molecular formula: C83H88Cl2N8O29 (for C1). Mole weight: 1732.53.
Paspalinine
Paspalinine is a tremorgenic mycotoxin extracted from the fermentation broth of Aspergillus flavus OUCMDZ-2205. It can inhibit the combination of [125I]charybdotoxin (ChTX) to maxi-K channels in bovine aortic smooth muscle sarcolemmal membranes. It displays tremorgenic action due in part to their inhibition of GABAA receptor function. It shows insecticidal properties. Alternative Names: 4H-3,15a-Epoxy-1-benzoxepino(6',7':6,7)indeno(1,2-b)indol-4-one, 2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R-(3alpha,5balpha,7abeta,13balpha,13cbeta,15aalpha))-; 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-. Grades: ≥98%. CAS No. 63722-91-8. Molecular formula: C27H31NO4. Mole weight: 433.54.
Patagonic acid
Patagonic acid is a dibenzofuran compound obtained from lichen bunodophoron patagonicum. Alternative Names: Benzoic acid, 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-6-(2-oxononyl)-; 2-Hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-6-(2-oxononyl)benzoic acid. CAS No. 158202-35-8. Molecular formula: C25H30O8. Mole weight: 458.5.
Paulomenol A
It is produced by the strain of Str. paulus 273. It has the effect of anti-gram-positive bacteria including Staphylococcus aureus, streptococcus pyogenes, streptococcus pneumoniae and so on. Alternative Names: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-[(2S)-2-methyl-1-oxobutoxy]ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; 4'-De-O-(2-Isothiocyano-2-Butenoyl)Pauromycin A. CAS No. 94739-81-8. Molecular formula: C29H43NO16. Mole weight: 661.65.
Paulomenol B
It is produced by the strain of Str. paulus 273. It has the effect of anti-gram-positive bacteria including Staphylococcus aureus, streptococcus pyogenes, streptococcus pneumoniae and so on. Alternative Names: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-(2-methyl-1-oxopropoxy)ethyl]-a-L-lyxo-hexopyranosyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; 4'-De-O-(2-isothiocyano-2-butenoyl)paulomycin B. CAS No. 97670-28-5. Molecular formula: C28H41NO16. Mole weight: 647.62.
Paulomycin A
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Alternative Names: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-[(2S)-2-methyl-1-oxobutoxy]ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 81988-77-4. Molecular formula: C34H46N2O17S. Mole weight: 786.80.
Paulomycin A2
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Alternative Names: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(S)-1-(3-methyl-1-oxobutoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 101411-68-1. Molecular formula: C34H46N2O17S. Mole weight: 786.80.
Paulomycin B
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacteria effect, and it has inhibitory effect on staphylococcus aureus resistant to penicillin, streptomycin, neomycin and macrolide antibiotics. The antibacterial activity of Paulomycin A, A1 and B are stronger than other components. Alternative Names: 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-3-O-methyl-4-C-[(1S)-1-(2-methyl-1-oxopropoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-. CAS No. 81988-76-3. Molecular formula: C33H44N2O17S. Mole weight: 772.77.
Paxilline
A tremorgenic mycotoxin isolated from species of penicillium, acremonium and emericella. It selectively blocks high-conductance ca2+-activated potassium channels and inhibits binding to the cerebellar inositol 1,4,5-triphosphate (insp(3)) receptor. Grades: >99% by HPLC. CAS No. 57186-25-1. Molecular formula: C27H33NO4. Mole weight: 435.55.
PB-5266 A
PB-5266 A is a monobactam antibiotic isolated from the culture filtrate of Cytophaga johnsonae PB-5266. It exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to beta-lactam antibiotics. Alternative Names: Antibiotic PB-5266A. CAS No. 108065-94-7. Molecular formula: C13H19N5O10S. Mole weight: 437.39.
PB-5266 B
PB-5266 B is a monobactam antibiotic isolated from the culture filtrate of Cytophaga johnsonae PB-5266. It exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to beta-lactam antibiotics. Alternative Names: Antibiotic PB-5266B. CAS No. 108065-95-8. Molecular formula: C13H19N5O11S. Mole weight: 453.38.
PB-5266 C
PB-5266 C is a monobactam antibiotic isolated from the culture filtrate of Cytophaga johnsonae PB-5266. It exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to beta-lactam antibiotics. Alternative Names: Antibiotic PB-5266C. CAS No. 108065-96-9. Molecular formula: C12H17N5O10S. Mole weight: 423.36.
PC-766B
PC-766B is a 16-membered macrolide antibiotic produced by nocardia brasiliensis. It is active against gram-positive bacteria, and some fungi and yeasts, but is inactive against gram-negative bacteria. It shows antitumor activity against murine tumor cells in vitro and in vivo, and weak inhibitory activity against na/K-atpase in vitro. Alternative Names: PC 766B. Grades: >95% by HPLC. CAS No. 108375-77-5. Molecular formula: C43H68O12. Mole weight: 777.0.
PD-116152
PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp. Uses: Pd-116152 has antitumor activity. Alternative Names: PD-116,152; PD116,152; PD 116,152; PD116152; PD 116152; 6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester; Methyl 6-formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylate. Grades: >98 %. CAS No. 101708-64-9. Molecular formula: C16H12N2O6. Mole weight: 328.28.
PD-116779
PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class. Uses: Pd-116779 is a novle antitumor antibiotic. Alternative Names: PD116,779; PD 116,779; PD-116,779; PD116779; PD 116779; 3,4-Dihydro-2,3,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; 2,3,8-Trihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. Grades: >98 %. CAS No. 102674-89-5. Molecular formula: C19H14O6. Mole weight: 338.31.
PD-118576
PD-118576 is an antitumor macrolide antibiotic produced by Streptomyces sp. WP 3913. It exhibits moderate activity against bacteria and fungi. Alternative Names: PD 118576; PD118576; PD-118,576; PD 118,576; PD118,576. CAS No. 100632-37-9. Molecular formula: C33H52O8. Mole weight: 576.8.
Pecilocin
It is originally isolated from Pacilomyces varioti var. antibioticu K-5201 (ATCC-13435). Pecilocin has anti-fungal and bacterial effects, but the anti-bacterial effect is weak. Alternative Names: variotin; Leofungine; NSC 291839; Pecilocinum; 1-(8-Hydroxy-6-methyl-1-oxo-2,4,6-dodecatrienyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-(8-hydroxy-6-methyl-2,4,6-dodecatrienoyl)-, (E,E,E)-(R)-. Grades: ≥98%. CAS No. 19504-77-9. Molecular formula: C17H25NO3. Mole weight: 291.38.
Pectolinarin
Pectolinarin, which can be found in the herbs of Cirsium japonicum DC, possesses anti-inflammatory activity and may inhibit eicosanoid formation in inflammatory lesions. It exerted a better analgesic effect than linarin. Pectolinarin also increased activity levels of GSH, GR, GCS, and GST, as well as SOD. Uses: Anti-inflammatory / analgesic / hepatoprotective. Alternative Names: 7-[[6-O-(a-L-rhamnopyranosyl)-b-D-glucopyranosyl]oxy]-5-hydroxy-6-methoxy-1-(4-methoxyphenyl)-4H-1-benzopyran-4-one; 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Pectolinaroside. Grades: >98%. CAS No. 28978-02-1. Molecular formula: C29H34O15. Mole weight: 622.57.
Pefloxacin
Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. Pefloxacin inhibits the activity of microbial DNA gyrase and topoisomerase IV. This disrupts DNA replication and prevents cell division. Alternative Names: 1584RB; 1589 RB; EU 5306 EU-5306; Pefloxacinium. Grades: >98%. CAS No. 70458-92-3. Molecular formula: C17H20FN3O3. Mole weight: 333.36.
Pefloxacin mesylate dihydrate
Pefloxacin Mesylate Dihydrate is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication. Uses: Anti-bacterial agents. Alternative Names: 1589 RB. Grades: >98%. CAS No. 149676-40-4. Molecular formula: C18H28FN3O8S. Mole weight: 465.49.
Pelagiomicin A
It is produced by the strain of Pelagiobacter variabilis. It has strong activity against gram-positive bacteria and gram-negative bacteria, but no activity against candida albicans. It's cytotoxic to HeLa cells, BALB3T3 and BALB3T3/H-ras cultured in vivo with IC50 (μg/mL) of 0.04, 0.2 and 0.07, respectively. In vivo it has weak inhibitory effect on leukemia P388. Alternative Names: Antibiotic 2088A; 3-Hydroxy-L-valine(6-carboxy-4-methoxy-1-phenazinyl)methylester; L-Valine, 3-hydroxy-, (6-carboxy-4-methoxy-1-phenazinyl)methyl ester; (S)-6-(((2-amino-3-hydroxy-3-methylbutanoyl)oxy)methyl)-9-methoxyphenazine-1-carboxylic acid. Grades: 95%. CAS No. 173485-80-8. Molecular formula: C20H21N3O6. Mole weight: 399.40.