BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Lupane-3β,16β-diol, 16-acetate | Lupane-3β,16β-diol, 16-acetate. Alternative Names: 16-acetate-Lupane-3β,16β-diol. CAS No. 107205-21-0. Molecular formula: C32H54O3. Mole weight: 486.77. |  |
| lupeol benzoate | lupeol benzoate. CAS No. 1617-69-2. Molecular formula: C37H54O2. Mole weight: 530.82. | |
| Luteolin-7-O-neohesperidoside | Luteolin-7-O-neohesperidoside is a flavone found in Veronicastrum sibiricum var. japonicum and in Teucrium gnaphalodes. Alternative Names: Lonicerin; Luteolin-7-rutinoside; Luteoline-7-rhamnoglucoside; 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-oxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-chromen-4-one; Scolymoside; Veronicastroside. Grades: >98%. CAS No. 25694-72-8. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Luteoreticulin | Luteoreticulin is a rare nitrophenyl pyranone closely related to aureothin, neoaureothin and its unusual photoisomers Antibiotics SNF4435C and D. It is a potent antitumor agent produced by Streptomyces luteoreticuli with pronounced immunosuppressive. It also has nematocide activity. Alternative Names: Griseulin; 6-[(1E,3E)-1,3-Dimethyl-4-(4-nitrophenyl)-1,3-butadien-1-yl]-4-methoxy-3-methyl-2H-pyran-2-one; (E,E)-6-[1,3-Dimethyl-4-(4-nitrophenyl)-1,3-butadienyl]-4-methoxy-3-methyl-2H-Pyran-2-one. Grades: >99% by HPLC. CAS No. 22388-89-2. Molecular formula: C19H19NO5. Mole weight: 341.36. | |
| Luzopeptin A | Luzopeptin A is a cyclic depsipeptide antibiotic produced by an actinomycete strain. It has anti-tumor activity. It is a potent inhibitor of HIV-1 reverse transcriptase. Alternative Names: Luzopeptin A;75580-37-9;Bbm-928 A;BBM-928A;Diacetyl-luzopeptin C;[(3R,7S,16S,17S,23R,27S,36S,37S)-37-acetyloxy-3,23-bis[(3-hydroxy-6-methoxyquinoline-2-carbonyl)amino]-7,27-bis(2-hydroxypropan-2-yl)-8,11,28,31-tetramethyl-2,6,9,12,15,22,26,29,32,35-decaoxo-5,25-dioxa-1,8,11,14,20,21,28,31,34,40-decazatricyclo[34.4.0.016,21]tetraconta-19,39-dien-17-yl] acetate;Luzopeptin C, 2,7-diacetate;Antibiotic BBM 928C, 2,7-diacetate;[37-Acetyloxy-3,23-bis[(3-hydroxy-6-methoxyquinoline-2-carbonyl)amino]-7,27-bis(2-hydroxypropan-2-yl)-8,11,28,31-tetramethyl-2,6,9,12,15,22,26,29,32,35-decaoxo-5,25-dioxa-1,8,11,14,20,21,28,31,34,40-decazatricyclo[34.4.0.016,21]tetraconta-19,39-dien-17-yl] acetate;Antibiotic BBM 928A;BRN 5725577;BBM 928A;SCHEMBL20614463;CHEBI:223532;DTXSID401317872;NSC308312;HY-130050;CS-0104626. Grades: >99% by HPLC. CAS No. 75580-37-9. Molecular formula: C24H32O6. Mole weight: 416.5. | |
| L-Valinamide | L-Valinamide. Alternative Names: Valinamide. CAS No. 4540-60-7. Molecular formula: C5H12N2O. Mole weight: 116.2. | |
| Lycomarasmin | It is produced by the strain of Fusarium oxysporum var. lycopersici, Fus. oxysporum var. vasinfectum, Fus. oxysporum var. melonis. It has the inhibitory effect of lactobacillus casei, and it is a plant toxin. Molecular formula: C9H15N3O7. Mole weight: 277.23. | |
| Lysobactin | Lysobactin, also known as katanosin B, is a potent antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis. Alternative Names: Katanosin B; Katanosin A, 7-L-isoleucine-. Grades: >98%. CAS No. 118374-47-3. Molecular formula: C58H97N15O17. Mole weight: 1276.48. | |
| Lysyl-asparagine | Lysyl-asparagine is a dipeptide composed of lysine and asparagine. Alternative Names: L-Lysyl-L-asparagine; lysylasparagine; Lys-Asn. CAS No. 19908-06-6. Molecular formula: C10H20N4O4. Mole weight: 260.29. | |
| Lysyl-glycine | Lysyl-glycine is a dipeptide composed of lysine and glycine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-lysylglycine; H-KG-OH; L-lysyl-glycine; Lys-Gly; L-Lys-Gly; Lys-Gly-OH; ((S)-2,6-Diamino-hexanoylamino)-acetic acid; N-L-Lysylglycine; N-Lysylglycine; Lysylglycine. Grades: ≥95%. CAS No. 7563-3-3. Molecular formula: C8H17N3O3. Mole weight: 203.24. | |
| Lysyl-phenylalanine | Lysyl-phenylalanine is a dipeptide composed of lysine and phenylalanine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: lysylphenylalanine; L-Phenylalanine, L-lysyl-; H-KF-OH; Lys-phe; L-lysyl-L-phenylalanine; L-Lys-L-Phe; L-Phenylalanine, N-L-lysyl-; N-(2,6-Diamino-1-hydroxyhexylidene)phenylalanine. Grades: ≥95%. CAS No. 6235-35-4. Molecular formula: C15H23N3O3. Mole weight: 293.36. | |
| Lysyl-serine | Lysyl-serine is a dipeptide composed of lysine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Lys-Ser; L-Serine, L-lysyl-; H-KS-OH; L-lysyl-L-serine; L-Serine, N-L-lysyl-; T Cell modulatory peptide. Grades: >90%. CAS No. 6665-19-6. Molecular formula: C9H19N3O4. Mole weight: 233.26. | |
| Lysyl-threonine | Lysyl-threonine is a dipeptide composed of lysine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: H-KT-OH; L-lysyl-L-threonine; lysylthreonine; L-Threonine, L-lysyl-; Lys-Thr; L-Threonine, N-L-lysyl-; L-Lys-L-Thr. Grades: >90% by HPLC. CAS No. 97791-84-9. Molecular formula: C10H21N3O4. Mole weight: 247.29. | |
| M-13-1 | It is an anthracycline antibiotic derived from Nocardia brasiliensis IFM-0075. Alternative Names: 4,11-Dihydroxy-2,8-dimethyl-7-methoxynaphthacene-5,12-dione. Molecular formula: C21H16O5. Mole weight: 348.35. | |
| M-230B | M-230B is originally isolated from Myxococcus xanthus M516E. It has anti-gram-negative and weak anti-gram-positive activity. Molecular formula: C35H59NO8. Mole weight: 621.84. | |
| M-4365 A1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 A1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Molecular formula: C31H53NO8. Mole weight: 567.75. | |
| M-4365 G1 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G1 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. And it also has a certain anti-Gram-negative bacteria activity. Molecular formula: C31H53NO7. Mole weight: 551.75. | |
| M-4365 G2 | It is produced by the strain of Micromonospora capillate MCRL 0940. M-4365 G2 is mainly resistant to Gram-positive bacteria and mycoplasma, and cross-resistance with other macrolide antibiotics. Alternative Names: SCHEMBL192993. Molecular formula: C31H51NO8. Mole weight: 565.74. | |
| MA144 G2 | MA144 G2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Alternative Names: Antibiotic MA 144G2; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,3,6-trideoxy-alpha-L-glycero-hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-hexopyranosyl)oxy)-2,5,7,10-tetrahydroxy-, methyl ester. CAS No. 66808-28-4. Molecular formula: C42H53NO16. Mole weight: 827.87. | |
| MA144 M1 | MA144 M1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Alternative Names: Antibiotic MA 144M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1,4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2,5,7-trihydroxy-, methyl ester; aclacinomycin M; MA-144M1. CAS No. 64431-68-1. Molecular formula: C42H55NO15. Mole weight: 813.88. | |
| MA144 M2 | MA144 M2 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Alternative Names: Antibiotic MA 144M2; 1-Hydroxy MA144 M1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-4-((O-2,3,6-trideoxy-alpha-L-glycero-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4) 2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester; MA-144M2. CAS No. 64474-89-1. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| MA144 S1 | MA144 S1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Alternative Names: aclacinomycin S; Antibiotic MA 144S1; MA 144 S1; L-2-Deoxyfucosyl-L-rhodosaminyl-aklavinone. CAS No. 64431-69-2. Molecular formula: C36H45NO13. Mole weight: 699.74. | |
| MA144 U1 | MA144 U1 is originally isolated from Streptomyces galilaeus MA144M1. It has anti-gram-positive bacteria and tumor effects. Alternative Names: Antibiotic MA 144U1; 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-6,11-dioxo-2-ethyl-4-O-((2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl(1-4)-O-3-(dimethylamino)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-2,7-dihydroxy-, methyl ester. CAS No. 65222-74-4. Molecular formula: C42H55NO16. Mole weight: 829.88. | |
| Macquarimicin A | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Alternative Names: 2,5-Ethanoindeno[4,5-e]oxecin-3,11,15-trione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7-hydroxy-12-methyl-, (1Z,5R*,7R*,8aS*,10aS*,12R*,13aR*,13bS*)-(+)-. CAS No. 165561-14-8. Molecular formula: C19H22O5. Mole weight: 330.37. | |
| Macquarimicin B | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Alternative Names: 3H-5,2-Ethanylylideneindeno[4,5-e]oxecin-3,11(1H)-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, (1S,5R,7R,8aS,10aS,12R,13aR,13bS)-; 3H-5,2-Ethanylylideneindeno[4,5-e]oxecin-3,11(1H)-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, [1S-(1R*,5S*,7S*,8aR*,10aR*,12S*,13aS*,13bR*)]-; 1H-2,5-Ethanoindeno[4,5-e]oxecin-3,11-dione,5,6,7,8,8a,10a,12,13,13a,13b-decahydro-7,15-dihydroxy-12-methyl-1-(2-oxopropyl)-, (1S,5R,7R,8aS,10aS,12R,13aR,13bS)-. CAS No. 165561-13-7. Molecular formula: C22H28O6. Mole weight: 388.45. | |
| Macquarimicin C | It is produced by the strain of Micromonospora chalcea. It's an antibiotic. Alternative Names: 2H-8,10a-Ethanocyclopenta[7,8]naphtho[2,3-c]pyran-3,10,12-trione,1,3a,5a,6,6a,7,8,11,11a,11b-decahydro-2-methyl-11-(2-oxopropyl)-,(2R,3aS,5aS,6aS,8R,10aR,11S,11aS,11bR)-; 10H-8,10a-Ethanocyclopenta[7,8]naphtho[2,3-c]pyran-3,10,12(2H)-trione,1,3a,5a,6,6a,7,8,11,11a,11b-decahydro-2-methyl-11-(2-oxopropyl)-, (2R,3aS,5aS,6aS,8R,10aR,11S,11aS,11bR)-. CAS No. 165561-12-6. Molecular formula: C22H26O5. Mole weight: 370.44. | |
| Macropa | Macropa. Alternative Names: 6,6'-((1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane-7,16-diyl)bis(methylene))dipicolinic acid. Grades: 95%. CAS No. 1128304-86-8. Molecular formula: C26H36N4O8. Mole weight: 532.59. | |
| Macrosphelide L | It is produced by the strain of Periconia byssoides OUPS-N133. It is a cell adhesion inhibitor. It inhibits the adhesion of HL-60 cells to HU-VEC cells with IC50 of 5.6 μmol/L. Molecular formula: C16H22O8. Mole weight: 342.34. | |
| Madindoline A | It is produced by the strain of Str. sp. K93-0711. It is an interleukin-6 inhibitor. It inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with IC50 of 8 μmol/L. It has no antimicrobial effect. Alternative Names: Antibiotic K93-0711 I1; (+)-madindoline A; Madindoline; 4-cyclopentene-1,3-dione, 4-butyl-2,5-dimethyl-2-[[(3aR,8aS)-2,3,3a,8a-tetrahydro-3a-hydroxy-8H-furo[2,3-b]indol-8-yl]methyl]-, (2R)-; (2R)-4-Butyl-2,5-dimethyl-2-[[(3aR,8aS)-2,3,3a,8a-tetrahydro-3a-hydroxy-8H-furo[2,3-b]indole-8-yl]methyl]cyclopenta-4-ene-1,3-dione. CAS No. 184877-64-3. Molecular formula: C22H27NO4. Mole weight: 369.45. | |
| Madindoline B | It is produced by the strain of Str. sp. K93-0711. It is an interleukin-6 inhibitor. It inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with IC50 of 30 μmol/L. It has no antimicrobial effect. Alternative Names: Antibiotic K93-0711 I2; (S)-4-butyl-2-(((3aR,8aS)-3a-hydroxy-2,3,3a,8a-tetrahydro-8H-furo[2,3-b]indol-8-yl)methyl)-2,5-dimethylcyclopent-4-ene-1,3-dione; (+)-Madindoline B. CAS No. 184877-65-4. Molecular formula: C22H27NO4. Mole weight: 369.45. | |
| Madumicin II | It is a cyclic depsipeptide antibiotic produced by the strain of Actinoplanes philippinences NRRL 5462. It mainly has the activity of anti-Gram-positive bacteria. Alternative Names: Antibiotic A-2315; A-2315A; Antibiotic A 2315A; Madumycin I, 15-deoxo-15-hydroxy-, (15S)-; A2315A; Madumycin II; Antibiotic A 17002F; Antibiotic A 15104V. CAS No. 58717-24-1. Molecular formula: C26H37N3O7. Mole weight: 503.59. | |
| Maduramicin Acid | Maduramicin Acid is a polyether antibiotic first isolated from actinomadura yunnaense (formerly nocardia sp. X-14868). It is a broad spectrum anti-coccidiosis agent, also active against treponema and cryptosporidium. It is also an ionic carrier, forming complexes with monovalent cations and having a higher affinity for K+ than Na+. Alternative Names: α-Maduramicin; Maduramycin; X 14868A; CL 273703; LL-C 23024-A; Antibiotic X 14868A. Grades: >98% by HPLC. CAS No. 79356-08-4. Molecular formula: C47H80O17. Mole weight: 917.13. | |
| MAK683 | MAK683 is an inhibitor of embryonic ectoderm development protein (EED) with potential antineoplastic activity. MAK683 binds to the domain of EED that interacts with trimethylated lysine 27 on histone 3 (H3K27me3), leading to a conformational change in the EED H3K27me3-binding pocket and preventing the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2). MAK683 is undergoing phase II clinical trials for the identification of antitumor activity. Alternative Names: MAK-683; MAK 683; MAK683; EED inhibitor-1; N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine. Grades: 98%. CAS No. 1951408-58-4. Molecular formula: C20H17FN6O. Mole weight: 376.395. | |
| Malioxamycin | It is produced by the strain of Str. lydicus No. 15748. It is an antibiotic that inhibits Gram-negative bacteria by inhibiting peptidoglycan synthesis in bacterial cell walls and promoting the formation of spheroplasts. Alternative Names: (R-(R*,S*))-(((2-Amino-3-methyl-1-oxobutyl)amino)oxy)butanedioic acid; Butanedioic acid, (((2-amino-3-methyl-1-oxobutyl)amino)oxy)-, (R-(R*,S*))-; (R)-[[[(S)-2-Amino-3-methyl-1-oxobutyl]amino]oxy]butanedioic acid. Grades: ≥95%. CAS No. 73020-27-6. Molecular formula: C9H16N2O6. Mole weight: 248.23. | |
| Maltophilin | It is produced by the strain of Stenotrophomonas maltophilia. It is a broad-spectrum antifungal antibiotic that has no antibacterial effect against gram-positive and gram-negative bacteria. Molecular formula: C29H38N2O6. Mole weight: 510.62. | |
| Maniwamycin A | It is produced by the strain of Str. prasinopilosus KC-7367. It has anti-fungal effect. Maniwamycin A has stronger anti-fungal effect than Maniwamycin B, but it has no anti-bacterial effect. Alternative Names: Antibiotic KA 7367A; KA 7367A; (S-(Z,E))-3-(1-Hexenyl-ONN-azoxy)-2-butanone. CAS No. 122566-70-5. Molecular formula: C10H18N2O2. Mole weight: 198.26. | |
| Maniwamycin B | It is produced by the strain of Str. prasinopilosus KC-7367. It has anti-fungal effect. Maniwamycin B has weaker anti-fungal effect than Maniwamycin A, but it has no anti-bacterial effect. Alternative Names: Antibiotic KA 7367B; KA 7367B; (S-(R*,R*-(Z,E)))-3-(1-Hexenyl-ONN-azoxy)-2-butanol; 2-Butanol, 3-(1-hexenyl-ONN-azoxy)-, (S-(R*,R*-(Z,E)))-. CAS No. 122547-71-1. Molecular formula: C10H20N2O2. Mole weight: 200.28. | |
| Mannosylglucosaminide | It is produced by the strain of Str. virginiae var. 4243-MTt1. It's an aminoglycoside antibiotic. It has anti-bacterium, mycobacterium and beer yeast effects. Trehalose does not counteract its antibacterial effect against Mycobacterium 607. Alternative Names: Mannosyl glucosaminide; Antibiotic 4243; 1-O-(2-Amino-2-deoxy-α-D-gluco-hexopyranosyl)-α-D-manno-hexopyranose; Mannotrehalosamine. CAS No. 14510-04-4. Molecular formula: C12H23NO10. Mole weight: 341.31. | |
| Manumycin | It is produced by the strain of Str. parvullus ETH 25000. It has anti-gram-positive bacterial effect, and has weak antibacterial effect on some mycobacteria and candida. Alternative Names: Manumycin A; NSC 622141; Antibiotic UCF 1C; 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-; (-)-Manumycin A; Antibiotic TMC 1F. Grades: ≥98%. CAS No. 52665-74-4. Molecular formula: C31H38N2O7. Mole weight: 550.64. | |
| Manumycin E | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Alternative Names: Asukamycin E; 2,4,6-Undecatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-10-methyl-, (2E,4E,6E)-. CAS No. 156250-43-0. Molecular formula: C30H34N2O7. Mole weight: 534.61. | |
| Manumycin F | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Alternative Names: Asukamycin; asukamycin A1; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-. CAS No. 156317-47-4. Molecular formula: C31H34N2O7. Mole weight: 546.62. | |
| Manumycin G | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Alternative Names: 2,4,6-Nonatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, (2E,4E,6E)-; 2,4,6-Nonatrienamide, N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, [1S-[1a,3(2E,4E,6E),5b,5(1E,3E,5E),6a]]-. Grades: ≥95%. CAS No. 156250-44-1. Molecular formula: C28H30N2O7. Mole weight: 506.55. | |
| Marasmic acid | It is produced by the strain of Marasmius conigenus 6890. It's a terpene antibiotic. It has anti-gram-positive bacteria effect. It also has anti-gram-negative bacteria, mycobacteria and fungi effect, but the effect is weak. Alternative Names: 3H,6H-3a,8b-Methano-1H-indeno[4,5-c]furan-4-carboxaldehyde,5a,7,8,8a-tetrahydro-3-hydroxy-7,7-dimethyl-1-oxo-, [3S-(3a,3ab,5ab,8ab,8bb)]-; NSC 318506; (3S,3aR,5aR,8aS,8bS)-3-hydroxy-7,7-dimethyl-1-oxo-5a,7,8,8a-tetrahydro-1H,3H,6H-3a,8b-methanoindeno[4,5-c]furan-4-carbaldehyde. CAS No. 2212-99-9. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Marcellomycin | Marcellomycin is produced by the strain of Actinosporangium bohemicum sp. nov. C-36145. It is a glycoside and quinone antibiotic. It has anti-gram-positive bacteria effect, especially has strong effect on streptococcus. It also has effect on individual gram-negative bacteria, but the activity is not strong. Marcellomycin was 4 times stronger than Musettamycin in the treatment of leukemia L-1210. Alternative Names: Morcellomycin; Pyrromycin; Mar; Rhodirubin E; Antibiotic MA 144U2; 1-Naphthacenecarboxylic acid, 4-((O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 63710-10-1. Molecular formula: C42H55NO17. Mole weight: 845.89. | |
| Marcfortine A | It is an indole alkaloid isolated from Aspergillus and Penicillium species. It has strong nematicidal activity. It is structurally related to paracetamol and can act by preventing cholinergic neuromuscular transmission. Alternative Names: UK 111866. Grades: >99% by HPLC. CAS No. 75731-43-0. Molecular formula: C28H35N3O4. Mole weight: 477.59. | |
| Maridomycin II | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. It has anti-mycobacterial effect but the effect is not strong. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Alternative Names: 9-Dihydrocarbomycin A; Antibiotic B 5050B; B 5050B; Antibiotic YL 704C4; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3-acetate 4B-(3-methylbutanoate), (12S,13S)-. Grades: ≥95%. CAS No. 35908-45-3. Molecular formula: C42H69NO16. Mole weight: 843.99. | |
| Maridomycin III | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Alternative Names: Platenomycin C1; Leucomycin V, 12,13-epoxy-12,13-dihydro-, 3,4B-dipropanoate, (12S,13S)-; Antibiotic B 5050C; Antibiotic YL 704C1; Turimycin EP3; Maridomycine; Maridomycinum. Grades: ≥95%. CAS No. 35775-82-7. Molecular formula: C41H67NO16. Mole weight: 829.97. | |
| Maridomycin IV | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Alternative Names: Antibiotic B 5050D; Turimycin EA3; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3-acetate 4B-propanoate, (12S,13S)-. Grades: ≥95%. CAS No. 35942-56-4. Molecular formula: C40H65NO16. Mole weight: 815.94. | |
| Maridomycin V | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Alternative Names: Antibiotic B 5050E; Turimycin EP2; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 4B-acetate 3-propanoate, (12S,13S)-. Grades: ≥95%. CAS No. 35942-57-5. Molecular formula: C40H65NO16. Mole weight: 815.94. | |
| Maridomycin VI | It is produced by the strain of Str. hygroscopicus B-5050. It's a macrolide antibiotic. It has the activity against gram-positive bacteria and mycoplasma. Serum dose not affect its antibacterial activity. It has the effect of protecting gram-positive bacterial infection mice, and the therapeutic dose is similar to styloleomycin. Alternative Names: Antibiotic B 5050F; B 5050F; Leucomycin V, 12,13-dihydro-12,13-epoxy-, 3,4B-diacetate, (12S,13S)-. Grades: ≥95%. CAS No. 35775-66-7. Molecular formula: C39H63NO16. Mole weight: 801.92. | |
| Marilactone | Marilactone is produced from the fungus Stachylidium sp. Alternative Names: 2H-Pyran-2-one, 6-ethyl-4-hydroxy-3-methyl-; 3-Methyl-4-hydroxy-6-ethyl-2-pyron. Grades: ≥98%. CAS No. 34818-17-2. Molecular formula: C8H10O3. Mole weight: 154.16. | |
| Marizomib | Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues. Alternative Names: (-)-Salinosporamide A; ML 858; ML858; ML-858; Marizomib; NPI 0052; NPI0052; NPI-0052; Salinosporamide A. Grades: ≥95%. CAS No. 437742-34-2. Molecular formula: C15H20ClNO4. Mole weight: 313.78. | |
| Martinomycin | It is produced by the strain of Str. salvialis. It's a polyether antibiotic. It has strong anti-gram-positive bacteria activity, but no anti-gram-negative bacteria activity. It also acts as a pesticide. Alternative Names: 2H-Pyran-2-acetic acid, 6-[[(2R,3R,4R,5S,7S,9R,10R)-3,9-dimethoxy-2,4,10-trimethyl-2-[(2S,2'R,5R,5'R)-octahydro-5'-[(2S,3S,4S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, (aR,2S,3S,4S,5S,6S)-; AntibioticK 41, 2-deoxy-2-methyl-; 2H-Pyran-2-acetic acid, 6-[[3,9-dimethoxy-2,4,10-trimethyl-2-[octahydro-5'-[tetrahydro-6-hydroxy-3,5,6-trimethyl-4-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]tetrahydro-2-hydroxy-4,5-dimethoxy-a,3,5-trimethyl-, [2S-[2a,2(S*),3a,4b,5a,6b[2S*[2R*,2'S*,5S*,5'S*[2R*,3R*,4R*(2S*,5R*,6S*),5S*,6R*]],3S*,4S*,5R*,7R*,9S*,10S*]]]-. Grades: ≥95%. CAS No. 160791-16-2. Molecular formula: C49H84O17. Mole weight: 945.18. | |
| Matairesinol 4'-O-β-gentiobioside | Matairesinol 4'-O-β-gentiobioside is a lignan found in the herbs of Trachelospermum jasminoides. Alternative Names: (3R,4R)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-[[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]methyl]oxolan-2-one. Grades: >98%. CAS No. 106647-14-7. Molecular formula: C32H42O16. Mole weight: 682.672. | |
| Mathemycin A | It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C71H132N2O24. Mole weight: 1397.80. | |
| Mathemycin B | It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C77H142N2O29. Mole weight: 1559.94. | |
| Matlystatin A | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect. Alternative Names: N-Acetyl-S-(4-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-5-methyl-3-oxoheptyl)-L-cysteine; N-acetyl-S-(4-(2-(2-(2-(hydroxyamino)-2-oxoethyl)heptanoyl)hexahydropyridazine-3-carboxamido)-5-methyl-3-oxoheptyl)-L-cysteine. CAS No. 140626-94-4. Molecular formula: C27H47N5O8S. Mole weight: 601.76. | |
| Matlystatin B | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.43 and 1.2, respectively. It has anti-gram-positive bacteria effect. Alternative Names: 1(2H)-Pyridazinebutanamide, tetrahydro-N-hydroxy-6-[[[2-methyl-1-(1-oxopropyl)butyl]amino]carbonyl]-g-oxo-b-pentyl-, [6S-[1(S*),6R*(1R*,2R*)]]-; Matlystatin B1. CAS No. 140923-32-6. Molecular formula: C22H40N4O5. Mole weight: 440.58. | |
| Matlystatin D | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively. Alternative Names: Matlystatin D1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140638-25-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
| Matlystatin E | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 19.3 and 59, respectively. Alternative Names: Matlystatin E1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxohexyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyheptylidene)amino]oxidanide. CAS No. 140638-26-2. Molecular formula: C26H42N6O6. Mole weight: 534.65. | |
| Matlystatin F | It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively. Alternative Names: Matlystatin F1; Pyrazolo(1,2-a)pyridazin-4-ium,5-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(5-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140667-42-1. Molecular formula: C27H44N6O6. Mole weight: 548.68. | |
| Maxacalcitol | Maxacalcitol is a non-calcemic vitamin D3 analog and a ligand of VDR-like receptors. Uses: Dermatologic agents. Alternative Names: 22-Oxacalcitriol; Prezios; Oxarol; 1alpha,25-Dihydroxy-22-oxavitamin D3. Grades: >98%. CAS No. 103909-75-7. Molecular formula: C26H42O4. Mole weight: 418.61. | |
| MC-031 | MC-031, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.6×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Alternative Names: O-Demethylchlorothricin. CAS No. 134637-04-0. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-032 | MC-032, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 10.5×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Alternative Names: O-Demethylhydroxychlorothricin. CAS No. 134615-17-1. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| MC-033 | MC-033, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 1.06×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Alternative Names: MC 033; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-15-9. Molecular formula: C49H61ClO16. Mole weight: 941.45. | |
| MC-034 | MC-034, an inhibitor of cholesterol biosynthesis, is produced by the strain of Streptomyces sp. A3761. It inhibited the synthesis of cholesterol from Mevalonic acid with IC50 of 18.3×10-5 mol/L. It also showed weak anti-gram-positive bacteria activity and inhibited the growth of HL-60 cells. Alternative Names: MC 034; Chlorothricin, 3B-O-de(3-chloro-6-methoxy-2-methylbenzoyl)-2A-hydroxy-, 4B-(3-chloro-6-methoxy-2-methylbenzoate). CAS No. 134615-16-0. Molecular formula: C49H61ClO17. Mole weight: 957.45. | |
| Meclocycline | Meclocycline is a tetracycline antibiotic derived from methacycline. It has a broad-spectrum antibacterial and antiprotozoan activity. Alternative Names: GS-2989; NSC 78502; (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; 7-Chloro-6-methylene-5-oxytetracycline; [4S-(4α,4aα,5α,5aα,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide. Grades: ≥98%. CAS No. 2013-58-3. Molecular formula: C22H21ClN2O8. Mole weight: 476.86. | |
| Meclocycline sulfosalicylate | Mecycline sulfosalicylate is a kind of tetracycline antibiotic, which shows broad-spectrum antibacterial and protozoal activity by combining 30S and 50S ribosomal subunits, preventing protein synthesis. Alternative Names: Mecloderm; Meclan; Meclutin. Grades: >98% by HPLC. CAS No. 73816-42-9. Molecular formula: C29H27ClN2O14S. Mole weight: 695.05. | |
| Megalomicin | Megalomicins are a family of macrolide antibiotics produced by the soil bacterium Micromonospora megalomicea. They exhibit antiparasitic, antiviral and antibacterial activity, and are effective against both Gram-positive and Gram-negative bacteria. CAS No. 129428-69-9. | |
| Megalomicin A | It is produced by the strain of Micromonospora megalomice var. megalomicea NRRL 3274. It is a macrolide antibiotic. It has anti-bacterial and mycobacterium activity, the activity is the strongest under alkaline condition, serum can reduce the activity of 20%-30%. It has protective effect on mice infected with Staphylococcus aureus, pneumococcus, E. coli and Pseudomonas aeruginosa. Alternative Names: Megalomicin; Antibiotic XK 41C; Antibiotic W-847-A; Megalomicina; Megalomicine; Megalomicinum; [3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-3,5,7,9,11,13-hexamethyl-7-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]oxy]-6-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione; Erythromycin, 3''-O-demethyl-6-O-[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]-. Grades: ≥95%. CAS No. 28022-11-9. Molecular formula: C44H80N2O15. Mole weight: 877.11. | |
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