BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Istamycin B | Istamycin B is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Alternative Names: L-chiro-Inositol, 4-amino-1-(2-amino-N-methylacetamido)-3-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-beta-D-lyxo-hexopyranosyl)-6-O-methyl-1,4,5-trideoxy-. CAS No. 72523-64-9. Molecular formula: C17H35N5O5. Mole weight: 389.49. |  |
| IT-143-A | IT-143-A is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Alternative Names: IT-143A. Molecular formula: C29H43NO4. Mole weight: 469.65. | |
| IT-143-B | IT-143-B is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Alternative Names: IT-143B. Grades: ≥95%. CAS No. 183485-34-9. Molecular formula: C28H41NO4. Mole weight: 455.63. | |
| IT-62-B | IT-62-B is originally isolated from Streptomyces sp. IT-62. It had moderate anti-Gram-positive bacteria activity (MIC 6.25-12.5 μg/mL), and anti-L1210, P388, adriamycin-resistant P388 and KB tumor cells activity. Molecular formula: C39H47NO15. Mole weight: 769.79. | |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Alternative Names: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. Grades: 98%. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. | |
| Izumenolide | It is produced by the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC50 concentration of TEM-2 β-lactamase was 0.01 μg/mL. Alternative Names: EM-4615-A; Oxacyclotriacont-3-en-2-one, 16,18-bis(sulfooxy)-30-(2-(sulfooxy)-9-undecenyl)-. CAS No. 76265-39-9. Molecular formula: C40H74O14S3. Mole weight: 875.20. | |
| Janthinocin A | It is produced by the strain of Janthinobacterium lividum. Janthinocin A has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. CAS No. 131086-52-7. Molecular formula: C57H84N12O16. Mole weight: 1193.34. | |
| Janthinocin B | It is produced by the strain of Janthinobacterium lividum. Janthinocin B has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. Alternative Names: 8-(alpha,beta-Didehydro-beta-hydroxytryptophan)janthinocin A; Janthinocin A, 8-(alpha,beta-didehydro-beta-hydroxytryptophan)-. CAS No. 131086-53-8. Molecular formula: C57H82N12O16. Mole weight: 1191.33. | |
| Janthitrem B | It is a tremorgenic mycotoxin produced by the strain of Penicillium Janthinellum. Alternative Names: 34-deoxy-34,35-didehydro-janthitrem E; (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-10,10,12,12,15b,15c-hexamethyl-2-(prop-1-en-2-yl)-2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-4bH-chromeno[5',6':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopenta[1,2-f]indole-3,4b,9-triol; 4bH-Pyrano[2'',3'':5',6']benz[1',2':6,7]indeno[1,2-b]pyrano[4',3':3,4]cyclopent[1,2-f]indole-3,4b,9-triol,2,3,5,6,6a,7,9,9a,10,12,15,15b,15c,16,17,17a-hexadecahydro-10,10,12,12,15b,15c-hexamethyl-2-(1-methylethenyl)-, (2R,3R,4bS,6aS,9S,9aR,15bS,15cR,17aS)-. CAS No. 73561-90-7. Molecular formula: C37H47NO5. Mole weight: 585.77. | |
| Javanicin | It is produced by the strain of Fusarium javanicum, etc. Javanicin is resistant to gram-positive bacteria and mycobacteria. Alternative Names: 5,8-Dihydroxy-6-methoxy-3-(2-oxopropyl)-1,4-naphthalenedione; 3-Acetonyl-5,8-dihydroxy-6-methoxy-2-methyl-1,4-naphthoquinone; BRN 2296055. Grades: ≥98% by HPLC. CAS No. 476-45-9. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Jawsamycin | It is produced by the strain of Streptoverticillium fervens. Jawsamycin had strong anti-filamentous fungal activity, and the MIC of Aspergillus Niger, Aureobasidium and Mucor was 0.05 μg/mL. Alternative Names: FR-900848; FR900848. CAS No. 120500-69-8. Molecular formula: C32H43N3O6. Mole weight: 565.70. | |
| JBIR-15 | JBIR-15 is an aspochracin derivative metabolized from Aspergillus sclerotiorum. It exhibits antifungal activity against C. albicans. Alternative Names: Antibiotic JBIR-15; (2E,4E,6E)-N-[(3S,6S,9S)-3,7-dimethyl-6-(1-methylethyl)-2,5,8-trioxo-1,4,7-triazacyclododec-9-yl]-2,4,6-octatrienamide. Grades: ≥95%. CAS No. 1198588-57-6. Molecular formula: C22H34N4O4. Mole weight: 418.53. | |
| JE-2147 | JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro. Alternative Names: JE-2147;186538-00-1;KNI-764;AG1776;AG 1776;CHEMBL300891;(4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-N-[(2-methylphenyl)methyl]-1,3-thiazolidine-4-carboxamide;(4r)-3-{(2s,3s)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)amino]-4-Phenylbutanoyl}-5,5-Dimethyl-N-(2-Methylbenzyl)-1,3-Thiazolidine-4-Carboxamide;(4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methyl. CAS No. 186538-00-1. Molecular formula: C32H37N3O5S. Mole weight: 575.72. | |
| Jenamidine A | It inhibited K-562 proliferation of chronic myeloid leukemia cells with Gl50 of 1.9 μg/mL. Molecular formula: C13H18N2O3. Mole weight: 250.29. | |
| Jietacin A | Jietacin A is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. Alternative Names: Jietacine A; BRN 5538455; 1-(Ethenyl-ONN-azoxy)-14-methyl-8-pentadecanone. CAS No. 109766-61-2. Molecular formula: C18H34N2O2. Mole weight: 310.47. | |
| Jietacin B | Jietacin B is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. CAS No. 109766-62-3. Molecular formula: C19H36N2O2. Mole weight: 324.50. | |
| Josamycin | Josamycin is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Alternative Names: YL-704A3; YL 704A3; YL 704 A3; Leucomycin A3; Turimycin A5; Kitasamycin A3; Josamycine. Grades: 95%. CAS No. 16846-24-5. Molecular formula: C42H69NO15. Mole weight: 828. | |
| Juglomycin A | Juglomycin A is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Alternative Names: (-)-Juglomycin A; 1,4-Naphthalenedione,5-hydroxy-2-[(2R,3R)-tetrahydro-3-hydroxy-5-oxo-2-furanyl]-. CAS No. 38637-88-6. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juglomycin B | Juglomycin B is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Alternative Names: (+/-)-juglomycin A. CAS No. 38637-89-7. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Jujuboside A | Jujuboside A may serve as a potential therapeutic agent for the treatment of Alzheimer?s disease. Uses: Therapeutic agent. Alternative Names: α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-; (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside. Grades: >98%. CAS No. 55466-04-1. Molecular formula: C58H94O26. Mole weight: 1207.35. | |
| Julimycin B2 | Julimycin B2 is originally isolated from Str. shiodaensis. It has anti-gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice of 3.10-12.5 mg/kg. Alternative Names: Julimycin II; JULIMYCIN B2-CA; Julimycin B-II; (2,2'-Bianthracene)-8,8',9,9',10,10'(5H,5'H)-hexone, 6,6',7,7'-tetrahydro-1,1',6-beta,6'-beta-tetrahydroxy-5-beta,5'-beta-bis(1-hydroxyethyl)-6,6'-dimethyl-,5,5'-diacetate. Grades: >98%. CAS No. 18126-05-1. Molecular formula: C38H34O14. Mole weight: 714.67. | |
| Juvenimicin A2 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A2 can resist gram-positive bacteria and individual gram-negative bacteria. Alternative Names: BRN 1413776; 6-De(2-oxoethyl)-4'-deoxy-6-methylcirramycin A1. CAS No. 61417-47-8. Molecular formula: C30H51NO8. Mole weight: 553.73. | |
| Juvenimicin A3 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A3 can resist gram-positive bacteria and individual gram-negative bacteria. Alternative Names: Rosaramicin; Rosaramicina; Rosaramicine; Rosaramicinum; Antibiotic 67-694; NSC 175150; 3-Ethyl-7-hydroxy-2,8,12,16-tetramethyl-5,13-dioxo-9-((3,4,6-tridesoxy-3-dimethylamino-beta-O-xylo-hexopyranosyl)oxy)-4,17-dioxabicyclo(14.1.0)heptadec-14-en-10-acetaldehyd. CAS No. 35834-26-5. Molecular formula: C31H51NO9. Mole weight: 581.74. | |
| K-1115A | It is produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115A inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide (IC50 = 100 microM), and the production of collagenase in IL-1 alpha-stimulated rat synovial cells (IC50 = 60 microM). Alternative Names: K1115 A; 2-Anthracenecarboxylic acid, 9,10-dihydro-3,8-dihydroxy-9,10-dioxo-1-propyl-. CAS No. 208525-17-1. Molecular formula: C18H14O6. Mole weight: 326.30. | |
| K1115 B1 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B1 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Alternative Names: XR-573. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| K1115 B2 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B2 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Molecular formula: C23H26O9. Mole weight: 446.45. | |
| K-13 | K-13 is a noncompetitive inhibitor of angiotensin I converting enzyme from Micromonospora halophytica subsp. exilisia K-13. Alternative Names: L-Tyrosine, N-acetyl-L-tyrosyl-L-tyrosyl-3-hydroxy-, cyclic (1-3(sup 3))-ether. CAS No. 108890-90-0. Molecular formula: C29H29N3O8. Mole weight: 547.55. | |
| K252A | K252a, an analog of staurosporine, has been found to be a protein kinase inhibitor and exhibit antitumor activity at some extent. Alternative Names: NZ0550000; Antibiotic K 252a. Grades: ≥98% by HPLC. CAS No. 99533-80-9. Molecular formula: C27H21N3O5. Mole weight: 467.50. | |
| K-252b | A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K-252b exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases, notably myosin light chain kinase, camp-dependent protein kinase (PKA), protein kinase C (PKC) and cgmp-dependent protein kinase (PKG). Alternative Names: (9r,10s,12s)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid. Grades: >98% by HPLC. CAS No. 99570-78-2. Molecular formula: C26H19N3O5. Mole weight: 453.45. | |
| K-252c | K252c, a metabolite product of Nocardiopsis Sp., has been found to be a protein kinase C inhibitor and exhibit antiviral activities against GCV-sensitive and-resistant strains at some extent. Uses: K252c inhibits protein kinase c. its reported ic50 value of 214 nm on rat brain enzyme k252c is cytotoxic for a549 and p388 cancer celllines showing ic50 = 2-3 μm. Alternative Names: Staurosporine aglycone; K252C; 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one. Grades: ≥97%. CAS No. 85753-43-1. Molecular formula: C20H13N3O. Mole weight: 311.34. | |
| K 259-2 | K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase, was isolated from the cultured broth of Micromonospora olivasterospora K-259. IC50 values for the effect of K-259-2 against Ca2+ and calmodulin-stimulated activity of the enzyme preparations from bovine brain and heart were 6.6 and 2.9 microM, respectively. Alternative Names: K-259-2; 1,6,8-Trihydroxy-3-[(Z)-2-ethyl-2-butenyl]-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid. CAS No. 102819-46-5. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| K 41 | K 41 is originally isolated from Streptomyces hygroscopicus K-41 with anti-gram-positive bacteria activity. Alternative Names: (29S)-9,13:17,20:21,24-trianhydro-4,8,10,12,14,18,19,22,23,26,28,30-dodecadeoxy-4,12,14,26,28-pentamethyl-6,16-di-C-methyl-5,6,11,15-tetra-O-methyl-27-O-[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]-L-xylo-L-manno-α-D-gluco-L-ribo-α-L-gluco-D-glycero-3,13,29-triacontotriulo-13,16-furanose-3,7:29,25-dipyranosonic acid. CAS No. 53026-37-2. Molecular formula: C48H82O18. Mole weight: 947.15. | |
| KA 7038IV | KA 7038IV is originally isolated from Streptomyces sp. KA-7038 with anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. Alternative Names: Antibiotic KA 7038IV; BRN 1387553; 2-Amino-3,6-dihydroxy-4-methoxy-5-(methylamino)cyclohexyl 2,6-diamino-2,3,4,6-tetradeoxyhexopyranoside. CAS No. 73491-60-8. Molecular formula: C14H30N4O5. Mole weight: 334.41. | |
| Kaempferol 3-a-L-arabinopyranoside | Kaempferol 3-a-L-arabinopyranoside comes from the roots of Ligusticum jeholense Nakai et Kitag. Alternative Names: Kaempferol 3-O-α-L-arabinoside. Grades: 95%. CAS No. 99882-10-7. Molecular formula: C20H18O10. Mole weight: 418.35. | |
| Kaempferol-3-Glucuronide | Kaempferol-3-beta-O-glucuronide is a flavonoid glucuronide, which can be found in vegetables and deconjugated by microsomal β-glucuronidase from various human cells. Uses: Antioxidant. Alternative Names: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl-beta-D-glucopyranosiduronic acid. Grades: >98%. CAS No. 22688-78-4. Molecular formula: C21H18O12. Mole weight: 462.36. | |
| Kaempferol 3-O-(2''-O-glucosyl)rutinoside | Kaempferol-3-O-(2"-O-β-D- glucopyl)-β-D-rutinoside is a compound of the flavonoid class. Alternative Names: 2''-O-Glucosylnicotiflorin. Grades: >98%. CAS No. 55696-58-7. Molecular formula: C33H40O20. Mole weight: 756.66. | |
| Kaempferol 3-O-sophoroside | Kaempferol 3-β-Sophoroside is a derivative of Kaempferol with antibacterial and antiviral activities. Alternative Names: Sophoraflavonoloside; 3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one. Grades: >98%. CAS No. 19895-95-5. Molecular formula: C27H30O16. Mole weight: 610.521. | |
| Kaempferol 3-O-sophoroside-7-O-glucoside | Kaempferol 3-sophoroside-7-glucoside is a compound of the flavonoid class found in the stems of Equisetum hyemale L. Alternative Names: Kaempferol 3-O-beta-D-[beta-D-glucopyranosyl-(1->2)-glucopyranoside]-7-O-beta-D-glucopyranoside; Kaempferol 3-O-beta-D-sophoroside 7-O-beta-D-glucopyranoside; Kaempferol 3-O-beta-sophoroside 7-O-beta-glucoside. Grades: >98%. CAS No. 55136-76-0. Molecular formula: C33H40O21. Mole weight: 772.66. | |
| Kaempferol 3-sophoroside-7-rhamnoside | Kaempferol 3-sophoroside-7-rhamnoside is a compound of the flavonoid class found in the herbs of Elaeagnus multiflora Thunb. Grades: >98%. CAS No. 93098-79-4. Molecular formula: C33H40O20. Mole weight: 756.66. | |
| Kaempferol tetramethyl ether | Kaempferol tetramethyl ether, a natural product found in Bryobium eriaeoides and Meistera koenigii, is a PPARγ agonist that can improve insulin sensitivity by increasing the levels of adiponectin. Alternative Names: Tetramethylkaempferol; 4H-1-Benzopyran-4-one, 3,5,7-trimethoxy-2-(4-methoxyphenyl)-; 3,5,7-Trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Flavone, 3,4',5,7-tetramethoxy-; 2-(4-Methoxyphenyl)-3,5,7-trimethoxy-4-oxo-4H-1-benzopyran; 3,4',5,7-Tetramethoxyflavone; 3,5,7,4'-Tetra-O-methylkaempferol; 3,5,7,4'-Tetramethoxyflavone; 3,5,7-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; O-Tetramethylkaempferol. Grades: ≥95%. CAS No. 16692-52-7. Molecular formula: C19H18O6. Mole weight: 342.34. | |
| Kajiichigoside F1 | Kajiichigoside F1 is a triterpenoid compound found in the roots of Rosa rugosa. Kajiichigoside F1 exhibits anti-inflammatory and hepatoprotective activities in vivo and antiviral activity in vitro. Alternative Names: [(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,2R,4aS,6aR,6aS,6bR,8aR,10S,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate. Grades: >98%. CAS No. 95298-47-8. Molecular formula: C36H58O10. Mole weight: 650.85. | |
| Kalafungin | Kalafungin is a quinone antibiotic produced by the strain of Str. tanashiensis Kala (NRRL 3215). It has anti-gram-positive bacterial and fungal effects as well as anti-parasite activity. Alternative Names: Kalamycin; NSC137443; Antibiotic U-19,718; 3,3a,5,11b-Tetrahydro-7-hydroxy-5-methyl-2H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione. Grades: ≥95%. CAS No. 11048-15-0. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Kalimantacin A | Kalimantacin A is originally isolated from Alcaligenes sp. YL-02632S. It has anti-Gram-positive bacteria (including multi-drug resistant bacteria) and some gram-negative bacteria activities. CAS No. 174513-95-2. Molecular formula: C30H48N2O7. Mole weight: 548.71. | |
| Kanamycin acid disulfate | Kanamycin acid sulfate is an aminoglycoside antibiotic produced by Streptomyces. Alternative Names: Kanamycin A disulfate. CAS No. 64013-70-3. Molecular formula: C18H40N4O19S2. Mole weight: 680.65. | |
| Kanamycin B Sulfate | Antibiotic complex is produced by Streptomyces kanamyceticus Okami and Umezawa from Japanese soil. Kanamycin B is an aminoglycoside antibiotic with activity against gram-negative bacteria. Uses: Anti-bacterial agents. Alternative Names: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine Sulfate; Aminodeoxykanamycin Sulfate; Bekanamycin Sulfate; Kanendomycin Sulfate. Grades: >95%. CAS No. 29701-07-3. Molecular formula: C18H37N5O10.H2O4S. Mole weight: 581.59. | |
| Kanchanamycin C | Kanchanamycin C is originally isolated from Str. olivaceus TU4018. It has anti-gram positive and negative bacteria, yeast and filamentous fungus action. Molecular formula: C54H91N3O17. Mole weight: 1054.31. | |
| Kanglemycin A | Kanglemycin A (KglA) is related to rifampicin, an antibiotic that functions by binding to bacterial RNA polymerase. KglA binds bacterial RNA polymerase at the rifampicin-binding pocket but maintains potency against RNA polymerases containing rifampicin-resistant mutations. KglA has antibiotic activity against rifampicin-resistant Gram-positive bacteria and multidrug-resistant Mycobacterium tuberculosis. Alternative Names: Antibiotic 1747; Rifamycin, 20-(1-(3-carboxy-2,2-dimethyl-1-oxopropoxy)ethyl)-20-demethyl-27-O-demethyl-1,4-dideoxy-27-O-(2,6-dideoxy-3,4-O-methylene-beta-D-ribo-hexopyranosyl)-1,4-dihydro-1,4-dioxo-; Kanglemeisu A; KglA. CAS No. 114153-91-2. Molecular formula: C50H63NO19. Mole weight: 982.03. | |
| Kapurimycin A1 | It is originally isolated from Str. sp. DO-15. Kapurimycin A1 can resist gram-positive bacteria and a few gram-negative bacteria. Alternative Names: [8-(Acetyloxy)-12-hydroxy-2-(2-methyl-3-propyloxiran-2-yl)-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. CAS No. 132412-65-8. Molecular formula: C27H26O9. Mole weight: 494.49. | |
| Kapurimycin A2 | It is originally isolated from Str. sp. DO-15. Kapurimycin A2 can resist gram-positive bacteria and a few gram-negative bacteria. Alternative Names: 8-Acetyloxy-2-(3-ethyl-2-methyloxiran-2-yl)-8,9,10,11-tetrahydro-12-hydroxy-4,11-dioxo-4H-anthra[1,2-b]pyran-5-acetic acid; [8-(Acetyloxy)-2-(3-ethyl-2-methyloxiran-2-yl)-12-hydroxy-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. Grades: ≥98%. CAS No. 132412-64-7. Molecular formula: C26H24O9. Mole weight: 480.46. | |
| Kapurimycin A3 | It is originally isolated from Str. sp. DO-15. Kapurimycin A3 can resist gram-positive bacteria and a few gram-negative bacteria. Alternative Names: 4H-Anthra(1,2-b)pyran-5-acetic acid, 8-(acetyloxy)-8,9,10,11-tetraahydro-12-hydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,11-dioxo-. Grades: >98%. CAS No. 129966-45-6. Molecular formula: C27H24O9. Mole weight: 492.47. | |
| Karalicin | Karalicin is produced by the strain of Pseudomonus fluorescens / putida SS-3. It inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC50 (μg/mL) of 0.004, 0.008, 0.016 and 0.016. Alternative Names: 3-O-Acetyl-1-deoxy-1-(4-methoxyphenyl)pentitol. Molecular formula: C14H20O6. Mole weight: 284.30. | |
| Katanosin A | Katanosin A is a peptide antibiotic originally isolated from Cytophaga sp. PBJ-5356. It has anti-gram-positive bacterial effect. Alternative Names: L-Serine, N-[threo-3-hydroxy-N2-[N-[N-[N-[N2-[N-[threo-3-hydroxy-N-[threo-b-hydroxy-N-(N-D-leucyl-L-leucyl)-L-phenylalanyl]-L-leucyl]-L-leucyl]-D-arginyl]-L-valyl]-L-allothreonyl]glycyl]-L-asparaginyl]-,b1-lactone. CAS No. 116103-86-7. Molecular formula: C57H95N15O17. Mole weight: 1262.45. | |
| Kaur-16-ene-3,18-diol, (3α,4α)- | Kaur-16-ene-3,18-diol, (3α,4α)-. Alternative Names: Kaur-16-ene-3α,18-diol (7CI); (3α,4α)-Kaur-16-ene-3,18-diol; 1H-2,10a-Ethanophenanthrene, kaur-16-ene-3,18-diol deriv; ent-3α-Hydroxykaur-16-en-18-ol. CAS No. 18524-59-9. Molecular formula: C20H32O2. Mole weight: 304.47. | |
| Kaur-16-ene-3α,18-diol, cyclic phosphorochloridate | Kaur-16-ene-3α,18-diol, cyclic phosphorochloridate. Alternative Names: Kaur-16-ene-3α,18-diol, cyclic phosphorochloridate (8CI). CAS No. 22488-83-1. Molecular formula: C20H30ClO3P. Mole weight: 384.88. | |
| Kauran-18-oic acid, 12α,17-dihydroxy-, methyl ester, (-)-, 16βH- | Kauran-18-oic acid, 12α,17-dihydroxy-, methyl ester, (-)-, 16βH-. Alternative Names: 16βH-Kauran-18-oic acid, 12α,17-dihydroxy-, methyl ester, (-)- (8CI). CAS No. 20108-26-3. Molecular formula: C21H34O4. Mole weight: 350.49. | |
| Kauran-18-oic acid, 12β,17-dihydroxy-, methyl ester, diacetate, (-)-, 16βH- | Kauran-18-oic acid, 12β,17-dihydroxy-, methyl ester, diacetate, (-)-, 16βH-. Alternative Names: 16βH-Kauran-18-oic acid, 12β,17-dihydroxy-, methyl ester, diacetate, (-)- (8CI). CAS No. 20108-23-0. Molecular formula: C25H38O6. Mole weight: 434.57. | |
| Kauran-18-oic acid, 16,17-dihydroxy-, methyl ester, (4α)- | Kauran-18-oic acid, 16,17-dihydroxy-, methyl ester, (4α)-. Alternative Names: Methyl ent-16α,17-dihydroxy-kauran-19-oate; ent-16α,17-Dihydroxy-kauran-19-oic acid methyl ester. CAS No. 3557-81-1. Molecular formula: C21H34O4. Mole weight: 350.49. | |
| Kauran-18-oic acid, 17-hydroxy-, methyl ester, (4α,16α)- | Kauran-18-oic acid, 17-hydroxy-, methyl ester, (4α,16α)-. Alternative Names: 16βH-Kauran-18-oic acid, 17-hydroxy-, methyl ester (7CI,8CI). CAS No. 3301-52-8. Molecular formula: C21H34O3. Mole weight: 334.49. | |
| Kaurane-3α,16,17,18-tetrol, cyclic 3,18:16,17-diacetal with acetone, (-)- | Kaurane-3α,16,17,18-tetrol, cyclic 3,18:16,17-diacetal with acetone, (-)-. Alternative Names: Kaurane-3α,16,17,18-tetrol, cyclic 3,18:16,17-diacetal with acetone, (-)- (8CI). CAS No. 19891-45-3. Molecular formula: C26H42O4. Mole weight: 418.61. | |
| Kaurane-3α,16,17-triol, cyclic 16,17-acetal with acetone, acetate, (-)- | Kaurane-3α,16,17-triol, cyclic 16,17-acetal with acetone, acetate, (-)-. Alternative Names: Kaurane-3α,16,17-triol, cyclic 16,17-acetal with acetone, acetate, (-)- (8CI). CAS No. 19891-32-8. Molecular formula: C25H40O4. Mole weight: 404.58. | |
| Kaurane-3α,18-diol, 16,17-epoxy-, diacetate, (-)- | Kaurane-3α,18-diol, 16,17-epoxy-, diacetate, (-)-. Alternative Names: Kaurane-3α,18-diol, 16,17-epoxy-, diacetate, (-)- (8CI). CAS No. 19891-49-7. Molecular formula: C24H36O5. Mole weight: 404.54. | |
| (+)-Kavain | Kavain is a kavalactone and the major constituent of the pepper plant kava (P. methysticum). Kavain has a positive modulatory effect on human recombinant α1β2, β2γ2L, αxβ2γ2L (x = 1, 2, 3 and 5), α1βxγ2L (x = 1, 2 and 3) and α4β2δ GABAARs expressed in Xenopus oocytes, particularly α4β2δ GABAAR. Uses: Anti-anxiety agents. Alternative Names: 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)-; (6R)-5,6-Dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one; 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]-; 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)-; (+)-Kawain; (R)-(+)-Kavain; d-Kawain; Gonosan; Kavain; Kawain; NSC 112162. Grades: ≥98%. CAS No. 500-64-1. Molecular formula: C14H14O3. Mole weight: 230.26. | |
| Kazusamycin A | A minor member of the leptomycin complex isolated from some streptomyces species; an hydroxylated analogue of leptomycin B, a nuclear export inhibitor; exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. Alternative Names: 3-HYDROXYLEPTOMYCIN B; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-; CL 1957B, PD 114721. Grades: >95% by HPLC. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73. | |
| Kazusamycin B | A minor component of the leptomycin complex produced by some streptomyces sp.; an hydroxylated analogue of leptomycin A, a nuclear export inhibitor; displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice; also possesses strong antibacterial and antifungal activity. Alternative Names: PD 124895; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-. Grades: >95% by HPLC. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.70. | |
| Kendomycin | Kendomycin is an endothelin receptor antagonist and proteasome inhibitor. It induces apoptosis in lymphoma. It is a potent antibacterial agent against gram-positive and gram-negative bacteria, including MRSA strains. Alternative Names: TAN 2162. Grades: >95% by HPLC. CAS No. 183202-73-5. Molecular formula: C29H42O6. Mole weight: 486.64. | |
| Kerriamycin A | Produced by the strain of Str. Violaceolatus, Kerriamycin A has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Alternative Names: Benz(a)anthracene-1,7,12(2H)-trione, 9-(2,6-dideoxy-3-O-((2S-(2alpha,5beta,6beta))-5-((2,6-dideoxy-beta-L-erythro-hexopyranos-3-ulos-1-yl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)-beta-D-arabino-hexopyranosyl)-3,4,4a,12b-tetrahydro-3,4a,8-trihydrox. CAS No. 98474-20-5. Molecular formula: C43H54O17. Mole weight: 842.88. | |
| Kerriamycin C | It is produced by the strain of Str. Violaceolatus. Kerriamycin C has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Alternative Names: Antibiotic A 32Y3; Benz[a]anthracene-1,7,12(2H)-trione,9-[2,6-dideoxy-3-O-[[2S-(2a,5b,6b)]-5-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-,[3R-(3a,4aa,12ba)]-. CAS No. 98495-38-6. Molecular formula: C37H46O15. Mole weight: 730.75. | |
| Ketomycin | It is produced by the strain of Str. sp. Tu99, Ketomycin is resistant to subtilis on the synthetic medium. Alternative Names: Antibiotic R-3; Antibiotic T 86A; Cyclohexenyl-1-glyoxalic acid; (R)-alpha-Oxo-3-cyclohexene-1-acetic acid; BRN 2964900. Grades: ≥98%. CAS No. 23364-22-9. Molecular formula: C8H10O3. Mole weight: 154.16. | |
| Kibdelin A | Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38. | |
| Kibdelin B | Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41. | |
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