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| Product | Description | |
|---|---|---|
| Hopane-7beta,22-diol | Hopane-7beta,22-diol. CAS No. 13416-66-5. Molecular formula: C30H52O2. Mole weight: 444.73. |  |
| Hormaomycin | Hormaomycin is an ester peptide antibiotic produced by Streptomyces griseoflavus. It is a signal transmitting substance between cells, which interferes with the formation of some streptomyces gas hyphae and the production of secondary metabolites. It also has anti-Gram-positive bacteria effect. CAS No. 121548-21-8. Molecular formula: C55H69ClN10O14. Mole weight: 1129.65. | |
| Hormaomycin B | Hormaomycin B is an cyclic depsipeptide antibiotic from a Marine Mudflat-Derived Streptomyces sp. It has a significant inhibitory effect on both Gram-positive and Gram-negative bacteria. Molecular formula: C54H67ClN10O14. Mole weight: 1115.62. | |
| Hormaomycin C | Hormaomycin C is an cyclic depsipeptide antibiotic from a Marine Mudflat-Derived Streptomyces sp. It has a significant inhibitory effect on both Gram-positive and Gram-negative bacteria. Molecular formula: C54H67ClN10O14. Mole weight: 1115.62. | |
| Hortein | Hortein is a polyketide fungal metabolite isolated from H. werneckii. Grades: >95% by HPLC. CAS No. 346610-88-6. Molecular formula: C20H12O6. Mole weight: 348.31. | |
| Hosenkoside C | Hosenkoside C is a triterpenoid compound found in the Impatiens balsamina L. Alternative Names: HosenkosideC; Hosenkoside C; 156764-83-9; HY-N2251; AKOS037515120; AC-34211; CS-0019576. Grades: >98%. CAS No. 156764-83-9. Molecular formula: C48H82O20. Mole weight: 979.164. | |
| Hosenkoside F | Hosenkoside F is a triterpenoid compound found in the Impatiens balsamina L. Alternative Names: Hosenkoside F; 160896-45-7; HosenkosideF; HY-N2241; AKOS037515121; MS-31775; CS-0019564; Hosenkoside F (Synonyms: (+)-Hosenkoside F). Grades: >98%. CAS No. 160896-45-7. Molecular formula: C47H80O19. Mole weight: 949.138. | |
| Hosenkoside G | Hosenkoside G is a triterpenoid compound found in the Impatiens balsamina L. Grades: >98%. CAS No. 160896-46-8. Molecular formula: C47H80O19. Mole weight: 949.138. | |
| Hosenkoside M | Hosenkoside M is a triterpenoid compound found in the Impatiens balsamina L. Alternative Names: Hosenkoside M; 161016-51-9; (+)-HosenkosideM; (+)-Hosenkoside M; HY-N2244; AKOS037515123; MS-31975; CS-0019567; Hosenkoside M (Synonyms: (+)-Hosenkoside M). Grades: >98%. CAS No. 161016-51-9. Molecular formula: C53H90O24. Mole weight: 1111.279. | |
| HQNO | It is produced by the strain of Pseudomonas pyocyanea, P. aeruginosa, P. methanica. HQNO is a quinolone inhibitor that blocks NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR). It has weak anti-gram-positive bacterial activity. It can inhibit the microsomal respiratory chain and 5-lipoxygenase of cytochrome BC1 complex, and antagonize the antibacterial activity of dihydrostreptomycin. Alternative Names: Antibiotic KF 8940; 2-Heptyl-1-hydroxy-4-(1H)-quinolinone; 2-heptyl-4-hydroxyquinoline n-oxide; HOQNO; 2-Heptyl-4-quinolinol 1-oxide; 2-heptylquinolin-4-ol 1-oxide; 2-(n-Heptyl)-4-hydroxyquinoline N-oxide. Grades: ≥98%. CAS No. 341-88-8. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| HT-2 toxin | HT-2 toxin is a mycotoxin produced by Fusarium sp. Symptoms of poisoning are nausea, vomiting, diarrhea, and leukopenia. The acute toxicity is lower than trichothecene. Uses: This product is used as a reference standard in quantitative analysis of food stuffs. Alternative Names: Mycotoxin HT 2; Toxin HT 2. CAS No. 26934-87-2. Molecular formula: C22H32O8. Mole weight: 424.48. | |
| Huperzine B | Huperzine B is an alkaloid isolated from Huperzia serrata. It acts as an inhibitor of human brain AChE. Alternative Names: 12-Methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one; (4aR,5S,10bR)-12-methyl-2,3,4,4a,5,6-hexahydro-1H-5,10b-prop[1]eno-1,7-phenanthrolin-8(7H)-one. Grades: >98%. CAS No. 103548-82-9. Molecular formula: C16H20N2O. Mole weight: 256.34. | |
| Hybocarpone | Hybocarpone is a cytotoxic naphthomethine derivative derived from Lecanora Hybocarpa Mycobacterium licheniformis culture. It has anti-tumor activity. Alternative Names: Dinaphtho[2,3-b:2',3'-d]furan-5,7,12,13-tetrone, 12a,12b-diethyl-5a,6a,12a,12b-tetrahydro-1,3,4,5a,6a,8,9,11-octahydroxy-2,10-dimethyl-, (5aR,6aR,12aR,12bR)-rel-(-)- (9CI); rel-(-)-(5aS,6aS,12aS,12bS)-12a,12b-Diethyl-5a,6a,12a,12b-tetrahydro-1,3,4,5a,6a,8,9,11-octahydroxy-2,10-dimethyldinaphtho[2,3-b:2',3'-d]furan-5,7,12,13-tetrone. CAS No. 245063-71-2. Molecular formula: C26H24O13. Mole weight: 544.46. | |
| Hydramycin | Hydramycin is an anti-tumor antibiotic produced by Streptomyces purpurea P950-4. It has activity against Gram-positive bacteria. It inhibits B16-F10, Moser and HCT-116 cells with IC50s (μg/mL) of 0.0009, 0.0046 and 0.0026, respectively, which is 300-600 times that of mitomycin C. It has a broad anti-cancer spectrum and has a moderate effect on P388 leukemia, with a T/C of 145%. Molecular formula: C22H16O8. Mole weight: 408.36. | |
| Hydranthomycin | Hydranthomycin is an antibiotic produced by Streptomyces sp. K93-5305. It has moderate antifungal activity, and the MIC of Pyricularia oryzae is 25 μg/mL. It inhibits the growth of Euglena gracilis and has herbicidal activity. Molecular formula: C20H20O5. Mole weight: 340.37. | |
| Hydrolyzed Fumonisin B2 | Hydrolyzed Fumonisin B2 is a metabolite of Fumonisin B2, a mycotoxin produced by mold associated with corn. Alternative Names: Fumonisin AP2; Fumonisin HB2; Hydrolyzed Fumonisin B2; 3,5,14,15-Eicosanetetrol, 2-amino-12,16-dimethyl-, (2S,3S,5R,12S,14S,15R,16R)-; (2S,3S,5R,12S,14S,15R,16R)-2-Amino-12,16-dimethyl-3,5,14,15-eicosanetetrol. Grades: ≥97%. CAS No. 147985-10-2. Molecular formula: C22H47NO4. Mole weight: 389.61. | |
| Hydroxy acivicin | Hydroxy acivicin is an antitumor agent. Alternative Names: U 43795; U-43795. CAS No. 54549-02-9. Molecular formula: C5H7ClN2O4. Mole weight: 194.57. | |
| Hydroxyakalone | Hydroxyakalone is an inhibitor of Xanthosine oxidase (XOD, EC 1.2.3.2) produced by Agrobacterium aurantiacumn N81106. It inhibits XOD with an IC50 of 4.6 μmol/L, which is stronger than acathone (IC50 16.9 μmol/L). Alternative Names: 1h-pyrazolo[3,4-d]pyrimidine-3,6(2h,7h)-dione,4-amino-. CAS No. 182056-35-5. Molecular formula: C5H5N5O2. Mole weight: 167.13. | |
| Hydroxy-alpha-sanshool | Hydroxy-alpha-sanshool is a compound isolated from the genus Zanthoxylum. It stimulates D-hair afferent nerve fibers. Alternative Names: (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide. CAS No. 83883-10-7. Molecular formula: C16H25NO2. Mole weight: 263.381. | |
| Hydroxy-beta-sanshool | Hydroxy-beta-sanshool is a compound isolated from the genus Zanthoxylum. Alternative Names: (2E,6E,8E,10E)-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide. CAS No. 97465-69-5. Molecular formula: C16H25NO2. Mole weight: 263.381. | |
| Hydroxychlorothricin | Hydroxychlorothricin is an antibiotic of the chlorothricin group produced by Streptomyces sp. K818. It has anti-tumor effect and can prolong the survival period of ICR mice inoculated with Ehrlich cancer cells. Molecular formula: C50H63ClO17. Mole weight: 971.48. | |
| Hydroxy Eriobrucinol | Hydroxy Eriobrucinol. Alternative Names: 1H,7H-4,6-Dioxacyclobut[1,7]indeno[5,6-b]naphthalen-7-one, 1a,2,3,3a,10b,10c-hexahydro-2,10-dihydroxy-1,1,3a-trimethyl-, [1aR-(1aα,2α,3aα,10bα,10cα)]-; 1H,7H-4,6-Dioxacyclobut[1,7]indeno[5,6-b]naphthalen-7-one, 1a,2,3,3a,10b,10c-hexahydro-2,10-dihydroxy-1,1,3a-trimethyl-, (1aS,3aR,10bR,10cR)-; Hydroxyeriobrucinol. CAS No. 42259-07-4. Molecular formula: C19H20O5. Mole weight: 328.36. | |
| Hydroxymycotrienin A | Hydroxymycotrienin A is an Ansa antibiotic produced by Bacillus sp. BMJ958-62F4. It has the activity of inhibiting human neck tumor cell line, and its inhibitory effect on human papillomavirus (HPV) gene positive neck tumor cells (such as HeLa, CaSki, SiHa, etc.) is stronger than HPV gene negative cells. CAS No. 178550-61-3. Molecular formula: C36H48N2O9. Mole weight: 652.77. | |
| Hydroxymycotrienin B | Hydroxymycotrienin B is an Ansa antibiotic produced by Bacillus sp. BMJ958-62F4. It has the activity of inhibiting human neck tumor cell line, and its inhibitory effect on human papillomavirus (HPV) gene positive neck tumor cells (such as HeLa, CaSki, SiHa, etc.) is stronger than HPV gene negative cells. CAS No. 178550-62-4. Molecular formula: C36H48N2O9. Mole weight: 652.77. | |
| Hydroxynybomycin | Hydroxynybomycin is an antibiotic produced by Streptomyces D-57. Activity against gram-negative bacteria. Alternative Names: 2H,4H-Oxazolo(5,4,3-ij)pyrido(3,2-g)quinoline-4,10(11H)-dione, 6,8-bis(hydroxymethyl)-11-methyl-. CAS No. 63582-81-0. Molecular formula: C16H14N2O5. Mole weight: 314.29. | |
| Hydroxystrobilurin A | Hydroxystrobilurin A is an antifungal antibiotic produced by Pterula spec. 82168. It has anti-yeast and filamentous fungus activity with a MIC of 1-10 μg/mL. Molecular formula: C16H18O4. Mole weight: 274.31. | |
| Hygromycin B | Hygromycin B is an aminoglycoside antibiotic produced by Streptomyces hygroscopicus, Str. noboritoensis and Corynebacterium sp. It has anti-gram-positive bacteria, negative bacteria, mycobacteria, amoeba, spirochetes and anthelmintic effects. Uses: Anthelmintics. Alternative Names: Macromycin; O-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N3-methyl-D-streptamine; Antihelmycin; Hygromix 2.4; Hygromix-8; Hygrovetin; Hygrovetine. Grades: >98%. CAS No. 31282-04-9. Molecular formula: C20H37N3O13. Mole weight: 527.52. | |
| Hynapene A | Hynapene A is produced by the strain of Penicillum sp. FO-1611. The MIC (X 10-6 mol/L) for Eimeria tenella inhibition is 123. Alternative Names: 5-(1,3,4-Trihydroxy-2,6,8-trimethyldecalin)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(decahydro-1,3,4-trihydroxy-2,6,8-trimethyl-1-naphthalenyl)-. CAS No. 155111-89-0. Molecular formula: C18H28O5. Mole weight: 324.41. | |
| Hynapene B | Hynapene B is produced by the strain of Penicillum sp. FO-1611. The MIC (X 10-6 mol/L) for Eimeria tenella inhibition is 34.7. Alternative Names: 5-(1-Ene-3-oxo-2,6,8-trimethyldecalin)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(3,4,4a,5,6,7,8,8a-octahydro-2,6,8-trimethyl-3-oxo-1-naphthalenyl)-. Grades: 99%. CAS No. 155111-88-9. Molecular formula: C18H24O3. Mole weight: 288.38. | |
| Hynapene C | Hynapene C is produced by the strain of Penicillum sp. FO-1611. The MIC (X 10-6 mol/L) for Eimeria tenella inhibition is 34.7. Alternative Names: 5-(3-Ene-1-oxo-2,6,8-trimethyldecalin-2-yl)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(1,2,4a,5,6,7,8,8a-octahydro-2,6,8-trimethyl-1-oxo-2-naphthalenyl)-. CAS No. 155111-90-3. Molecular formula: C18H24O3. Mole weight: 288.38. | |
| Hypelcin A-I | Hypelcin A-I is originally isolated from Hypocrea peltata. It has anti-gram-negative bacterial and fungal activity. Alternative Names: Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Leu-Aib-Gly-Aib-Aib-Pro-Val-Aib-Aib-Gln-Gln-Leu-ol. CAS No. 93397-17-2. Molecular formula: C89H153N23O24. Mole weight: 1929.30. | |
| Hypelcin A-II | Hypelcin A-II is originally isolated from Hypocrea peltata. It has anti-gram-negative bacterial and fungal activity. Alternative Names: Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Leu-Aib-Gly-Aib-Aib-Pro-Val-Aib-Aib-Gln-Gln-Leu-ol. CAS No. 93397-16-1. Molecular formula: C88H151N23O24. Mole weight: 1915.27. | |
| Hypelcin A-III | Hypelcin A-III is originally isolated from Hypocrea peltata. It has anti-gram-negative bacterial and fungal activity. Alternative Names: Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Leu-Aib-Gly-Aib-Aib-Pro-Val-Aib-Iva-Gln-Gln-Leu-ol. Molecular formula: C90H155N23O24. Mole weight: 1943.33. | |
| Hypelcin A-IV | Hypelcin A-IV is originally isolated from Hypocrea peltata. It has anti-gram-negative bacterial and fungal activity. Alternative Names: Ac-Aib-Pro-Aib-Ala-Aib-Aib-Gln-Aib-Ile-Aib-Gly-Aib-Aib-Pro-Val-Aib-Aib-Gln-Gln-Leu-ol. CAS No. 93397-15-0. Molecular formula: C89H153N23O24. Mole weight: 1929.30. | |
| Hypeptin | Hypeptin is produced by the strain of Pseudomonas sp. PB-6269. Hypeptin has the activity of anti-anaerobic gram-positive bacteria and anti-anaerobic gram-negative bacteria (weakly), and also has the effect on aerobic gram-positive bacteria. Alternative Names: UNII-0V1I6WBK4F; L-Isoleucine, N-(N-(N-(N2-(N2-(N2-(N-L-alanyl-D-leucyl)-D-arginyl)-erythro-3-hydroxy-L-asparaginyl)-erythro-3-hydroxy-D-asparaginyl)-erythro-beta-hydroxy-L-tyrosyl)-threo-3-hydroxy-L-leucyl)-, lambda-lactone. Grades: >98%. CAS No. 124883-38-1. Molecular formula: C44H71N13O15. Mole weight: 1022.11. | |
| Hyperconfluentic acid | Hyperconfluentic acid is isolated from pseudobaeomyces pachycarpa. Alternative Names: 2-Heptyl-4-[[2-hydroxy-4-methoxy-6-(2-oxoheptyl)benzoyl]oxy]-6-methoxybenzoic acid. CAS No. 108529-21-1. Molecular formula: C30H40O8. Mole weight: 528.63. | |
| Hyperforin | Hyperforin is produced by the strain of Hypericum perforatum. It has anti-gram-positive bacterial and mycobacterium activity. Alternative Names: hiperforina; hyperforine; (1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione; Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-. Grades: >95%. CAS No. 11079-53-1. Molecular formula: C35H52O4. Mole weight: 536.78. | |
| Hyperhomosekikaic acid | Hyperhomosekikaic acid. CAS No. 103538-06-3. Molecular formula: C26H34O8. Mole weight: 474.54. | |
| Hyperlatolic acid | It is a new depside from the Lichens Dimelaena Oreina and Fuscidea Viridis. Alternative Names: Benzoic acid, 2-heptyl-6-hydroxy-4-[(2-hydroxy-4-methoxy-6-pentylbenzoyl)oxy]-. CAS No. 90332-20-0. Molecular formula: C27H36O7. Mole weight: 472.57. | |
| Hyperplanaic acid | Hyperplanaic acid is a compound obtained from the lichen lecanora planaica. CAS No. 156372-07-5. Molecular formula: C29H40O7. Mole weight: 500.62. | |
| Hypnophilin | Hypnophilin is produced by the strain of Pleurotellus hypnophilus 539. It has a variety of activities, including anti-gram-positive bacteria, negative bacteria, yeast, mold and tumor activities. Alternative Names: (-)-Hypnophilin; (3aR,3bβ,6aβ)-4β-Hydroxy-3aα,5,5-trimethyl-3-methylene-1α,7aα-epoxydecahydro-2H-cyclopenta[a]pentalene-2-one. CAS No. 80677-96-9. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Hypoconstictic acid | It is isolated from Usnea undulata Stirton (Usneaaceae), a fruticose lichen. Alternative Names: 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-3,7(1H)-dione, 1,4-dihydroxy-5-(hydroxymethyl)-10-methoxy-8,11-dimethyl-; 1,4-Dihydroxy-5-hydroxymethyl-10-methoxy-8,11-dimethyl-1H-benzo[e]furo[3',4':3,4]benzo[b][1,4]dioxepine-3,7-dione. CAS No. 78916-52-6. Molecular formula: C19H16O9. Mole weight: 388.32. | |
| Hypocrellin A | Hypocrellin A is a natural perylene quinine photosensitizer isolated from Hypocrella bambusae. It is a potent PKC inhibitor. Uses: Antiviral agents. Alternative Names: 7,19-dione; Isohypocrelin. Grades: 95%. CAS No. 77029-83-5. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Hyponine D | Hyponine D is a sesquiterpene alkaloid. Alternative Names: Hyponine D; 259823-31-9; hyponin DCHEMBL504037CHEBI:132388. Grades: >98%. CAS No. 259823-31-9. Molecular formula: C47H50N2O18. Mole weight: 930.913. | |
| Hyponine E | Hyponine E is a sesquiterpene alkaloid isolated from Tripterygium hypoglaucum. Alternative Names: (-)-Hyponine E. Grades: >98%. CAS No. 226975-99-1. Molecular formula: C45H48N2O19. Mole weight: 920.874. | |
| Hypophysciosporin | It is isolated from the lichen Erioderma phaeorhizum. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2-chloro-3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-, methyl ester; 2-chloro-3,8-dihydroxy-1,4,6,9-tetramethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid methyl ester. Grades: ≥95%. CAS No. 64662-23-3. Molecular formula: C19H17ClO7. Mole weight: 392.79. | |
| Hypoprotocetraric acid | It is a depsidone from lichen species of Cladonia genus (C. fimbriata, C. furcata, C. subulata, C. foliacea and C. rangiferina). Alternative Names: Coquimboic acid; 3,9-dihydroxy-1,4,7,10-tetramethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; Hypoprotocetrarsaeure; 3,8-Dihydroxy-1,4,6,9-tetramethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carbonsaeure; 1,4,6,9-Tetramethyl-3,8-dihydroxy-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid; Benzoic acid, 3-(2-carboxy-5-hydroxy-3,6-dimethylphenoxy)-4,6-dihydroxy-2,5-dimethyl-, ε-lactone. CAS No. 4665-2-5. Molecular formula: C18H16O7. Mole weight: 344.32. | |
| Hypostictic acid | It has moderate inhibitory activity against the growth of Mycobacterium tuberculosis. Alternative Names: Hypostatic acid; 1,4-Dihydroxy-10-methoxy-5,8,11-trimethyl-1H-benzo[e]furo[3',4':3,4]benzo[b][1,4]dioxepine-3,7-dione; 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-3,7(1H)-dione, 1,4-dihydroxy-10-methoxy-5,8,11-trimethyl-. Grades: ≥98%. CAS No. 68729-11-3. Molecular formula: C19H16O8. Mole weight: 372.33. | |
| Hypostrepsilic acid | Hypostrepsilic acid is a dibenzofuran from the cultured lichen mycobiont of Evernia esorediosa. CAS No. 154160-67-5. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Hypothamnolic acid | Hypothamnolic acid. Alternative Names: 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(3-carboxy-4,6-dihydroxy-2,5-dimethylphenyl) ester; 3-((3-carboxy-2-hydroxy-4-methoxy-6-methylbenzoyl)oxy)-4,6-dihydroxy-2,5-dimethylbenzoic acid; Hypothamnolinsaeure; 2-hydroxy-4-methoxy-6-methyl-isophthalic acid-1-(3-carboxy-4,6-dihydroxy-2,5-dimethyl-phenyl ester). CAS No. 573-36-4. Molecular formula: C19H18O10. Mole weight: 406.34. | |
| IB-00208 | IB-00208, a new cytotoxic polycyclic xanthone produced by Actinomadura sp. It also has anti-Gram-positive bacteria activity (MIC=0.09-1.4 nmol/L). Molecular formula: C36H34O12. Mole weight: 658.65. | |
| IC-202-A | IC-202-A shows immunosuppressive activity, with IC50 of 3.6 μg/mL as determined by MLCR, and has a strong inhibitory effect on Blastogensis induced by ConA or lipopolysaccharide (LPS). Molecular formula: C27H52N6O7. Mole weight: 572.74. | |
| IC202B | IC202B shows immunosuppressive activity, with IC50 of 3.6 μg/mL as determined by MLCR, and has a strong inhibitory effect on Blastogensis induced by ConA or lipopolysaccharide (LPS). Alternative Names: N-(5-aminopentyl)-N-hydroxy-N'-[5-(hydroxy{4-[(5-nitropentyl)amino]-4-oxobutanoyl}amino)pentyl]butanediamide; IC-202B. Molecular formula: C23H44N6O8. Mole weight: 532.63. | |
| ICA-069673 | ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Alternative Names: ICA 069673; ICA069673. CAS No. 582323-16-8. Molecular formula: C11H6ClF2N3O. Mole weight: 269.63. | |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti | |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Alternative Names: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Molecular formula: C22H30N6O. Mole weight: 394.52. | |
| I-Cholestane | I-Cholestane. Alternative Names: i-Cholestane; 3,5-Cyclocholestane; (3aR,3bS,5aR,6R,8aS,8bS)-3a,5a-dimethyl-6-((R)-6-methylheptan-2-yl)hexadecahydrocyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalene; (3α,5α)-3,5-Cyclocholestane. CAS No. 465-56-5. Molecular formula: C27H46. Mole weight: 370.65. | |
| ICM0201 | It is originally isolated from Cunninghamella sp. F-1490. ICM0201 can inhibit the formation of osteoclasts in mouse bone marrow cells with IC50 of 0.78 μg/mL. Alternative Names: ICM 0201; ICM-0201. Molecular formula: C12H13NO6. Mole weight: 267.23. | |
| Icotinib hydrochloride | Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Alternative Names: Icotinib HCl; BPI-2009; BPI 2009; BPI2009. Grades: >98%. CAS No. 1204313-51-8. Molecular formula: C22H22ClN3O4. Mole weight: 427.88. | |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Alternative Names: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grades: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Ikarugamycin | An unusual pentacyclic tetramic acid produced by streptomyces phaeochromogenes; potent activity against the protozoan, trichomonas vaginalis; demonstrates selective gram positive antibacterial activity, and anti-ulcer activity possibly via inhibition of H. Pylori; inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages, blocks PMA and nef-mediated cell surface CD4 down-regulation, and inhibits clathrin-coated pit-mediated endocytosis; a useful agent for studying the process of endocytosis. Alternative Names: 14,17-Metheno-17H-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(1H)-trione. Grades: >99% by HPLC. CAS No. 36531-78-9. Molecular formula: C29H38N2O4. Mole weight: 478.62. | |
| Ilamycin A | Ilamycin A is produced by the strain of Str. islandicus A-165-Z1. It is resistant to mycobacteria, including human mycobacterium tuberculosis, and also to streptomycin resistant bacteria. Grades: >97%. CAS No. 11006-41-0. Molecular formula: C54H75N9O12. Mole weight: 1042.22. | |
| Ilicicolin A | Ilicicolin A is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibited Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells was 0.2 μg/mL. Alternative Names: LL-Z 1272-alpha; 3-chloro-4,6-dihydroxy-2-methyl-5-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzaldehyde. Grades: >98%. CAS No. 22581-06-2. Molecular formula: C23H31ClO3. Mole weight: 390.94. | |
| Ilicicolin B | Ilicicolin B is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibited Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells was 0.3 μg/mL. Alternative Names: 2,4-Dihydroxy-6-methyl-3-((2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl)benzaldehyde; LL-Z1272beta. Grades: >98%. CAS No. 22581-07-3. Molecular formula: C23H32O3. Mole weight: 356.50. | |
| Ilicicolin C | Ilicicolin C is originally isolated from Cylinddrocladium ilicicola MFC-870. It inhibits Bacillus carbonifera with the concentration of 6 μg/mL and its toxic concentration to Hela cells is 0.2 μg/mL. Alternative Names: LL-Z 1272delta; 3-Chloro-4,6-dihydroxy-2-methyl-5-((2E)-3-methyl-5-((1S,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl)-2-pentenyl)benzaldehyde. Grades: >95%. CAS No. 22562-67-0. Molecular formula: C23H31ClO4. Mole weight: 406.94. | |
| Illudin C2 | Illudin C2 is produced by the strain of Coprinus atramentarius ASI 20013. It has the effect of resisting bacterium and fungus, and the antibacterial activity is weak. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Illudin M | Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Alternative Names: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grades: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Illudin S | Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. Alternative Names: (-)-Illudin S; Lampterol; Lunamycin; (-)-1alpha,7beta,12-trihydroxy-2,9-illudadien-8-one; 2',3'-Dihydro-2',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. Grades: >98% by HPLC. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Imatinib | Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Alternative Names: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. Grades: >98%. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.60. | |
| Imbricaric acid | Imbricaric acid. Alternative Names: Benzoic acid, 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-pentylbenzoyl)oxy]-6-propyl-; Imbricarsaeure; 2-Hydroxy-4-(2-hydroxy-4-methoxy-6-pentyl-benzoyloxy)-6-propyl-benzoesaeure. CAS No. 491-57-6. Molecular formula: C23H28O7. Mole weight: 416.46. | |
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