BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Lanopylin B1 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 33 μmol/L. Alternative Names: 2-Methyl-3-[(E)-heptadecane-1-ylidene]-4,5-dihydro-3H-pyrrole. Molecular formula: C22H41N. Mole weight: 319.57. |  |
| Lanopylin B2 | It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 41 μmol/L. Molecular formula: C24H43N. Mole weight: 345.60. | |
| Lanostenyl benzoate | Lanostenyl benzoate. Alternative Names: 5α-Lanost-8-en-3β-ol, benzoate (6CI); Lanost-8-en-3-ol, benzoate, (3β)- (9CI). CAS No. 131896-72-5. Molecular formula: C37H56O2. Mole weight: 532.84. | |
| L-Argininol | L-Argininol. Alternative Names: (S)-1-(4-amino-5-hydroxypentyl)guanidine; H-Arg-ol. Molecular formula: C6H16N4O. Mole weight: 160.20. | |
| Lasallic acid | Lasallic acid is a tridepside from the lichen Lasallia asiae-orientalis. Alternative Names: 3-Carboxy-2,6-dihydroxy-4-methylphenyl 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoate; Benzoic acid, 4-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 3-carboxy-2,6-dihydroxy-4-methylphenyl ester. CAS No. 177795-28-7. Molecular formula: C24H20O11. Mole weight: 484.41. | |
| Lasalocid | It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria, protozoa and mycobacterium activity. It is added to feed to prevent coccidiosis in chickens. Alternative Names: Lasalocid A; Lasalocide; Lasalocidum; Antibiotic X 537A; 6-(7-(5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methylbenzoic acid, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*),5alpha,6beta))-. Grades: > 95%. CAS No. 25999-31-9. Molecular formula: C34H53O8. Mole weight: 590.80. | |
| Lasalocid B | It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Alternative Names: 3-Ethyl-6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R)-tetrahydro-5-ethyl-5-hydroxy-6α-methyl-2H-pyran-2-yl]tetrahydro-3-methylfuran-2-yl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxybenzoic acid. CAS No. 55051-86-0. Molecular formula: C35H56O8. Mole weight: 604.81. | |
| Lasalocid C | It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Alternative Names: Benzoic acid, 6-[3-ethyl-7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-5-methyl-6-oxononyl]-2-hydroxy-3-methyl-, [2R-[2a[2S*(3R*,4S*,5S*,7R*),3S*,5S*],5a,6b]]-. CAS No. 55051-84-8. Molecular formula: C35H56O8. Mole weight: 604.81. | |
| Lasalocid E | It is produced by the strain of Str. lasaliensis. It has anti-gram-positive bacteria and protozoa activity. It is added to feed to prevent coccidiosis in chickens. Alternative Names: Benzoic acid, 6-[(3R,4S,5S,7R)-5-ethyl-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]-tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3-methyl-6-oxononyl]-2-hydroxy-3-methyl-. CAS No. 55051-82-6. Molecular formula: C35H56O8. Mole weight: 604.81. | |
| L-Asparagine methyl ester | L-Asparagine methyl ester. Alternative Names: methyl L-asparaginate; asparagine methyl ester; H-Asn-OMe. Molecular formula: C5H10N2O3. Mole weight: 146.1. | |
| L-Asparaginol | L-Asparaginol. Alternative Names: Asparaginol; Asn-ol. CAS No. 36983-58-1. Molecular formula: C4H10N2O2. Mole weight: 118.1. | |
| L-Asparaginyl-L-aspartic acid | L-asparaginyl-L-aspartic acid is a dipeptide composed of asparagine and aspartic acid. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: H-ND-OH; L-asparagyl-L-aspartic acid; Asparaginyl-aspartate; Asn-Asp; L-Asn-L-Asp; L-Aspartic acid, L-asparaginyl-; (S)-2-((S)-2,4-Diamino-4-oxobutanamido)succinic acid. Grades: ≥95%. CAS No. 61365-15-9. Molecular formula: C8H13N3O6. Mole weight: 247.21. | |
| L-asparaginyl-L-threonine | L-asparaginyl-L-threonine is a dipeptide composed of asparagine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Asparaginyl-threonine; H-NT-OH; L-Threonine, L-asparaginyl-; N-L-Asparaginyl-L-threonine; Asn-Thr; L-Asn-L-Thr-OH; (S)-2-((S)-2-Amino-3-carbamoyl-propionylamino)-3-hydroxy-butyric acid. Grades: ≥98%. CAS No. 40043-76-3. Molecular formula: C8H15N3O5. Mole weight: 233.22. | |
| L-Aspartyl-L-Proline | L-Aspartyl-L-Proline is a dipeptide composed of aspartic acid and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Aspartyl-L-proline; Aspartyl-proline; L-α-Aspartyl-L-proline; Aspartylproline; Asp-pro; 1-L-alpha-aspartyl-L-Proline; (S)-1-((S)-2-Amino-3-carboxypropanoyl)pyrrolidine-2-carboxylic acid; L-alpha-Aspartyl-L-proline. Grades: ≥98%. CAS No. 42155-95-3. Molecular formula: C9H14N2O5. Mole weight: 230.22. | |
| Lateropyrone | An unusual heterocyclic metabolite isolated from fusarium avenaceum with antibacterial and antifungal activity. Alternative Names: Avenacein Y. Grades: >99% by HPLC. CAS No. 93752-78-4. Molecular formula: C15H10O8. Mole weight: 318.23. | |
| Lathosterol | Lathosterol is an intermediate in the biosynthesis of cholesterol. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol. Alternative Names: 5alpha-Cholest-7-en-3beta-ol; Cholest-7-en-3-ol; 7-Cholesten-3-beta-ol. Grades: >99%. CAS No. 80-99-9. Molecular formula: C27H46O. Mole weight: 386.65. | |
| Lavanducyanin | Lavanducyanin is a testosterone 5 alpha-reductase inhibitor isolated from Streptomyces sp. No. 9659. It exhibits weak activity against gram-positive bacteria. Alternative Names: WS-9659 A; WS-9659A; WS 9659 A. CAS No. 122228-60-8. Molecular formula: C22H24N2O. Mole weight: 332.4. | |
| Lavanduquinocin | It is produced by the strain of Str. viridochromogen. It is a protective agent of nerve cells and has the effect of reducing L-glutamate on cytotoxicity of neuronal hybridoma N18-RE-105 with ED50 of 15.5 nmol/L. Alternative Names: (R)-1-(2-hydroxypropyl)-2-methyl-6-((2,4,4-trimethylcyclohex-1-en-1-yl)methyl)-3H-carbazole-3,4(9H)-dione; 3H-Carbazole-3,4(9H)-dione, 1-(2-hydroxypropyl)-2-methyl-6-[(2,4,4-trimethyl-1-cyclohexen-1-yl)methyl]-, (R)-; Lavanduquinocine. CAS No. 167114-85-4. Molecular formula: C26H31NO3. Mole weight: 405.53. | |
| Lavendamycin | It is produced by the strain of Str. lavendulae C-22030. It's a quinone antibiotic. It has anti-bacterial and fungal effect, but the anti-bacterial effect is weaker than Streptonigrin, while the anti-fungal effect is stronger than Streptonigrin. Alternative Names: 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl-; Antibiotic K 82A. CAS No. 81645-09-2. Molecular formula: C22H14N4O4. Mole weight: 398.38. | |
| Lavendomycin | It is produced by the strain of Str. lavendulae subsp. brasillicus. It has strong activity against Staphylococcus aureus, Staphylococcus epidermococcus and Streptococcus faecalis with ED50 (mg/kg) of 2.33, 1.68 and 13.2, respectively (In vivo test in mice, abdominal infection, subcutaneous administration). It has no anti-gram-negative bacteria and fungi activity. Alternative Names: Antibiotic FR 900201; ((Z)-2-((S)-1-((S)-1-((2S,3R)-3-amino-2-((2S,3R)-2-amino-5-guanidino-3-methylpentanamido)butanoyl)piperidine-2-carbonyl)pyrrolidine-2-carboxamido)but-2-enoyl)-L-serine. Grades: ≥95%. CAS No. 82987-09-5. Molecular formula: C29H50N10O8. Mole weight: 666.78. | |
| Lavendustin A | Lavendustin A is an epidermal growth factor receptor inhibitor tyrosine kinase with IC50 value of 11 nM. Alternative Names: Lavendustin A; RG 14355; RG-14355; RG14355; 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid. Grades: ≥98% by HPLC. CAS No. 125697-92-9. Molecular formula: C21H19NO6. Mole weight: 381.38. | |
| L-Cysteinamide | L-Cysteinamide. CAS No. 74401-72-2. Molecular formula: C3H8N2OS. Mole weight: 120.2. | |
| L-Cysteinol | L-Cysteinol. CAS No. 125509-78-6. Molecular formula: C3H9NOS. Mole weight: 107.2. | |
| Lecideoidin | It is the depsidone isolated from a Lecidea sp. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,9-dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-, methyl ester; 2,9-Dichloro-3,8-dihydroxy-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid methyl ester. CAS No. 72458-10-7. Molecular formula: C17H12Cl2O7. Mole weight: 399.18. | |
| Lenoremycin | It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Alternative Names: Antibiotic A-130A; A-130A; Antibiotic Ro 21 6150; Dianemycin, 10-demethyl-19-de[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, [11(2R,5S,6R),12R]-; 6-Nonenoic acid, 8-[2,4',10,10'-tetramethyl-2'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7'-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, [2S-[2a[2'S*,4'R*,5'S*,7'S*[2R*,5S*,7R*(2R*,4S*,6E,8R*),9S*(2S*,5R*,6S*),10S*],10'S*],3b,5b,6b]]-. CAS No. 51257-84-2. Molecular formula: C47H78O13. Mole weight: 851.11. | |
| Lenoremycin sodium | It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Alternative Names: Antibiotic A130 sodium salt; Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, monosodium salt, (11(2R,5S,6R),12R)-; Antibiotic A-130A Sodium salt. CAS No. 58399-44-3. Molecular formula: C47H77NaO13. Mole weight: 873.10. | |
| Leprapinic acid | Leprapinic acid is a member of methoxybenzenes. Alternative Names: Leprapic acid; methyl (E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-(2-methoxyphenyl)acetate; Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (E)-; α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester; Benzeneacetic acid, α-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (αE)-; [3-Hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-(2-methoxy-phenyl)-acetic acid methyl ester. CAS No. 481-59-4. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Leprapinic acid methyl ether | Leprapinic acid methyl ether. Alternative Names: Benzeneacetic acid, 2-methoxy-α-(3-methoxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester, (E)-. CAS No. 22628-25-7. Molecular formula: C21H18O6. Mole weight: 366.36. | |
| Lepraric acid | 2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Alternative Names: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33. | |
| Leprolomin | It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Alternative Names: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grades: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38. | |
| Leptocillin | Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Alternative Names: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34. | |
| Leptofuranin A | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72. | |
| Leptofuranin B | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75. | |
| Leptofuranin C | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70. | |
| Leptofuranin D | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73. | |
| Leptolstatin | It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Alternative Names: 2H-Pyran-2-one, 6-[(1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxo-1,3,7,9,17-nonadecapentaen-1-yl]-5,6-dihydro-, (6R)-; (R)-6-((1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxononadeca-1,3,7,9,17-pentaen-1-yl)-5,6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69. | |
| Leptomycin A | a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Alternative Names: Leptomycin A;Jildamycin;87081-36-5;(2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid;NSC 369326;NSC369326;ATS1287 A, LMA;SCHEMBL14190847;MFCD01711669;BS-1083;NSC-369326;19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-;DA-54856;NS00011727;Leptomycin A; Antibiotic ATS 1287A; Antibiotic PD 118607; Jildamycin;(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid;2,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-. Grades: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C12H14N2O3S. Mole weight: 266.32. | |
| Leptomycin B | a potent anti-fungal antibiotic. Leptomycin B is an inhibitor of export protein CRM1. Alternative Names: 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; Elactocin; Mantuamycin; Antibiotic CI 940; PD 114720. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.73. | |
| Leptosin I | It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Alternative Names: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5ab,10ba,10cS*,15ab,18b,22ab,22ba,23aa,24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| Leptosin J | It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Alternative Names: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5aa,10bb,10cR*,15aa,18a,22aa,22bb,23ab,24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| Lestaurtinib | Lesraurtinib, also known as CEP701, KT 5555, SP 924, is an orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3. Alternative Names: CEP-701; KT-5555; SP 924; (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one. Grades: ≥98%. CAS No. 111358-88-4. Molecular formula: C26H21N3O4. Mole weight: 439.46. | |
| Leucanicidin | It is produced by the strain of Streptomyces. It is a potent nematocide and insecticide belonging to the bafilomycin class. It also has anti-fungal properties. Alternative Names: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one; 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-α-L-mannopyranosyl)-2-methoxy-24-methylhygrolidin. Grades: >95% by HPLC. CAS No. 91021-66-8. Molecular formula: C42H70O13. Mole weight: 783.00. | |
| Leucinostatin A | It is produced by the strain of Paecilomyces lilacinus A-267. It's a peptide antibiotic. It has a strong anti-pathogenic and non-pathogenic yeast and fungi activity, but also has a medium anti-bacterial effect. It was previously reported that Leucinostatin A and B mixtures inhibited HeLa cells. 0.05 μg/mL of Leucinostatin A for a week (0.25 mg/kg?d) has inhibitory effect on the airy ascites carcinoma entity type, and for ascites type is invalid. Alternative Names: Antibiotic 1907-VIII; Antibiotic CC 1014; Paecilotoxin A; Antibiotic P-168; beta-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-(2-(dimethylamino)-1-methylethyl)-, (1(S-(E)),9(S))-; Tryanocidin. Grades: >95% by HPLC. CAS No. 76600-38-9. Molecular formula: C62H111N11O13. Mole weight: 1218.61. | |
| Leucinostatin B | It is produced by the strain of Paecilomyces lilacinus A-267. It's a peptide antibiotic. It has a strong anti-pathogenic and non-pathogenic yeast and fungi activity, but also has a medium anti-bacterial effect. It was previously reported that Leucinostatin A and B mixtures inhibited HeLa cells. 0.05 μg/mL of Leucinostatin B for a week (0.25 mg/kg?d) has inhibitory effect on the airy ascites carcinoma entity type, and for ascites type is invalid. Alternative Names: Paecilotoxin B; Leucinostatin A, 9-[N-[1-methyl-2-(methylamino)ethyl]-b-alaninamide]-, [9(S)]-; Antibiotic 1907-II; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[1-methyl-2-(methylamino)ethyl]-, [1[S-(E)],9(S)]-. Grades: >95%. CAS No. 76663-52-0. Molecular formula: C61H109N11O13. Mole weight: 1204.58. | |
| Leucinostatin D | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. It has in vitro cytotoxic activity against HeLa 850, KB cells and sensitive leukemia cells P388 with ID50 of 1.00 ng/mL. Alternative Names: Paecilotoxin D; (4R)-N-[1-[[2-hydroxy-3-methyl-1-[2-[[3-methyl-1-[[3-methyl-1-[2-[2-[2-(1-methylaminopropan-2-ylcarbamoyl)ethylcarbamoyl]propan-2-ylcarbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]butyl]carbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]-3-methyl-butyl]-4-methyl-1-[(E,4S)-4-methylhex-2-enoyl]pyrrolidine-2-carboxamide. CAS No. 100334-47-2. Molecular formula: C56H101N11O11. Mole weight: 1104.47. | |
| Leucinostatin H | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Alternative Names: Paecilotoxin H; N-(1-(aminooxy)-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28-octaoxo-5,9,12,15,18,21,24,27-octaazadotriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide; Leucinostatin A, 2-L-leucine, N9-oxide. CAS No. 109539-58-4. Molecular formula: C57H103N11O12. Mole weight: 1134.49. | |
| Leucinostatin K | It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Alternative Names: Leucinostatin A, N9-oxide; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[2-(dimethylamino)-1-methylethyl]-, N9-oxide, [1[S-(E)],9(S)]-; N-(1-(aminooxy)-33-hydroxy-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28,35-nonaoxo-5,9,12,15,18,21,24,27-octaazaheptatriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide. CAS No. 109539-57-3. Molecular formula: C62H111N11O14. Mole weight: 1234.61. | |
| Leucomentin-5 | It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.11 μg/mL. The IC50 of reference Leucomentin-2 is 0.06 μg/mL. Molecular formula: C38H34O13. Mole weight: 698.67. | |
| Leucomentin-6 | It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.06 μg/mL. The IC50 of reference Leucomentin-4 is 0.11 μg/mL. Molecular formula: C42H38O13. Mole weight: 750.74. | |
| Leucomycin A1 | It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Alternative Names: 3-Deacetyljosamycin; Kitasamycin A1; Leucomycin V 4''-(3-methylbutanoate); LM-A1; Turimycin H-5; LeucoMycin V 4-isovalerate; 9-Dihydroniddamycin; 3-O-Deacetyljosamycin. Grades: >99% by HPLC. CAS No. 16846-34-7. Molecular formula: C40H67NO14. Mole weight: 785.96. | |
| Leucomycin A13 | It is a macrolide antibiotic produced by the strain of Str. kitasatoensis. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. Alternative Names: Kitasamycin A13; 4B-hexanoate leucomycin V; Leucomycin V 4''-hexanoate. Grades: >99% by HPLC. CAS No. 78897-52-6. Molecular formula: C41H69NO14. Mole weight: 799.98. | |
| Leucomycin A4 | It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Alternative Names: Leukomycin A4; Leucomycin V 3-acetate 4''-butanoate; KitasaMycin A4. Grades: >99% by HPLC. CAS No. 18361-46-1. Molecular formula: C41H67NO15. Mole weight: 813.97. | |
| Leucomycin A6 | Leucomycin A6 is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Alternative Names: YL-704B3; YL 704B3; YL 704 B3; Platenomycin-B3. CAS No. 18361-48-3. Molecular formula: C40H65NO15. Mole weight: 799.9. | |
| Leucomycin A9 | It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Alternative Names: Turimycin H2; Leucomycin V, 4B-acetate. CAS No. 18361-49-4. Molecular formula: C37H61NO14. Mole weight: 743.88. | |
| Leucomycin complex | Leucomycin complex is a family of closely related macrocyclic lactone antibiotics produced by streptomyces kitasatoensis. It is an animal health product for control of gram positive bacteria, gram negative cocci, leptospira and mycoplasma. Alternative Names: Kitasamycin A1; Turimycin H5; Leucomycin V 4-isovalerate. Grades: >95% by HPLC. CAS No. 1392-21-8. Molecular formula: C35H59NO13. Mole weight: 701.8. | |
| Leucomycin U | It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Alternative Names: Deisovaleryl josamycin; Deisovaleryl leucomycin A3; Leucomycin V 3-acetate; 4''-Deisovaleryljosamycin. CAS No. 31642-61-2. Molecular formula: C37H61NO14. Mole weight: 743.88. | |
| Leucomycin V | It is produced by the strain of Str. kitasatoensis. It's a macrolide antibiotic. It has strong anti-gram-positive bacterial effect, and also has an effect on spirochetes, rickettsium and Chlamydia. After the C3 position on the lactone ring in the structure is acetylated, the activity in vitro is reduced, but the activity in vivo is enhanced, and the toxicity is also reduced. The antibacterial activity of Leucomycin group A is stronger than group B. It has been used in clinical and the indications are the same as erythromycin. Alternative Names: Selectomycin; Turimycin; Antibiotic A 6599; Antibiotic JA-6599; Stereomycine; 4''-Deacylturimycin H; Deacylleucomycin A1; Deisovaleryl leucomycin A1. Grades: 97%. CAS No. 22875-15-6. Molecular formula: C35H59NO13. Mole weight: 701.84. | |
| Leucotylic acid | Leucotylic acid. Alternative Names: (3S,3aS,4S,5aR,5bR,7aR,8R,11aR,11bR,13aR,13bR)-4-hydroxy-3-(2-hydroxypropan-2-yl)-5a,5b,8,11a,13b-pentamethylicosahydro-1H-cyclopenta[a]chrysene-8-carboxylic acid; 16β,22-Dihydroxyhopan-23-oic acid; A'-Neogammaceran-23-oic acid, 16,22-dihydroxy-, (4α,16β)-; Leucotylinsaeure. CAS No. 5056-37-1. Molecular formula: C30H50O4. Mole weight: 474.72. | |
| Leucyl-threonine | Leucyl-threonine. Alternative Names: L-leucyl-L-threonine. CAS No. 38062-82-7. Molecular formula: C10H20N2O4. Mole weight: 232.28. | |
| Leuhistin | It is produced by the strain of Bacillus laterosporus BMI 156-14F1. It inhibits aminopeptidase M with IC50 of 0.2 μg/mL. It has no antimicrobial effects (100 μg/mL). Alternative Names: Leuhistine; (2R,3S)-2-((1H-imidazol-4-yl)methyl)-3-amino-2-hydroxy-5-methylhexanoic acid; 1H-Imidazole-4-propanoic acid, alpha-(1-amino-3-methylbutyl)-alpha-hydroxy-, (R-(R*,S*))-. Grades: 95%. CAS No. 129085-76-3. Molecular formula: C11H19N3O3. Mole weight: 241.29. | |
| Leuseramycin | It is produced by the strain of Str. hygroscopicus TM-531. It's a polyether antibiotic. It has anti-gram-positive bacteria, plant pathogenic bacteria and some protozoa effects. Alternative Names: (2R,4S,8R,E)-8-((2R,2'S,4'S,5R,5'S,7S,7'S,8S,9S,9'R,10'S)-9-hydroxy-2'-((2S,3S,5S,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)-9'-(((2R,5R,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,4',8,10'-tetramethyl-1,1',6,6'-tetraoxa[2,7'-bispiro[4.5]decan]-7-yl)-2,4,6-trimethyl-5-oxonon-6-enoic acid; 30-Deoxydianemycin; Antibiotic TM-531; TM-531. Grades: 95%. CAS No. 73537-10-7. Molecular formula: C47H78O13. Mole weight: 851.12. | |
| Levonorgestrel butyrate | Levonorgestrel butyrate is a butyl prodrug of levonorgestrel, a widely-used steroidal progestin. Alternative Names: 13-ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one butyrate; Levonorgestrel butanoate. CAS No. 86679-33-6. Molecular formula: C25H35O3. Mole weight: 383.54. | |
| Lexithromycin | It is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Alternative Names: Erythromycin A 9-methoxime; Wy 48314; Erythromycin A 9-(O-methyloxime); 9-deoxo-9-methoxyiminoerythromycin A; Azithromycin Impurity 4. Grades: >98% by HPLC. CAS No. 53066-26-5. Molecular formula: C38H70N2O13. Mole weight: 762.97. | |
| L-Glutamamide | L-Glutamamide. Alternative Names: Glutamamide; L-Glutamine amide. CAS No. 2013-17-4. Molecular formula: C5H11N3O2. Mole weight: 145.16. | |
| L-Glutamine methyl ester | L-Glutamine methyl ester. Alternative Names: (S)-Methyl 2,5-diamino-5-oxopentanoate. CAS No. 40846-98-8. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
| L-Glutaminol | L-Glutaminol. CAS No. 40217-15-0. Molecular formula: C5H12N2O2. Mole weight: 132.16. | |
| L-Glutamyl-L-Proline | L-Glutamyl-L-Proline is a dipeptide composed of glutamate and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Proline, L-a-glutamyl-; L-α-Glutamyl-L-proline; Glutamyl-proline; L-Proline, L-alpha-glutamyl-; Glu-Pro; glutamylproline; H-EP-OH. Grades: ≥98%. CAS No. 41745-47-5. Molecular formula: C10H16N2O5. Mole weight: 244.24. | |
| (-)-Licarin A | (-)-Licarin A is a natural product found in Magnolia dodecapetala and Magnolia kachirachirai. Alternative Names: Phenol, 4-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-2-methoxy-; 4-[(2R,3R)-2,3-Dihydro-7-methoxy-3-methyl-5-(1E)-1-propen-1-yl-2-benzofuranyl]-2-methoxyphenol; Phenol, 4-[(2R,3R)-2,3-dihydro-7-methoxy-3-methyl-5-(1E)-1-propenyl-2-benzofuranyl]-2-methoxy-; 2,3-(2R,3R)-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-5-(E)-propenylbenzofuran; Licarin A; NSC 370989. Grades: >98%. CAS No. 51020-86-1. Molecular formula: C20H22O4. Mole weight: 326.39. | |
| Lichexanthone | Lichexanthone is separated from the bark of Cupania cinerea. It has a role as a plant metabolite. CAS No. 15222-53-4. Molecular formula: C16H14O5. Mole weight: 286.28. | |
| Licoisoflavone A | Licoisoflavone A, a potential MRP inhibitor, is a natural flavonoid derived from the roots of Glycyrrhiza uralensis Fisch. It inhibits lipid peroxidation with an IC50 of 7.2 μM. Licoisoflavone A and Licoisoflavone B inhibit copper-induced protein oxidative modification of mice brain homogenate in vitro. Alternative Names: 2',4',5,7-Tetrahydroxy-3'-(3,3-dimethylallyl)isoflavone; 3-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one; Phaseoluteone; 4H-1-Benzopyran-4-one, 3-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-; 2',4',5,7-Tetrahydroxy-3'-(3,3-dimethylallyl)isoflavone; 3'-Isopentenyl-2',4',5,7-tetrahydroxyisoflavone. Grades: >95%. CAS No. 66056-19-7. Molecular formula: C20H18O6. Mole weight: 354.35. | |
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