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Spiro[4.5]decane-8-carboxylic acid, 7-hydroxy-1-(6-hydroxy-1,5-dimethylhexyl)-4-methyl-, methyl ester. Alternative Names: 7-Hydroxy-1-(6-hydroxy-1,5-dimethylhexyl)-4-methyl-spiro[4.5]decane-8-carboxylic acid methyl ester. CAS No. 90363-87-4. Molecular formula: C21H38O4. Mole weight: 354.52.
Spirobenzofuran
It is produced by the strain of Acremonium sp. HKI 0230. It has moderate activity against gram-positive bacteria such as Bacillus subtilis with MIC of 25 μg/mL. It has no effect against gram-negative bacteria and fungi. Alternative Names: 2,5-dihydroxy-2',2',6-trimethyl-2H-spiro[benzofuran-3,1'-cyclopentan]-4'-one. Molecular formula: C15H18O4. Mole weight: 262.30.
Spiro[cyclopentane-1,3'-[7]oxabicyclo[4.1.0]heptane]-2-butanoic acid, 5'-hydroxy-6'-(methoxycarbonyl)-γ,5-dimethyl-, methyl ester. Alternative Names: 5'-hydroxy-6'-(methoxycarbonyl)-γ,5-dimethyl-spiro[cyclopentane-1,3'-[7]oxabicyclo[4.1.0]heptane]-2-butanoic acid methyl ester. CAS No. 90363-76-1. Molecular formula: C19H30O6. Mole weight: 354.44.
Spirofungin A
It is produced by the strain of Str. violaceusniger Tü 4113. It has strong anti-yeast activity and moderate anti-filamentous fungus effect, but it has no effect against Gram-positive and Gram-negative bacteria. Alternative Names: (2E,6E,8E)-(4S,5S)-10-[(2R,3S,6S,8R,9S)-8-((1E,3E)-4-Carboxy-3-methyl-buta-1,3-dienyl)-3,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-deca-2,6,8-trienoic acid; (-)-spirofungin A; 2,6,8-Decatrienoic acid, 10-[(2R,3S,6S,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-, (2E,4S,5S,6E,8E)-. CAS No. 214143-44-9. Molecular formula: C29H42O7. Mole weight: 502.64.
Spirofungin B
It is produced by the strain of Str. violaceusniger Tü 4113. It has strong anti-yeast activity and moderate anti-filamentous fungus effect, but it has no effect against Gram-positive and Gram-negative bacteria. Alternative Names: (2E,6E,8E)-(4S,5S)-10-{(2R,3S,6R,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-buta-1,3-dienyl]-3,9-dimethyl-1,7-dioxa-spiro(5.5)undec-2-yl}-5-hydroxy-4,8-dimethyl-deca-2,6,8-trienoic acid; 2,6,8-Decatrienoic acid, 10-[(2R,3S,6R,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-, (2E,4S,5S,6E,8E)-. CAS No. 214143-46-1. Molecular formula: C29H42O7. Mole weight: 502.64.
Spirolaxine
Spirolaxine is a long-chain phthalide antibiotic produced by Sporotrichum laxum. It exhibits anti-Helicobacter pylori property. Alternative Names: (+)-spirolaxine; Spirolaxin; (3R)-5-Hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]dec-7-yl]pentyl]-1(3H)-isobenzofuranone. Grades: ≥95%. CAS No. 126382-01-2. Molecular formula: C23H32O6. Mole weight: 404.50.
Spiromesifen Metabolite M01
It is the metabolite of Spiromesifen, which is a spirocyclic tetronic acid, environmentally friendly and novel structural pesticide. Alternative Names: 1-Oxaspiro[4.4]non-3-en-2-one, 4-hydroxy-3-(2,4,6-trimethylphenyl)-; 3-Mesityl-2-oxo-1-oxaspiro(4.4)non-3-en-4-ol; Spiromesifen-alcohol; 4-Hydroxy-3-mesityl-1-oxaspiro(4.4)non-3-en-2-one. Grades: ≥90%. CAS No. 148476-30-6. Molecular formula: C17H20O3. Mole weight: 272.34.
Spiro-Oxanthromicin A
Spiro-Oxanthromicin A is a polyketide first isolated from a soil-derived Streptomyces sp. Spiro-Oxanthromicin A inhibits mislocalisation of the oncogenic mutant K-Ras from the plasma membrane of intact Madin-Darby canine kidney (MDCK) cells. It inhibits Bacillus cereus but has no activity against HSV-1, Mycobacterium tuberculosis H37Ra and phytopathogenic fungi. Alternative Names: Oxanthromicin A, spiro; (±)-spiro-oxanthromicin A; 2',7'-dihydro-2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-spiro[anthracene-9(10H),3'-[3H]benz[de]anthracene]-3,9'-dicarboxylic acid; 2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-2',7'-dihydro-10H-spiro[anthracene-9,3'-benzo[de]anthracene]-3,9'-dicarboxylic acid. Grades: ≥95% by HPLC. CAS No. 1616622-10-6. Molecular formula: C36H26O10. Mole weight: 618.58.
Spirotryprostatin A
Spirotryprostatin A is an indole alkaloid found in Aspergillus fumigatus fungus, which exhibits anti-mitotic activity. Alternative Names: Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione, 1,5a,6,7,8,10a-hexahydro-6'-methoxy-3-(2-methyl-1-propenyl)-, (2S,3S,5aS,10aS)-; (2S,3S,5aS,10aS)-1,5a,6,7,8,10a-Hexahydro-6'-methoxy-3-(2-methyl-1-propen-1-yl)spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H),3'-[3H]indole]-2',5,10(1'H)-trione; (-)-Spirotryprostatin A; (3S,3'S,5'aS,10'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-3,5a,6,7,8,10a-hexahydro-1H-dipyrrolo[1,2-c:1',4'-f]pyrazine]-2,5',10'-trione. Grades: 98.0%. CAS No. 182234-25-9. Molecular formula: C22H25N3O4. Mole weight: 395.45.
Spirotryprostatin B
It is a mammalian cell cycle inhibitor produced by the strain of Aspergillus fumigatus. 12.5 μg/mL of Spirotryprostatin B can inhibit the G2/M phase of the cell cycle in tsFT210 cells. Alternative Names: (3S,3'S,5'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-5a,6,7,8-tetrahydro-3H-dipyrrolo[1,2-c:1',3'-f]pyrazine]-2,5',10'-trione; Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H), 3'-[3H]indole]-2',5,10(1'H)-trione, 5a,6,7,8-tetrahydro-3-(2-methyl-1-propen-1-yl)-, (2S,3S,5aS)-. CAS No. 182234-26-0. Molecular formula: C21H21N3O3. Mole weight: 363.41.
Sporaricin A
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has the effect of anti-Gram-positive bacteria, Gram-negative bacteria and mycobacterium. The antibacterial activity of Sporaricin A is 8-60 times stronger than Sporaricin B. Alternative Names: 1-Epi-2-deoxyfortimicin A; 2-Amino-5-[(aminoacetyl)methylamino]-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-D-allo-inositol; Antibiotic KA 6606-I; D-allo-Inositol, 2-amino-5-[(aminoacetyl)methylamino]-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-. CAS No. 68743-79-3. Molecular formula: C17H35N5O5. Mole weight: 389.49.
Sporaricin B
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It mainly has the effect of anti-Gram-positive bacteria. The antibacterial activity of Sporaricin A is 8-60 times stronger than Sporaricin B. Alternative Names: Antibiotic KA 6606II; KA 6606II; D-allo-Inositol, 2-amino-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-4-O-methyl-5-(methylamino)-; 2-Amino-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-5-methylamino-2,3,5-trideoxy-D-allo-inositol; 2-Deoxyfortimycin B. CAS No. 68743-78-2. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sporaricin C
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has anti-bacterial and mycobacterium effects, and the antibacterial effect of Sporaricin C is twice as strong as Sporaricin D. Alternative Names: Antibiotic KA 6606III; KA-6606-III; D-allo-Inositol, 2-amino-5-((((aminocarbonyl)amino)acetyl)methylamino)-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-4-O-methyl-. CAS No. 68743-80-6. Molecular formula: C18H36N6O6. Mole weight: 432.52.
Sporaricin D
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has anti-bacterial and mycobacterium effects, and the antibacterial effect of Sporaricin C is twice as strong as Sporaricin D. Alternative Names: 2-Amino-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-5-[[(formylamino)acetyl]methylamino]-4-O-methyl-2,3,5-trideoxy-D-allo-inositol; Antibiotic KA-6606IV; D-allo-Inositol, 2-amino-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-5-[[(formylamino)acetyl]methylamino]-4-O-methyl-; KA-6606-IV. CAS No. 68743-81-7. Molecular formula: C18H35N5O6. Mole weight: 417.50.
Sporaricin E
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has a broad antimicrobial activity. Alternative Names: 2-deoxyfortimycin B; 4-Amino-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-1,4,5-trideoxy-L-chiro-inositol; Sporaricine E; L-chiro-Inositol, 4-amino-1,4,5-trideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-; Antibiotic KA 6606 VI; KA 6606-VI. CAS No. 71657-28-8. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sporaviridin
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. CAS No. 72497-34-8.
Sporaviridin A1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-A1; 16,35-Dioxabicyclo[29.3.1]pentatriaconta-11,19,21-trien-15-one, 3-[[O-3-amino-2,3,6-trideoxy-b-D-arabino-hexopyranosyl-(1(R)3)-O-[O-3-amino-2,3,6-trideoxy-b-D-arabino-hexopyranosyl-(1(R)3)-O-6-deoxy-b-D-glucopyranosyl-(1(R)4)]-O-[6-deoxy-b-D-glucopyranosyl-(1(R)2)]-6-deoxy-b-D-glucopyranosyl]oxy]-17-[14-[(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-lyxo-hexopyranosyl)oxy]-2,8,12-trihydroxy-7,9,13-trimethylpentadecyl]-14-ethyl-29-(b-D-glucopyranosyloxy)-1,7,9,13,23,25,27,33,34-nonahydroxy-4,18,24,30-tetrame. CAS No. 107021-77-2. Molecular formula: C100H179N3O41. Mole weight: 2079.48.
Sporaviridin A2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-A2; Sporaviridin A1, 2-deethyl-2-methyl-; 16,35-Dioxabicyclo[29.3.1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-78-3. Molecular formula: C99H177N3O41. Mole weight: 2065.45.
Sporaviridin B1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-B1; Sporaviridin A1, 4D-amino-4D-deoxy-; 16,35-Dioxabicyclo[29.3.1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-79-4. Molecular formula: C100H180N4O40. Mole weight: 2078.49.
Sporaviridin B2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-B2; Sporaviridin A1, 4D-amino-2-deethyl-4D-deoxy-2-methyl-; 16,35-Dioxabicyclo[29.3.1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-83-0. Molecular formula: C99H178N4O40. Mole weight: 2064.47.
Sporaviridin C1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-C1; Sporaviridin A1, 6D-hydroxy-; 16,35-Dioxabicyclo[29.3.1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-82-9. Molecular formula: C100H179N3O42. Mole weight: 2095.48.
Sporaviridin C2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Alternative Names: SVD-C2; Sporaviridin A1, 2-deethyl-6D-hydroxy-2-methyl-; 16,35-Dioxabicyclo[29.3.1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-81-8. Molecular formula: C99H177N3O42. Mole weight: 2081.45.
Sporeamicin A
It is a macrolide antibiotic produced by the strain of Saccaropolyspora sp. L53-18. It has anti-Gram-positive bacteria effect, but no anti-Gram-negative bacteria effect. It has cross-resistance with macrolide antibiotics. Alternative Names: Erythromycin, 9,10-didehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxo-; Antibiotic L 53-18A; SRM-A. Grades: ≥95%. CAS No. 131418-65-0. Molecular formula: C37H63NO12. Mole weight: 713.90.
Sporeamicin B
It is a macrolide antibiotic produced by the strain of Saccaropolyspora sp. L53-18. It has anti-Gram-positive bacteria effect, but no anti-Gram-negative bacteria effect. It has cross-resistance with macrolide antibiotics. Alternative Names: Erythromycin, 9,10-didehydro-3''-O-demethyl-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxo-; 9,10-Didehydro-3'-O-demethyl-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxoerythromycin; Antibiotic L 53-18B. Grades: ≥95%. CAS No. 143313-36-4. Molecular formula: C36H61NO12. Mole weight: 699.87.
Sporeamicin C
It is a macrolide antibiotic produced by the strain of Saccaropolyspora sp. L53-18. It has anti-Gram-positive bacteria effect, but no anti-Gram-negative bacteria effect. It has cross-resistance with macrolide antibiotics. Alternative Names: Erythromycin, 9,10-didehydro-N-demethyl-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxo-; N-Demethyl-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxo-9,10-didehydroerythromycin; Antibiotic L 53-18C. Grades: ≥95%. CAS No. 141340-34-3. Molecular formula: C36H61NO12. Mole weight: 699.87.
Sporidesmin A
It is produced by the strain of Pithomyces chartarum S-73a. It is cytotoxic to HeLa cells at a dose of 1 μg/mL. Alternative Names: Sporidesmin; Hydroxysporidesmin B; 3,11a-Epidithio-11aH-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-dione, 9-chloro-2,3,5a,6,10b,11-hexahydro-10b,11-dihydroxy-7,8-dimethoxy-2,3,6-trimethyl-, (3-alpha,5a-alpha,10b-alpha,11-beta,11a-alpha)-. CAS No. 1456-55-9. Molecular formula: C18H20ClN3O6S2. Mole weight: 473.95.
Sporidesmin E
It is produced by the strain of Pithomyces chartarum S-73a. It is cytotoxic to HeLa cells at a dose of 0.1 μg/mL. Alternative Names: (4R,6aR,11bS,12R,12aR)-10-chloro-11b,12-dihydroxy-8,9-dimethoxy-4,7,14-trimethyl-6a,7,11b,12-tetrahydro-4,12a-(epiminomethano)[1,2,3,5]trithiazepino[5',4':1,5]pyrrolo[2,3-b]indole-5,13(4H)-dione. CAS No. 22327-77-1. Molecular formula: C18H20ClN3O6S3. Mole weight: 506.02.
Sporidesmolide complex
It is a family of five closely related cyclic depsipeptides. Sporidesmolide complex contains three dominant components, I, II and V, with less quantities of the more polar III and only traces of sporidesmolide IV. Grades: >95% by HPLC. CAS No. 11113-90-9. Molecular formula: C34H60N4O8 (for sporidesmolide II). Mole weight: 652.86 (for sporidesmolide II).
Sporidesmolide I
It is the most polar of N-methyl analogues belonging to the hexadepsipeptide sporidesmolide complex. It has no activity against a variety of bacteria and fungi. It is a depsipeptide originally isolated from S. bakeri. Alternative Names: Sporidesmolide 1; cyclo[(2S)-2-hydroxy-3-methylbutanoyl-D-valyl-D-leucyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-N-methyl-L-leucyl]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-valyl]; cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-Val]. Grades: >95% by HPLC. CAS No. 2900-38-1. Molecular formula: C33H58N4O8. Mole weight: 638.84.
Sporidesmolide II
It is the most abundant of N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclic depsipeptide originally isolated from P. chartarum. Alternative Names: cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; (3S,6S,9S,12R,15R,18S)-15-((S)-sec-butyl)-3,12-diisobutyl-6,9,18-triisopropyl-4-methyl-1,10-dioxa-4,7,13,16-tetraazacyclooctadecane-2,5,8,11,14,17-hexaone. Grades: >95% by HPLC. CAS No. 3200-75-7. Molecular formula: C34H60N4O8. Mole weight: 652.86.
Sporidesmolide III
It is the only non-N-methylated analogue of the hexadepsipeptide sporidesmolide complex. It is the demethyl analogue of sporidesmolide I. It is a cyclodepsipeptide originally isolated from P. chartarum. Alternative Names: Cyclo(3-methyl-L-2-hydroxybutanoyl-D-valyl-D-leucyl-3-methyl-L-2-hydroxybutanoyl-L-valyl-L-leucyl); cyclo[D-Leu-OVal-Val-Leu-OVal-D-Val]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-L-leucyl-N-oxa-L-valyl-D-valyl]. Grades: >95% by HPLC. CAS No. 1803-67-4. Molecular formula: C32H56N4O8. Mole weight: 624.81.
Sporidesmolide V
It is the most non-polar of the N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclodepsipeptide fungal metabolite originally isolated from Pithomyces chartarum. Alternative Names: cyclo[D-Leu-OLeu-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-leucyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; cyclo(D-alloisoleucyl-D-leucyl-4-methyl-L-2-hydroxypentanoyl-L-valyl-N-methyl-L-leucyl-3-methyl-L-2-hydroxybutanoyl). Grades: >95% by HPLC. CAS No. 127072-57-5. Molecular formula: C35H62N4O8. Mole weight: 666.89.
Sporostatin
It is produced by the strain of Sporormiella sp. M5032. It inhibits cAMP-PDE with ID50 of 41 μg/mL. 1000 μg/mL of Sporostatin has no effect on Gram-positive bacteria, Gram-negative bacteria and Candida albicans. Alternative Names: (+)-Sporostatin. Molecular formula: C14H14O5. Mole weight: 262.26.
Squalestatin B
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Alternative Names: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70.
Squalestatin C
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Alternative Names: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50.
SS-228Y is an antibiotic produced by Chainia Sp. It is active against gram-positive bacteria and Ehrlich's ascites carcinoma. Alternative Names: Antibiotic SS-228 Y; SS-228 Y. Grades: 95%. CAS No. 56257-16-0. Molecular formula: C19H14O6. Mole weight: 338.31.
SS-56C
SS-56C is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Alternative Names: SS-56 C. CAS No. 39471-55-1. Molecular formula: C19H35N3O14. Mole weight: 529.5.
SS-56D
SS-56D is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Alternative Names: SS-56 D. Molecular formula: C19H35N3O13. Mole weight: 513.49.
Stachartin A
Stachartin A is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Alternative Names: Stachybotrysin; 3-Buten-2-one, 4-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8'a-tetramethylspiro[benzofuran-2(3H), 1'(2'H)-naphthalen]-7-yl]-, (3E)-. Grades: 98.0%. CAS No. 1978388-54-3. Molecular formula: C26H36O5. Mole weight: 428.56.
Stachartin B
Stachartin B is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Alternative Names: Stachybotrylactone B; Spiro[benzo[2,1-b:3,4-c']difuran-2(8H),1'(2'H)-naphthalen]-8-one, 3,3',4',4'a,5',6,6',7',8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 1978388-55-4. Molecular formula: C23H30O5. Mole weight: 386.48.
Stachartin C
Stachartin C is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Alternative Names: Stachybotrylactone C. Grades: 98.0%. CAS No. 1978388-56-5. Molecular formula: C29H41NO6. Mole weight: 499.64.
Stachartin D
Stachartin D is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Alternative Names: Stachybotrylactone D. Grades: 97.0%. CAS No. 1978388-57-6. Molecular formula: C30H43NO6. Mole weight: 513.67.
Stachartin E
Stachartin E is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Alternative Names: Stachybotrylactone E. Grades: 98.0%. CAS No. 1978388-58-7. Molecular formula: C33H41NO6. Mole weight: 547.68.
Stachybocin A
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.3 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.3 X 10-5 and 7.9 X 10-6, respectively. Alternative Names: Spirodihydrobenzofuranlactam ?; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'S*)],2'a,4'aa,6'a,8'ab]]-; AM 6222A. CAS No. 158827-60-2. Molecular formula: C52H70N2O10. Mole weight: 883.12.
Stachybocin B
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.8 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.2 X 10-5 and 9.5 X 10-6, respectively. Alternative Names: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'S,7'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'S*)],2'a,4'aa,6'a,7'a,8'ab]]-; AM 6222B. CAS No. 158827-61-3. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybocin C
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.9 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.5 X 10-5 and 9.4 X 10-6, respectively. Alternative Names: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'S,7'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*,2'R*,4'aS*,6'R*,8'aS*)],2'a,4'aa,6'a,7'a,8'ab]]-; AM 6222C. CAS No. 158827-62-4. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybotramide
Stachybotramide is produced by the mycelia and culture broth of Stachybotrys sp. Stachybotramide can stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). Alternative Names: Spirodihydrobenzofuranlactam II; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; Stachybotrin; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, [1'R-(1'α,2'α,4'aα,6'α,8'aβ)]-. Grades: 97.5%. CAS No. 149598-71-0. Molecular formula: C25H35NO5. Mole weight: 429.55.
Stachybotrin A
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. CAS No. 144373-26-2. Molecular formula: C23H31NO5. Mole weight: 401.49.
Stachybotrin B
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. Alternative Names: (+)-Stachybotrin B. CAS No. 144385-02-4. Molecular formula: C23H31NO4. Mole weight: 385.50.
Stachybotrin C
It is a neuritogenic agent produced by the strain of Stachyborrys parvispora F4708. It promotes the enlargement of the neural sinus of P12 cells, and the effect of Stachybotrin C is obvious, but the effect of Parvisporin is weak. Alternative Names: Pyrano[2,3-e]isoindol-7(2H)-one, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, (2R,3R)-rel-; Pyrano[2,3-e]isoindol-7(2H)-one, 2-(4,8-dimethyl-3,7-nonadienyl)-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, [2a(E),3a]-; Antibiotic NG 245. CAS No. 150351-23-8. Molecular formula: C31H39NO5. Mole weight: 505.64.
Stachybotrolide
Stachybotrolide is produced by Stachybotrys alternans. Alternative Names: Stachybotrylactone; (2R,2'R,4a'S,6'R,8a'S)-4,6'-dihydroxy-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzo[2,1-b:3,4-c']difuran-2,1'-naphthalen]-6(8H)-one; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, [1'R-(1'α,2'α,4'aα,6'α,8'aβ)]-; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 149691-31-6. Molecular formula: C23H30O5. Mole weight: 386.48.
Stachybotrylactam
An unusual spirodihydrobenzofuranlactam mycotoxin isolated from Stachybotrys sp. It shows immunosuppressant and weak HIV protease activity and shows diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition. Alternative Names: Stachybotrylactam;163391-76-2;3,4'-dihydroxy-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-7,8-dihydro-3H-furo[2,3-e]isoindole]-6'-one;Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-;CID 45934402;Compound NP-020819;DTXSID70672955;CHEBI:201797;AKOS040737949;J-010041;(3R,4aS,7R,8R,8aS)-3,4'-dihydroxy-4,4,7,8a-tetramethylspiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-7,8-dihydro-3H-uro[2,3-e]isoindole]-6'-one;4,6'-DIHYDROXY-2',5',5',8'A-TETRAMETHYL-3',4',4'A,6',7,7',8,8'-OCTAHYDRO-2'H,3H-SPIRO[FURO[2,3-E]ISOINDOLE-2,1'-NAPHTHALEN]-6-ONE. Grades: >95% by HPLC. CAS No. 163391-76-2. Molecular formula: C23H31NO4. Mole weight: 385.50.
Stambomycin A
Stambomycin A is a macrolide antibiotic with promising antitumor activity. CAS No. 1263082-06-9. Molecular formula: C73H133NO22. Mole weight: 1376.8.
Standard Solution Aflatoxin Mixture
The acetonitrile solution of 0.5 ppm for each of four mixed Aflatoxin species: Aflatoxin B1, Aflatoxin B2, Aflatoxin G1 and Aflatoxin G2, could be commonly used as a standard solution.
Standard Solution Fumonisin B1,B2 mixture
The 50ppm for each acetonitrile-water 1:1 solution of Fumonisin B1 and Fumonisin B2, could be used as a standard solution. Molecular formula: C34H59NO15.C34H59NO14. Mole weight: 1427.66.
Standard Solution Nivalenol
Nivalenol is a trichothecene mycotoxin isolated from Fusarium. CAS No. 23282-20-4. Molecular formula: C15H20O7. Mole weight: 312.31.
Staphcoccomycin
Staphcoccomycin is a macrolide antibiotic produced by Str. sp AS-NG-16. Activity against gram-positive bacteria. Alternative Names: Desmycarosyl-angolamycin. Grades: >98%. CAS No. 73047-31-1. Molecular formula: C39H65NO14. Mole weight: 771.93.
Staplabin
Staplabin is a substance produced by the fungus Stachybotrys microspora IFO 30018. Staplabin has the effect of stimulating the binding of plasminogen to fibrin and U937 cells. CAS No. 183006-79-3. Molecular formula: C28H39NO6. Mole weight: 485.61.
STAT5-IN-1
STAT5-IN-1, a cell-permeable nonpeptidic nicotinoyl hydrazone compound, is a selective STAT5 inhibitor with an IC50 of 47 μM for STAT5β isoform with much less effect towards the SH2 domain of STAT1, STAT3, or Lck (IC50>500 μM). Alternative Names: MDK-6314; STAT5 Inhibitor; STAT5Inhibitor; STAT5-Inhibitor; MDK 6314; MDK6314. N-[(E)-(4-oxochromen-3-yl)methylideneamino]pyridine-3-carboxamide; STAT5 Inhibitor. CAS No. 285986-31-4. Molecular formula: C16H11N3O3. Mole weight: 293.28.
Stauprimide
It is produced by the strain of Streptomyces. Stauprimide is an enhancer of embryonic stem cell differentiation into endoderm. It inhibits nuclear translocation of NME2. Alternative Names: N-Benzoyl-7-oxostaurosporine; N-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methylbenzamide; [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide. Grades: >98%. CAS No. 154589-96-5. Molecular formula: C35H28N4O5. Mole weight: 584.62.
Steffimycin
Steffimycin is an anthracycline antibiotic produced by Str. steffisburgensis var. steffisburgensis NRRL 3193. Activity against Gram-positive bacteria and fungi. Alternative Names: Steffimycin A. Grades: >98%. CAS No. 11033-34-4. Molecular formula: C28H30O13. Mole weight: 574.53.
Steffimycin B
Steffimycin B is an anthracycline antibiotic produced by Str. steffisburgensis var. steffisburgensis NRRL 3193. Activity against gram-positive bacteria. Alternative Names: 1,6,11(2H)-Naphthacenetrione, 4-((6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)oxy)-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-. Grades: >98%. CAS No. 54526-94-2. Molecular formula: C29H32O13. Mole weight: 588.56.
Stendomycin
Stendomycin is an ester peptide antibiotic complex produced by Str. sp. It has anti-gram-positive bacteria, mycobacteria and fungi activity. CAS No. 11006-78-3. Molecular formula: C79H137N17O19. Mole weight: 1629.03.
Stenosporonic acid
Stenosporonic acid. Alternative Names: ACMC-20m6dj; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-6-pentyl-1-propyl-; 8-Hydroxy-3-methoxy-11-oxo-6-pentyl-1-propyl-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. CAS No. 103538-04-1. Molecular formula: C23H26O7. Mole weight: 414.45.
Sterigmatocystin
Sterigmatocystin is a mycotoxin produced by several species of aspergillus. It is structurally related to the aflatoxins. It is mutagenic, teratogenic and carcinogenic and is less widespread and potent than Aflatoxin. It inhibits acyl-CoA. It is a cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme. Alternative Names: (3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; (3aR-cis)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; NSC 201423; NSC 204985; Sterigmatocystine. Grades: >95% by HPLC. CAS No. 10048-13-2. Molecular formula: C18H12O6. Mole weight: 324.28.
Stigmasterol glucoside
Stigmasterol glucoside is isolated from the herbs of Perilla frutescens (L.) Britt. Uses: Anticancer agent. Alternative Names: poriferasterol monoglucoside; stigmasterol 3-O-beta-D-glucoside; Prosaponin; Stigmasterol 3-glucoside; 3-O-beta-D-glucopyranosylstigmasterol; Stigmasta-5,22-dien-3-O-beta-D-glucopyranoside; (3beta,22E)-stigmasta-5,22-dien-3-yl beta-D-glucopyranoside. Grades: 97%. CAS No. 19716-26-8. Molecular formula: C35H58O6. Mole weight: 574.83.