BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| TLR7/8 agonist 1 | TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. CAS No. 1258457-59-8. Molecular formula: C22H25N5. Mole weight: 359.5. |  |
| TLR7/8 agonist 1 dihydrochloride | TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It exhibits prominent immunostimulatory activities. Alternative Names: TLR7/8 agonist 1 hydrochloride. CAS No. 1620278-72-9. Molecular formula: C22H27Cl2N5. Mole weight: 432.4. | |
| TMC-135A | TMC-135A is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60 with IC50 values of 0.07, 0.88, 0.11, 0.20, 0.15 and 0.05 μmol/L, respectively. Alternative Names: TMC-135 A. Molecular formula: C39H49N3O8S. Mole weight: 719.9. | |
| TMC-135B | TMC-135B is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60. Alternative Names: TMC-135 B. Molecular formula: C39H49N3O8S. Mole weight: 719.9. | |
| TMC-154 | TMC-154 is an antibiotic produced by Gliocladium sp. TC 1282. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Alternative Names: TMC 154. Molecular formula: C41H72O14. Mole weight: 789. | |
| TMC-169 | TMC-169 is an antibiotic of the aspochalasin group produced by Aspergillus flavipes TC 1446. It has cytotoxicity. Alternative Names: TMC 169. Molecular formula: C24H35NO3. Mole weight: 385.5. | |
| TMC-171A | TMC-171A is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Alternative Names: TMC-171 A. Molecular formula: C41H72O15. Mole weight: 805. | |
| TMC-171B | TMC-171B is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Alternative Names: TMC-171 B. Molecular formula: C41H72O15. Mole weight: 805. | |
| TMC-171C | TMC-171C is a polyketide antibiotic produced by Gliocladium sp. TC 1304. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr. Alternative Names: TMC-171 C. Molecular formula: C41H72O15. Mole weight: 805. | |
| TMC-1A | TMC-1A is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Alternative Names: TMC-1 A. Molecular formula: C28H36N2O7. Mole weight: 512.6. | |
| TMC-1B | TMC-1B is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Alternative Names: TMC-1 B. Molecular formula: C28H36N2O7. Mole weight: 512.6. | |
| TMC-1C | TMC-1C is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Alternative Names: TMC-1 C. Molecular formula: C30H38N2O7. Mole weight: 538.6. | |
| TMC-1D | TMC-1D is a Manumycin-associated antibiotic produced by Streptomyces sp. A-230. It has activity against gram-positive bacteria and cytotoxicity to various cancer cells. Alternative Names: TMC-1 D. Molecular formula: C30H40N2O7. Mole weight: 540.6. | |
| TMC-256A1 | TMC-256A1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 25 μmol/L. Alternative Names: TMC-256 A1. CAS No. 3773-18-0. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| TMC-256C1 | TMC-256C1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 1.7 μmol/L. Alternative Names: TMC-256 C1. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| TMC-260 | TMC-260 is an inhibitor of IL-4 signal transduction produced by Acremonium kiliense Grütz TC 1703. It inhibited the IL-4 driven luciferase activity with IC50 values of 9 μmol/L. Alternative Names: TMC 260. Molecular formula: C17H27NO5. Mole weight: 325.4. | |
| TMC-264 | TMC-264 is a STAT6 activation inhibitor produced by Phoma sp. TC 1674. It suppressed expression of IL-4 driven luciferase and germline Cepsilon mRNA with IC50 values of 0.3 and 0.4 μmol/L, respectively, and inhibited tyrosine phosphorylation of STAT6 with an IC50 value of 1.6 μmol/L. Alternative Names: TMC 264. Molecular formula: C16H13ClO7. Mole weight: 352.72. | |
| TMC-2A | TMC-2A is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Alternative Names: TMC-2 A. Molecular formula: C28H34N4O9. Mole weight: 570.6. | |
| TMC-2B | TMC-2B is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Alternative Names: TMC-2 B. Molecular formula: C28H34N4O8. Mole weight: 554.6. | |
| TMC-2C | TMC-2C is a dipeptidyl peptidase IV (DPIV) inhibitor isolated from the fermentation broth of Aspergillus oryzae A374. It inhibited rat kidney DPIV with IC50 value of 8.1 μmol/L. Alternative Names: TMC-2 C. Molecular formula: C28H34N4O8. Mole weight: 554.6. | |
| TMC-34 | TMC-34 is an macrolide antifungal antibiotic produced by Streptomyces sp. A-3030. Alternative Names: TMC 34. Molecular formula: C54H93N3O17. Mole weight: 1056.3. | |
| TMC-49A | TMC-49A is a transcriptional up-regulator of low density lipoprotein receptor. It is produced by Streptomyces sp. AS1345. It enhanced the synthesis of LDL receptor in human hepatoma HepG2 cells as assessed by a receptor binding assay. Alternative Names: TMC-49 A; 2-phenylethyl n-butyl carbamate. Molecular formula: C13H19NO2. Mole weight: 221.29. | |
| TMC-52A | TMC-52A is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 13 nM. Alternative Names: TMC-52 A. Molecular formula: C20H30N4O6. Mole weight: 422.5. | |
| TMC-52B | TMC-52B is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 10 nM. Alternative Names: TMC-52 B. Molecular formula: C20H30N4O6. Mole weight: 422.5. | |
| TMC-52C | TMC-52C is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 10 nM. Alternative Names: TMC-52 C. Molecular formula: C20H30N4O5. Mole weight: 406.5. | |
| TMC-52D | TMC-52D is a cysteine proteinase inhibitor produced by Gliocladium sp. F-2665. It strongly inhibited cysteine proteinases, in particular, cathepsin L with IC50 value of 6 nM. Alternative Names: TMC-52 D. Molecular formula: C20H30N4O5. Mole weight: 406.5. | |
| TMC-66 | TMC-66 is a selective endothelin conversion enzyme (ECE) inhibitor isolated from the culture broth of Streptomyces sp. A5008. Alternative Names: TMC 66. Molecular formula: C29H21NO9. Mole weight: 527.5. | |
| TMC-69 | TMC-69 is an antitumor antibiotic isolated from the fermentation broth of a fungal strain Chrysosporium sp. TC 1068. It exhibited moderate in vitro cytotoxic activity. Alternative Names: TMC 69. Molecular formula: C26H31NO4. Mole weight: 421.5. | |
| TMC-86A | TMC-86A is a 20S proteasome inhibitor isolated from the fermentation broth of Streptomyces sp. A5008. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 5.1 and 3.7 μmol/L, respectively. Alternative Names: TMC-86 A. Molecular formula: C16H26N2O6. Mole weight: 342.39. | |
| TMC-86B | TMC-86B is a 20S proteasome inhibitor isolated from the fermentation broth of Streptomyces sp. A5008. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 1.1 and 31 μmol/L, respectively. Alternative Names: TMC-86 B. Molecular formula: C20H34N2O7. Mole weight: 414.5. | |
| TMC-89A | TMC-89A is a 20S proteasome inhibitor produced by streptomyces sp. TC 1087. It inhibited chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 of 1.1, 0.39 and 7.2 μmol/L, respectively. Alternative Names: TMC-89 A; N-[(2R)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-L-threoninamide. Molecular formula: C21H36N4O9. Mole weight: 488.5. | |
| TMC-89B | TMC-89B is a 20S proteasome inhibitor produced by streptomyces sp. TC 1087. It inhibited chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 of 1.1, 0.51 and 7.1 μmol/L, respectively. Alternative Names: TMC-89 B; N-[(2S)-3-amino-2-methyl-3-oxopropanoyl]-L-threonyl-N-{1-[2-(hydroxymethyl)oxiran-2-yl]-4-methyl-1-oxopentan-2-yl}-L-threoninamide. Molecular formula: C21H36N4O9. Mole weight: 488.5. | |
| TMC-95A | TMC-95A is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. It inhibited the chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome with IC50 values of 5.4nM, 200nM, and 60nM, respectively. Alternative Names: TMC-95 A. CAS No. 220666-21-7. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95B | TMC-95B is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. It inhibited the chymotrypsin-like (ChT-L), trypsin-like (T-L), and peptidylglutamyl-peptide hydrolyzing (PGPH) activities of 20S proteasome to the same extent as TMC-95A. Alternative Names: TMC-95 B. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95C | TMC-95C is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. Alternative Names: TMC-95 C. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-95D | TMC-95D is a proteasome inhibitor produced by Apiospora montagnei Sacc. TC 1093. Alternative Names: TMC-95 D. Molecular formula: C33H38N6O10. Mole weight: 678.7. | |
| TMC-96 | TMC-96 is a proteasome inhibitor produced by Saccharothrix sp. TC 1094. It inhibited the chymotrypsin-like and peptidylglutamyl-peptide hydrolyzing activities of 20S proteasome with IC50 values of 2.9 and 3.5 μmol/L, respectively. Alternative Names: TMC 96. Molecular formula: C18H32N2O6. Mole weight: 372.5. | |
| TNO155 | TNO155 is an inhibitor of protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11), with potential antineoplastic activity. Alternative Names: TNO-155; TNO 155. Grades: 98%. CAS No. 1801765-04-7. Molecular formula: C18H24ClN7OS. Mole weight: 421.948. | |
| Tofacitinib N-Oxide | Tofacitinib N-Oxide is an impurity of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Alternative Names: Tofacitib related impuritie 8; 1-Piperidinepropanenitrile, 4-methyl-3-(methyloxido-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-. Grades: ≥95%. CAS No. 2028267-73-2. Molecular formula: C16H20N6O2. Mole weight: 328.37. | |
| Tolypomycin R | Tolypomycin R is produced by the strain of Str. tolypophorus B2847. It has a broad-spectrum antimicrobial effect, which protects mice infected with gram-positive bacteria, and also has an inhibitory effect on vaccine virus. Alternative Names: B-2847-R; L-erythro-Hexopyranose, 2,3,4,6-tetradeoxy-4-((5,6,11,12,13,14,15,16,16a,17,17a,18,21,22-tetradecahydro-2,12,14,16,26-pentahydroxy-10-methoxy-3,6,11,13,15,20-hexamethyl-5,18,21-trioxo-10H-4,6-epoxy-1,23-methenobenzo(d)cycloprop(n)(1,9)oxaazacyclotetracosin-25-yl)amino)-, 12-acetate. Grades: >98%. CAS No. 33889-22-4. Molecular formula: C43H56N2O14. Mole weight: 824.91. | |
| Tolypomycin Y | Tolypomycin Y is produced by the strain of Str. tolypophorus B2847. It has a broad-spectrum antimicrobial effect, which protects mice infected with gram-positive bacteria, and also has an inhibitory effect on vaccine virus. Alternative Names: NSC-177383; Tolypromycin Y. Grades: 96%. CAS No. 23412-26-2. Molecular formula: C43H54N2O14. Mole weight: 822.89. | |
| Tomatine | Tomatine is a glycoalkaloid extracted from the fruits of Solanum lycopersicum. Alternative Names: Lycopersicin; (3β,5α,22β,25S)-Spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside; α-Tomatine; NSC 234440; NSC 9223; TiterMax tomatine; Tomatine vaccine adjuvant. Grades: >98%. CAS No. 17406-45-0. Molecular formula: C50H83NO21. Mole weight: 1034.19. | |
| Tomaymycin | It is originally isolated from Str. achromogenes var. tomaymyceticus A-2127. Tomaymycin is resistant to gram-positive bacteria and fungi, and has a weak effect on E. coli. Alternative Names: NSC 177499; 2-Ethylidene-1,2,3,10,11,11a-hexahydro-8-hydroxy-7,11-dimethoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one. CAS No. 35050-55-6. Molecular formula: C16H20N2O4. Mole weight: 304.34. | |
| Topiramate EP Impurity C | Topiramate EP Impurity C. CAS No. 106881-41-8. | |
| Topopyrone A | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 1.22 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone B | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone B selectively inhibits topoisomerase I with the IC50 of 0.15 ng/mL. It also has anti-Gram-positive bacteria activity and it has a strong inhibitory effect on herpes virus, especially varicella zoster virus (VZV). Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone C | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone C selectively inhibits topoisomerase I with the IC50 of 4.88 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topopyrone D | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 19.63 ng/mL. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topostatin | Topostatin is originally isolated from Thermomonos pora alba No. 1520. It has inhibitory effects on human tumor cells, and the IC50 of SNB-75 and SNB-78 were 0.4 μmol/L and 7 μmol/L, respectively. Molecular formula: C36H58N4O11S. Mole weight: 754.93. | |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Alternative Names: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. Grades: >98%. CAS No. 64032-49-1. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Torreyanic acid | Torreyanic acid is a dimer quinone obtained from the endophytic bacterium Pestalotiopsis microspora. Torreyanic acid is cytotoxic to tumor cells and is 5-10 times more effective in cell lines sensitive to protein kinase C agonists. CAS No. 176260-42-7. Molecular formula: C38H44O12. Mole weight: 692.75. | |
| TPU-0031-A | TPU-0031-A is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
| TPU-0031-B | TPU-0031-B is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6. | |
| TPU-0037A | TPU-0037A is a neurogenesis agent isolated from Streptomyces. Alternative Names: 30-Demethyllydicamycin. Grades: >95% by HPLC. CAS No. 485815-59-6. Molecular formula: C46H72N4O10. Mole weight: 841.08. | |
| TPU-0037B | TPU-0037B is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Alternative Names: TPU-0037 B. Molecular formula: C47H72N4O9. Mole weight: 837.09. | |
| TPU-0037C | A close structural analogue of lydicamycin produced by the marine actinomycete Streptomyces platensis. It has antibacterial activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is closely related to BU-4514N which is isolated from a strain of microtetraspora as a neuritogenic agent. Alternative Names: Antibiotic TPU-0037C; 8-Dehydroxy-30-demethyllydicamycin; (+)-2-[21-[1-[(2,5-Dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)carbonyl]-1,2,4a,5,6,7,8,8a-octahydro-5-hydroxy-1,3-dimethyl-2-naphthalenyl]-2,6,10,14,18-pentahydroxy-11,17,19-trimethyl-4,8,12,16-heneicosatetraen-1-yl]-1-pyrrolidinecarboximidamide. Grades: >95% by HPLC. CAS No. 485815-61-0. Molecular formula: C46H72N4O9. Mole weight: 825.09. | |
| TPU-0037D | TPU-0037D is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Alternative Names: TPU-0037 D. Molecular formula: C47H74N4O9. Mole weight: 839.11. | |
| Trametol | Trametol is produced from the culture medium of Bjerkandera sp. BOS55. Alternative Names: 1,2-Propanediol, 1-(3-chloro-4-methoxyphenyl)-, (1R,2S)-. Grades: ≥98%. CAS No. 169217-47-4. Molecular formula: C10H13ClO3. Mole weight: 216.66. | |
| trans-4-Hydroxymellein | It is produced by the strain of Apiospora camptospora and marine-derived Microsphaeropsis sp. H5-50. It is the constituent of Moringa oleifera (horseradish tree) and Septoria nodorum. Alternative Names: 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R,4S)-; (3R,4S)-hydroxymellein; (3R,4S)-4,8-dihydroxy-3-methylisochroman-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R-trans)-; (-)-trans-4-hydroxymellein. CAS No. 70287-70-6. Molecular formula: C10H10O4. Mole weight: 194.18. | |
| Transplatin | The less-active isomer of the DNA damanging, platinum antitumor drug cisplatin. Transplatin is used in the treatment of a variety of solid tumors. Transplatin's anti-tumor activity can be activated by light. Alternative Names: Trans-Dichlorodiamineplatinum(II); Azane; Cisplatin. CAS No. 14913-33-8. Molecular formula: Cl2H6N2Pt. Mole weight: 300.05. | |
| Trehalosamine | Trehalosamine is a carbohydrate antibiotic originally isolated from Str. sp. It has anti-gram-positive bacteria and Pseudomonas aeruginosa and mycobacterium action. Alternative Names: 2-Trehalosamine; 2-amino-2-deoxy-alpha-D-glucopyranosyl alpha-D-glucopyranoside; alpha-D-Glucopyranosyl 2-amino-2-deoxy-alpha-D-glucopyranoside. CAS No. 27208-79-3. Molecular formula: C12H23NO10. Mole weight: 341.31. | |
| Trestatin A | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin A has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Alternative Names: Ro 09-0183. CAS No. 71884-70-3. Molecular formula: C56H94N2O40. Mole weight: 1435.33. | |
| Trestatin B | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin B has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Alternative Names: Ro 09-0184; alpha-D-Glucopyranoside, alpha-D-glucopyranosyl O-4,6-dideoxy-4-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-D-glucopyranosyl-(1-4)-O-alpha-D-glucopyranosyl-(1-4)-O-alpha-D-glucopyranosyl-(1-4)-, (1S-(1-alpha,4-alpha,5-beta,6-alpha))-. CAS No. 71869-92-6. Molecular formula: C37H63NO28. Mole weight: 969.88. | |
| Trestatin C | It is produced by the strain of Str. dimorphogenes NR-320-OM7HB. Trestatin C has a strong inhibitory effect on pancreatic α-amylase, and also inhibits the α-amylase of Bacillus subtilis and Aspergillus oryzae. Alternative Names: Ro 09-0185. CAS No. 71892-68-7. Molecular formula: C75H125N3O52. Mole weight: 1900.78. | |
| Triacetylphloroglucinol | It is the most hydrophobic of a small molecular weight phenolic metabolite belonging to the phloroglucinol (1,3,5 trihydroxybenzene) family. It is produced by pseudomonas fluoresces and exhibits a broad range of biological activities. It is important for dereplication to eliminate leads due to high amounts of weakly potent actives. Alternative Names: Phloroglucinol 2,4,6-Triacetate; 2,4,6-Triacetyl-1,3,5-trihydroxybenzene; 2,4,6-Triacetylphloroglucinol; 1,1',1''-(2,4,6-Trihydroxybenzene-1,3,5-triyl)triethanone. Grades: >98% by HPLC. CAS No. 2161-87-7. Molecular formula: C12H12O6. Mole weight: 252.22. | |
| Triacsin C | Triacsin C, originally isolated from Streptomyces sp., is a polyunsaturated fatty acid derivative. It has been found to be an acyl-CoA synthetase inhibitor as well as an effective vasodilator. It selectively inhibits arachidonoyl-CoA synthetase in intact cells and the nonspecific acyl-CoA synthetase in cell sonicates, as well as inhibits neutrophil functions. Alternative Names: 2E,4E,7E-Undecatriene-1-triazene; WS 1228A; 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene. Grades: ≥95%. CAS No. 76896-80-5. Molecular formula: C11H17N3O. Mole weight: 207.30. | |
| Trichodermin | Trichodermin is a terpenoid antibiotic which has anti-fungal and protozoal effects. It is originally isolated from Trichoderma viride. Alternative Names: Trichoderonin; NSC 73846; 12,13-Epoxytrichothec-9-en-4-ol acetate; [(2S)-trimethylspiro[[?]-2,2'-oxirane]yl] acetate. Grades: 99%. CAS No. 4682-50-2. Molecular formula: C17H24O4. Mole weight: 292.37. | |
| Trichodimerol | BMS-182123 is a substance produced by Penicillum chrysogenum V39673 that can inhibit the production of Tumor necrosis factor (TNF-a). The IC50 of inhibiting lipopolysaccharide (LPS) induced TNF-a in murine macrophages and human monocytes were 600 ng/mL and 4.0 μg/mL, respectively. Alternative Names: BMS-182123. CAS No. 145174-90-9. Molecular formula: C28H32O8. Mole weight: 496.55. | |
| Trichodion | Trichodion is originally isolated from Trichosporiella sp. It inhibits the expression of secretion alkaline phosphatase (SEAP) Reporter gene mediated by IFN-V with IC50 of 5-10 μg/mL, and it also inhibits the expression of human IFN-α promoter-driven Luciferase Reporter gene with IC50 of 2.5-5μg/mL. Molecular formula: C12H14O5. Mole weight: 238.24. | |
| Trichostatin C | Trichostatin C can protect the more unstable N-OH group of trichostatin A. It has anti-fungal, protozoan and anti-tumor activity. Alternative Names: 145-A. Grades: >95% by HPLC. CAS No. 68676-88-0. Molecular formula: C23H32N2O8. Mole weight: 464.51. | |
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