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Verrucofortine
A diketopiperazine alkaloid derived from tryptophan and leucine. It is a fungal metabolite isolated from penicillium verrucosum. It exhibits no apparent toxicity in mice even at high doses in vivo. Alternative Names: Fructigenine B; Verrucosine; Verrucozine; (-)-Verrucofortine; (3S-(3alpha,5aalpha,10balpha,11abeta))-6-Acetyl-10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione; (3S,5aR,10bR,11aS)-6-acetyl-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 113706-21-1. Molecular formula: C24H31N3O3. Mole weight: 409.52.
Verruculogen
Verruculogen is a tremorgenic mycotoxin isolated from penicillium verruculosu. It can inhibit the K+ channel activated by ca2+, and is a cell cycle inhibitor that prevents M phase division. Alternative Names: TR 1 toxin. Grades: >95% by HPLC. CAS No. 12771-72-1. Molecular formula: C27H33N3O7. Mole weight: 511.57.
Versicolin
Versicolin is originally isolated from Asp. versicolor. It only has antibacterial effect on filamentous fungi, and has no inhibitory effect on yeast-like fungi and bacteria. Alternative Names: 2,3,6-Trihydroxytoluene; Toluene-2,3,6-triol; BRN 2249549; 1-methyl-2,3,6-trihydroxybenzene. CAS No. 4389-44-0. Molecular formula: C7H8O3. Mole weight: 140.14.
Versicolorin A
Versicolorin A is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Alternative Names: Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione; NSC 274542; (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione. Grades: 98%. CAS No. 6807-96-1. Molecular formula: C18H10O7. Mole weight: 338.27.
Versicolorin B
Versicolorin B is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Alternative Names: (3aS,12aR)-4,6,8-trihydroxy-2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione; Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 2,3,3a,12a-tetrahydro-4,6,8-trihydroxy-, cis-(+-)-. CAS No. 4331-22-0. Molecular formula: C18H12O7. Mole weight: 340.28.
Verticillin B
Verticillin B is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Alternative Names: (6S,6'S)-19-Deoxy-6,6'-dihydroxychetocin. CAS No. 52212-86-9. Molecular formula: C30H28N6O7S4. Mole weight: 712.84.
Verticillin C
Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Alternative Names: Verticillin C. Grades: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90.
Vertimycin
It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Alternative Names: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19.
Vertisporin
It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Alternative Names: Spiro[4H-3a,22-(epoxyethano)-10,12-methano-17H,18H-furo[2',3':10,11][1,6]dioxacyclohexadecino[3,4-d][1]benzopyran-11(12H),2'-oxirane]-8,20(5H,22aH)-dione,2,3,10,10a,13a,16-hexahydro-2,3-dihydroxy-10a,15-dimethyl-, (2R,2'S,3R,3aR,6Z,10R,10aS,12R,13aR,17aR,21E,21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59.
Verucopeptin
It is an antibiotic produced by the strain of Actinomadura verrucosospora Q886-2. It has weak antimicrobial effect and can prolong the survival time of mice transplanted with melanoma. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Alternative Names: 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide. Grades: 98%. CAS No. 138067-14-8. Molecular formula: C43H73N7O13. Mole weight: 896.08.
Vibralactone B
Vibralactone B is an antibacterial compound produced from liquid fermentations of Stereum hirsutum that inhibits the growth of E. coli and Pseudomonas aeruginosa. Alternative Names: (1beta)-2alpha-Prenyl-3beta-hydroxy-5beta-(hydroxymethyl)-6-oxabicyclo[3.1.0]hexane-2-carboxylic acid 2,3-lactone; 3,7-Dioxatricyclo[4.2.0.02,4]octan-8-one, 4-(hydroxymethyl)-1-(3-methyl-2-buten-1-yl)-, (1S,2R,4R,6S)-; (1S,2R*,3R*,5S)-2,3-epoxyvibralactone. Grades: ≥98%. CAS No. 1093230-95-5. Molecular formula: C12H16O4. Mole weight: 224.25.
Vibralactone D
Vibralactone D is isolated from Boreostereum vibrans and exhibits weak inhibitory effect against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD). Alternative Names: (1S,5R,6S)-6-hydroxy-5-(3-methylbut-2-enyl)-3-oxabicyclo[3.2.1]octan-4-one; 3-Oxabicyclo[3.2.1]octan-2-one, 7-hydroxy-1-(3-methyl-2-buten-1-yl)-, (1R,5S,7S)-. Grades: ≥98%. CAS No. 1251748-32-9. Molecular formula: C12H18O3. Mole weight: 210.27.
Vibralactone K
Vibralactone K is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Alternative Names: 1H-Cyclopenta[c]furan-1-one, hexahydro-6-hydroxy-5-(3-methyl-2-buten-1-yl)-, (3aS,5S,6R,6aR)-. Grades: ≥98%. CAS No. 1623786-66-2. Molecular formula: C12H18O3. Mole weight: 210.27.
Vibralactone L
Vibralactone L is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Alternative Names: 3-Furanpropanoic acid, 2,5-dihydro-α-(3-methyl-2-buten-1-yl)-5-oxo-, ethyl ester, (+)-. Grades: ≥98%. CAS No. 1623786-67-3. Molecular formula: C14H20O4. Mole weight: 252.31.
Vicanicin
Vicanicin is a depsidone isolated from the lichen Teloschistesflavicans (Sw.) Norm. Vicanicin can induce apoptosis of DU-145 and LNCaP cells. Alternative Names: 2,7-Dichloro-3-hydroxy-8-methoxy-1,4,6,9-tetramethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one. CAS No. 33211-22-2. Molecular formula: C18H16Cl2O5. Mole weight: 383.22.
Vicenistatin
It is a macrocyclic lipid antibiotic produced by the strain of Str. sp. HC34. In vitro it is cytotoxic to human leukemia HL-60 cells and human colon cancer Co-LO205 cells with IC50 (μg/mL) of 0.12 and 0.19, respectively. Alternative Names: Azacycloeicosa-3,5,10,13,15-pentaen-2-one, 7,11,13,19-tetramethyl-8-[[2,4,6-trideoxy-4-(methylamino)-β-D-ribo-hexopyranosyl]oxy]-, (3E,5E,7S,8S,10E,13E,15E,19S)-; Antibiotic HC34; NSC 641691; Vicenistatine. CAS No. 150999-05-6. Molecular formula: C30H48N2O4. Mole weight: 500.71.
Vicenistatin M
It is produced by the strain of Streptomyces sp. HC-34. It is a homologue of Mycarose replacing amino sugars in the Vicenstatin molecule, and it loses the cytotoxicity of Vicenstatin. Alternative Names: (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one; (3E,5E,10E,13E,15E)-(7S,8S,19S)-8-((2R,4S,5R,6R)-4,5-Dihydroxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-7,11,13,19-tetramethyl-azacycloicosa-3,5,10,13,15-pentaen-2-one; Vicenistatine M. CAS No. 312532-50-6. Molecular formula: C30H47NO5. Mole weight: 501.70.
Victoxinine
Victoxinine is a toxic metabolite of Helminthosporium victoriae. Alternative Names: (4aalpha,8aalpha)-Decahydro-8-methyl-9-methylene-5beta-isopropyl-4beta,8beta-methanoisoquinoline-2-Ethanol; Victoxinin; 4,8-Methanoisoquinoline-2(1H)-Ethanol, octahydro-8-methyl-9-methylene-5-(1-methylethyl)-, (4R,4aR,5R,8R,8aS)-rel-(+)-. Grades: ≥98%. CAS No. 39965-06-5. Molecular formula: C17H29NO. Mole weight: 263.42.
Vinblastine
Vinblastine, an inhibitor of nAChR, is a natural alkaloid isolated from the plant Vinca rosea Linn. It binds to tubulin and inhibits microtubule formation, leading to disruption of mitotic spindle assembly and arrest of tumor cells in the M-phase of the cell cycle. It may also interfere with the metabolism of amino acids, cyclic AMP, and glutathione. It is used to treat malignant lymphoma. Uses: Antitumor. Alternative Names: [3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-Methyl 4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate; 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid, 4-(acetyloxy)-3a-ethyl-9-(5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino(5,4-b)indol-9-yl)-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-, methyl ester, (3aR-(3aα,4β,5β,5aβ,9(3R*,5S*,7R*,9S*),10bR*,13aα))-; Rozevin; (+)-Vinblastine; Vincaleukoblastine. Grades: >98%. CAS No. 865-21-4. Molecular formula: C46H58N4O9. Mole weight: 810.97.
Vindolinine
Vindolinine is an alkaloid isolated from leaf extract (DA) of Catharanthus roseus (L.) G. Don. Alternative Names: (2alpha,3beta,5alpha,12beta,19alpha,20R)-6,7-Didehydro-2,20-cycloaspidospermidine-3-carbox ylic acid, methyl ester. Grades: 95%. CAS No. 5980-2-9. Molecular formula: C21H24N2O2. Mole weight: 336.435.
Vinetorin
Vinetorin is a xanthone compound. Alternative Names: Xanthen-9-one, 4-chloro-3,8-dihydroxy-6-methoxy-1-methyl- (8CI); 4-Chloro-3,8-dihydroxy-6-methoxy-1-methyl-9H-xanthen-9-one. CAS No. 23460-01-7. Molecular formula: C15H11ClO5. Mole weight: 306.7.
Vinylamycin
It is a depsipeptide antibiotic produced by the strain of Streptomyces sp. M1982-63F1. It has activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 1.56-3.13 μg/mL. Alternative Names: (8E,12S,15R)-3-(1-Methylheptyl)-4-(2-hydroxyethyl)-7-methylene-12-methyl-15-isopropyl-2-oxa-6,11,14-triazacyclopentadecane-8-ene-1,5,10,13-tetraone; 1-Oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone, 14-[1-(2-hydroxyethyl)-2-methyloctyl]-6-methyl-11-methylene-3-(1-methylethyl)-, (3R,6S,9E)-. CAS No. 224427-91-2. Molecular formula: C26H43N3O6. Mole weight: 493.64.
Violaceol II
It is a mycotoxin isolated from Emericella violacea and Aspergillus spp. It has weak activity against Gram-positive bacteria, Gram-negative bacteria, fungi and yeast. Alternative Names: violacerol-II; 3-(2,6-dihydroxy-4-methylphenoxy)-5-methylbenzene-1,2-diol; 5-methyl-2-[5-methyl-2,3-bis(oxidanyl)phenoxy]benzene-1,3-diol; 2-(2,3-dihydroxy-5-methyl-phenoxy)-5-methyl-resorcinol. CAS No. 81827-49-8. Molecular formula: C14H14O5. Mole weight: 262.26.
Viomycin
Tuberactinomycin B is a member of the tuberactinomycin family of antibiotics used for the treatment of multidrug-resistant tuberculosis. Tuberactinomycin B inhibits group I intron splicing and prokaryotic protein synthesis, and freezes bacterial ribosomes in either the pre-or post-translational state. Uses: The treatment of multidrug-resistant tuberculosis. Alternative Names: Tuberactinomycin B; Celiomycin; Florimycin; Viomicina; Viomycine; Viomycinum. CAS No. 32988-50-4. Molecular formula: C25H43N13O10. Mole weight: 685.69.
Viomycin sulfate
It is a peptide antibiotic produced by the strain of Str. puniceus 1314-5 and Str. floridae A5014. It has broad-spectrum antibacterial and strong anti-mycobacterium effect. 1-10 μg/mL of Viomycin can inhibit the growth of most tuberculosis bacilli, the main effect is to inhibit the protein synthesis of bacteria, but bacteria are prone to develop drug resistance. In clinical application, it is only used as a second-line drug to treat tuberculosis. Alternative Names: Tuberactinomycin B sulfate salt; celicomycin-sulfate; florimycin sulfate; Vinacetin A sulfate; hexanamide, 3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[[(aminocarbonyl)amino]methylene]-3-[(4R,6S)-2-amino-3,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadec-15-yl]-, (3S)-, sulfate (1:1) (salt). CAS No. 37883-00-4. Molecular formula: C25H43N13O10.H2O4S. Mole weight: 783.77.
Viomycin trihydrochloride
It is a peptide antibiotic produced by the strain of Str. puniceus 1314-5 and Str. floridae A5014. It has broad-spectrum antibacterial and strong anti-mycobacterium effect. 1-10 μg/mL of Viomycin can inhibit the growth of most tuberculosis bacilli, the main effect is to inhibit the protein synthesis of bacteria, but bacteria are prone to develop drug resistance. In clinical application, it is only used as a second-line drug to treat tuberculosis. Alternative Names: Florimycin trihydrochloride; Viomycinum trihydrochloride; Vinacetin A trihydrochloride; Hexanamide, 3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[[(aminocarbonyl)amino]methylene]-3-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,1 3-pentaazacyclohexadec-15-yl]-, (3S)-, hydrochloride (1:3). CAS No. 39750-31-7. Molecular formula: C25H43N13O10.3HCl. Mole weight: 795.07.
Vioxanthin
Vioxanthin is an antibiotic produced by Malbranchea pulchella var. sulfurea. It is active against gram-positive bacteria and bacteroides fragilis. Alternative Names: Tf-26Vx. CAS No. 15447-05-9. Molecular formula: C30H26O10. Mole weight: 546.5.
Viranamycin A
It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 5.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 6.4 ng/mL. Alternative Names: Concanamycin A, 23-O-(3-carboxy-1-oxo-2-propenyl)-23-O-de[4-O-(aminocarbonyl)-2,6-dideoxy-b-D-arabino-hexopyranosyl]-25-de(1-propenyl)-25-methyl-. CAS No. 139595-03-2. Molecular formula: C41H64O13. Mole weight: 764.94.
Viranamycin B
It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 2.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 1.9 ng/mL. Alternative Names: Concanamycin A, 25-de(1-propenyl)-25-methyl-. CAS No. 139595-04-3. Molecular formula: C44H73NO14. Mole weight: 840.05.
Virantmycin
It is produced by the strain of Str. nitrosporeus AM-2722. It has antiviral effect. It inhibits four RNA viruses and four DNA viruses with MIC (μg/mL) of 0.008-0.04 and 0.005-0.03, respectively. It has weak antifungal effect. Alternative Names: 6-Quinolinecarboxylic acid, 3-chloro-2-(3,4-dimethyl-3-penten-1-yl)-1,2,3,4-tetrahydro-2-(methoxymethyl)-, (2R,3R)-; NSC 374127; 6-Quinolinecarboxylic acid, 3-chloro-2-(3,4-dimethyl-3-pentenyl)-1,2,3,4-tetrahydro-2-(methoxymethyl)-, (2R-cis)-; (-)-Virantmycin. Grades: 99%. CAS No. 76417-04-4. Molecular formula: C19H26C1NO3. Mole weight: 351.87.
Virensic acid
It is a lichen acid with enzyme inhibitory potential. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-; 10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; Granulatine; NSC 685587. CAS No. 668-14-4. Molecular formula: C18H14O8. Mole weight: 358.30.
Viridicatin
It is a quinoline aromatic antibiotic produced by the strain of Pen. viridicatum, Pen. cyclopium SM-72 and Pen. puberulum. It has anti-gram-positive bacteria and mycobacteria effects. Alternative Names: 2,3-dihydroxy-4-phenylquinoline; 2(1H)-Quinolinone, 3-hydroxy-4-phenyl-. Grades: >99% by HPLC. CAS No. 129-24-8. Molecular formula: C15H11NO2. Mole weight: 237.25.
Viridicatol
Viridicatol is a fungal metabolite found in various Penicillium species as well as Phoma. It suppresses the expression of COX-2 and inducible nitric oxide synthase (iNOS) and inhibits production of nitric oxide and prostaglandin E2 (PGE2) in LPS-stimulated RAW 264.7 and BV2 cells. Alternative Names: 2(1H)-Quinolinone, 3-hydroxy-4-(3-hydroxyphenyl)-; Carbostyril, 3-hydroxy-4-(m-hydroxyphenyl)-; 3-hydroxy-4-(3-hydroxyphenyl)carbostyril; 4-(3-Hydroxyphenyl)-2,3-quinolinediol. Grades: ≥95%. CAS No. 14484-44-7. Molecular formula: C15H11NO3. Mole weight: 253.25.
Viridicatumtoxin
A tetracycline-like metabolite produced by several species of penicillium. It causes myocardial deterioration, renal tubule necrosis and spleen atrophy. It is a mycotoxin and a potent antibacterial with activity against S. Aureus including MRSA and QRSA strains. Alternative Names: NSC 159628; viridicatumtoxin A; (1R,7'aR,11'aR,12'R)-rel-(-)-7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide; (2'α,7'aβ,11'aβ,12'β)-(-)-7',7'a,8',11',11'a,12'-Hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide. Grades: >98% by HPLC. CAS No. 39277-41-3. Molecular formula: C30H31NO10. Mole weight: 565.57.
Viridin
It is a steroidal antibiotic produced by the strain of Gliocladium virens. It has anti-fungal and gram-positive bacterial effects. Alternative Names: (1S-(1alpha,2alpha,11balpha))-1,7,8,11b-Tetrahydro-1-hydroxy-2-methoxy-11b-methylcyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione; 18-Norandrosta-5,8,11,13-tetraeno(6,5,4-bc)furan-3,7,17-trione, 1-hydroxy-2-methoxy-, (1beta,2beta)-; Cyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione, 1,7,8,11b-tetrahydro-1-hydroxy-2-methoxy-11b-methyl-, (1S,2R,11bS)-. CAS No. 3306-52-3. Molecular formula: C20H16O6. Mole weight: 352.34.
Viridomycin F
It is a viridomycin antibiotic produced by the strain of Streptomyces sp. K96-0188. It has weak insecticidal and nematocidal activity. It also has weak activity against Piricularia oryzae and Acholeplasma laidlawii. Alternative Names: Antibiotic K 96-0188. CAS No. 221394-79-2. Molecular formula: C21H14N3O9Fe. Mole weight: 508.20.
Virustomycin A
Virustomycin A is a 18-membered macrolide antibiotic originally isolated from Streptomyces sp. AM-2604. It is effective against infectious and plant pathogenic fungi. It is active against trichomonads and various RNA and DNA viruses. Alternative Names: AM 2604A; Antibiotic AM 2604A; [2R-[2R*[1S*[2R*,4R*,5S*,6R*(E)],2R*,3S*],3S*,4E,6E,9R*,10S*,11S*,12R*,13R*,14E,16Z]]-2-[3-(11-Ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl)-2-hydroxy-1-methylbutyl]tetrahydro-2-hydroxy-5-methyl-6-(1-propenyl)-2H-pyran-4-yl Ester 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoic Acid; 23-O-De(4-O-aminocarbonyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-23-O-[4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-butenyl]concanamycin A. Grades: ≥98%. CAS No. 84777-85-5. Molecular formula: C48H71NO14. Mole weight: 886.08.
Vitamin E calcium succinate
Vitamin E calcium succinate. CAS No. 14638-18-7.
Vitexin 2''-O-p-coumarate
Vitexin 2''-O-p-coumarate is a compound of the flavonoid class isolated from the seeds of Trigonella foenum-graecum. Vitexin 2''-O-p-coumarate promotes 2BS cell proliferation induced by H(2)O(2). Alternative Names: [(2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 59282-55-2. Molecular formula: C30H26O12. Mole weight: 578.526.
WA8242A
WA8242A is a PLA2 inhibitor consisting of A1 and A2. It is produced by Steptomyces violaceusniger No. 8242. Alternative Names: WA-8242A. Molecular formula: C39H74N2O7. Mole weight: 683.
WA8242B
WA8242B is a PLA2 inhibitor produced by Steptomyces violaceusniger No. 8242. Alternative Names: WA-8242B. Molecular formula: C40H76N2O7. Mole weight: 697.
Waol A
It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.1 μg/mL. Alternative Names: FD-211; NSC726144; NSC-726144; 5H-Furo[3,4-b]pyran-5-one, 2,3,7,7a-tetrahydro-3-hydroxy-2,7-di-(1E)-1-propen-1-yl-, (2R,3R,7S,7aR)-. Molecular formula: C13H16O4. Mole weight: 236.26.
Waol B
It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.2 μg/mL. Alternative Names: FD-212; Propanoic acid, 3-[(2R,4S,5S)-dihydro-4-hydroxy-2,5-di-(1E)-1-propen-1-yl-3(2H)-furanylidene]-2-hydroxy-, methyl ester, (3E)-. Molecular formula: C14H20O5. Mole weight: 268.31.
Watasemycin A
It is produced by the strain of Streptomyces sp. TP-A0597. It has anti-staphylococcus aureus, bacillus subtilis, proteus bizarre and cryptococcus neoformans activity with MIC (μg/mL) of 12.5, 25.0, 0.39 and 20.0, respectively. Alternative Names: 4-Thiazolidinecarboxylic acid, 2-[(4R,5S)-4,5-dihydro-2-(2-hydroxyphenyl)-5-methyl-4-thiazolyl]-3,4-dimethyl-, (2S,4S)-. Molecular formula: C16H20N2O3S2. Mole weight: 352.47.
Watasemycin B
It is produced by the strain of Streptomyces sp. TP-A0597. It has anti-staphylococcus aureus, bacillus subtilis, proteus bizarre and cryptococcus neoformans activity, but its antibacterial activity is lower than Watasemycin A. Alternative Names: 4-Thiazolidinecarboxylic acid, 2-[(4R,5S)-4,5-dihydro-2-(2-hydroxyphenyl)-5-methyl-4-thiazolyl]-3,4-dimethyl-, (2R,4S)-. Molecular formula: C16H20N2O3S2. Mole weight: 352.47.
WB-3559A
WB-3559A is a fibrinolytic metabolite produced by Flavobacterium sp. Alternative Names: WB-3559 A; WB 3559 A. CAS No. 96053-97-3. Molecular formula: C36H66N2O7. Mole weight: 638.9.
WB-3559B
WB-3559B is a fibrinolytic metabolite produced by Flavobacterium sp. Alternative Names: WB-3559 B; WB 3559 B. CAS No. 96053-96-2. Molecular formula: C37H68N2O7. Mole weight: 652.9.
WB-3559C
WB-3559C is a fibrinolytic metabolite produced by Flavobacterium sp. Alternative Names: WB-3559 C; WB 3559 C. CAS No. 96095-05-5. Molecular formula: C36H68N2O7. Mole weight: 640.9.
WB-3559D
WB-3559D is a fibrinolytic metabolite produced by Flavobacterium sp. Alternative Names: WB-3559 D; WB 3559 D. CAS No. 96095-04-4. Molecular formula: C37H70N2O7. Mole weight: 655.
WF-10129
WF-10129 is an angiotensin converting enzyme (ACE) inhibitor produced by Doratomyces putredinis, with IC50 of 1.4 X 10(-8) M. Alternative Names: WF 10129. CAS No. 109075-64-1. Molecular formula: C20H28N2O8. Mole weight: 424.4.
WF11605
WF11605 is an antagonist of leukotriene B4 (LTB4) isolated from the fungal strain F11605. It inhibited LTB4-induced chemotaxis of rabbit polymorphonuclear leukocytes (PMNLs) with an IC50 value of 1.7 x 10(-7) M and blocked 3H-LTB4 binding to PMNL membranes at 5.6 x 10(-6) M (IC50). It also inhibited LTB4-induced degranulation of rabbit PMNLs at 3.0 x 10(-6) M (IC50). Alternative Names: WF 11605; WF-11605. CAS No. 127475-47-2. Molecular formula: C38H60O11. Mole weight: 692.9.
WF11899A
WF11899A is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Alternative Names: WF-11899A. Molecular formula: C51H82N8O21S. Mole weight: 1175.3.
WF11899B
WF11899B is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Alternative Names: WF-11899B. Molecular formula: C51H82N8O20S. Mole weight: 1159.3.
WF11899C
WF11899C is a lipopeptide antibiotic isolated from the culture broth of Coleophoma empetri F-11899. It shows antifungal activity against Candida spp. Alternative Names: WF-11899C. Molecular formula: C51H82N8O19S. Mole weight: 1143.3.
WF-1360B
WF-1360B is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Alternative Names: Antibiotic WF-1360B. Molecular formula: C34H45NO8. Mole weight: 595.72.
WF-1360C
WF-1360C is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Alternative Names: Antibiotic WF-1360C. Molecular formula: C34H45NO9. Mole weight: 611.72.
WF-1360E
WF-1360E is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Alternative Names: Antibiotic WF-1360E. Molecular formula: C37H53NO9. Mole weight: 655.82.
WF-1360F
WF-1360F is one component of Rhizoxin complex produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Alternative Names: Antibiotic WF-1360F. Molecular formula: C35H47NO8. Mole weight: 609.75.
WF14861
WF14861 is a cathepsins B and L inhibitor obtained from the culture mycelium of a fungus strain Colletotrichum sp. No. 14861. Alternative Names: WF 14861; WF-14861. Molecular formula: C20H30N4O6. Mole weight: 422.5.
WF14865A
WF14865A is a cathepsins B and L inhibitor with IC50 of 8.4 X 10(-9) and 6.6 X 10(-8) mol/L, respectively. It is produced by Aphanoascus fulvescens. Alternative Names: WF-14865A. Molecular formula: C16H25N5O5. Mole weight: 367.4.
WF14865B
WF14865B is a cathepsins B and L inhibitor with IC50 of 1.3 X 10(-8) and 7.2 X 10(-8) mol/L, respectively. It is produced by Aphanoascus fulvescens. Alternative Names: WF-14865B. Molecular formula: C17H27N5O5. Mole weight: 381.43.
WF-2421
WF-2421 is an aldose reductase inhibitor produced by Humicola grisea. Alternative Names: WF 2421. CAS No. 128429-19-6. Molecular formula: C19H20N2O8. Mole weight: 404.4.
WF-3161
WF-3161 is an antitumor antibiotic produced by a strain of fungus, Petriella guttulata. It inhibited the growth of Trichophyton asteroides. Alternative Names: Antibiotic WF 3161; WF 3161; Antibiotic FR 900261; WF-3161. CAS No. 86402-37-1. Molecular formula: C31H44N4O6. Mole weight: 568.7.
WF-3405
WF-3405 is an antitumor antibiotic isolated from the culture of Amauroascus aureus F-3405. It inhibits various murine tumors including leukemia P388, leukemia L1210 and Lewis lung carcinoma. Alternative Names: Antibiotic WF 3405; WF 3405. CAS No. 108354-43-4. Molecular formula: C9H16O7. Mole weight: 236.22.
WF-3681
WF-3681 is an aldose reductase inhibitor produced by Chaetomella raphigera Swift No. 3681. Alternative Names: WF 3681. CAS No. 105364-56-5. Molecular formula: C13H12O5. Mole weight: 248.23.
WF-5239
WF-5239 is produced by a fungal strain identified as Aspergillus fumigatus Fresenius. It acts as a potent platelet aggregation inhibitor. Alternative Names: WF 5239. CAS No. 91224-36-1. Molecular formula: C9H9NO2. Mole weight: 163.17.
Wilfordine
Wilfordine is an insecticidally active alkaloid found in the Tripterygium wilfordii Hook. f. Grades: >98%. CAS No. 37239-51-3. Molecular formula: C43H49NO19. Mole weight: 883.853.
Wilforlide A
Wilforlide A is extracted from the herb of Tripterygium wilfordii Hook.f. It has obvious anti-inflammatory effect at high-dose. Uses: Wilforlide a has obvious anti-inflammatory effect at high-dose, but has no significant immune suppressive activity. Alternative Names: Regelide; Abruslactone A; (3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one; Wilforlide; Olean-12-en-29-oic acid, 3,22-dihydroxy-, γ-lactone, (3β,20α,22α)-; 3-epiabruslactone A. Grades: ≥98%. CAS No. 84104-71-2. Molecular formula: C30H46O3. Mole weight: 454.68.
Wilfornine A
Wilfornine A is a natural compound of the sesquiterpenoid class found in the roots of Tripterygium wilfordii Hook. f. Grades: >98%. CAS No. 345954-00-9. Molecular formula: C45H51NO20. Mole weight: 925.89.
WIN 64745
WIN 64745 is a nonpeptide antagonist of Neurokinin, which is isolated from Aspergillus sp. SC391. Alternative Names: WIN-64745. Molecular formula: C37H38N6O4. Mole weight: 630.7.