BOC Sciences 11 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
WIN 64821 WIN 64821 is a nonpeptide antagonist of Neurokinin, which is isolated from Aspergillus sp. SC391. Alternative Names: WIN-64821. CAS No. 150881-27-9. Molecular formula: C40H36N6O4. Mole weight: 664.7. BOC Sciences 11
WIN 66306 WIN 66306 is a nonpeptide antagonist of Neurokinin, which is isolated from Aspergillus sp. SC230. Alternative Names: WIN-66306. Molecular formula: C41H52N8O9. Mole weight: 800.9. BOC Sciences 11
WIN 68577 WIN 68577 is a nonpeptide antagonist of Neurokinin, which is isolated from Aspergillus sp. SC230. Alternative Names: WIN 68577; Cyclo(glycyl-L-tryptophyl-L-prolylglycyl-L-valylglycyl-beta-hydroxy-L-tyrosyl). CAS No. 151928-33-5. Molecular formula: C36H44N8O9. Mole weight: 732.8. BOC Sciences 11
Wortmannin It is an antibiotic produced by the strain of Pen. wortmanni 989. It has strong antifungal effect. It is a specific covalent inhibitor of phosphoinositide 3-kinases (PI3Ks) and Polo-Like kinase 1 (PLK1). It is a commonly used cell biology reagent that has been used previously in research to inhibit DNA repair, receptor-mediated endocytosis and cell proliferation. Uses: Immunosuppressive agents. Alternative Names: Antibiotic SL-2052; (1alpha,11alpha)-11-(Acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan-3,7,17-trione; (1S,6bR,9aS,11R,11bR)-1-(Methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate. Grades: 95%. CAS No. 19545-26-7. Molecular formula: C23H24O8. Mole weight: 428.43. BOC Sciences 11
Wrightiin Wrightiin is a new chlorinated depside from Erioderma wrightii Tuck (Ascolichenes). CAS No. 107783-44-8. Molecular formula: C18H17ClO7. Mole weight: 380.78. BOC Sciences 11
WS009 A WS009 A is an endothelin receptor antagonists isolated from Streptomyces sp. no. 89009. II. The IC50 is 5.8 X 10(-6) mol/L. Alternative Names: WS-009A. Molecular formula: C24H25NO10S. Mole weight: 519.52. BOC Sciences 11
WS009 B WS009 B is an endothelin receptor antagonists isolated from Streptomyces sp. no. 89009. II. The IC50 is 6.7 X 10(-7) mol/L. Alternative Names: WS-009B. Molecular formula: C24H25NO11S. Mole weight: 535.52. BOC Sciences 11
WS1279 WS1279 is a lipopeptide isolated from the fermentation broth of Streptomyces willmorei No. 1279. It stimulated the proliferation of mouse bone marrow cells in vitro and accelerated the recovery of granulocyte counts in bone marrow from leukopenia induced by mitomycin C (MMC) in mice. Alternative Names: WS 1279; WS-1279; S-(2,3-bis(palmitoyloxy)propyl)-N-palmitoyl-L-cysteinyl-L-asparaginyl-L-serylglycylglycyl-L-serine. CAS No. 129712-27-2. Molecular formula: C68H125N7O15S. Mole weight: 1312.8. BOC Sciences 11
WS 1358A1 WS 1358A1 is a dehydropeptide (DHP) inhibitor produced by Streptomyces parvulus. Alternative Names: WS-1358A1. Molecular formula: C7H9NO7Na2. Mole weight: 265.13. BOC Sciences 11
WS 1358B1 WS 1358B1 is a dehydropeptide (DHP) inhibitor produced by Streptomyces parvulus. Alternative Names: WS-1358B1. CAS No. 117703-85-2. Molecular formula: C6H7NO7Na2. Mole weight: 251.1. BOC Sciences 11
WS-5995 A WS-5995 A is an anticoccidial antibiotic produced by Streptomyces auranticolor. Alternative Names: Antibiotic WS5995A. Molecular formula: C19H12O6. Mole weight: 336.3. BOC Sciences 11
WS-5995 B WS-5995 B is an antibiotic produced by Streptomyces auranticolor. It exhibits weak ctivity against Proteus and trichomonas vaginalis. Alternative Names: Antibiotic WS5995B. Molecular formula: C19H14O6. Mole weight: 338.3. BOC Sciences 11
WS-5995 C WS-5995 C is an anticoccidial antibiotic produced by Streptomyces auranticolor. Alternative Names: Antibiotic WS5995C. Molecular formula: C19H14O7. Mole weight: 354.3. BOC Sciences 11
WS-7338 A WS-7338 A is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C30H42N6O7. Mole weight: 598.7. BOC Sciences 11
WS-7338 B WS-7338 B is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. It showed good activity in an endothelin receptor binding assay with an IC50 of 2.7 x 10(-7) M. Molecular formula: C31H44N6O7. Mole weight: 612.72. BOC Sciences 11
WS-7338 C WS-7338 C is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C31H44N6O7. Mole weight: 612.72. BOC Sciences 11
WS-7338 D WS-7338 D is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C29H40N6O7. Mole weight: 584.7. BOC Sciences 11
WS-7528 WS-7528 is produced by Streptomyces sp. No. 7528. It inhibited estrogen binding to its receptor protein in rat uterine cytosol. Alternative Names: WS 7528; WS7528; BE-14348B. CAS No. 132147-69-4. Molecular formula: C16H14O5. Mole weight: 286.28. BOC Sciences 11
WS75624 A WS75624 A is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 75624. It also showed other metalloprotease (collagenase and neutral endopeptidase) inhibitory activity with IC50 value of 1 mM/ml. Alternative Names: WS-75624 A; WS 75624 A; WS-75624A. Molecular formula: C18H24N2O5S. Mole weight: 380.5. BOC Sciences 11
WS75624 B WS75624 B is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 75624. It also showed other metalloprotease (collagenase and neutral endopeptidase) inhibitory activity with IC50 value of 1 mM/ml. Alternative Names: WS-75624 B; WS 75624 B; WS-75624B. Molecular formula: C18H24N2O5S. Mole weight: 380.5. BOC Sciences 11
WS79089 A WS79089 A is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 79089. Alternative Names: WS-79089 A; WS 79089 A; WS-79089A. CAS No. 157110-23-1. Molecular formula: C27H20O9. Mole weight: 488.4. BOC Sciences 11
WS79089 B WS79089 B is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 79089. The activity of B is more potent than that of A and C. Alternative Names: WS-79089 B; WS 79089 B; WS-79089B. CAS No. 157110-24-2. Molecular formula: C27H22O10. Mole weight: 506.5. BOC Sciences 11
WS79089 C WS79089 C is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 79089. Alternative Names: WS-79089 C; WS 79089 C; WS-79089C. CAS No. 157110-25-3. Molecular formula: C29H22O10. Mole weight: 530.5. BOC Sciences 11
WS9326A WS9326A is a tachykinin antagonist from Streptomyces violaceusniger No. 9326. Alternative Names: WS-9326A. Molecular formula: C54H68N8O13. Mole weight: 1037.2. BOC Sciences 11
WS-9659 B WS-9659 B is a testosterone 5 alpha-reductase inhibitor isolated from Streptomyces sp. No. 9659. It exhibits weak activity against gram-positive bacteria. Alternative Names: WS-9659B; WS 9659 B. CAS No. 123313-61-1. Molecular formula: C22H23ClN2O. Mole weight: 366.9. BOC Sciences 11
WS-9761 A WS-9761 A is a non-steroidal androgen-receptor antagonist produced by Streptomyces sp. No. 9761. Alternative Names: WS-9761A; WS 9761A; WS9761A. CAS No. 154163-89-0. Molecular formula: C17H16O4. Mole weight: 284.31. BOC Sciences 11
WS-9761 B WS-9761 B is a non-steroidal androgen-receptor antagonist produced by Streptomyces sp. No. 9761. Alternative Names: WS-9761B; WS 9761B; WS9761B. CAS No. 154163-90-3. Molecular formula: C17H16O5. Mole weight: 300.3. BOC Sciences 11
X-14667 A X-14667 A is a monovalent polyether antibiotic of the spiroketal type isolated from fermented cultures of Streptomyces cinnamonensis subsp. Urethanofaciens. It shows activity against gram-positive bacteria. Alternative Names: X 14667 A; X-14667A; X14667 A. Molecular formula: C44H69NO12. Mole weight: 804.02. BOC Sciences 11
X-14667 B X-14667 B is a monovalent polyether antibiotic of the spiroketal type isolated from fermented cultures of Streptomyces cinnamonensis subsp. Urethanofaciens. It shows activity against gram-positive bacteria. Alternative Names: X 14667 B; X-14667B; X14667 B. Molecular formula: C45H70NO12Na. Mole weight: 840.02. BOC Sciences 11
X-14766 A X-14766 A is a monovalent polyether antibiotic of the spiroketal type isolated from fermented cultures of Streptomyces malachitofuscus subsp. downeyi. It shows activity against gram-positive bacteria. Alternative Names: X 14766 A; X-14766A; X14766 A. Molecular formula: C44H63ClO14. Mole weight: 851.41. BOC Sciences 11
X-14847 X-14847 is an aminoglycoside antibiotic isolated from Micromonospora echinospora. It shows weak activity against gram-positive bacteria. Alternative Names: X 14847; 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside; 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol. CAS No. 75802-23-2. Molecular formula: C12H23NO10. Mole weight: 341.31. BOC Sciences 11
X-14868B X-14868B is a polyether antibiotic produced by Nocardia sp. X-14868. It exhibits activity against gram-negative bacteria and coccidium. Alternative Names: X 14868 B; X-14868 B; X14868 B. CAS No. 79296-11-0. Molecular formula: C48H82O17. Mole weight: 931.2. BOC Sciences 11
X-14868C X-14868C is a polyether antibiotic produced by Nocardia sp. X-14868. It exhibits activity against gram-negative bacteria. Alternative Names: X 14868 C; X-14868 C; X14868 C. Molecular formula: C46H78O17. Mole weight: 903.1. BOC Sciences 11
X-14868D X-14868D is a polyether antibiotic produced by Nocardia sp. X-14868. It exhibits activity against gram-negative bacteria. Alternative Names: X 14868 D; X-14868 D; X14868 D. CAS No. 79331-54-7. Molecular formula: C47H80O17. Mole weight: 917.1. BOC Sciences 11
X-14873A X-14873A is a polyether antibiotic produced by the fermentation of Streptomyces sp. X-14873. It is mainly active against Gram-positive bacteria. Alternative Names: X 14873 A; X-14873 A; X14873 A; (5R)-4-Demethyl-4-ethyl-5-hydroxylysocellin. CAS No. 88263-37-0. Molecular formula: C35H62O11. Mole weight: 658.86. BOC Sciences 11
X-14873G X-14873G is a polyether antibiotic produced by the fermentation of Streptomyces sp. X-14873. It is mainly active against Gram-positive bacteria. Alternative Names: X 14873 G; X-14873 G; X14873 G. CAS No. 88263-35-8. Molecular formula: C34H60O8. Mole weight: 596.8. BOC Sciences 11
X-14873H X-14873H is a polyether antibiotic produced by the fermentation of Streptomyces sp. X-14873. It is mainly active against Gram-positive bacteria. Alternative Names: X 14873 H; X-14873 H; X14873 H. CAS No. 88263-36-9. Molecular formula: C34H62O9. Mole weight: 614.8. BOC Sciences 11
X-14885A X-14885A is a divalent cation ionophore produced by a Streptomyces culture isolated from soil sample collected in Wyoming. It is active against gram-positive bacteria and Treponema. Alternative Names: X 14885 A; X-14885 A; X14885 A. CAS No. 83917-57-1. Molecular formula: C27H32N2O7. Mole weight: 496.6. BOC Sciences 11
X-14885B X-14885B is a macrolide antibiotic produced by Streptomyces sp. It shows antifungal activity. Alternative Names: X 14885 B; X-14885 B; X14885 B. Molecular formula: C43H69NO12. Mole weight: 792. BOC Sciences 11
X-206 X-206 is an ionophore antibiotic produced by Streptomyces sp. X 206. It acts as a potent and selective inhibitor of SARS-CoV-2. Alternative Names: Antibiotic X-206. CAS No. 36505-48-3. Molecular formula: C47H82O14. Mole weight: 871.1. BOC Sciences 11
Xanthocidin It is a cyclopentane antibiotic produced by the strain of Str. xanthocidicus. It has weak effect against gram-negative bacteria. Alternative Names: Cyclopentanecarboxylic acid, 2,3-dihydroxy-2-isopropyl-3-methyl-5-methylene-4-oxo-, (+)-; (+)-Xanthocidin; Cyclopentanecarboxylic acid, 2,3-dihydroxy-3-methyl-5-methylene-2-(1-methylethyl)-4-oxo-. CAS No. 28413-93-6. Molecular formula: C11H16O5. Mole weight: 228.24. BOC Sciences 11
Xanthoepocin It is produced by the strain of Penicillum simplicissimum IFO5762. It has anti-gram-positive bacteria activity, it can inhibit Bacillus subtilis and methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.78-1.56 μg/mL. It also has anti-yeast-like fungal activity, and it can inhibit Saccharomyces cerevisiae, Candida albicans and Cryptococcus neoformans with MIC of 3.13-25 μg/mL. It also has weak cytotoxicity to U937 cells with IC50 of 35 μg/mL. Alternative Names: 2,2',3,3'-Tetrahydroxy-9a,9a'-dimethoxy-6,6'-dimethyl-2H,2'H,4H,4'H-1a,1a'-bi[1]benzoxireno[3,4-g]isochromene-4,4',9,9'(9aH,9a'H)-tetrone; [1a,1'a(4H,4'H)-Bi-2H-oxireno[6,7]naphtho[2,3-c]pyran]-4,4',9,9'(9aH,9a'H)-tetrone, 2,2',3,3'-tetrahydroxy-9a,9'a-dimethoxy-6,6'-dimethyl-. Molecular formula: C30H22O14. Mole weight: 606.49. BOC Sciences 11
Xanthothricin It is a nitrogenous heterocyclic antibiotic produced by the strain of Str. sp. and Pseudomonas cocovenenans. It has anti-bacterial and mycobacterium effects. Alternative Names: Toxoflavin; Toxoflavine; Pyrimido(5,4-e)-1,2,4-triazine-5,7-(1H,6H)-dione, 1,6-dimethyl-; 1-methylreumycin; Fervenuline; GNF-PF-67. Grades: >98% by HPLC. CAS No. 84-82-2. Molecular formula: C7H7N5O2. Mole weight: 193.16. BOC Sciences 11
Xenorhabdin I Xenorhabdin is a dithiopyrrolidone antibiotic isolated from Xenorhabdus bovienii. It has antimicrobial and insecticidal activity. CAS No. 92680-94-9. Molecular formula: C11H14N2O2S2. Mole weight: 270.37. BOC Sciences 11
Xenovulene A It is produced by the strain of Acremonium strcturn. It has the effect of inhibiting the binding of Flunitrazepam to γ-aminobutyric acid-benzodiazapine with IC50 of 40 nmol/L. Alternative Names: (2aR,5aR,11E,14aS,14bS,14cS)-4-Hydroxy-5a,9,9,12-tetramethyl-2a,5a,6,9,10,13,14,14a,14b,14c-decahydro-1,5-dioxacyclopenta[cd]cycloundeca[f]inden-3(2H)-one. Molecular formula: C22H30O4. Mole weight: 358.47. BOC Sciences 11
XK-101-2 XK-101-2 is a nucleoside antibiotic isolated from Micromonospora chalcea subsp. It exhibits activity against Mycobacterium phlei and gram-positive bacteria. Molecular formula: C11H13N3O5. Mole weight: 267.24. BOC Sciences 11
XK-90 XK-90 is produced by Streptomyces sp. It is active against Gram-positive and Gram-negative bacteria. Alternative Names: Antibiotic XK 90; 5-(2-Acetylhydrazino)salicylaldehyde. CAS No. 61172-42-7. Molecular formula: C9H10N2O3. Mole weight: 194.19. BOC Sciences 11
XMD16-5 XMD16-5is a novel non-receptor tyrosine kinase TNK2 inhibitor (IC50 = 16 nM and 77 nM for D163E and R806Q mutant TNK2, respectively). Alternative Names: 2-[4-(4-hydroxypiperidin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; XMD-16-5; XMD 16-5; XMD165; XMD-165; XMD 165. CAS No. 1345098-78-3. Molecular formula: C23H24N6O2. Mole weight: 416.48. BOC Sciences 11
XMU-MP-1 XMU-MP-1 is a reversible and selective MST1/2 inhibitor. It suppresses activities of MST1/2 kinase, then activating the downstream effector Yes-associated protein and promoting cell growth. Studies indicated that the pharmacological modulation of MST1/2 kinase activities offered a new way to potentiate tissue repair and regeneration, and XMU-MP-1 is the first lead for the development of targeted regenerative therapeutics. Uses: Targeted regenerative therapeutics. Alternative Names: 4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide; 4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide; Benzenesulfonamide, 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-. Grades: >98%. CAS No. 2061980-01-4. Molecular formula: C17H16N6O3S2. Mole weight: 416.48. BOC Sciences 11
XR651 XR651 is a naphthacene-5,12-dione produced by Amycolatopsis X 16735. Alternative Names: XR-651; XR 651. CAS No. 189697-45-8. Molecular formula: C21H16O5. Mole weight: 348.3. BOC Sciences 11
Y-1005 Y-1005 is a quinone antibiotic isolated from Fusiform yeast stiain BY1. It is effective against gram-positive and -negative bacteria, as well as yeast. Molecular formula: C16H16O6. Mole weight: 304.29. BOC Sciences 11
Yatakemycin It is an antifungal antibiotic produced by the strain of Streptomyces sp. TP-A0356. Its anti-fungal activity against Aspergillus fumigatus, Aspergillus flavus, Aspergillus Niger, Candida albicans and Cryptococcus neoformans is stronger than Amphotericin B and Etraconazole (MIC is 0.0039-0.0156 μg/mL). It also has strong cytotoxicity to P388, HeLa, HEL and other tumor cells (IC50 is 0.01-0.33 μg/mL). Alternative Names: (+)-yatakemycin; Ethanethioic acid, S-(6-(((7bR,8aS)-1,2,4,5,8,8a-hexahydro-2-((6-hydroxy-5-methoxy-1H-indol-2-yl)carbonyl)-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-6-yl)carbonyl)-3,6,7,8-tetrahydro-5-hydroxy-4-methoxybenzo(1,2-b:4,3-b')dipyrrol-2-yl) ester. CAS No. 606136-98-5. Molecular formula: C35H29N5O8S. Mole weight: 679.70. BOC Sciences 11
YF-0200R-A YF-0200R-A is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.5 x 10(-4) M. Alternative Names: YF 0200R-A; YF 0200R A; 8,12-Dihydroxy-2,4-dodecadienoic acid. CAS No. 156368-99-9. Molecular formula: C12H20O4. Mole weight: 228.28. BOC Sciences 11
YF-0200R-B YF-0200R-B is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.2 x 10(-4) M. Alternative Names: YF 0200R-B; YF 0200R B; 8,10,12-trihydroxydodeca-2,4-dienoic acid. CAS No. 156369-00-5. Molecular formula: C12H20O5. Mole weight: 244.28. BOC Sciences 11
YF-044P-D YF-044P-D is a Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. SF-044P. It inhibits Candida albicans aspartyl protease with IC50 of 6.4 X 10(-7) mol/L. Alternative Names: YF 044P-D; YF-044-P-D. CAS No. 158335-52-5. Molecular formula: C43H57N5O9. Mole weight: 787.9. BOC Sciences 11
YKL-05-099 YKL-05-099 has slightly less potent SIK2-inhibitory (IC50 = 40 ± 25 nM) and IL-10-enhancing activities (EC50 = 460 ± 110 nM), but is non-toxic at concentrations ≤ 10 μM and stable in mouse liver microsomes for > 2 hours. Alternative Names: YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. BOC Sciences 11
YKL-06-061 YKL-06-061 is a small molecule serine / threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells. Uses: A potential dermatologic drug. Alternative Names: YKL06-061; YKL 06-061; YKL-06061. CAS No. 2172617-15-9. Molecular formula: C30H37N7O2. Mole weight: 527.67. BOC Sciences 11
YL-704A1 YL-704A1 is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Alternative Names: Yl 704A1; Yl 704 A1. CAS No. 40615-47-2. Molecular formula: C43H71NO15. Mole weight: 842. BOC Sciences 11
YM-170320 YM-170320 is a lipopeptide antibiotic produced by an unidentified fungal strain YL-03706F. It was shown to induce morphological change of colonies in a mutant of Candida tropicalis pK233. It is a novel ergosterol biosynthesis inhibitor. Alternative Names: 5-Amino-4-hydroxy-5-oxo-2-[[3-[[2-[(2,6,10,14-tetramethyl-3-hydroxy-1,7-dioxo-8,10-icosadiene-1-yl)amino]propenoyl]amino]-2-methylpropanoyl]amino]pentanoic acid methyl ester. Molecular formula: C37H62N4O9. Mole weight: 706.91. BOC Sciences 11
YM-181741 YM-181741 is a novel benz[a]anthraquinone antibiotic isolated from the culture broth of actinomycete strain Q57219. It showed selective anti-Helicobacterpylori activity with a MIC value of 0.2 microg/ml. Molecular formula: C19H14O5. Mole weight: 322.3. BOC Sciences 11
YM-202204 YM-202204 is an antifungal antibiotic isolated from the culture broth of marine fungus Phoma sp. Q60596. It exhibited potent antifungal activities against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and also inhibited glycosyl-phosphatidyl-inositol (GPI)-anchoring in yeast cells. Alternative Names: 6'-(2,8-Dihydroxy-1,5,7,9,13,15,17-heptamethyl-nonadeca-3,5,11,13-tetraenyl)-3,4,4'-trihydroxy-6-hydroxymethyl-3,4,5,6-tetrahydro-2H-[2,3']bipyranyl-2'-one. Molecular formula: C37H58O9. Mole weight: 646.8. BOC Sciences 11
YM-24074 YM-24074 is a type I collagenase inhibitor isolated from Streptomyces sp. YL-01869P. Alternative Names: YM 24074. Molecular formula: C21H38N4O5. Mole weight: 426.6. BOC Sciences 11
YM-254890 YM-254890 is a selective Gαq/11 protein inhibitor isolated from Chromobacterium sp. QS3666. YM-254890 (1, 3, and 10 μg/kg) reduces platelet thrombus formation in a cynomolgus monkey model of femoral artery thrombosis. CAS No. 568580-02-9. Molecular formula: C46H69N7O15. Mole weight: 960.1. BOC Sciences 11
YM-266183 YM-266183 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Alternative Names: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41,44-dihydroxy-17'-oxomicrococcin P. Molecular formula: C48H47N13O10S6. Mole weight: 1158.35. BOC Sciences 11
YM-266184 YM-266184 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Alternative Names: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41-hydroxy-44-methoxy-17'-oxomicrococcin P. Molecular formula: C49H49N13O10S6. Mole weight: 1172.37. BOC Sciences 11
YM-30059 YM-30059 is a quinolone antibiotic produced by Arthrobacter sp. YL-02729S. It shows anti-gram-positive bacterial activity and cytotoxicity. It also inhibits li poxygenase. Alternative Names: YM 30059. Molecular formula: C19H25NO2. Mole weight: 299.4. BOC Sciences 11
YM-32890 A YM-32890 A is a macrolide antibiotic isolated from the fermentation broth of cytophaga sp. YL-02905S. It inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast. Alternative Names: YM-32890A; YM-32890-A. Molecular formula: C33H48O6. Mole weight: 540.7. BOC Sciences 11
YM-32890 B YM-32890 B is a macrolide antibiotic isolated from the fermentation broth of cytophaga sp. YL-02905S. Alternative Names: YM-32890B; YM-32890-B. Molecular formula: C33H48O6. Mole weight: 540.7. BOC Sciences 11
YM-47141 YM-47141 is a cyclic-depsipeptide produced by Flexibacter sp. Q17897. It acts as an elastase inhibitor with IC50 of 1.5 X 10(-7) mol/L. Alternative Names: YM 47141; N-(phenylacetyl)-L-phenylalanyl-N-[(3R,6S,9S,14S,17S,18R)-6-(2-amino-2-oxoethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,5,8,11,12,13,16-heptaoxo-1-oxa-4,7,10,15-tetraazacyclooctadecan-17-yl]-L-threoninamide. Molecular formula: C46H62N8O13. Mole weight: 935. BOC Sciences 11
YM-47142 YM-47142 is a cyclic-depsipeptide produced by Flexibacter sp. Q17897. It acts as an elastase inhibitor with IC50 of 3.0 X 10(-7) mol/L. Alternative Names: YM 47142; N-(3-methylbutanoyl)-L-phenylalanyl-N-[(3R,6S,9S,14S,17S,18R)-6-(2-amino-2-oxoethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,5,8,11,12,13,16-heptaoxo-1-oxa-4,7,10,15-tetraazacyclooctadecan-17-yl]-L-threoninamide. Molecular formula: C43H64N8O13. Mole weight: 901. BOC Sciences 11

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