BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Aklavin | It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Alternative Names: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60. |  |
| Akrobomycin | It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Alternative Names: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49. | |
| AK-toxin I | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Alternative Names: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grades: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46. | |
| AK-toxin ll | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Alternative Names: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grades: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| AL-072 | AL072 is an antibiotic against Legionella produced by Strepyomyces sp. AL91. It has strong anti-legionella pneumophila activity. CAS No. 168482-44-8. Molecular formula: C41H76O5. Mole weight: 649.04. | |
| Aladapcin | It is produced by the strain of Nocardia sp. SANK 60484. Alanine in 1-100 ?/kg can enhance the resistance of mice against experimental E. coli infection. Alternative Names: SCHEMBL4061749; DTXSID90921412; N-{2-[(2,6-Diamino-1,7-dihydroxy-7-iminoheptylidene)amino]-1-hydroxypropylidene}alanine. Grades: 95%. CAS No. 114540-27-1. Molecular formula: C13H25N5O5. Mole weight: 331.37. | |
| Alahopcin | It is produced by the strain of Streptamyces albulus subsp. ochra-gerus B-52653. It can resist gram-positive bacteria, negative bacteria and plant pathogenic fungi, and inhibit Collagen-Proline hydroxylase. Alternative Names: (2S)-2-((S)-2-aminopropanamido)-2-(1,5-dihydroxy-2-oxopyrrolidin-3-yl)acetic acid; B-52653. Grades: 95%. CAS No. 82576-50-9. Molecular formula: C9H15N3O6. Mole weight: 261.23. | |
| Alamethicin F50 | It is a neutral linear peptaibol complex with potent antimicrobial activity, containing 20 amino acids with an acetyl and phenylalaninol termini, produced by trichoderma sp. It is an ionopohore, transporting ions through membranes and artificial lipid membrane. It forms voltage-dependent ion channels in lipid bilayer membranes. Alternative Names: Alamethicin F; Alamethicin Rf 50; Atroviridin A; 18-L-Glutamine-alamethicin I; Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-D-Gln-D-Gln-Phe-ol. Grades: >98% by HPLC. CAS No. 56165-93-6. Molecular formula: C92H151N23O24. Mole weight: 1963.32. | |
| Alanylbactobolin | It is produced by the strain of Pseudomonas sp. BMG 13-A7. It has anti-gram-positive bacteria, negative bacteria and tumor activity. Alternative Names: Bactobolin B; L-Alaninamide, L-alanyl-N-(3-(dichloromethyl)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2-benzopyran-4-yl)-, (3S-(3-alpha,4-alpha,4a-beta,5-beta,6-alpha))-; DTXSID80995581; 5-Amino-2-{[3-(dichloromethyl)-1,5,6-trihydroxy-3-methyl-8-oxo-4,4a,5,6,7,8-hexahydro-3H-2-benzopyran-4-yl]amino}-4-oxohexanimidic acid. CAS No. 74141-68-7. Molecular formula: C17H25N3O7Cl2. Mole weight: 454.30. | |
| Alanylclavam | Alanylclavam is a beta-lactam antibiotic produced by Streptomyces clavuligerus NRRL 3585. It is neither a substrate for nor inhibitor of several beta-lactamases, shows antimicrobial activity in defined minimal medium but little or no inhibitory activity in nutrient-rich medium. Alternative Names: Ro-22-5417; 3-(7-Oxo-1-aza-4-oxabicyclo(3.2.0)hept-3-yl)alanine. CAS No. 74758-63-7. Molecular formula: C8H12N2O4. Mole weight: 200.19. | |
| Alazopeptin | It is produced by the strain of Streptomyces griseoplanus. Corneas and Salmonella gallinarum were inhibited, and sarcoma cell 180 was moderately inhibited. Alternative Names: L-Allyl-(6-diazo-5-oxo)-L-norleucyl-(6-diazo-5-oxo)-L-norleucine; Allyl-(6-diazo-5-oxo)-norleucyl-(6-diazo-5-oxo)-norleucine; Allyl-(6-diazo-5-oxo)-L-norleucyl-(6-diazo-5-oxo)-L-norleucine; (Z)-6-[[(Z)-1-carboxy-5-diazonio-4-oxidopent-4-enyl]amino]-1-diazonio-6-oxo-5-(prop-2-enylamino)hex-1-en-2-olate; Ambomycin; Alazopeptin(6CI,7CI,8CI); Norleucine, 6-diazo-5-oxo-N-2-propenylnorleucyl-6-diazo-5-oxo-(9CI). Grades: 99%. CAS No. 1397-84-8. Molecular formula: C15H20N6O5. Mole weight: 364.36. | |
| Albaflavenone | It is produced by the strain of Streptomyces albido flavus. There was resistance to Bacillus thuringiensis with MIC 8-10 ?/mL. Alternative Names: albaflavenone; (+)-epi-isozizaen-5-one; (3S,3aR,6S)-3,7,7,8-tetramethyl-2,3,4,5,6,7-hexahydro-1H-3a,6-methanoazulen-1-one; CHEBI:51460; LMPR0103700006; C17954; Q27122616. Molecular formula: C15H22O. Mole weight: 218.33. | |
| Albocycline | It is produced by the strain of Streptomyces bruneoriseus and Str. roseocinereus. It was mainly resistant to gram-positive bacteria, and the MIC of S. aureus Sitajima strain was 1.56-3.12 ?/mL. The mice were not killed by intraperitoneal injection of 1000 mg/kg. Alternative Names: Albocycline; Ingramycin; CHEMBL4128170; BDBM50274417; MFCD01674465; LS-16246; J-015824; Oxacyclotetradeca-3,6,9-trien-2-one,5-hydroxy-8-methoxy-5,9,13,14-tetramethyl-, (3E,5R,6E,8S,9E,13S,14R)-. Grades: 95%. CAS No. 25129-91-3. Molecular formula: C18H28O4. Mole weight: 308.41. | |
| Albocycline K3 | It is produced by the strain of Streptomyces sp. OH-3984. The concentration of B16 melanoma cells was 15.0 ?/mL, and there was no cytotoxic activity under this concentration. Molecular formula: C17H28O4. Mole weight: 296.40. | |
| Albocycline M-1 | It is produced by the strain of Streptomyces bruneogriseus MCRL 0129. It has very weak anti-gram-negative bacterial activity. Molecular formula: C18H28O5. Mole weight: 324.41. | |
| Albocycline M-2 | It is produced by the strain of Streptomyces bruneogriseus MCRL 0129. It has very weak anti-gram-negative bacterial activity. Molecular formula: C17H28O5. Mole weight: 312.40. | |
| Albofungin | It is produced by the strain of Actinomyces albus var fungatus. It is mainly resistant to gram-positive bacteria and yeast, but not to gram-negative bacteria and filamentous fungi. Alternative Names: 2H-Xantheno(1',2',3':4:5)(1,3)benzodioxino(7,6-g)isoquinoline-5,14(1H,9H)-dione, 13-amino-3,4,8a,13-tetrahydro-4,15,16-trihydroxy-1-methoxy-12-methyl-, (1R-(1-alpha,4-alpha,8a-beta))-; Antibiotic P 42-I; Antibiotic P42-C; (1S,4R,8aR)-13-amino-1,15,16-trihydroxy-4-methoxy-12-methyl-1,2,3,4,8a,13-hexahydro-17H-chromeno[2',3':6,7][1,3]dioxino[4',5',6':4,5]naphtho[2,1-g]isoquinoline-14,17(9H)-dione. Grades: 95%. CAS No. 37895-35-5. Molecular formula: C27H24N2O9. Mole weight: 520.49. | |
| Albonoursin | It is produced by the strain of Streptomyces noursei and Str. albus var fungatus. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria. Alternative Names: Albonoursine; Albonursin; cyclo(DeltaPhe-DeltaLeu); 3-Benzylidene-6-isobutylidene-2,5-dioxopiperazine; cyclo(dehydroleucyl-dehydrophenylalanyl); CHEBI:71609; 2,5-Piperazinedione, 3-(2-methylpropylidene)-6-(phenylmethylene)-, (Z,Z)-. Grades: 99%. CAS No. 1222-90-8. Molecular formula: C15H16N2O2. Mole weight: 256.30. | |
| Alborixin | It is produced by the strain of Streptomyces albus and Str. hygro-scowpicus. It has the function of ion carrier. Alternative Names: Antibiotic S 14750A; 0I21L1W8NY; SCHEMBL2480082; CHEBI:77940; LS-16248; Q27147545; 2H-Pyran-2-acetic acid,6-[(2R,3S)-3-[(2R,5S,6R)-6-[[(2R,3S,5R,6R)-6-[(S)-[(2S,2'R,3'R,5S,5'S)-5'-[(2R,5R,6S)-6-ethyltetrahydro-5-hydroxy-5-methyl-2H-pyran-2-yl]octahydro-2'-hydroxy-2,3',5'-trimethyl[2,2'-bifuran]-5-yl]hydroxymethyl]tetrahydro-6-hydroxy-3,5-dimethyl-2H-pyran-2-yl]methyl]tetrahydro-6-hydroxy-5-methyl-2H-pyran-2-yl]-2-hydroxybutyl]tetrahydro-a,3,5-trimethyl-, (aR,2S,3S,5R,6S)-. Grades: 95%. CAS No. 57760-36-8. Molecular formula: C48H84O14. Mole weight: 885.17. | |
| Albothricin | It is produced by the strain of SIPl-2985. It has anti-gram positive bacteria and negative bacteria activity, but has no effect on enterococcus faecalis and pseudomonas aeruginosa. Alternative Names: [5-(3,6-diaminohexanoylamino)-3-hydroxy-2-(hydroxymethyl)-6-[(5-methyl-4-oxo-3a,6,7,7a-tetrahydro-1H-imidazo[4,5-c]pyridin-2-yl)amino]oxan-4-yl] carbamate; 4H-Imidazo(4,5-c)pyridin-4-one, 2-((4-O-(aminocarbonyl)-2-deoxy-2-((3,6-diamino-1-oxohexyl)amino)-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-5-methyl-, (3aS-(2(R*),3aalpha,7abeta))-. Grades: 95%. CAS No. 103867-06-7. Molecular formula: C20H36N8O7. Mole weight: 500.55. | |
| Albrassitriol | It is a metabolite of Alternaria brassiae. Alternative Names: (1R-(1alpha,4alpha,4aalpha,8abeta))-1,4,4a,5,6,7,8,8a-Octahydro-1-(hydroxymethyl)-2,5,5,8a-tetramethyl-1,4-naphthalenediol; 1,4-Naphthalenediol, 1,4,4a,5,6,7,8,8a-octahydro-1-(hydroxymethyl)-2,5,5,8a-tetramethyl-, (1R-(1alpha,4alpha,4aalpha,8abeta))-. Grades: ≥98%. CAS No. 110557-39-6. Molecular formula: C15H26O3. Mole weight: 254.37. | |
| Alcindoromycin | It is produced by the strain of Actinosporangium sp. C36145. It has anti-gram-positive bacteria and anti-tumor effect. Alternative Names: 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-4-((O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(methylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-6,11-dioxo-2-ethyl-2,5,7,10-tetrahydroxy-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; DTXSID10993434; NSC304415; NSC-304415. Grades: 98%. CAS No. 72586-21-1. Molecular formula: C41H53NO17. Mole weight: 831.85. | |
| Aldecalmycin | It is produced by the strain of Streptomyces sp. MJ147-72F6. Anti-gram-positive bacteria activity, anti-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) activity is the same. MIC: 6.25-25 ?/mL. Alternative Names: 3-[(1R,2S,4aR,6S,8R,8aS)-2-[(E,2S,3R,4S)-4-hydroxy-3,5-dimethyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoct-5-enyl]-1,3,6,8-tetramethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-3-oxopropanal; 1-Naphthalenepropanal, 2-[(2S,3R,4S,5E)-2-(b-D-glucopyranosyloxy)-4-hydroxy-3,5-dimethyl-5-octenyl]-1,2,4a,5,6,7,8,8a-octahydro-1,3,6,8-tetramethyl-b-oxo-, (1R,2S,4aR,6S,8R,8aS)-. Grades: 95%. CAS No. 139953-58-5. Molecular formula: C33H54O9. Mole weight: 594.77. | |
| Aldgamycin F | It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. CAS No. 55141-41-8. Molecular formula: C37H56O16. Mole weight: 756.83. | |
| Aldgamycin G | It is produced by the strain of Streptomyces lavendulae and Str. avidinii. The anti-gram-positive bacteria activity of G was stronger than that of F, and the anti-Staphylococcus aureus activity was similar to that of xiramycin. Alternative Names: 8-Deoxyaldgamycin F; Aldgamycin G; Aldgamycin F, 8-deoxy-; LS-16283; (6Z,14Z)-2-(((5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-9-((6-hydroxy-4,9-dimethyl-2-oxo-1,3,8-trioxaspiro[4.5]decan-7-yl)oxy)-3,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadeca-6,14-diene-5,13-dione; 1,3,8-Trioxaspiro[4.5]decane, aldgamycin F deriv.; 4,17-Dioxabicyclo[14.1.0]heptadecane, aldgamycin F deriv. Grades: 95%. CAS No. 107745-56-2. Molecular formula: C37H56O15. Mole weight: 740.83. | |
| Alectorialin | Alectorialin. Alternative Names: Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, (3,5-dihydroxy-4-methylphenyl)methyl ester; 3-Formyl-2,4-dihydroxy-6-methyl-benzoic acid 3,5-dihydroxy-4-methyl-benzyl ester; 3,5-dihydroxy-4-methylbenzyl 3-formyl-2,4-dihydroxy-6-methylbenzoate. CAS No. 55483-02-8. Molecular formula: C17H16O7. Mole weight: 332.30. | |
| Alectoronic acid | Alectoronic acid. Alternative Names: 2,5,11-trihydroxy-9-(2-oxoheptyl)-2-pentyl-1,2-dihydro-4H,8H-benzo[6,7][1,4]dioxepino[2,3-f]isochromene-4,8-dione; 4H,8H-[2]Benzopyrano[5,6-b][1,4]benzodioxepin-4,8-dione, 1,2-dihydro-2,5,11-trihydroxy-9-(2-oxoheptyl)-2-pentyl-. CAS No. 54226-87-8. Molecular formula: C28H32O9. Mole weight: 512.55. | |
| Aleurodiscal | It is produced by the strain of Aleurodiscus mirabilis. At very low concentrations, Mucor Mie-Hei mycelia were abnormally divergent. Alternative Names: Cyclopenta(4,5)cyclooct(1,2-f)indene-6-carboxaldehyde, 1,2,3,3a,4,6a,7,7a,8,9,10,10a,11,11a-tetradecahydro-10-(1-methylethyl)-3,7a,12-trimethyl-2-(beta-D-xylopyranosyloxy)-, (2S-(2-alpha,3-beta,3a-beta,6a-alpha,7a-alpha,10-beta,10a-beta,11a-beta))-. Grades: 95%. CAS No. 122535-46-0. Molecular formula: C30H46O6. Mole weight: 502.68. | |
| Alisamycin | It is produced by the strain of Streptomyces actuosus (Str. sp. Y-8831582). It has anti-gram-positive bacteria, Candida and other fungi activity, and also has weak inhibition of L1210 leukemia cell activity. Alternative Names: 2,4,6-Heptatrienamide, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-2-yl)-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-; 2,4,6-Heptatrienamide,7-[(1S,2R,6R)-4-[[(2E,4E)-5-cyclohexyl-1-oxo-2,4-pentadienyl]amino]-2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-2-yl]-N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-,(2E,4E,6E)-(9CI); 7-Oxabicyclo[4.1.0]heptane, 2,4,6-heptatrienamidederiv.; (-)-Alisamycin. Grades: 95%. CAS No. 136398-54-4. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| Alizarin 1-methyl ether | Alizarin 1-methyl ether is an anthraquinones isolated from the roots of Morinda officinalis with antiosteoporotic activity. Study shows that 2-Hydroxy-1-methoxyanthraquinone promotes osteoblast proliferation and inhibits osteoclast TRAP activity. Alternative Names: 2-Hydroxy-1-methoxyanthraquinone; 2-Hydroxy-1-methoxy-anthraquinone; 2-hydroxy-1-methoxyanthracene-9,10-dione. Grades: >98%. CAS No. 6170-6-5. Molecular formula: C15H10O4. Mole weight: 254.241. | |
| Alkyl (C12-C14) Dimethyl ethylbenzyl ammoniumchloride | Alkyl (C12-C14) Dimethyl ethylbenzyl ammoniumchloride. Alternative Names: C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride; Quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chloride; AEBDMC. Grades: 78%-82%, mixed solution of ethanol and water. CAS No. 85409-23-0. | |
| Alldimycin A | It is produced by the strain of SE-2385-Al. Alldimycin A inhibited the growth of L1210 cells and the synthesis of DNA and RNA with IC50 of 0.005 ?/mL, 0.92 and 0.47 ?/mL, respectively. Alternative Names: DTXSID40924150; Alldimycin A; Antibiotic ALR 3; 3-Ethyl-3,4,5,7,10-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; 5,12-Naphthacenedione,8-ethyl-7,8,9,10-tetrahydro-1,4,6,7,8-pentahydroxy-10-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,[7R-(7a,8b,10b)]-. Grades: 95%. CAS No. 122397-46-0. Molecular formula: C28H33NO10. Mole weight: 543.56. | |
| Alldimycin B | It is produced by the strain of SE-2385-Al. Alternative Names: 2-ethyl-2,7,10,12-tetrahydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; DTXSID80913801; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,8-tetrahydroxy-7,10-bis((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R-(7alpha,8beta,10beta))-; 5,12-Naphthacenedione,8-ethyl-7,8,9,10-tetrahydro-1,4,6,8-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,[7R-(7a,8b,10b)]-; Alldimycin B; Alpharubicin II. Grades: 95%. CAS No. 97605-82-8. Molecular formula: C36H48N2O12. Mole weight: 700.77. | |
| Alldimycin C | It is produced by the strain of SE-2385-Al. Alternative Names: CTK3I7025; DTXSID50915296; (7R,8R,10S)-7-[(2S,4S,5S,6S)-4-dimethylamino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-ethyl-1,4,6,8,10-pentahydroxy-9,10-dihydro-7H-tetracene-5,12-dione; 2-Ethyl-2,4,7,10,12-pentahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)hexopyranoside; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,4,6,8,10-pentahydroxy-7-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R-(7alpha,8beta,10beta))-. Grades: 95%. CAS No. 94818-02-7. Molecular formula: C28H33NO10. Mole weight: 543.56. | |
| Alliacol A | It is produced by the strain of Marasmium alliaceus. It has weak antibacterial and fungal activity and strong inhibition of DNA synthesis of Ehrlician ascites cancer cells (2-5 ?/mL). The reaction with cysteine to form an admixture greatly reduced the biological activity. Alternative Names: DTXSID80229590; 8H-Oxireno[1,7a]indeno[3a,4-b]furan-6(2H)-one,hexahydro-4a-hydroxy-2,9,9-trimethyl-5-methylene-, (1aR,2R,4aS,7aS,9aR)-; Alliacolide II. Grades: 95%. CAS No. 79232-29-4. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Alliacol B | It is produced by the strain of Marasmium alliaceus. It has weak antibacterial and fungal activity and strong inhibition of DNA synthesis of Ehrlician ascites cancer cells (2-5 ?/mL). The reaction with cysteine to form an admixture greatly reduced the biological activity. Alternative Names: NSC 350186; 8H-Oxireno(1,7a)indeno(3a,4-b)furan-6(2H)-one, 3,4,9,9a-tetrahydro-5-(hydroxymethyl)-2,9,9-trimethyl-, (2R-(1aR*,2alpha,7aS*,9aalpha))-; (1aR,2R,7aS,9aR)-3,4,9,9a-Tetrahydro-5-hydroxymethyl-2,9,9-trimethyl-8H-oxireno[1,7a]indeno[3a,4-b]furan-6(2H)-one; 12-Hydroxydehydroalliacolide. Grades: 98%. CAS No. 79232-33-0. Molecular formula: C15H20O4. Mole weight: 264.32. | |
| Alliacolide | It is produced by the strain of Marasmius alliaceus (Basidiomycetes). It inhibits the activity of Ehrlician ascites cancer cells. Alternative Names: Alliacolide-1; 8H-Oxireno[1,4-b]furan-6(2H)-one, hexahydro-4a-hydroxy-2,5,9,9-tetramethyl-, [2R-(1aR*,2alpha,4abeta,5alpha,7aS*,9aalpha)]-; (1aR,2R,4aS,5S,7aS,9aR)-4a-hydroxy-2,5,9,9-tetramethylhexahydro-8H-oxireno[2',3':1,7a]indeno[3a,4-b]furan-6(2H)-one. CAS No. 66389-08-0. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| Allorhizin | It is the constituent of Psoroma allorhizum. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-6-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,4,9-trimethyl-11-oxo-. CAS No. 84592-16-5. Molecular formula: C18H14Cl2O6. Mole weight: 397.21. | |
| Alnumycin | It is produced by the strain of Streptomyces sp. DSM 11575. The antibacterial spectrum is narrow, and it only has the activity of resistant bacillus subtilis, gambogic micrococcus and other gram-positive bacteria, but has no effect on gram-negative bacteria. It can inhibit the growth of K562 human leukemic cells with IC50 of 0.53 ?/mL. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside | Aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside is a highly esteemed natural compound with anti-inflammatory, antioxidant and anticancer properties. Alternative Names: W-O-b-D-Glucopyranosylaloeemodin; 1,8-dihydroxy-3-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-9,10-dihydroanthracene-9,10-dione. Grades: >98%. CAS No. 50488-89-6. Molecular formula: C21H20O10. Mole weight: 432.38. | |
| Aloin B | Aloin B is an isomer of Aloin, which is a physiologically active anthraquinone present in Aloe vera. Uses: Cathartics. Alternative Names: Isobarbaloin. Grades: ≥98%. CAS No. 28371-16-6. Molecular formula: C21H22O9. Mole weight: 418.39. | |
| α-amino-γ-butyrolactone hydrobromide | α-amino-γ-butyrolactone hydrobromide. CAS No. 6305-38-0. | |
| alpha-Collatolic acid | alpha-Collatolic acid. Alternative Names: Collatolic acid-A''; NSC 646010; 11H-Dibenzo(b,e)(1,4)dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1,6-bis(2-oxoheptyl)-; 3-hydroxy-9-methoxy-6-oxo-1,7-bis(2-oxoheptyl)benzo[b][1,4]benzodioxepine-2-carboxylic acid; α-Collatolic acid. CAS No. 522-52-1. Molecular formula: C29H34O9. Mole weight: 526.57. | |
| α-D-galactopyranosyl 1-phosphate-[1-13C] (dipotassium salt) | α-D-galactopyranosyl 1-phosphate-[1-13C] (dipotassium salt) is the labelled analogue of α-D-galactopyranosyl 1-phosphate (dipotassium salt), which is the phosphate conjugate of α-D-Galactose. α-D-Galactose is a natural aldohexose which is ubiquitous in bacteria, plants, and animals, including human brains. Alternative Names: alpha-D-[1-13C]Gal-1-P (dipotassium salt); α-D-[1-13C]galactopyranosyl 1-phosphate (dipotassium salt); α-D-Galactose-1-13C 1-Phosphate Dipotassium Salt; α-D-Galactopyranose-1-13C 1-(Dihydrogen Phosphate) Dipotassium Salt; α-D-Galactopyranose-1-13C 1-Phosphate Dipotassium Salt; D-Galactose-1-13C 1-Phosphate Dipotassium Salt; α-D-Galactopyranosyl-1-13C Phosphate Dipotassium Salt; α-D-Galactosyl-1-13C Phosphate Dipotassium Salt. Grades: 98%. CAS No. 478518-78-4. Molecular formula: C5[13C]H11K2O9P. Mole weight: 1048.40. | |
| α-Naphthocyclinone | α-Naphthocyclinone. Alternative Names: 6,13-Methanonaphtho[2',3':5,6]cyclohepta[1,2-g]-2-benzopyran-9-butanoic acid, 6-(acetyloxy)-1,3,4,6,8,11,13,14-octahydro-β,7,10,12,15-pentahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-8,11,14-trioxo-, (βR,1S,3R,6S,13R)-; alpha-Naphthocyclinone; (R)-4-((1S,3R,6S,13R)-6-acetoxy-7,8,12,15-tetrahydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-10,11,14-trioxo-1,3,4,6,10,11,13,14-octahydro-6,13-methanonaphtho[2',3':5,6]cyclohepta[1,2-g]isochromen-9-yl)-3-hydroxybutanoic acid; a-Naphthocyclinone. CAS No. 54826-93-6. Molecular formula: C33H30O15. Mole weight: 666.58. | |
| α-Prumycin HCl | α-Prumycin HCl is a carbohydrate antibiotic produced by Str. sp. F-1028. It has anti-fungal activity and weak anti-individual bacterial activity. CAS No. 54612-75-8. Molecular formula: C8H19Cl2N3O4. Mole weight: 292.16. | |
| Alphitonin | Alphitonin is a metabolite related to flavonoids, which is isolated from the heartwood of Australian red ash. Alphitonin has anti-diabetic and anti-oxidant effects. Grades: >95% by HPLC. CAS No. 493-36-7. Molecular formula: C15H12O7. Mole weight: 304.25. | |
| Alphostatin | BMG59-R2 is a peptide antibiotic produced by Bacillus megaterium BNG59-R2. It can inhibit the activity of alkaline phosphatase and also has anti-tumor activity. Alternative Names: L-Glutamic acid, N-(N(sup 2)-(N-(N-L-isoleucyl-L-isoleucyl)-O-phosphono-L-seryl)-L-glutaminyl)-, hydrate; BMG59-R2. Grades: >98%. CAS No. 90119-88-3. Molecular formula: C25H45N6O13P. Mole weight: 668.63. | |
| Altechromone A | Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Alternative Names: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grades: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19. | |
| Alteichin | It is produced by the strain of Alternaria eichorniae. Phytotoxic substances. Alternative Names: alterperylenol; Alteichin; GRK18WHV7F; C10295; (+)-Alterperylenol; AC1L2PAW; Alterperylnol; CHEBI:2614; DTXSID10237401; ZINC4098645; AKOS030213167; (1S,12aR,12bS)-1,4,9,12a-tetrahydroxy-2,12b-dihydro-1H-perylene-3,10-dione; Q27105736; 3,10-Perylenedione,1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1S,12aR,12bS)-; 3,10-Perylenedione, 1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1alpha,12abeta,12balpha)-(+)-. Grades: 95%. CAS No. 88899-62-1. Molecular formula: C20H14O6. Mole weight: 350.32. | |
| Altemicidin | It is produced by the strain of Streptomyces sioyaensis. It has acaricidal and anti-tumor activity. The inhibition IC50 of L1210 and IMC cancer cells was 0.84 and 0.82 ?/mL. Alternative Names: CTK4B4358; DTXSID20925120; 1H-Cyclopenta[c]pyridine-7-carboxylicacid,4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-,(4aR,6S,7R,7aS)-; LS-136376; Q15410226; 6-Hydroxy-7-({[(1-hydroxy-2-sulfamoylethylidene)amino]oxy}carbonyl)-2-methyl-2,4a,5,6,7,7a-hexahydro-1H-cyclopenta[c]pyridine-4-carboximidic acid. Grades: 99%. CAS No. 125399-82-8. Molecular formula: C13H20N4O7S. Mole weight: 376.38. | |
| Alterlactone | Alterlactone is produced from the endolichenic fungus Ulocladium sp. Alterlactone shows strong radical scavenging activity. Alternative Names: 4,9,10-trihydroxy-2-methoxydibenzo[c,e]oxepin-5(7H)-one. Grades: 97.5%. CAS No. 1030376-89-6. Molecular formula: C15H12O6. Mole weight: 288.25. | |
| Alternapyrone | Alternapyrone is a polyketide produced in A. oryzae heterologously expressing the A. solani-derived polyketide synthase gene alt5. CAS No. 676340-02-6. Molecular formula: C28H44O3. Mole weight: 428.65. | |
| Alternaric acid | It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Alternative Names: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grades: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46. | |
| Alternariol 9-methyl ether | Alternariol monomethyl ether is produced from the media of Alternaria alternata strain 261. Alternariol monomethyl ether, an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether possesses cytotoxic and immunosuppressive properties. It has genotoxic properties and can cause oxidative DNA damage. Alternative Names: 2-Biphenylcarboxylic acid, 2',3,4'-trihydroxy-5-methoxy-6'-methyl-, δ-lactone; 6H-Dibenzo[b,d]pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl-; 3,7-Dihydroxy-9-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol 4-O-methyl ether; Alternariol 9-O-methyl ether; Alternariol monomethyl ether; Alternariol-5-O-methyl ether; AME; Djalonensone; NSC 638262. Grades: 98%. CAS No. 23452-05-3. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Althiomycin | It is produced by the strain of Streptomyces althiotious. Anti-Gram-positive bacteria (weak) and E. coli (weak). Alternative Names: Althiomycin; Altiomycin; NSC 102809; 4-Thiazolecarboxamide, N-(1-(4-((2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl)-4,5-dihydro-2-thiazolyl)-2-hydroxyethyl)-2-((hydroxyimino)methyl)-; NSC102809. CAS No. 12656-40-5. Molecular formula: C16H17N5O6S2. Mole weight: 439.47. | |
| Altiloxin A | It is produced by the strain of Phoma asparagi Sacc ALD-8. It is a plant toxin that can inhibit the growth of roots. Alternative Names: (1as,3s,4r,4ar,8ar)-3-hydroxy-3,4a,8,8-tetramethyloctahydro-1ah-naphtho[1,8a-b]oxirene-4-carboxylic acid; (-)-Altiloxin A; CTK5H1580; DTXSID20896902; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS,3R,4R,4aR,8aR)-; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS-(1aalpha,3beta,4alpha,4aalpha,8aS*))-. Grades: 95%. CAS No. 92675-11-1. Molecular formula: C15H24O4. Mole weight: 268.35. | |
| Altiloxin B | It is produced by the strain of Phoma asparagi Sacc ALD-8. Plant toxin. Alternative Names: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid. CAS No. 92675-14-4. Molecular formula: C15H23O4Cl. Mole weight: 302.79. | |
| Altromycin A | It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Alternative Names: methyl 2-(3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)-2-(2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-10-(5-((5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-3-yl)oxy)-4,6-dimethyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl)-2-hydroxyacetate; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-C-methyl-3-(methylamino)-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-(9CI); 4H-Anthra[1,2-b]pyran, D-glycero-D-manno-octonic acid deriv. Grades: 95%. CAS No. 128439-47-4. Molecular formula: C46H57NO18. Mole weight: 911.94. | |
| Altromycin B | It is produced by the strain of Actinomycetes AB 1246E-26. It has anti-Gram-positive bacteria activity, and the MIC for Streptococcus and Staphylococcus is between 0.2-3.12ug/mL. It also has an inhibitory effect on a variety of tumor cells. Alternative Names: GTPL10964; Octonic acid, 3,7-anhydro-8-deoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester; 4H-Anthra[1,2-b]pyran,D-glycero-D-manno-octonic acid deriv.; D-glycero-D-manno-Octonicacid,3,7-anhydro-8-deoxy-2-C-[2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-[2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-a-L-lyxo-hexopyranosyl]-4H-anthra[1,2-b]pyran-5-yl]-5-O-methyl-,methyl ester, (2x)-. Grades: 95%. CAS No. 128461-00-7. Molecular formula: C47H59NO18. Mole weight: 925.96. | |
| Alvespimycin | Alvespimycin (17-DMAG; KOS-1022; NSC 707545) is a potent, water-soluble Hsp90 inhibitor with IC50 of 62 nM. 17-DMAG displays ~2 times potency against human Hsp90 than 17-AAG, with IC50 of 62 nM versus 119 nM. In SKBR3 and SKOV3 cells which overexpress Hsp90 client protein Her2, 17-DMAG causes down-regulation of Her2 with EC50 of 8 nM and 46 nM, respectively, as well as induction of Hsp70 with EC50 of 4 nM and 14 nM, respectively, leading to significant cytotoxicity with GI50 of 29 nM and 32 nM, respectively, consistent with Hsp90 inhibition. In combination with vorinostat, 17-DMAG synergistically induces apoptosis of the cultured MCL cells as well as primary MCL cells, more potently than either agent alone, by markedly attenuating the levels of cyclin D1 and CDK4, as well as of c-Myc, c-RAF and Akt. 17-DMAG treatment at 5 mg/kg or 25 mg/kg three times per week significantly reduces tumor growth of TMK-1 xenografts, by reducing vessel area and numbers of proliferating tumor cells in sections. Consistent the inhibition of FAK signaling in vivo, 17-DMAG treatment at 25 mg/kg three times a week significantly suppresses tumor growth, and metastasis of ME180 and SiHa xenografts in mice. Administration of 17-DMAG at 10 mg/kg for 16 days significantly decreases the white blood cell count and prolongs the survival in a TCL1-SCID transplant mouse model. Uses: Hsp-90 inhibitor; potential anti-cancer drug. Alternative Names: 17-DMAG; KO | |
| AM 4299 A | AM 4299 A is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Alternative Names: Oxiranecarboxylic acid, 3-(((1-(((5-hydroxypentyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-. Grades: >98%. CAS No. 160825-48-9. Molecular formula: C15H26N2O6. Mole weight: 330.38. | |
| AM 4299 B | AM 4299 B is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Alternative Names: N(sup 6)-(N-((3-Carboxyoxiranyl)carbonyl)-L-leucyl)-L-lysine hydrate. Grades: >98%. CAS No. 160825-49-0. Molecular formula: C16H27N3O7. Mole weight: 373.40. | |
| Ambuic acid | Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Alternative Names: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grades: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41. | |
| Amdinocillin pivoxil | Antibiotics, oral. Uses: Anti-bacterial agents. Alternative Names: Pivmecillinam. CAS No. 32886-97-8. Molecular formula: C21H33N3O5S. Mole weight: 439.57. | |
| Amicenomycin A | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. | |
| Amicenomycin B | It is produced by the strain of Streptomyces sp. MJ384-46F6. It has weak anti-gram-positive bacterial activity. Molecular formula: C43H56O16. Mole weight: 828.89. | |
| Amicetin | It is produced by the strain of Streptomuces vinaceusdrappus. It is mainly resistant to gram-positive bacteria and Mycobacterium. The MIC for S.aureus 209P and Mycobacterium tuberculosis H37 Rv were 2.0 and 0.5 μg/mL, respectively, and for Mycoplasma pneumoniae was 12.5 μg/mL. Molecular formula: C29H42N6O9. Mole weight: 618.68. | |
| Amicetin A | It is produced by the strain of Streptomuces vinaceusdrappus. The antibacterial activity is lower than that of Amicetin. Alternative Names: AMICETIN; Amicetin-A; (4S)-N-{(4S)-1-[(2R,5S,6R)-5-{[4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl]oxy}-6-methyloxan-2-yl]-2-oxo-1,2,3,4-tetrahydropyrimidin-4-yl}-4-[(2-methyl-D-seryl)amino]cyclohexa-1,5-diene-1-carboxamide. CAS No. 17650-86-1. Molecular formula: C29H42N6O9. Mole weight: 618.68. | |
| Amicetin B | It is produced by the strain of Streptomuces sp. R-285. The antibacterial activity was lower than that of Amicetin. Alternative Names: Plicacetin; Benzamide, 4-amino-N-(1-(5-((4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)-1,2-dihydro-2-oxo-4-pyrimidinyl)-, (2R-(2-alpha,5-beta,6-alpha))-; DTXSID70962868; 4-amino-N-[1-[5-[5-(dimethylamino)-3,4-dihydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]-2-oxopyrimidin-4-yl]benzamide. CAS No. 43043-15-8. Molecular formula: C25H35N5O7. Mole weight: 517.57. | |
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