BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Amicetin C | It is produced by the strain of Streptomuces vinaceusdrappus. The antibacterial activity was lower than that of Amicetin. CAS No. 102646-94-6. Molecular formula: C56H94N10O19S. Mole weight: 1243.48. |  |
| Amiclenomycin | It is produced by the strain of Streptomyces lavendulae subsp. amiclenomycini. It can inhibit the activity of Mycobacterium, and also has effect on kanamycin resistant Mycobacterium nucleum. Biotin and Desthiobiocin can offset their activities. Alternative Names: Amyclenomycin; 2-Amino-4-(4-amino-2,5-cyclohexadienyl)butyric acid. CAS No. 53696-70-1. Molecular formula: C10H16N2O2. Mole weight: 196.25. | |
| Amicoumacin C | It is produced by the strain of Bacillus pumilus BN-103. It is an antibiotic that resists gram-positive bacteria. Alternative Names: D-ribo-Hexar-6-amic acid, 3-amino-2,3-dideoxy-N-[1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-, γ-lactone, [S-(R*,R*)]-; AI 77Ba; D-ribo-Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo-, γ-lactone. CAS No. 77682-31-6. Molecular formula: C20H26N2O7. Mole weight: 406.43. | |
| Amidepsin E | It is produced by the strain of Humicola sp. FO-5969. It has a weak inhibition of DGAT activity, and the IC50 of DGAT in rat liver microparticles is 124 ?ol/L, respectively. It has no toxicity to Raji cells and no antibacterial activity. Molecular formula: C30H31NO11. Mole weight: 581.57. | |
| Amidepsine B | It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 19.2 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells. CAS No. 169181-29-7. Molecular formula: C28H27NO11. Mole weight: 553.51. | |
| Amidepsine C | It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 51.6 X 10-6mol/L. It also inhibits triacylglycerol formation in intact Raji cells. CAS No. 169181-30-0. Molecular formula: C30H31NO11. Mole weight: 581.57. | |
| Amidepsine D | It is produced by the strain of Humicola sp. FO-2942. It inhibits DGAT activity, and the IC50 of rat liver microsomes DGAT is 17.5 X 10-6 mol/L. It also inhibits triacylglycerol formation in intact Raji cells. Alternative Names: 2,4-di-O-methylgyrophoric acid; 4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-Benzoic Acid 4-Carboxy-3-hydroxy-5-methylphenyl Ester. Grades: ≥95%. CAS No. 79786-34-8. Molecular formula: C26H24O10. Mole weight: 496.46. | |
| Amidinomycin | It is produced by the strain of Streptomyces flavochromogenes. Mainly resistant to gram-positive bacteria (weak). Mice were injected with Amidinomycin 18mg/kg and died within 7 to 10 days. Alternative Names: Myxoviromycin; cis-N-(2-Amidinoethyl)-3-aminocyclopentanecarboxamide; cis-3-Amino-N-(3-amino-3-iminopropyl)cyclopentanecarboxamide. CAS No. 3572-60-9. Molecular formula: C9H18N4O. Mole weight: 198.26. | |
| Amidomycin | It is produced by the strain of Streptomyces sp. PRL-1642. Mainly resistant to yeast and other fungi. Alternative Names: Cyclo((2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl-(2R)-2-hydroxy-3-methylbutanoyl-D-valyl). CAS No. 552-33-0. Molecular formula: C40H68N4O12. Mole weight: 796.98. | |
| Amifostine thiol | Amifostine Thiol is a metabolite of Amifostine. Amifostine thiol activates p53 through a JNK-dependent signaling pathway. Alternative Names: 2-[(3-Aminopropyl)amino]-ethanethiol; N-(2-Mercaptoethyl)-1,3-diaminopropane; NSC 647527; WR 1065. Grades: 95%. CAS No. 31098-42-7. Molecular formula: C5H14N2S. Mole weight: 134.25. | |
| Amikacin | It has a wide antibacterial spectrum and is effective to most kanamycin resistant bacteria. Uses: Anti-bacterial agents. Alternative Names: (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; 1-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A; Amicacin; Amikacillin; Amikacin; Amikozit; Amukin; Antibiotic BB-K 8; Arikace; BAY 41-6551; BAY 416651; BB-K 8; Lukadin; Potentox. Grades: 98%. CAS No. 37517-28-5. Molecular formula: C22H43N5O13. Mole weight: 585.60. | |
| Amines, bis(hydrogenated tallow alkyl), oxidized | UV light stabilizer. Alternative Names: IRGASTAB FS 042; Bis(octadecyl)hydroxylamine; Distearyl hydroxylamine; Bis(hydrogenated tallow alkyl)amines, oxidized. Grades: 65 %. CAS No. 143925-92-2. Molecular formula: C36H75NO. Mole weight: 537.99. | |
| Aminocandin | Aminocandin, a new representative of the echinocandins, has broad-spectrum in vitro activity against Aspergillus and Candida spp. It is used as an anti-infective agent and antifungal drug. It acts by targeting glucans in the fungal cell walls. Alternative Names: IP960; HMR3270; NXL201; L-Proline, 4-[(2-aminoethyl)amino]-N2-[[4'-(octyloxy)[1,1'-biphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-4-(4-hydroxyphenyl)-L-threonyl-L-seryl-3-hydroxy-4-methyl-, (6→15)-lactam, (3S,4S)-; N-[(2R,6S,9S,14aS,15S,16S,20S,23S,25aS)-11-[(2-Aminoethyl)amino]-2,15-dihydroxy-6-[(1R)-1-hydroxyethyl]-23-[(1R)-1-hydroxy-2-(4-hydroxyphenyl)ethyl]-20-(hydroxymethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl]-4'-(octyloxy)-4-biphenylcarboxamide. Grades: 95% by HPLC. CAS No. 227472-48-2. Molecular formula: C56H79N9O14. Mole weight: 1102.28. | |
| Aminochloropentenedioic acid | It is produced by the strain of Streptomyces viridogenes MA5450. It has the activity of resisting gambogic micrococcus. Alternative Names: [R-(Z)]-4-Amino-3-chloro-2-pentenedioic acid; 3-Acpa; 2-Amino-3-chloro-3-pentenedioic; 4-Amino-3-chloro-2-pentenedioic acid; 2-Pentenedioic acid, 4-amino-3-chloro-, (R-(Z))-. CAS No. 90288-29-2. Molecular formula: C5H6ClNO4. Mole weight: 179.56. | |
| Aminoimidazole carboxamide | Aminoimidazole carboxamide is an imidazole derivative and a metabolite of antitumor drugs BIC and DIC. Alternative Names: Aminoimidazole-4-carboxamide, 5-; 5-Aminoimidazole-4-carboxamide. Grades: > 95 % by HPLC. CAS No. 360-97-4. Molecular formula: C4H6N4O. Mole weight: 126.1. | |
| Aminopyrrolnitrin | Aminopyrrolnitrin is a non-steroidal androgen-receptor antagonist produced by Pseudomonas sp. No. 2838. Alternative Names: 3-Chloro-4-(2-amino-3-chlorophenyl)pyrrole; WB2838; WB 2838. Molecular formula: C10H8Cl2N2. Mole weight: 227.09. | |
| Ammajin | Ammajin, a synthetic compound renowned for its formidable antifungal prowess, has been developed to combat fungal infections, including but not limited to, candidiasis and aspergillosis. Its efficacy has been established, thereby, rendering it a potent candidate for therapeutic advancement in the fight against these harrowing ailments. Alternative Names: Ammijin; (-)-Marmesinin; (S)-2-(1-(beta-D-Glucopyranosyloxy)-1-methylethyl)-2,3-dihydro-7H-furo(3,2-g)(1)benzopyran-7-one. Grades: >98%. CAS No. 495-30-7. Molecular formula: C20H24O9. Mole weight: 408.403. | |
| Ammocidin | It is produced by the strain of Saccharothrix sp. AJ 9571. It can reduce the phosphorylation level of mitogen-activated protein kinase (MAPK)S6K. It induces apoptosis in Ras Ba/F3-V12 cells with an IC50 of 66 ng/mL, but not in IL-3 Ba/F3-V12 cells with 100 μg/mL. Alternative Names: Ammocidin A. Molecular formula: C59H96O21. Mole weight: 1141.38. | |
| Amphidinolide F | It is produced by the strain of Amphidinium magniviridis. The IC50 of mouse leukemia L1210 and human epidermal carcinoma KB cells were 1.5 and 3.2 μg/mL, respectively. Alternative Names: 3,26,27-Trioxatricyclo(21.2.1.16,9)heptacos-13-ene-4,18,21-trione,10,11,16-trihydroxy-7,14,15,19-tetramethyl-12-methylene-2-(4-methyl-1,3-pentadienyl). CAS No. 139594-87-9. Molecular formula: C35H52O9. Mole weight: 616.78. | |
| Amphistin | It is produced by the strain of Actinornycete KP-3052. It has weak antibacterial activity. Inhibition of melanoma cell B16 production of melanin without affecting the growth of the cell, IC50 is 55 μmol/L. Alternative Names: amphistin. Molecular formula: C13H21N5O6. Mole weight: 343.33. | |
| Amphomycin | It is produced by the strain of Streptomyces canus. It is primarily resistant to gram-positive bacteria. Alternative Names: Amfomycine; Amfomycinum; Anfomicina; Glumamycin; Amfomycin; A1437E. Grades: >95% by HPLC. CAS No. 1402-82-0. Molecular formula: C58H91N13O20. Mole weight: 1290.41. | |
| Amphotericin A | It is produced by the strain of Streptomyces nodosus. The antifungal spectrum is wide and the activity is strong. Alternative Names: (4E,6E,8E,10E,14E,16E)-3-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid. Grades: ≥ 95%. CAS No. 1405-32-9. Molecular formula: C47H75NO17. Mole weight: 926.09. | |
| Ampicillin Sodium Mixture With Sulbactam Sodium | Ampicillin Sodium Mixture with Sulbactam Sodium is a β-lactamase inhibitor used to enhance the effectiveness of β-lactam antibiotics. Alternative Names: Unacyne; Unacid; Unasyn-S; Yucion-S. CAS No. 117060-71-6. Molecular formula: C25H29N3Na2O9S2. Mole weight: 625.62. | |
| Ampullosporin | Ampullosporin. Molecular formula: C77H127N19O19. Mole weight: 1622.94. | |
| Ampullosporin A | Ampullosporin A is produced by the strain of Sepedonium ampullosporum HKI-0053. Its antibacterial spectrum is narrow. The anti-staphylococcus aureus GS511, Bacillus subtilis, Pseudomonas aeruginosa K599/WT, Escherichia coli SG458, Ocher sporococcus SBUG 549 and Deep red yeast and other bacteria and fungi had only moderate intensity activity, and had no effect on other yeast and candida albicans. It can cause Phoma destructiva to form pigment. Its content is greater than 1mg/kg, which can cause hypothermia and reduce automatic exercise in rats. Alternative Names: N-Acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]-L-glutamamide. CAS No. 197960-94-4. Molecular formula: C77H127N19O19. Mole weight: 1622.94. | |
| Amudol | It is produced by the strain of Penicillum martensii. It has a weak antibacterial activity against S. aureus, E. coli, salmonella, etc. Alternative Names: 2,5-Dihydroxy-4-chlorbenzylalkohol. CAS No. 31302-46-2. Molecular formula: C7H7ClO3. Mole weight: 174.58. | |
| Amycin A | It is produced by the strain of Streptomyces sp. DSM 3816. The activity of Amycin A is weaker than that of Amycin B. CAS No. 116296-63-0. Molecular formula: C62H105N3O21. Mole weight: 1228.50. | |
| Amycin B | It is produced by the strain of Streptomyces sp. DSM 3816. It has the activity of anti-ringworm, microspora, candida, aspergillus and other fungi and gram-positive bacteria such as staphylococcus and streptococcus. Alternative Names: Scopafungin, 23-O-de(carboxyacetyl)-8,47-didemethyl-14,49-dimethyl-. CAS No. 129313-99-1. Molecular formula: C56H101N3O15. Mole weight: 1056.41. | |
| Amylostatin J | It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 79305-08-1. Molecular formula: C25H48NO15. Mole weight: 602.64. | |
| Amylostatin K | It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-64-6. Molecular formula: C25H43NO18. Mole weight: 645.61. | |
| Amylostatin L | It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-66-8. Molecular formula: C31H53NO23. Mole weight: 807.74. | |
| Amylostatin M | It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-67-9. Molecular formula: C31H53NO23. Mole weight: 807.74. | |
| Amylostatin N | It is produced by the strain of Streptomyces diastaticus var. amylostaticus. It can inhibit the activity of Glucoamylase. CAS No. 82642-69-1. Molecular formula: C37H63NO28. Mole weight: 969.88. | |
| Amythiamicin B | It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Alternative Names: L-Prolinamide, N-((2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-(methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-4-thiazolyl)carbonyl)-L-seryl-. CAS No. 156620-48-3. Molecular formula: C50H53N15O9S6. Mole weight: 1200.44. | |
| Amythiamicin C | It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Alternative Names: 4-Thiazolecarboxylic acid,2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-,(octahydro-1,4-dioxopyrrolo(1,2-a)pyrazin-3-yl)methyl ester. CAS No. 156620-47-2. Molecular formula: C50H50N14O9S6. Mole weight: 1183.41. | |
| Amythiamicin D | It is produced by the strain of Amycolatopsis sp. M481-42F4. It has activity against gram-positive bacteria including Multidrug resistant Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus (MR-SA)(MIC 0.1-0.78μg/mL). Not resistant to gram-negative bacteria and fungi. Alternative Names: 4-Thiazolecarboxylic acid,2-(10,11,17,18,23,24,25,26,27,28-decahydro-14-methyl-11-(2-(methylamino)-2-oxoethyl)-18,28-bis(1-methylethyl)-9,16,23,26-tetraoxo-9H,16H-8,5:15,12:22,19:32,29:36,33-pentanitrilo-5H,29H,33H-pyrido(3,2-a1)(1,11,18,25,31,4,7,14,21)pentathiatetraazacyclotetratriacontin-2-yl)-,methyl ester. CAS No. 156620-46-1. Molecular formula: C43H42N12O7S6. Mole weight: 1031.26. | |
| Anantin | It is produced by the strain of Streptomyces coerulescens. It has a competitive binding to the cardiac natriuretic peptide (ANF) receptor. Alternative Names: Anantin (9CI); CYCLO[GLY-PHE-ILE-GLY-TRP-GLY-ASN-BETA-ASP]-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE; GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE; H-GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE-OH; ANANTIN. Grades: 95%. CAS No. 133658-45-4. Molecular formula: C90H111N21O24. Mole weight: 1870.97. | |
| Andrastin A | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 24.9 μmol/L. Alternative Names: NSC 697452; NSC697452; NSC-697452. Grades: ≥95%. CAS No. 174232-42-9. Molecular formula: C28H38O7. Mole weight: 486.60. | |
| Andrastin B | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 47.1 μmol/L. Alternative Names: CHEBI:142862; methyl (3beta,5beta,8alpha,9beta,10alpha,13alpha)-3-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxoandrosta-11,15-diene-14-carboxylate; methyl 3beta-(acetyloxy)-15,19-dihydroxy-4,4,8,12,16-pentamethyl-17-oxo-5beta,8alpha,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate. Molecular formula: C28H40O7. Mole weight: 488.61. | |
| Andrastin C | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 13.3 μmol/L. Molecular formula: C28H40O6. Mole weight: 472.61. | |
| Andrastin D | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 25.7 μmol/L. Alternative Names: CHEBI:142874; methyl (5beta,8alpha,9beta,10alpha,13alpha)-15-hydroxy-4,4,8,12,16-pentamethyl-3,17-dioxoandrosta-11,15-diene-14-carboxylate; methyl 15-hydroxy-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate. CAS No. 184432-08-4. Molecular formula: C26H37O5. Mole weight: 429.57. | |
| Andrimid | It is produced by the strain of Pseudomonas fluorescens. It has anti-gram-positive bacterial activity, has weak effect on gram-negative fine bacteria due to low membrane permeability, and has strong effect on Xanthomonas campestris causing rice crop wilt. CAS No. 108868-95-7. Molecular formula: C27H33N3O5. Mole weight: 479.57. | |
| Androstane-3,17-diol, 5,6-epoxy-, 3,17-diacetate, (3β,5α,6α,17β)- | Androstane-3,17-diol, 5,6-epoxy-, 3,17-diacetate, (3β,5α,6α,17β)-. Alternative Names: 5α-Androstane-3β,17β-diol, 5,6α-epoxy-, diacetate (6CI,7CI,8CI); Androstane-3,17-diol, 5,6-epoxy-, diacetate, (3β,5α,6α,17β)- (9CI); 3β,17β-Diacetoxy-5,6α-epoxy-5α-androstane. CAS No. 2135-24-2. Molecular formula: C23H34O5. Mole weight: 390.51. | |
| Angiolam A | It is produced by the strain of Angiococcus disciformis An d30. Interfered with protein synthesis and had anti-gram-positive bacterial activity. Alternative Names: 1-Oxa-9-azacyclononadec-17-6,8,13,19-tetrone, 15-hydroxy-2-(6-hydroxy-3,7-dimethyl-1,7,9-decatrienyl)-5,10,14,18-pentamethyl-, (2R-(2R*(1E,3S*,6S*,7E),5S*,10R*,14R*,15S*,16S*,17Z))-. CAS No. 99267-41-1. Molecular formula: C34H53NO7. Mole weight: 587.79. | |
| Angiostatin | It is produced by the strain of Dihetrospora catenulata SANK 10481, D. chlamidospora SANK 12181, Verticillum viveostratosum SANK 13358. It has the function of inhibiting Angiotensin converting enzyme. Alternative Names: ANGIO. CAS No. 86090-08-6. Molecular formula: C9H14N2O8. Mole weight: 278.21. | |
| Angolamycin | It is produced by the strain of Streptomyces eurythermus. It has anti-gram-positive bacteria activity and has effect on Mycoplasma pneumoniae Mac. Alternative Names: Sincomycin A; Angolamycin, BRN 6045489; LS-19552; 2-[(14E)-9-[5-(4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-6-methyl-tetrahydropyran-2-yl]oxy-3-ethyl-7-hydroxy-2-[(5-hydroxy-3,4-dimethoxy-6-methyl-tetrahydropyran-2-yl)oxymethyl]-8,12,16-trimethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadec-14-en-10-yl]acetaldehyde. CAS No. 1402-83-1. Molecular formula: C46H77NO17. Mole weight: 916.10. | |
| Anguibactin | It is produced by the strain of Vibrio angullarum. It is an antibiotic that acts as a Siderophore and has a very strong affinity with Fe+3. Alternative Names: (2Z)-N-hydroxy-2-(5-hydroxy-6-oxo-1-cyclohexa-2,4-dienylidene)-N-[2-(3H-imidazol-4-yl)ethyl]thiazolidine-4-carboxamide; ACMC-20m71m; (2Z)-N-hydroxy-2-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-[2-(1H-imidazol-5-yl)ethyl]-1,3-thiazolidine-4-carboxamide. CAS No. 104245-09-2. Molecular formula: C15H16N4O4S. Mole weight: 348.38. | |
| Anguidin | It is produced by the strain of Fusarium anguioides. It showed weak antifungal activity, and 0.03 μg/mL completely inhibited the mitosis of chicken embryo fibroblasts cultured in vitro. The inhibition rate of 0.51mg/kg/d in vivo for 7 consecutive days was 79%, 70% and 50%, respectively, for Walker cancer, sarcoma 37 and sarcoma 180 in rats. Alternative Names: Diacetoxyscirpenol; Anguidine; 4,15-Diacetoxyscirpen-3-ol; CHEBI:4478; 4,15-Di-O-acetylscirpenol; Scirpenetriol 4,15-diacetate; NSC177378; ANG 66; 4,15-Diacetoxyscirp-9-en-3-ol; 4,15-Diacetoxyscirpenol; 12,13-Epoxytrichothec-9-ene-3alpha,4beta,15-triol 4,15-diacetate; 3-alpha-Hydroxy-4-beta,15-diacetoxy-12,13-epoxytrichothec-9-ene. Grades: ≥97%. CAS No. 2270-40-8. Molecular formula: C19H26O7. Mole weight: 366.40. | |
| Anguinomycin A | It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-rat Lewis lung cancer and P388 leukemia activity. It has been reported that it can cause normal cell growth to stop and deformable cell death. Alternative Names: 5-Demethylleptomycin A, KR 2827A. Grades: >95% by HPLC. CAS No. 111278-01-4. Molecular formula: C31H44O6. Mole weight: 512.68. | |
| Anguinomycin B | It is produced by the strain of Streptomyces sp. R2827 and R2827-2. It has anti-mouse Lewis lung cancer and P388 leukemia activity, and in vivo test shows that B has a strong anti-cancer effect on mouse solid cancer. It has been reported that it can stop normal cell growth and cause deformable cell death. Alternative Names: KR-2827A; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-. CAS No. 111278-00-3. Molecular formula: C32H46O6. Mole weight: 526.70. | |
| Angustifolionol | Angustifolionol. Alternative Names: 8-Methyleugenitin; 5-hydroxy-7-methoxy-2,6,8-trimethyl-4H-chromen-4-one; 2,6,8-Trimethyl-5-hydroxy-7-methoxychromone; 4H-1-Benzopyran-4-one, 5-hydroxy-7-methoxy-2,6,8-trimethyl-. CAS No. 478-47-7. Molecular formula: C13H14O4. Mole weight: 234.25. | |
| Angustmycin A | It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity. Alternative Names: Adenosine, 4',5'-didehydro-1'-C-(hydroxymethyl)-; 4',5'-Didehydro-1'-C-(hydroxymethyl)adenosine; 9H-Purin-6-amine, 9-(6-deoxy-β-D-erythro-hex-5-en-2-ulofuranosyl)-; Adenine, 9-(6-deoxy-β-D-erythro-hex-5-enulofuranosyl)-; Angustomycin A; Decoyinin; 5,6-Psicofuranosenyladenine; Antibiotic A 14; Decoyinine; Guvermectin; Wugufengin; Wugufengsu; 9-(6-Deoxy-beta-D-erythro-hex-5-en-2-ulofuranosyl)-9H-purin-6-amine; 9-(6-Deoxy-beta-D-erythro-hex-5-enulofuranosyl)adenine; (2R,3R,4S)-2-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-5-methylenetetrahydrofuran-3,4-diol. Grades: ≥95% by HPLC. CAS No. 2004-4-8. Molecular formula: C11H13N5O4. Mole weight: 279.25. | |
| Angustmycin C | It is produced by the strain of Streptomyces hygroscopicus var. angustmyceticus. It has anti-gram-positive bacteria and mycobacterium activity, and has an inhibitory effect on Walker cancer 256 in rats and adenocarcinoma Ca755 in mice. Alternative Names: Angustmycin C; NSC 53104; Psicofuranosyladenine; 1'-(Hydroxymethyl)adenosine; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-2,5-bis(hydroxymethyl)oxolane-3,4-diol. Grades: ≥98%. CAS No. 1874-54-0. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| Anhydro abiraterone | An impurity of Abiraterone. Abiraterone acetate is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Alternative Names: 3-Androsta-3,5,16-trien-17-yl-pyridine; 3-((8R,9S,10R,13S,14S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine; 17-(3-Pyridyl)androsta-3,5,16-triene. Grades: 95%. CAS No. 154229-20-6. Molecular formula: C24H29N. Mole weight: 331.49. | |
| Anhydrochlortetracycline | Anhydrochlortetracycline is an impurity in the tetracycline antibiotic chlortetracycline, which is formed from tetracycline in an acidic environment. Alternative Names: Anhydroaureomycin. CAS No. 4497-8-9. Molecular formula: C22H21ClN2O7. Mole weight: 460.86. | |
| Anhydrochlortetracycline hydrochloride | Anhydrochlortetracycline is a degradation product of chlorotetracycline formed by acid-catalysed isomerisation of the dimethylamino group at C4. It strongly inhibits the growth of Streptomyces aureofaciem, and shows a rather specific activity against actinomycetes. Alternative Names: (4S,4aS,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride; Anhydroaureomycin Hydrochloride; Anhydro Chlortetracyline Monohydrochloride; [4S-(4α,4aα,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Hydrochloride. Grades: >98% by HPLC. CAS No. 65490-24-6. Molecular formula: C22H22Cl2N2O7. Mole weight: 497.33. | |
| Anhydroepiophiobolin A | Anhydroepiophiobolin A is an ophiobolin with a broad biological profile. It has antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. It is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many bipolaris species. Alternative Names: (6α,18R)-14,18-epoxy-5-oxo-ophiobola-3,7,19-trien-25-al; (2'S,3'S,3aR,5'R,6aR,9aS,10aR)-2,3a,4,4',5',6a,7,9a,10,10a-decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(1H),2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-6-epi-ophiobolin A; [3S-[3α(3'R*,5'S*),3aα,6aα,9aβ,10aβ]]-1,3a,4,4',5',6a,7,9a,10,10a-decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde. Grades: >98% by HPLC. CAS No. 90411-20-4. Molecular formula: C25H34O3. Mole weight: 382.54. | |
| Anhydroexfoliamycin | Anhydroexfoliamycin is a naphthoquinone antibiotic produced by Streptomyces exfoliamycin Tu 1424. Activity against gram-positive bacteria. CAS No. 148084-39-3. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| Anhydrofulvic acid | In acidic condition, Anhydrofulvic acid inhibits mitochondrial respiration of Candida utilis using both succinate and cytochrome C as respiratory substrates, but not using NADH. Anhydrofulvic acid has antifungal activity. Alternative Names: 1H,10H-Pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 7,8-dihydroxy-3-methyl-10-oxo-; 7,8-dihydroxy-3-methyl-10-oxo-1H-pyrano[4,3-b]chromene-9-carboxylic acid. CAS No. 95730-85-1. Molecular formula: C14H10O7. Mole weight: 290.23. | |
| Anhydroophiobolin A | It is the dehydrated analogue of ophiobolin A and a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus bipolaris. It possesses a broad biological profile with antibacterial, antifungal, antitumour, herbicidal and nematocidal activities. Alternative Names: 14,17-Epoxy-5-oxo-3,7,18-ophiobolatrien-21-al; Anhydroophiobolin; (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al; (2'S,3'S,3aR,5'R,6aS,9aS,10aR)-2,3a,4,4',5',6a,7,9a,10,10a-Decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(1H),2'(3'H)-furan]-6-carboxaldehyde; [3S-[3α(3'R*,5'S*),3aα,6aβ,9aβ,10aβ]]-1,3a,4,4',5',6a,7,9a,10,10a-Decahydro-3',9,10a-trimethyl-5'-(2-methyl-1-propenyl)-7-oxo-spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde; 3-Anhydro-cochliobolin; 3-Anhydroophiobolin A. Grades: >95% by HPLC. CAS No. 6026-65-9. Molecular formula: C25H34O3. Mole weight: 382.54. | |
| Anicequol | It is produced by the strain of Penicillum aurantiogriseum Die-rckx TP-F0213. It can inhibit Colon cancer DLD-1 Cells that do not depend on adherent growth with IC50 of 1.2 μg/mL, and cells that depend on adherent growth with IC50 of 40 μg/mL. Alternative Names: NGA0187; (3β,5α,7β,11β,24S)-16-acetoxy-3,7,11-trihydroxyergost-22-en-6-one. CAS No. 440368-05-8. Molecular formula: C30H48O6. Mole weight: 504.70. | |
| Anle138b | Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein. Alternative Names: Anle138b; Anle 138b; Anle-138b; 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b. CAS No. 882697-00-9. Molecular formula: C16H11BrN2O2. Mole weight: 343.17. | |
| Anominine | Anominine is an indole diterpenoid isolated from new Aspergillus species, which has insecticidal activity. Alternative Names: Nominine; (+)-Nominine. Grades: >95% by HPLC. CAS No. 120991-21-1. Molecular formula: C28H39NO. Mole weight: 405.6. | |
| Ansamitocin P 3' | Ansamitocin P 3' is an isomer of Ansamitocin P-3, a potent anti-tumor maytansinoid antibiotic found in Actinosynnema pretiosum, a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. Uses: Adcs cytotoxin. Alternative Names: Ansamitocin P3'; AP-3'; Ansamitocin P-3'; Maytansinol butyrate, Maytansinoid AP-3'. Antibiotic C 15003P3'; iso-Ansamitocin P-3. Grades: >98%. CAS No. 66547-09-9. Molecular formula: C32H43ClN2O9. Mole weight: 635.14. | |
| Ansamitocin PDM-3 | Ansamitocin PDM-3 is an ansamycin antibiotic isolated from Actinosynnema pretiosum, and exhibits antitumor activity. Alternative Names: Ansamitocin P-3; N-Demethylansamitocin P 3; N-Demethylansamitocin P-3. CAS No. 77353-69-6. Molecular formula: C31H41ClN2O9. Mole weight: 621.1. | |
| Ansamitocin PHO-0 | It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Alternative Names: Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-, (15R)-; (15R)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxymaytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO0. CAS No. 79082-29-4. Molecular formula: C28H37N2O9Cl. Mole weight: 581.05. | |
| Ansamitocin PHO-1 | It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Alternative Names: Maytansine, 3-O-acetyl-3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-, (15R)-; (15R)-3-O-Acetyl-3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxymaytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO1. CAS No. 79056-16-9. Molecular formula: C30H39N2O10Cl. Mole weight: 623.10. | |
| Ansamitocin PHO-2 | It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Alternative Names: Maytansine, 2'-de(acetylmethylamino)-15-hydroxy-, (15R)-(9CI); 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO2. CAS No. 79028-00-5. Molecular formula: C31H41N2O10Cl. Mole weight: 637.13. | |
| Ansamitocin PHO-3 | It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Alternative Names: Maytansine, 2'-de(acetylmethylamino)-15-hydroxy-2'-methyl-, (15R)-(9CI); 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO3. CAS No. 79082-28-3. Molecular formula: C32H43N2O10Cl. Mole weight: 651.15. | |
| Ansamitocin PHO-4 | It is produced by the strain of Streptamyces sclerotialus, Str. flavochromogenes, Str. flaviscleroticus, Str. luridus, Chainia nigra, Strertosporangium roseurn, Nocardia sp. N-1231. It has antiprotozoal and antitumor activity. Alternative Names: Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-3-O-(3-methyl-1-oxobutyl)-,(15R)-; (15R)-3-O-De[2-(acetylmethylamino)-1-oxopropyl]-15-hydroxy-3-O-(3-methyl-1-oxobutyl)maytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv.; Antibiotic C 15003PHO4. CAS No. 79056-15-8. Molecular formula: C33H45N2O10Cl. Mole weight: 665.18. | |
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