BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Aspoxicillin | Aspoxicillin is a semi-synthetic penicillin prepared from 6-aminopenicillanic acid (6-APA) or Amoxicillin. It has a broad antibacterial spectrum and has an effect on Pseudomonas aeruginosa. Alternative Names: Aspoxicilina; Aspoxicilline; Aspoxicillinum. Grades: >98%. CAS No. 63358-49-6. Molecular formula: C21H27N5O7S. Mole weight: 493.53. |  |
| Astechrome | Astechrome is an antibiotic produced by Aspergillus terreus (IFO 6123). It has weak antibacterial activity. Molecular formula: (C20H22N3O3)3Fe. Mole weight: 1113.09. | |
| Astepyrone | Astepyrone is an antibiotic produced by Aspergillus terreus (IFO 4100). It has anti-ulcer effect. CAS No. 86925-92-0. Molecular formula: C9H12O5. Mole weight: 200.19. | |
| Asterobactin | Asterobactin is a siderophore antibiotic produced by Nocardia asteroides IFM 0959. It has anti-tumor activity and inhibits HL-60 and HeLa cells at a concentration of 0.2-3.2 μg/mL, and Fe3+ can reduce its activity. Alternative Names: Asterobactin A. CAS No. 482372-30-5. Molecular formula: C34H55N7O13. Mole weight: 769.84. | |
| Asterriquinol D dimethyl ether | Asterriquinol D dimethylether is a fungal metabolite first isolated from Aspergillus terreus as part of the asterriquinone complex. It is cytotoxic to NS-1 mouse myeloma cells with IC50 of 28 μg/ml. It has weak activity against tumor cells and the parasitic protozoan, Tritrichomonas foetus. Alternative Names: 3,3'-(2,3,5,6-tetramethoxy-1,4-phenylene)bis-1H-indole. Grades: ≥95%. CAS No. 287117-66-2. Molecular formula: C26H24N2O4. Mole weight: 428.48. | |
| Asterriquinone CT1 | Asterriquinone CT1 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H26N2O4. Mole weight: 502.56. | |
| Asterriquinone CT2 | Asterriquinone CT2 is an asinquinone antibiotic produced by fungi. It has the effect of inhibiting serine protease in the blood mimicking pathway. Molecular formula: C32H28N2O4. Mole weight: 504.57. | |
| Asterriquinone SU5228 | Asterriquinone SU5228 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Molecular formula: C27H22N2O4. Mole weight: 438.47. | |
| Asterriquinone SU5500 | Asterriquinone SU5500 is a quinone compounds containing indole produced by Aspergillus candidus. It has the effect of inhibiting the binding of Grb-2 adaptor (Adapter) to phosphorylated epidermal growth factor (EGF) receptor tyrosine kinase. Alternative Names: 2,5-Bis[2-(3-methyl-2-butenyl)-1H-indole-3-yl]-3-acetoxy-6-hydroxy-1,4-benzoquinone. Molecular formula: C34H32N2O5. Mole weight: 548.64. | |
| Asticolorin A | Asticolorin A is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-70-6. Molecular formula: C33H30O7. Mole weight: 538.59. | |
| Asticolorin B | Asticolorin B is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93376-71-7. Molecular formula: C33H28O7. Mole weight: 536.57. | |
| Asticolorin C | Asticolorin C is a mycotoxin produced by Aspergillus multicolor MRC 638. CAS No. 93395-44-9. Molecular formula: C33H28O9. Mole weight: 568.57. | |
| Astragaloside A | Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. Alternative Names: Cyclosiversioside F; (3b,6a,16b,24R)-20,24-Epoxy-16,26-dihydroxy-3-(b-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl b-D-glucopyranoside. Grades: >98%. CAS No. 83207-58-3. Molecular formula: C41H68O14. Mole weight: 784.97. | |
| Astragaloside I | Astragaloside I is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside I has cardioprotective effects as well as causing improvement in cognitive function. It has anti-gastric effect. It has been shown to increase gastric pH without changing gastric volume or acid output. Uses: Astragaloside i has cardioprotective effects as well as causing improvement in cognitive function. it has anti-gastric effect and could increase gastric ph without changing gastric volume or acid output. Alternative Names: (3β,6α,16β,20R,24S)-3-[(2,3-Di-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside; Astrasieversianin IV; Cyclosieversioside B; (2S,3R,4S,5R)-5-Hydroxy-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-hydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-9-yl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate. Grades: >98%. CAS No. 84680-75-1. Molecular formula: C45H72O16. Mole weight: 869.04. | |
| Astragaloside II | Astragaloside II is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. It is used in the prevention of cardio-cerebral vascular diseases. It stimulates osteoblast differentiation resulting in bone formation. It exhibits a significant induction of proliferation, differentiation and mineralization in primary osteoblasts. It is a potent MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Uses: Astragaloside ii has cardioprotective effects as well as causing improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it may be used as a potential adjunctive agent for hepatic cancer chemotherapy. Alternative Names: (3b,6a,16b, 20R,24S)-3-[(2-O-Acetyl-b-D-xylopyranosyl)oxy]-20,24-Epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl b-D-glucopyranoside; Astrasieversianin VIII. Grades: >98%. CAS No. 84676-89-1. Molecular formula: C43H70O15. Mole weight: 827.01. | |
| Astragaloside III | Astragaloside III is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Uses: Astragaloside iii has cardioprotective effects as well as causes improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it is an antioxidant. Alternative Names: (3b,6a,16b,20R,24S)-20,24-Epoxy-6,16,25-trihydroxy-9,19-cyclolanostan-3-yl12-O-b-D-glucopyranosyl-b-D-xylopyranoside. Grades: >98%. CAS No. 84687-42-3. Molecular formula: C41H68O14. Mole weight: 784.97. | |
| Asukamycin | Asukamycin, a manumycin-type metabolite, is isolated from Streptomyces nodosus subsp. asukaensis. It exhibits antibiotic properties and inhibits the growth of various tumor cell lines. Alternative Names: asukamycin A1; Manumycin F; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-, (2E,4E,6E)-. Grades: >98%. CAS No. 61116-33-4. Molecular formula: C31H34N2O7. Mole weight: 546.61. | |
| Aszonalenin | Aszonalenin is a nitrogen-containing heterocyclic antibiotic produced by Aspergillus zonatus. It can cause abnormal second division of sea urchin embryo. CAS No. 81797-27-5. Molecular formula: C23H23N3O2. Mole weight: 373.45. | |
| Aszonapyrone A | Aszonapyrone A is a lactone antibiotic produced by Aspergillus zonatus, which has anti-Staphylococcus aureus activity. CAS No. 83103-08-6. Molecular formula: C28H40O5. Mole weight: 456.61. | |
| AT 2433 A1 | AT 2433 A1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Alternative Names: AT2433-A1; 6-Methyl-11-chloro-12-[6-O-[4-(methylamino)-2,4-dideoxy-alpha-L-threo-pentopyranosyl]-4-O-methyl-beta-D-glucopyranosyl]-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione. Grades: >98%. CAS No. 102644-20-2. Molecular formula: C34H35ClN4O9. Mole weight: 679.11. | |
| AT 2433 A2 | AT 2433 A2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Alternative Names: AT 2433-A2; AT2433-A2. Grades: >98%. CAS No. 102644-19-9. Molecular formula: C33H33ClN4O9. Mole weight: 665.09. | |
| AT 2433 B1 | AT 2433 B1 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. It can prolong the survival period of transplanted leukemia P388 mice. Alternative Names: AT2433-B1. Grades: >98%. CAS No. 102622-96-8. Molecular formula: C34H36N4O9. Mole weight: 644.67. | |
| AT 2433 B2 | AT 2433 B2 is an anti-tumor antibiotic produced by Actinomadura melliaura. It has activity against gram-positive bacteria. Alternative Names: AT2433-B2; 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 12-(6-O-(4-amino-2,4-dideoxypentopyranosyl)-4-O-methylhexopyranosyl)-12,13-dihydor-6-methyl-. Grades: >98%. CAS No. 102622-95-7. Molecular formula: C33H34N4O9. Mole weight: 630.64. | |
| Atractyloside potassium salt | Atractyloside potassium salt is the potassium salt of atractyloside, which inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. Uses: Inhibitor of the adenine nucleotide translocator (ant). Alternative Names: (2b,4a,15a)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt; Atractylic acid dipotassium salt; Atractylin (C30 glucoside). Grades: >98%. CAS No. 102130-43-8. Molecular formula: C30H44K2O16S2. Mole weight: 802.99. | |
| Atramycin A | Atramycin A is an isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 4.5 μg/mL. CAS No. 137109-48-9. Molecular formula: C25H24O9. Mole weight: 468.45. | |
| Atramycin B | Atramycin B is an Isotetracenone antitumor antibiotic produced by Streptomyces atratus BY90. It has the activity of inhibiting murine leukemia P388 cells with an ICso of 9.8 μg/mL. CAS No. 137109-49-0. Molecular formula: C25H24O8. Mole weight: 452.45. | |
| Atrovenetin | Atrovenetin is an antibiotic produced by Penicillum herquei PRL 1838 and Pen. atrovenetum SM 683. Molecular formula: C19H18O6. Mole weight: 342.34. | |
| Auramycin A | It is produced by the strain of Streptomyces galilaeus. Auramycin has the ability of anti gram-positive bacteria and tumor, with the LD50 100mg/kg (Mouse, abdominal cavity). Alternative Names: methyl (1R,2R,4S)-4-[(2S,4S,5S,6S)-4-dimethylamino-5-[(2S,4S,5R,6S)-4- hydroxy-6-methyl-5-[(2S,6S)-6-methyl-5-oxo-oxan-2-yl]oxy-oxan-2-yl]oxy -6-methyl-oxan-2-yl]oxy-2,5,7-trihydroxy-2-methyl-6,11-dioxo-3,4-dihyd ro-1H-tetracene-1-carboxylate; auramycin A. Grades: 95%. CAS No. 78173-92-9. Molecular formula: C41H51NO15. Mole weight: 797.84. | |
| Auramycin B | It is produced by the strain of Streptomyces galilaeus. Auramycin has the ability of anti gram-positive bacteria and tumor, with the LD50 100mg/kg (Mouse, abdominal cavity). Alternative Names: auramycin B. CAS No. 78173-91-8. Molecular formula: C41H49NO15. Mole weight: 795.83. | |
| Aurantimycin A | Aurantimycin A is an antibiotic isolated from Streptomyces aurantiacus IMET 43917. Aurantimycin A has activity against Gram-positive bacteria and inhibits cell adhesion. Alternative Names: Aurantimycin; NSC-777195; D-Alanine, (3S)-3-hydroxy-N-[(2R)-2-hydroxy-1-oxo-2-[(2S,5S,6S)-tetrahydro-2-hydroxy-6-methyl-5-(2-methylpropyl)-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-O-methyl-L-serylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-, (6→13)-lactone. Grades: ≥95%. CAS No. 162478-50-4. Molecular formula: C38H64N8O14. Mole weight: 856.96. | |
| Aurantimycinn A | Aurantimycinn A is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn A has strong anti-gram positive bacterial activity, with MIC 0.007-0.08μg/mL, which can be tolerated by mice 1mg/kg (intravenous), 250mg/kg (oral). Molecular formula: C38H64N8O14. Mole weight: 856.96. | |
| Aurantimycinn B | Aurantimycinn B is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn B has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H62N8O14. Mole weight: 854.94. | |
| Aurantimycinn C | Aurantimycinn C is produced by the strain of Streptomyces aurantiacus IMET 43917. Aurantimycinn C has the activity of anti-gram positive bacterial, twice to four times lower than Aurantimycinn A. Molecular formula: C38H60N8O14. Mole weight: 852.93. | |
| Aurantiogliocladin | It is produced by the strain of Gliocladium roseum. Aurantiogliocladin has weak activity of anti-gram positive bacteria, negative bacteria and fungal. Alternative Names: 2,3-DIMETHOXY-5,6-DIMETHYL-2,5-CYCLOHEXADIENE-1,4-DIONE; 2,3-DIMETHOXY-5,6-DIMETHYL-P-BENZOQUINONE; AURANTIOGLIOCLADIN; 2,3-Dimethoxy-5,6-dimethyl-1,4-benzoquinone. Grades: 95%. CAS No. 483-54-5. Molecular formula: C10H12O4. Mole weight: 196.20. | |
| Aureobasidine A | Aureobasidine A is produced by the strain of Aureobasidium pullulans R106. A has strong activity against candida albicans, Cryptococcus neoformans, budding yeast, histocapsular clinophyte and other pathogenic fungi, and its activity exceeds that of amphotericin B in most cases. The effect on candidiasis is bactericidal, and the therapeutic effect on systemic candidiasis in mice is superior to fluconum and amphotericin B. Molecular formula: C60H92N8O11. Mole weight: 1101.42. | |
| Aureoquinone | Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Alternative Names: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20. | |
| Aureothricin | Aureothricin is produced by the strain of Streptomyces celluloflavus. It was active against gram-positive bacteria, negative bacteria and Mycobacterium, and intraperitoneal injection could inhibit the increase of ascites in transplanted mice with Aldrin ascites carcinoma. Alternative Names: Propionylpyrrothione; Farcinin. Grades: >98% by HPLC. CAS No. 574-95-8. Molecular formula: C9H10N2O2S2. Mole weight: 242.32. | |
| Aureusimine B | It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Alternative Names: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grades: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29. | |
| Auroglaucin | It is produced by the strain of Aspergillus spp. Alternative Names: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38. | |
| Australifungin | Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53. | |
| Avenaciolide | It is produced by the strain of Aspergillus avenaceus. A bicyclic bis-butyrolactone; isolated from aspergillus avenaceu; an antifungal agent; inhibits glutamate transport; an atypical ionophore. Alternative Names: Avenaciolid; Furo(3,4-b)furan-2,6(3H,4H)-dione, dihydro-3-methylene-4-octyl- (VAN) (8CI). Grades: >95% by HPLC. CAS No. 20223-76-1. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| Averantin | Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Alternative Names: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grades: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37. | |
| Avermectin A2a | Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Alternative Names: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12. | |
| Avermectin B1a aglycone | It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Alternative Names: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grades: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74. | |
| Avermectin B1a monosaccharide | It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Alternative Names: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grades: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91. | |
| Avidinorubicin | Avidinorubicin is produced by the strain of Streptomyces avidinii. It has anti-gram positive and negative bacterial activity, and has cytotoxicity to tumor cells. Molecular formula: C60H86N4O22. Mole weight: 1215.34. | |
| Avilamycin A | Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Alternative Names: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23. | |
| Avilamycin B | Avilamycin B is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Grades: 95%. CAS No. 73240-30-9. Molecular formula: C59H84Cl2O32. Mole weight: 1376.19. | |
| Avilamycin C | Avilamycin C is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Alternative Names: SCHEMBL6753731. Grades: 95%. CAS No. 69787-80-0. Molecular formula: C61H90Cl2O32. Mole weight: 1406.25. | |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Alternative Names: AVN-492; AVN 492; AVN492. 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine. CAS No. 1220646-23-0. Molecular formula: C17H21N5O2S. Mole weight: 359.45. | |
| Avrainvillamide | Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Alternative Names: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grades: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52. | |
| Awamycin | Awamycin is produced by the strain of Streptomyces sp. No. 80-217. It has anti-gram-positive bacteria and antitumor activity. Alternative Names: Antibiotic Tan 528A; Protostreptovaricin I, 10,25-didemethyl-21-hydroxy-10-(methoxycarbonyl)-19-O-methyl-25-(methylthio)-; Protostreptovaricin-31-oic acid, 25-demethyl-21-hydroxy-19-O-methyl-2S-(methylthio)-, methyl ester. Molecular formula: C38H49NO12S. Mole weight: 743.86. | |
| Axenomycin B | Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities. Molecular formula: C29H38O10. Mole weight: 546.60. | |
| Axinysone B | Axinysone B is a metabolite of the mushroom Anthracophyllum sp. BCC18695. Alternative Names: (-)-Axinysone B; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-4-hydroxy-1,1,7,7a-tetramethyl-, (1aS,4R,7S,7aS,7bR)-. Grades: 98.0%. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Azamulin | Azamulin is an azole derivative of pleuromutilin. Azamulin is a highly selective inhibitor of cytochrome P450 3A4 (CYP3A4). Alternative Names: Azamulinum. Grades: >99% by HPLC. CAS No. 76530-44-4. Molecular formula: C24H36N4O4S. Mole weight: 476.63. | |
| Azaserine | It is produced by the strain of Streptomyces fragilis 04926. Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. Uses: Antibiotics, antifungal; antibiotics, antineoplastic; antimetabolites; antimetabolites, antineoplastic; carcinogens; immunosuppressive agents. Alternative Names: diazoacetate (ester) L-Serine; diazoacetylserine; serine diazoacetate. Grades: 98%. CAS No. 115-02-6. Molecular formula: C5H7N3O4. Mole weight: 173.13. | |
| Azepinomycin | Azepinomycin is produced by the strain of Streptomyces toyokaensis MF71803. It can inhibit Guanase and tumor cell. Alternative Names: 4,5,6,7-Tetrahydro-6-hydroxy-3H-imidazo-(4,5e)(1,4)diazepin-8-one; 3,4,5,6-Tetrahydroimidazo[4,5-e][1,4]diazepine-6,8-diol. CAS No. 89354-15-4. Molecular formula: C6H8N4O2. Mole weight: 168.15. | |
| Azetomycin I | Azetomycin I is produced by the strain of Streptomyces antibioticus 3820. It has the effect of anti-gram positive bacteria, the activity of I and II against Bacillus subtilis was equal to 80% and 70% of that of actinomycin ?. Alternative Names: Azetomicin I; Actinomycin D, 3(sup A)(or 3-(sup B))-(2-azetidinecarboxylic acid)-. CAS No. 59519-94-7. Molecular formula: C61H84N12O16. Mole weight: 1241.39. | |
| Azetomycin II | Azetomycin II is produced by the strain of Streptomyces antibioticus 3820. It has the effect of anti-gram positive bacteria, the activity of I and II against Bacillus subtilis was equal to 80% and 70% of that of actinomycin ?. Alternative Names: Azetomicin II; 3A-(2-Azetidinecarboxylic acid)-3B-(2-azetidinecarboxylic acid)actonomycin D; 3'-Azetidine-3'-azetidine-actinomycin. CAS No. 59481-55-9. Molecular formula: C60H82N12O16. Mole weight: 1227.36. | |
| Azicemicin A | Azicemicin A is produced by the strain of Amycolatopsis sulphurea (MJ126-NF4). The antibacterial activity of A was weak, and the mice were given 150mg/kg intraperitoneally without any acute toxicity. Alternative Names: Benz(a)anthracene-1,6(2H,5H)-dione, 3,4,4a,12b-tetrahydro-9,12-dimethoxy-3-(1-methyl-2-aziridinyl)-3,7,8,10,12b-pentahydroxy-. CAS No. 154163-93-6. Molecular formula: C23H25NO9. Mole weight: 459.44. | |
| Azicemicin B | Azicemicin B is produced by the strain of Amycolatopsis sulphurea (MJ126-NF4). B showed a weak gram-positive bacterial activity and had some effect on Mycobacterium (MIC 6.25-25μg/mL). Alternative Names: Benz(a)anthracene-1,6(2H,5H)-dione, 3,4,4a,12b-tetrahydro-3-(2-aziridinyl)-9,12-dimethoxy-3,7,8,10,12b-pentahydroxy-. CAS No. 162857-75-2. Molecular formula: C22H23NO9. Mole weight: 445.42. | |
| Azidamfenicol | Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide. It is a broad spectrum antibiotic with good activity against gram-negative and anaerobic bacteria. Azidamfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Azidamfenicol has received little research attention with only a few literature citations. Alternative Names: Azidoamphenicol; Leukomycin N. Grades: >99% by HPLC. CAS No. 13838-08-9. Molecular formula: C11H13N5O5. Mole weight: 295.25. | |
| Azidocillin | Azidocillin is produced by the strain of 6-APA and Ampicillin. The activity of anti-hemolytic Streptococcus, Streptococcus pneumoniae and enterococcus is slightly better than penicillin, while staphylococcus aureus, which is sensitive to penicillin, is slightly better than penicillin, and is less stable to penicillinase than amamicillin to influenza bacilli. Stable to acid, oral. The preparation is its sodium salt or potassium salt (melting point 194°C decomposition), used as an antibacterial agent and feed additive. Alternative Names: AZIDOCILLIN; GLOBACILLIN; 6α-(2-Azido-2-phenylacetylamino)penicillanic acid; BRL 2534; SPC 297 D. Grades: 95%. CAS No. 17243-38-8. Molecular formula: C16H17N5O4S. Mole weight: 375.41. | |
| Azinomycin A | Azinomycin A is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively. Alternative Names: 1-Naphthalenecarboxylic acid, 3-methoxy-5-methyl-, 2-((1-(3-(acetyloxy)-4-hydroxy-1-azabicyclo(3.1.0)hex-2-ylidene)-2-oxo-2-((2-oxopropyl)amino)ethyl)amino)-1-(2-methyloxiranyl)-2-oxoethyl ester. CAS No. 106486-77-5. Molecular formula: C30H33N3O10. Mole weight: 595.60. | |
| Azinomycin B | Azinomycin B is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively. Alternative Names: CARZINOPHILIN A; Cardinophyllin. Molecular formula: C31H33N3O11. Mole weight: 623.61. | |
| Azinothricin | Azinothricin is produced by the strain of Streþtomyces sp. X-14950. It has strong anti-gram-positive bacteria and anaerobic bacteria activity, and the resistance of gram-negative bacteria and fungi showed weak activity. Alternative Names: 2H-Pyran-2-acetamide, alpha-ethyl-6-(3-ethyl-1,5-dimethyl-4-oxo-1,5-heptadienyl)-N-(1,8,14,15,18,21,27-heptaaza-21-hydroxy-7-(1-hydroxyethyl)-2,6,9,16,19,22-hexaoxo-4-isopropyl-20-(methoxymethyl)-17,18-dimethyl-5-oxatricyclo(21.4.0.0(sup 10,15))heptacosan-3-yl)tetrahydro-alpha-2-dihydroxy-5-methyl-. CAS No. 101342-90-9. Molecular formula: C49H80N8O15. Mole weight: 1021.20. | |
| Azirinomycin | Azirinomycin is produced by the strain of Streptomyces aureus. It has anti-gram positive and negative bacterial activity. Alternative Names: 3-Methyl-2H-azirine-2-carboxylic acid; 2H-AZIRINE-2-CARBOXYLIC ACID, 3-METHYL-. CAS No. 31772-89-1. Molecular formula: C4H5NO2. Mole weight: 99.09. | |
| Azithromycin dihydrate | Azithromycin dihydrate is the dihydrate form of azithromycin, an orally bioavailable azalide derived from erythromycin, and a member of a subclass of macrolide antibiotics, with anti-bacterial activity. Azithromycin is marginally less active than erythromycin in vitro against Gram-positive organisms, although this is of doubtful clinical significance as susceptibility concentration fall within the range of achievable tissue Azithromycin concentrations. Uses: Anti-bacterial agents. Alternative Names: Azitro; CP 62993; CP-62993; CP62993; Goxal; Odaz; Ribotrex; Toraseptol; Ultreon; XZ-450; XZ450; XZ 450; Zenstavion; Zithromax; Zmax; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, dihydrate, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-; Azrolid; Zithrokan; Zithromac; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one dihydrate. Grades: >98%. CAS No. 117772-70-0. Molecular formula: C38H72N2O12.2H2O. Mole weight: 785.02. | |
| Azithromycin EP Impurity D | Azithromycin EP Impurity D is an impurity of azithromycin, a macrolide antibiotic used for bacterial infections. Alternative Names: Azithromycin F; 14-Demethyl-14-(hydroxymethyl)azithromycin. CAS No. 612069-26-8. Molecular formula: C38H72N2O13. Mole weight: 764.98. | |
| Azomycin | It is produced by the strain of Nocardia mesenterica 446-8A. Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica. It has the activity against gram-positive bacteria, negative bacteria, branch bacteria and trichomonas vaginalis, and has a weak inhibitory effect on Ehrlician ascites cancer. Alternative Names: 2-Nitroimidazole. Grades: >98%. CAS No. 527-73-1. Molecular formula: C3H3N3O2. Mole weight: 113.07. | |
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