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Arisugacin B
Arisugacin B is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4259. Alternative Names: (4aR,6aR,12aS,12bS)-4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-4a,6,6a,12,12a,12b-hexahydro-4H,11H-benzo[f]pyrano[4,3-b]chromene-1,11(5H)-dione. Molecular formula: C27H30O7. Mole weight: 466.52.
Arisugacin H
Arisugacin H is an acetylcholinesterase (AChE) inhibitor produced by Penicillum sp. FO-4260. Molecular formula: C29H36O9. Mole weight: 528.59.
Arizonin A1
Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin A1 has anti-Gram-positive bacteria activity. Alternative Names: 2H-Furo(3,2-b)naphtho(2,3-d)pyran-2,6,11-trione, 3,3a,5,11b-tetrahydro-8-hydroxy-7-methoxy-5-methyl-, (3aR-(3aalpha,5alpha,11balpha))-; Arizonin-A1. CAS No. 108890-87-5. Molecular formula: C17H14O7. Mole weight: 330.29.
Arizonin B1
Arizonins are a complex of quinone antibiotics produced by Actinoplanes arizonaensis. Arizonin B1 has anti-Gram-positive bacteria activity. Alternative Names: Arizonin-B1; (3ar,5r,11br)-7-hydroxy-8-methoxy-5-methyl-3,3a,5,11b-tetrahydro-2h-benzo[g]furo[3,2-c]isochromene-2,6,11-trione. CAS No. 108890-89-7. Molecular formula: C17H14O7. Mole weight: 330.29.
Armentomycin
Armentomycin is an antibiotic produced by Streptomyces armentosus var. armentosus. Armentomycin mainly acts against gram-negative bacteria. Subcutaneous administration of 25mg/kg in mice appears toxic. Alternative Names: (S)-2-amino-4,4-dichlorobutanoic acid. Grades: >98%. CAS No. 10139-00-1. Molecular formula: C4H7Cl2NO2. Mole weight: 172.01.
Armillyl orsellinate
Armillyl orsellinate is an antibiotic produced by Armillaria mellea 619, which has activity against gram-positive bacteria. Molecular formula: C23H30O6. Mole weight: 402.48.
Arohynapene A
Arohynapene A is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. Arohynapene A has no antibacterial activity. Alternative Names: 5-(5-Hydroxy-2,6,8-trimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-5-hydroxy-2,6,8-trimethyl-1-naphthalenyl)-. CAS No. 154445-08-6. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene B
Arohynapene B is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. It has no antibacterial activity. Alternative Names: 5-(2-Hydroxymethyl-6,8-dimethyl-5,6,7,8-tetrahydronaphthalene)-2,4-pentadienoic acid; 2,4-Pentadienoic acid, 5-(5,6,7,8-tetrahydro-2-(hydroxymethyl)-6,8-dimethyl-1-naphthalenyl)-. CAS No. 154445-09-7. Molecular formula: C18H22O3. Mole weight: 286.36.
Arohynapene D
Arohynapene D is an anti-coccidial antibiotic produced by Pemcillum sp. FO-2295. The MIC that Arohynapene D shows toxicity to BHK-21 cells is 1.0 X 10-6 mol/L. Molecular formula: C11H14O3. Mole weight: 194.23.
Arphamenine A
Arphamenine A is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Alternative Names: Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, (αR)-; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]benzenepropanoic acid; Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-, [S-(R*,S*)]-; Arphamenin A. Grades: ≥95%. CAS No. 96551-81-4. Molecular formula: C16H24N4O3. Mole weight: 320.39.
Arphamenine B hydrochloride
Arphamenine B is an enzyme inhibitor produced by Chromobacteriuin violaceum HMG361-CF4. It can inhibit the activity of aminopeptidase B, and can inhibit sarcoma 180 and IMC cancer. Alternative Names: Benzenepropanoic acid, α-[3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, monohydrochloride, [S-(R*,S*)]-; Arphamenine B monohydrochloride; Benzenepropanoic acid, α-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-, (αR)-, monohydrochloride; (αR)-α-[(3S)-3-Amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxybenzenepropanoic acid monohydrochloride. Grades: ≥95%. CAS No. 88465-81-0. Molecular formula: C16H24N4O4.HCl. Mole weight: 372.85.
ARQ-087
ARQ-087, also known as Derazantinib, is an oral fibroblast growth factor receptor (FGFR) inhibitor with antitumor property. FGFR plays a role in the regulation of key cellular behaviors including proliferation, cell differentiation and so on. FGFR dysregulation is considered as a driver in multiple cancers. ARQ 087 binds to FGFR and effectively inhibits the activation of FGFR thus can suppress tumorigenesis and tumor growth. Alternative Names: ARQ 087; ARQ087; ARQ-087; Derazantinib; (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine. Grades: ≥98%. CAS No. 1234356-69-4. Molecular formula: C29H29FN4O. Mole weight: 468.576.
Artepillin C
Artepillin C, a bioactive substance present in Brazilian green propolis, exhibits promising anti-inflammatory and antitumor activities. Its therapeutic potential extends to a wide spectrum of ailments, encompassing cancer, bacterial infections, and inflammatory conditions. Alternative Names: ARTEPILLIN C; ArtepillinC,fromPropolis; (E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]propenoic acid; 3,5-Bis(3-methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid; 3,5-Diprenyl-4-hydroxycinnamic acid; 3,5-Diprenyl-4-hydroxy-trans-cinnamic acid; 4-Hydroxy-3,5. Grades: 98%. CAS No. 72944-19-5. Molecular formula: C19H24O3.
Arthoniaic acid
Arthoniaic acid is a carbonyl compound. Alternative Names: 4-Carboxy-3-methoxy-5-(2-oxoheptyl)phenyl 2,4-dihydroxy-6-(2-oxoheptyl)benzoate; Arthonia acid. CAS No. 25556-24-5. Molecular formula: C29H36O9. Mole weight: 528.59.
Arthothelin
Arthothelin is a xanthene compound. Alternative Names: Xanthen-9-one, 2,4,5-trichloro-1,3,6-trihydroxy-8-methyl- (8CI); 2,4,5-Trichloro-1,3,6-trihydroxy-8-methyl-9H-xanthen-9-one. CAS No. 20716-96-5. Molecular formula: C14H7Cl3O5. Mole weight: 361.56.
Arugomycin
Arugomycin is an onion ring antibiotic produced by Streptomyces violochromogenes 1098-AV2. It has anti-Gram-positive bacteria activity, and its anti-Ehrlich ascites cancer activity is similar to that of Acalamycin, but lower than that of Doxorubicin. Alternative Names: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin, arugomycin deriv. CAS No. 88465-80-9. Molecular formula: C80H112N2O37. Mole weight: 1693.73.
Arylomycin A2
Arylomycin A is a lipopeptide compound with double aryl bridge produced by Streptomyces sp. Tu 6076. It has anti-Gram-positive bacteria activity. The most sensitive bacteria is Rhodococcus Ehmpolis. Molecular formula: C42H60N6O11. Mole weight: 824.97.
Arylomycin B1
Arylomycin B is a lipopeptide compound with double aryl bridge produced by Streptomyces sp. Tu 6075. It has anti-Gram-positive bacteria activity. The most sensitive bacteria is Rhodococcus Ehmpolis. The B series compounds are more active than the corresponding A series compounds. Molecular formula: C42H59N7O13. Mole weight: 869.97.
AS-183
AS-183 is an enzyme inhibitor produced by Scedosporium sp. SPC-15549. Alternative Names: 3(2H)-Furanone, 2-hydroxy-2,4-dimethyl-5-(1,3,5,7-tetramethylnonyl)-. Grades: >98%. CAS No. 147317-12-2. Molecular formula: C19H34O3. Mole weight: 310.47.
AS-186c
AS-186c is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 11.5 μmol/L. Alternative Names: 1-(7-{2-[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]-3-hydroxy-5-methylphenyl}-8,12-dihydroxy-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C43H46O12. Mole weight: 754.82.
AS-186d
AS-186d is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Penicillum asperosporum KY1635. The IC50 for inhibiting ACAT was 12.4 μmol/L. Alternative Names: 1-(8,12-dihydroxy-7-{3-hydroxy-2-[6-hydroxy-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoyl]-5-methylphenyl}-4-methoxy-10-methyl-5-oxo-7,8-dihydro-5H-dibenzo[b,h][1,5]dioxonin-3-yl)-3-methylbutyl acetate. Molecular formula: C44H50O13. Mole weight: 786.86.
Asciminib
Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. Uses: Tyrosine kinase inhibitors. Alternative Names: ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide. CAS No. 1492952-76-7. Molecular formula: C20H18ClF2N5O3. Mole weight: 449.843.
Ascochin
Ascochin is a fungal metabolite found in Ascochyta, which has antifungal, antibacterial and phytotoxic activities. Alternative Names: (S)-(+)-Ascochin. Grades: >95% by HPLC. CAS No. 935699-58-4. Molecular formula: C12H10O5. Mole weight: 234.2.
Ascochitine
Ascochitine is an antibiotic produced by Ascochita fabae and Asc. pisi. It is mainly resistant to fungi such as Xanthomonas oryzae and Xanthomonas oryzae, and has a control effect on some diseases of rice and tomato. Molecular formula: C15H16O5. Mole weight: 276.28.
Ascochlorin
Ascochlorin is an antibiotic produced by Ascochyta viciae. It has anti-candida albicans activity. It can inhibit Newcastle disease virus and herpes simplex virus plaque formation in chicken embryo fibroblast culture. Alternative Names: Ilicicolin D. Grades: >98%. CAS No. 26166-39-2. Molecular formula: C23H29ClO4. Mole weight: 404.93.
Ascofuranone
Ascofuranone is an antibiotic produced by Ascochyta viciae. On the agar plate, it can inhibit the plaque formation of some viruses, and is not resistant to bacteria and other microorganisms. Oral administration in rats can reduce blood lipids. Grades: >98%. CAS No. 38462-04-3. Molecular formula: C23H29ClO5. Mole weight: 420.93.
Ascomatic acid
It is a new dibenzofuran and depside from the Lichen Bunodophoron patagonicum. Alternative Names: 2-Dibenzofurancarboxylic acid, 3,7-dimethoxy-1,9-dimethyl-; 3,7-dimethoxy-1,9-dimethyldibenzofuran-2-carboxylic acid. CAS No. 93796-74-8. Molecular formula: C17H16O5. Mole weight: 300.31.
Ascosteroside
Ascosteroside is an antifungal antibiotic produced by Ascotricha amphitricha. It has activity against yeasts (such as Candida albicans, Saccharomyces cerevisiae, etc.) and filamentous fungi, but has no antibacterial effect. Alternative Names: (3S,5R,10S,13R,14S,15R,17R)-3-[(2R,3S,4S,5R,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxy-tetrahydropyran-2-yl]oxy-17-[(1R)-1,5-dimethyl-4-methylene-hexyl]-15-hydroxy-10,13-dimethyl-4-methylene-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-14-carboxylic acid; (3S,5R,10S,13R,14S,15R,17R)-3-[(2R,3S,4S,5R,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-15-hydroxy-10,13-dimethyl-4-methylidene-17-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-14-carboxylic acid. Molecular formula: C37H58O9. Mole weight: 646.85.
Aselacin A
Aselacin A is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor. CAS No. 156223-06-2. Molecular formula: C46H68N8O11. Mole weight: 909.08.
Aselacin B
Aselacin B is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor. CAS No. 156223-07-3. Molecular formula: C46H66N8O12. Mole weight: 923.06.
Aselacin C
Aselacin C is a substance produced by Acremonium sp. AB 2093T-194 and AB 2068-51 that inhibits the binding of endothelin (en-dothelin) to its receptor. It has the effect of inhibiting the binding of endothelin to its receptor. Alternative Names: Glycin, N-(N-(N-(N-(N-(N2-(1,9-dioxo-10,12-octadecadienyl)-D-glutaminyl)-L-threonyl)-beta-alanyl)-D-tryptophyl)-D-seryl)-, omicron-lactone. CAS No. 156223-08-4. Molecular formula: C46H66N8O11. Mole weight: 907.06.
Asenapine maleate
Asenapine Maleate is a 5-HT receptor antagonist used for the treatment of acute schizophrenia and bipolar mania. It is a second-generation (atypical) antipsychotic agent. Alternative Names: (3aR,12bR)-rel-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-Butenedioate; trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole; Org 5222. Grades: >98%. CAS No. 85650-56-2. Molecular formula: C21H20ClNO5. Mole weight: 401.84.
Ashimycin A
Ashimycin A is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Alternative Names: 2,4-Dicarbamimidamido-3,5,6-trihydroxycyclohexyl 2-C-carboxypentofuranosyl-(1->4)-2-deoxy-2-(methylamino)hexopyranosyl-(1->2)-5-deoxy-3-C-formylpentofuranoside. CAS No. 123482-11-1. Molecular formula: C27H47N7O18. Mole weight: 757.70.
Ashimycin B
Ashimycin B is an aminoglycoside antibiotic produced by Streptomyces griseus FT3-4. It has a broad-spectrum antibacterial activity, but is lower than streptomycin. Alternative Names: D-Streptamine, O-2-deoxy-2-((hydroxyacetyl)methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-. CAS No. 123482-12-2. Molecular formula: C23H41N7O14. Mole weight: 639.61.
Asparaginyl-asparagine is a dipeptide composed of two L-asparagine. It is an incomplete breakdown product of protein digestion or protein catabolism. It has a role as a Mycoplasma genitalium metabolite. Alternative Names: L-Asparagine, L-asparaginyl-; H-NN-OH; Asn-Asn; L-Asparaginyl-L-asparagine; Asparagylasparagin; L-Asn-L-Asn; (S)-4-Amino-2-((S)-2,4-diamino-4-oxobutanamido)-4-oxobutanoic acid. Grades: ≥95%. CAS No. 58471-52-6. Molecular formula: C8H14N4O5. Mole weight: 246.22.
Asparaginyl-isoleucine
Asparaginyl-isoleucine is a dipeptide composed of asparagine and isoleucine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Isoleucine, L-asparaginyl-; L-asparaginyl-L-isoleucine; Asn-Ile; NI dipeptide; H-NI-OH; H-L-Asn-L-Ile-OH. Grades: ≥98%. CAS No. 438533-59-6. Molecular formula: C10H19N3O4. Mole weight: 245.28.
Asparaginyl-lysine
Asparaginyl-Lysine is a dipeptide composed of asparagine and lysine. Alternative Names: Asn-Lys; NK dipeptide. CAS No. 22677-58-3. Molecular formula: C10H20N4O4. Mole weight: 260.29.
Asparaginyl-phenylalanine
Asparaginyl-Phenylalanine is a dipeptide composed of asparagine and phenylalanine. Alternative Names: L-Asparaginyl-L-phenylalanine; Asn-Phe. CAS No. 22849-01-0. Molecular formula: C13H17N3O4. Mole weight: 279.29.
Asparaginyl-serine
Asparaginyl-serine is a dipeptide composed of asparagine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Serine, L-asparaginyl-; Asn-Ser; L-Asn-L-Ser; L-Asparaginyl-L-serine; H-NS-OH; Asparaginylserine. Grades: ≥95%. CAS No. 92172-15-1. Molecular formula: C7H13N3O5. Mole weight: 219.20.
Asparaginyl-tryptophan
Asparaginyl-tryptophan is a dipeptide composed of asparagine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Tryptophan, L-asparaginyl-; H-NW-OH; L-asparagyl-L-tryptophan; Asn-Trp; Asparaginyltryptophan; L-Tryptophan, N-L-asparaginyl-. Grades: ≥95%. CAS No. 74105-03-6. Molecular formula: C15H18N4O4. Mole weight: 318.33.
Asparenomycin A
Asparenomycin A is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. Alternative Names: Asparenomycin. CAS No. 76466-24-5. Molecular formula: C14H16N2O6S. Mole weight: 340.35.
Asparenomycin B
Asparenomycin B is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 79366-72-6. Molecular formula: C14H18N2O6S. Mole weight: 342.37.
Asparenomycin C
Asparenomycin C is a carbapenem antibiotic produced by Streptomyces tokunonensis sp. (PA-31088) and Srt.argenteolus (PA-39504). It has anti-gram-positive and negative bacteria activity, can inhibit a variety of β-lactamases, and also has an effect on β-lactamase-producing strains. CAS No. 81018-71-5. Molecular formula: C14H16N2O5S. Mole weight: 324.35.
Aspartocin D
Aspartocin D is a minor analogue of the amphomycin complex, a family of lipopeptide antibiotic produced by Streptomyces canus. Aspartocin D has the activity against Gram-positive bacteria with MIC of 0.125 μg/ml for B. subtilis and is presumed to act by inhibiting bacterial cell wall peptidoglycan synthesis, however its bioprofile and potential utility has not been extensively investigated. The antibacterial activity is calcium-dependent, with MICs ranging from 0.06-4 and 0.25-8 μg/ml for B. subtilis and S. aureus, respectively, in the presence of higher (2.5 mM) to lower (0.125 mM) calcium concentrations. Alternative Names: N-[(3Z)-9-methyl-1-oxo-3-decen-1-yl]-L-alpha-aspartyl-(2S,3R)-2,3-diaminobutanoyl-(2R)-2-piperidinecarbonyl-(3S)-3-methyl-L-alpha-aspartyl-L-alpha-aspartylglycyl-L-alpha-aspartylglycyl-(2R,3R)-2,3-diaminobutanoyl-L-valyl-L-proline(11→2)-lactam. Grades: ≥95% by HPLC. CAS No. 1562369-96-3. Molecular formula: C56H87N13O20. Mole weight: 1262.37.
Aspartyl-asparagine. Alternative Names: L-α-Aspartyl-L-asparagine. CAS No. 13433-11-9. Molecular formula: C8H13N3O6. Mole weight: 247.21.
Aspartyl-histidine
Aspartyl-Histidine is a dipeptide composed of aspartate and histidine. Alternative Names: Asp-His; L-alpha-aspartyl-L-histidine. CAS No. 22677-56-1. Molecular formula: C10H14N4O5. Mole weight: 270.24.
Aspartyl-isoleucine
Aspartyl-isoleucine. Alternative Names: alpha-Asp-Ile; L-Aspartyl-L-Isoleucine; L-alpha-aspartyl-L-isoleucine. CAS No. 13433-07-3. Molecular formula: C10H18N2O5. Mole weight: 246.26.
Aspartyl-serine
Aspartyl-serine is a dipeptide composed of aspartic acid and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Serine, L-a-aspartyl-; Aspartylserine; (S)-3-Amino-N-((S)-1-carboxy-2-hydroxy-ethyl)-succinamic acid; Asp-Ser; α-L-Asparagyl-L-serine; L-Asp-L-Ser; H-DS-OH; L-alpha-aspartyl-L-serine; (S)-3-amino-4-(((S)-1-carboxy-2-hydroxyethyl)amino)-4-oxobutanoic acid. Grades: ≥95%. CAS No. 6403-13-0. Molecular formula: C7H12N2O6. Mole weight: 220.18.
Aspartyl-threonine
Aspartyl-Threonine is a dipeptide composed of aspartate and threonine. Alternative Names: aspartylthreonine; Asp-Thr; DT dipeptide; D-T Dipeptide. CAS No. 13433-17-5. Molecular formula: C8H14N2O6. Mole weight: 234.21.
Asperaldin
Asperaldin is an aldose reductase (ECLLL21) inhibitor produced by Aspergillus niger CFR-1046. Alternative Names: 1,4-Naphthalenedione, 8-(hexyloxy)-2,6-dihydroxy-. CAS No. 561297-46-9. Molecular formula: C16H18O5. Mole weight: 290.31.
Aspercolorin
An atypical cyclic tetrapeptide in which one of the amino acids is a 5-methoxyanthranilic acid. Aspercolorin is a fungal metabolite produced by Aspergillus versicolor. It is used as a secondary metabolite standard in polyphasic taxonomy for the identification of aspergillus versicolor. Alternative Names: 1,2,3,5,6,7,8,9,10,11,12,17,18,18a-Tetradecahydro-10-benzyl-14-methoxypyrrolo[1,2-a][1,4,8,11]benzotetraazacyclotetradecine-5,9,12,18-tetrone; 10-benzyl-14-methoxy-1,2,3,7,8,10,11,18a-octahydrobenzo[e]pyrrolo[1,2-a][1,4,8,11]tetraazacyclotetradecine-5,9,12,18(6H,17H)-tetraone; Cyclo(β-alanylprolyl-2-amino-5-methoxybenzoylphenylalanyl). Grades: >97% by HPLC. CAS No. 29123-52-2. Molecular formula: C25H28N4O5. Mole weight: 464.51.
Asperfuran
Asperfuran is an antifungal antibiotic produced by Asperfuran oryzae. Asperfuran has fungal activity and can inhibit fungal chitin synthase, but the effect can be completely offset by lecithin. It also has inhibitory effect on HeLa S3 cells and L1210 cells. Alternative Names: Asperfuran; 5,7-Benzofurandiol, 2,3-dihydro-2-(1,3-pentadienyl)-, (R-(E,E))-. CAS No. 129277-10-7. Molecular formula: C13H14O3. Mole weight: 218.25.
Aspergillic acid
Aspergillic acid is an antibiotic produced by Aspergillus flavus. Aspergillic acid has anti-gram-positive bacteria, gram-negative bacteria, mycobacteria and Candida albicans activities. Alternative Names: 3-Isobutyl-6-sec-butyl-2-hydroxypyrazine 1-oxide. CAS No. 490-02-8. Molecular formula: C12H20N2O2. Mole weight: 224.30.
Aspergillimide
Aspergillimide is a product produced by Aspergillus sp. IMI 337664 with anthelmintic effect. Alternative Names: Asperparaline A; (1R,3'R,5aR,8aR,9aS)-rel-(-)-tetrahydro-1,1',8,8,11-pentamethyl-spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3'-pyrrolidine]-2',5',10-trione; VM 55598; Antibiotic VM 55598. Grades: >98%. CAS No. 195966-93-9. Molecular formula: C20H29N3O3. Mole weight: 359.46.
Aspergillin PZ
Asperillin PZ is an isoindole fungal metabolite produced by Aspergillus awamoli. 0.089 μmol/L can cause the morphological changes of the conidia of Pear spores. It may possess anti-cancer and anti-tumor properties. Alternative Names: (1R,2S,5R,5aS,5bS,8R,8aS,9R,11aR,13aR)-2,3,4,5,5a,5b,8,8a,9,10,13,13a-Dodecahydro-2-hydroxy-5,7,8-trimethyl-9-(2-methylpropyl)-1,5-epoxy-1H-cyclohepta[3,4]benz[1,2-d]isoindole-11,12-dione; (+)-Aspergillin PZ; Aspergilline PZ. Grades: >98%. CAS No. 483305-08-4. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspergillumarin
Aspergillus A is a dihydroisocoumarin derivative isolated from the culture broth of the marine-derived fungus Aspergillus. CAS No. 1392495-06-5. Molecular formula: C14H16O4. Mole weight: 248.27.
Aspergin
Aspergin is an antibiotic produced by Aspergillus sp., with activity against gram-positive bacteria. CAS No. 40434-07-9. Molecular formula: C19H26O3. Mole weight: 302.41.
Asperlactone
Asperlactone is a biologically active polyketide metabolite produced mainly from Aspergillus westerdijkiae. Asperlactone is a nematicidal, an insecticidal, an antibacterial and an antifungal agent. Alternative Names: 2(5H)-Furanone, 5-((1S)-1-hydroxyethyl)-3-((2S,3S)-3-methyloxiranyl)-, (5R)-; [2S-[2α[S*(R*)],3β]]-5-(1-hydroxyethyl)-3-(3-methyloxiranyl)-2(5H)-furanone. Grades: ≥98%. CAS No. 76375-62-7. Molecular formula: C9H12O4. Mole weight: 184.19.
Asperlicin
Asperlicin is a non-peptide cholecystokinin (Cholecystokinin, CCK) produced by Aspergillus alliaceus. It has the effect of antagonizing CCK. A and its derivatives are promising for the treatment of ulcers and pancreatic tumors. Alternative Names: Asperlicin A. CAS No. 93413-04-8. Molecular formula: C31H29N5O4. Mole weight: 535.59.
Asperlin
Asperlin is an antibiotic produced by Aspergillus nidulans CMI 94163. Asperlin has anti-gram-positive bacteria, negative bacteria, mycobacterial activity, and inhibits KB cells. Alternative Names: Asperlin; U 13933. Grades: >98%. CAS No. 30387-51-0. Molecular formula: C10H12O5. Mole weight: 212.20.
Asperphenamate
Asperphenamate is a fungal secondary metabolite isolated from Aspergillus flavipes. Asperphenamate has been found in a broad range of Pencillium and Aspergillus species and even in plants, as a product of endophytic fungi. Asperphenamate has weak antitumor activity. It inhibits proliferation of T47D and MDA-MB-231 breast and HL-60 leukemia cancer cell lines (IC50s = 92.3, 96.5, and 97.9 μM, respectively) and inhibits yeast α-glucosidase activity (IC50 = 8.3 μM). Asperphenamate is also used to synthesize N-Benzoyl-O-(N'-(1-benzyloxycarbonyl-4-piperidiylcarbonyl)-D-phenylalanyl)-D-phenylalaninol (BBP), an asperphenamate derivative that inhibits human breast carcinoma MCF-7 cell growth. Alternative Names: (S)-N-Benzoyl-L-phenylalanine 2-(Benzoylamino)-3-phenylpropyl Ester; N-Benzoyl-phenylalanine 2-benzoylamino-3-phenylpropyl Ester; N-Benzoyl-L-phenylalaninol N-benzoyl-L-phenylalaninate; Anabellamide; Asjanin; NSC 306231; Auranamide. Grades: ≥95%. CAS No. 63631-36-7. Molecular formula: C32H30N2O4. Mole weight: 506.59.
Aspersitin
Aspersitin is an antibiotic produced by Aspergillus parasiticus. It has anti-gram-positive and negative bacteria activity. CAS No. 86996-89-6. Molecular formula: C14H21NO4. Mole weight: 267.32.
Aspicilin
It is obtained from the lichens Aspicilia calcarea and A. gibbosa. Alternative Names: (-)-Aspicillin; (5R,6S,7R,18S,E)-5,6,7-trihydroxy-18-methyloxacyclooctadec-3-en-2-one; (3E,5R,6S,7R,18S)-5,6,7-Trihydroxy-18-methyloxacyclooctadeca-3-en-2-one; Oxacyclooctadec-3-en-2-one, 5,6,7-trihydroxy-18-methyl-, (3E,5R,6S,7R,18S)-. Grades: 99%. CAS No. 52461-05-9. Molecular formula: C18H32O5. Mole weight: 328.44.
Aspiculamycin
Aspiculamycin is a nucleoside peptide antibiotic produced by Streptomyces toyocaensis var. aspiculamyceticus. It has weak anti-Gram-positive bacteria, negative bacteria, mycobacteria and mycoplasma activity, and has the effect of repelling worms, nematodes and killing worms. Alternative Names: Aspiculamycin; Quingfengmycin; Gougerotin. Molecular formula: C19H30O10N8. Mole weight: 530.49.
Aspochalasin D
Aspochalasin D is a potent inhibitor of mammalian tumor cell lines, first isolated from Aspergillus microcysticus. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D was found that it can strongly induce the formation of actin-containing rodlets in the cytoplasm of treated fibroblasts. Alternative Names: 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-. Grades: ≥95%. CAS No. 71968-02-0. Molecular formula: C24H35NO4. Mole weight: 401.54.
Aspochalasine A
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Aspochalasine A has anti-bacterial and fungal activity. Molecular formula: C24H33NO4. Mole weight: 399.52.
Aspochalasine E
Aspochalasine is an antibiotic produced by Aspergillus microcysticus and an unidentified fungus FA2277. Molecular formula: C24H33NO3. Mole weight: 383.52.
Aspochracin
Aspochracin is a cyclic tripeptide isolated from Aspergillus first. Aspochracin is toxic to caught worms (LD50 = 100 μg/g) and silkworms. Grades: >95% by HPLC. CAS No. 22029-09-0. Molecular formula: C23H36N4O4. Mole weight: 432.56.