BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Alternative Names: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grades: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52.
Idarubicinol-d4
Idarubicinol-d4 is a labelled Idarubicinol. Alternative Names: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grades: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55.
Idasanutlin
Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Alternative Names: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grades: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487.
Idelalisib
Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Alternative Names: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grades: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432.
Ifenprodil Tartrate
Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. Uses: Adrenergic alpha-antagonists. Alternative Names: Ifenprodil (tartrate). Grades: >98%. CAS No. 23210-58-4. Molecular formula: 2(C21H27NO2).C4H6O6. Mole weight: 800.98.
Iguratimod
Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Alternative Names: T 614; T-614; T614; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; Careram; Kolbet; UNII-4IHY34Y2NV. Grades: 0.98. CAS No. 123663-49-0. Molecular formula: C17H14N2O6S. Mole weight: 374.367.
IK-930
IK930, a novel TEAD inhibitor, sensitizes KRAS and EGFR mutant tumors to oncogene targeted therapy. CAS No. 2563892-44-2. Molecular formula: C19H19F3N4O2S. Mole weight: 424.44.
IL-15 Protein, Human
Interleukin-15 (IL-15) is an inflammatory cytokine that stimulates the expression of tumor necrosis factor α (TNF-α), IL-1β, and inflammatory chemokines. IL-15 is secreted primarily by monocytes and macrophages, which are activated by the products of viral or bacterial infections. IL-15 binds and signals through a trimetric receptor consisting of a common gamma chain, IL-2Rβ, and IL-15Rα. Similar to IL-2, IL-15 triggers the proliferation of normal B lymphocytes and the production of immunoglobulins. IL-15 also stimulates the proliferation of NK cells and activated CD4+ and CD8+ T cells, promoting the induction of cytolytic effector cells such as lymphokine-activated killer cells. IL-15 Protein, Human is a pleiotropic cytokine that stimulates the activity of T, B, and NK cells. Alternative Names: rHuIL-15; IL15. Grades: ≥95%. Mole weight: ~12.8 kDa.
IL-22 Protein, Cynomolgus (HEK293, His)
Interleukin-22 (IL-22) is a member of the IL-10 cytokine family and is produced by many immune cells involved in the body's immune microenvironment. IL-22 plays a key role by binding to the IL-22 receptor complex (IL-22R) and subsequently activating the downstream signaling pathway of IL-22R. IL-22 is used in the study of several connective tissue diseases (CTDs), such as systemic lupus erythematosus, rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, and dermatomyositis. Alternative Names: Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18. Grades: ≥95%. Mole weight: 32-42 kDa.
Iloprost
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. Alternative Names: Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid; Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)-; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374. Grades: 98%. CAS No. 78919-13-8. Molecular formula: C22H32O4. Mole weight: 360.49.
Ilunocitinib
Ilunocitinib is a Janus kinase (JAK) inhibitor (veterinary use). Alternative Names: {1-(cyclopropanesulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile; 2-(3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile; 3-Azetidineacetonitrile, 1-(cyclopropylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-. CAS No. 1187594-14-4. Molecular formula: C17H17N7O2S. Mole weight: 383.43.
Imatinib Related Substance B
An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Alternative Names: Imatinib (Piperidine)-N,N-dioxide; 4-[(4-Methyl-1,4-dioxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grades: > 95%. CAS No. 571186-93-1. Molecular formula: C29H31N7O3. Mole weight: 525.62.
Imazethapyr
a herbicide that that is used in biological studies to evaluate the effect on non-target vegetation within agroecosystems. Uses: Herbicides. Alternative Names: (±)-5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)nicotinic Acid; (±)-Imazethapyr; 5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl) Nicotinic Acid; AC 263499; CL 263499; Fabian; Imazethapyr; Pivot; Pursuit; Pursuit 10. Grades: > 95%. CAS No. 81335-77-5. Molecular formula: C15H19N3O3. Mole weight: 289.34.
Imeglimin hydrochloride is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. Alternative Names: EMD 387008 hydrochloride; EMD387008 hydrochloride; EMD-387008 hydrochloride. Grades: >98%. CAS No. 775351-61-6. Molecular formula: C6H14ClN5. Mole weight: 191.7.
Imetelstat
Imetelstat is a telomerase inhibitor, also a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a "telomerase template antagonist"), a mechanism of action which differs from that for the antisense oligonucleotide-mediated inhibition of telomerase activity through telomerase mRNA binding. Inhibition of telomerase activity in tumor cells by imetelstat results in telomere shortening, which leads to cell cycle arrest or apoptosis. Alternative Names: Rytelo; GRN163L. Grades: ≥90%. CAS No. 868169-64-6.
Imidacloprid
Imidacloprid. Uses: A neonicotinoid; the active ingredient in certain neuro-active insecticides. Alternative Names: 1-((6-chloro-3-pyridinyl)methyl)-n-nitro-2-imidazolidinimin; 1-(6-chloro-3-pyridylmethyl)-n-nitroimidazolidin-3-ylideneamine; bay-ntn33893; confidor200sl; confidorsl; merit(insecticide); provado; RELEVO. Grades: 95%. CAS No. 138261-41-3. Molecular formula: C9H10ClN5O2. Mole weight: 255.66.
Imidazolidinyl Urea
Imidazolidinyl urea is used as an antimicrobial preservative and a formaldehyde releaser. Uses: An antimicrobial preservative used in cosmetics. Alternative Names: Imidurea; N,N'-Methylenebis[N'-(3-hydroxymethyl-2,5-dioxo-4-imidazolidinyl)urea]; Abiol; 1,1'-Methylenebis(3-(3-(Hydroxymethyl)-2,5-Dioxoimidazolidin-4-yl)Urea). Grades: ≥98%. CAS No. 39236-46-9. Molecular formula: C11H16N8O8. Mole weight: 388.29.
Imidodisulfurylchloride
Imidodisulfurylchloride. CAS No. 15873-42-4. Molecular formula: Cl2HNO4S2. Mole weight: 214.10.
Imidodisulfurylfluoride
Imidodisulfurylfluoride. Alternative Names: Bis(fluorosulfonyl)amine; bis(fluorosulfonyl)imide. Grades: 98%. CAS No. 14984-73-7. Molecular formula: F2HNO4S2. Mole weight: 181.14.
Imiglucerase
Imiglucerase. Alternative Names: Imiglucerase; Cerezyme; Unii-Q6U6J48bwy. CAS No. 154248-97-2. Molecular formula: C2532H3843N671O711S16.
An agonist of TLR7 with immune response modifying activity, Approved for basal cell carcinoma, In Phase III for VIN and CIN, Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Uses: An immune response modifier. it stimulates the production of interferon-a. Alternative Names: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308; Aldara; TMX-101; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamine; Aldara; Beselna; Keravort; R 837; R837; S 26308; TMX 101; Zartra; Zyclara. Grades: >98%. CAS No. 99011-02-6. Molecular formula: C14H16N4. Mole weight: 240.30.
Imiquimod hydrochloride
Imiquimod hydrochloride is an immune response modifier. It acts as a toll-like receptor 7 agonist. It is commonly used topically to treat warts on the skin of the genital and anal areas. It is also used to treat certain diseases of the skin, including skin cancers, such as basal cell carcinoma, Bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis. It can lead to the activation of Langerhans cells, which subsequently migrate to local lymph nodes to activate the adaptive immune system when applied to skin. Alternative Names: R 837 hydrochloride; R837 hydrochloride; R-837 hydrochloride; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, hydrochloride (1:1); 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, monohydrochloride; Imiquimod monohydrochloride. Grades: ≥95%. CAS No. 99011-78-6. Molecular formula: C14H17ClN4. Mole weight: 276.76.
Imlunestrant
Imlunestrant, an orally active selective estrogen receptor degrader (SERD) with potential antineoplastic activity, can be used in the ER+, HER2-advanced breast cancer research. Alternative Names: LY-3484356; (R)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol; 5H-(1)Benzopyrano(4,3-c)quinolin-2-ol, 5-(4-(2-(3-(fluoromethyl)-1-azetidinyl)ethoxy)phenyl)-8-(trifluoromethyl)-, (5R)-. Grades: 98%. CAS No. 2408840-26-4. Molecular formula: C29H24F4N2O3. Mole weight: 524.51.
Inaxaplin
Inaxaplin is an apolipoprotein L1 (APOL1) function inhibitor. Alternative Names: 1H-Indole-3-propanamide, 5,7-difluoro-2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-. Grades: 98%. CAS No. 2446816-88-0. Molecular formula: C21H18F3N3O3. Mole weight: 417.38.
Inclisiran
Inclisiran is a medication approved for the treatment of people with atherosclerotic cardiovascular disease (ASCVD), ASCVD risk equivalents and heterozygous familial hypercholesterolemia (HeFH). It is a small interfering RNA (siRNA) that binds to PCSK9 messenger RNA, resulting in decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. Alternative Names: ALN-PCSsc; ALN-60212; Leqvio; Inclisiran sodium; ALN-PCS; Leqvio; RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-Am-Gm-sp-Am-sp-Am), complex with RNA (Cm-sp-Um-sp-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Um-dT-Um-Um-Gm-Cm-Um-Um-Um-Um-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1). Grades: 98%. CAS No. 1639324-58-5. Molecular formula: C529H707F12N176O316P43S6. Mole weight: 16339.48.
Indan-2-yl-methylamine hydrochloride
Indan-2-yl-methylamine hydrochloride. Alternative Names: (2,3-Dihydro-1H-inden-2-yl)methanamine hydrochloride; 2,3-dihydro-1H-inden-2-ylmethanamine hydrochloride. Grades: 95%. CAS No. 178955-07-2. Molecular formula: C10H14ClN. Mole weight: 183.68.
Indapamide EP Impurity A
Indapamide EP Impurity A is an impurity of Indapamide, which is a medication commonly used as a diuretic and antihypertensive agent. Indapamide belongs to the class of thiazide-like diuretics and is primarily used to treat high blood pressure (hypertension) and fluid retention (edema). Alternative Names: (2RS)-2-methyl-1-nitroso-2,3-dihydro-1H-indole; (±)-2-methyl-1-nitrosoindoline; rac 1-Nitroso-2-Methylindoline. Molecular formula: C9H10N2O. Mole weight: 162.19.
Indazole-Cl
Indazole-Cl is a selective estrogen receptor modifier (SERM) and ERβ agonist. Alternative Names: 3-Chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol; 2H-Indazol-5-ol, 3-chloro-2-(4-hydroxyphenyl)-; Ind-Cl. Grades: ≥95%. CAS No. 848142-62-1. Molecular formula: C13H9ClN2O2. Mole weight: 260.68.
Indene
Indene is a useful research chemical. Alternative Names: 1H-indene. Grades: ≥ 90%. CAS No. 95-13-6. Molecular formula: C9H8. Mole weight: 116.16.
Indigo Carmine
Indigo carmine is a dye that is used as a tissue stain, pH indicator, and tool for determining hypochlorite in solutions. Alternative Names: C.I. Acid Blue 74; 2-(1,3-Dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic Acid Disodium Salt; 5,5'-Indigodisulfonic Acid Disodium Salt; Acid Blue 74; Acid Blue W; Acid Leather Blue IC; Airedale Blue IN; Amacid Brilliant Blue; Aniline Carmine Powder; Ariavit Indigo Carmine; Atul Indigo Carmine; Basovit Blue 665E; Blue 2; Bucacid Indigotine B; Canacert Indigo Carmine; Carmine Blue; Carmine Indigo; Cilefa Blue R; Disodium 5,5'-indigodisulfonate; Disodium 5,5'-Indigotin Disulfonate; Dolkwal Indigo Carmine; Edicol Supra Blue X; Eurocert Indigo Carmine 311811. Grades: ≥90%. CAS No. 860-22-0. Molecular formula: C16H8N2Na2O8S2. Mole weight: 466.35.
Indirubin-3'-monoxime
Indirubin-3'-monoxime, a chemical derivative of indirubin, is an inhibitor of GSK-3β with dual affinity for CDK1/5 receptor. It significantly inhibited the proliferation and induced apoptosis in all of the RCC cell lines. Alternative Names: indirubin-3'-oxime; 3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one. Grades: 98%. CAS No. 160807-49-8. Molecular formula: C16H11N3O2. Mole weight: 277.28.
Indocyanine Green
Indocyanine Green is a tricarbocyanine type of dye with infrared absorbing property. Alternative Names: IR 125; Cardiogreen; Foxgreen; IC Green; 2-[7-[1,3-dihydro-1,1-dimethyl-3(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indoliumhydroxide, inner salt, sodium salt. CAS No. 3599-32-4. Molecular formula: C43H47N2NaO6S2. Mole weight: 774.96.
Indol-3-acetaldehyde
Indol-3-acetaldehyde (CAS# 2591-98-2 ) is a useful research chemical. Alternative Names: 1H-indole-3-acetaldehyde; Indoleacetaldehyde; 1H-Indol-3-ylacetaldehyde. Grades: 95 %. CAS No. 2591-98-2. Molecular formula: C10H9NO. Mole weight: 159.18.
Indole
Indole (CAS# 120-72-9) is a useful research chemical. Alternative Names: 1H-indole. Grades: 95 %. CAS No. 120-72-9. Molecular formula: C8H7N. Mole weight: 117.15.
Indole-3-acetaldehyde-sodium bisulfite addition compound (CAS# 20095-27-6) is a useful research chemical. Alternative Names: sodium;1-hydroxy-2-(1H-indol-3-yl)ethanesulfonate. Grades: ≥ 98 %. CAS No. 20095-27-6. Molecular formula: C10H10NNaO4S. Mole weight: 263.25.
Indoline
An indole derivative used in the preparation of various medicinal compounds such as potential α1-adrenoceptor (α1-AR) antagonists. Alternative Names: 2,3-dihydro-1H-indole. Grades: 98 %. CAS No. 496-15-1. Molecular formula: C8H9N. Mole weight: 119.16.
Indometacin sodium
Indomethacin sodium is the sodium salt of indomethacin, a non-selective, reversible, and competitive inhibitor of COX-1 and -2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Alternative Names: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid sodium salt. Grades: ≥98% (HPLC). CAS No. 74252-25-8. Molecular formula: C19H21ClNNaO7. Mole weight: 433.82.
INDOMETHACIN SODIUM
Indomethacin (Indometacin) sodium is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research. Alternative Names: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-aceticacisodiumsalt; 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-aceticacisodiumsalt; osmosin; sodium1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetate; sodiumindomethacin; INDOMETHACIN SODIUM; 1-(. Grades: 95%. CAS No. 7681-54-1. Molecular formula: C19H15ClNNaO4. Mole weight: 379.77.
an oxadiazine pesticide developed by DuPont that acts against lepidopteran larvae. Alternative Names: Methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate. Grades: > 95%. CAS No. 173584-44-6. Molecular formula: C22H17ClF3N3O7. Mole weight: 527.84.
Indoxacarb Impurity 8
an intermediate in the synthesis of Indoxacarb. Alternative Names: [4-(Trifluoromethoxy)phenyl]carbamic Acid Methyl Ester. Grades: > 95%. CAS No. 177905-10-1. Molecular formula: C9H8F3NO3. Mole weight: 235.16.
Inebilizumab
Inebilizumab is an anti-CD19 monoclonal antibody used to treat adults with neuromyelitis optica spectrum disorders (NMOSD). CAS No. 1299440-37-1.
Infliximab
Infliximab is a monoclonal antibody drug that is used for the treatment of rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, Crohn's disease, and ankylosing spondylitis. It binds to tumor necrosis factor alpha (TNF-α), which plays a role in the autoimmune reation. Infliximab may lead to fatal infections yet. Alternative Names: Immunoglobulin G, anti-(human tumor necrosis factor) (human-mouse monoclonal cA2 heavy chain), disulfide with human-mouse monoclonal cA2 light chain, dimer; Avakine; Remicade; Remsima. Grades: 95%. CAS No. 170277-31-3.
Ingavirin
Ingavirin is an inhibitor of influenza virus, thus it was used to treat acute respiratory infections and common cold. Alternative Names: Ingavirin;219694-63-0;Ingamine;IMIDAZOLYL ETHANAMIDE PENTANDIOIC ACID;pentanedioic acid imidazolyl ethanamide;4-{[2-(1H-imidazol-5-yl)ethyl]carbamoyl}butanoic acid;3CM03MUJ69;Pentanoic acid, 5-[[2-(1H-imidazol-4-yl)ethyl]amino]-5-oxo-;5-((2-(1H-Imidazol-5-yl)ethyl)amino)-5-oxopentanoic acid;4-[2-(1H-Imidazol-4-yl)-ethylcarbamoyl]-butyric acid;dicarbamin;vitaglutam;Pentanoic acid, 5-((2-(1H-imidazol-4-yl)ethyl)amino)-5-oxo-;5-[2-(1H-imidazol-5-yl)ethylamino]-5-oxopentanoic acid;AGN-PC-0MW29Y;UNII-3CM03MUJ69;SCHEMBL8282926;CHEMBL4297291;SCHEMBL18381264;5-(2-(1H-imidazol-4-yl)ethylamino)-5-oxopentanoic acid;DTXSID90433141;AKOS002807987;AKOS022996141;DB11944;HY-114784;CS-0064321;NS00072451;D11250;EN300-322394;F75163;IMIDAZOLYL ETHANAMIDE PENTANDIOIC ACID [WHO-DD];Q27257036;4-{[2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid;4-{[2-(1H-imidazol-5-yl)ethyl]carbamoyl}butanoicacid;6-(2-(1H-imidazol-4-yl)ethylamino)-5-oxohexanoic acid. CAS No. 219694-63-0. Molecular formula: C9H10FN3O3. Mole weight: 227.19.
Iniparib
BSI-201 is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair. PARP-1 catalyzes post-translational ADP-ribosylation of nuclear proteins and is activated by single-strand DNA (ssDNA) breaks. Uses: Poly(adp-ribose) polymerase inhibitors. Alternative Names: BSI-201; BSI201; BSI 201; NSC746045; NSC-746045; NSC 746045; ND-71677; NIBA; INO-2BA; SAR-240550; IND-71677. IND 71677; IND71677; Iniparib. Grades: 99.82%. CAS No. 160003-66-7. Molecular formula: C7H5IN2O3. Mole weight: 292.032.
inorganicbromidesresultingfrom
inorganicbromidesresultingfrom. CAS No. 24959-67-9. Molecular formula: Br-. Mole weight: 79.90.
Inosine 5'-diphosphate disodium salt
Inosine 5'-diphosphate disodium salt, a pivotal biochemical compound sought after in the biomedical industry, assumes an indispensable function in the generation and modulation of intracellular signaling molecules. Given its implication in cellular energy metabolism and nucleotide biosynthesis, this particular product finds application in ameliorating distinct metabolic disorders and neurodegenerative ailments. Alternative Names: Inosine 5'-(trihydrogen diphosphate), disodium salt; IDP disodium salt; Inosine 5'-diphosphate sodium salt; Inosine 5'-(trihydrogen diphosphate), sodium salt (1:2). Grades: 95%. CAS No. 54735-61-4. Molecular formula: C10H12N4Na2O11P2. Mole weight: 472.15.
Inosine 5'-monophosphate disodium salt
Disodium inosinate (E631) is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks. This salt is used as a flavor enhancer made from microbial fermentation growth media that are all-vegetable, usually consisting mainly of tapioca starch. Alternative Names: Disodium 5'-inosinate; Disodium inosinate; Sodium Inosine 5'-Phosphate (2:1); 5'-Inosinic Acid Disodium Salt; 5'-IMP Disodium Salt; Disodium 5'-IMP; Disodium 5'-Inosinate; Disodium IMP; Disodium Inosinate; Disodium Inosine 5'-Monophosphate; Disodium Inosine 5'-Phosphate; IMP Disodium Salt; Inosine 5'-Monophosphate Disodium Salt; Inosine 5'-Monophosphoric Acid Disodium Salt. Grades: ≥97% by HPLC. CAS No. 4691-65-0. Molecular formula: C10H11N4Na2O8P. Mole weight: 392.17.
Inositol nicotinate
Inositol nicotinate, with vasodilatory effect, is used in the study of Peripheral arterial disease (PAD). Alternative Names: Inositol niacinate; myo-Inositol hexanicotinate. CAS No. 6556-11-2. Molecular formula: C42H30N6O12. Mole weight: 810.72.
Inotersen
Inotersen is an antisense oligonucleotide (ASO) targeting transthyretin (TTR), which has potential use in the treatment of TTR amyloidosis (ATTR). Upon subcutaneous administration, inotersen targets and binds to messenger RNA (mRNA) for both variant and wild-type forms of TTR inside liver cells, thereby inhibiting translation of both mutant and wild-type TTR. Alternative Names: GSK-2998728; ISIS-420915. CAS No. 1492984-65-2. Molecular formula: C230H299N69O121P19S19Na19. Mole weight: 7600.8.
Inotersen sodium
Inotersen sodium, a 2'-O-methoxyethyl-modified antisense oligonucleotide, inhibits the production of transthyretin (TTR) protein by targeting the TTR RNA transcript and reduces the levels of the TTR transcript. Alternative Names: ISIS-420915 sodium; ISIS 420915 sodium; ISIS420915 sodium. Grades: 95%. CAS No. 1432726-13-0.
Inotodiol
Inotodiol is a natural product found in Inonotus obliquus. It has significant anti-tumor and anti-tumor promoting activities, including human cervical cancer. Alternative Names: (22R)-5α-Lanosta-8,24-diene-3β,22-diol; Lanosta-8,24-diene-3,22-diol, (3β,22R)-; (3β,22R)-Lanosta-8,24-diene-3,22-diol; lanosta-8,24-diene-3β,22R-diol. Grades: ≥90%. CAS No. 35963-37-2. Molecular formula: C30H50O2. Mole weight: 442.73.
Inotuzumab ozogamicin
Inotuzumab ozogamicin is a targeted therapy used in the treatment of certain types of leukemia. Inotuzumab ozogamicin is an antibody-drug conjugate (ADC) that combines a monoclonal antibody targeting CD22, a protein expressed on the surface of B cells, with a cytotoxic agent, calicheamicin. The antibody component of inotuzumab ozogamicin binds to CD22 on the surface of cancerous B cells, allowing the cytotoxic agent to be internalized into the cells. Once inside, calicheamicin induces double-stranded DNA breaks, leading to cell death. Inotuzumab ozogamicin is indicated for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). It is used when the disease has not responded to previous treatments or has returned after initial remission. Uses: The treatment of acute lymphoblastic leukemia (all). Alternative Names: Immunoglobulin G4 (anti-(human CD22 (antigen)) (human-mouse monoclonal G544 heavy chain)), disulfide with human-mouse monoclonal G544 κ-chain, dimer, methyl N-[(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyranos. CAS No. 635715-01-4. Molecular formula: C73H96IN6O25S3. Mole weight: 1680.67.
Ins(1,3,4,5)P4 Biotin
Ins(1,3,4,5)P4 Biotin is an analog of Ins(1,3,4,5)P4 labelled with biotin through a three-carbon linker at the 1-position on the inositol ring. Inositol phosphates are important signaling molecules involved in numerous cellular functions. Alternative Names: Inositol 1,3,4,5-tetrakisphosphate Biotin. Grades: >95%. Molecular formula: C25H41N4Na7O21P4S. Mole weight: 1050.49.
INS37217
INS-37217, also known as Denufosol, is a long- acting P2Y2 receptor agonist potentially for the treatment of cystic fibrosis. INS-37217 exhibits an EC50 of ~10 μM for P2Y2 receptor activation. Alternative Names: INS37217; INS 37217; INS-37217; Uridine 5'-(pentahydrogen tetraphosphate), P'''→5'-ester with 2'-deoxycytidine, sodium salt (1:4). CAS No. 318250-11-2. Molecular formula: C18H27N5Na4O21P4. Mole weight: 865.28.
INSULIN CHAIN A, OXIDIZED AMMONIUM SALT
INSULIN CHAIN A, OXIDIZED AMMONIUM SALT. CAS No. 77282-71-4. Molecular formula: C97H163N29O46S4. Mole weight: 2599.76.
Insulin Glargine
Insulin Glargine is a long-acting insulin used in the treatment of diabetes. It helps control blood sugar levels by mimicking the actions of naturally produced insulin in the body. Uses: Hypoglycemic agents. Alternative Names: A21-Gly-B31-Arg-B32-Arg-insulin; Insulin, glycyl(A21)-arginyl(B31,B32)-. Grades: > 95%. CAS No. 160337-95-1. Molecular formula: C267H404N72O78S6. Mole weight: 6063.
Insulin Glargine Metabolite M1
a metabolite of Insulin Glargine. Grades: > 95%. Mole weight: 5750.64.
Insulin Glargine Metabolite M2
a metabolite of Insulin Glargine. Grades: > 95%. Mole weight: 5649.53.
Insulin (swine) is a polypeptide hormone that regulates glucose metabolism in pancreatic islet B cells. Alternative Names: Insulin (ox), 8A-L-threonine-10A-L-isoleucine-; L-Alanine, L-phenylalanyl-L-valyl-L-asparaginyl-L-glutaminyl-L-histidyl-L-leucyl-L-cysteinylglycyl-L-seryl-L-histidyl-L-leucyl-L-valyl-L-α-glutamyl-L-alanyl-L-leucyl-L-tyrosyl-L-leucyl-L-valyl-L-cysteinylglycyl-L-α-glutamyl-L-arginylglycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-, cyclic (7→7'),(19→20')-bis(disulfide) with glycyl-L-isoleucyl-L-valyl-L-α-glutamyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-L-α-glutamyl-L-asparaginyl-L-tyrosyl-L-cysteinyl-L-asparagine cyclic (6'→11')-disulfide; Actrapid MC; Hog insulin; Insulin (Alopex lagopus); Insulin (Canis familiaris); Insulin (Physeter catodon); Insulin (pig); Insulin (porcine); Insulin Novo Actrapid MC; Neutral Insulin; Pensulin SR; Pig insulin; Porcine insulin; Swine insulin; H-Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala-OH.H-Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn-OH (Disulfide bridge: Cys7-Cys7', Cys19-Cys20', Cys6'-Cys11'). Grades: 95%. CAS No. 12584-58-6. Molecular formula: C256H381N65O76S6. Mole weight: 5777.54.
INT-767
INT-767, a steride compound, has been found to be a inhibitor of FXR and TGF5 and could have probable effect against some liver and metabolic diseases. It was just planed a Phase II trial for Hepatic fibrosis. IC50: 30 nM(EC50, FXR), 630 nM(EC50, TGR5). Uses: Int-767 has been found to be a inhibitor of fxr and tgf5 and could have probable effect against some liver and metabolic diseases. Alternative Names: INT-767; INT 767; INT767; CS-5007; CS 5007; CS5007; HY-12434; HY 12434; HY12434; Sulfuric acid sodium 3alpha,7alpha-dihydroxy-6alpha-ethyl-24-nor-5beta-cholane-23-yl ester salt. Grades: 98%. CAS No. 1000403-03-1. Molecular formula: C25H43NaO6S. Mole weight: 494.66.
Integrin Antagonists 27
Integrin Antagonists 27, as s novel anticancer agent., is a small molecule integrin αvβ3 antagonist. Uses: Anticancer agent. Alternative Names: MDK-4976; Integrin Antagonist 27; MDK4976; MDK 4976; 3-{2-[(Z)-(1-{2-[(4-Methylphenyl)amino]-2-oxoethyl}-2,5-dioxo-4-imidazolidinylidene)methyl]-1H-pyrrol-1-yl}benzoic acid. Grades: ≥96%. CAS No. 593274-97-6. Molecular formula: C24H20N4O5. Mole weight: 444.44.
interferon β-1b
interferon β-1b. Grades: 95%. CAS No. 145155-23-3. Molecular formula: C903H1399N245O252S5.
Intralipid
Intralipid. CAS No. 68890-65-3.
Inulin
Inulin (Inulin and sodium chloride) is a starch found in the tubers and roots of many plants, classified as a fructosan. Inulin is used as an adjuvant to enhance vaccine efficacy against influenza, hepatitis B, West Nile virus, Japanese encephalitis, human immunodeficiency virus, SARS, and anthrax. Alternative Names: β-d-[2→1] poly(fructo-furanosyl) α-d-glucose; Poly-b-(2-1)-fructofuranose; Polyfructose; a-D-glucopyranosyl-[b-D-fructofuranosyl](n-1)-D-fructofuranosides; GpyFn; Advax; Advax D; Agave Inulin; Alant starch; Alantin; Beneo; CBP Inulin; Dahlin; Fibruline; Fibrulose; Inulin Fib97; LV 110; Oliggo-Fiber F 97; P95 FOS; Prebiofeed; Raftifeed IPE; Raftifeed IPS; Raftiline; Sinantrin; Synantherin; Ticaloid LC-CSR 2. Grades: 90%. CAS No. 9005-80-5. Molecular formula: C6nH10n+2O5n+1.