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Insulin (human)
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Uses: Api. Synonyms: Recombinant human insulin; Insulin human; H-Phe-Val-Asn-Gln-His-Leu-Cys(1)-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys(2)-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH.H-Gly-Ile-Val-Glu-Gln-Cys(3)-Cys(1)-Thr-Ser-Ile-Cys(3)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(2)-Asn-OH; L-phenylalanyl-L-valyl-L-asparagyl-L-glutaminyl-L-histidyl-L-leucyl-L-cysteinyl-glycyl-L-seryl-L-histidyl-L-leucyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-tyrosyl-L-leucyl-L-valyl-L-cysteinyl-glycyl-L-alpha-glutamyl-L-arginyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-L-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-L-isoleucyl-L-valyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-asparagyl-L-tyrosyl-L-cysteinyl-L-asparagine (6'->11')-disulfide. Grades: ≥99% by HPLC. CAS No. 11061-68-0. Molecular formula: C257H383N65O77S6. Mole weight: 5807.57.
iPr-Pac-dG-Me Phosphoramidite
iPr-Pac-dG-Me Phosphoramidite is a chemical reagent used in the production of modified DNA sequences for biological and medical research. This specific phosphoramidite is often incorporated into synthetic DNA strands for use in gene therapy and vaccination research, as well as for drug development targeting specific diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-Guanosine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C49H59N6O9P. Mole weight: 907.01.
Isocytidine
An isomer of Cytidine, a constituent of nucleic acid. It is converted to isocytosine and uracil during metabolism in Escherichia coli. Synonyms: 2-Amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone; 1-(2-Amino-4-oxo-1(4H)-pyrimidinyl)-1-deoxy-beta-D-ribofuranose; 2-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-4(1H)-one. Grades: ≥95%. CAS No. 489-59-8. Molecular formula: C9H13N3O5. Mole weight: 243.22.
Iso Desloratadine Hydrochloride
Cas No. 432543-89-0.
Iso-GTP
Iso-GTP, a renowned biomedical compound, is eagerly utilized as a substrate to gauge the prowess of GTPases and their ilk. Researchers find it to be an excellent propellant to probe into the mysteries of cellular signal pathways associated with the regulation of said activity. Synonyms: Isoguanosine-5'-Triphosphate; 2-hydroxy-ATP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O14P3. Mole weight: 523.1.
Isoguanosine Hydrate
A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5'-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water. Synonyms: 2-Hydroxy adenosine hydrate; 1,2-Dihydro-2-oxo-adenosine Hydrate; Crotonosid Hydrate; Isoguanine riboside Hydrate; NSC 1216 Hydrate; 2,3-Dihydro-2-oxoadenosine Hydrate; 6-Amino-9-β-D-ribofuranosyl-9H-Purin-2-ol Hydrate. Grades: ≥95%. CAS No. 359436-55-8. Molecular formula: C10H13N5O5. Mole weight: 283.24.
Isothiazolo[4,3-d]pyrimidin-7(6H)-one, 5-amino-3-β-D-ribofuranosyl- is an exceedingly proficient antiviral compound employed for the research of infectious diseases instigated by distinctive ribonucleic acid (RNA) viruses such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Its mechanism of action substantiates in the inhibition of viral RNA replication, thereby constricting viral dissemination and studying the viral burden in infected individuals. CAS No. 1821192-01-1. Molecular formula: C10H12N4O5S. Mole weight: 300.29.
Isothiazolo[4,3-d]pyrimidine-7(6H)-thione, 3-[2,3,5-tris-O-(phenylmethyl)-β-D-ribofuranosyl]- is an exceptionally efficacious antiviral compound employed within the biomedical field for studying viral infections. It exerts its inhibitory prowess upon the replication of viral RNA, duly quelling the surging tide of viral proliferation. Synonyms: 3-[2,3,5-Tris-O-(phenylmethyl)-β-D-ribofuranosyl]isothiazolo[4,3-d]pyrimidine-7(6H)-thione. CAS No. 1821191-95-0. Molecular formula: C31H29N3O4S2. Mole weight: 571.71.
Isowyosine
Isowyosine is a remarkable and efficacious antiviral compound, exhibiting immense promise for the research of diverse viral afflictions, ranging from the notorious influenza to the formidable hepatitis. By virtue of its intricate mechanism of action,owyosine proficiently impedes the pernicious process of viral replication. Synonyms: 7-Methylwyosine; 3-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6,7-dimethyl-3H-imidazo[1,2-a]purin-9(4H)-one; 3,4-Dihydro-6,7-dimethyl-3-β-D-ribofuranosyl-9H-imidazo[1,2-a]purin-9-one; imG2; 6,7-Dimethyl-3-(β-D-ribofuranosyl)-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one. Grades: ≥95% by HPLC. CAS No. 577773-09-2. Molecular formula: C14H17N5O5. Mole weight: 335.32.
Jingzhaotoxin III
Jingzhaotoxin III is a selective blocker of NaV1.5 channels with IC50 value of 348 nM. It is selective for NaV1.5 channels and shows no effect on other isoforms. It inhibits the activation of cardiac sodium channels by binding to the NaV1.5 S3-S4 linker of domain II. It has no effect on sodium channels in dorsal root ganglion neurons. Synonyms: H-Asp-Gly-Glu-Cys(1)-Gly-Gly-Phe-Trp-Trp-Lys-Cys(2)-Gly-Arg-Gly-Lys-Pro-Pro-Cys(3)-Cys(1)-Lys-Gly-Tyr-Ala-Cys(2)-Ser-Lys-Thr-Trp-Gly-Trp-Cys(3)-Ala-Val-Glu-Ala-Pro-OH; L-alpha-aspartyl-glycyl-L-alpha-glutamyl-L-cysteinyl-glycyl-glycyl-L-phenylalanyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-glycyl-L-arginyl-glycyl-L-lysyl-L-prolyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-lysyl-glycyl-L-tyrosyl-L-alanyl-L-cysteinyl-L-seryl-L-lysyl-L-threonyl-L-tryptophyl-glycyl-L-tryptophyl-L-cysteinyl-L-alanyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-proline (4->19),(11->24),(18->31)-tris(disulfide). Grades: >98%. CAS No. 925463-91-8. Molecular formula: C174H241N47O46S6. Mole weight: 3918.44.
JIP-1 (153-163)
JIP-1 (153-163) has been found to be a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Synonyms: TI-JIP. Grades: >98%. CAS No. 438567-88-5. Molecular formula: C61H104N20O14. Mole weight: 1341.6.
K 41498
K 41498 is a potent and highly selective CRF2 receptor antagonist. Its Ki values are 425, 0.66 and 0.62 nM for human CRF1, CRF2α and CRF2β receptors respectively. It prevents sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. It blocks urocortin-induced hypotension following systemic administration in rats in vivo and is used to treat hypertension in rodents. Synonyms: D-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-norleucyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparaginyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-α-aspartyl-L-threonyl-L-Isoleucinamide. Grades: >98%. CAS No. 434938-41-7. Molecular formula: C162H276N48O46. Mole weight: 3632.26.
Kaliotoxin
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activated K+ channels. Grades: 98 % (HPLC). CAS No. 145199-73-1. Molecular formula: C171H283N55O49S8. Mole weight: 4149.94.
Kassinin
Kassinin, a tachykinin peptide derived from the Kassina frog, is secreted as a defense response, and is involved in neuropeptide signalling and shows selectivity for NK2 over NK1 in mammals. Uses: Neurotransmitter agents. Synonyms: CID45749; Kassinin. CAS No. 63968-82-1. Molecular formula: C59H95N15O18S. Mole weight: 1334.54.
Katacalcin
Katacalcin is a second potent plasma calcium-lowering peptide that may be a useful marker for the detection of medullary thyroid carcinoma. Uses: Calcium-regulating hormones and agents. Synonyms: PDN 21; H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH; L-alpha-aspartyl-L-methionyl-L-seryl-L-seryl-L-alpha-aspartyl-L-leucyl-L-alpha-glutamyl-L-arginyl-L-alpha-aspartyl-L-histidyl-L-arginyl-L-prolyl-L-histidyl-L-valyl-L-seryl-L-methionyl-L-prolyl-L-glutaminyl-L-asparagyl-L-alanyl-L-asparagine; Calcitonin C-Terminal Flanking Peptide (human). Grades: ≥95%. CAS No. 85916-47-8. Molecular formula: C97H154N34O36S2. Mole weight: 2436.59.
K-(D-1-Nal)-FwLL-NH2
K-(D-1-Nal)-FwLL-NH2 is a potent and high affinity inverse ghrelin receptor inverse agonist. Its Ki values are 31 and 4.9 nM in HEK293T and COS7 cells respectively. It blocks ghrelin receptor-mediated G13- and Gq-dependent signaling pathways. Synonyms: L-Lysyl-3-(1-naphthalenyl)-D-alanyl-L-phenylalanyl-D-tryptophyl-L-leucyl-L-leucinamide; K-(D-1-Nal)-FwLL-NH2; K (D 1 Nal) FwLL NH2. Grades: >98%. CAS No. 1394288-22-2. Molecular formula: C51H67N9O6. Mole weight: 902.13.
Kemptide
Kemptide, a synthetic heptapeptide, acts as a specific substrate for cAMP-dependent protein kinase (PKA) and is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. Synonyms: H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH; L-leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucyl-glycine; (5S,8S,11S,14S,17S,20S)-20-amino-14,17-bis(3-guanidinopropyl)-8-(hydroxymethyl)-5-isobutyl-11,22-dimethyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazatricosan-1-oic acid. Grades: ≥97% by HPLC. CAS No. 65189-71-1. Molecular formula: C32H61N13O9. Mole weight: 771.91.
Kemptide Phospho-Ser5
Kemptide (Phospho-Ser5), a phosphate acceptor peptide, serves as a specific substrate for cAMP-dependent protein kinase (PKA). Synonyms: Leu-Arg-Arg-Ala-pSer-Leu-Gly; H-Leu-Arg-Arg-Ala-Ser(PO3H2)-Leu-Gly-OH; L-leucyl-L-arginyl-L-arginyl-L-alanyl-O-phosphono-L-seryl-L-leucyl-glycine; phosphokemptide; Kinase Domain of Pyruvate Kinase porcine. Grades: ≥95%. Molecular formula: C32H62N13O12P. Mole weight: 851.89.
Kinetensin
Kinetensin (human) is an endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It increases vascular permeability and releases histamine from rat mast cells. It induces histamine release from rat peritoneal mast cells with ED50 value of 10 mM in vitro. Synonyms: Kinetensin (human); Neurotensin-related peptide; H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH; L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine. Grades: ≥95%. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.38.
Kinetin riboside-5'-diphosphate sodium salt
Kinetin riboside-5'-monophosphate sodium salt
Kinetin riboside-5'-monophosphate sodium salt, a biomedical compound renowned for its efficacy in combating an array of ailments, emerges as an invaluable panacea for age-related afflictions. Devotedly addressing the challenging sphere of neurodegenerative maladies encompassing Alzheimer's and Parkinson's diseases, this therapeutic treasure trove amalgamates potent antioxidative and anti-inflammatory attributes. Consequently, it orchestrates a symphony of cellular revitalization, ushering in a respite from the ravages of time-induced degeneration. Synonyms: 6-furfurylamino-9-b-D-ribofuranosylpurine-5'-monophosphate disodium monohydrate; [5-[6-(2-furylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid. Grades: ≥ 97% (HPLC). CAS No. 13484-67-8. Molecular formula: C15H16N5Na2O8P·H2O. Mole weight: 489.29.
Kinetin Riboside-5'-monophosphorodichloridate
Kinetin Riboside-5'-monophosphorodichloridate is an intermediate used in the synthesis of Kinetin Riboside-5'-monophosphate, which can be used in pharmacological activity and therapeutic use for structure-related anticancer activity of natural cytokinins. Along with other adenosine derivatives, it can also be used in biological study for manufacture of pharmaceutical formulations for treatment against various parasites, mycoplasmas, other indications and other infections and human immunodeficiency virus inhibition. Molecular formula: C15H16Cl2N5O6P. Mole weight: 464.2.
Kinetin riboside-5'-triphosphate sodium salt
Kisspeptin 234
Kisspeptin 234 is a kisspeptin-10 analog and is used as a kisspeptin receptor antagonist. It inhibits kisspeptin-10 stimulation of inositol phosphate with IC50 value of 7 nM and release of gonadotrophin-releasing hormone. Synonyms: Ac-D-Ala-Asn-Trp-Asn-Gly-Phe-Gly-D-Trp-Arg-Phe-NH2; N-acetyl-D-alanyl-L-asparagyl-L-tryptophyl-L-asparagyl-glycyl-L-phenylalanyl-glycyl-D-tryptophyl-L-arginyl-L-phenylalaninamide. Grades: >98%. CAS No. 1145998-81-7. Molecular formula: C63H78N18O13. Mole weight: 1295.42.
KRpep-2d
KRpep-2d is a K-Ras(G12D) selective inhibitory cyclic peptide that has the potential as the treatment of cancers expressing K-Ras(G12C) mutant. Synonyms: s8499. Molecular formula: C108H182N44O25S2. Mole weight: 2561.01.
KYL
KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half life in cell culture media. It has the neuroprotective effect. Synonyms: H-Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu-OH; L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine; HY-P2264. Grades: ≥95%. CAS No. 676657-00-4. Molecular formula: C74H108N14O17. Mole weight: 1465.75.
L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid (CAS# 42438-90-4) is a useful research chemical. Synonyms: L-Tpi-OH; (S)-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid. Grades: ≥ 98 %. CAS No. 42438-90-4. Molecular formula: C12H12N2O2. Mole weight: 216.23.
L-4-Oxalysine hydrochloride
L-4-oxalysine is a natural product isolated from a new species of Streptomyces roseoÍiridofuscus n.sp. in China. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma. Synonyms: (2S)-2-amino-3-(2-aminoethoxy)propanoic acid;hydrochloride. CAS No. 118021-35-5. Molecular formula: C5H13ClN2O3. Mole weight: 184.62.
L-5-methyluridine
L-5-Methyluridine is a nucleoside analogue employed, serving as a potent therapeutic compound against afflictions caused by viral compounds, including hepatitis B and hepatitis C. It operates by impeding viral replication mechanisms, thereby exhibiting remarkable antiviral prowess. This specific product holds immense potential for application within the realms of antiviral drug investigation, as well as the examination of nucleoside metabolism intricacies and nucleic acid synthesis processes. Synonyms: beta-L-ribofuranosyl thymine; 5-methyl-1-(beta-L-ribofuranosyl)uracil; L-5-Me-rU; 1-beta-l-ribofuranosylthymine; 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-beta-L-ribofuranosyl-; 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; L-5-Me-Uridine. Grades: ≥97% by HPLC. CAS No. 642082-80-2. Molecular formula: C10H14N2O6. Mole weight: 258.23.
L-Adenosine 5'-triphosphate sodium salt
L-Adenosine 5'-triphosphate sodium salt, a pivotal biomolecule extensively utilized in the biomedical sector, emerges as a fundamental energy contributor in cellular mechanisms. Its multifaceted involvement encompasses metabolic facilitation, catalyzing enzymatic reactions, and mediating signal transduction pathways. Its indispensability becomes evident when considering its incorporation in pharmaceutical compositions targeting neurological afflictions, cardiac ailments, and maladies attributable to compromised energy metabolism pathways. Molecular formula: C10H12N5O13P3Na4. Mole weight: 595.11.
LAH4
LAH4, a-helix of the amphipathic peptide antibiotic, strongly interacts with phospholipid membranes, exhibiting in vitro transfection efficiency. The LAH4 family of histidine-rich peptides exhibits potent antimicrobial and DNA transfection activities, both of which require interactions with cellular membranes. Synonyms: LAH 4; LAH-4; Lys-Lys-Ala-Leu-Leu-Ala-Leu-Ala-Leu-His-His-Leu-Ala-His-Leu-Ala-Leu-His-Leu-Ala-Leu-Ala-Leu-Lys-Lys-Ala; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-alanyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-histidyl-L-leucyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-lysyl-L-alanine. Grades: ≥95%. Molecular formula: C132H228N38O27. Mole weight: 2779.46.
L-Alanine benzyl ester p-toluenesulfonate salt
A benzoxazine derivatives as modulators of chemokine receptors for treatment of inflammatory and immunoregulatory diseases. Synonyms: beta-Alanine benzyl ester p-toluenesulfonate. Grades: ≥ 99% (HPLC). CAS No. 42854-62-6. Molecular formula: C10H13NO2.C7H8O3S. Mole weight: 351.41.
L-Allo-isoleucine
L-Allo-isoleucine, an amino acid compound, has been found to be probably significant in the study of modulating of blood sugar. Synonyms: L-allo-Isoleucine; L-Alloisoleucine; (2S,3R)-2-amino-3-methylpentanoic acid; Alloisoleucine; Allo-Isoleucine. Grades: 98%. CAS No. 1509-34-8. Molecular formula: C6H13NO2. Mole weight: 131.18.
L-Allylglycine is a glycine derivative that acts as an inhibitor of glutamate decarboxylase. L-Allylglycine blocks the synthesis of GABA, inducing panic-like responses in rat models. Synonyms: (S)-2-aminopent-4-enoic acid; (S)-(-)-2-Amino-4-pentenoic acid. Grades: ≥ 98% (HPLC, Chiral purity). CAS No. 16338-48-0. Molecular formula: C5H9NO2. Mole weight: 115.1.
Lamivudine 5'-monophosphate sodium salt
Lamivudine 5'-monophosphate sodium salt is a fundamental and indispensable biomedical compound employed in the research of HIV/AIDS. Serving as a nucleoside analogue reverse transcriptase inhibitor, this product proficiently impedes viral replication. Its mechanism of action entails obstructing the enzyme accountable for the synthesis of viral DNA is accordingly inhibiting viral dissemination. Synonyms: 4-Amino-1-[(2R,5S)-2-[(phosphonooxy)methyl]-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone soidum salt. Molecular formula: C8H11N3O6PSNa. Mole weight: 331.22.
Lamivudine 5'-monophosphate triethyammonium salt
Lamivudine 5'-monophosphate triethyammonium salt is an antiretroviral compound, aiding in studying human immunodeficiency virus (HIV) infections and acquired immunodeficiency syndrome (AIDS). This salt form of Lamivudine 5'-monophosphate enhances its stability and bioavailability. Molecular formula: C8H12N3O6PS. Mole weight: 309.23.
Lamivudine-5'-triphosphate tetratriethylammonium salt
Lamivudine-5'-triphosphate tetratriethylammonium salt is an indispensible biomedical compound, used for designed nucleoside reverse transcriptase inhibitor. It aids in the research of HIV (Human Immunodeficiency Virus). Molecular formula: C32H74N7O12P3S. Mole weight: 873.96.
Lamivudine 5'-triphosphate triethylammonium salt
Lamivudine 5'-triphosphate triethylammonium salt is an indispensable compound acting as an antiviral substance for studying the deleterious HIV-1 and hepatitis B virus-induced infections resonates. It can thwart viral reverse transcriptase. Grades: ≥ 98% (HPLC). Molecular formula: C20H46N5O12P3S. Mole weight: 673.59.
Lantibiotic subtilin
Lantibiotic subtilin is an antibacterial peptide isolated from Bacillus subtilis. Synonyms: Trp-Lys-Ser-Glu-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Val-Thr-Gly-Ala-Leu-Gln-Thr-Cys-Phe-Leu-Gln-Thr-Leu-Thr-Cys-Asn-Cys-Lys-Ile-Ser-Lys. CAS No. 1393-38-0. Molecular formula: C148H227N39O38S5. Mole weight: 3320.94.
L-Arginine hydrochloride
L-Arginine hydrochloride is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Protein supplement in health care products. Uses: Ingredient of health care products. Synonyms: Arginine Hydrochloride; L-Arginine monohydrochloride; L-Arginine HCl; H-Arg-OH.HCl; (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid hydrochloride. Grades: 98%. CAS No. 1119-34-2. Molecular formula: C6H15ClN4O2. Mole weight: 210.662.
Lariatin A
Lariatin A is an antimycobacterial lasso peptide isolated from Rhodococcus jostii. Lariains A has inhibitory effect on the growth of Mycobacterium smegmatis with MIC value of 3.13 mg/ml in agar dilution method. Synonyms: Peptide K01-B0171-B; N(1)Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu(1)-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Pro-OH; L-Proline, glycyl-L-seryl-L-glutaminyl-L-leucyl-L-valyl-L-tyrosyl-L-arginyl-L-α-glutamyl-L-tryptophyl-L-valylglycyl-L-histidyl-L-seryl-L-asparaginyl-L-valyl-L-isoleucyl-L-lysyl-, (8?1)-lactam. Grades: ≥95%. CAS No. 732286-09-8. Molecular formula: C94H143N27O25. Mole weight: 2051.31.
Lauroyl coenzyme A potassium salt
Lauroyl coenzyme A potassium salt is an indispensable constituent aiding in studying ailments ranging from cancer to metabolic and neurodegenerative disorders. Molecular formula: C33H58N7O17P3S·3K. Mole weight: 1067.13.
L-β-Homoproline hydrochloride
L-β-Homoproline hydrochloride (CAS# 53912-85-9) is the hydrochloride salf from of (S)-2-Pyrrolidineacetic Acid (P997905), a starting material for GABA inhibitors. Synonyms: L-β-HomoPro-OH HCl; (S)-2-(2-Pyrrolidinyl)acetic acid hydrochloride; (S)-Homoproline hydrochloride; H-Pro-OH HCl. Grades: ≥ 98 %. CAS No. 53912-85-9. Molecular formula: C6H11NO2·HCl. Mole weight: 165.66.
L-DABA
L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50 > 500 μM) with antitumor activity in vivo and in vitro. Synonyms: (2S)-2,4-diaminobutanoic acid; 2,4-diaminobutyric acid; 2,4-diaminobutyric acid dihydrochloride, (+-)-isomer; 2,4-diaminobutyric acid dihydrochloride, (S)-isomer; 2,4-diaminobutyric acid monohydrochloride, (+-)-isomer; 2,4-diaminobutyric acid monohydrochloride, (S)-isomer; 2,4-diaminobutyric acid, (+)-isomer; 2,4-diaminobutyric acid, (+-)-isomer; 2,4-diaminobutyric acid, (R)-isomer; 2,4-diaminobutyric acid, (S)-isomer; L-2,4-diaminobutyric acid. CAS No. 1758-80-1. Molecular formula: C4H10N2O2. Mole weight: 118.13.
Leptin Fragment 116-130 Amide mouse
A synthetic leptin peptide fragment. Synonyms: LEP 116-130. Grades: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73.
[Leu5]-Enkephalin
[Leu5]-Enkephalin is an endogenous opioid agonist peptide with morphine-like activity. It inhibits electrically stimulated contractions in mouse vas deferens (IC50 = 11.4 nM). Synonyms: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin; H-Tyr-Gly-Gly-Phe-Leu-OH; YGGFL; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine. Grades: ≥95%. CAS No. 58822-25-6. Molecular formula: C28H37N5O7. Mole weight: 555.62.
[Leu5]-Enkephalin, amide
[Leu5]-Enkephalin, amide is a δ opioid receptor agonist peptide. Synonyms: Leu-Enkephalin amide; Leucine enkephalinamide; Enkephalinamide-leu; H-Tyr-Gly-Gly-Phe-Leu-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucinamide; YGGFL. Grades: ≥95%. CAS No. 60117-24-0. Molecular formula: C28H38N6O6. Mole weight: 554.64.
Leu-AMC HCl
L-Leucine 7-Amido-4-methylcoumarin Hydrochloride is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released. Synonyms: L-Leucine-AMC.HCl. Grades: ≥ 99% (HPLC). CAS No. 62480-44-8. Molecular formula: C16H21ClN2O3. Mole weight: 324.80.
Leu-AMS
Leu-AMS, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM and inhibits the growth of bacteria. Synonyms: 5'-[[(2S)-2-Amino-4-methyl-1-oxopentyl]sulfamate]adenosine. CAS No. 288591-93-5. Molecular formula: C16H25N7O7S. Mole weight: 459.48.
Leupeptin hemisulfate
Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases. Synonyms: Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfat. Grades: >98%. CAS No. 103476-89-7. Molecular formula: C20H38N6O4.1/2(H2SO4). Mole weight: 475.04.
Levovirin
Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia. Synonyms: 1-β-L-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; ICN 17261; L-Ribavirin. CAS No. 206269-27-4. Molecular formula: C8H12N4O5. Mole weight: 244.2.
L-Glutamic acid-[1,2-13C2]
L-Glutamic acid-[1,2-13C2] is a labelled L-Glutamic acid. Glutamic acid is a non-essential amino acid that acts as an excitatory neurotransmitter in the CNS. Synonyms: (2R)-2-aminopentanedioic acid-13C2. Grades: 98% by HPLC; 99% atom 13C. Molecular formula: C3[13C]2H9NO4. Mole weight: 149.11.
L-Glutamic Acid Monosodium Salt
Sodium Glutamate is an agonist at kainate, quisqualate and NMDA receptors. Synonyms: L-Glutamic Acid Monosodium Salt; Monosodium L-Glutamate; MSG. CAS No. 142-47-2. Molecular formula: C5H8NNaO4. Mole weight: 169.11.
L-homoarginine
L-homoarginine is a non-essential and non-proteinogenic amino acid, and acts as a competitive substrate for nitric oxide synthase (NOS), whereas asymmetric dimethylarginine (ADMA) is a NOS inhibitor. It is also a human arginase inhibitor. Synonyms: L-Lysine, N6-(aminoiminomethyl)-; Lysine, N6-amidino-; Lysine, N6-amidino-, L-; N6-(Aminoiminomethyl)-L-lysine; Homo-L-arginine; Homoarginine; NSC 27429; NSC 88868; N6-carbamimidoyl-L-lysine. Grades: ≥95%. CAS No. 156-86-5. Molecular formula: C7H16N4O2. Mole weight: 188.23.
L-Homoarginine hydrochloride
L-Homoarginine is an alkaline phosphatase inhibitor found in blood, cerebrospinal fluid (CSF), and urine, as well as in human intestine and testes tissues. L-Homoarginine also acts as a substrate of CAT1, CAT2A and CAT2B, and CAT1 is a key site with regard to physiological relevance and interactions with related substrates such as L-arginine. Synonyms: NSC 145416; (S)-2-Amino-6-guanidinohexanoic acid hydrochloride. Grades: ≥95%. CAS No. 1483-01-8. Molecular formula: C7H16N4O2·HCl. Mole weight: 224.7.
L-Homoproline ethyl ester hydrochloride
L-Homoproline ethyl ester hydrochloride (CAS# 123495-48-7) is a useful research chemical. Synonyms: H-homoPro-OEt HCl; H-Pic(2)-OEt HCl; (S)-Piperidine-2-carboxylic acid ethyl ester hydrochloride. Grades: ≥ 98 % (HPLC). CAS No. 123495-48-7. Molecular formula: C8H16ClNO2. Mole weight: 193.68.
LHRH (chicken)
It is a luteinizing hormone-releasing hormone (LHRH) that stimulates the anterior pituitary to release gonadotropins, thereby regulating reproductive function. Synonyms: H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-NH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-glycyl-L-leucyl-L-glutaminyl-L-prolyl-glycinamide; [Gln8]-C517 (LH-RH), chicken; 8-Glutamine-LHRH; GNRH, Chicken I; 8-Gln-LHRH; LHRH-I; pGlu-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-NH2. Grades: 95%. CAS No. 47922-48-5. Molecular formula: C54H71N15O14. Mole weight: 1154.23.
L-Isoleucinol (CAS# 24629-25-2) is a useful research chemical. Synonyms: H-Ile-ol; (2S,3S)-2-Amino-3-methyl-1-pentanol; H-Isoleucinol; L-(+)-Isoleucinol. Grades: ≥ 99 % (Assay). CAS No. 24629-25-2. Molecular formula: C6H15NO. Mole weight: 117.2.
L-Leucinol
A reversible inhibitor of protein synthesis and starting material for the synthesis of aminopeptidase N and phospholipase A2 inhibitors. Synonyms: (S)-(+)-Leucinol; H-Leucinol; L-(+)-Leucinol; (2S)-2-amino-4-methylpentan-1-ol. CAS No. 7533-40-6. Molecular formula: C6H15NO. Mole weight: 117.2.
L-Lysine 7-amido-4-methylcoumarin, acetate salt is a substrate for aminopeptidase b. Upon cleavage of aminopeptidase b a blue fluorescent solution results. It can also be used as analyte in analytical study for enhanced extraction of amino compounds using dicyclohexyl-18-crown-6 as a ligand in an aqueous two-phase system. Synonyms: L-Lysine-AMC acetate. CAS No. 201853-23-8. Molecular formula: C18H25N3O5. Mole weight: 363.41.
L-Norvalinol (CAS# 22724-81-8) is a useful research chemical. Synonyms: H-Nva-ol; (S)-2-Amino-1-pentanol; (S)-2-Aminopentan-1-ol; (2S)-2-aminopentan-1-ol; (S)-(+)-2-Amino-1-pentanol. CAS No. 22724-81-8. Molecular formula: C5H13NO. Mole weight: 103.17.
Long Trebler Phosphoramidite
Long Trebler Phosphoramidite - a molecular entity essential for oligonucleotide synthesis, particularly longitudinal strands, vital for biomedicinal research. Its application spans the spectrum of drug R&D, including genetic disorders such as AIDS, autoimmune diseases, and cancer treatment. Synonyms: Tris-2, 2, 2-[3- (4, 4'-dimethoxytrityloxy) propyloxymethyl]methyleneoxypropyl-[ (2-cyanoethyl) - (N, N-diisopropyl) ]-phosphoramidite. Molecular formula: C89H107N2O15P. Mole weight: 1475.78.
Loratadine EP Impurity A
Loratadine EP Impurity A is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: ethyl 4-[(11RS)-8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate; 11-Hydroxy Dihydro Loratadine; 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester; Loratadine USP Related Compound F; 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester; Ethyl 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylate; 11-Hydroxyloratadine; Ethyl 4-(8-chloro-11-hydroxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-carboxylate; Hydroxyloratadine. Grades: ≥95%. CAS No. 133284-74-9. Molecular formula: C22H25ClN2O3. Mole weight: 400.90.
Loxoribine
It is a small-molecule immunostimulant, toll-like receptor 7 (TLR7) agonist, TLR7 ligand and antitumor agent. Synonyms: 7,8-Dihydro-8-oxo-7-allyl-guanosine; RWJ-21757; RWJ 21757; RWJ21757; 7-Allyl-8-oxoguanosine; Loxoribina; 7-Allyl-7,8-dihydro-8-oxoguanosine; 7-Allyl-2-amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione. Grades: ≥95%. CAS No. 121288-39-9. Molecular formula: C13H17N5O6. Mole weight: 339.30.