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Kerantinocyte Growth Factor
Recombinant Human KGF is an 18.9 kDa protein containing 163 amino residues. Alternative Names: Recombinant Human KGF; rhKGF; Fibroblastgrowth factor 7; KGF; hFGF-7;HBGF-7. Grades: 95%. CAS No. 148348-15-6. Mole weight: 18.9 kDa.
Kerasin (ox brain)
Kerasin (ox brain): A protein-based extract from ox brain used in the research and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. It has shown potential for enhancing cognitive function and promoting neuronal health. Alternative Names: Tetracosanamide, N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-; N-[(1S,2R,3E)-1-[(β-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]tetracosanamide; Tetracosanamide, N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]-; Tetracosanamide, N-[1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]-, [R-[R*,S*-(E)]]-; Kerasin; C24:0 Galactosyl(β)ceramide(d18:1/24:0); D-galactosyl-β-1,1'-N-lignoceroyl-D-erythro-sphingosine; β-D-galactosyl-N-(tetracosanoyl)sphingosine; β-D-Galactosyl-N-(n-acyl)-D-sphingosine. Grades: >99%. CAS No. 74645-26-4. Molecular formula: C48H93NO8. Mole weight: 812.25.
Keratan sulfate
Keratan sulfate. CAS No. 9056-36-4.
KERATIN
KERATIN. Alternative Names: KERATIN, ANIMAL KERATIN. CAS No. 169799-44-4.
Keratin hydrolyzed
Keratin hydrolyzed is derived from wool, which must be transformed into short peptides by special biological treatment before it can be used for biological purposes. Treated keratin is recognized as a potential high-quality protein source with high nutritional value and stable quality. Keratin can be used as a repair agent and nutrient for hair. Hair contains a large amount of keratin, accounting for about 65%-95% of the hair, and many natural active proteins have a high affinity for hair, easy to absorb by hair, with nutrition and film formation. It is a hydrolysate of keratin protein derived from acid, enzyme, and other methods of hydrolysis, which has been applied in many areas including the feed and food industry, pharmacy, fertilizers, pesticides, environmental protection, leather industry, and cosmetics. Alternative Names: Keratin hydrolyzates; Keratins, hydrolyzates; Aminocol H; AS 1; AS 1 (protein); Cashmere Coat; Crotein ASK; Crotein K; Cynatine FLX; Diamin RW; Hair and hair pulp; HP (eluent); Hydrolyzed keratins; K-D; Keratec IFP PE; Keratide; Keratide TK-B; KR 30; Nutrilan Keratin W; Nutrilan Keratin WPP; Promois KR 30; Promois W-K; Promois WK-F; Promois WK-GBF; Promois WK-PD; ProSina; Protein hydrolyzates, keratin hydrolyzates; Queratan; Soluble Keratin SKSP. Grades: 90% (Protein). CAS No. 69430-36-0.
Keratins
Keratins. Alternative Names: KERATIN; KERATIN, EPIDERMAL; cheratina; detoxin; keratins; keratin from human epidermis; Keratin solution from human epidermis; Keratin, Human Epidermal. Grades: 95%. CAS No. 68238-35-7. Molecular formula: C2H2BrClO2.
Kermesic Acid
Kermesic Acid. Uses: Principle constituent of kermes, one of the oldest known insect dyes. used as brilliant scarlet dye. Alternative Names: 9,10-Dihydro-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-2-anthracenecarboxylic Acid; 1-Methyl-2-carboxy-3,5,6,8-tetrahydroxyanthraquinone; C.I. Natural Red 3; Kermes; Kermes (dye). CAS No. 18499-92-8. Molecular formula: C16H10O8. Mole weight: 330.25.
Ketanserin
Ketanserin is a specific 5-HT2A serotonin receptor antagonist with Ki of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug. Uses: Antihypertensive agents. Alternative Names: Ketanserinum; Ketaserin; 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione. CAS No. 74050-98-9. Molecular formula: C22H22FN3O3. Mole weight: 395.434.
Ketoconazole EP Impurity A
Ketoconazole EP Impurity A is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Alternative Names: 1-Acetyl-4-[4-[[(2RS,4SR)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1,2,3,4-tetrahydropyrazine; Ketoconazole Impurity A; 2,3-Dehydro Ketoconazole; rel-1-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-3,4-dihydro-1(2H)-pyrazinyl]ethanone; Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-3,4-dihydro-1(2H)-pyrazinyl]-, rel-; rel-1-(4-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-3,4-dihydropyrazin-1(2H)-yl)ethan-1-one; Pyrazine, 1-acetyl-4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1,2,3,4-tetrahydro-, rel-; R 049223. Grades: ≥95%. CAS No. 254912-63-5. Molecular formula: C26H26Cl2N4O4. Mole weight: 529.43.
Ketoconazole EP Impurity C
Ketoconazole EP Impurity C is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Alternative Names: 1-Acetyl-4-[4-[[(2RS,4RS)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine; rac-trans-Ketoconazole; Piperazine, 1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, rel-; Piperazine, 1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, trans-; rel-1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; R 44319; RS 36745; trans-Ketoconazole; Ketoconazole Impurity C. Grades: ≥95%. CAS No. 83374-59-8. Molecular formula: C26H28Cl2N4O4. Mole weight: 531.43.
Ketoconazole EP Impurity D
Ketoconazole EP Impurity D is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Alternative Names: 1-[4-[[(2RS,4SR)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, rel-; Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-, cis-; rel-1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; Deacetylketoconazole; Deacylketoconazole; N-Deacetylketoconazole; R 39519; Ketoconazole Impurity D. Grades: ≥95%. CAS No. 67914-61-8. Molecular formula: C24H26Cl2N4O3. Mole weight: 489.41.
Ketoconazole EP Impurity E (RS-Isomer)
Ketoconazole EP Impurity E (RS-Isomer) is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Alternative Names: ((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate; 1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, 4-(4-methylbenzenesulfonate), (2R,4S)-; [(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl 4-methylbenzenesulfonate. CAS No. 2095256-87-2. Molecular formula: C21H20Cl2N2O5S. Mole weight: 483.37.
Ketoconazole Impurity 1
Ketoconazole Impurity 1 is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Alternative Names: Ethanone, 1-[3,4-dihydro-4-(4-hydroxyphenyl)-1(2H)-pyrazinyl]-; 1-(4-(4-hydroxyphenyl)-3,4-dihydropyrazin-1(2H)-yl)ethan-1-one; 1-[3,4-Dihydro-4-(4-hydroxyphenyl)-1(2H)-pyrazinyl]ethanone; 1-[4-(4-Hydroxyphenyl)-3,4-dihydro-1(2H)-pyrazinyl]ethanone; Pyrazine, 1-acetyl-1,2,3,4-tetrahydro-4-(4-hydroxyphenyl)-. Grades: ≥95%. CAS No. 581806-59-9. Molecular formula: C12H14N2O2. Mole weight: 218.26.
Ketone Ester
Ketone Ester is an orally available ketone monoester with anti-obesity and anticonvulsant activities. Ketone Ester increases the seizure threshold and blood levels of β-hydroxybutyrate in a rat model of seizures induced by pentylenetetrazole. Alternative Names: BD-AcAc 2; (R,R)-BD-AcAc 2; (R)-Hydroxybutyl (R)-3-hydroxybutyrate ester; D-beta-Hydroxybutyrate ester. Grades: ≥95%. CAS No. 1208313-97-6. Molecular formula: C8H16O4. Mole weight: 176.21.
Ketoprofen EP Impurity A
Ketoprofen EP Impurity A is an impurity of Ketoprofen, which is a cyclooxygenase inhibitor used as a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. Alternative Names: Ketoprofen Related Compound D; 3-Acetylbenzophenone; 3-Benzoylacetophenone; m-Benzoylacetophenone; USP Ketoprofen Related Compound D; Ketoprofen USP Related Compound D; Ethanone, 1-(3-benzoylphenyl)-; 1-(3-Benzoylphenyl)ethan-1-one; Ketoprofen impurity A. Grades: ≥95%. CAS No. 66067-44-5. Molecular formula: C15H12O2. Mole weight: 224.26.
Ketoprofen EP Impurity C
Ketoprofen EP Impurity C is an impurity of Ketoprofen, which is a cyclooxygenase inhibitor used as a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties. Alternative Names: 3-[(1RS)-1-carboxyethyl]benzoic acid; Ketoprofen Related Compound C; 3-Carboxy-α-methylbenzeneacetic Acid; USP Ketoprofen Related Compound C; Ketoprofen USP Related Compound C; 2-(3-Carboxyphenyl)propionic Acid; 3-(1-Carboxyethyl)benzoic acid, (RS)-; Benzeneacetic acid, 3-carboxy-α-methyl-; DF 2008Y; Ketoprofen impurity C; (+/-)-3-(1-carboxyethyl)benzoic acid. Grades: ≥95%. CAS No. 68432-95-1. Molecular formula: C10H10O4. Mole weight: 194.19.
Ketorolac
Ketorolac, a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug. It shows inhibition of eicosanoid formation in HEL cells (COX-1) and LPS-stimulated Mono Mac 6 cells (COX-2), but does not significantly inhibit NO accumulation in supernatants of LPS-stimulated RAW 264.7 cells. It significantly inhibits thymidine incorporation of human osteoblasts (hOBs) upon 24 hours treatment in a dose-dependent manner, and inhibits proliferation and arrests cell cycle at G0/G1 phase in hOBs. Uses: Cyclooxygenase inhibitors. Alternative Names: Acular LS; RS37619; RS 37619; RS-37619; Sprix; Toradol. Grades: >98%. CAS No. 74103-06-3. Molecular formula: C15H13NO3. Mole weight: 255.27.
Ketorolac EP Impurity B
An impurity of Ketorolac, a medication used to treat moderate to severe acute-onset pain. Alternative Names: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one; 1-Keto Ketorolac; Ketorolac Related Compound C. Grades: > 95%. CAS No. 113502-52-6. Molecular formula: C14H11NO2. Mole weight: 225.25.
Ketorolac EP Impurity I
An impurity of Ketorolac, a medication used to treat moderate to severe acute-onset pain. Alternative Names: 1-Descarboxy Ketorolac; 2,3-Dihydro-1H-pyrrolizin-5-yl)phenylmethanone; Ketorolac Related Compound D. Grades: > 95%. CAS No. 113502-55-9. Molecular formula: C14H13NO. Mole weight: 211.27.
Ketorolac Related Compound A
An impurity of Ketorolac, a medication used to treat moderate to severe acute-onset pain. Alternative Names: rac Ketoroloc Tris Amide Impurity; (±)-5-Benzoyl-2,3-dihydro-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-1H-pyrrolizine-1-carboxamide. Grades: > 95%. CAS No. 167105-80-8. Molecular formula: C19H22N2O5. Mole weight: 358.40.
Ketorolac Related Compound B
An impurity of Ketorolac, a medication used to treat moderate to severe acute-onset pain. Alternative Names: Descarboxy 1-Hydroxy Ketorolac; (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone. Grades: > 95%. CAS No. 154476-25-2. Molecular formula: C14H13NO2. Mole weight: 227.27.
Ketorolac Tromethamine
Ketorolac Tromethamine is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. Alternative Names: 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid,compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1). CAS No. 74103-07-4. Molecular formula: C19H24N2O6. Mole weight: 376.4.
Ketotifen Impurity B
Ketotifen impurity, used in separation of enantiomers of Ketotifen and its polar intermediate by isotachophoresis. Alternative Names: 4-Hydroxy-9,10-dehydro-10-methoxy Ketotifen; 10-Methoxy-4-(1-methyl-4-piperidinyl)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene-4-ol. Grades: > 95%. CAS No. 59743-88-3. Molecular formula: C20H23NO2S. Mole weight: 341.48.
Ketotifen Impurity C
an intermediate in the synthesis of the 2-bromo derivative of Ketotifen. Alternative Names: 4-Hydroxy Ketotifen; 4,9-Dihydro-4-hydroxy-4-(1-methyl-4-piperidinyl)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one. Grades: > 95%. CAS No. 126939-27-3. Molecular formula: C19H21NO2S. Mole weight: 327.45.
Ketotifen Impurity D
A metabolite of Ketotifen. Alternative Names: Ketotifen N-Oxide; 4,9-Dihydro-4-(1-methyl-1-oxido-4-piperidinylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one; 4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo [4,5]cyclohepta[1,2-b]thiophen-10-one N-Oxide. Grades: > 95%. CAS No. 88456-70-6. Molecular formula: C19H19NO2S. Mole weight: 325.43.
Ketotifen Impurity E
Ketotifen impurity, used as antihistaminics. Alternative Names: 9-Oxo Ketotifen; 4,10-Dihydro-4-(1-methyl-4-piperidinylidene)-9H-benzo[4,5]cyclohepta[1,2-b]thiophen-9-one. Grades: > 95%. CAS No. 34580-09-1. Molecular formula: C19H19NOS. Mole weight: 309.43.
Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Alternative Names: Ki20227; Ki 20227; Ki-20227. Grades: >98%. CAS No. 623142-96-1. Molecular formula: C24H24N4O5S. Mole weight: 480.54.
Kifunensine
Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis. When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin. Alternative Names: [5R-(5α,6β,7α,8α,8aα)]-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione; (+)-Kifunensine; FR 900494; (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione; Imidazo(1,2-a)pyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R-(5alpha,6beta,7alpha,8alpha,8aalpha))-. Grades: ≥95%. CAS No. 109944-15-2. Molecular formula: C8H12N2O6. Mole weight: 232.19.
Kinase(phosphorylating), acetate
Kinase(phosphorylating), acetate. Alternative Names: EC 2.7.2.1; EC: 2.7.2.1; ATP: ACETATE PHOSPHOTRANSFERASE; ACETATE KINASE; AK; Kinase (phosphorylating), acetate; ACETATE KINASE FROM ESCHERICHIA COLI; ACETATE KINASE FROM BACILLUSSTEAROTHERMO PHILUS. Grades: 95%. CAS No. 9027-42-3.
Kinetin
Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division. Uses: Plant growth regulators. Alternative Names: 6-Furfuryladenine; Kinetin; NSC 23119; NSC-23119; NSC23119. Grades: >98%. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21.
Kinetin Riboside
Kinetin Riboside is a cell growth inhibitor used as an anticancer and antiviral agent. Kinetin Riboside is a modified nucleoside where a furfuryl group is attached to the sixth position nitrogen of the adenosine base. This modification is utilized in biochemical research to investigate nucleic acid structure and function, RNA modification studies, and drug development due to its potential to modulate nucleic acid metabolism. Its altered chemical properties make it a valuable tool for understanding RNA biology and exploring therapeutic applications. Alternative Names: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine. Grades: 98%. CAS No. 4338-47-0. Molecular formula: C15H17N5O5. Mole weight: 347.33.
Kino, eucalyptus
Kino, eucalyptus. Alternative Names: ACCROIDES GUM; GUM ACCROIDES; GUM YACCA; YACCA; RED GUM; Kino, eucalyptus; Red gum, Yacca. Grades: 95%. CAS No. 9000-20-8. Molecular formula: CAS: 9000-20-8.
KL-11743
KL-11743 is a potent, orally active and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90 and 68 nM for GLUT1, GLUT2, GLUT3 and GLUT4, respectively. It specifically blocks glucose metabolism and induces cell death in concert with electron transport inhibitors. Alternative Names: NSC783733; Acetamide, 2-[3-[6-ethoxy-4-[[4-(1H-pyrazol-4-yl)phenyl]amino]-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-. Grades: ≥98%. CAS No. 1369452-53-8. Molecular formula: C30H30N6O3. Mole weight: 522.60.
Kojic Acid Dipalmitate
Kojic Acid Dipalmitate is a fat-soluble derivative of kojic acid. Due to the special function of the hydroxyl group in its molecular structure, it will not affect the performance of other cosmetic additives and can be well compounded with other cosmetic raw materials. Alternative Names: KAD. Grades: 98%. CAS No. 79725-98-7. Molecular formula: C37H64O6. Mole weight: 604.9.
Kojitriose
Kojitriose is an intricate trisaccharide compound, extensively employed within the biomedical sphere due to its underlying propensities for studying obesity, metabolic disorders and concomitant cardiovascular complications. CAS No. 74738-47-9. Molecular formula: C18H32O16. Mole weight: 504.44.
Konjac glucomannan
Konjac glucomannan is an acetylated (1-4)-β-D-glucomannan extracted from the tubers of Amorphophallus konjac or Konnyaku root. In Japan, it is a dietary supplement designed to reduce calorie intake because it expands in water. Alternative Names: Konjac powder; Konjac flour; Konjak mannan; GM-B (mannan); GM-C (polysaccharide); Gums, konjak; H 18; H 18 (polysaccharide); Hemannan; Inagel Fine Mannan; Inagel Mannan 100; Inagel Mannan 180; Inagel Mannan S; Konjac; Konjac glucomannan; Konjac gum; Konjac K; Konjac mannan; Konjak; Konjak gum; Konnyaku; Luxara 208-1; Mannan 100; Mannan, konjak; Nutricol; Propol; Propol A; Rheolex One; Rheolex RS; Rheolex RS-H; Ticagel; Ticagel Konjac HV; Timac Mannan. CAS No. 37220-17-0.
Kopexil
Kopexil is a new type of anti-hair shedding active substance, which can act on the deep structure of the hair root during the growth stage of hair to increase the number of hair, restore the vitality of the hair root, and make the hair grow continuously and healthily. As a potassium channel developer, it enables hair follicles to shift from the resting phase to the growth phase, prolongs the growth phase of hair, dilates peripheral capillaries, promotes the nutrients required for hair growth, and promotes the proliferation of dermal papilla cells. Alternative Names: 2,4-Pyrimidinediamine, 3-oxide; 2,4-Diaminopyrimidine 3-N-oxide; 2,6-Diaminopyrimidin-1-ium-1-olate; 2,4-Diaminopyrimidine 3-oxide; Diaminopyrimidine Oxide. Grades: >95%. CAS No. 74638-76-9. Molecular formula: C4H6N4O. Mole weight: 126.12.
KRAS G12C inhibitor 19
KRAS G12C inhibitor 19 is a potent inhibitor of KRAS G12C extracted from patent WO2021118877A1. KRAS G12C inhibitor 19 significantly inhibits tumor growth. CAS No. 2649788-46-3. Molecular formula: C25H19ClF2N4O3S. Mole weight: 528.96.
KRN5500
KRN5500 is a semisynthetic derivative of the nucleoside-like antineoplastic antibiotic spicamycin, originally isolated from the bacterium Streptomyces alanosinicus. KRN 5500 inhibits protein synthesis by interfering with endoplasmic reticulum and Golgi apparatus functions. This agent also induces cell differentiation and caspase-dependent apoptosis. Alternative Names: KRN-5500; KRN 5500; SPK-241; SPK241; SPK 241; NSC-650426; 4-Deoxy-N-(7H-purin-6-yl)-4-(((2,4-tetradecadienoylamino)acetyl)amino)heptopyranosylamine. CAS No. 151276-95-8. Molecular formula: C28H43N7O7. Mole weight: 589.69.
KRN7000
KRN7000 is a synthetic analog of α-galactosylceramide and the marine natural product agelasphin. It is a specific ligand for human and mouse NKT cells and remains the best studied ligand of the lipid-binding MHC class I-like protein CD1d. It protects against LPS-induced shock and displays potent antitumor activity in various in vivo models. Alternative Names: a-Gal-Cer; N-[(1S,2S,3R)-1-[(a-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide. Grades: ≥95%. CAS No. 158021-47-7. Molecular formula: C50H99NO9. Mole weight: 858.32.
KRYPTOFIX(R) 211
Applications: 4,7,13,18-Tetraoxa-1,10-diazabicyclo[8.5.5]eicosane is a useful research chemical. Alternative Names: 4,7,13,18-TETRAOXA-1,10-DIAZABICYCLO[8.5.5]EICOSANE; KRYPTOFIX 211; KRYPTOFIX(R) 211; 4,7,13,18-tetraoxa-1,10-diazabicyclo[8.5.5]icosane; KRYPTOFIX 211 95+%; cryptating agent 211; [2.1.1]Cryptand; 4,10-(Ethylenebisoxybisethylene)-1,7-dioxa-4,10-diazacyclododeca. CAS No. 31250-06-3. Molecular formula: C14H28N2O4. Mole weight: 288.38.
KU-0063794 is an inhibitor of both mTORC1 and mTORC2 with an IC50 of approximately 10 nM, but does not suppress the activity of 76 other protein kinases or seven lipid kinases, including Class 1 PI3Ks (phosphoinositide 3-kinases) at 1000-fold higher concentrations. KU-0063794 is cell permeant, suppresses activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK (ribosomal S6 kinase), an AGC kinase not regulated by mTOR. It also inhibited phosphorylation of the T-loop Thr308 residue of Akt phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase-1). It does not affect Thr308 phosphorylation in fibroblasts lacking essential mTORC2 subunits. KU-0063794 also suppressed cell growth and induced a G1-cell-cycle arrest. KU-0063794 will be useful in delineating the physiological roles of mTOR and may have utility in treatment of cancers in which this pathway is inappropriately activated. Uses: Differentiation. Alternative Names: KU0063794; KU-0063794; KU 0063794; Ku0063794; Ku 0063794; Ku-0063794; KU63794; KU 63794; KU-63794; [5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol. Grades: 0.98. CAS No. 938440-64-3. Molecular formula: C25H31N5O4. Mole weight: 465.554.
Kulactone
Kulactone is a potent synthetic natural compound extensively used in the biomedical industry. With its exceptional anti-inflammatory properties, Kulactone is primarily employed in the research of chronic auto-inflammatory disorders, such as rheumatoid arthritis, psoriasis and Crohn's disease. Alternative Names: KULACTONE; 22611-36-5; 16,21-epoxylanosta-7,24-diene-3,21-dione; EPIKULACTONEDTXSID40945269. Grades: >98%. CAS No. 22611-36-5. Molecular formula: C30H44O3. Mole weight: 452.7.
Kuromanin chloride
Kuromanin chloride is a natural compound found in Amelanchier spicata, Acer paxii. It is a scavenger of peroxynitrite that exerts a protective effect against endothelial dysfunction and vascular failure induced by peroxynitrite. Uses: Antioxidative. Alternative Names: Kuromanine; Chrysontemin; Cyanidin-3-glucoside chloride. Grades: >98%. CAS No. 7084-24-4. Molecular formula: C21H21O11Cl. Mole weight: 484.85.
Kynurenic acid
Kynurenic acid is a product of L-Tryptophan metabolism. It is a non-selective antagonist at NMDA and AMPA / kainate receptors. It could block kainic acid neurotoxicity. It has neruoactive activity having anticonvulsant and antiexcitotoxic properties. Uses: Excitatory amino acid antagonists. Alternative Names: 4-Hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-quinaldic Acid; 2-Carboxy-4-hydroxyquinoline; 4-Hydroxyquinaldic Acid; Quinurenic Acid; NSC 58973; 4-Hydroxyquinoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 492-27-3. Molecular formula: C10H7NO3. Mole weight: 189.17.
Kytamer L
Kytamer L. CAS No. 66267-50-3.
L 012 sodium salt
L 012 sodium salt is a luminal-based chemiluminescent dye and probe. It is used to detect superoxide in biological systems, specifically in whole inflammatory cells, vascular tissue and blood. It could detect NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). It is active in vitro and in vivo. Alternative Names: 8-Amino-5-chloro-2,3-dihydro-7-phenyl-pyrido[3,4-d]pyridazine sodium salt. Grades: ≥98% by HPLC. CAS No. 143556-24-5. Molecular formula: C13H8CIN4NaO2. Mole weight: 310.67.
L-2-Hydroxyglutaric acid disodium salt
L-2-Hydroxyglutaric acid disodium salt. Uses: A potential inhibitor of glutamate carboxypeptidase. Alternative Names: (2S)-2-Hydroxypentanedioic Acid; L-2-Hydroxyglutaric Acid Disodium Salt; (S)-α-Hydroxyglutaric Acid Disodium Salt; L-2-Hydroxyglutarate Disodium Salt. Grades: 95%. CAS No. 63512-50-5. Molecular formula: C5H8Na2O5. Mole weight: 192.08.
L-858,051 hydrochloride
L-858,051 is a water-soluble analog of forskolin that acts as an adenylate cyclase activator. It inhibited the 5-HT-stimulated inositol phosphate (IP) accumulation in canine cultured aorta smooth muscle cells (ASMCs). Alternative Names: [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] 4-(4-methylpiperazin-1-yl)butanoate dihydrochloride. Grades: ≥95%. CAS No. 115116-37-5. Molecular formula: C29H50N2O8·2HCl. Mole weight: 609.6.
Labdanum
Labdanum. Grades: 95%. CAS No. 84775-64-4.
Labetalol Impurity C
an intermediate of Labetalol Impurity. Alternative Names: 5-(N,N-Dibenzylglycyl)salicylamide. Grades: > 95%. CAS No. 30566-92-8. Molecular formula: C23H22N2O3. Mole weight: 374.44.
Labetuzumab
Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with antineoplastic activity. Labetuzumab has been used as an adjuvant treatment for colorectal cancer. Alternative Names: CEA-CIDE. CAS No. 219649-07-7.
LACCASE
LACCASE. Alternative Names: EC 1.10.3.2; LACC; LACCASE; LACCASE AB; LACCASE, CORIOLUS VERSICOLOR, CLEA; LACCASE, CORIOLUS VERSICOLOR, CROSS-LINKED ENZYME AGGREGATE; LACCASE CV; LACCASE T. Grades: 95%. CAS No. 80498-15-3.
Laccol
Laccol (CAS# 5862-27-1 ) is a useful research chemical. Alternative Names: 3-Heptadecylcatechol; Heptadecylcatechol. CAS No. 5862-27-1. Molecular formula: C23H40O2. Mole weight: 348.57.
Lactalbumin from bovine milk
Lactalbumin from bovine milk. CAS No. 9051-29-0. Molecular formula: CH4V28. Mole weight: 1442.40.
Lactate Oxidase from Pediococcus sp.
Lactate Oxidase from Pediococcus sp. CAS No. 9028-72-2.
Lactisole is a sweet taste receptor antagonist that suppresses perception of sweetness in humans. It blocks a heterodimeric receptor comprised of T1R2+T1R3, which detects sweet-tasting compounds. Alternative Names: na-PMP; Sodium 2-(4-methoxyphenoxy)propanoate. Grades: ≥98%. CAS No. 150436-68-3. Molecular formula: C10H11O4·Na. Mole weight: 218.18.
Lactitol EP Impurity B
an impurity of Lactitol. Lactitol is listed as an excipient in some prescription drugs, such as Adderall. Alternative Names: Lactitol Impurity B; D-Mannitol, 3-O-β-D-galactopyranosyl-; 3-O-β-D-Galactopyranosyl-D-mannitol; Mannitol, 3-O-β-D-galactopyranosyl-, D-; Lactulitol. Grades: >95%. CAS No. 53796-37-5. Molecular formula: C12H24O11. Mole weight: 344.32.
Lactitol monohydrate
Lactitol monohydrate is an analogue of disaccharide lactulose. lt is used as a replacement sweetener and has been used in the treatment of constipation & hepatic encephalopathy. Alternative Names: 4-O-(b-D-Galactopyranosyl)-D-glucitol monohydrate; 4-O-β-D-Galactopyranosyl-D-glucitol Monohydrate; Exportal. Grades: >98%. CAS No. 81025-04-9. Molecular formula: C12H24O11.H2O. Mole weight: 362.33.
Lactobacillus acidophilus
Lactobacillus acidophilus. Alternative Names: Bacillus acidophilus; Bacterium acidophilum; FD-DVS YF 3331; Fruitsan; Lacteol; Lactobacterium acidophilum. CAS No. 68333-16-4.
Lactodifucotetraose
Lactodifucotetraose is a notable bioactive compound, emerging as a promising compound in studying ailments concerning the gastrointestinal realm. Its innate potential lies in fostering the proliferation of symbiotic gut microflora and catalyzing the intricate process of digestive assimilation. By virtue of its robust prebiotic attributes, Lactodifucotetraose efficaciously propels the state of gut well-being through studying inflammatory responses and fortifying the resilience of the immune system. Alternative Names: LDFT; Difucosyl lactose; O-6-Deoxy-α-L-galactopyranosyl-(1→3)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-β-D-galactopyranosyl-(1→4)]-D-glucose; 2',3-Difucosyllactose; Difucosyllactose; Lacto-difucosyl-tetraose; Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]aldehydo-Glc. Grades: 95%. CAS No. 20768-11-0. Molecular formula: C24H42O19. Mole weight: 634.58.
Lactofen
Lactofen is a selective post-budding herbicide, which can effectively control broad-leaved weeds in soybean, cotton, peanut, rice, corn, grape, and other crops. Alternative Names: Benzoic acid, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitro-, 2-ethoxy-1-methyl-2-oxoethyl ester; 2-Ethoxy-1-methyl-2-oxoethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate; Cobra; Cobra (herbicide); Phoenix; Phoenix (herbicide); PPG 844; 5-(2-Chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoic acid 2-ethoxy-1-methyl-2-oxoethyl ester. Grades: 95%. CAS No. 77501-63-4. Molecular formula: C19H15ClF3NO7. Mole weight: 461.78.
Lacto-N-biose
It is the receptor of helicobacter pylori α1,2-Focusyltransferase enzyme. Alternative Names: Galβ1-3GlcNAc; Gal-b-1,3-GlcNAc; 2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-D-glucopyranose; beta-D-galactsyl-(1->3)-N-acetyl-D-glucosamine; beta-D-Galactopyranosyl-(1->3)-N-acetyl-D-glucosamine; O-β-D-Galactopyranosyl-(1-3)-N-acetylglucosamine; Lewis C. Grades: ≥95%. CAS No. 50787-09-2. Molecular formula: C14H25NO11. Mole weight: 383.35.
Lacto-N-difucohexaose I
Lacto-N-difucohexaose I is an indispensable compound in the biomedical field, exhibiting remarkable immunomodulatory attributes. Its application predominantly encompasses the research of multifarious ailments, encompassing particular cancer types and autoimmune afflictions. As a propitious research, this product adeptly modulates the immune response, potentially augmenting patient outcomes with unprecedented efficacy. Alternative Names: LNDFH I; Lewisb antigen; 6-Deoxy-α-L-galactopyranosyl-(1->4)-[6-deoxy-α-L-galactopyranosyl-(1->2)-β-D-galactopyranosyl-(1->3)]-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->3)-β-D-galactopyranosyl-(1->4)-D-glucose; α-L-Fuc-(1-2)-β-D-Gal-(1-3)[α-L-Fuc-(1-4)]-β-D-GlcNAc-(1-3)-β-D-Gal-(1-4)-D-Glc; O-6-Deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-[6-deoxy-α-L-galactopyranosyl-(1→4)]-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucose; Lacto-N-difucohexaose; LND 1; LND I; LNDFH-I. Grades: ≥95%. CAS No. 16789-38-1. Molecular formula: C38H65NO29. Mole weight: 999.91.
LACTONE OF CIS JASMONE
Cis Jasmone Lactone, a promising antitumor compound, demonstrates cytotoxicity against a range of cancer cell types, notably colon and breast cancer. Furthermore, its anti-inflammatory characteristics suggest potential applications in managing conditions like arthritis. Alternative Names: (Z)-5-Hex-3-enyldihydro-5-methylfuran-2(3H)-one, 2(3H)-Furanone, 5-(3-hexenyl)dihydro-5-methyl-, (Z)-, 2(3H)-Furanone, 5-(3Z)-3-hexenyldihydro-5-methyl-, 4-Methyl-4-hydroxy-cis-7-decenoic acid lactone, LACTONE OF CIS JASMONE. Grades: 97.0% (sum of isomers). CAS No. 70851-61-5. Molecular formula: C11H18O2. Mole weight: 182.26.
Lacto-N-fucopentaose I
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and Apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development. Alternative Names: LNFP I; Fuc-a-1,2-Gal-b-1,3-GlcNAc-b-1,3-Gal-b-1,4-Glc; Blood group O(H) type I determinant; α-l-fuc(1→2)-β-d-gal-(1→3)-β-d-glcnac-(1→3)-β-d-gal-(1→4)-d-glc; O-6-Deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucose; Lacto-N-fucopentose 1; Lacto-N-fucopentose I; LNF 1; LNF I. Grades: ≥95%. CAS No. 7578-25-8. Molecular formula: C32H55NO25. Mole weight: 853.77.
Lacto-N-fucopentaose III
It is a human milk oilgosaccharide that can inhibit the adherence of pathogens to the intestinal epithelium. Alternative Names: LNFP III; Lewis X antigen; Gal-b-1,4-(Fuc-a-1,3)-GlcNAc-b-1,3-D-Gal-b-1,4-Glc; Lex-lactosel; Lewis-X pentasaccharide; β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→4)-D-Glcp; O-6-deoxy-alpha-L-galactopyranosyl-(1->3)-O-[beta-D-galactopyranosyl-(1->4)]-O-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-O-beta-D-galactopyranosyl-(1->4)-D-Glucopyranose; 6-Deoxy-α-L-galactopyranosyl-(1->3)-[β-D-galactopyranosyl-(1->4)]-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->3)-β-D-galactopyranosyl-(1->4)-D-glucose; Lacto-N-neofucopentaose II. Grades: ≥95%. CAS No. 25541-09-7. Molecular formula: C32H55NO25. Mole weight: 853.77.