BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| [Ala17]-MCH acetate | [Ala17]-MCH is a melanin-concentrating hormone receptor agonist with EC50 values of 17 and 54 nM at MCH1 and MCH2 receptors. Molecular formula: C99H159N29O28S4. Mole weight: 2331.76. |  |
| (Ala1)-PAR4 (1-6) amide (mouse) trifluoroacetate salt | (Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively). Synonyms: AY-NH2; AYPGKF-NH2; H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2; PAR4-AP; Proteinase-Activated Receptor 4 Activating Peptide; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide trifluoroacetate salt. Grade: ≥95%. Molecular formula: C34H48N8O7·xCF3COOH. Mole weight: 680.79. | |
| (Ala1)-PAR4 (1-6) (mouse) trifluoroacetate salt | (Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60. Synonyms: H-Ala-Tyr-Pro-Gly-Lys-Phe-OH; L-alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalanine trifluoroacetate salt. Grade: ≥95%. Molecular formula: C34H47N7O8·xCF3COOH. Mole weight: 681.78. | |
| (αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide | (αR)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide, commonly referred to as TGBO, is an indispensible compound widely utilized in the realm of biomedical research. Its significance lies in its pivotal role as a tool for investigating the treatment of diverse diseases and facilitating drug development. Uses: (r)-prunasin intermediate. CAS No. 207512-68-3. Molecular formula: C22H27NO11. Mole weight: 481.45. | |
| (αR,βR)-rel-6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol | One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: Voriconazole (2R,3R)-Isomer; Voriconazole 3-Epimer; (2R,3R)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol compound with (2S,3S); Voriconazole Impurity 12. CAS No. 137234-76-5. Molecular formula: C16H13ClF3N5O. Mole weight: 383.76. | |
| (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester | (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester is used in the synthesis of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Uses: Used in the synthesis of paclitaxel metabolite. Synonyms: tert-butyl ((1S,2R)-1-(4-(benzyloxy)phenyl)-2-hydroxy-3-oxohexyl)carbamate; Paclitaxel Impurity 100; Ethyl (2R,3S)-3-[4-(benzyloxy)phenyl]-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-4-(phenylmethoxy)-, ethyl ester, (αR,βS)-. Grade: ≥95%. CAS No. 382596-26-1. Molecular formula: C23H29NO6. Mole weight: 415.48. | |
| (αR,βS)-β-(Acetylamino)-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester | (αR,βS)-β-(Acetylamino)-α-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Uses: Used in the synthesis of paclitaxel metabolite. Synonyms: (alphaR,betaS)-beta-(Acetylamino)-alpha-hydroxy-4-(phenylmethoxy)-benzenepropanoic Acid Ethyl Ester. Grade: > 98%. CAS No. 382596-25-0. Molecular formula: C20H23NO5. Mole weight: 357.40. | |
| (αS)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide | (αS)-α-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)oxy]benzeneacetamide, a compound widely utilized in the biomedical sector, plays a pivotal role in the therapeutic approach for a diverse range of ailments by acting as an efficacious inhibitor or catalyst. Synonyms: Benzeneacetamide, α-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-, (αS)-. CAS No. 1840963-44-1. Molecular formula: C22H27NO11. Mole weight: 481.45. | |
| (alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester hydrochloride | An intermediate of Carfilzomib, which is a second-generation proteasome inhibitor for the treatment of relapsed and refractory multiple myeloma. Synonyms: L-Phenylalanine, (αS)-α-aminobenzenebutanoyl-L-leucyl-, methyl ester, hydrochloride (1:1); H-hPhe-Leu-Phe-OMe.HCl; L-homophenylalanyl-L-leucyl-L-phenylalanine methyl ester hydrochloride; Methyl ((S)-2-amino-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate hydrochloride; Carfilzomib KSM; Carfilzomib main chain; Methyl (αS)-α-aminobenzenebutanoyl-L-leucyl-L-phenylalanine hydrochloride. Grade: ≥95%. CAS No. 1960444-13-6. Molecular formula: C26H35N3O4.HCl. Mole weight: 490.04. | |
| (αS)-N-[(1R,4R)-4-Amino-5-phenyl-1-(phenylmethyl)pentyl]-α-[[[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]-4-morpholinebutanamide | An impurity of Cobicistat, a cytochrome P450 3A (CYP3A) inhibitor used for the treatment of HIV/AIDS infection. Grade: 90%. CAS No. 1992785-25-7. Molecular formula: C35H50N6O3S. Mole weight: 634.88. | |
| (αZ)-2-Amino-α-[(1-carboxy-1-methylethoxy)imino]-4-thiazoleacetic Acid | (αZ)-2-Amino-α-[(1-carboxy-1-methylethoxy)imino]-4-thiazoleacetic Acid can be used in the synthesis of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Synonyms: Aztreonam impurity 15. Grade: 95%. CAS No. 102507-85-7. Molecular formula: C9H11N3O5S. Mole weight: 273.26. | |
| [Arg14,Lys15]Nociceptin | [Arg14,Lys15]Nociceptin behaves as a highly potent agonist of the OP(4) receptor (EC50 = 1 nM) and is able to produce long-lasting effects in vivo, compared with the natural ligand NC. It exhibits > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Synonyms: H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Arg-Lys-Asn-Gln-OH; [Arg(14),Lys(15)]NC. CAS No. 236098-40-1. Molecular formula: C82H137N31O22. Mole weight: 1909.18. | |
| [Arg14,Lys15]Nociceptin TFA | [Arg14,Lys15]Nociceptin is a highly potent and selective NOP receptor (ORL1; OP4) agonist with an EC50 of 1 nM. It displays high selectivity over opioid receptors, with IC50s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively. Molecular formula: C84H138F3N31O24. Mole weight: 2023.18. | |
| [Asp5,Gly9-OH]-Atosiban | An impurity of Atosiban. Atosiban is a synthetic peptide that acts as a selective oxytocin receptor antagonist, primarily used to delay preterm labor in pregnant women. Synonyms: Mpr-DTyr(Et)-Ile-Thr-Asp-Cys-Pro-Orn-Gly(Mpr1&Cys6 bridge); deamino-Cys-D-Tyr(Et)-Ile-Thr-Asp-Cys-Pro-Orn-Gly (Disulfide bridge: Cys1-Cys6); Deamino-cysteinyl-O4-ethyl-D-tyrosyl-L-isoleucyl-L-threonyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-ornithyl-glycine (1->6)-disulfide; [Asp5,Gly9]-Atosiban; Asp5,Gly9-Atosiban; Asp5 Gly9 Atosiban; Asp5,Gly9-OH-Atosiban. Grade: ≥95%. CAS No. 2014351-17-6. Molecular formula: C43H65N9O14S2. Mole weight: 996.16. | |
| [Asp5]-Oxytocin acetate | [Asp5]-Oxytocin acetate is the first 5-position neurohypophyseal hormone analog possessing significant biological activity. [Asp5]-Oxytocin acetate can induce uterine contractions in rats in vitro and can be enhanced by Mg2+. Synonyms: Cys-Tyr-Ile-Gln-Asp-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6). Molecular formula: C45H69N11O15S2. Mole weight: 1068.22. | |
| (β)-1-D-Ribofuranosyl-3-guanylurea | (α)-1-D-Ribofuranosyl-3-guanylurea is a labile hydrolysis product of the antitumor nuceloside 5-Azacytidine. Synonyms: N-(Aminoiminomethyl)-N'-β-D-ribofuranosylurea; 1-β-D-Ribofuranosyl-3-guanylurea; NSC 264412; 1-(Diaminomethylidene)-3-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea; 3-Carbamimidoyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]urea. Grade: 96 %. CAS No. 2508-80-7. Molecular formula: C7H14N4O5. Mole weight: 234.21. | |
| [betaAla-D-Cit]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-beta-Ala-DCit-Leu-Arg-Pro-DAla-NH2; [β-Ala-D-Cit]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-β-Ala-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-beta-alanyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-DCit-Cetrorelix; betaAla-D-Cit-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14. | |
| [betaAla-Leu]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-beta-Ala-Leu-Arg-Pro-DAla-NH2; [β-Ala-Leu]-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-β-Ala-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-beta-alanyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; betaAla-Leu-Cetrorelix. Grade: ≥95%. Molecular formula: C73H97ClN18O15. Mole weight: 1502.14. | |
| (beta)-Estradiol 17-acetate | β-Estradiol 17-acetate is a metabolite of estradiol. Synonyms: 1,3,5(10)-Estratriene-3,17β-diol 17-acetate. Grade: >98%. CAS No. 1743-60-8. Molecular formula: C20H26O3. Mole weight: 314.42. | |
| (βS,δS)-Atorvastatin tert-Butyl Ester | (βS,δS)-Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: (3S,5S)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate; 2-Methyl-2-propanyl (3S,5S)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate; (βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester. CAS No. 1428118-12-0. Molecular formula: C37H43FN2O5. Mole weight: 614.75. | |
| (Chloromethyl)cyclohexane | (Chloromethyl)cyclohexane is a common chemical reagent used in the synthesis of imidazole inhibitors of cytokine release which suppresses the response to tumor necrosis factor. Synonyms: 1-Chloromethylcyclohexane; Cyclohexylmethyl chloride; Cyclohexane, (chloromethyl)-. Grade: >95%. CAS No. 1072-95-3. Molecular formula: C7H13Cl. Mole weight: 132.63. | |
| (cis)-phenyl 3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate | An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Synonyms: Paroxetine Impurity 24. Grade: >95%. CAS No. 105812-85-9. Molecular formula: C26H24FNO5. Mole weight: 449.48. | |
| [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide | A Y5 receptor-selective agonist (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1-0.15 nM). Synonyms: GPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY. CAS No. 313988-89-5. Molecular formula: C183H281N57O54S2. Mole weight: 4207.67. | |
| (Cys(S)²)-Octreotide trifluoroacetate salt | Trisulfide Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: H-D-Phe-Cys(S)-Phe-D-Trp-Lys-Thr-Cys-L-threoninol trifluoroacetate salt (Trisulfide bond); Trisulfide Octreotide trifluoroacetate salt. Grade: 95%. | |
| [d5]-Ethyl b-D-glucuronide | [d5]-Ethyl b-D-glucuronide is a paramount and unparalleled biochemical compound, diligently employed within the biomedical industry as a powerful tool to delve into the intricate realm of drug metabolism and pharmacokinetics. This intriguing compound assumes the role of a remarkably stable isotope-labeled internal standard, flawlessly navigating the labyrinthine glucuronidation pathways. Synonyms: d5-Ethyl-b-D-6-glucuronide; d5-Ethyl b-D-glucuronide. Molecular formula: C8H9D5O7. Mole weight: 227.22. | |
| (D-Ala2,D-Leu5)-Enkephalin Trifluoroacetate | (D-Ala2,D-Leu5)-Enkephalin is a prototypical δ-opioid receptor agonist with antinociceptive activity. It also exhibits activity at the μ-opioid receptor. Synonyms: L-tyrosyl-D-alanyl-glycyl-L-phenylalanyl-D-leucine trifluoroacetic acid; (D-Ala2,D-Leu5)-Enkephalin TFA salt; DADLE TFA salt. Molecular formula: C31H40F3N5O9. Mole weight: 683.67. | |
| [D-ala2]-Liraglutide | [D-ala2]-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: D-ala2-Liraglutide; H-His-D-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(1)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.palmitoyl-Glu(1)-OH. Molecular formula: C172H265N43O51. Mole weight: 3751. | |
| (Dap22)-ShK | (Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK-Dap22 is an extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Synonyms: (DAP22)-SHK; ShK-Dap22. Grade: > 97%. CAS No. 220384-25-8. Molecular formula: C166H268N54O48S7. Mole weight: 4012.8. | |
| [D-Arg30]-Semaglutide | [D-Arg30]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6R,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| [D-Arg8]-Cetrorelix | [D-Arg8]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-DArg-Pro-DAla-NH2; D-Arg8-Cetrorelix; (D-Arg8)-Cetrorelix; D-Arg(8)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-D-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-D-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-78-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| [D-Cit(Ac)6]Cetrorelix | [D-Cit(Ac)6]Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit(Ac)-Leu-Arg-Pro-DAla-NH2; DCit(Ac)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit(Ac)-Leu-Arg-Pro-D-Ala-NH2; D-Cit(Ac)6-Cetrorelix; D-Cit(Ac)-Cetrorelix; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N-acetyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-[(acetylamino)carbonyl]-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 1631741-33-7. Molecular formula: C72H94ClN17O15. Mole weight: 1473.07. | |
| [D-Cys]-Lanreotide | [D-Cys]-Lanreotide is an impurity of Lanreotide, which is a somatostatin analogue with antineoplastic activity. Synonyms: D2Nal-Cys-Tyr-DTrp-Lys-Val-DCys-Thr-NH2(Cys2&Cys7 bridge); H-DPhe-cyclo[DPen-Tyr-DTrp-Lys-Val-Cys]-Thr-NH2; 3-(2-Naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-D-cysteinyl-L-threoninamide (2->7)-disulfide; D2Nal-CY-DTrp-KV-DCys-T-NH2(Cys2&Cys7 bridge); H-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-D-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); D-Cys7-Lanreotide; [D-Cys7]-Lanreotide; D-Cys(7)-Lanreotide; Lanreotide Impurity A; D-Cys-7 Lanreotide; BIM-23255; L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-D-cysteinyl-, cyclic (2→7)-disulfide; H-D-2Nal-Cys-Tyr-D-Trp-Lys-Val-D-Cys-Thr-NH2 (Disulfide bridge between cysteines); Lanreotide impurity 17. Grade: ≥95%. CAS No. 205234-53-3. Molecular formula: C54H69N11O10S2. Mole weight: 1096.33. | |
| [Des-Ac-D-2Nal]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; Des-Ac-D2NalCetrorelix; D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; 4-Chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; Des-Ac-D2Nal-Cetrorelix; [Des-Ac-D-2Nal]1-Cetrorelix. Grade: ≥95%. Molecular formula: C55H79ClN16O12. Mole weight: 1191.79. | |
| [Des-D-Ala-NH2]-Cetrorelix | An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-Pro; Des-DAla-NH2-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-OH; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-proline; [Des-D-Ala-NH2]10-Cetrorelix; Des-D-Ala-Cetrorelix; 1-9 Acid Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Proline. Grade: ≥95%. CAS No. 2901757-75-1. Molecular formula: C67H86ClN15O14. Mole weight: 1360.97. | |
| [Des-Gly9-NH2]-Atosiban | An impurity of Atosiban. Atosiban is a synthetic peptide that acts as a selective oxytocin receptor antagonist, primarily used to delay preterm labor in pregnant women. Synonyms: Mpr-DTyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn(Mpr1&Cys6 bridge); deamino-Cys-D-Tyr(Et)-Ile-Thr-Asn-Cys-Pro-Orn-OH (Disulfide bridge: Cys1-Cys6); Deamino-cysteinyl-O4-ethyl-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparagyl-L-cysteinyl-L-prolyl-L-ornithine (1->6)-disulfide; Atosiban impurity C; Des-(Gly9-NH2)-Atosiban; Des-Gly9-NH2-Atosiban; L-Ornithine, O-ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-, cyclic (1→5)-disulfide. Grade: ≥95%. CAS No. 168102-71-4. Molecular formula: C41H63N9O12S2. Mole weight: 938.12. | |
| [Des-His1,Glu9]-Glucagon (1-29) amide trifluoroacetate salt | [Des-His1,Glu9]-Glucagon (1-29) amide is a peptide glucagon receptor antagonist (pA2 = 7.25 for glucagon binding to isolated rat liver membranes). It binds to glucagon receptors in a magnesium- and GTP-independent manner to stimulate breakdown of inositol phospholipids by phospholipase C, but has no effect on adenylate cyclase activity, in hepatocytes. In vivo, [Des-His1,Glu9]-glucagon (1-29) amide prevents glucagon-induced hyperglycemia in rabbits and decreases blood glucose in rats with diabetes induced by streptozotocin. Grade: ≥95%. Molecular formula: C148H221N41O47S·xCF3COOH. Mole weight: 3358.65. | |
| [des-Thr-ol8]-D-Cys7-octreotide | [des-Thr-ol8]-D-Cys7-octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: H-D-Phe-Cys(1)-Phe-D-Trp-Lys-Thr-D-Cys(1)-ol; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-ol (Disulfide bridge: Cys2-Cys7). Molecular formula: C45H57N9O9S2. Mole weight: 932.13. | |
| [Des-Thr-ol]8-Des-D-Trp4-Octreotide | An impurity of Octreotide. Octreotide is a synthetic long-acting cyclic octapeptide that inhibits growth hormone, glucagon and insulin more effectively than somatostatin. Synonyms: DPhe-Cys-Phe-Lys-Thr-Cys(Cys2&Cys6 bridge); DPhe-CF-KTC(Cys2&Cys6 bridge); [Des-Thr-ol]8-[Des-D-Trp]4-Octreotide; [Des-Thr-ol8]-[Des-D-Trp4]-Octreotide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-L-lysyl-L-threonyl-L-cystine (2->6)-disulfide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-L-lysyl-L-threonyl-L-cystine (Disulfide Bridge between Cys2-Cys6); H-D-Phe-Cys-Phe-Lys-Thr-Cys-OH (Disulfide bridge: Cys2-Cys6). Grade: ≥95%. Molecular formula: C34H47N7O8S2. Mole weight: 745.91. | |
| [D-Glu3]-Semaglutide | [D-Glu3]-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (3R,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,45S,48S,51S,54S,81R)-54-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-45-(3-amino-3-oxopropyl)-12-benzyl-39-(2-carboxyethyl)-21-(carboxymethyl)-33-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,27,30-tris(hydroxymethyl)-36-isobutyl-24-isopropyl-48,51-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,60,69,78,83-henicosaoxo-62,65,71,74-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,59,68,77,82-henicosaazanonanonacontane-1,81,99-tricarboxylic acid. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| (D-Glycero-a-D-manno-heptopyranosyl)-dihydrogenphosphate cyclohexylammonium salt | (D-Glycero-a-D-manno-heptopyranosyl)-dihydrogenphosphate cyclohexylammonium salt, a notable compound within the biomedical sector for its extensive utilization in research based studies, can be employed in examining aspects related to the biosynthesis of heptose-containing antibiotics, for example, tunicamycin. Molecular formula: C7H15O10P.C6H13N. Mole weight: 389.34. | |
| (D-Glycero-α-D-manno-heptopyranosyl)-dihydogenphosphate, Cyclohexylammonium Salt | Key intermediate in the metabolism of sugars and their transformation to nucleotides. Also a potential inhibitor for the heptose synthetase, an enzyme of the biosynthesis of the inner core region of lipopolysaccharides. Contains 1-2 equivalents of cyclohexylamine. Synonyms: Cyclohexanamine; [(2R,3S,4S,5S,6R)-6-[(1R)-1,2-dihydroxyethyl]-3,4,5-trihydroxyoxan-2-yl] dihydrogen phosphate; Cyclohexanamine--1-O-phosphono-alpha-D-manno-heptopyranose (1/1); (D-Glycero-?-D-manno-heptopyranosyl)-dihydogenphosphate, Cyclohexylammonium Salt; Cyclohexanamine (2R,3S,4S,5S,6R)-6-((R)-1,2-dihydroxyethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl phosphate. CAS No. 359435-45-3. Molecular formula: C13H28NO10P. Mole weight: 389.34. | |
| [D-Ile]3-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DIle-DLys-Pip; D-Phe-D-Phe-D-Ile-D-Lys-Pip; ffik-Pip; 1-(D-Phenylalanyl-D-phenylalanyl-D-isoleucyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid; D-Ile3-Difelikefalin; [D-Ile]3-Difelikefalin; [D-Ile3]-Difelikefalin; D-Ile-Difelikefalin; N1-(D-Phenylalanyl-D-phenylalanyl-D-isoleucyl-D-lysyl)-4-amino-4-piperidinecarboxylic acid; D-Phe-D-Phe-D-Ile-D-Lys-4-amino-4-piperidinecarboxylic acid. Grade: ≥95%. Molecular formula: C36H53N7O6. Mole weight: 679.85. | |
| Dimethylmethoxy chromanol | Dimethylmethoxy chromanol Synonyms: 3,4-Dihydro-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-ol; 3,4-Dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran; CR 6; Lipochroman; Lipochroman 6. Molecular Formula: C12H16O3. Molecular Weight: 208.25. Description: Dimethylmethoxy chromanol scavenges free radicals with a double scavenging effect on RNS and RCS. It effectively clears singlet oxygen activity, reduces lipid peroxidation in human cells, resists photooxidation, protects DNA, improves cell vitality, and reduces oxidative stress. Main Use: It is particularly suitable for use in anti-aging and anti-premature aging products. Grade: ≥98% CAS: 83923-51-7 | |
| [disulphonic-acid]-Desmopressin | An impurity of Desmopressin. Desmopressin is a synthetic analogue of the hormone vasopressin, used to treat conditions such as central diabetes insipidus, nocturnal enuresis (bedwetting), and certain bleeding disorders like hemophilia A and von Willebrand disease. Synonyms: Mpr(SO3H)-Tyr-Phe-Gln-Asn-Cys(acid)-Pro-DArg-Gly-NH2; Mpr(SO3H)-YFQN-Cys(acid)-P-DArg-G-NH2; Mpa(SO3H)-Tyr-Phe-Gln-Asn-Cys(SO3H)-Pro-D-Arg-Gly-NH2; deamino-Cys(SO3H)-Tyr-Phe-Gln-Asn-Cys(SO3H)-Pro-D-Arg-Gly-NH2; Deamino-cysteinyl(SO3H)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl(SO3H)-L-prolyl-D-arginyl-glycinamide. Grade: ≥95%. Molecular formula: C46H66N14O18S2. Mole weight: 1167.23. | |
| (DL)-3-O-Methyldopa (Levodopa Related Compound B) | Impurity of Levodopa. Synonyms: 3-Methoxytyrosine; 3-(4-Hydroxy-3-methoxyphenyl)alanine; 3-(Methoxy)-dl-tyrosine; 4-Hydroxy-3-methoxyphenylalanine; DL-3-Methoxy-4-hydroxyphenylalanine. Grade: > 95%. CAS No. 7636-26-2. Molecular formula: C10H13NO4. Mole weight: 211.22. | |
| (D-Leu6,Pro-NHEt9)-LHRH (4-9) | (D-Leu6,Pro-NHEt9)-LHRH (4-9). Synonyms: L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide; L-Prolinamide, L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-. Grade: ≥95%. CAS No. 202333-85-5. Molecular formula: C37H62N10O8. Mole weight: 774.95. | |
| [D-Lys(Ac)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(Ac)-Pip; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-acetyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid; N1-(D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-acetyl-D-lysyl)-4-amino-4-piperidinecarboxylic acid; D-Phe-D-Phe-D-Leu-D-Lys(Ac)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(Ac)-Pip; Difelikefalin acetate impurity 15; Lys4(Ac)-Difelikefalin; D-Lys4(Ac)-Difelikefalin; Lys(Ac)-Difelikefalin; Lys(Ac)4-Difelikefalin; [Lys(Ac)]4-Difelikefalin. Grade: ≥95%. Molecular formula: C38H55N7O7. Mole weight: 721.89. | |
| [D-Lys(EA)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(EA)-4-Piperidinecarboxylic acid; 4-Amino-1-((R)-2-((R)-2-((R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylpentanamido)-6-((2-aminoethyl)amino)hexanoyl)piperidine-4-carboxylic acid; Difelikefalin impurity 10; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-(2-aminoethyl)-D-lysyl)-4-aminopiperidine-4-carboxylic acid; D-Phe-D-Phe-D-Leu-D-Lys(EA)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(EA)-Pip; D-Lys4(EA)-Difelikefalin; D-Lys(EA)4-Difelikefalin. Grade: ≥95%. CAS No. 2219351-44-5. Molecular formula: C38H58N8O6. Mole weight: 722.92. | |
| [D-Lys(Ipr)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(Ipr)-4-Piperidinecarboxylic acid; Difelikefalin impurity 8; 1-[D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-(1-methylethyl)-D-lysyl]-4-amino-4-piperidinecarboxylic acid; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-isopropyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid; D-Phe-D-Phe-D-Leu-D-Lys(Ipr)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(Ipr)-Pip; D-Lys4(Ipr)-Difelikefalin; D-Lys(Ipr)4-Difelikefalin; 4-Amino-1-((R)-2-((R)-2-((R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylpentanamido)-6-(isopropylamino)hexanoyl)piperidine-4-carboxylic acid. Grade: ≥95%. CAS No. 1024828-90-7. Molecular formula: C39H59N7O6. Mole weight: 721.93. | |
| [D-Lys(Me)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(Me)-4-Piperidinecarboxylic acid; Difelikefalin impurity 5; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-methyl-D-lysyl)-4-aminopiperidine-4-carboxylic acid; N1-(D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-methyl-D-lysyl)-4-amino-4-piperidinecarboxylic acid; D-Phe-D-Phe-D-Leu-D-Lys(Me)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(Me)-Pip; D-Lys4(Me)-Difelikefalin; D-Lys(Me)4-Difelikefalin. Grade: ≥95%. CAS No. 1024828-78-1. Molecular formula: C37H55N7O6. Mole weight: 693.88. | |
| [D-Lys(Propylamine)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(Propylamine)-4-Piperidinecarboxylic acid; 4-Amino-1-((R)-2-((R)-2-((R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylpentanamido)-6-((3-aminopropyl)amino)hexanoyl)piperidine-4-carboxylic acid; Difelikefalin impurity 11; D-Phe-D-Phe-D-Leu-D-Lys(Propylamine)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(Propylamine)-Pip; D-Lys4(Propylamine)-Difelikefalin; D-Lys(Propylamine)4-Difelikefalin; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-(3-aminopropyl)-D-lysyl)-4-aminopiperidine-4-carboxylic acid. Grade: ≥95%. CAS No. 2219351-45-6. Molecular formula: C39H60N8O6. Mole weight: 736.94. | |
| [D-Lys(tBu)]4-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: DPhe-DPhe-DLeu-DLys(tBu)-4-Piperidinecarboxylic acid; Difelikefalin impurity 16; 1-(N2-D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-(tert-butyl)-D-lysyl)-4-aminopiperidine-4-carboxylic acid; N1-(D-Phenylalanyl-D-phenylalanyl-D-leucyl-N6-(tert-butyl)-D-lysyl)-4-amino-4-piperidinecarboxylic acid; D-Phe-D-Phe-D-Leu-D-Lys(tBu)-4-amino-4-piperidinecarboxylic acid; ffl-DLys(tBu)-Pip; D-Lys4(tBu)-Difelikefalin; D-Lys(tBu)4-Difelikefalin. Grade: ≥95%. Molecular formula: C40H61N7O6. Mole weight: 735.96. | |
| (D)-(+)-Neopterin | Neopterin, a pyrazino-pyrimidine compound derived from GTP, n is a precursor of tetrahydrobiopterin and can be used as a biochemical marker indicative of cell proliferation. Neopterin is synthesized in response to interferon-γ stimulation, and used as a marker of T helper cell-induced immune activation. Neopterin is also an indicator of oxidative stress, and modulates the effects of reactive oxygen species (ROS). Synonyms: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone; Neopterin; 2-Amino-4-hydroxy-6-(1,2,3-trihydroxypropyl)pteridine; 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)-4(8H)-pteridone; 6-D-erythro-Neopterin; D-(+)-Neopterin; D-erythro-Neopterin. Grade: ≥98% by HPLC. CAS No. 2009-64-5. Molecular formula: C9H11N5O4. Mole weight: 253.21. | |
| [D-Orn6]-Cetrorelix | [D-Orn6]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: D-Orn6-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Orn-Leu-Arg-Pro-D-Ala-NH2; (S)-1-(((S)-2-((S)-2-((S)-2-((R)-2-((R)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanamido)-3-(pyridin-3-yl)propanamido)-3-hydroxypropanamido)-3-(4-hydroxyphenyl)propanamido)-5-aminopentanoyl)-L-leucyl-L-arginyl)-N-((R)-1-amino-1-oxopropan-2-yl)pyrrolidine-2-carboxamide. Molecular formula: C69H91ClN16O13. Mole weight: 1388.04. | |
| [D-Phe12]-Bombesin | [D-Phe12]-Bombesin is a bombesin receptor antagonist inhibiting bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Synonyms: [D-Phe12]-Bombesin; 12-Phe-bombesin; Bombesin, phe(12)-; PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2; Bombesin, phenylalanine(12)-; (D-Phe12)-Bombesin; Bombesin, 12-D-phenylalanine; AKOS024456850; PD079209. CAS No. 108437-87-2. Molecular formula: C74H112N22O18S. Mole weight: 1629.9. | |
| [D-Phe12,Leu14]-Bombesin | [D-Phe12,Leu14]-Bombesin is a bombesin receptor antagonist. It inhibits bombesin binding to rat brain (IC50 = 2 μM), inhibits amylase release in vitro (IC50 = 4 μM), and attenuates bombesin-mediated suppression of food intake in vivo. Synonyms: [D-Phe12,Leu14]-Bombesin; 108437-88-3; PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-LEU-NH2; (D-Phe12,Leu14)-Bombesin; AKOS024457621; PD079499; HY-103287; CS-0027153. CAS No. 108437-88-3. Molecular formula: C75H114N22O18. Mole weight: 1610.9. | |
| [D-Phe12,Leu14]-Bombesin acetate | [D-Phe12,Leu14]-Bombesin is a bombesin receptor antagonist. It inhibits bombesin binding to rat brain (IC50 = 2 μM), inhibits amylase release in vitro (IC50 = 4 μM), and attenuates bombesin-mediated suppression of food intake in vivo. Molecular formula: C77H118N22O20. Mole weight: 1671.89. | |
| [D-Phe((βR)-Me)]1-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: beta-RMe-DPhe-DPhe-DLeu-DLys-4-Piperidinecarboxylic acid; 4-Amino-1-((R)-6-amino-2-((R)-N-((2R,3R)-2-amino-3-phenylbutanoyl)-2-((R)-2-amino-3-phenylpropanamido)-4-methylpentanamido)hexanoyl)piperidine-4-carboxylic acid; 4-Amino-1-(((2R,3R)-2-amino-3-phenylbutanoyl)-D-phenylalanyl-D-leucyl-D-lysyl)piperidine-4-carboxylic acid; Difelikefalin impurity 9; [beta-RMe-D-Phe]1-Difelikefalin; [β-(R)-Me-D-Phe]1-Difelikefalin; [D-Phe(βR-Me)]1-Difelikefalin. Grade: ≥95%. CAS No. 2756592-19-3. Molecular formula: C37H55N7O6. Mole weight: 693.88. | |
| [D-Phe(EA)]1-Difelikefalin | An impurity of Difelikefalin. Difelikefalin is a kappa opioid receptor (KOR) agonist used to treat moderate to severe pruritus (itching) associated with chronic kidney disease (CKD) in patients undergoing hemodialysis. Synonyms: Ethylamine-DPhe-DPhe-DLeu-DLys-4-Piperidinecarboxylic acid; 4-Amino-1-((2R,5R,8R,11R)-14-amino-2-(4-aminobutyl)-8,11-dibenzyl-5-isobutyl-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oyl)piperidine-4-carboxylic acid; 4-Amino-1-((2-aminoethyl)-D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl)piperidine-4-carboxylic acid; Difelikefalin impurity 12; D-Phe(EA)-D-Phe-D-Leu-D-Lys-4-amino-4-piperidinecarboxylic acid; f(EA)flk-Pip; D-Phe1(EA)-Difelikefalin; D-Phe(EA)1-Difelikefalin. Grade: ≥95%. CAS No. 2219351-61-6. Molecular formula: C38H58N8O6. Mole weight: 722.92. | |
| (D)-PPA 1 | PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo. Synonyms: H-D-Asn-D-Tyr-D-Ser-D-Lys-D-Pro-D-Thr-D-Asp-D-Arg-D-Gln-D-Tyr-D-His-D-Phe-OH. Grade: ≥95%. CAS No. 1620813-53-7. Molecular formula: C70H98N20O21. Mole weight: 1555.67. | |
| [D-Pro9]-Cetrorelix | [D-Pro9]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-Tyr-DCit-Leu-Arg-DPro-DAla-NH2; D-Pro9-Cetrorelix; [D-Pro]9-Cetrorelix; D-Pro(9)-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-D-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-D-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-75-8. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| [D-Ser4]-Cetrorelix | [D-Ser4]-Cetrorelix is a derivative of Cetrorelix, a gonadotropin-releasing hormone antagonist that can be used in the treatment of prostate and breast cancers. Synonyms: D-Ser4-Cetrorelix; (D-Ser4)-Cetrorelix; D-Ser(4)-Cetrorelix; D-Ser-Cetrorelix; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-D-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-D-seryl-L-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide. Grade: ≥95%. CAS No. 3031679-89-4. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06. | |
| [D-Thr5]-Liraglutide | [D-Thr5]-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: D-Thr5-Liraglutide; H-His-Ala-Glu-Gly-D-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(1)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.palmitoyl-Glu(1)-OH. Molecular formula: C172H265N43O51. Mole weight: 3751. | |
| [D-Trp11]-Neurotensin | [D-Trp11]-Neurotensin is an analogue of Neurotensin (NT). It is a selective antagonist of NT in perfused rat hearts but behaves as a full agonist in guinea pig atria and rat stomach strips. [D-Trp11]-Neurotensin can also inhibit NT-induced hypotension. CAS No. 73634-68-1. Molecular formula: C80H122N22O19. Mole weight: 1695.96. | |
| [D-Trp34]-Neuropeptide Y | [D-Trp34]-Neuropeptide Y is a potent and selective NPY Y(5) receptor agonist (pEC50= 7.82, 6.28, 6.44 and > 6 at rat Y5, Y4, Y1 and Y2 receptors respectively), with > 26-fold, > 1000-fold and > 1000-fold selectivity over Y1, Y2 and Y4 receptors respectively. Unlike the prototype selective NPY Y(5) receptor agonist [D-Trp(32)]NPY, [D-Trp(34)]NPY markedly increases food intake in rats, an effect that is blocked by the selective NPY Y(5) receptor antagonist CGP 71683A. Synonyms: Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-D-Trp-Arg-Tyr-NH2. CAS No. 153549-84-9. Molecular formula: C196H289N55O56. Mole weight: 4311.77. | |
| [D-Trp 7,9,10]-Substance P | [D-Trp 7,9,10]-Substance P is a substance P analog that blocks activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors. Synonyms: Gpantagonist-2A; GPAnt-2 analog. CAS No. 89430-38-6. Molecular formula: C79H105N21O13S. Mole weight: 1588.89. | |
| (E)-1-(2-Aminoethylidene)-6-methoxyindan | (E)-1-(2-Aminoethylidene)-6-methoxyindan is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: (E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethanamine; (2E)-2-(2,3-Dihydro-6-methoxy-1H-inden-1-ylidene)ethanamine. CAS No. 178676-73-8. Molecular formula: C12H15NO. Mole weight: 189.25. | |
| (E)-1-Benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium Chloride | (E)-1-Benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridinium Chloride is used as a reactant in the preparation of Donepezil, which is a highly specific reversible acetylcholinesterase (AChE) inhibitor used to treat moderate to severe Alzheimer's disease. Synonyms: 1-Benzyl-4-[(E)-(5,6-dimethoxy-1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl]pyridinium chloride; Pyridinium, 4-[(E)-(1,3-dihydro-5,6-dimethoxy-1-oxo-2H-inden-2-ylidene)methyl]-1-(phenylmethyl)-, chloride (1:1). Grade: ≥95%. CAS No. 1188913-39-4. Molecular formula: C24H22ClNO3. Mole weight: 407.89. | |
| (E)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethylamine | (E)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)ethylamine is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the preparation of ramelteon. Synonyms: 2-[(8E)-1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-ylidene]ethan-1-amine; 2-[(E)-1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene]ethylamine. Grade: >95%. CAS No. 196597-61-2. Molecular formula: C13H15NO. Mole weight: 201.26. | |
| (E)-2-(5-(cyanoimino)-1-propylpyrrolidin-2-yl)acetic acid | An impurity of Pramipexole which is an agonist of dopamine receptor D2, D3 and D4, especially used as D2-receptor agonist. Synonyms: N-Propyl-2S-cyanimidopyrrolidine-5-acetic Acid; Pramipexole Related Compound. CAS No. 1373869-89-6. Molecular formula: C10H15N3O2. Mole weight: 209.24. | |
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