BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| LS-tetrasaccharide c | LS-tetrasaccharide c is an extraordinary biomedical compound, bestowed with the exceptional ability to impede ceramide glycosyltransferase, a vital actor implicated in the relentless march of tumor propagation and metastasis. Alternative Names: LSTc; Sialyllacto-N-tetraose c; a-NeuNAc-(2-6)-b-Gal-(1-4)-b-GlcNAc-(1-3)-b-Gal-(1-4)-Glc; N-Acetylneuraminyllacto-N-neo-tetraose c; alpha-Neu5Ac-(2->6)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-D-Glcp; 5-Acetamido-3,5-dideoxy-D-glycero-alpha-D-beta-non-2-ulonosyl-(2->6)-beta-D-galactosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucosyl-(1->3)-beta-D-galactosyl-(1->4)-D-glucose; O-(N-Acetyl-α-neuraminosyl)-(2→6)-O-β-D-galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-D-glucose; SLNT-c. Grades: 95%. CAS No. 64003-55-0. Molecular formula: C37H62N2O29. Mole weight: 998.88. |  |
| L-Sulforaphane | L-Sulforaphane is a compound with isothiocyanate group found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbages. It has been shown to regulate phase II detoxifying enzymes and induce cell cycle arrest or apoptosis in malignant cells in vitro and in vivo, thus can be potentially used as an antioxidant and anticancer agent. Uses: Anticarcinogenic agents. Alternative Names: (R)-Sulforaphane; 4-Methylsulfinylbutyl isothiocyanate. Grades: ≥98%. CAS No. 142825-10-3. Molecular formula: C6H11NOS2. Mole weight: 177.3. | |
| L-Tagatose | L-Tagatose, derived from d-tagatose, is a low-calorie natural sweetener used in studying diseases related to high blood sugar levels, such as diabetes. Alternative Names: Tagatose, L-; keto-L-tagatose; L-lyxo-2-Hexulose. CAS No. 17598-82-2. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L(+)-Tartaric acid | L(+)-Tartaric acid is used as an acidulant in beverages, confectionery, foods and pharmaceutical formulations. It is also used as a sequestering agent and antioxidant synergist. Alternative Names: [R-(R*,R*)]-2,3-Dihydroxybutanedioic acid; (+)-(2R,3R)-Tartaric Acid; (+)-(R,R)-Tartaric Acid; (+)-L-Tartaric Acid; (+)-Tartaric Acid; (2R,3R)-(+)-Tartaric Acid; (2R,3R)-2,3-Dihydroxysuccinic Acid; (2R,3R)-Tartaric Acid; (R,R)-(+)-Tartaric Acid; NSC 62778; Tartaric Acid; Threaric Acid. Grades: >95%. CAS No. 87-69-4. Molecular formula: C4H6O6. Mole weight: 150.09. | |
| L-tBuO-Pal-Glu(OSu)-OtBu | L-tBuO-Pal-Glu(OSu)-OtBu is an intermediate in the synthesis of Degludec. Degludec is a long-acting basal insulin with the potential for the treatment of type 1 and type 2 diabetes. Alternative Names: Degludec Side Chain. CAS No. 843666-26-2. Molecular formula: C33H56N2O9. Mole weight: 624.8. | |
| L-Tetrahydrofolic Acid | Tetrahydrofolic acid is a folic acid derivative. It is a cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids. Uses: A cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids. Alternative Names: N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; (-)-L-5,6,7,8-Tetrahydrofolic Acid; THFA; Tetrahydropteroylglutamic Acid. Grades: ≥70% (when packaged). CAS No. 135-16-0. Molecular formula: C19H23N7O6. Mole weight: 445.43. | |
| L-Threonic acid | L-Threonic acid is an esteemed biomedical compound, used for studying the formidable adversaries of oxidative stress and neurodegenerative disorders. Remarkably, its antioxidant prowess studys cellular detriments and assuages inflammation affiliated with the onerous triad of Alzheimer's, Parkinson's and cardiovascular afflictions. Alternative Names: Butanoic acid, 2,3,4-trihydroxy-, (2R,3S)-; Butanoic acid, 2,3,4-trihydroxy-, [R-(R*,S*)]-; Threonic acid, L-. CAS No. 7306-96-9. Molecular formula: C4H8O5. Mole weight: 136.10. | |
| L-threo-sphingosine (d18:1) | L-threo-Sphingosine (d18:1), an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol % making it a slightly more potent inhibitor compared to D-erythro-sphingosine (50% inhibition at 2.8 mol %) or other analogs of shorter alkyl chain length. Alternative Names: (2S,3S,4E)-2-aminooctadec-4-ene-1,3-diol; 3-L-4-Sphingenine. Grades: >98%. CAS No. 25695-95-8. Molecular formula: C18H37NO2. Mole weight: 299.49. | |
| L-Thyroxine | L-Thyroxine is a synthetic form of thyroxine and a hormone replacement drug. Alternative Names: Levothyroxine; NSC 36397; NSC36397; NSC-36397. Grades: >98%. CAS No. 51-48-9. Molecular formula: C15H11I4NO4. Mole weight: 776.87. | |
| L-Thyroxine sodium salt pentahydrate | L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints. It was also used to study the light-induced hormone conversion of T4 to T3 in regulation of photoperiodic response of gonads in Japanese quail. Alternative Names: Sodium levothyroxine pentahydrate. Grades: >98%. CAS No. 6106-7-6. Molecular formula: C15H20I4NNaO9. Mole weight: 888.93. | |
| L-Tyrosine disodium salt dihydrate | L-Tyrosine disodium salt dihydrate. Alternative Names: Tyrosine disodium dihydrate; L-Tyrosine, disodium salt, dihydrate. CAS No. 122666-87-9. Molecular formula: C9H9NO3Na2.2H2O. Mole weight: 261.18. | |
| Lubabegron | Lubabegron is a β3-adrenoreceptor agonist. Uses: Β3-adrenoreceptor agonist. Alternative Names: LY488756; LY-488756; LY 488756; Lubabegron; 2-[4-[2-[[(2S)-2-hydroxy-3-(2-thiophen-2-ylphenoxy)propyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carbonitrile. Grades: ≥98%. CAS No. 391920-32-4. Molecular formula: C29H29N3O3S. Mole weight: 499.62. | |
| Lubiprostone Related Compound 3 | Lubiprostone Related Compound 3 is a biomedicine related to Lubiprostone, a drug used in the treatment of gastrointestinal disorders. Grades: > 95%. CAS No. 1263283-38-0. Molecular formula: C20H32F2O5. Mole weight: 390.47. | |
| Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity | Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity. Alternative Names: Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity; LUBRICATING OIL BASE STOCKS); Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity Baseoil-unspecified; neutral oil, C20-50 hydrotreated, h. Grades: 95%. CAS No. 72623-85-9. | |
| Lucifer yellow iodoacetamide dipotassium salt | Lucifer yellow iodoacetamide dipotassium salt is a thiol-reactive fluorescent polar tracer. CAS No. 176182-05-1. Molecular formula: C16H12IK2N3O9S2. Mole weight: 659.51. | |
| Lucigenin | Lucigenin is a fluoerscent probe that exhibits a bluish-green fluorescence in the presence of superoxide and chloride. It can be used to detect superoxide production by enzymatic and cellular sources. Alternative Names: 10,10'-dimethyl-9,9'-biacridinium, dinitrate; N,N'-Dimethyl-9,9'-biacridinium dinitrate; Lucigenin Nitrate; NSC 151912; Bis(N-methylacridinium) Nitrate; 9,9'-Bis(N-methylacridinium nitrate). Grades: ≥95%. CAS No. 2315-97-1. Molecular formula: C28H22N2.2NO3. Mole weight: 510.50. | |
| Lucinactant | Lucinactant (trade name Surfaxin) is a liquid medication used to treat Infant Respiratory Distress Syndrome in infants. A synthetic human lung surfactant consisting of peptide KL4, dipalmitoylphosphatidylcholine, palmitoyloleoylphosphatidylglycerol, and palmitic acid. Alternative Names: ATI 02; KL-surfactant; KL4-surfactant; Surfaxin. Grades: 98%. CAS No. 825600-90-6. Molecular formula: C128H242N26O24. Mole weight: 2529.5. | |
| Lumacaftor | Lumacaftor is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF). Lumacaftor may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Lumacaftor defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage. Alternative Names: VX-809; VX809; VX 809; VRT 826809; VRT826809; VRT-826809. Grades: ≥98%. CAS No. 936727-05-8. Molecular formula: C24H18F2N2O5. Mole weight: 452.41. | |
| Lumasiran | Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Alternative Names: ALN-G01; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) (1:1). Grades: 98% by SEC-HPLC. CAS No. 1834610-13-7. Molecular formula: C530H712F10N173O320P43S6. Mole weight: 16,340 Da. | |
| Lumasiran sodium | Lumasiran sodium is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Alternative Names: ALN-G01 sodium; Oxlumo; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] sodium salt, complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) sodium salt (1:21:1:22). CAS No. 1834612-06-4. Molecular formula: C530H669F10N173O320P43S6Na43. Mole weight: 17,286 Da. | |
| Luminespib | Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins. Alternative Names: Luminespib; AUY-922; AUY922; AUY 922; NVP-AUY-922; NVP-AUY922; VER-52296; VER52296; VER 52296. Grades: >98%. CAS No. 747412-49-3. Molecular formula: C26H31N3O5. Mole weight: 465.54. | |
| Luminol | It is a chemiluminescent reagent and indicator, commonly used in chemiluminescent immunoassay, such as metal cations and blood detection. Alternative Names: 3-Aminophthalhydrazide; 5-amino-2,3-dihydrophthalazine-1,4-dione; 5-Amino-2,3-dihydro-1,4-phthalazinedione; 5-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dione; 3-Aminophthalic acid hydrazide; 5-Amino-1,4-dihydroxyphthalazine; NSC 5064. Grades: ≥ 98 %. CAS No. 521-31-3. Molecular formula: C8H7N3O2. Mole weight: 177.16. | |
| Lumiracoxib | Lumiracoxib is a novel, selective COX-2 inhibitor. Uses: Cyclooxygenase 2 inhibitors. Alternative Names: CGS-35189; CGS 35189; CGS35189; COX-189; COX189; COX 189; Lumiracoxib; trade name: Prexige. Grades: > 95%. CAS No. 220991-20-8. Molecular formula: C15H13ClFNO2. Mole weight: 293.72. | |
| Lupulone C | Lupulone C is a natural compound which can be isolated from Humulus lupulus, etc. Alternative Names: 4-hydroxy-2-(2-hydroxypropan-2-yl)-7-(3-methylbutanoyl)-5,5-bis(3-methylbut-2-enyl)-2,3-dihydro-1-benzofuran-6-one. Grades: 95%. CAS No. 613683-50-4. Molecular formula: C26H38O5. Mole weight: 430.58. | |
| Lurbinectedin | Lurbinectedin, also known as PM01183, is a synthetic tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogue with potential antineoplastic activity. DNA minor groove-binding agent PM01183 covalently binds to residues lying in the minor groove of DNA, which may result in delayed progression through S phase, cell cycle arrest in the G2/M phase and cell death. Alternative Names: PM-01183; PM 01183; PM01183. Lurbinectedin. CAS No. 497871-47-3. Molecular formula: C41H44N4O10S. Mole weight: 784.881. | |
| Lutein dipalmitate | Lutein dipalmitate is extracted from the dried petals of yellow marigold flowers. Alternative Names: Helenien; Xantofyl Palmitate; Adaptinol. Grades: > 95%. CAS No. 547-17-1. Molecular formula: C72H116O4. Mole weight: 1045.69. | |
| Luteolinidol chloride | Luteolinidol chloride is a highly esteemed natural compound, aiding in studying an array of malignancies, cardiovascular maladies and enigmatic neurodegenerative enfeeblements. Alternative Names: 1-Benzopyrylium,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, chloride (1:1). CAS No. 1154-78-5. Molecular formula: C15H11ClO5. Mole weight: 306.70. | |
| Luxeptinib | Luxeptinib is a tyrosine kinase inhibitor, with antineoplastic activity. Alternative Names: N-{3-fluoro-4-[7-(4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-N'-(2,4,6-trifluorophenyl)urea; NSC-791692; Urea, N-[4-[2,3-dihydro-7-(5-methyl-1H-imidazol-2-yl)-1-oxo-1H-isoindol-4-yl]-3-fluorophenyl]-N'-(2,4,6-trifluorophenyl)-. CAS No. 1616428-23-9. Molecular formula: C25H17F4N5O2. Mole weight: 495.43. | |
| Luzindole | Luzindole is a melatonin receptor antagonist which preferentially targets MT1B. Alternative Names: Luzindole, N-0774, N0774, N 0774, N-acetyl-2-benzyltryptamine. Grades: ≥99% by HPLC. CAS No. 117946-91-5. Molecular formula: C19H20N2O. Mole weight: 292.38. | |
| L-Valacyclovir Hydrochloride | Valaciclovir HCl is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Alternative Names: Valacyclovir hydrochloride; Valacyclovir HCl. Grades: >98%. CAS No. 124832-27-5. Molecular formula: C13H20N6O4.HCl. Mole weight: 360.8. | |
| L-Valine hydrochloride | L-Valine hydrochloride. Alternative Names: L-VALINE HYDROCHLORIDE SOLUTION; L-Valine hydrochloride; L-Valine solution hydrochloride. CAS No. 17498-50-9. Molecular formula: C5H11NO2.HCl. Mole weight: 153.61. | |
| L-Vinylglycine | L-Vinylglycine is a non-proteinogenic L-alpha-amino acid and an inhibitor of aspartate aminotransferase. Alternative Names: (S)-2-Aminobut-3-enoic acid; Vinylglycine; 3-Butenoic acid, 2-amino-, (2S)-; (2S)-2-aminobut-3-enoic acid. Grades: 95%. CAS No. 70982-53-5. Molecular formula: C4H7NO2. Mole weight: 101.105. | |
| LXH254 | LXH254 is a pan-Raf inhibitor developed for the treatment of solid tumors. Uses: Antineoplastic agents. Alternative Names: LXH-254; LXH 254; N-[3-[2-(2-Hydroxyethoxy)-6-morpholin-4-ylpyridin-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide. Grades: ≥98%. CAS No. 1800398-38-2. Molecular formula: C25H25F3N4O4. Mole weight: 502.49. | |
| LY2109761 | LY2109761 is a novel inhibitor of TGF-β receptor type I / type II kinases (IC50 = 69 nM), displaying antitumor activity. In vivo study demonstrated that LY2109761, in combination with gemcitabine, significantly reduced the tumor burden, prolonged survival, and reduced spontaneous abdominal metastases. Alternative Names: LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine. Grades: >98%. CAS No. 700874-71-1. Molecular formula: C26H27N5O2. Mole weight: 441.52. | |
| LY 233536 | LY 233536 is a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist, but few detailed information has been published yet. Alternative Names: LY 233536; LY-233536; LY233536; (3R-(3alpha,4aalpha,6beta,8aalpha))-decahydro-6-(1H-tetrazol-5-ylmethyl)- 3-Isoquinolinecarboxylic acid. Grades: 98%. CAS No. 136845-59-5. Molecular formula: C12H19N5O2. Mole weight: 265.32. | |
| LY-2456302 | LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist (Ki = 0.807 nM) with favorable pharmacokinetic and pharmacodynamic properties to evaluate the role of KOR in preclinical models of alcoholism. Alternative Names: 4-[4-[[(2S)-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl]phenoxy]-3-fluorobenzamide; 3-fluoro4-(4-((2-(3,5-dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide; LY2456302; CERC-501; LY 2456302; CERC 501; LY-2456302; CERC501. CAS No. 1174130-61-0. Molecular formula: C26H27FN2O2. Mole weight: 418.5. | |
| LY2606368 | LY2606368 is a potent and selective ATP competitive inhibitor(IC50=1.5 nM in SW1990 cell) of the Chk1 protein kinase. Alternative Names: LY-2606368; LY 2606368. Grades: >98%. CAS No. 1234015-52-1. Molecular formula: C18H19N7O2. Mole weight: 365.397. | |
| LY2606368 dihydrochloride | The dihydrochloride salt form of LY2606368 which also known as prexasertib, is an inhibitor of checkpoint kinase 1 and has potential effect in antineoplastic. It is still under Phase II clinical trial against breast cancer and some other sorts of cancers. Uses: The dihydrochloride salt form of ly2606368 which also known as prexasertib, is an inhibitor of checkpoint kinase 1 and has potential effect in antineoplastic. Alternative Names: UNII-9RFT476U2L; 9RFT476U2L; LY2606368 (dihydrochloride); 1234015-54-3; HY-18174A; CS-3507; CS 3507; CS3507; LY2606368; LY 2606368; LY-2606368. Grades: 98%. CAS No. 1234015-54-3. Molecular formula: C18H21Cl2N7O2. Mole weight: 438.31. | |
| LY3130481 | LY3130481, a benzothiazol derivative, has been found to be the first AMPA receptor antagonist that could be probably effective in studies of epilepsy. It has just been planed a Phase I trial by Cerecor. Alternative Names: LY3130481; LY-3130481; LY 3130481; CERC-611; CERC611; CERC 611. (S)-6-(1-(1-(5-(2-hydroxyethoxy)pyridin-2-yl)-1H-pyrazol-3-yl)ethyl)benzo[d]thiazol-2(3H)-one. Grades: 98%. CAS No. 1610802-47-5. Molecular formula: C19H18N4O3S. Mole weight: 382.44. | |
| LY 379268 | LY 379268 is a group II mGlu receptor agonist with EC50 values of 2.69 and 4.48 nM for hmGlu2 and hmGlu3. Some research shows that LY379268 can attenuate cocaine-induced increases in DA in nonhuman primates. Alternative Names: LY379268; LY 379268; LY-379268; (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid. Grades: ≥99% by HPLC. CAS No. 191471-52-0. Molecular formula: C7H9NO5. Mole weight: 187.15. | |
| LY451395 | Incubation of LY451395 with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies of the preclinical species. LY404187 and LY451395 reverses the central effects of an acutely intoxicating dose of ethanol in the rat. LY451395 significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward. Alternative Names: Mibampator; LY 451395; LY-451395. Grades: >98%. CAS No. 375345-95-2. Molecular formula: C21H30N2O4S2. Mole weight: 438.6. | |
| Lycasin | It is used as a bulk sweetener in oral preparations, either alone or in combination with other excipients such as sorbitol. It is also used as a suspending agent in oral liquids as a substitute for sucrose syrup because it is viscous, noncariogenic and has a low calorific value. Alternative Names: Maltitol solution; E965; hydrogenated glucose syrup; Finmalt L; Lycasin HBC; Lycasin 80/55; Maltisorb 75/75; Maltisweet 3145; maltitol syrup; Liquid Maltitol. CAS No. 9053-46-7. | |
| LYCOPANE | LYCOPANE. Alternative Names: LYCOPANE. CAS No. 45316-02-7. Molecular formula: C40H82. | |
| LYCOPODIUM | LYCOPODIUM. Alternative Names: CLUB MOSS SPORES; LYCOPODIUM; LYCOPODIUM POWDER; LycopodiumLLLlycopodium; lycopodium oil; Lycopodium from Lycopodium clavatum; Spores of lycopodium clavatum. Grades: powder. CAS No. 8023-70-9. Molecular formula: (Club Moss Spores). | |
| Lymecycline | Lymecycline is a tetracycline broad-spectrum antibiotic against Propionibacterium acnes which is central to the activation of the perifollicular inflammation. Uses: A semi-synthetic antibiotic related to tetracycline. antibacterial. Alternative Names: Tetracyclinemethylene lysine; N-lysinomethyltetracycline; Armyl; Mucomycin; N6-[[(4S)-4β-(Dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,6α,10,12,12aβ-pentahydroxy-6-methyl-1,11-dioxonaphthacen-2-yl]carbonylaminomethyl]-L-lysine; Tetralisal; Tetralysal. Grades: 95%. CAS No. 992-21-2. Molecular formula: C29H38N4O10. Mole weight: 602.63. | |
| Lys05 | Lys05, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth. Alternative Names: LYS-05 HCl; LYS05; LYS-05; Lys01 trihydrochloride; Lys01 3HCl; N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine trihydrochloride. CAS No. 1391426-24-6. Molecular formula: C23H26Cl5N5. Mole weight: 549.75. | |
| Lys-γ3-MSH | Lys-γ3-MSH, a melanocortin peptide derived from the C-terminal of the 16?kDa fragment of POMC, potentiates the steriodogenic action of corticotrophin on the adrenal cortex, possibly via the MC3 receptor. CAS No. 156159-18-1. Molecular formula: C128H193N45O39S. Mole weight: 3018.27. | |
| Lysine acetylsalicylate | Lysine acetylsalicylate. Alternative Names: Lysine, 2-(acetyloxy)benzoate (1:1); DL-Lysine acetylsalicylate; DL-Lysine, mono[2-(acetyloxy)benzoate]; Benzoic acid, 2-(acetyloxy)-, compd. with DL-lysine (1:1); Benzoic acid, 2-(acetyloxy)-, compd. with lysine (1:1); Lysine, mono[2-(acetyloxy)benzoate]; 2,6-diaminohexanoic acid compound with 2-acetoxybenzoic acid (1:1); DL-Lysine acetylsalicylate; DL-Lysine aspirin salt; Acelysin; Acelysine; Acetylsalicylic acid DL-lysine salt; Acetylsalicylic acid dl-lysine salt; Acetylsalicylic acid lysine salt; Asalis; Aspegic; Aspidol; Aspirin DL-lysine; Aspirin lysine salt; Aspirindl-lysine; Aspirisine; Aspisol; Atselizin; Cogla; Delgesic; Egicalm; Laboprin; LAS; Lysal; Lysine monosalicylate acetate; Lysini racemici acetylsalicylase; o-Acetylsalicylic acid D,L-lysine salt; Quinvet; Solpirin; Venopirin; Vetalgina; Vetalgine. CAS No. 62952-06-1. Molecular formula: C9H8O4.C6H14N2O2. Mole weight: 326.35. | |
| LYSINE OXIDASE FROM TRICHODERMA VIRIDE | LYSINE OXIDASE FROM TRICHODERMA VIRIDE. Grades: 95%. CAS No. 70132-14-8. | |
| Lyso PA | Lyso PA is an endogenous agonist for LPA1 and LPA2 receptors. LPA has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate and induces cell migration of cancer and non-cancer cells. Alternative Names: 1-Oleoyl-sn-glycerol 3-phosphate sodium salt; 3-sn-Lysophosphatidic acid; 1-oleoyl sodium salt; LPA sodium salt. Grades: 98%. CAS No. 22556-62-3. Molecular formula: C21H40NaO7P. Mole weight: 458.5. | |
| Lyso-phosphatidylcholine, LPC (egg) | Lyso-phosphatidylcholine, LPC (egg), an essential phospholipid, exhibits indispensable functions in maintaining cellular membrane integrity and functionality. Extensive research has explored its promising therapeutic attributes in alleviating cardiovascular pathologies, hepatic maladies, and neurological ailments. Alternative Names: L-α-lysophosphatidylcholine; Egg Lyso PC. Grades: >98%. CAS No. 97281-36-2. Molecular formula: C24H50NO7P. Mole weight: 495.63. | |
| LysoSens Yellow / Blue DND-160 | LysoSens Yellow / Blue DND-160 is a ratiometric probe used for measurement of pH of acidic organelles. This LysoSens dye emits blue fluorescence in neutral environment and yellow fluorescence in acidic environment. Molecular formula: C20H22N4O3. Mole weight: 366.42. | |
| Lysostaphin | Lysostaphin is an antistaphylococcal agent. Lysostaphin has three enzyme activities, namely glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase. Alternative Names: Glycyl-glycine Endopeptidase; Lysostaphin from Staphylococcus staphylolyticus. Grades: ≥97%. CAS No. 9011-93-2. | |
| M 24 | M 24 is the first selective AT2 receptor agonist (Ki 0.4nM and 10.000 nM for AT2 and AT1 respectively). M 24 effects against endothelial inflammation and leukocyte adhesion both in vitro and in vivo. Alternative Names: M 24; M24; M-24; butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate. Grades: 98%. CAS No. 477775-14-7. Molecular formula: C23H29N3O4S2. Mole weight: 475.62. | |
| m27,3'-OGP3G (ARCA Cap Analog) | m27,3'-OGP3G (ARCA Cap Analog), renowned for its exceptional properties, is a cap analog. Its omnipresence is felt in various research arenas, permeating the realms of mRNA structure investigation, protein interactions exploration and viral replication mechanism elucidation. Alternative Names: mG(5')ppp(5')G; P-(5'-(3'-O-methyl)-7-methyl-guanosyl), P-(5'-(guanosyl))triphosphate; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-3'-O-methyl-, inner salt, P''→5'-ester with guanosine; 3'-O-Methyl-m7GpppG; ARCA; ARCA (anti-reverse cap analog); m27,3'OGpppG; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine. Grades: ≥95% by HPLC. CAS No. 400806-46-4. Molecular formula: C22H31N10O18P3. Mole weight: 816.46. | |
| m32.2.7GP3G (Trimethylated Cap Analog) | m32.2.7GP3G (Trimethylated Cap Analog) is an indispensable compound of paramount significance, meticulously employed for the purpose of synthesizing mRNA molecules. By judiciously interweaving this cap analog within the process of mRNA transcription, it bestows a marked amplification in translational efficiency, stability and the intricate realm of translation initiation. Alternative Names: G(5')ppp(5')G; P; -(5'-2,2,7-trimethyl-guanosyl) P; -(5'-(guanosyl))triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 123212-20-4. Molecular formula: C23H33N10O18P3(free acid). Mole weight: 830.49 (free acid). | |
| M344 | M344 is a potent HDAC inhibitor, which can also induce expression of the pro-apoptotic genes, Puma and Bax, together with the morphological features of apoptosis, in MCF-7 cells. Alternative Names: M 344; M-344; Histone Deacetylase Inhibitor III. Grades: >98%. CAS No. 251456-60-7. Molecular formula: C16H25N3O3. Mole weight: 307.39. | |
| m7(3'OMeG)(5')ppp(5')(2'OMeG)pG | EZ Cap Reagent GG (3'OMe) is a co-transcription capping reagent. Alternative Names: EZ Cap Reagent GG (3' OMe) for co-transcriptional capping of mRNA; EZ Cap Reagent GG (3' OMe); GGG(3'OMe); m7(3'OMeG)ppp(2'OMeG)pG. Grades: ≥95% by AX-HPLC. CAS No. 2089461-54-9. Molecular formula: C33H45N15O25P4. Mole weight: 1175.69. | |
| m7G(5')ppp(5')(2'OMeA)pG | Used for in vitro transcription of 5'-capped mRNA to produce a Cap 1 structure. Compared with the Cap 0 structure, the mRNA with Cap 1 structure is more suitable for the mammalian system and has a higher transcription efficiency. Alternative Names: EZ Cap™ Reagent AG [m7G(5')ppp(5')(2'OMeA)pG]. Grades: ≥95% by AX-HPLC. Molecular formula: C32H43N15O24P4 (free acid). Mole weight: 1145.68 (free acid). | |
| m7G(5')ppp(5')(2'OMeA)pU | A 5'cap analog used for co-transcriptional capping of mRNA. The product is specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN). Alternative Names: Uridine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; (m7)Gppp(5')(m2'O)ApU; m7G(5')ppp(5')(2'-OMeA)pU; m7Gppp(5')A2'OMepU; m7GpppAmpU trinucleotide cap; GAU. Grades: ≥95% by HPLC. CAS No. 2734858-38-7. Molecular formula: C31H42N12O25P4. Mole weight: 1106.63. | |
| m7G(5')ppp(5')(2'OMe,m6A)pG | m7G(5')ppp(5')(2'OMe,m6A)pG is a trinucleotide mRNA 5' cap analogs. m7G(5')ppp(5')(2'OMe,m6A)pG can be used for RNA synthesis in vitro. Alternative Names: Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-N-methyl-2'-O-methylguanylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-N-methyl-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium, inner salt; CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG; GAG(m6A); m7Gppp(2'OMe,m6A)pG; m7Gpppm6AmpG. Grades: ≥98%. CAS No. 71340-22-2. Molecular formula: C33H45N15O24P4. Mole weight: 1159.69. | |
| m7GDP | m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism. Alternative Names: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP; 7-Methyl-Guanosine-5'-Diphosphate; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-; 7-Methylguanosine 5'-(trihydrogen diphosphate); 7-Methyl-GDP; 7-Methylguanosine 5'-diphosphate; 7-methylguanosine 5'-diphosphate(1+); N7-methylguanosine 5'-diphosphate. Grades: 95%. CAS No. 117723-13-4. Molecular formula: C11H18N5O11P2. Mole weight: 458.24. | |
| m7GMP | m7GMP, the eminent molecule widely employed in the biomedical sphere, holds paramount importance in the production of mRNA and viral RNA. Its indispensable contribution lies within the realm of cap-dependent translation initiation, where it assumes a distinctive stance as the prime target for recognition by the initiation factor eIF4E. Wholly engrossed in the intricate domains of RNA modification and processing, m7GMP exhibits vast prospects for the research of RNA-associated afflictions, including the notorious cancer and pernicious viral infections. Alternative Names: 7-methyl-guanosine-5'-monophosphate, triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 47442-17-1. Molecular formula: C11H16N5O8P (free acid). Mole weight: 377.25 (free acid). | |
| m7GP3G (Monomethylated Cap Analog) | m7GP3G (Monomethylated Cap Analog) is an indispensable compound extensively employed, supporting the synthesis of mRNAs possessing altered RNA cap structures. This remarkable compound assumes a pivotal function in advancing studies pertaining to gene expression and mRNA processing, particularly in the progressive frontiers of RNA vaccines and mRNA therapeutics. By enabling investigation into cap-dependent translation mechanisms, as well as facilitating the evaluation of mRNA stability and translational efficiency, this product fosters an unprecedented comprehension of intricate cellular processes. Alternative Names: Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7Gp3G; m7GpppG; mG(5')ppp(5')G; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate; mCAP; m7G(5')ppp(5')G Cap Analog; N7-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine; 7-Methyl-guanosine-5'-triphosphate-5'-guanosine; M7-GpppG. Grades: ≥95% by HPLC. CAS No. 62828-64-2. Molecular formula: C21H29N10O18P3. Mole weight: 802.43. | |
| m7GP3G (Monomethylated Cap Analog) sodium salt | m7GP3G (Monomethylated Cap Analog) sodium salt is a vital product in the biomedical industry used for studying mRNA capping and translation initiation. It serves as a crucial tool for investigating RNA transcription, translation processes and mRNA stability. By mimicking the natural RNA cap structure, m7GP3G sodium salt aids in understanding diseases like cancer and viral infections, ultimately enabling the development of effective researchs. Alternative Names: m7G(5')ppp(5')G Sodium salt; P1-(5'-7-methyl-guanosyl) P3-(5'-(guanosyl))triphosphate, sodium salt; M7-GpppG sodium salt; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt, sodium salt; m7Gp3G sodium salt; m7GpppG sodium salt; mCAP sodium salt. Grades: ≥95% by HPLC. Molecular formula: C21H29N10O18P3 (free acid). Mole weight: 802.43 (free acid). | |
| m7GpppAmpG | m7GpppAmpG is a trinucleotide 5' cap analog with the capping efficiencies for the obtained RNAs of 90%. It is used to transcribe 5'cap mRNA in vitro to produce the Cap 1 structure, which is more suitable for mammalian systems and has higher transcriptional efficiency than the Cap 0 structure. m7GpppAmpG Cap Analog is a co-transcriptional capping agent that transcribes 5' capped mRNA in vitro to form the Cap 1 structure. Alternative Names: m7G(5')ppp(5')(2'-OMeA)pG; GAG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7GpppA2'OmepG. Grades: ≥95% by HPLC. CAS No. 62858-30-4. Molecular formula: C32H43N15O24P4. Mole weight: 1145.67. | |
| m7GpppGmpG | m7GpppGmpG is a trinucleotide 5 cap analog with the capping efficiencies for the obtained RNAs of 86%. Alternative Names: EZ Cap Reagent GG; EZ Cap Reagent GG for co-transcriptional capping of mRNA; m7G(5')ppp(5')(2'OMeG)pG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methylguanylyl-(3'→5')-, inner salt; m7Gppp(2'OMeG)pG; CAP GGG m7G(5')ppp(5')(2'OMeG)pG; GGG. Grades: ≥98%. CAS No. 1258049-00-1. Molecular formula: C32H43N15O25P4. Mole weight: 1161.66. | |
| m7GpppUpG | m7GpppUpG, an oligonucleotide, is an M 7 GpppNpG trinucleotide cap analogue. m7GpppUpG can be used as a chemical tool enabling manufacturing of RNA featuring either cap 0 or cap 1 structures. CAS No. 2638447-85-3. Molecular formula: C30H40N12O26P4. Mole weight: 1108.6. | |
| Macitentan Impurity 1 | An impurity of Macitentan, a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension. Alternative Names: Despropylaminosulfonyl Macitentan; 5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinamine; ACT 080803. Grades: > 95%. CAS No. 1433875-21-8. Molecular formula: C16H13Br2N5O2. Mole weight: 467.11. | |
| MADUROSE | MADUROSE. CAS No. 4682-46-6. Molecular formula: C7H14O6. Mole weight: 194.18. | |
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