BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
Nicardipine Hydrochloride
Nicardipine is a calcium channel blocker used to treat high blood pressure and angina. Alternative Names: RS-69216; RS 69216; RS69216; YC-93; YC 93; YC93. Grades: >98% (HPLC). CAS No. 54527-84-3. Molecular formula: C26H29N3O6.HCl. Mole weight: 515.99.
Nicardipine Methyl Amino Derivative
An impurity of Nicardipine, which is a calcium channel blocker used to treat high blood pressure and angina. Alternative Names: 3-Methyl 5-(2-(methylamino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. Grades: > 95%. CAS No. 58368-87-9. Molecular formula: C19H23N3O6. Mole weight: 389.41.
Nicardipine Methyl Amino Derivative HCl salt
An impurity of Nicardipine, which is a calcium channel blocker used to treat high blood pressure and angina. Alternative Names: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[2-(methylamino)ethyl] ester, hydrochloride (1:1); 3-methyl 5-(2-(methylamino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride. Grades: 95%. CAS No. 93286-16-9. Molecular formula: C19H24ClN3O6. Mole weight: 425.87.
Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment. It can be used for tapeworm disease in livestock and poultry, and fasciasis in ruminants. Uses: Anticestodal agents; antinematodal agents; molluscacides. Alternative Names: Niclosamide, Clonitralide, Fenasal, BAY 2353, NSC 178296, WR 46234, BAY-2353, NSC-178296, WR-46234, BAY2353, NSC178296, WR46234. Grades: >98%. CAS No. 50-65-7. Molecular formula: C13H8Cl2N2O4. Mole weight: 327.12.
Niclosamide ethanolamine salt
Niclosamide is an oral antihelminthic drug, which has been used to treat tapeworm infection for about 50 years. Niclosamide is also used as a molluscicide for water treatment in schistosomiasis control programs. Recently, several groups have independently discovered that niclosamide is also active against cancer cells. Evidence supports that niclosamide targets multiple signaling pathways (NF-κB, Wnt/β-catenin, Notch, ROS, mTORC1, and Stat3), most of which are closely involved with cancer stem cells. Given its potential antitumor activity, clinical trials for niclosamide and its derivatives are warranted for cancer treatment. Alternative Names: BAY-73; BAY-6076; Bayluscide; HL 2448; Clonitralid; Niclosamide-olamine; Niclosamidel. Grades: ≥98%. CAS No. 1420-04-8. Molecular formula: C13H8Cl2N2O4·C2H7NO. Mole weight: 388.2.
Niclosamide monohydrate
Niclosamide Monohydrate is used for the treatment of most tapeworm infections by inhibiting DNA replication. It inhibits the TNF-induced NF-κB reporter activity in a dose- and time-dependent manner in U2OS cells. It also inhibits TNF-induced degradation of IκBα and relocation of p65 in a dose- and time-dependent manner in HL-60, Molm13, or AML primary cells. Alternative Names: Niclocide monohydrate; BAY2353 monohydrate; BAY 2353 monohydrate; BAY-2353 monohydrate; Cestocid monohydrate; Sagimid monohydrate; Yomesan monohydrate. Grades: >98%. CAS No. 73360-56-2. Molecular formula: C13H10Cl2N2O5. Mole weight: 345.13.
Nicotinamide adenine dinucleotide phosphate sodium salt hydrate
Nicotinamide adenine dinucleotide phosphate sodium salt hydrate. Alternative Names: Triphosphopyridine nucleotide sodium salt hydrate. CAS No. 698999-85-8. Molecular formula: C21H29N7NaO18P3. Mole weight: 765.39 (anhydrous basis).
Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt
Nicotinamide riboside is a form of pyridine nucleoside with a nicotinamide. It is a precursor to NAD+ and a source of vitamin B3. Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells. It also activates SIRT1 and SIRT3 in vitro. Alternative Names: Nicotinamide-beta-riboside; Nicotinamide ribonucleoside; N-Ribosylnicotinamide; 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium; Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-; 3-Pyridinecarboxamide, 1-β-D-ribosyl-; Nicotinamide ribose; Ribosylnicotinamide. Grades: ≥95% (Contain ~80% food grade dextrin as stabilizer). CAS No. 1341-23-7. Molecular formula: C11H15N2O5. Mole weight: 255.25.
Nicotinamide Riboside Triflate (α/β mixture)
Nicotinamide analog, Nicotinamide riboside (β-NAR) is an intermediate in one biosynthetic pathway by which Nicotamide is converted into NAD (Nicotinamide Adenine Dinucleotide). Uses: Nicotinamide analog. nicotinamide riboside (β-nar) is an intermediate in one biosynthetic pathway by which nicotamide is converted into nad (nicotinamide adenine dinucleotide) cas 1341-23-7 for free base form. Alternative Names: 3-(Aminocarbonyl)-1-D-ribofuranosylpyridinium Trifluoromethanesulfonic Acid Salt;Nicotinamide Ribose Triflate; Nicotinamide Ribonucleoside Triflate; NAR; Ribosylnicotinamide Triflate. Grades: 97%. CAS No. 445489-49-6. Molecular formula: C12H15F3N2O8S. Mole weight: 404.32.
Nicotine-d4
Labelled rac-Nicotine. A metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Alternative Names: 3-(1-Methyl-2-pyrrolidinyl)pyridine-2,4,5,6-d4; (±)-Nicotine-d4; (±)-3-(1-Methyl-2-pyrrolidinyl)pyridine-d4; (R,S)-Nicotine-d4; (±)-Nicotine-d4; 1-Methyl-2-(3-pyridyl)pyrrolidine-d4; DL-Nicotine-d4. Grades: > 95%. CAS No. 350818-69-8. Molecular formula: C10H10N2D4. Mole weight: 166.26.
Nicotinic Acid Adenine Dinucleotide
Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide; a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. Alternative Names: Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-carboxy-1-β-D-ribofuranosylpyridinium, inner salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-pyrophosphate, inner salt; Pyridinium, 3-carboxy-1-β-D-ribofuranosyl-, hydroxide, 5'→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt; 1: PN: WO2006081329 PAGE: 47 claimed sequence; Adenine-nicotinic Acid Dinucleotide; Codehydrogenase I, carboxy deamido analog; Codehydrogenase I, nicotinic acid analog; Deamido-NAD; Deamidodiphosphopyridine Nucleotide; Desamido NAD; Nicotinate Adenine Dinucleotide; Nicotinic Acid-adenine Dinucleotide. CAS No. 6450-77-7. Molecular formula: C21H26N6O15P2. Mole weight: 664.41.
Nicotinic acid adenine dinucleotide sodium
A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Alternative Names: sodium [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl] [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate. Grades: > 95%. CAS No. 104809-30-5. Molecular formula: C21H25N6O15P2. Na. Mole weight: 663.41 22.99.
Nicotinic Acid Riboside
An effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells. Alternative Names: 3-Carboxy-1-β-D-ribofuranosylpyridinium Inner Salt; 3-Carboxy-1-β-D-ribofuranosyl-pyridinium Hydroxide Inner Salt; Nicotinic Acid Ribonucleoside; Nicotinic Riboside. Grades: 95%. CAS No. 17720-18-2. Molecular formula: C11H13NO6. Mole weight: 255.22.
Nifedipine EP Impurity D
Nifedipine EP Impurity D is an impurity of Nifedipine, which is a calcium channel blocker used to treat angina, high blood pressure, Raynaud's phenomenon, and premature labor. Alternative Names: Methyl 3-aminocrotonate; 2-Butenoic acid, 3-amino-, methyl ester; Crotonic acid, 3-amino-, methyl ester; Methyl 3-amino-2-butenoate; 3-Aminobut-2-enoic acid methyl ester; 3-Aminocrotonic acid methyl ester; Methyl 3-amino-2-butenenoate; Methyl 3-aminocrotonoate; Methyl β-aminocrotonate; β-Aminocrotonic acid methyl ester. Grades: ≥95%. CAS No. 14205-39-1. Molecular formula: C5H9NO2. Mole weight: 115.13.
Nifurpirinol
Nifurpirinol is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. It is a more potent prodrug compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models. Alternative Names: Furpyrinol; Furanace; 2-Pyridinemethanol, 6-(2-(5-nitro-2-furanyl)ethenyl)-; P-7138. Grades: 98%. CAS No. 13411-16-0. Molecular formula: C12H10N2O4. Mole weight: 246.22.
Nifurprazine
Nifurprazine residues in body fluids and tissues of cattle following intrycysternal administration. Alternative Names: (E)-6-(3-(5-Nitro-2-furyl)vinyl)-3-pyridazinylamin; 3-Amino-6-((5-nitro-2-furil)-vinil)-1,2-diazina; 3-Amino-6-((5-nitro-2-furil)-vinil)-1,2-diazina [Italian]; 3-Amino-6-(2-(5-nitro-2-furyl)vinyl)pyradizine; 3-Amino-6-(2-(5-nitro-2-furyl)vinyl)pyridazine. Grades: > 95%. CAS No. 1614-20-6. Molecular formula: C10H8N4O3. Mole weight: 232.2.
Nigeran
Nigeran is a type of polysaccharide primarily found in certain fungi, particularly in Aspergillus niger and other related species. Nigeran is a β-glucan polysaccharide with a distinct structure featuring β-1,3 and β-1,6 glycosidic bonds. It is soluble in water and can act as a thickening agent in various applications. Its unique properties and potential biological activities make it of interest in food, pharmaceutical, and biotechnological applications. Alternative Names: Mycodextran. CAS No. 31799-84-5.
Nigerose
Nigerose is an influential polysaccharide compound extensively applied in the research of metabolic anomalies, particularly diabetes. Alternative Names: 3-O-a-D-Glucopyranosyl-D-glucose; Sakebiose; 3-O-α-D-Glucopyranosyl-D-glucose; Glc(a1-3)aldehydo-Glc; (2R,3S,4R,5R)-2,4,5,6-Tetrahydroxy-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal. CAS No. 497-48-3. Molecular formula: C12H22O11. Mole weight: 342.30.
Nile Blue A perchlorate
Nile Blue A perchlorate is a laser dye used for pulsed and CW operations. Alternative Names: Nile Blue 690 Perchlorate; 5-amino-9-(diethylamino)-benzo[a]phenoxazin-7-ium perchlorate; Nileblau. CAS No. 53340-16-2. Molecular formula: C20H20N3O?ClO4. Mole weight: 417.84.
Nile Red
Nile Red is an aphotostable and lipophilic stain for intracellular lipids and hydrophobic domains of proteins and also for staining of lysosomal phospholipid inclusions. Uses: Used as a polarity-sensitive fluorescent probe of lipids and proteins. Alternative Names: Nile Blue A Oxazone. Grades: 95%. CAS No. 7385-67-3. Molecular formula: C20H18N2O2. Mole weight: 318.37.
Nilotinib
Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. It is under investigation as a possible treatment for chronic myelogenous leukemia (CML). Alternative Names: Tasigna; AMN107; AMN 107; AMN-107; BW 33A, 51W89. Grades: ≥98%. CAS No. 641571-10-0. Molecular formula: C28H22F3N7O. Mole weight: 529.52.
Nilotinib hydrochloride
Nilotinib is an orally bioavailable Bcr-Abl tyrosine kinase inhibitor displaying antineoplastic activity. It is promisingly used for the treatment of chronic myelogenous leukemia (CML). Uses: Tyrosine kinase inhibitors. Alternative Names: AMN-107 HCl; 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide hydrochloride. CAS No. 923288-95-3. Molecular formula: C28H22F3N7O·HCl. Mole weight: 565.98.
Nilotinib monohydrochloride monohydrate
Nilotinib monohydrochloride monohydrate is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. It binds to and stabilizes the inactive conformation of the kinase domain of the Abl protein of the Bcr-Abl fusion protein, resulting in the inhibition of the Bcr-Abl-mediated proliferation of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) cells. It also inhibits the receptor tyrosine kinases platelet-derived growth factor receptor (PDGF-R) and c-kit, a receptor tyrosine kinase mutated and constitutively activated in most gastrointestinal stromal tumors (GISTs). Uses: Tyrosine kinase inhibitors. Alternative Names: AMN-107; AMN 107; AMN107; Tasigna. Grades: >98%. CAS No. 923288-90-8. Molecular formula: C28H25ClF3N7O2. Mole weight: 583.99.
NIM811
NIM811 is a dual inhibitor of mitochondrial permeability transition and cyclophilin. It exhibits potent in vitro inhibitory activity against hepatitis C virus (HCV). Alternative Names: (Melle-4)cyclosporin; Sdz-nim-811; NIM-811; NIM 811. Grades: 98.82%. CAS No. 143205-42-9. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Nimesulide
Nimesulide is a selective COX-2 inhibitor. Alternative Names: N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide. Grades: > 95%. CAS No. 51803-78-2. Molecular formula: C13H12N2O5S. Mole weight: 308.3.
Nintedanib Acetyl Impurity
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Alternative Names: (3Z)-1H-Indole-6-carboxylic acid, 3-[[[4-(acetylmethylamino)phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-, methyl ester. Grades: ≥95%. CAS No. 1139458-48-2. Molecular formula: C26H23N3O4. Mole weight: 441.48.
Nintedanib esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β. Uses: The treatment of idiopathic pulmonary fibrosis. Alternative Names: Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino) (phenyl)methylidene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylate ethanesulfonate; BIBF1120; BIBF 1120 BIBF-1120; Nintedanib esylate Nintedanib ethanesulfonate salt; Intedanib; Brand name OFEV Vargatef. Grades: >98%. CAS No. 656247-18-6. Molecular formula: C33H39N5O7S. Mole weight: 649.76.
Nintedanib Impurity 6 (Intedanib Impurity 6)
BIBF 1202 is the major in-vivo metabolite of BIBF 1120, which is an oral triple angiokinase inhibitor targeting VEGFR, PDGFR, FGFR. It is a related compound of Intedanib, which is an indolinone derivative that inhibits angiokinase and an antitumor agent. It is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (VEGF) signaling pathway thus inhibition of tumor angiogenesis. Uses: Bibf 1202 is a novel treatment modality in oncology through blockade of the vascular endothelial growth factor (vegf) signaling pathway thus inhibition of tumor angiogenesis. Alternative Names: BIBF-1202; BIBF 1202; BIBF1202. (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid;(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid;Nintedanib Impurity 5. Grades: >98%. CAS No. 894783-71-2. Molecular formula: C30H31N5O4. Mole weight: 525.60.
Nintedanib Impurity D
An impurity of Nintedanib, a receptor tyrosine kinase (RTK) inhibitor that binds to vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Nintedanib is used as a medication for the treatment of idiopathic pulmonary fibrosis. Alternative Names: (3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester. Grades: >95%. CAS No. 1987887-92-2. Molecular formula: C24H21N3O3. Mole weight: 399.45.
Niperotidine
Niperotidine is a histamine H2 receptor antagonist used in the treatment of intestinal disorders. Alternative Names: Piperonyl ranitidine; N-(1,3-Benzodioxol-5-ylmethyl)-N'-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitro-1,1-ethenediamine; 1,1-Ethenediamine, N-(1,3-benzodioxol-5-ylmethyl)-N'-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-2-nitro-; N-(2-((5-((Dimethylamino)methyl)furfuryl)thio)ethyl)-2-nitro-N'-piperonyl-1,1-ethenediamine. Grades: ≥95%. CAS No. 84845-75-0. Molecular formula: C20H26N4O5S. Mole weight: 434.51.
Nipocalimab
Nipocalimab is a humanized monoclonal antibody targeting the neonatal Fc receptor (FcRn). Nipocalimab has been investigated for the treatment of myasthenia gravis (MG). Alternative Names: M281. CAS No. 2211985-36-1.
Niraparib
Niraparib is an inhibitor of PARP, which was approved by FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy. Alternative Names: MK-4827; MK 4827; MK4827; (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; ZEJULA; 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide. CAS No. 1038915-60-4. Molecular formula: C19H20N4O. Mole weight: 320.396.
N-Isobutyrylguanosine
N-Isobutyrylguanosine is used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis. Alternative Names: N2-iso-Butyrylguanosine; N2-Isobutyrylguanosine; N-(2-methylpropanoyl)guanosine; N-(2-Methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-methylpropanamide; ribo Guanosine (n-ibu). Grades: ≥95%. CAS No. 64350-24-9. Molecular formula: C14H19N5O6. Mole weight: 353.33.
N-Isopentenyladenine
N-Isopentenyladenine is a versatile compound, garnering recognition due to its multifaceted pharmaceutical applications. Its predominant utilization lies in the realm of plant tissue culture, where it functions as a phenomenal cytokinin hormone, effectively stimulating growth and orchestrating plant development. Alternative Names: N6-(2-Isopentenyl)adenine; 6-(3,3-Dimethylallylamino)purine; N-(3-Methyl-2-buten-1-yl)-9H-purin-6-amine; 6-(3-Methyl-2-buten-1-ylamino)purine; 6-(Δ2-Isopentenylamino)purine; 6-(γ,γ-Dimethylallylamino)purine; 6-Isopentenyladenine; 6-N-(3-Methylbut-2-enylamino)purine; 6-[(3-Methyl-2-butenyl)amino]purine; Bryokinin; DMAA; Enadenine; IPA; Isopentenyladenine; N-(3-Methyl-2-butenyl)-1H-purin-6-amine; N-(γ,γ-Dimethylallyl)adenine; N6-(3-Methyl-2-butenyl)adenine; N6-(Δ2-Isopentenyl)adenine; N6-(Δ2-Isopentenyl)aminopurine; N6-(γ,γ-Dimethylallyl)aminopurine; N6-Isopentenyladenine; NSC 106958. Grades: 98%. CAS No. 2365-40-4. Molecular formula: C10H13N5. Mole weight: 203.25.
N-(Iso-pentyl)acetamide
N-(Iso-pentyl)acetamide. Alternative Names: N-(Iso-pentyl)acetamide; N-(3-Methylbutyl)acetamide. Grades: 95%. CAS No. 13434-12-3. Molecular formula: C7H15NO. Mole weight: 129.20.
N-Isopropylbenzylamine
N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it's similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA. Alternative Names: N-benzylpropan-2-amine. Grades: 97 %. CAS No. 102-97-6. Molecular formula: C10H15N. Mole weight: 149.23.
N-isopropylmaleimide
N-isopropylmaleimide. Alternative Names: N-isopropylmaleimide. Grades: 98%. CAS No. 1073-93-4. Molecular formula: C7H9NO2. Mole weight: 139.15.
N-Isopropyl Noratropine
An impurity of Ipratropium Bromide, which is a muscarinic antagonist and a bronchodilator. Uses: Noratropine derivative, an intermediate in the production of ipratropium. Alternative Names: endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate; N-Isopropylnoratropine; rac-(R*)-α-(Hydroxymethyl)benzeneacetic acid (1R,5S)-8-isopropyl-8-azabicyclo[3.2.1]octane-3α-yl ester; N-Desmethyl Ipratropium; α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8-(1-methylethyl)-8-azabicyclo[3.2.1]-oct-3-yl ester; Ipratropium Bromide Impurity 13; Ipratropium EP Impurity E; Ipratropium Impurity E; 1αH,5αH-Nortropan-3α-ol, 8-isopropyl-, (±)-tropate (ester); Benzeneacetic acid, α-(hydroxymethyl)-, 8-(1-methylethyl)-8-azabicyclo[3.2.1]oct-3-yl ester, endo-(±)-; Tropic acid, 8-isopropyl-3α-nortropanyl ester. Grades: ≥95%. CAS No. 22235-81-0. Molecular formula: C19H27NO3. Mole weight: 317.42.
N-ISOVALEROYLGLYCINE
N-ISOVALEROYLGLYCINE. CAS No. 16284-60-9. Molecular formula: C7H13NO3. Mole weight: 159.18.
NITD-688
NITD-688 is an orally active panserotype inhibitor of dengue virus NS4B protein that can be used in dengue virus (DENV) studies. Alternative Names: NITD-688;2407227-31-8;M8MU6T45GY;UNII-M8MU6T45GY;Benzeneacetamide, 4-(aminosulfonyl)-N-(3-cyano-5-(cyclohexylmethyl)-4,5,6,7-tetrahydro-6,6-dimethylthieno(3,2-C)pyridin-2-yl)-;SCHEMBL21598864;MS-29302;HY-138543;CS-0149167;N-(3-Cyano-5-(cyclohexylmethyl)-6,6-dimethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-2-(4-sulfamoylphenyl)acetamide. Grades: ≥95%. CAS No. 2407227-31-8. Molecular formula: C41H86NO5P. Mole weight: 704.1.
Nitrate Reductase (NAD[P]H) from Aspergillus niger
Nitrate Reductase (NAD[P]H) from Aspergillus niger. Alternative Names: NAD(P)H:Nitrate oxidoreductase. CAS No. 9029-27-0. Molecular formula: Pt27. Mole weight: 5267.00.
Nitrilotriacetic acid
Nitrilotriacetic acid (CAS# 139-13-9) is a chelating agent which forms coordination compounds with metal ions. Nitrilotriacetic acid is used in complexometric titrations and as well as for protein isolation and purification in the His-tag method. This compound is a contaminant of emerging concern (CECs). Alternative Names: 2-[bis(carboxymethyl)amino]acetic acid. CAS No. 139-13-9. Molecular formula: C6H9NO6. Mole weight: 191.14.
Nitrilotriacetic acid trisodium salt monohydrate
Nitrilotriacetic acid trisodium salt monohydrate (CAS# 18662-53-8 ) is a useful research chemical. Alternative Names: trisodium;2-[bis(carboxylatomethyl)amino]acetate;hydrate. Grades: 98 %. CAS No. 18662-53-8. Molecular formula: C6H8NNa3O7. Mole weight: 275.10.
ATMP is used in circulating cooling water of thermal power plants and oil refineries, also in oil field water injection system, to play a role in reducing the corrosion and scaling of metal equipment or piping. ATMP is used as metal ion chelating agent or metal surface treatment agent in the textile printing and dyeing industry. Uses: Atmp is usually used together with organophosphoric acid, polycarboxylic acid and salt to built all organic alkaline water treatment agent. atmp can be used in many different circulating cool water system. the dosage of 1-20 mg/l is recommended. as corrosion inhibitor, the dosage of 20-60 mg/l is preferred. Alternative Names: ATMP; ATMPA; Dequest 2000; BRIQUEST 301-50A; TRIS(PHOSPHONOMETHYL)AMINE; NITRILOTRIMETHANEPHOSPHONIC ACID; Aminotrimethylene Phoshonic Acid. Grades: 95 %. CAS No. 6419-19-8. Molecular formula: N(CH2PO3H2)3. Mole weight: 299.05.
NITROBENZENE (13C6)
NITROBENZENE (13C6). Alternative Names: NITROBENZENE (13C6); NITROBENZENE-13C6, 99 ATOM % 13C. CAS No. 89059-37-0. Molecular formula: C6H5NO2. Mole weight: 129.16.
Nitrofurantoin related compound A
Nitrofurantoin related compound A is a new derivative of 5-Nitro-2-furfural. It is proved to be bactericidal. Alternative Names: 3-(5-Nitrofurfurylideneamino)hydantoic acid; N-(Aminocarbonyl)-N-{[(5-nitro-2-furanyl)methylene]amino}glycine; 2-[1-Carbamoyl-2-(5-nitrofurfurylidene)hydrazino]acetic acid; 2-[1-(Aminocarbonyl)-2-[(5-nitro-2-furanyl)methylene]hydrazinyl]acetic Acid; [(Aminoca. Grades: > 95%. CAS No. 63981-22-6. Molecular formula: C8H8N4O6. Mole weight: 256.17.
Nitroprusside disodium dihydrate is a nitric oxide donor / releaser and potent vasodilator. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model. Alternative Names: Sodium nitroferricyanide(III) dihydrate; Sodium pentacyanonitrosylferrate(III) dihydrate; Sodium nitroprusside dihydrate. Grades: 99%. CAS No. 13755-38-9. Molecular formula: C5H4FeN6Na2O3. Mole weight: 297.95.
Nitrosobiotin
Nitrosobiotin is a N-nitrosamine derivative of biotin. Nitrosobiotin has high affinity for avidin and streptavidin, making it an ideal tool for affinity labeling experiments. Alternative Names: 1'-Nitrosobiotin. CAS No. 56859-26-8. Molecular formula: C10H15N3O4S. Mole weight: 273.31.
Nitrosoiminodiacetic acid
Nitrosoiminodiacetic acid is a nitrosated analog of iminodiacetic acid. Alternative Names: N-Nitrosoiminodiacetic acid; N-(Carboxymethyl)-N-nitrosoglycine. CAS No. 25081-31-6. Molecular formula: C4H6N2O5. Mole weight: 162.10.
Nitroterephthalic acid
Nitroterephthalic acid (CAS# 610-29-7) is a useful research chemical. Alternative Names: 2-nitroterephthalic acid. CAS No. 610-29-7. Molecular formula: C8H5NO6. Mole weight: 211.13.
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Alternative Names: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84.
NKH 477
NKH477 is a water-soluble analog of forskolin, which is an adenylyl cyclase activator, but it is sparingly soluble in aqueous solutions. It has both inotropic and vasodilator effects. Uses: Vasodilator agents. Alternative Names: NKH 477; NKH477; NKH-477; N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 138605-00-2. Molecular formula: C27H43NO8.HCl. Mole weight: 546.1.
N-Lauroylglutamic acid
N-Lauroylglutamic acid is a natural amino acid surfactant and anionic detergent that can increase the solubility of long-chain alkyl gallates. Alternative Names: L-Glutamic acid, N-(1-oxododecyl)-; Glutamic acid, N-lauroyl-; Glutamic acid, N-lauroyl-, L-; N-(1-Oxododecyl)-L-glutamic acid; Amisoft LA; Lauroylglutamic acid; N-Dodecanoyl-L-glutamic acid; N-Lauroyl-L-glutamic acid; NSC 522180. Grades: 95%. CAS No. 3397-65-7. Molecular formula: C17H31NO5. Mole weight: 329.43.
N-Lauroylsarcosine sodium salt
Sodium lauroyl sarcosinate (INCI), also known as sarkosyl, is an ionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. In molecular biology experiments, sarkosyl is used to inhibit the initiation of DNA transcription.This surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate. Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH. The carboxylate has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.pH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.Addition of an mixture of equal parts of sodium lauroyl sarcosinate and the non-ionic surfactant sorbitan monolaurate (S20) to water led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone. Such aggregates can help carry other small molecules, such as drugs, through the skin. Uses: Used as a detergent, foaming agent, and antienzyme for dentifrices; permitted for use as an inert ingredient in non-food pesticide products; sodium lauroyl sarcosinate (inci), also known as sarkosyl, is an ionic surfactant derived from sarcosine, used as a foaming and cleansing
NLG-919
NLG919 is an orally available inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), a cytosolic enzyme responsible for the oxidation of the essential amino acid tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, this agent increases tryptophan levels, restores the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, T-lymphocytes, and causes a reduction in tumor-associated regulatory T-cells (Tregs). Alternative Names: GDC0919; GDC-0919; GDC 0919; NLG919; NLG 919; NLG-919; RG6078; RG-6078; RG 6078. Grades: > 98%. CAS No. 1402836-58-1. Molecular formula: C18H22N2O. Mole weight: 282.38.
N-Linoleoyl-DPPE
N-linoleoyl-DPPE is a specific non-endocannabinoid type of N-acylphosphatidylethanolamines (NAPEs) which are important intermediates in the endocannabinoid biosynthesis pathway, producing anandamide through hydrolysis by NAPE-specific phospholiase D. Alternative Names: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-linoleoyl; 16:0 PE-N 18:2. CAS No. 2148334-94-3. Molecular formula: C55H107N2O9P. Mole weight: 971.44.
N-Methoxy-2,N-dimethylacrylamide. Alternative Names: N-Methoxy-2,N-dimethylacrylamide; N-Methoxy-N,2-dimethyl-2-propenamide. Grades: 95%. CAS No. 132960-14-6. Molecular formula: C6H11NO2.
N-Methyl-2-pyridone-5-carboxamide-d6
An isotope labelled metabolite of Niacin. Niacin also known as nicotinic acid, is an organic compound and is, depending on the definition used, one of the 20 to 80 essential human nutrients. Grades: 95% by HPLC; 98% atom D. Molecular formula: C7H2D6N2O2. Mole weight: 158.19.
N-Methyl-3-phenyl-2-propen-1-amine
N-Methyl-3-phenyl-2-propen-1-amine (CAS# 83554-67-0) is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamine oxidase. Alternative Names: (E)-N-methyl-3-phenylprop-2-en-1-amine. Grades: 95 %. CAS No. 83554-67-0. Molecular formula: C10H13N. Mole weight: 147.22.
N-methyl-5,6-dihydroxyindole
An impurity of Epinephrine. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Alternative Names: 1-Methyl-1H-indole-5,6-diol; Epinephrine Impurity 8. CAS No. 4821-00-5. Molecular formula: C9H9NO2. Mole weight: 163.17.