BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Paritaprevir | Paritaprevir could inhibit viral phosphoprotein NS5A and is significant to viral replication and other activities. It also has been found to have potential effect agains hepatitis C virus. Alternative Names: ATB450; ABT-450; ABT 450; Paritaprevir; Veruprevir; Brand name: VIEKIRA PAK. Grades: 99.89%. CAS No. 1216941-48-8. Molecular formula: C40H43N7O7S. Mole weight: 765.886. |  |
| Parnate | In combination with CHIR99021, allows keratinocyte reprogramming with OK only. Uses: Reprogramming. Grades: 0.98. CAS No. 13492-01-8. | |
| Paromamine | Paromamine is an antibiotic that belongs to the aminoglycoside class. It is primarily used for its antimicrobial properties, targeting a wide range of bacterial infections. By interfering with bacterial protein synthesis, paromamine can effectively inhibit the growth and reproduction of susceptible pathogens. It is particularly effective against certain Gram-negative bacteria, making it a valuable tool in treating infections caused by these microorganisms. Additionally, paromamine has been used in veterinary medicine to manage bacterial infections in animals. Its ability to disrupt bacterial processes makes it an important component in the arsenal of antimicrobial agents. Alternative Names: Neomycin Sulfate EP Impurity D; Neomycin Impurity D; Framycetin Sulfate EP Impurity D; Neomycin B sulfate EP Impurity D; Neomycin D; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine; 4-O-α-D-Glucosaminyl-2-deoxystreptamine; Gentamine A; 2-Deoxy-D-streptamine-4-O-2-amino-2-deoxy-α-D-glucopyranoside. Grades: >95%. CAS No. 534-47-4. Molecular formula: C12H25N3O7. Mole weight: 323.34. | |
| Paromamine trihydrochloride | Paromamine trihydrochloride is a robust antibiotic product employed for the research purpose of bacterial infections, exerting its antimicrobial prowess by impeding the synthesis of bacterial proteins through its affinitive binding to the ribosome. This compound is used to study a myriad of pathogens encompassing both Gram-positive and Gram-negative bacterial strains. Alternative Names: Streptamine, 4-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-, hydrochloride (1:3); Paromamine, trihydrochloride; Streptamine, 4-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-, trihydrochloride; Paromamine, hydrochloride; 4-O-(2-Amino-2-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine trihydrochloride; 4-O-α-D-Glucosaminyl-2-deoxystreptamine trihydrochloride; Gentamine A trihydrochloride; Neomycin D trihydrochloride. CAS No. 18685-97-7. Molecular formula: C12H25N3O7.3HCl. Mole weight: 432.72. | |
| Paroxetine | Paroxetine is an antidepressant in the class of selective serotonin reuptake inhibitors (SSRIs). Uses: Antidepressive agents, second-generation; serotonin uptake inhibitors. Alternative Names: Paxil; Frosinor. Grades: 95%. CAS No. 61869-08-7. Molecular formula: C19H20FNO3. Mole weight: 329.37. | |
| Paroxetine maleate | Paroxetine maleate is a highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki = 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Alternative Names: (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine maleate; BRL-29060; FG-7051; BRL 29060; FG 7051; BRL29060; FG7051. Grades: ≥99% by HPLC. CAS No. 64006-44-6. Molecular formula: C19H20FNO3.C4H4O4. Mole weight: 445.44. | |
| Paroxetine Mesylate | An impurity of Paroxetine which is a selective serotonin reuptake inhibitor. Alternative Names: Paroxetine Mesylate; 217797-14-3; Paroxetine Mesilate; POT.mes; Paroxetine methanesulfonate; Brisdelle; Mesafem; Pexeva; Paroxetine methanesulphonate; LDMP; PO-T.MES; M711N184JE; (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine methanesulfonate; Paroxetine Mesylate [USAN]; UNII-M711N184JE; Paroxetine mesylate (USAN);(-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine Mesylate; (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidinemethanesulfonate; (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium; methanesulfonate; Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-,(3S,4R)-, Methanesulfonate. Grades: > 95%. CAS No. 217797-14-3. Molecular formula: C19H20FNO3.CH4O3S. Mole weight: 425.48. | |
| Parthenosin | Parthenosin is a natural compound which can be used in content analysis, pharmacological experiments, activity screening, etc. Grades: 98%. CAS No. 166196-16-3. Molecular formula: C25H26O13. Mole weight: 534.47. | |
| Patchouli oil | Patchouli is located in large areas of Asia (India, Sri Lanka, Taiwan, South China). The organic patchouli oil is obtained by water steam distillation of the fresh leaves of the patchouli scrub (Pogostemon cablin).The patchouli oil is a viscous, light to dark yellow, sometimes even brown colored, liquid. It has a characteristic woody-balsamic fragrance with slightly camphor notes. In cosmetic production, patchouli oil is used as a fresh component and fixative for men perfumes, oriental fragrances, wood and rose notes. It is also widely used for scenting soaps and cosmetics. Uses: Compresses; perfume; soap; bath additive. Alternative Names: Oils, patchouli; Oil of Patchouli. CAS No. 8014-9-3. | |
| Patent Blue V calcium salt | Patent Blue V calcium salt is a water-soluble food colouring. Alternative Names: Carmine Blue V; Acidal Carmine V; Merantine Blue V; Solar Pure Blue VX; Mitsui Acid Pure Blue VX; Dai-ei Acid Pure Blue VX; New Patent Blue A-CE Extra; New Patent Blue Extra Pure A; NSC 5010; Ethanaminium, N-(4-((4-(diethylamino)phenyl)(5-hydroxy-2,4-disulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-ethyl-, hydroxide, inner salt, calcium salt (2:1); Acid Blue 3 calcium salt; Food Blue 5; Patent Blue V hemicalcium salt; Acid Blue V calcium salt. Grades: 95%. CAS No. 3536-49-0. Molecular formula: C54H62CaN4O14S4. Mole weight: 1159.43. | |
| Patent blue V sodium salt | Patent blue V sodium salt is a pH dependent dye. This water-soluble dye is widely used in histology, immunohistochemistry, and tissue culture. Alternative Names: Patent Blue V sodium; C.I. Acid Blue 3; Acid blue 3 sodium salt; Hydrogen 4-4-(diethylamino)-5'-hydroxy-2',4'-disulphonatobenzhydrylidenecyclohexa-2,5-dien-1-ylidenediethylammonium (sodium salt). Grades: 85%. CAS No. 20262-76-4. Molecular formula: C27H31N2NaO7S2. Mole weight: 582.66. | |
| Patisiran Sodium | Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis. Alternative Names: RNA, (A-U-G-G-A-A-Um-A-C-U-C-U-U-G-G-U-Um-A-C-dT-dT), complex with RNA (G-Um-A-A-Cm-Cm-A-A-G-A-G-Um-A-Um-Um-Cm-Cm-A-Um-dT-dT), sodium salt (1:1:40); Onpattro; siRNA ALN-18328. Grades: 95% by SEC-HPLC. CAS No. 1386913-72-9. Mole weight: 13427.10 (AS: 6661.3; SS: 6765.8). | |
| Pazopanib HCl | Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. Alternative Names: TMC-114, UIC 94017. Grades: >98%. CAS No. 635702-64-6. Molecular formula: C21H23N7O2·HCl. Mole weight: 473.98. | |
| Pazopanib Impurity 1 | An impurity of Pazopanib which is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms. Grades: > 95%. CAS No. 1313372-75-6. Molecular formula: C8H7N3O2. Mole weight: 177.16. | |
| Pazopanib Impurity 3 | An impurity of Pazopanib which is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms. Grades: > 95%. CAS No. 221681-95-1. Molecular formula: C10H13N2. Mole weight: 161.23. | |
| PBAN-560 (degassed) | PBAN-560 (degassed). CAS No. 25265-19-4. Molecular formula: C10H13NO2. Mole weight: 179.22. | |
| p-Carborane | p-Carborane. Grades: 99%+. CAS No. 20644-12-6. Molecular formula: C2H12B10. Mole weight: 144.22. | |
| PCC0208017 | PCC0208017 is a novel inhibitor of MARK3/MARK4, suppressing glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability. Alternative Names: 2,4-Pyrimidinediamine, N4-(1H-pyrazol-3-ylmethyl)-N2-(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)-5-(trifluoromethyl)-; N4-(1H-Pyrazol-3-ylmethyl)-N2-(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)-5-(trifluoromethyl)-2,4-pyrimidinediamine; N4-((1H-Pyrazol-3-yl)methyl)-N2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-5-(trifluoromethyl)pyrimidine-2,4-diamine. Grades: ≥95%. CAS No. 2623158-64-3. Molecular formula: C19H20F3N7. Mole weight: 403.41. | |
| p-Chlorostyrene | 4-Chlorostyrene was used in the following studies: Study of chemical and biochemical properties of the vinyl group of styrene by the development of structure activity relationships (SAR).; Preparation of new bis(pyrazolyl)borato olefin complexes of copper(I). To investigate the regioselectivity in the cationic Heck reaction of 4-substituted styrenes. Uses: Used to make polychlorostyrene. Alternative Names: 4-Chlorostyrene; 1073-67-2; P-CHLOROSTYRENE; 1-Chloro-4-vinylbenzene; Styrene,p-chloro-; Parachlorostyrene. Grades: 95%. CAS No. 1073-67-2. Molecular formula: C8H7Cl. Mole weight: 138.59418. | |
| pCp-Azide | pCp-Azide, an indispensable biochemical reagent renowned for its critical role in facilitating the synthesis of fluorescent probes, is wielded by scientists to map intricate cellular structures. This reagent, a versatile and effective tool, stains proteins, nucleic acids, and carbohydrates to enable their identification and detection. Its unparalleled efficacy and safety have made it a staple in the biomedical industry, underpinning countless diagnostic and therapeutic applications in fields as diverse as oncology and infectious diseases. Alternative Names: Cytidine-5'-phosphate-3'-(15-azido-4,7,10,13-tetraoxa-pentadecanoyl-6-aminohexyl)phosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C26H47N7O16P2(free acid). Mole weight: 775.64 (free acid). | |
| pCp-Biotin | pCp-Biotin is a nucleoside phosphate activator with antiviral effects. It is also an effective anticancer agent. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt; Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Biotin, Triethylammonium salt. Grades: ≥95% by HPLC. Molecular formula: C25H42N6O13P2S1(free acid). Mole weight: 728.65 (free acid). | |
| pCp-Cy3 | pCp-Cy3 is a fluorescent dye commonly used in biomedical research, a derivative of Cyanine 3 (Cy3), which emits a red-orange fluorescence when excited by a particular wavelength of light. pCp-Cy3 is utilized for labeling biomolecules such as antibodies and nucleic acids, enabling their visualization and tracking in various biological assays and imaging techniques. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C46H64N6O18P2S2(free acid). Mole weight: 1115.11 (free acid). | |
| pCp-Cy5 | pCp-Cy5 is a fluorescent dye used in the realms of cell imaging, flow cytometry and fluorescence microscopy for studying mysteries of cancer and infectious diseases. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C48H66N6O18P2S2(free acid). Mole weight: 1141.14 (free acid). | |
| pCp-Desthiobiotin | pCp-Desthiobiotin, a chemical compound commonly applied in biomedicine, serves as an efficient isolation technique for proteins through affinity purification. It's often employed in tandem with streptavidin to capture and purify biotinylated proteins, thus proving instrumental in research on chronic conditions such as cancer and Alzheimer's. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-Desthiobiotin. Grades: ≥ 95 % by HPLC. Molecular formula: C24H42N6O13P2(free acid). Mole weight: 684.57 (free acid). | |
| p-Cresyl isobutyrate | p-Cresyl isobutyrate. Alternative Names: Propanoic acid, 2-methyl-, 4-methylphenyl ester; 4-Methylphenyl 2-methylpropanoate; Isobutyric acid, p-tolyl ester; 2-Methylpropanoic acid 4-methylphenyl ester; p-Methylphenyl isobutyrate; p-Tolyl isobutyrate. CAS No. 103-93-5. Molecular formula: C11H14O2. Mole weight: 178.23. | |
| PC Spacer Phosphoramidite | PC Spacer phosphoramidite can be used as an intermediate to link any modification reagent (which can be used as phosphoramidite) to the end of the oligonucleotide. After light cleavage, 5'-phosphate is generated on the DNA, making it suitable for further biotransformation, such as gene construction and cloning after ligation. Alternative Names: [4-(4,4'-Dimethoxytrityloxy)butyramidomethyl)-1-(2-nitrophenyl)-ethyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester; 1-[5-[[[4-[Bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester. CAS No. 653575-45-2. Molecular formula: C43H53N4O8P. Mole weight: 784.88. | |
| p-Cymene | p-Cymene is a monoterpene found in several essential oils. p-Cymene exhibits antinociceptive, immunomodulatory, vasorelaxant and neuroprotective activities. Alternative Names: 4-Isopropyltoluene; p-Isopropyltoluene; Dolcymene. CAS No. 99-87-6. Molecular formula: C10H14. Mole weight: 134.22. | |
| PD 144418 | PD 144418 is a very selective sigma 1 agent (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively), devoid of any significant affinity for other receptors and that sigma 1 site may modulate actions in the CNS. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration, and also attenuates cocaine-induced hyperactivity in mice. Alternative Names: PD 144418; PD144418; PD-144418; 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine. Grades: ≥98% by HPLC. CAS No. 154130-99-1. Molecular formula: C18H22N2O. Mole weight: 282.38. | |
| PD166866 | PD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD166866 has clear antiproliferative effects. Uses: Protein kinase inhibitors. Alternative Names: PD166866; PD-166866; PD 166866. Grades: 98%. CAS No. 192705-79-6. Molecular formula: C20H24N6O3. Mole weight: 396.45. | |
| PD-1/PD-L1-IN-23 | PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice. CAS No. 2597056-04-5. Molecular formula: C32H30BrCl2N3O6. Mole weight: 703.41. | |
| PD-1/PD-L1-IN-9 | PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model. Grades: 98%. CAS No. 2628506-54-5. Molecular formula: C22H24N2O2. Mole weight: 348.44. | |
| pdC-CE Phosphoramidite | pdC-CE Phosphoramidite is an essential reagent used in the synthesis of nucleic acids for biomedical research. Its high-quality and purity ensure efficient and reliable coupling during solid-phase oligonucleotide synthesis. This phosphoramidite is especially useful for the introduction of phosphodiester bonds in the presence of other modified nucleotides. Ideal for constructing therapeutic oligonucleotides targeting specific diseases. Alternative Names: 5'-Dimethoxytrityl-N4-diisobutylaminomethylidene-5-(1-Propynyl)-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 193631-87-7. Molecular formula: C51H67N6O7P. Mole weight: 907.1. | |
| P-DECYLOXYANILINE | P-DECYLOXYANILINE. Alternative Names: 4-(Decyloxy)aniline; 4-(decyloxy)-benzenamin; Aniline, p-(decyloxy)-; Benzenamine, 4-(decyloxy)-; M & B 2655; m&b2655; p-(decyloxy)-anilin; 4-N-DECYLOXYANILINE. CAS No. 39905-47-0. Molecular formula: C16H27NO. Mole weight: 249.39. | |
| P-DIVINYLBENZENE 85 | DVB can be co-polymerized with sulfur due to its high reactivity. It can be used as a cathode material in lithium-sulfur batteries. It can also be used as a cross-linker that increases the rigidity and reduces the template leakage of the molecular imprinted polymers (MIPs). DVB can be polymerized to form poly(divinylbenzene) that can be carbonized to fabricate activated carbon monoliths. Alternative Names: 1,4-diethenyl-benzen; 1,4-diethenylbenzene; 1,4-diethenyl-Benzene; benzene,1,4-diethenyl-; p-vinylstyrene; P-DIVINYLBENZENE 85. Grades: 95%. CAS No. 105-06-6. Molecular formula: C10H10. Mole weight: 130.1864. | |
| Peanut Oil | Peanut Oil is a non-polar solvent used as a delivery vehicle for lipophilic compounds. Extractives and their physically modified derivatives. It consists primarily of the glycerides of the fatty acids arachidic, behenic, lignoceric, linoleic, oleic, palmitic and stearic. (Arachishypogaea). Alternative Names: Peanut oil or Groundnut oil; Arachis hypogaea hypogaea seed oil; Arachis oil; Earthnut oil; Fats and Glyceridic oils, arachis; Fats and Glyceridic oils, groundnut; Fats and Glyceridic oils, peanut; Groundnut oil; Katchung oil; Peanut oils. CAS No. 8002-3-7. | |
| PEAR ACETATE | Pear acetate is a natural compound used in the fragrance industry. It is also being researched for potential therapeutic benefits in cancer treatment due to its ability to induce apoptosis in cancer cells. Alternative Names: 3-Nonen-1-ol, 1-acetate, (3Z)-, cis-3-Nonenyl acetate, PEAR ACETATE, z-3-Nonen-1-yl acetate. Grades: 95.0%. CAS No. 13049-88-2. Molecular formula: C11H20O2. Mole weight: 184.28. | |
| Pectic acid | Pectic acid, a polysaccharide residing in plant cell walls, possesses high credibility in biomedicine, treating ailments such as diabetes, cancer, and cholesterol build-up. Against the backdrop of a fascinating ability to bind with cholesterol and lipids in digestive tracts to reduce absorption, this macromolecule also exerts anti-inflammatory and antioxidant properties. Alternative Names: Methyl protopectin. CAS No. 9046-40-6. | |
| Pectin | D-Galacturonic acid is the main component of pectin, but some neutral sugars are also prevalent in pectin. The D-galacturonic acid units are linked together by α(1-4) glycosidic linkages. The polygalacturonic acid is partially esterified with methyl, and the free acid group can be partially or completely neutralized with sodium, potassium or ammonium ions. Pectin is commonly used as a stabilizer, a thickening agent and a gelling agent in food. Uses: Antidiarrheals. Alternative Names: Cesapectin; Poly-D-galacturonic acid methyl ester; Beta-Pectin; Cesapectin; Colyer pectin; Herbacel Citrus Fiber; Methoxypectin; Methyl pectin; Methyl pectinate; Pectinate; Pectinic acid; Pectins; Rhamnogalacturonan II; TIC Pretested Pre-hydrated 1694 Powder; Unipectin. CAS No. 9000-69-5. | |
| Pectinase | Pectinase. CAS No. 9032-75-1. | |
| PECTINESTERASE FROM ORANGE PEEL | PECTINESTERASE FROM ORANGE PEEL. Grades: 95%. CAS No. 9025-98-3. | |
| PefachromeTry | PefachromeTry. Alternative Names: Bz-Val-Gly-Arg-4-nitroanilide acetate, N-Benzoyl-L-valyl-glycyl-L-arginine-4-nitroanilide acetate. CAS No. 161572-28-7. Molecular formula: C28H38N8O8. Mole weight: 614.65. | |
| Peficitinib | Peficitinib is a potent JAK inhibitor with IC50 values of 3.9, 5.0, 0.71 and 4.8 nM for JAK1, JAK2, JAK3 and TYK2 enzyme activities, respectively. It inhibits the IL-2-induced proliferation of human T cells with IC50 value of 18 nM. Moreover, peficitinib is 14-fold more potent against JAK1/3 than JAK2/2 on the basis of EPO-induced proliferation of human leukemia cells. Peficitinib has been used for the treatment of psoriasis and rheumatoid arthritis. Uses: Inhibited jak1, jak2, jak3 and tyk2 enzyme activities with ic50 values of 3.9, 5.0, 0.71 and 4.8 nm, respectively; inhibited the il-2-induced proliferation of human t cells with an ic50 value of 18 nm. Alternative Names: ASP015K; ASP-015K; 4-[[(1R,3S)-5-hydroxy-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide. Grades: >98%. CAS No. 944118-01-8. Molecular formula: C18H22N4O2. Mole weight: 326.39. | |
| PEG 12 Dimethicone | PEG 12 Dimethicone is a PEG binded with Dimethicone, a silicone-based polymer used to give formulas a smooth feel, promote spreadability, and add lubrication. It acts as a surface tension depressant, hair conditioning agent, skin conditioning agent, wetting agent, emulsifier and foam builder in a wide variety of beauty products and cosmetics. | |
| PEG2000-DPPE | 16:0 PEG2000 PE is a polyethylene glycol (mPEG) phospholipid conjugate. Incorporation of PEG-modified lipid conjugates in liposomes facilitates the formation of sterically stabilized liposomes (SSL), which have low reticuloendothelial system (RES) uptake and prolong circulation lifetimes. These properties aid the PEGylated liposomes to spontaneously deliver drugs to targeted cells. Alternative Names: 16:0 PEG2000 PE; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt). Grades: >99%. CAS No. 474922-84-4. Molecular formula: C129H259N2O55P. Mole weight: 2749.38. | |
| PEG-25 PABA | PEG-25 PABA. CAS No. 116242-27-4. Molecular formula: (C2H4O)mult(C2H4O)mult(C2H4O)multC. Mole weight: 357.40. | |
| PEG-7 glyceryl cocoate | PEG-7 glyceryl cocoate. CAS No. 68201-46-7. | |
| Peganole | Derivative of Desoxypeganine from plants of the Zygophyllaceae family, a psychotomimetic agent on dogs and cats; acetylcholinesterase inhibitor. Alternative Names: Peganol; 4,5-dihydropyrrolidino[2,1-b]quinazolin-5-ol. Grades: >95 %. CAS No. 36101-54-9. Molecular formula: C11H12N2O. Mole weight: 188.23. | |
| Pegaptanib sodium | Pegaptanib sodium is an RNA aptamer directed against vascular endothelial growth factor (VEGF)-165, the VEGF isoform primarily responsible for pathological ocular neovascularization and vascular permeability. It can be used in the research of neovascular age-related macular degeneration (AMD). Alternative Names: Sodium 2,6-bis{[hydroxy(2-methoxyethoxy)methylidene]amino}-N-(5-{[hydroxy(methyl)phosphoryl]oxy}pentyl)hexanimidate; sodium; (2S)-N-[5-[hydroxy(methyl)phosphoryl]oxypentyl]-2,6-bis(2-methoxyethoxycarbonylamino)hexanimidate. CAS No. 222716-86-1. Molecular formula: C20H39N3NaO10P. Mole weight: 535.5. | |
| Pelargonidin Chloride | Pelargonidin, a galactoside of Pelargonidin, is a natural polyphenolic anthocyanidin with significant antioxidant effect. Alternative Names: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium Chloride; 3,4',5,7-Tetrahydroxyflavylium Chloride; Pelargonidin Chloride; Pelargonidol Chloride; 1-Benzopyrylium, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, chloride. Grades: >95%. CAS No. 134-04-3. Molecular formula: C15H11ClO5. Mole weight: 306.70. | |
| Pelcitoclax | Pelcitoclax, a potent Bcl-2/Bcl-xl inhibitor, has antineoplastic and pro-apoptotic effects. Alternative Names: APG-1252; NSC-835773; (R)-3-(1-(3-(4-(N-(4-(4-(3-(2-(4-chlorophenyl)-1-isopropyl-5-methyl-4-(methylsulfonyl)-1H-pyrrol-3-yl)-5-fluorophenyl)piperazin-1-yl)phenyl)sulfamoyl)-2-(trifluoromethylsulfonyl)phenylamino)-4-(phenylthio)butyl)piperidine-4-carbonyloxy)propylphosphonic acid; 4-Piperidinecarboxylic acid, 1-[(3R)-3-[[4-[[[4-[4-[3-[2-(4-chlorophenyl)-5-methyl-1-(1-methylethyl)-4-(methylsulfonyl)-1H-pyrrol-3-yl]-5-fluorophenyl]-1-piperazinyl]phenyl]amino]sulfonyl]-2-[(trifluoromethyl)sulfonyl]phenyl]amino]-4-(phenylthio)butyl]-, 3-phosphonopropyl ester. Grades: ≥95%. CAS No. 1619923-36-2. Molecular formula: C57H66ClF4N6O11PS4. Mole weight: 1281.85. | |
| Pelitinib | Pelitinib is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity. EKB-569 irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress these receptors. Alternative Names: EKB 569; EKB-569; EKB569; WAY-EKB 569; WAY-EKB569; WAY-EKB-569; CHEBI:38927; NSC729742; WAY-172569; WAY172569; WAY 172569; D05399; D 05399; D-05399. Grades: >98%. CAS No. 257933-82-7. Molecular formula: C24H23ClFN5O2. Mole weight: 467.929. | |
| Pelletierine | Pelletierine. Alternative Names: 2-Propanone, 1-(2-piperidinyl)-; Isopelletierine; (±)-1-(2-Piperidinyl)-2-propanone; 1-Piperidin-2-ylacetone; (±)-Pelletierine; 1-(2-Piperidinyl)acetone; DL-Pelletierine; 1-(2-Piperidinyl)-2-propanone. Grades: 95%. CAS No. 4396-1-4. Molecular formula: C8H15NO. Mole weight: 141.21. | |
| pembrolizumab | Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda) is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor. The drug was initially used in treating metastatic melanoma. Alternative Names: Anti-PD-1 monoclonal antibody - Merck; Humanised monoclonal IgG4 antibody against PD-1 - Merck; Keytruda; Lambrolizumab; MK-3475; MK 3475; MK3475; SCH-900475; SCH 900475; SCH900475. CAS No. 1374853-91-4. | |
| Pemigatinib | Pemigatinib is an inhibitor of fibroblast growth factor receptor types 1, 2, and 3 (FGFR1/2/3). Under the brand name Pemazyre, it is used as a medication for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma. Alternative Names: INCB054828. CAS No. 1513857-77-6. Molecular formula: C24H27F2N5O4. Mole weight: 487.5. | |
| Penciclovir | Penciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirusinfections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. Uses: Antiviral agents; reverse transcriptase inhibitors. Alternative Names: BRL-39123; BRL 39123; BRL39123; VSA 671; VSA671; VSA-671. Grades: >98%. CAS No. 39809-25-1. Molecular formula: C10H15N5O3. Mole weight: 253.26. | |
| Pendimethalin | Pendimethalin is a selective herbicide. Preemergence or postemergence in field corn, preemergence or postemergence incorporated use in potatoes, early postemergence use in rice, postemergence incorporated use in sorghum and preplant incorporated use in cotton, soybeans, tobacco, peanuts and sunflowers, controls most annual grasses and certain broadleaf weeds. Alternative Names: Penoxalin; Pendimethaline; Penoxaline; Prowl. CAS No. 40487-42-1. Molecular formula: C13H19N3O4. Mole weight: 281.31. | |
| Penethacillin hydroiodide | Penethacillin is a prodrug of Benzylpenicillin, an antimicrobial agent used for the treatment of bovine mastitis. Alternative Names: Benzylpenicillin Diethylaminoethyl Ester Hydroiodide; Diethyl(2-(6-(2-phenylacetamido)penicillanoyloxy)ethyl)ammonium iodide. Grades: > 95%. CAS No. 808-71-9. Molecular formula: C22H32IN3O4S. Mole weight: 561.48. | |
| Penicillanic Acid | Penicillanic Acid is a building block of penicillin. Uses: Anti-bacterial agents. Alternative Names: Penicillansaure; (2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid. Grades: 90%. CAS No. 87-53-6. Molecular formula: C8H11NO3S. Mole weight: 201.25. | |
| Penicillanyl ampicillinamide | An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Alternative Names: (2S,5R,6R)-6-{(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Molecular formula: C24H29N5O6S2. Mole weight: 547.65. | |
| Penicillin amidase | Penicillin amidase is an enzyme used commercially for the production of semisynthetic penicillins. Alternative Names: Amidase, penicillin; E.C. 3.5.1.11; Penicillin acylase; Benzylpenicillin acylase; Penicillin V acylase; Acylase, penicillin; Penicillin amidohydrolase; Penicillin G acylase. Grades: Activity wet form: 160U/g; Water content: 45%~60%. CAS No. 9014-6-6. | |
| Penicillin G Benzathine Tetrahydrate | An impurity of Penicillin G which is an antibacterial drug (intravenous use) against a wide range of bacteria. Uses: Anti-bacterial agents. Alternative Names: Penicillin G benzathine (USP); (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid compound with N,N'-dibenzylethylenediamine (2:1), tetrahydrate; Permapen (TN); Wycillin (TN); Bis[(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]N,N'-Bis(phenylmethyl)-1,2-ethanediamine Tetrahydrate; Bis[[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate] N,N'-Bis(phenylmethyl)-1,2-ethanediamine Tetrahydrate. Grades: 97%. CAS No. 41372-02-5. Molecular formula: C16H20N2.2(C16H18N2O4S).4H2O. Mole weight: 981.18. | |
| Penicillin Impurity 1 | Penicillin Impurity 1 is an impurity of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Alternative Names: (4S)-2t-((R)-amino-carboxy-methyl)-5,5-dimethyl-thiazolidine-4r-carboxylic acid. CAS No. 37727-80-3. Molecular formula: C8H14N2O4S. Mole weight: 234.27. | |
| Penicillin V sodium salt | Penicillin V sodium salt, the sodium salt form of Penicillin V, is an orally active penicillin that has been found to be an effective antibiotic against sorts of bacteria. Uses: Anti-bacterial agents. Alternative Names: Phenoxymethylpenicillin sodium; Beromysin sodium; 6-Phenoxymethylpenicillin sodium; 6-Phenoxyacetamidopenicillanic acid sodium salt; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-, (2S,5R,6R)-, monosodium salt. Grades: 95%. CAS No. 1098-87-9. Molecular formula: C16H17N2NaO5S. Mole weight: 372.37. | |
| Pent-2-yne-1,4-diol | Pent-2-yne-1,4-diol. CAS No. 927-57-1. Molecular formula: C5H8O2. Mole weight: 100.12. | |
| Pent-3-enal | Pent-3-enal. CAS No. 5604-55-7. Molecular formula: C5H8O. Mole weight: 84.12. | |
| Pentabromo(tetrabromophenoxy)benzene | Pentabromo(tetrabromophenoxy)benzene. Grades: 95%. CAS No. 63936-56-1. Molecular formula: C12HBr9O. Mole weight: 880.27200. | |
| Pentachlorophenol,Sodium Salt | Pentachlorophenol,Sodium Salt. Alternative Names: sodium; 2,3,4,5,6-pentachlorophenolate; hydrate; Pentachlorophenolsodiumsalt,hydrate; SCHEMBL11329861; MolPort-003-894-607. Grades: 95%. CAS No. 123333-54-0. Molecular formula: C6Cl5O. Mole weight: 306.333649. | |
| pentadecanal | pentadecanal. Alternative Names: 1-pentadecanal; n-pentadecanal. Grades: >97% by GC. CAS No. 2765-11-9. Molecular formula: C15H30O. Mole weight: 226.40. | |
| Pentadecanolide | Pentadecanolide (CAS# 106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen. Alternative Names: oxacyclohexadecan-2-one. Grades: 95 %. CAS No. 106-02-5. Molecular formula: C15H28O2. Mole weight: 240.38. | |
| Pentaerythritol dioleate | Pentaerythritol dioleate. Alternative Names: PENTAERYTHRITOL DIOLEATE; 9-Octadecenoicacid(Z)-,2,2-bis(hydroxymethyl)-1,3-propanediylester; 2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate; PENTAERYTHRITYL DIOLEATE; pentaerythritoldioeate; 9-Octadecenoic acid (9Z)-, 2,2-bis(hydroxymethyl)-1,3-propanediyl. CAS No. 25151-96-6. Molecular formula: C41H76O6. Mole weight: 665.04. | |
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