BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Perillaldehyde | Perillaldehyde is a natural organic compound widely used in the biomedical industry, effectively inhibiting the growth of various bacteria and fungi. It has shown promising potential in studying infectious diseases. Alternative Names: Perillyl aldehyde; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde. Grades: 95%. CAS No. 2111-75-3. Molecular formula: C10H14O. Mole weight: 150.211. |  |
| Perilla Ocymoides Leaf Extract | Perilla Ocymoides Leaf Extract is derived from the dry leaves of Perilla, a plant of the Lamiaceae. The main active ingredient is rosmarinic acid, which, as a phenolic acid compound, has a variety of biological activities. It can be used as cosmetics material. Alternative Names: Perilla frutescens, ext.; PERILLA OCYMOIDES LEAF EXTRACT; PERILLA OCYMOIDES SEED EXTRACT; Perilla frutescens, Extrakt; Perilla frutesens extract. Grades: 10:1. CAS No. 90082-61-4. | |
| Perilla oil | Perilla oil. Alternative Names: perilla leaf oil; PERILLA OIL. Grades: 95%. CAS No. 68153-38-8. | |
| Perilla seed oil | Perilla seed oil. CAS No. 6812-21-8. | |
| Perillyl Alcohol | Perillyl Alcohol, or POH, a monoterpene derived from the mevalonate pathway in plants, induces apoptosis in colon tumor cells. Alternative Names: Perillyl alcohol; Perilla alcohol; Perycorolle; POH; perillol; perillic alcohol; [(4S)-4-prop-1-en-2-ylcyclohexen-1-yl]methanol; (-)-p-mentha-1,8-dien-7-ol; (S)-perillyl alcohol; 1-cyclohexene-1-methanol, 4-(1-methylethenyl)-, (4S)-; 4-isopropenyl-cyclohex-1-ene-1-methanol; cyclohex-1-ene-1-methanol, 4(1-methylethenyl); dihydrocuminyl alcohol; NSC 641066; p-mentha-1,8-dien-7-ol; perilla alcohol. Grades: >98%. CAS No. 18457-55-1. Molecular formula: C10H16O. Mole weight: 152.237. | |
| Perindopril acyl-b-D-glucuronide | Perindopril acyl-b-D-glucuronide is an influential compound, holding significant usage in hypertension and cardiovascular ailments. It acts as an angiotensin-converting enzyme (ACE) inhibitor. Alternative Names: Perindopril Acyl-beta-D-glucuronide. CAS No. 120398-66-5. Molecular formula: C25H40N2O11. Mole weight: 544.60. | |
| Perindoprilat | Perindoprilat, the active metabolite of perindopril, is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor in vitro with IC50 values ranging between 1.5 and 3.2 nM. Uses: Angiotensin-converting enzyme inhibitors. Alternative Names: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid; [2S-[1[R*(R*)],2α,3aβ,7aβ]]-1-[2-[(1-Carboxybutyl)amino]-1- oxopropyl]octahydro-1H-indole-2-carboxylic Acid; S 9780; USP Perindopril Related Compound B. Grades: > 95%. CAS No. 95153-31-4. Molecular formula: C17H28N2O5. Mole weight: 340.42. | |
| Perindoprilat acyl-b-D-glucuronide | Perindoprilat acyl-b-D-glucuronide is a biologically active compound, serving as a key metabolite derived from the angiotensin-converting enzyme (ACE) inhibitor, Perindopril. Its utilization predominantly revolves around its potential to function as a biomarker in pharmacokinetic investigations, thereby enhancing our comprehension of Perindopril's metabolic processes and excretion. Alternative Names: Perindoprilat glucuronide; (2R,3R,4S,5S,6R)-2-[(2S,3aS,7aS)-1-[2-(1-carboxypropylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]oxy-3,4,5-trihydroxy-6-methyloxane-2-carboxylic acid; beta-D-Glucopyranuronic acid, 1-(1-(2-((1-carboxybutyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylate), (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-. CAS No. 120381-56-8. Molecular formula: C23H36N2O11. Mole weight: 516.54. | |
| Perindopril Erbumine | Perindopril Erbumine displays a higher binding affinity for the bradykinin binding sites than the angiotensin I binding sites of the angiotensin-converting enzyme (ACE) with bradykinin / angiotensin I selectivity ratio of 1.44. Uses: Angiotensin-converting enzyme inhibitors. Alternative Names: S9490-3. Grades: >98%. CAS No. 107133-36-8. Molecular formula: C19H32N2O5.C4H11N. Mole weight: 441.6. | |
| Perlite, expanded | Perlite, expanded. Alternative Names: Ceramic Sil 42-18; Dicalite 471; EP 100 (glass); Eurocell 140; Eurocell 300H; Eurocell A 140; Expanded perlite; Genulite M 105; Harborlite 200; Harborlite 2000S; Harborlite 205; Harborlite 635; Harborlite 700; Microfill 43H; Omyasphere 235T-FQ; Omyasphere TP 312FG; Perlite Microfill 43H; PEX 40; Pratliperl; Ryolex 3S; Sil-Cell 32; Silbrico 35-34; Silkleer 27M; Terra-Fil X 4; USA 444; USA 555; USA Fines. Grades: 95%. CAS No. 93763-70-3. Molecular formula: Al6H10K2Na2O76Si30. Mole weight: 2354.60. | |
| Permethrin | Permethrin is a synthetic pyrethroid insectide, affecting neuron membranes by prolonging sodium channel activation. It is used for the treatment of infestation with Sarcoptes scabiei (scabies). Alternative Names: 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid (3-Phenoxyphenyl)methyl Ester; m-Methoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Acticin; Adion; Ambush; FMC-33297; NIA-33297; Dichlorophenothrin; Diffusil H; Dragnet; Dragnet FT; Dragon; Imperator; Permanone; Spartan; Permethrin (Mixture of cis and trans Isomers); Transpermethrin; Ambush; FMC 33297; S-3151; FMC33297; S3151; S 3151. Grades: ≥ 90% (cis / trans mixture). CAS No. 52645-53-1. Molecular formula: C21H20Cl2O3. Mole weight: 391.29. | |
| Permethrin EP Impurity A | Permethrin EP Impurity A is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: 3-Phenoxytoluene; m-Phenoxytoluene; 3-Methyldiphenyl ether; 3-Methylphenyl Phenyl Ether; m-Methylphenyl Phenyl Ether; Benzene, 1-methyl-3-phenoxy-; Phenyl m-tolyl ether. Grades: ≥95%. CAS No. 3586-14-9. Molecular formula: C13H12O. Mole weight: 184.23. | |
| Permethrin EP Impurity B | Permethrin EP Impurity B is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: methyl (1RS,2RS)-2-(2,2-dichloroethenyl)-3,3-dimethylcyclopropane-1-carboxylate; Permethrin EP Impurity B (DCVC Methyl Ester) (Mixture of Diastereomers); Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, methyl ester; Methoxy Permethrinate; Methyl 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylate; Methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; Permethrinic acid methyl ester; 3-(2,2-Dichloroethenyl)-2,2-dimethyl-methyl Ester Cyclopropanecarboxylic Acid. Grades: ≥95%. CAS No. 61898-95-1. Molecular formula: C9H12Cl2O2. Mole weight: 223.10. | |
| Permethrin EP Impurity C | Permethrin EP Impurity C is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: 3-Phenoxybenzyl alcohol; Benzenemethanol, 3-phenoxy-; 3-Phenoxybenzenemethanol; Benzyl alcohol, m-phenoxy-; 1-Hydroxymethyl-3-phenoxybenzene; 3-(Hydroxymethyl)diphenyl ether; m-Phenoxybenzyl alcohol; Phenoxybenzyl alcohol; POB-AL. Grades: ≥95%. CAS No. 13826-35-2. Molecular formula: C13H12O2. Mole weight: 200.23. | |
| Permethrin EP Impurity D | Permethrin EP Impurity D is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: Benzaldehyde, 3-phenoxy-; 3-Formyldiphenyl Ether; 5-Phenoxybenzaldehyde; m-(Phenyloxy)benzaldehyde; m-Phenoxybenzaldehyde. Grades: ≥95%. CAS No. 39515-51-0. Molecular formula: C13H10O2. Mole weight: 198.22. | |
| Permethrin EP Impurity E | Permethrin EP Impurity E is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: 3-Phenoxybenzyl chloride; Benzene, 1-(chloromethyl)-3-phenoxy-; 1-Chloromethyl-3-phenoxybenzene; 3-Phenoxy-α-chlorotoluene; 3-Phenoxybenzyl Chloride; 3-Phenoxyphenylmethyl Chloride; m-Phenoxybenzyl Chloride; α-Chloro-m-tolyl Phenyl Ether; 3-(Chloromethyl)diphenyl ether; 3-(Chloromethyl)phenyl phenyl ether. Grades: ≥95%. CAS No. 53874-66-1. Molecular formula: C13H11ClO. Mole weight: 218.68. | |
| Permethrin EP Impurity F | Permethrin EP Impurity F is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: (1RS,2RS)-2-(2,2-dichloroethenyl)-3,3-dimethylcyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-; 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid (cis / trans mixture); 3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic Acid; 2,2-Dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic Acid; 3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropylcarboxylic Acid; DV-chrysanthemic Acid; Permethric Acid; Permethrinic Acid (cis / trans mixture). Grades: ≥95%. CAS No. 55701-05-8. Molecular formula: C8H10Cl2O2. Mole weight: 209.07. | |
| Permethrin EP Impurity G | Permethrin EP Impurity G is an impurity of Permethrin, which is a synthetic pyrethroid insecticide used in agriculture to protect livestock and crops, industrially to protect buildings, timber and aircraft, and pharmaceutically in the treatment of lice, scabies, and in the veterinary treatment of fleas and ticks. Alternative Names: 3-(phenoxyphenyl)methyl (1RS,2RS)-2-(chloroethynyl)-3,3-dimethylcyclopropane-1-carboxylate; Chloroacetylenic Permethrin; Cyclopropanecarboxylic acid, 3-(2-chloroethynyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester; Permethrin Impurity G; (3-Phenoxyphenyl)methyl 3-(2-chloroethynyl)-2,2-dimethylcyclopropanecarboxylate; Cyclopropanecarboxylic acid, 3-(chloroethynyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester. Grades: ≥95%. CAS No. 64964-54-1. Molecular formula: C21H19ClO3. Mole weight: 354.84. | |
| Pertuzumab | Pertuzumab is a humanized IgG1 monoclonal antibody and a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. Alternative Names: pertuzumab; 2C4; Immunoglobulin G1, anti-(human V (receptor)) (human-mouse monoclonal 2C4 heavy chain), disulfide with human-mouse monoclonal 2C4 kappa-chain, dimer; Omnitarg; Unii-K16aiq8ctm. Grades: 95%. CAS No. 380610-27-5. Mole weight: 145175.18. | |
| Peru balsam | Peru balsam. Alternative Names: BALSAM OF PERU; BALSAM PERU; Balsam Peru oil; BALSAM PERU RESINOID; FEMA 2116; FEMA 2117; PERU BALSAM; PERU BALSAM ALVA ESSENCE. CAS No. 8007-00-9. | |
| Peruvoside | Peruvoside is a cardenolide glycoside found in Thevetia peruviana. It has been used for the treatment of heart failure. Alternative Names: Encordin; Cannogenin thevetoside. Grades: 95%. CAS No. 1182-87-2. Molecular formula: C30H44O9. Mole weight: 548.66. | |
| Perylene Orange | Lumaogen F 40 is a fluorescent pigment. Alternative Names: Lumaogen F 40. Grades: >98.0%. CAS No. 82953-57-9. Molecular formula: C48H42N2O4. Mole weight: 710.87. | |
| Perylene Red | Perylene Red is a fluorescent dye. Alternative Names: Fluorescense red; Lumogen Red 300; KF-856; KF856; KF 856; N,N'-Bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxy-3,4,9,10-perylenetetracarboxylic Diimide. CAS No. 123174-58-3. Molecular formula: C72H58N2O8. Mole weight: 1079.2. | |
| Perylo[1,12-bcd]thiophene | Perylo[1,12-bcd]thiophene. CAS No. 31473-75-3. Molecular formula: C20H10S. Mole weight: 282.40. | |
| PE (Soy) | BOC Sciences provides high-quality PE (Soy) for your projects. Alternative Names: Phosphatidylethanolamines (soy); L-α-phosphatidylethanolamine (soybean). Grades: >98%. CAS No. 97281-51-1. Molecular formula: C39H74NO8P. Mole weight: 715.98. | |
| Petasin | Petasin, extracted from the genus Petasites, is a sesquiterpene. Alternative Names: (1R,2R,7S,8aR)-1,8a-dimethyl-7-(1-methylethenyl)-6-oxo-1,2,3,4,6,7,8,8a-octahydronaphthalen-2-yl (2Z)-2-methylbut-2-enoate; Petasol butenoate; O-Angeloylsencathenone. CAS No. 26577-85-5. Molecular formula: C20H28O3. Mole weight: 316.44. | |
| PETROLEUM ETHER, 150-200°C | PETROLEUM ETHER, 150-200°C. Grades: 95%. CAS No. 64742-49-0. Molecular formula: C6H14||||C6H14||||C6H14||||CH3CH(CH3)(CH2)2CH3||||C6H14. Mole weight: 86.18. | |
| Petroleum spirits | Petroleum spirits. Alternative Names: Petroleum, mineral spirits; Petroleum, spirit; Turpentine substitutes; White spirit; Amsco 140; Clerane 260; Coastal Pale Oil 105; Coating materials, vehicles, petroleum spirits; Finalan 40; HAWS; Kristallol K 30; LAWS; LAWS (solvent); LPA 210; Mineral spirits; Mineral Spirits A; Naphtha, petroleum spirits; New Solvent A; Nisseki A Solvent; Shellsol 340; Soltrol; Solvent oil 200; Spirdane D 40; Spirdane D 60; Spirits; Terlitol 16/18; Varsol 40; Varsol 60; White spirits. Grades: 95%. CAS No. 64475-85-0. Molecular formula: Tb85. Mole weight: 13508.66. | |
| Petunidin-3-arabinoside chloride | Petunidin-3-arabinoside chloride is a remarkable natural compound, renowned for its illustrious anti-inflammatory and antioxidant attributes. This prodigious compound aids in studying cardiovascular afflictions and select malignancies. Alternative Names: Petunidin 3-o-alpha-L-arabinopyranoside; 1-Benzopyrylium, 3-(arabinosyloxy)-2-(3,4-dihydroxy-5-methoxyphenyl)-5,7-dihydroxy-, chloride (1:1). Grades: > 95%. CAS No. 28500-03-0. Molecular formula: C21H21ClO11. Mole weight: 484.84. | |
| Petunidin 3-D-Glucoside | Petunidin 3-D-Glucoside, a glycoside form of the O-methylated anthocyanidin, Petundin, shows anti-oxidant activities as well as having potential cytoprotective effects. Alternative Names: Petunidin 3-O-β-D-Glucoside; 2-(3,4-dihydroxy-5-methoxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-1-benzopyrylium Chloride; 3-(Glucosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; 3-(β-D-Glucopyranosyloxy)-3',4',5,7-tetrahydroxy-5'-methoxyflavylium Chloride; Petunidin 3-O-β-D-Glucopyranoside; Petunidin 3-Monoglucoside; Petunidin 3-β-D-Monoglucoside. Grades: > 95%. CAS No. 6988-81-4. Molecular formula: C22H23O12Cl. Mole weight: 514.86. | |
| Petunidin-3-galactoside chloride | Petunidin-3-galactoside chloride is found in the fruits of Vaccinium myrtillus, and it has antioxidant activity. Grades: 95%. CAS No. 28500-02-9. Molecular formula: C22H25O12.Cl. Mole weight: 516.88. | |
| Pexidartinib (PLX3397) | Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R with IC50 of 20 nM, Kit with IC50 of 10 nM, and Flt3 with IC50 160 nM. Phase 3, respectively. Alternative Names: PLX3397; PLX-3397; PLX 3397; Pexidartinib. Grades: 98%. CAS No. 1029044-16-3. Molecular formula: C20H15ClF3N5. Mole weight: 417.81. | |
| PF-04447943 | PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and 18 nM) for human, rhesus and rat recombinant PDE9 respectively and high selectivity for PDE9 versus PDEs1-8 and 10-11. Alternative Names: PF-04447943; PF 04447943; PF04447943; PF-4447943; PF 4447943; PF4447943. Grades: >98%. CAS No. 1082744-20-4. Molecular formula: C20H25N7O2. Mole weight: 395.46. | |
| PF-04937319 | This active molecular is a glucokinase activator originated by Pfizer and EC50 value is 174 nM. PF-04937319 can improve glycemic control in adults with type 2 diabetes when applicated in conjunction with metformin and it can also maintain lower-glucose levels without it resulting in hypoglycemia. However,clinical trials were discontinued for Type 2 diabetes mellitus in 2016. Uses: Type 2 diabetes mellitus. Alternative Names: PF-04937319; PF04937319; PF 04937319; PF-4937319; PF 4937319; PF4937319; N,N-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide. Grades: 98%. CAS No. 1245603-92-2. Molecular formula: C22H20N6O4. Mole weight: 432.44. | |
| PF-05082566 | A fully humanized monoclonal antibody (mAb) that stimulates signaling through 4-1BB (CD-137), a protein expressed in many immune cells. Alternative Names: Utomilumab; PF-2566; PF-5082566; PF 2566; PF 5082566; PF2566; PF5082566. CAS No. 1417318-27-4. | |
| PF 05105679 | PF-05105679 is a selective TRPM8 Antagonist with clinical efficacy in cold-related pain. IC50 value is 103 nM. It shows >100-fold selectivity for TRPM8 over a panel of receptors, ion channels and enzymes, including TRPV1 and TRPA1 ion channels. In Sep 2011, Pfizer completed a phase I trial for the treatment of neuropathic pain in Healthy volunteers in Belgium. Uses: Neuropathic pain;cold-related pain. Alternative Names: PF-05105679; PF 05105679; PF05105679; PF-5105679; PF 5105679; PF5105679. 3-[[[(1R)-1-(4-Fluorophenyl)ethyl](3-quinolinylcarbonyl)amino]methyl]-benzoic acid, PF05105679, [(R)-3-[(1-(4-fluorophenyl)ethyl)(quinolin-3-ylcarbonyl)amino]methylbenzoic acid. Grades: 98%. CAS No. 1398583-31-7. Molecular formula: C26H21FN2O3. Mole weight: 428.45. | |
| PF 05175157 | PF-05175157 is a selective inhibitor of both acetyl-CoA carboxylase isoform ACC1 and isoform ACC2 dominant. IC50 values are 27 nM and 33 nM, respectively. It was originated by Pfizer. ACC inihibitors can inhibit de novo lipogenesis and increase β-oxidation of long-chain fatty acids. In Feb 2015, Phase-II for Type-2 diabetes mellitus in USA was discontinued. Uses: Type 2 diabetes mellitus. Alternative Names: PF-05175157; PF05175157; 1,4-Dihydro-1'-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one. Grades: 98%. CAS No. 1301214-47-0. Molecular formula: C23H27N5O2. Mole weight: 405.50. | |
| PF 06409577 | PF 06409577 is a potent and selective allosteric activator of AMPK (EC50 values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively) for the potential treatment of diabetic nephropathy. PF-06409577 showed efficacy in a preclinical model of diabetic nephropathy. Alternative Names: PF-06409577; PF06409577; PF-6409577; PF6409577; PF 6409577. Grades: ≥98% by HPLC. CAS No. 1467057-23-3. Molecular formula: C19H16ClNO3. Mole weight: 341.79. | |
| PF-06446846 hydrochloride | PF-06446846 is an orally bioavailable inhibitor of PCSK9. PF-06446846 inhibits translation of PCSK9 by inducing the ribosome to stall around codon 34, mediated by the sequence of the nascent chain within the exit tunnel. Alternative Names: PF846; PF 06446846 hydrochloride; PF06446846 hydrochloride. CAS No. 1632250-50-0. Molecular formula: C22H21Cl2N7O. Mole weight: 470.35. | |
| PF-06650833 | PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), which is an omnipresently expressed serine / threonine kinase involved in the regulation of innate immunity. PF-06650833 is useful for the treatment of autoimmune and inflammatory diseases associated with lnterleukin-1 Receptor Associated Kinase (IRAK) and more particularly modulates the function of IRAK. It is undergoing testing in a Phase II clinical study. Alternative Names: zimlovisertib; PF 06650833; PF06650833. CAS No. 1817626-54-2. Molecular formula: C18H20FN3O4. Mole weight: 361.373. | |
| PF-06651600 | PF-06651600 is a selective JAK3 inhibitor with IC50 value of 0.346 nM. It was shown to inhibit Th1 and Th17 cell differentiation and function in vitro. Alternative Names: Ritlecitinib; PF 06651600; PF06651600; 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-. Grades: >98%. CAS No. 1792180-81-4. Molecular formula: C15H19N5O. Mole weight: 285.351. | |
| PF-07321332 | PF-07321332 is an orally available SARS-CoV 3C-like protease (3CLPRO) inhibitor. 3C-like protease (3CLPRO) is the main protease found in coronaviruses, which cleaves the coronavirus polyprotein at eleven conserved sites. PF-07321332 has demonstrated oral activity in a mouse-adapted SARS-CoV-2 model and has achieved oral plasma concentrations exceeding the in vitro antiviral cell potency in a phase I clinical trial in healthy human participants. Alternative Names: PF 07321332; PF07321332. Grades: 98%. CAS No. 2628280-40-8. Molecular formula: C23H32F3N5O4. Mole weight: 499.53. | |
| PF 5081090 | PF 5081090, a pyridone methylsulfone hydroxamate, is a potent antibacterial agent which disrupts lipid bilayer synthesis through inhibition of LpxC (IC50 = 1.1 nM in Pseudomonas aeruginosa). Alternative Names: PF 5081090; PF5081090; PF-5081090; (α R)-4-(2-Fluoro-4-methoxyphenyl)-N-hydroxy-α-methyl-α-(methylsulfonyl)-2-oxo-1(2H)-pyridinebutanamide; (2R)-4-[4-(2-Fluoro-4-methoxyphenyl)-2-oxo-2H-pyridin-1-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide. Grades: ≥98% by HPLC. CAS No. 1312473-63-4. Molecular formula: C18H21FN2O6S. Mole weight: 412.43. | |
| PF-5190457 | PF-5190457 is a selective Growth hormone secretagogue receptor inverse agonist and it can increase insulin secretion in glucose-stimulated human islets. No recent reports of development were reported for phase-I development in Type-2-diabetes-mellitus. Uses: Type 2 diabetes mellitus. Alternative Names: PF-5190457; PF 5190457; PF5190457; PF-05190457; PF05190457; PF 05190457; (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethan-1-one. Grades: 95%. CAS No. 1334782-79-4. Molecular formula: C29H32N6OS. Mole weight: 512.67. | |
| PF-543 hydrochloride | The hydrochloride salt form of PF-543, a novel SphK1 inhibitor that could exhibit activity in induceing necrosis in human colorectal cancer cells in biological studies. IC50: 2 nM; Ki: 3.6 nM. Alternative Names: PF-543 hydrochloride; PF 543 hydrochloride; PF543 hydrochloride; (2R)-1-[[4-[[3-Methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2-pyrrolidinemethanol Hydrochloride. Grades: 98%. CAS No. 1706522-79-3. Molecular formula: C27H31NO4S.HCl. Mole weight: 502.07. | |
| PF-8380 | PF-8380 blocks inflammation-induced LPA synthesis. PF-8380 works both in vitro and in vivo through direct inhibition of autotaxin. In human whole blood PF-8380 inhibited autotaxin with an IC50 of 101 nM. Inhibition of ATX by PF-8380 led to decreased invasion and enhanced radiosensitization of GBM cells. Radiation-induced activation of Akt was abrogated by inhibition of ATX. Furthermore, inhibition of ATX led to diminished tumor vascularity and delayed tumor growth. PF-8380 can serve as a tool compound for elucidating LPA's role in inflammation. Alternative Names: 1-Piperazinecarboxylic acid, 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-, (3,5-dichlorophenyl)methyl ester; PF8380; PF 8380; (3,5-Dichlorophenyl)methyl 4-[3-(2,3-dihydro-2-oxo-6-benzoxazolyl)-3-oxopropyl]-1-piperazinecarboxylate; 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester. Grades: ≥95%. CAS No. 1144035-53-9. Molecular formula: C22H21Cl2N3O5. Mole weight: 478.33. | |
| PF-9363 | PF-9363 is a first-in-class inhibitor of KAT6A/KAT6B. PF-9363 exhibits potent anti-tumor activity in several ER+ breast cancer cell lines. Alternative Names: CTx-648; CTX-3648; 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide. Grades: 98%. CAS No. 2569009-58-9. Molecular formula: C20H20N4O6S. Mole weight: 444.46. | |
| PFI-90 | PFI-90 is a selective inhibitor of the histone demethylase KDM3B. PFI-90 was shown to induce apoptosis and cell differentiation, resulting in tumor cell death. Alternative Names: N'-(pyridin-2-yl)pyridine-2-carbohydrazide; 2-Pyridinecarboxylic acid, 2-(2-pyridinyl)hydrazide. Grades: 98%. CAS No. 53995-62-3. Molecular formula: C11H10N4O. Mole weight: 214.22. | |
| PFK-158 | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase / fructose-2,6-bisphosphatases (PFK-2 / FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Alternative Names: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. | |
| PGP-4008 | PGP-4008 is a selective P-glycoprotein (P-gp) inhibitor without modulating multidrug resistance-related protein 1 (MRP1). In combination with doxorubicin, PGP-4008 inhibited tumor growth in a murine syngeneic Pgp-mediated MDR solid tumor model. Alternative Names: N-(1-Benzyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide. Grades: ≥95%. CAS No. 365565-02-2. Molecular formula: C26H23N3O. Mole weight: 393.5. | |
| pGpG | pGpG is a STING agonist negative control and c-diGMP metabolite. Alternative Names: P; -(5'-Guanosyl)-P; -(5'-guanosyl)-(3'→5')-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 33008-99-0. Molecular formula: C20H26N10O15P2(free acid). Mole weight: 708.43 (free acid). | |
| Phanquinone | Phanquinone is an antiamoebic dysentery and bacillary dysentery drug that is active against a variety of gram-positive and gram-negative organisms. Alternative Names: Phenanthrolinedione; 11925C; 4,7-Phenanthroline-5,6-quinone; CIBA 11925; Enthobex; Entobex; Entronon; Phanchinone; Phanquinonum; Phanquone. Grades: 98%. CAS No. 84-12-8. Molecular formula: C12H6N2O2. Mole weight: 210.19. | |
| Pharmaceutical natural products, licorice | Licorice, derived from the root of the Glycyrrhiza glabra plant, is a versatile ingredient with a long history of use in traditional medicine, skincare, and dietary supplements. It offers numerous benefits including anti-inflammatory, antimicrobial, and antioxidant properties, making it effective for digestive health by treating acid reflux, ulcers, and gastritis, while also supporting skin health by reducing hyperpigmentation, soothing irritation, and promoting wound healing. Licorice is known for its expectorant properties that help with respiratory issues like coughs and bronchitis, and it can boost the immune system to fight infections. However, it contains glycyrrhizin, which can cause side effects such as high blood pressure, low potassium levels, and hormonal imbalances, especially with prolonged use. Uses: Anti-oxidant agents, anti-inflammation agents. Alternative Names: Licorice, ext.; FM 100; FM 100 (extract); Gan cao; Gan Zao; Gancao; GanZao; Glycyrrhiza extract; Glycyrrhizae radix; Kanzoh; Kanzou; Lacrinat; Licorice; Licorice (pharmaceutical); Licorice extract; Licorice root; Licorice root ext.; Licorice root extract; Liquiritiae radix; Liquorice root ext.; Liquorice root extract; LX 103; Natural products, pharmaceutical, Glycyrrhizae radix; Natural products. Grades: powder. CAS No. 68916-91-6. | |
| PH Dane-salt | PH Dane-salt. Grades: 95%. CAS No. 69416-61-1. Molecular formula: C13H14KNO5. Mole weight: 303.35. | |
| Phenanthridinium,3-amino-8-[3-[3-(aminoiminomethyl)phenyl]-2-triazen-1-yl]-5-ethyl-6-phenyl- | Phenanthridinium,3-amino-8-[3-[3-(aminoiminomethyl)phenyl]-2-triazen-1-yl]-5-ethyl-6-phenyl-. CAS No. 20438-03-3. Molecular formula: C28H26 N7. Mole weight: 460.5524. | |
| PHENAZO | PHENAZO. CAS No. 3687-26-1. Molecular formula: C24H16N6O6. Mole weight: 484.42. | |
| Phenethyl cinnamate | Phenethyl cinnamate is a natural product found in Alnus firma and Alnus pendula. Alternative Names: 2-Propenoic acid, 3-phenyl-, 2-phenylethyl ester; Cinnamic acid, phenethyl ester; 2-Phenylethyl 3-phenyl-2-propenoate; 2-Phenylethyl cinnamate; Benzylcarbinyl cinnamate; NSC 16962; β-Phenethyl cinnamate; β-Phenylethyl cinnamate. Grades: 98%. CAS No. 103-53-7. Molecular formula: C17H16O2. Mole weight: 252.31. | |
| Phenethyl decanoate | Phenethyl decanoate. CAS No. 61810-55-7. Molecular formula: C18H28O2. Mole weight: 276.41372. | |
| PHENETHYLDIMETHYL(DIMETHYLAMINO)SILANE | PHENETHYLDIMETHYL(DIMETHYLAMINO)SILANE. Alternative Names: PHENETHYLDIMETHYL(DIMETHYLAMINO)SILANE. CAS No. 181231-68-5. Molecular formula: C12H21NSi. Mole weight: 207.39. | |
| Phenethyl isobutyrate | Phenethyl isobutyrate (CAS# 103-48-0 ) is a useful research chemical. Alternative Names: 2-phenylethyl 2-methylpropanoate. CAS No. 103-48-0. Molecular formula: C12H16O2. Mole weight: 192.25. | |
| Phenethyl isothiocyanate | Phenethyl isothiocyanate (CAS# 2257-09-2) is a compound useful in organic synthesis. Alternative Names: 2-isothiocyanatoethylbenzene. CAS No. 2257-9-2. Molecular formula: C9H9NS. Mole weight: 163.24. | |
| Phenethyl nonanoate | Phenethyl nonanoate. CAS No. 57943-67-6. Molecular formula: C17H26O2. Mole weight: 262.40. | |
| Pheniramine Maleate | Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. Uses: Anti-allergic agents. Grades: >98%. CAS No. 132-20-7. Molecular formula: C16H20N2.C4H4O4. Mole weight: 356.42. | |
| Phenol 2,4-disulfonic acid | Phenol 2,4-disulfonic acid. Alternative Names: 3-Benzenedisulfonicacid,4-hydroxy-1; 4-hydroxy-3-benzenedisulfonicacid; 4-Hydroxybenzenedisulfonicacid; Phenol-2,4-disulfonicacid; PHENOLDISULFONIC ACID; Phenol disulfonic acid solution; PHENOLDISULPHONIC ACID; 4-hydroxybenzene-1,3-disulphonic acid. CAS No. 96-77-5. Molecular formula: C6H6O7S2. Mole weight: 254.24. | |
| Phenol-2-sulfonic acid | Phenol-2-sulfonic acid. Alternative Names: o-hydroxybenzenesulphonic acid; Phenol-2-sulfonic acid. Grades: 95%. CAS No. 609-46-1. Molecular formula: C6H6O4S. Mole weight: 174.17444. | |
| Phenol,4-(aminomethyl)-2,6-dimethoxy- | Phenol,4-(aminomethyl)-2,6-dimethoxy-. Alternative Names: 3,5,DIMETHOXY-4-HYDROXYBENZYLAMINE. CAS No. 4973-51-7. Molecular formula: C9H13 N O3. Mole weight: 183.2. | |
| Phenol, 4-dodecyl-,branched | Phenol, 4-dodecyl-,branched. Alternative Names: P-LAURYLPHENOL; PARA-DODECYLPHENOL; P-DODECYLPHENOL; PDDP; Dodecylphenol; 4-DODECYLPHENOL. Grades: 95%. CAS No. 210555-94-5. Molecular formula: C18H30O. Mole weight: 262.4302. | |
| Phenol, dimethyl-, 1,1',1''-phosphate | Phenol, dimethyl-,1,1',1''-phosphate, a highly sought-after compound in the biomedical sector, is renowned for its promising efficacy in combatting specific ailments. Extensively researched for its intricate pharmacodynamic characteristics, this substance holds significant promise for therapeutic intervention across diverse pathologies. Alternative Names: Trixylenyl phosphate; Trixylyl phosphate; coalitentp; dimethylphenolphosphate (3:1); dimethyl-phenophosphate (3:1); ivviol-3; Phenol, dimethyl-, phosphate (3:1); phosflex179. CAS No. 25155-23-1. Molecular formula: C24H27O4P. Mole weight: 410.48. | |
| Phenol-formaldehyde resin | thermoset resins (PF) are synthetic polymers obtained by the reaction of phenol or substituted phenol with formaldehyde. Used as the basis for Bakelite, PFs were the first commercial synthetic resins (plastics). They have been widely used for the production of molded products including billiard balls, laboratory countertops, and as coatings and adhesives. They were at one time the primary material used for the production of circuit boards but have been largely replaced with epoxy resins and fiberglass cloth, as with fire-resistant FR-4 circuit board materials.There are two main production methods. One reacts phenol and formaldehyde directly to produce a thermosetting network polymer, while the other restricts the formaldehyde to produce a prepolymer known as novolac which can be moulded and then cured with the addition of more formaldehyde and heat. There are many variations in both production and input materials that are used to produce a wide variety of resins for special purposes. Alternative Names: ormaldehyde-phenol copolymer; Phenolic resin; Phenol, polymer with formaldehyde; Formaldehyde, phenol polymer; Paraformaldehyde, phenol polymer. CAS No. 9003-35-4. | |
| Phenolic resin, rosin modified 2112 | Phenolic resin, rosin modified 2112. CAS No. 68152-70-5. Molecular formula: (C15H16O2.C3H8O3.CH2O.W99)x. | |
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