BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
(±)-trans-4-Phenylpyrrolidine-3-carboxylic acid hydrochloride. Alternative Names: (±)-trans-4-Phenylpyrrolidine-3-carboxylic acid HCl. Grades: ≥ 98% by NMR. CAS No. 1217702-99-2. Molecular formula: C11H14ClNO2. Mole weight: 227.69.
trans-beta-D-Glucopyranosyl methylacetoacetate
trans-beta-D-Glucopyranosyl methylacetoacetate is an intriguing derivative of glucose illuminating a path towards revolutionizing the research of diabetes and other intertwined metabolic ailments. It showcases propitious characteristics for precisely modulating the intricate web of glucose metabolism and sensitizing insulin responsiveness. Alternative Names: [(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] 2-methyl-3-oxobutanoate; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl 2-methyl-3-oxobutanoate. CAS No. 55018-21-8. Molecular formula: C11H18O8. Mole weight: 278.26.
trans-Caffeic acid 3-O-b-D-glucuronide
Caffeic acid 3-O-b-D-glucuronide, a highly acclaimed biomedicine in the field, showcases remarkable capabilities as an antioxidant agent, effectively combating ailments linked to oxidative stress. By demonstrating profound therapeutic potential, this compound stands as a promising remedy against inflammatory conditions, cardiovascular ailments, and select malignancies. Moreover, its inherent status as a natural phenolic compound endows it with immense applicability in diverse biomedical domains. Alternative Names: (E)-Caffeic acid 3-O-β-D-glucuronide; 5-[(1E)-2-Carboxyethenyl]-2-hydroxyphenyl β-D-glucopyranosiduronic acid. CAS No. 1093679-73-2. Molecular formula: C15H16O10. Mole weight: 356.28.
trans-Resveratrol 4-O-b-D-glucuronide
Trans-Resveratrol 4-O-b-D-glucuronide, a bioactive compound discovered in both red wine and grapes, holds significant potential in the realm of disease treatment, ranging from cardiovascular and neurodegenerative disorders to cancer. Additionally, this multi-talented compund boasts impressive anti-inflammatory and antioxidant abilities. It's these rare attributes that make trans-Resveratrol 4-O-b-D-glucuronide an invaluable ingredient in cosmetics and supplements alike. Alternative Names: 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]phenyl β-D-glucopyranosiduronic acid; Resveratrol 4'-O-glucuronide; trans-Resveratrol 4'-glucuronide; trans-Resveratrol 4'-O-glucuronide. CAS No. 387372-20-5. Molecular formula: C20H20O9. Mole weight: 404.37.
trans-Zeatin-7-glucoside
Trans-Zeatin-7-glucoside, a phytohormone of the cytokinin family, has been rigorously studied for its capacity to enhance plant growth and development. Furthermore, this crucial molecule has shown immense promise in the neurodegenerative therapeutic domain. Pathologies like Alzheimer's and Parkinson's have been curbed by trans-Zeatin-7-glucoside's medicinal capability making it a pivotal molecule for those who seek to enhance the health and wellbeing of both plants and animals alike. Alternative Names: 6-((E)-4-Hydroxy-3-methylbut-2-enylamino)-7-b-D-glucopyranosyl purine; (2E)-4-[(7-β-D-Glucopyranosyl-7H-purin-6-yl)amino]-2-methyl-2-buten-1-ol; 2-Buten-1-ol, 4-[(7-β-D-glucopyranosyl-7H-purin-6-yl)amino]-2-methyl-, (E)-; 7-Glucosylzeatin; 7-β-D-Glucopyranosylzeatin; Raphanatin; Zeatin 7-glucopyranoside; Zeatin 7-glucoside; Zeatin-7-β-D-glucopyranoside. CAS No. 38165-56-9. Molecular formula: C16H23N5O6. Mole weight: 381.38.
trans-Zeatin-9-glucoside
trans-Zeatin-9-glucoside is a pivotal compound widely utilized in the research of diverse ailments like chronic inflammation, oxidative stress and cellular impairment. By modulating crucial cellular mechanisms, it aids in studying manifestations linked to cardiovascular disorders and neurodegenerative pathologies. Alternative Names: 6-((E)-4-hydroxy-3-methylbut-2-enylamino)-9-b-D-glucopyranosylpurine. CAS No. 51255-96-0. Molecular formula: C16H23N5O6. Mole weight: 381.38.
trans-Zeatin-9-glucoside-o-glucoside
Trans-zeatin-9-glucoside-o-glucoside, a plant hormone, is a growth regulator with extensive therapeutic potential in cancer and diabetes through its effect on inhibiting cell growth. It is also implicated in the acceleration of wound healing and cognitive improvements. Recent studies have revealed its intricate and diverse molecular mechanisms, shedding light on new prospects for medical applications. Alternative Names: 6-((E)-4-b-D-Glucopyranosyloxy-3-methylbut-2-enylamino)-9-b-D-glucopyranosylpurine; (2E)-4-[(9-β-D-Glucopyranosyl-9H-purin-6-yl)amino]-2-methyl-2-buten-1-yl β-D-glucopyranoside; β-D-Glucopyranoside, 4-[(9-β-D-glucopyranosyl-9H-purin-6-yl)amino]-2-methyl-2-butenyl, (E)-. CAS No. 115921-05-6. Molecular formula: C22H33N5O11. Mole weight: 543.52.
trans-Zeatin-9-glucuronide
trans-Zeatin-9-glucuronide is a highly efficacious and medically significant compound, finding extensive employment in studying diverse ailments such as arthritand neurodegenerative disorders. It has commendable anti-inflammatory attributes. Molecular formula: C16H21N5O7. Mole weight: 395.37.
trans-Zeatin-O-glucoside Riboside
Trans-Zeatin-O-glucoside Riboside is useful in biological study for accumulation pattern of endogenous cytokinins and phenolics, in which different organs of 1-year-old cytokinin pre-incubated plants where occurrence, distribution and levels of cytokinins and bioactive phenolic compounds were strongly influenced by cytokinins pre-treatment in leaves, roots and bulbs of 1-yr-old Tulbaghia simmleri during micropropagation. Alternative Names: N-[(2E)-4-(β-D-Glucopyranosyloxy)-3-methyl-2-buten-1-yl]adenosine; Glucosyl Ribosylzeatin; O-Glucosyl Zeatin Riboside; O-β-D-Glucopyranosylzeatin Riboside;Ribosylzeatin O-Glucoside; Zeatin Riboside O-Glucoside; Zeatin Riboside Glucoside; Zeatin Riboside β-D-Glucoside; Zeatin-O-glucoside Riboside; trans-Zeatin Riboside O-Glucoside; trans-Zeatin-O-glucoside Riboside; N-[(2E)-4-(β-D-Glucopyranosyloxy)-3-methyl-2-buten-1-yl]-adenosine; tZROG. CAS No. 62512-97-4. Molecular formula: C21H31N5O10. Mole weight: 513.5.
trans-Zeatin-o-glucuronide
trans-Zeatin-o-glucuronide is a biomedically significant product, classified as a glucuronide conjugate of the pivotal cytokinin trans-zeatin. This compound exerts a critical influence on plant growth and development. Leveraging its distinctive structural attributes, trans-zeatin-o-glucuronide aids in the research of cancer, diabetes and neurodegenerative ailments. Alternative Names: trans-Zeatin-O-beta-D-glucuronide; 147663-51-2. CAS No. 147663-51-2. Molecular formula: C16H21N5O7. Mole weight: 395.37.
trans-Zeatin riboside-5'-monophosphate
trans-Zeatin riboside-5'-monophosphate is an invaluable biochemical compound extensively employed in the research of an array of age-related afflictions, including Alzheimer's, Parkinson's, and cardiovascular maladies. Alternative Names: 5'-Adenylic acid, N-[(2E)-4-hydroxy-3-methyl-2-buten-1-yl]-; 5'-Adenylic acid, N-(4-hydroxy-3-methyl-2-butenyl)-, (E)-; 5'-Adenylic acid, N-[(2E)-4-hydroxy-3-methyl-2-butenyl]-; Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, 5'-(dihydrogen phosphate), (E)-; N-[(2E)-4-Hydroxy-3-methyl-2-buten-1-yl]-5'-adenylic acid; 9-β-D-Ribofuranosylzeatin-5'-phosphate; Ribosylzeatin 5'-monophosphate; trans-Zeatin-9-riboside-5'-monophosphate; Zeatin 5'-ribotide; Zeatin 9-β-ribonucleoside 5'-monophosphate; Zeatin ribonucleotide; Zeatin riboside 5'-monophosphate; Zeatin riboside 5'-phosphate; Zeatin ribotide; Zeatin-9-β-D-ribofuranoside 5'-monophosphate. CAS No. 25615-16-1. Molecular formula: C15H22N5O8P. Mole weight: 431.34.
trans-Zeatin riboside-5'-monophosphate disodium salt
trans-Zeatin riboside-5'-monophosphate sodium salt is renowned as a pivotal compound constituent, aptly catering to the research demands of diverse ailments, encompassing malignancies and immune-mediated afflictions. Alternative Names: trans-Zeatin riboside-5'-monophosphate sodium salt; 5'-Adenylic acid, N-[(2E)-4-hydroxy-3-methyl-2-butenyl]-, disodium salt; 5'-Adenylic acid, N-(4-hydroxy-3-methyl-2-butenyl)-, disodium salt, (E)-; 6-((E)-4-hydroxy-3-methylbut-2-enylamino)-9-b-D-ribofuranosyl-purine-5'-monophosphate disodium salt; Zeatin ribonucleotide disodium salt. Grades: ≥95%. CAS No. 174063-91-3. Molecular formula: C15H20N5Na2O8P. Mole weight: 475.30.
Trebler Phosphoramidite
Trebler Phosphoramidite, a molecule specifically utilized in the biomedicine industry, is widely employed for synthesizing oligonucleotides that chiefly involve DNA sequences. This particular component acts as a foundation to create modified DNA sequences that exhibit effective application in treating a plethora of diseases. Its distinctive chemical architecture conveys exceptional traits essential for drug delivery processes such as heightened stability, resistance to nucleases, and remarkable binding features. Alternative Names: Tris-2,2,2-[3-(4,4'-dimethoxytrityloxy)propyloxymethyl]ethyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C86H101N2O14P. Mole weight: 1417.72.
Trehalose-6-phosphate disodium salt is a significantly influential compound, existing as the disodium salt configuration of trehalose-6-phosphate. Trehalose-6-phosphate fundamentally governs metabolic processes and has garnered extensive research in managing metabolic irregularities, including diabetes and obesity. Alternative Names: α-D-Glucopyranoside, α-D-glucopyranosyl, 6-(dihydrogen phosphate), sodium salt (1:2); α-D-Glucopyranoside, α-D-glucopyranosyl, 6-(dihydrogen phosphate), disodium salt; Trehalose, 6-(dihydrogen phosphate) disodium salt; Trehalose, 6-phosphate disodium salt; α,α-Trehalose 6-phosphate disodium salt. Molecular formula: C12H21O14PNa2. Mole weight: 466.24.
Trehalose-6-vanadate
Trehalose-6-vanadate.
Trehalose octaacetate
Trehalose octaacetate, an esteemed biomedical marvel, takes center stage in combating the realm of neurodegenerative afflictions. Embarking on a noble expedition to tame the vicious Alzheimer's and Parkinson's, this formidable substance assumes the unsung role of a neuroprotective sentinel. Alternative Names: 2,3,4,6,2,3,4,6-Octa-O-acetyl-a,a-trehalose. CAS No. 25018-27-3. Molecular formula: C28H38O19. Mole weight: 678.59.
Tremulacin
Tremulacin is a natural product found in Itoa orientalis, Dovyalis hebecarpa, and Populus tremuloides. Alternative Names: β-D-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl, 2-benzoate. Grades: 95%. CAS No. 29836-40-6. Molecular formula: C27H28O11. Mole weight: 528.50.
Triantennary GalNAc Ligand
Triantennary GalNAc Ligand is a ligand conjugated to biotin, antibodies, or fragments of antibodies to generate a new class of degraders. It has been used in targeted drug delivery, such as oligonucleotide therapy. Alternative Names: Tri-GalNAc(OAc)3 Cbz; 5-Oxa-2,9,13-triazaoctadecanoic acid, 8,14-dioxo-3,3-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-18-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, phenylmethyl ester; Phenylmethyl 8,14-dioxo-3,3-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-18-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-5-oxa-2,9,13-triazaoctadecanoate; Tri-b-GalNAcAc3-NHCbz; Tri-GalNAc (Cbz, peracetylated); Tris-GalNAc (Cbz, peracetylated); Tris-β-GalNAc-Cbz (perac); Tris-GalNAcAc3-Cbz; tri-β-GalNAcAc3-NHCbz; Triantennary β-GalNAcAc3-NHCbz. Grades: >95%. CAS No. 1159408-63-5. Molecular formula: C87H134N10O38. Mole weight: 1928.04.
Tri-b-GalNAc-6-aminohexanoate
Tri-b-GalNAc-6-aminohexanoate is a synthetic ligand designed to target the asialoglycoprotein receptor (ASGPR) on hepatocytes. It features a trivalent GalNAc cluster attached to a 6-aminohexanoate linker, which facilitates efficient binding to ASGPR and enhances the delivery of therapeutic agents to liver cells. This compound is commonly used in the development of targeted therapies for liver diseases, including RNA interference (RNAi) and antisense oligonucleotide (ASO) applications. Alternative Names: Tri-GalNAc-hexamine; Tris-GalNAc-(CH2)6-NH2; Triantennary β-GalNAc 6-aminohexanoate; Tri-beta-GalNAc-6-ACA; Tris-GalNAc-Ahx-NH2; Tris-β-GalNAc-6-aminohexanoic acid; Tri-N-Acetyl-b-D-galactose glycodendrimer. Grades: ≥95%. CAS No. 1646198-77-7. Molecular formula: C67H121N11O28. Mole weight: 1528.75.
Tri-b-GalNAcAc3-C12-amido-C3-azide
Tri-b-GalNAcAc3-C12-amido-C3-azide is a multifunctional ligand designed for targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc cluster for high-affinity binding to ASGPR, a C12-amide linker for stability, and a terminal azide group that enables click chemistry reactions. This compound is widely used in the development of targeted drug delivery systems, including siRNA and small molecule therapies, as well as in the creation of imaging probes and protein degradation agents. Alternative Names: Tris-GalNAc-β-C12-azide (perac); Trebler GalNAc azide (peracetylated); 3-azidopropylamino-C12-tris-beta-GalNAc-peracetylated; 3-azidopropylamino-C12-tris-beta-GalNAc (perAc); 3-Azido-propylamino-C12-tris-β-GalNAc-PerAc. Grades: >95% by HPLC. CAS No. 2790424-72-3. Molecular formula: C94H154N14O38. Mole weight: 2088.30.
Tri-b-GalNAc-b-alanine-PEG3-amine
Tri-b-GalNAc-b-alanine-PEG3-amine is a versatile ligand designed for targeted drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features three terminal β-N-acetylgalactosamine (GalNAc) sugars that bind efficiently to ASGPR, a β-alanine linker, and a PEG3 spacer to enhance water solubility and influence pharmacokinetics. The terminal amine group serves as a reactive handle for conjugation to various biomolecules via amide bond formation. This compound is widely used in the development of targeted therapies and diagnostics, particularly for liver-related applications. Alternative Names: Tris-β-D-GalNAc-β-Ala-PEG3-NH2; Tris-β-GalNAc-β-Ala-PEG3-amine; Triantennary β-D-GalNAc-β-Ala-PEG3-NH2; Tri-β-D-GalNAc-β-Ala-PEG3-NH2; (β-D-GalNAc)3-β-Ala-PEG3-NH2; Tris(β-N-acetylgalactosamine)-β-alanine-triethylene glycol-amine; Tris-GalNAc-β-Ala-PEG3-NH2. Grades: >95% by HPLC. CAS No. 2924873-29-8. Molecular formula: C73H132N12O32. Mole weight: 1689.89.
Tri-b-GalNAc-b-alanine-PEG3-biotin
Tri-b-GalNAc-b-alanine-PEG3-biotin is a functionalized ligand designed for targeting the asialoglycoprotein receptor (ASGPR) on hepatocytes. It consists of a trivalent β-GalNAc cluster linked to a biotin tag via a β-alanine-PEG3 spacer. This structure enables efficient binding to ASGPR, facilitating the uptake of biotinylated molecules by liver cells. It is widely used in applications such as lysosomal targeting, hepatocyte studies, and targeted drug delivery. Alternative Names: Tri-GalNAc biotin; Triantennary GalNAc-β-Alanine-PEG3-Biotin; Tri-GalNAc-β-Ala-PEG3-Biotin; (β-GalNAc)3-sp-β-Ala-PEG3-Biotin; Tris-β-GalNAc-β-Ala-PEG3-biotin; Triantennary β-D-GalNAc-β-Alanine-PEG3-Biotin; Tris-GalNAc-β-Ala-PEG3-Biotin; Tris-GalNAc-β-Ala-PEG3-Biotin; (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-NH-Biotin. Grades: >95% by HPLC. CAS No. 3062597-46-7. Molecular formula: C83H146N14O34S. Mole weight: 1916.19.
Tri-b-GalNAc-b-alanine-PEG3-DBCO
Tri-b-GalNAc-b-alanine-PEG3-DBCO is a functionalized ligand designed for targeted delivery and protein degradation applications. It consists of a trivalent β-GalNAc cluster that binds specifically to the asialoglycoprotein receptor (ASGPR) on hepatocytes, linked to a DBCO (dibenzocyclooctyne) group via a β-alanine-PEG3 spacer. This structure allows for efficient targeting of liver cells and enables click chemistry reactions with azide-containing molecules, facilitating the development of lysosomal targeting chimeras (LYTACs) and other targeted therapies. Alternative Names: Tris-GalNAc-β-Ala-PEG3-DBCO; Trivalent GalNAc-β-Ala-PEG3-DBCO; (β-D-GalNAc-sp)3-NHC(O)-β-Ala-PEG3-DBCO; Tris-β-GalNAc-β-Alanine-PEG3-Dibenzocyclooctyne; Triantennary β-D-GalNAc triethyleneglycol Dibenzocyclooctyne. Grades: >95% by HPLC. Molecular formula: C92H145N13O34. Mole weight: 1977.20.
Tri-b-GalNAc-b-alanine-PEG3-FITC
Tri-b-GalNAc-b-alanine-PEG3-FITC is a functionalized ligand designed for targeting the asialoglycoprotein receptor (ASGPR) on hepatocytes. It features a trivalent β-GalNAc cluster linked to a FITC (fluorescein isothiocyanate) fluorophore via a β-alanine-PEG3 spacer. This structure enables efficient binding to ASGPR and allows for fluorescence labeling, making it useful for imaging studies and tracking the uptake of ligands by liver cells. Alternative Names: Tris-GalNAc-β-Ala-PEG3-FITC; Triantennary β-D-GalNAc-β-Alanine-PEG3-FITC; Tri-GalNAc-β-Ala-PEG3-FITC; (β-GalNAc-sp)3-β-Ala-PEG3-FITC; Tris-β-GalNAc-β-Ala-PEG3-fluorescein isothiocyanate. Grades: >95% by HPLC. Molecular formula: C94H143N13O37S. Mole weight: 2079.29.
Tri-b-GalNAc-b-alanine-PEG4-DBCO
Tris-GalNAc-β-Ala-PEG4-DBCO is a functionalized ligand designed for targeted delivery and click chemistry applications. It features a trivalent GalNAc cluster that binds specifically to the asialoglycoprotein receptor (ASGPR) on hepatocytes, linked to a DBCO (dibenzocyclooctyne) group via a β-alanine-PEG4 spacer. This structure enables efficient targeting of liver cells and facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. It is widely used in the development of lysosomal targeting chimeras (LYTACs) for protein degradation, siRNA delivery, and other targeted therapeutic applications. Alternative Names: Tris-GalNAc-β-Ala-PEG4-DBCO; Trivalent GalNAc-β-Ala-PEG4-DBCO; (β-D-GalNAc-sp)3-NHC(O)-β-Ala-PEG4-DBCO; Tris-β-GalNAc-β-Alanine-PEG4-Dibenzocyclooctyne; Triantennary β-D-GalNAc tetraethyleneglycol Dibenzocyclooctyne; Tris-β-GalNAc-β-Ala-PEG4-DBCO. Grades: >95% by HPLC. Molecular formula: C94H149N13O35. Mole weight: 2021.25.
Tri-b-GalNAc-C12-alkyne
Tri-b-GalNAc-C12-alkyne is a multivalent ligand designed for targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features three GalNAc units linked to a C12 alkyne chain, which provides high binding affinity to ASGPR on liver cells. This compound is widely used for conjugating therapeutic payloads such as siRNA to enable targeted gene silencing in the liver. The alkyne group also allows for further functionalization through click chemistry reactions. Alternative Names: Tris-β-GalNAc-C12-alkyne; Treble GalNAc Alkyne; Triantennary β-GalNAc alkyne; Tri-GalNAc beta alkyne; Tris-GalNAc-beta-C12-alkyne; Alkyne-C12-tris-β-GalNAc. Grades: >90% by HPLC. CAS No. 2641582-95-6. Molecular formula: C76H133N11O29. Mole weight: 1664.92.
Tri-b-GalNAc-C12-amido-C3-azide
Tri-b-GalNAc-C12-amido-C3-azide is a functionalized ligand designed for targeted drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). This compound features three terminal GalNAc units that specifically bind to ASGPR, a C12 amide linker for stability, and a C3-azide group that enables bioconjugation via click chemistry. The trivalent GalNAc cluster enhances the uptake of therapeutic payloads by hepatocytes, making it suitable for delivering siRNA, small molecules, or nanoparticles specifically to the liver. This targeted approach improves therapeutic efficacy while reducing off-target effects, making it a valuable tool in the development of liver-specific drug delivery systems. Alternative Names: Tris-β-GalNAc-C12-azide; Trebler GalNAc azide; Tris-GalNAc-C12-3-azidopropylamine; 3-Azidopropylamino-C12-tris-beta-GalNAc; 3-Azido-propylamino-C12-tris-β-GalNAc. Grades: >95% by HPLC. CAS No. 2757017-93-7. Molecular formula: C76H136N14O29. Mole weight: 1709.97.
Tri-b-GalNAc-gly-biotin
Tri-b-GalNAc-gly-biotin is a functionalized ligand designed for targeted drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc cluster linked to biotin through a glycine spacer, enabling efficient uptake by liver cells through ASGPR-mediated endocytosis. In drug delivery applications, Tri-b-GalNAc-gly-biotin can be used to conjugate therapeutic agents, such as siRNA or proteins, to facilitate their specific delivery to the liver. The biotin moiety can also bind to streptavidin or neutravidin, which can be further functionalized to carry drug payloads. This approach enhances the therapeutic efficacy of the drug while reducing off-target effects, making it a valuable tool for liver-targeted therapies. Alternative Names: Tris-β-GalNAc-Gly-biotin; Biotin-Gly-tris-beta-GalNAc; Trebler GalNAc Biotin; Tri-GalNAc-β-Gly-Biotin; Triantennary GalNAc beta glycine biotin; Biotin-Gly-tris-beta-GalNAc; Biotin-Gly-tris-β-GalNAc. Grades: >90% by HPLC. Molecular formula: C73H127N13O30S. Mole weight: 1698.93.
Tri-b-GalNAc-gly-C6-DBCO
Tri-b-GalNAc-gly-C6-DBCO is a functionalized ligand designed for targeted drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc cluster linked to a DBCO group through a glycine and C6 spacer, enabling efficient binding to ASGPR and facilitating click chemistry reactions with azide-containing molecules. This compound is widely used in applications such as targeted siRNA delivery, protein degradation via LYTACs, and the development of advanced drug delivery systems, enhancing therapeutic efficacy and specificity in liver-targeted therapies. Alternative Names: DBCO-Gly-tris-β-GalNAc; Tris-β-GalNAc-Gly-DBCO; Trebler GalNAc DBCO; DBCO-Gly-tris-beta-GalNAc. Grades: >95% by HPLC. Molecular formula: C84H130N12O30. Mole weight: 1787.99.
Tri-b-GalNAc-PEG5-sulfo-NHS ester
Tri-b-GalNAc-PEG5-sulfo-NHS ester is a versatile targeting ligand designed for efficient drug delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc cluster for high-affinity binding to ASGPR, a PEG5 spacer for enhanced stability and solubility, and a sulfo-NHS ester group that enables conjugation to biomolecules containing primary amines. This compound is widely used in the development of targeted therapies, including lysosome-targeting chimeras (LYTACs) for protein degradation and RNA delivery, facilitating efficient uptake and therapeutic efficacy in liver cells. Alternative Names: Tris-GalNAc-PEG5-sulfo-NHS Ester; (β-D-GalNAc)3-PEG5-sulfo-NHS Ester; (β-D-GalNAc-sp)3-NHC(O)-PEG5-sulfo-NHS Ester; Triantennary β-D-GalNAc pentaethyleneglycol (PEG5) carboxylic acid N-hydroxysulfosuccinimide ester. Grades: >95%. CAS No. 3008204-27-8. Molecular formula: C79H137N11O40S. Mole weight: 1913.05.
Trichloroethyl 2,3,4-tri-O-acetyl-b-D-glucopyranosiduronic acid methyl ester, a paramount constituent renowned in the realm of biomedical research concerning pharmacological advancement and ailment intervention. Its remarkable anti-inflammatory capabilities have engrossed considerable scientific attention, paving the way for its investigation in combatting inflammatory afflictions and their associated maladies. Alternative Names: 2,2,2-Trichloroethyl b-D-glucopyranosiduronic acid methyl ester triacetate. CAS No. 59495-75-9. Molecular formula: C15H19Cl3O10. Mole weight: 465.66.
Trichloroethyl b-D-glucuronide
Trichloroethyl b-D-glucuronide, a compound of great scientific significance, is a vital urinary biomarker employed in the study of chemical exposure, particularly to trichloroethylene. Its invaluable function extends to biomedicine, where it is utilized to examine the interplay between glucuronidation and drug metabolism and elimination. This multifaceted compound promises to continue revolutionizing the field of chemical and biomedical research. Alternative Names: 2,2,2-Trichloroethyl β-D-glucopyranosiduronic acid; Glucopyranosiduronic acid, 2,2,2-trichloroethyl, β-D-; 2,2,2-Trichloroethanol glucuronide; Trichloroethanol glucuronide; Urochloralic acid; β,β,β-Trichloroethyl-β-D-glucuronic acid; β,β,β-Trichloroethyl-β-D-glucuronide. CAS No. 97-25-6. Molecular formula: C8H11Cl3O7. Mole weight: 325.53.
Triclosan-beta-D-glucopyranoside
Triclosan-beta-D-glucopyranoside is a compound used for studying bacterial infections and skin diseases. It exhibits antibacterial properties similar to triclosan while possessing enhanced stability and decreased toxicity. With potent antimicrobial activity, it proves effective in studying various drug-resistant pathogens. Alternative Names: 5-Chloro-2-(2,4-dichlorophenoxy)phenyl β-D-glucopyranoside; (2S,3R,4S,5S,6R)-2-(5-chloro-2-(2,4-dichlorophenoxy)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 302925-51-5. Molecular formula: C18H17Cl3O7. Mole weight: 451.68.
Tridecyl b-D-maltopyranoside
Tridecyl b-D-maltopyranoside is a crucial component in the biomedical industry. This product finds application in drug delivery systems and is commonly used as a surfactant for solubilizing and stabilizing various pharmaceutical compounds. It has proven efficacy in improving the bioavailability and delivery of drugs. Alternative Names: n-Triadecyl-b-D-maltoside; Tridecyl 4-O-a-D-glucopyranosyl-b-D-glucopyranoside; Tridecyl 4-O-α-D-glucopyranosyl-β-D-glucopyranoside; n-Tridecyl β-D-maltopyranoside; Tridecyl β-D-maltopyranoside; Tridecyl β-D-maltoside; Tridecylmaltoside. CAS No. 93911-12-7. Molecular formula: C25H48O11. Mole weight: 524.64.
Triethyl-a-cyclodextrin
Triethyl-a-cyclodextrin is a remarkable biomedical compound, proving exceedingly essential as a proficient solubilizing protagonist and efficacious drug delivery mechanism. This remarkable compound, endowed with exceptional encapsulative potential, substantially heightens drug durability and bioaccessibility, thereby becoming an invaluable compound in the therapeutic research of sundry afflictions. Alternative Names: Hexakis-(2,3,6-tri-O-ethyl)-a-cyclodextrin; Hexakis(2,3,6-tri-O-ethyl)-α-cyclodextrin; 2A,2B,2C,2D,2E,2F,3A,3B,3C,3D,3E,3F,6A,6B,6C,6D,6E,6F-Octadeca-O-ethyl-α-cyclodextrin. CAS No. 145454-97-3. Molecular formula: C72H132O30. Mole weight: 1477.80.
Trifluoroacetamidopropyl b-D-galactopyranoside
Trifluoroacetamidopropyl b-D-galactopyranoside is a renowned chemical compound extensively employed in the biomedical sector, serving for studying carbohydrate-protein interactions, particularly for maladies associated with carbohydrate metabolism.
Trifucosyl(1-2,1-2,1-3)-iso-lacto-N-octaose is a critically important compound in the therapeutic research of select ailments and conditions. Operating as an indispensable active constituent, it exhibits a precise mechanism to selectively target specific pharmaceutical drugs or pathological states. Alternative Names: TFiLNO(1-2, 1-2, 1-3); O-6-Deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→3)]-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)]-O-β-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 141342-93-0. Molecular formula: C72H121N3O53. Mole weight: 1876.72.
Trifucosyllacto-N-hexaose
Trifucosyllacto-N-hexaose is an extraordinary compound originating from the esteemed lactose. It demonstrates remarkable immunomodulatory attributes, capable of studying manifestations of autoimmune afflictions. Alternative Names: TFLNH; Trifucosyllacto-N-Hexaose a; O-6-Deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-[6-deoxy-α-L-galactopyranosyl-(1→4)]-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→3)-O-[β-D-galactopyranosyl-(1→4)]-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-D-glucose; TF-LNH; Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)[Fuc(a1-3)[Gal(b1-4)]GlcNAc(b1-6)]Gal(b1-4)aldehydo-Glc. Grades: 95%. CAS No. 116883-09-1. Molecular formula: C58H98N2O43. Mole weight: 1511.39.
Trifucosyllacto-N-neotetraose I
Trifucosyllacto-N-neotetraose I is an advanced and innovative compound with multifaceted applications, specifically tailored to study a range of debilitating disorders like cancer, autoimmune ailments and infectious maladies. Alternative Names: TFLNnT I; Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)[Fuc(a1-3)]Gal(b1-4)[Fuc(a1-2)]aldehydo-Glc. Molecular formula: C44H75NO33. Mole weight: 1146.05.
Trifucosyl-p-lacto-N-hexaose, a burgeoning contender in cancer therapy, showcases multifaceted potential as a profound inhibitor of galectin-3. A notorious instigator of cancer cell proliferation and subversive evasion of the immune system. Moreover, its efficacious ability in awakening robust immunological reactions against cancer cells insinuates the possibility of being the next big immunotherapy drug. Its intricate composition and inscrutable mode of operation demand critical assessment. Alternative Names: TFpLNH; α-Fuc-(1→2)-β-Gal-(1→3)-[α-Fuc-(1→4)]-β-GlcNAc-(1→3)-β-Gal-(1→4)-[α-Fuc-(1→3)]-β-GlcNAc-(1→3)-β-Gal-(1→4)-Glc; Leb-Lex-L nonasaccharide; Trifucosyl-para-lacto-N-hexaose I; Fuc-a-1,2-Gal-b-1,3(Fuc-a-1,4)GlcNAc-b-1,3-Gal-b-1,4(Fuc-a-1,3)GlcNAc-b-1,3-Gal-b-1,4-Glc; D-Glucose, O-6-deoxy-α-L-galactopyranosyl-(1→3)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→4)-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-β. Grades: ≥90%. CAS No. 120864-60-0. Molecular formula: C58H98N2O43. Mole weight: 1511.39.
Trigalacturonic acid
Trigalacturonic acid is a vital substance used in the biomedicine industry. It exhibits potential therapeutic effects in treating various diseases like cancer and inflammatory disorders. Extensive research has shown its ability to target and inhibit tumor growth, making it an intriguing candidate for anticancer therapies. Alternative Names: Gal-a-1,4-Gal-a-1,4-GalA; O-α-D-Galactopyranuronosyl-(1→4)-O-α-D-galactopyranuronosyl-(1→4)-D-galacturonic acid; alpha-Gala-gala-gala. CAS No. 6037-45-2. Molecular formula: C18H26O19. Mole weight: 546.39.
Tri-GalNAc-C5-amine
Tri-GalNAc-C5-amine is a functionalized ligand designed for targeting the asialoglycoprotein receptor (ASGPR) on hepatocytes. It features three GalNAc units linked to an alkyl C5 chain and terminated with an amine group, which serves as a reactive handle for further conjugation. This compound is widely used in lysosome-targeting chimera (LYTAC) research and development. Upon binding to ASGPR, Tri-GalNAc conjugates are efficiently internalized via receptor-mediated endocytosis, enabling targeted delivery of therapeutic cargos such as RNA or Cas9 complexes to hepatocytes. It can also be labeled with dyes for tissue imaging applications. Alternative Names: Tri-b-GalNAc-triazolyl-C5-amine; Triantennary β-D-GalNAc pentamine; Triantennary β-D-GalNAc amine; Tri-beta-GalNAc-amine; Tris-β-GalNAc-C5-amine; N-[2-[[1-[2-[2-[2-[2-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]-1,1-bis[[[1-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]methyl]ethyl]-6-aminohexanamide. Grades: ≥90% by HPLC. CAS No. 2098275-86-4. Molecular formula: C67H118N14O31. Mole weight: 1615.73.
TriGalNAc CBz
TriGalNAc CBz is a chemically modified derivative of GalNAc (N-acetylgalactosamine) designed to serve as a ligand for the Asialoglycoprotein Receptor (ASGPR). This receptor is highly expressed in hepatocytes and plays a crucial role in the endocytosis of glycoproteins. TriGalNAc CBz leverages this mechanism to facilitate targeted drug delivery, particularly in the context of mRNA therapeutics and lysosome-targeting chimeras (LYTACs). By binding to ASGPR, it enhances the cellular uptake and intracellular delivery of therapeutic agents, improving their efficiency and specificity. Due to its unique targeting properties, TriGalNAc CBz has become an important tool in biomedical research, especially for developing advanced drug delivery systems and novel protein degradation strategies. Alternative Names: 5-[[2-(Acetylamino)-3,4,6-tri-O-benzoyl-2-deoxy-β-D-galactopyranosyl]oxy]pentanoic acid; 5-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-bis(benzoyloxy)-6-((benzoyloxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid. Grades: >98%. CAS No. 186613-57-0. Molecular formula: C34H35NO11. Mole weight: 633.65.
Tri-GalNAc(OAc)3
Tri-GalNAc(OAc)3 is a modified glycosylated compound that features three N-acetylgalactosamine (GalNAc) units, and is typically provided as a trifluoroacetic acid (TFA) salt. This structure enhances the compound's solubility and stability, making it suitable for use in various biological applications, including drug delivery and targeted therapeutics. The presence of multiple acetyl groups can improve the bioavailability and cellular uptake of the compound, while the tri-GalNAc configuration allows for specific interactions with receptors, particularly in the context of glycoengineering and the development of therapies for conditions like cancer and genetic disorders. It is a molecular building block belonging to the GalNAc series or related delivery systems. Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. Alternative Names: Peracetylated GalNAc-L96-Amine; Peracetylated tri-GalNAc-amine; 6-Amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy. Grades: ≥95%. CAS No. 1159408-64-6. Molecular formula: C79H128N10O36. Mole weight: 1793.91.
Tri-GalNAc(OAc)3-COOH
Tri-GalNAc-COOH is a glycosylated compound that consists of three N-acetylgalactosamine (GalNAc) units linked together, with a carboxylic acid (COOH) functional group at one end. This structure enhances the compound's ability to interact with specific receptors and pathways in biological systems, making it particularly useful in the development of targeted therapeutics, such as in drug delivery and antibody-drug conjugates. The presence of multiple GalNAc residues can facilitate increased binding affinity to proteins, such as those involved in cell signaling, thus enhancing the efficacy of therapeutic agents in applications related to cancer and other diseases where targeted treatment is essential. It is a molecular building block belonging to the GalNAc series or related delivery systems. Alternative Names: tri-GalNAc-COOH (acetylation); 36-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-21,21-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid. Grades: ≥95%. CAS No. 3008204-26-7. Molecular formula: C93H152N10O44. Mole weight: 2114.27.
Tri-GalNAc(OAc)3 formate salt
Tri-GalNAc(OAc)3 formate salt is a functionalized ligand designed for targeted drug delivery and protein degradation applications. It consists of three GalNAc units, each acetylated to enhance stability and solubility, and is typically used as a precursor for synthesizing GalNAc-based LYTACs (lysosome-targeting chimeras). These LYTACs leverage the asialoglycoprotein receptor (ASGPR) to deliver and degrade target proteins in hepatocytes. The formate salt form of this compound ensures better solubility in aqueous solutions, facilitating its use in biological and chemical applications. Alternative Names: Tri-β-GalNAc-amine formate; Triantennary GalNAc-NH2 formate Salt (peracetate); Tri-GalNAc-NH2 formate (peracetate); GalNAc-NH2 formate Salt (peracetate); Tris-GalNAc-NH2 formate Salt (peracetate); Tris-β-GalNAc-amine formate salt (peracetate); Trimeric GalNAc-NH2 formate Salt (peracetate); Peracetylated GalNAc-L96-Amine formate salt; Peracetylated tri-GalNAc-amine formate salt; 6-Amino-11,17-dioxo. Grades: >95%. Molecular formula: C79H129N10O36.CHO2. Mole weight: 1839.93.
Tri-guluronic acid sodium salt
Tri-guluronic acid sodium salt is an extraordinary biomedical compound, used for developing precise drug delivery mechanisms. Remarkably, it exhibits profound affinity towards targeted receptors, thereby assuming a prized position in the research of anti-cancer, cardiovascular and anti-inflammatory pharmaceutical concoctions. Alternative Names: L-Triguluronic acid trisodium salt; O-α-L-Gulopyranuronosyl-(1→4)-O-α-L-gulopyranuronosyl-(1→4)-α-L-gulopyranuronic acid trisodium salt. Molecular formula: C18H23O19Na3. Mole weight: 612.33.