BOC Sciences 8 - Products

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.

Product
Brevinin-2-RA21 antimicrobial peptide Brevinin-2-RA21 antimicrobial peptide was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA22 antimicrobial peptide Brevinin-2-RA22 antimicrobial peptide was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA3 peptide precursor Brevinin-2-RA3 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA4 peptide precursor Brevinin-2-RA4 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA5 peptide precursor Brevinin-2-RA5 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA6 antimicrobial peptide Brevinin-2-RA6 antimicrobial peptide was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. Grades: >97% by HPLC. BOC Sciences 8
Brevinin-2-RA6 peptide precursor Brevinin-2-RA6 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2-RA7 peptide precursor Brevinin-2-RA7 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. Grades: >96% by HPLC. BOC Sciences 8
Brevinin-2-RA8 peptide precursor Brevinin-2-RA8 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. Grades: >97% by HPLC. BOC Sciences 8
Brevinin-2-RA9 peptide precursor Brevinin-2-RA9 peptide precursor was found in Odorrana andersonii (golden crossband frog). It has antimicrobial activity. BOC Sciences 8
Brevinin-2Rb Brevinin-2Rb was found in Rana ridibunda. It has antimicrobial activity. BOC Sciences 8
Brevinin-2Rc Brevinin-2Rc has antimicrobial activity. The source of Brevinin-2Rc is Rana ridibunda. Grades: >97% by HPLC. BOC Sciences 8
Brevinin-2Rd Brevinin-2Rd has antimicrobial activity. The source of Brevinin-2Rd is Rana ridibunda. BOC Sciences 8
Brevinin-2-related peptide Brevinin-2-related peptide is first isolated from skin secretions of the mink frog Lithobates septentrionalis. Brevinin-2-related peptide shows broad-spectrum antimicrobial activity but its therapeutic potential is limited by moderate hemolytic activity. Alternative Names: B2RP. BOC Sciences 8
Brevinin-2-RN1 Brevinin-2-RN1 has antibacterial and antifungal activity. Brevinin-2-RN1 was found in Rana nigrovittata. Grades: >96% by HPLC. BOC Sciences 8
Brevinin-2-RN2 Brevinin-2-RN2 has antibacterial and antifungal activity. Brevinin-2-RN2 was found in Rana nigrovittata. BOC Sciences 8
Brevinin-2RTa Brevinin-2RTa is active against S. aureus ATCC2592, R. rhodochrous (Gram-poistive) and P. faecalis X29 (Gram-negative). Brevinin-2RTa was found in Amolops ricketti. Grades: >97% by HPLC. BOC Sciences 8
Brevinin-2RTb Brevinin-2RTb was found in Amolops ricketti. It has antibacterial activity. BOC Sciences 8
Brevinin-2SHa antimicrobial peptide Brevinin-2SHa antimicrobial peptide was found in Odorrana schmackeri. It has antimicrobial activity. BOC Sciences 8
Brevinin-2SKa Brevinin-2SKa was found in Rana sakuraii. It has antimicrobial activity. BOC Sciences 8
Brevinin-2SKb The source of Brevinin-2SKb is Rana sakuraii. It is active against E. coli (MIC=3 uM). Grades: >95% by HPLC. BOC Sciences 8
Brevinin-2SN1 The source of Brevinin-2SN1 is Hylarana spinulosa. It is active against some Gram-negative and a variety of Gram-positive bacterial strains. Brevinin-2SN1 is also active against fungus C.glabrata 090902 but not against C.albicans. It shows hemolytic activity against human erythrocytes. BOC Sciences 8
Brevinin-2SN2 The source of Brevinin-2SN2 is Hylarana spinulosa. It is active against some Gram-negative and a variety of Gram-positive bacterial strains. Brevinin-2SN2 is also active against fungus C.glabrata 090902 but not against C.albicans. It shows hemolytic activity against human erythrocytes. BOC Sciences 8
Brevinin-2SN2_2 antimicrobial peptide precursor Brevinin-2SN2_2 antimicrobial peptide precursor is isolated from Hylarana spinulosa. It has antimicrobial activity. BOC Sciences 8
Brevinin-2SN3 The source of Brevinin-2SN3 is Hylarana spinulosa. It is active against some Gram-negative and a variety of Gram-positive bacterial strains. Brevinin-2SN3 is also active against fungus C.glabrata 090902 but not against C.albicans. It shows hemolytic activity against human erythrocytes. Grades: >97% by HPLC. BOC Sciences 8
Brevinin-2SN4 The source of Brevinin-2SN4 is Hylarana spinulosa. Brevinin-2SN4 is active against a variety of Gram-negative and Gram-positive bacterial strains. It is not active against fungi. Brevinin-2SN4 also shows very weak hemolytic activity against human erythrocytes. BOC Sciences 8
Brevinin-2SN4 antimicrobial peptide precursor Brevinin-2SN4 antimicrobial peptide precursor is isolated from Hylarana spinulosa. It has antimicrobial activity. BOC Sciences 8
Brevinin 2Ta Brevinin 2Ta is produced by Rana temporaria. B-2Ta exhibited remarkable antimicrobial and anticancer activities. BOC Sciences 8
Brevinin-2Tb Brevinin-2Tb was found in Rana temporaria. It is an antimicrobial peptide. BOC Sciences 8
Brevinin-2Tc Brevinin-2Tc was found in Rana temporaria. It contains one disulfide bond: 23, 29. Brevinin-2TC has antibacterial activity against representative Gram-negative and Gram-positive bacteria. Molecular formula: C150H242N40O36S2. Mole weight: 3245.89. BOC Sciences 8
Brevinin-2Td Brevinin-2Td was found in Rana temporaria. It has antibacterial activity against representative Gram-negative and Gram-positive bacteria. BOC Sciences 8
Brevinin-2TP1_2 antimicrobial peptide precursor Brevinin-2TP1_2 antimicrobial peptide precursor was originally isolated from Hylarana taipehensis. BOC Sciences 8
Brevinin-2TP1 antimicrobial peptide precursor Brevinin-2TP1 antimicrobial peptide precursor was found in Hylarana taipehensis. BOC Sciences 8
Brevinin-2TR1_2 antimicrobial peptide precursor Brevinin-2TR1_2 antimicrobial peptide precursor was originally isolated from Amolops torrentis. BOC Sciences 8
Brevinin-2TR2 antimicrobial peptide precursor Brevinin-2TR2 antimicrobial peptide precursor was originally isolated from Amolops torrentis. BOC Sciences 8
Brevinin-2TSa Brevinin-2TSa was found in Rana tsushimensis. Brevinin-2TSa has broad-spectrum growth inhibitory activity against a range of Gram-negative and Gram-positive bacteria (including methicillin-resistant S. aureus MRSA) (MIC< or=25 uM) and relatively low hemolytic activity against human erythrocytes (LD50=100 uM). Grades:>96% by HPLC. Molecular formula: C148H253N41O41S3. Mole weight: 3359.03. BOC Sciences 8
Brochocin C Brochocin C, produced by Brochothrix campestris, is active against many strains of the closely related meat spoilage organism Brochothrix thermosphacta and a wide range of other gram-positive bacteria, including spores of Clostridium botulinum. BOC Sciences 8
Bromoacetyl resin Bromoacetyl resin can be selectively cleaved by trimethyltin hydroxide to phenacyl ester of BOC-amino acids and -peptides attached to polystyrene resins using a highly efficient non-acidolytic method. Alternative Names: Br-CH2-CO-Ph-polymer. BOC Sciences 8
Bromoethyl resin Bromoethyl resin. Alternative Names: Br-Et-Resin; Polystyrene A Br. BOC Sciences 8
Bromo-tris-pyrrolidinophosphoniumhexafluorophosphate A stable reagent for the coupling of N-Methylamino acids in peptide synthesis. Alternative Names: PyBroP; Bromotripyrrolidinophosphonium hexafluorophosphate; bromotri(1-pyrrolidinyl)phosphonium hexafluorophosphate; (T-4)-Bromotri-1-pyrrolidinyl-phosphorus(1+) Hexafluorophosphate(1-); Pyrrolidine Phosphorus Complex; Bromotris(pyrrolidino)phosphonium Hexafluorophosphate. Grades: ≥ 99% (HPLC). CAS No. 132705-51-2. Molecular formula: C12H24N3P2BrF6. Mole weight: 466.18. BOC Sciences 8
BrOP BrOP. Alternative Names: BroP Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate; Bromotris(dimethylamino)phosphonium hexafluorophosphate; ; BROP; BROMO-TRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE (BROP); BROP BROMOTRIS(DIMETHYLAMINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; ACMC-20aljt. Grades: 98% (HPLC). CAS No. 50296-37-2. Molecular formula: C6H18BrF6N3P2. Mole weight: 388.07. BOC Sciences 8
BTD-1 BTD-1 is produced by Papio anubis. BTD-1 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. BTD-2 is more effective against E.coli than BTD-1. BOC Sciences 8
BTD-2 BTD-2 is produced by Papio anubis. BTD-2 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. BTD-2 is more effective against E.coli than BTD-1. BOC Sciences 8
BTD-4 BTD-4 is produced by Papio anubis. It has antibacterial and antifungal activity. BOC Sciences 8
BTD-7 BTD-7 is produced by Papio anubis. BTD-7 has antimicrobial activity against the Gram-negative bacterium E.coli ML35, the Gram-positive bacterium S.aureus 502a, and the fungus C.albicans 16820. BOC Sciences 8
BTFFH BTFFH. Alternative Names: 1-(Fluoro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate; Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium Hexafluorophosphate; Fluoro-dipyrrolidinocarbenium hexafluorophosphate; Pyrrolidinium,1-(fluoro-1-pyrrolidinylmethylene)-,hexafluorophosphate(1-); Bis(tetramethylene fluoroformamidinium hexafluorophosphate; Fluoro-dipyrrolidinocarbenium hexafluorophosphate. Grades: 98% (HPLC). CAS No. 164298-25-3. Molecular formula: C9H16F7N2P. Mole weight: 316.20. BOC Sciences 8
BTL BTL was isolated from Bacillus subtilis B-TL2. BTL shows relatively low identity to other antimicrobial peptides from bacteria. The peptide exhibited strong inhibitory activity against mycelial growth of Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata. BOC Sciences 8
Buforin-1 The source of Buforin-1 is Bufo gargarizans. Buforin I is generated from histone H2A by pepsin-directed proteolysis in the cytoplasm of gastric gland cells. After secretion into the gastric lumen, buforin I remains adhered to the mucous biofilm that lines the stomach, thus providing a protective antimicrobial coat. Buforins also are known to possess anti-endotoxin and anticancer activities, thus making these peptides attractive reagents for pharmaceutical applications. BOC Sciences 8
Buforin-EC Buforin-EC was found in Euphlyctis cyanophlyctis. It has antibacterial activity against E.coli HP101BA (MIC=9.6 μM), K.pneumoniae PTCC1388 (MIC=10.6 μM), M.luteus PTCC1625 (MIC=6.0 μM) and S.aureus PTCC1431 (MIC=8.1 μM). Buforin-EC has no or very limited (<3%) hemolytic activity at concentrations of 15 μg/ml and 60 μg/ml, respectively. BOC Sciences 8
Buforin I Buforin I is a 39-amino acid AMP that was first isolated from the stomach tissue of the Asian toad Bufo gargarizans. Compared with other amphibian AMPs, such as magainin 2, buforin I shows much stronger antimicrobial activities in vitro against a broad spectrum of microorganisms. Buforins have anti-endotoxin and anticancer activities. Alternative Names: H-Ala-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-Gly-Asn-Tyr-OH; L-alanyl-glycyl-L-arginyl-glycyl-L-lysyl-L-glutaminyl-glycyl-glycyl-L-lysyl-L-valyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanyl-glycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valyl-glycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-glycyl-L-asparagyl-L-tyrosine. Grades: ≥90% by HPLC. CAS No. 173010-28-1. Molecular formula: C184H318N70O47. Mole weight: 4262.93. BOC Sciences 8
Buforin II It is a 21 amino acid peptide derived from Buforin I peptide that is isolated from the Asian toad Bufo gargarizans. It has anti-microbial activity by penetrating bacteria and inhibiting cellular functions. Compared with magainin 2, It binds DNA and RNA from E.coli with a much greater affinity. It is also considered to be a cell-delivery peptide and has been shown to deliver SiRNAs into cells followed by effective mRNA degradation. Alternative Names: H-Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys-OH; Buforin; L-Threonyl-L-arginyl-L-seryl-L-seryl-L-arginyl-L-alanylglycyl-L-leucyl-L-glutaminyl-L-phenylalanyl-L-prolyl-L-valylglycyl-L-arginyl-L-valyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-arginyl-L-lysine; Buforin 2. Grades: ≥95%. CAS No. 172998-24-2. Molecular formula: C106H184N40O26. Mole weight: 2434.88. BOC Sciences 8
Butanoic acid,3-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-4- Butanoic acid,3-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-4-. CAS No. 2350701-37-8. Molecular formula: C19H18FNO4. Mole weight: 343.3. BOC Sciences 8
Buthinin Buthinin was found in Androctonus australis. It is active against both Gram-positive and Gram-negative bacteria. BOC Sciences 8
Butyl L-alaninate Butyl L-alaninate. Alternative Names: (S)-Butyl 2-aminopropanoate; L-Alanine, butyl ester; L-Ala-Onbu. CAS No. 2885-2-1. Molecular formula: C7H15NO2. Mole weight: 145.20. BOC Sciences 8
Butyrivibriocin AR10 Butyrivibriocin AR10 is a new cyclic bacteriocin produced by the ruminal anaerobe Butyrivibrio fibrisolvens AR10. BOC Sciences 8
Butyrolacton-BCP-COOH Butyrolacton-BCP-COOH. Alternative Names: 3-(5-oxotetrahydrofuran-2-yl)bicyclo[1.1.1]pentane-1-carboxylic acid; 3-Butyrolacton-BCP-1-carboxylic acid. Molecular formula: C10H12O4. Mole weight: 196.20. BOC Sciences 8
BV6 BV-6 is a selective inhibitor of apoptosis (IAP) family with IC50 value of 7.2 μM when tested with H460 cells. It acts by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. BV-6 induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 μM. In BALB/c mice model with transplanted abdominal cavities from donor mouse uterine tissue, intraperitoneally with BV-6 repressed the advancement of endometriosis, cell proliferative activity via inhibiting the expression of IAPs. In hematological THP-1 cells, pre-treatment with BV-6 increased the CIK cells killing ability and the same results were achieved in solid malignancy RH30 cells. Grades: ≥98%. CAS No. 1001600-56-1. Molecular formula: C70H96N10O8. Mole weight: 1205.57. BOC Sciences 8
BVD 10 BVD 10 is a selective NPY Y1 receptor antagonist (Ki = 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors, respectively) with no activity at Y4 receptors. Alternative Names: BVD 10; BVD10; BVD-10. Grades: >98%. CAS No. 262418-00-8. Molecular formula: C58H92N16O13. Mole weight: 1221.46. BOC Sciences 8
Bz-Ala-Arg-OH Bz-Ala-Arg-OH. Alternative Names: Benzoylalanylarginine; N-Benzoyl-Ala-Arg-OH; L-Arginine, N(2)-(N-benzoyl-L-alanyl)-. Grades: 95%. CAS No. 71448-11-8. Molecular formula: C16H23N5O4. Mole weight: 349.38. BOC Sciences 8
Bz-Arg-4-Abz-OH HCl Bz-Arg-4-Abz-OH HCl. Alternative Names: Nα-Benzoyl-L-arginine 4-carboxyanilide hydrochloride; Bz-Arg-4-Abz-OH Hydrochloride. Grades: ≥ 98% by TLC. Molecular formula: C20H23N5O4.HCl. Mole weight: 433.89. BOC Sciences 8
Bz-Arg-4-Abz-OH·HCl Bz-Arg-4-Abz-OH·HCl. Alternative Names: Na-Benzoyl-L-arginine 4-carboxyanilide hydrochloride. CAS No. 60833-82-1. Molecular formula: C20H23N5O4. Mole weight: 397.43. BOC Sciences 8
Bz-Arg-Gly-Phe-Phe-Leu-4MbetaNA A substrate for cathepsin D. Alternative Names: benzoyl-Arg-Gly-Phe-Phe-Leu-MNA; Bz-Arg-Gly-Phe-Phe-Leu-4-methoxy-beta-naphthylamide; Bz-RGFFL-MNA. CAS No. 99112-24-0. Molecular formula: C50H59N9O7. Mole weight: 898.06. BOC Sciences 8
Bz-Arg-Gly-Phe-Phe-Pro-4MβNA HCl Bz-Arg-Gly-Phe-Phe-Pro-4MβNA HCl. Alternative Names: Bz-Arg-Gly-Phe-Phe-Pro-4MbNA HCl; Bz-RGFFP-MNA HCl. CAS No. 201928-98-5. Molecular formula: C49H56ClN9O7. Mole weight: 918.49. BOC Sciences 8
Bz-Arg-His-D-Asp-CH2Cl Bz-Arg-His-D-Asp-CH2Cl is a peptide inhibitor of D-Aspartyl Endopeptidase. Alternative Names: Bz-RHd-CMK; (Benzoyl-L-arginyl-L-histidyl-D-aspart-1-yl)chloromethane. CAS No. 468102-94-5. Molecular formula: C24H31N8O6Cl. Mole weight: 563.01. BOC Sciences 8
Bz-Cit-OMe HCl Bz-Cit-OMe HCl. Grades: ≥ 95%. Molecular formula: C14H19N3O4·HCl. Mole weight: 329.8. BOC Sciences 8
Bz-Gly-Gly-OH Bz-Gly-Gly-OH. Alternative Names: Hippuryl glycine(N-Benzoylglycyl)glycine. Grades: ≥ 98% (HPLC). CAS No. 1145-32-0. Molecular formula: C11H12N2O4. Mole weight: 236.23. BOC Sciences 8
Bz-Gly-His-Leu hydrate N-Hippuryl-His-Leu (hydrate) can be used for the identification of ACE inhibitors in vitro. Alternative Names: N-Hippuryl-His-Leu hydrate; N-benzoylglycyl-L-histidyl-L-leucine, hydrate; N-Benzoyl-Gly-His-Leu. Grades: 95%. CAS No. 207386-83-2. Molecular formula: C21H27N5O5.xH2O. Mole weight: 447.5 (anhydrous). BOC Sciences 8
BZ-ILE-GLU-GLY-ARG-PNA Bz-IEGR-pNA is a substrate for plasma kallikrein and coagulation factor XIIa. Alternative Names: Nalpha-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide; L-Argininamide, N-benzoyl-L-isoleucyl-L-alpha-glutamylglycyl-N-(4-nitrophenyl)-. CAS No. 59068-47-2. Molecular formula: C32H43N9O9. Mole weight: 697.74. BOC Sciences 8
Bz-Nle-Lys-Arg-Arg-AMC Bz-Nle-Lys-Arg-Arg-AMC is a substrate of dengue virus NS2B-NS3 and yellow fever virus NS3 protease. Alternative Names: BZ-NLE-LYS-ARG-ARG-AMC. CAS No. 863975-32-0. Molecular formula: C41H60N12O7. Mole weight: 832.99. BOC Sciences 8
BzO-BCP-NH-Boc BzO-BCP-NH-Boc. Alternative Names: 3-(t-butoxycarbonylamino)bicyclo[1.1.1]pentan-1-yl benzoate. Molecular formula: C17H21NO4. Mole weight: 303.36. BOC Sciences 8

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