BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tazarotenic Acid | Tazarotenic acid is an active metobolite of Tazarotene and could be used in the treatment of photodamaged skin. Synonyms: AGN 190299; AGN-190299; AGN190299; 6-((4,4-Dimethylthiochroman-6-yl)ethynyl)nicotinic acid. Grades: >98%. CAS No. 118292-41-4. Molecular formula: C19H17NO2S. Mole weight: 323.41. |  |
| Tazarotenic Acid Methyl Ester | Tazarotenic Acid Methyl Ester is a related compound of Tazarotene, which is a third-generation prescription topical retinoid used to treat plaque psoriasis, acne, photoaged and photodamaged skin. Synonyms: 6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-Pyridinecarboxylic Acid Methyl Ester; Methyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate; Tazarotene Impurity 9; 3-Pyridinecarboxylic acid, 6-[2-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-, methyl ester; Methyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate. Grades: ≥95%. CAS No. 1332579-70-0. Molecular formula: C20H19NO2S. Mole weight: 337.43. | |
| TBA-354 | TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA-824. TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. TBA-354 is 5 to 10 times more potent than PA-824, but selected mutants are cross-resistant to PA-824 and delamanid. TBA-354 is 2 to 4 times more potent than PA-824 when combined with bedaquiline, and when administered at a dose equivalent to that of PA-824, TBA-354 demonstrated superior sterilizing efficacy. TBA-354 has high bioavailability and a long elimination half-life. In vitro studies suggest a low risk of drug-drug interactions. Low-dose aerosol infection models of acute and chronic murine tuberculosis reveal time- and dose-dependent in vivo bactericidal activity that is at least as potent as that of delamanid and more potent than that of PA-824. Synonyms: TBA-354, TBA 354, TBA354, SN31354, SN-31354, SN 31354. Grades: >98%. CAS No. 1257426-19-9. Molecular formula: C19H15F3N4O5. Mole weight: 436.34. | |
| TBAJ-876 | A potent anti-tuberculosis agent via inhibiting the mycobacterial F-ATP synthase. Synonyms: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol. Grades: 98%. CAS No. 2332841-25-3. Molecular formula: C31H37BrN4O7. Mole weight: 657.55. | |
| t-butyl 4-chloroacetoacetate | t-butyl 4-chloroacetoacetate is a derivative of Penicillin. Penicillin belongs to the β-lactam class of antibiotics, is a very common antibacterial drug. Synonyms: tert-Butyl 4-chloro-3-oxobutyrate; tert-Butyl 4-chloroacetoacetate; Butanoic acid, 4-chloro-3-oxo-, 1,1-dimethylethyl ester; t-butyl 4-chloro-3-oxobutanoate; 4-Chloro-3-oxobutyric acid tert-butyl ester. Grades: 95%. CAS No. 74530-56-6. Molecular formula: C8H13ClO3. Mole weight: 192.64. | |
| t-Butyldimethylsilyl 6,7-O-Isopropylidenepseudomonic Acid A | t-Butyldimethylsilyl 6,7-O-Isopropylidenepseudomonic Acid A is an impurity of Mupirocin, which is a t-RNA synthetase inhibitor used in the treatment of bacterial skin infections. Synonyms: 9-({(2E)-4-[(3aS,4S,7S,7aR)-7-({(2S,3S)-3-[(2R,3S)-3-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-butanyl]-2-oxiranyl}methyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl]-3-methyl-2-butenoyl}oxy)nonanoic acid; 9-(((E)-4-((3aS,4S,7S,7aR)-7-(((2S,3S)-3-((2R,3S)-3-((tert-Butyldimethylsilyl)oxy)butan-2-yl)oxiran-2-yl)methyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-4-yl)-3-methylbut-2-enoyl)oxy)nonanoic Acid. Molecular formula: C35H62O9Si. Mole weight: 654.94. | |
| T.cruzi Inhibitor | T.cruzi Inhibitor is a novel inhibitor of Trypanosoma cruzi. Synonyms: N-Benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide. CAS No. 1350920-22-7. Molecular formula: C22H25F3N2O. Mole weight: 390.45. | |
| TC-S 7001 | TC-S 7001 is a potent and highly selective ROCK inhibitor. Its IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively. It exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. It reduces blood pressure in normotensive and hypertensive rats. Synonyms: TC-S 7001; TC S 7001; TCS 7001; TC-S-7001; TCS7001; Azaindole-1; Azaindole 1; 6-Chloro-N4-{3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl}pyrimidine-2,4-diamine;Rho Kinase Inhibitor;ROCK inhibitor;ROCK. Grades: >98 %. CAS No. 867017-68-3. Molecular formula: C18H13ClF2N6O. Mole weight: 402.79. | |
| Tebipenem | Tebipenem is a broad-spectrum orally administered antibiotic that exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin. Synonyms: LJC11036; LJC 11036; LJC-11036. Grades: >98%. CAS No. 161715-21-5. Molecular formula: C16H21N3O4S2. Mole weight: 383.49. | |
| Tedizolid | Torezolid is a novel oxazolidinone for gram-positive infections. It was a reversible inhibitor of human MAO-A and MAO-B. Uses: Anti-bacterial agents. Synonyms: TR-700; TR 700; TR700; DA-7157; DA7157; DA 7157; Tedizolid; Torezolid. trade name Sivextro. Grades: >98%. CAS No. 856866-72-3. Molecular formula: C17H15FN6O3. Mole weight: 370.34. | |
| Tedizolid Phosphate | Torezolid phosphate is a novel oxazolidinone for gram-positive infections, with IC50 of 8.7 μM and 5.7 μM for monoamine oxidase (MAO)-A and MAO-B, respectively. It is commonly used for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by several Gram-positive bacteria. Uses: The treatment of acute bacterial skin and skin structure infections (absssi). Synonyms: TR-701FA; Torezolid phosphate; Sivextro; Tedizolid (phosphate); UNII-O7DRJ6R4DW. Grades: >98%. CAS No. 856867-55-5. Molecular formula: C17H16FN6O6P. Mole weight: 450.32. | |
| Teduglutide | Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue that made of 33 amino acid. Teduglutide differs from GLP-2 by an amino acid (an alanine is replaced with a glycine). Teduglutide is superior to GLP-2 on its longer acting. It was approved by FDA named Gattex® on December 21, 2012 as an orphan drug for the treatment of short bowel syndrome (SBS). Uses: A glucagon-like peptide-2 (glp-2) analogue for the treatment of short bowel syndrome(sbs). Synonyms: Teduglutide; Gattex; (Gly2)GLP-2; ALX-0600; Gly(2)-GLP-2; ALX 0600; ALX0600. Grades: 98%. CAS No. 197922-42-2. Molecular formula: C164H252N44O55S. Mole weight: 3752.07. | |
| Teicoplanin | Teichomycin is a glycopeptide antibiotic produced by Actinoplanes teichomyceticus nov. sp. (ATTCC 31121). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: Targocid; Teichomycin; Teichomycin A2; Teicoplanin. Grades: Assay: 900 IU/mg (anhydrous and sodium-free substance). CAS No. 61036-62-2. Molecular formula: C88H97Cl2N9O33. Mole weight: 1879.65. | |
| Telaprevir | Telaprevir is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it demonstrated excellent antiviral activity both in genotype 1b HCV replicon cells (50% inhibitory concentration [IC50] = 354 nM) and in human fetal hepatocytes infected with genotype 1a HCV-positive patient sera (IC50 = 280 nM). Telaprevir forms a covalent but reversible complex with the genotype 1a HCV NS3-4A protease in a slow-on, slow-off process with a steady-state inhibition constant (K(I)*) of 7 nM. Dissociation of the covalent enzyme-inhibitor complex of Telaprevir and genotype 1a HCV protease has a half-life of almost an hour. A >4-log10 reduction in the HCV RNA levels was observed after a 2-week incubation of replicon cells with Telaprevir, with no rebound of viral RNA observed after withdrawal of the inhibitor. In several animal species, Telaprevir exhibits a favorable pharmacokinetic profile with high exposure in the liver. In a recently developed HCV protease mouse model, Telaprevir showed excellent inhibition of HCV NS3-4A protease activity in the liver. Uses: Oligopeptides. Synonyms: Telavic; VRT 111950; VX 950; Incivek; Incivo; LY 570310; MP 424; S-Telaprevir; (1S, 3aR, 6aS) - (2S) -2-Cyclohexyl-N- (2-pyrazinylcarbonyl) glycyl-3-methyl-L-valyl-N- [ (1S) -1- [2- (cyclopropylamino) -2-oxoacetyl]butyl]octahydrocyclopenta [c]pyrrole-1-carboxamide. Grades: ≥98% (HPLC). CAS No. 402957-28-2. Molecular formula: C36H53N7O6. Mole weight: 679.85. | |
| Telotristat Etiprate | Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Uses: Combination therapy of somatostatin analogue (ssa) and telotristat ethyl. Synonyms: LX 1606 Hippurate; LX1606 Hippurate; LX-1606 Hippurate; Telotristat ethyl hippurate; (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate 2-benzamidoacetate. Grades: >98%. CAS No. 1137608-69-5. Molecular formula: C36H35ClF3N7O6. Mole weight: 754.15. | |
| Temocapril HCl | Temocapril HCl is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: CS-622 HCl; CS 622 HCl; CS622 HCl. Grades: >98%. CAS No. 110221-44-8. Molecular formula: C23H28N2O5S2.HCl. Mole weight: 513.07. | |
| Temocillin disodium salt | Temocillin disodium salt is the salt of Temocillin. Temocillin is a β-lactamase-resistant penicillin that is effective against Gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; (6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt; Temocillin sodium; temocillin disodium. Grades: ≥90%. CAS No. 61545-06-0. Molecular formula: C16H18N2Na2O7S2. Mole weight: 458.42. | |
| Temoporfin | Temoporfin, also known as m-THPC or KW-2345, is a synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size. Synonyms: Foscan; m-THPC; KW-2345; KW2345; KW 2345. Grades: >90%. CAS No. 122341-38-2. Molecular formula: C44H32N4O4. Mole weight: 680.75. | |
| Temozolomide Cyano Impurity | One impurity of Temozolomide, which is an imidazotetrazine derivative and has been found to be a DNA methylating agent and could be used as an antineoplastic. Synonyms: 8-Descarboxamido-8-cyano Temozolomide; 3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carbonitrile; Cyanotemozolomide; 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonitrile. Grades: > 95%. CAS No. 114601-31-9. Molecular formula: C6H4N6O. Mole weight: 176.14. | |
| Tenapanor | This active molecular is an sodium-proton exchanger NHE3 inhibitor under the development of Ardelyx. This antiporter protein plays a really important role in sodium handling in the gastrointestinal tract and kidney and it regulates the levels of sodium absorbed and secreted by the body. Therefore, tenapanor can be useful in the treatment of chronic kidney disease and hypertension because both of them are exacerbated by excess sodium in the diet. In Oct 2016, Phase-III clinical trials in Hyperphosphataemia (in patients with end-stage renal disease) in USA was on going. Uses: Hyperphosphataemia. Synonyms: 3- ( (S) -6, 8-dichloro-2-methyl-1, 2, 3, 4-tetrahydroisoquinolin-4-yl) -N- (26- ( (3- ( (S) -6, 8-dichloro-2-methyl-1, 2, 3, 4-tetrahydroisoquinolin-4-yl) phenyl) sulfonamido) -10, 17-dioxo-3, 6, 21, 24-tetraoxa-9, 11, 16, 18-tetraazahexacosyl) benzenesulfonamide; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor free base. Grades: 98%. CAS No. 1234423-95-0. Molecular formula: C50H66Cl4N8O10S2. Mole weight: 1145.04. | |
| Tenapanor HCl | Tenapanor, also known as AZD-1722 and RDX 5791, is a first-in-class, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger NHE3. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor acts in the gastrointestinal tract to reduce the absorption of sodium and phosphate, with minimal systemic drug exposure. Synonyms: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor; Tenapanor hydrochloride; Tenapanor dihydrochloride. CAS No. 1234365-97-9. Molecular formula: C50H68Cl6N8O10S2. Mole weight: 1217.9. | |
| Tenofovir Alafenamide | Tenofovir Alafenamide is a prodrug of Tenofovir, which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral. Synonyms: (S)-isopropyl 2- ( ( (S) - ( ( ( (R) -1- (6-amino-9H-purin-9-yl) propan-2-yl) oxy) methyl) (phenoxy) phosphoryl) amino) propanoate; GS7340; GS-7340; GS 7340; Tenofovir alafenamide. Grades: >98%. CAS No. 379270-37-8. Molecular formula: C21H29N6O5P. Mole weight: 476.47. | |
| Tenofovir alafenamide hemifumarate | Tenofovir alafenamide hemifumarate, also known as Tenofovir alafenamide fumarate (2:1), is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevents HIV from multiplying and can reduce the amount of HIV in the body. Synonyms: Isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate hemifumarate; TAF; GS734; GS-734; GS 734; GS 7340; GS-7340; GS7340; Tenofovir alafenamide fumarate (2:1). Grades: > 98%. CAS No. 1392275-56-7. Molecular formula: C46H62N12O14P2. Mole weight: 1069.02. | |
| Tenofovir Alafenamide PMPA Impurity | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: Tenofovir Dimer; Bis((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)diphosphonic Acid. CAS No. 1607007-18-0. Molecular formula: C18H26N10O7P2. Mole weight: 556.41. | |
| Tenofovir Disoproxil Fumarate | Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate. Synonyms: GS-1278 Disoproxil Fumarate; GS 1278 Disoproxil Fumarate; GS1278 Disoproxil Fumarate. Grades: >98%. CAS No. 202138-50-9. Molecular formula: C19H30N5O10P.C4H4O4. Mole weight: 635.51. | |
| Tenofovir Disoproxil Isopropoxycarbonyl | Cas No. 1244022-54-5. | |
| Tenofovir Disoproxil Related Compound E | Cas No. 211364-69-1. | |
| Tenofovir Impurity E | Cas No. 1244022-56-7. | |
| Tenofovir Mono POC Dimer | Cas No. 1962114-92-6. | |
| Tenofovir Related Compound 1 | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: 9-[ (2R) -2- (diphenoxyphosphorylmethoxy) propyl]purin-6-amine. Grades: > 95%. CAS No. 342631-41-8. Molecular formula: C21H22N5O4P. Mole weight: 439.41. | |
| Tenofovir Related Compound 2 | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: (R)-Phenyl hydrogen (((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate. Grades: > 95%. CAS No. 379270-35-6. Molecular formula: C15H18N5O4P. Mole weight: 363.32. | |
| Tepotinib | Tepotinib, also known as EMD 1214063 and MSC2156119, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. Tepotinib selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kinase MET (also known as hepatocyte growth factor receptor or HGFR), is the product of the proto-oncogene c-Met and is overexpressed or mutated in many tumor cell types. This protein plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis. Synonyms: EMD-1214063; EMD1214063; EMD 1214063; MSC-2156119; MSC2156119; MSC-2156119. CAS No. 1100598-32-0. Molecular formula: C29H28N6O2. Mole weight: 492.583. | |
| Terazosin EP Impurity E | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Uses: An impurity of selective alpha 1 antagonists: terazosin (t105000) and prazosin (p702325). Synonyms: 1,4-Bis(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine; 2,2'-(Piperazine-1,4-diyl)bis(6,7-dimethoxyquinazolin-4-amine). CAS No. 102839-00-9. Molecular formula: C24H28N8O4. Mole weight: 492.53. | |
| Terazosin EP Impurity O | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Synonyms: Terazosin Impurity 17. Grades: 95%. CAS No. 547730-06-3. Molecular formula: C14H22N2O4. Mole weight: 282.33. | |
| Terazosin EP Impurity O-RR | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Synonyms: Terazosin impurity 11-RR. Grades: 95%. Molecular formula: C14H22N2O4. Mole weight: 282.33. | |
| Terazosin Related Compound A | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergicblocker. Synonyms: N-Des((tetrahydrofuran-2-yl)methanone)) Terazosin Dihydrochloride; 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine Dihydrochloride. Grades: > 95%. CAS No. 60548-08-5. Molecular formula: C14H19N5O2. 2HCl. Mole weight: 362.25. | |
| Terazosin Related Compound C | An impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic receptor blocker. Synonyms: Terazosin Dimer Impurity Dihydrochloride; 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] Dihydrochloride. Grades: > 95%. CAS No. 1486464-41-8. Molecular formula: C24H28N8O4. 2HCl. Mole weight: 565.45. | |
| Terbutaline Impurity 007 | One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Molecular formula: C8H10O4. Mole weight: 170.16. | |
| Terbutaline Impurity 008 | One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Molecular formula: C22H22O4. Mole weight: 350.41. | |
| Terbutaline Impurity 010 | One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Molecular formula: C19H25NO3. Mole weight: 315.41. | |
| Terbutaline Impurity 22 | One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Synonyms: Terbutaline-011. Grades: 95%. CAS No. 1226543-90-3. Molecular formula: C22H20O4. Mole weight: 348.4. | |
| Terbutaline Impurity 6 hydrobromide | One impurity of Terbutaline, which is a β-Adrenergic receptor agonist and could be used as a bronchodilator agent. Grades: 95%. CAS No. 28924-20-1. Molecular formula: C26H30NO3Br. Mole weight: 484.42. | |
| Terconazole | Terconazole is an antifungal drug used to treat vaginal yeast infection. It has a relatively broad spectrum compared to azole compounds. It may exert its antifungal activity by disrupting normal fungal cell membrane permeability. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis. It has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. It may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans. It was developed by Johnson & Johnson and has been listed. Uses: Terconazole is an antifungal drug used to treat vaginal yeast infection. it may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of candida albicans. Synonyms: Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, cis-; cis-1-(p-{[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine; Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-; rel-1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)piperazine; (±)-Terconazole; Fungistat; Gyno-Terazol; NSC 331942; R 42470; Terazol; Tercospor; Termayazole; Triaconazole. Grades: 98%. CAS No. 67915-31-5. Molecular formula: C26H31Cl2N5O3. Mole weight: 532.46. | |
| Teriparatide Dimer | Teriparatide Dimer is an impurity of Teriparatide, which is an anabolic osteoporosis drug used to treat osteoporosis. Synonyms: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH; L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanyl-L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparagyl-L-leucyl-glycyl-L-lysyl-L-histidyl-L-leucyl-L-asparagyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparagyl-L-phenylalanine. Molecular formula: C362H580N110O101S4. Mole weight: 8217.53. | |
| Terlipressin | Terlipressin is an analog of vasopressin and a partial agonist of the vasopressin V1A receptor (Ki = 0.85 μM). It has been used as a vasoactive drug in the management of low blood pressure. Uses: Vasoconstrictor agents. Synonyms: glipressin; glycylpressin; glypressin; Remestyp; terlypressin; TGLVP; triglycylvasopressin; triglycyl lysine vasopressin; Terlipressine; Terlipressinum; Terlipressina; Terlipressina; EINECS 238-680-8; LS-161411. Grades: ≥95%. CAS No. 14636-12-5. Molecular formula: C52H74N16O15S2. Mole weight: 1227.4. | |
| Terlipressin Diacetate Salt | Terlipressin is an analog of vasopressin and a partial agonist of the vasopressin V1A receptor (Ki = 0.85 μM). It has been used as a vasoactive drug in the management of low blood pressure. Synonyms: 1-Triglycyl-8-lysine Vasopressin Diacetate Salt; Glycylpressin Diacetate Salt; Glypressin Diacetate Salt; Nα-Gly-Gly-Gly-8-Lys-vasopressin Diacetate Salt; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin Diacetate Salt; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin Diacetate Salt; Nα-Glycylglycylglycyl-vasopressin Diacetate Salt; Remestyp Diacetate Salt; Triglycyl-8-lysine-vasopressin Diacetate Salt; [N-α-Triglycyl-8-lysine]-vasopressin Diacetate Salt. Grades: ≥95%. CAS No. 1884420-36-3. Molecular formula: C56H82N16O19S2. Mole weight: 1347.47. | |
| tert-butyl(((1R,3aR,7aR)-1-((2R,5S,E)-5,6-dimethyl-6-((tetrahydro-2H-pyran-2-yl)oxy)hept-3-en-2-yl)-7a-methyloctahydro-1H-inden-4-yl)oxy)dimethylsil | It is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: Paricalcitol Impurity A001. Grades: >95%. CAS No. 1407097-26-0. Molecular formula: C30H56O3Si. Mole weight: 492.85. | |
| tert-butyl 2-((4R,6R)-6-(2-(1-(2-((4R,6R)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)ethyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(2-(1-(2-((4R,6R)-6-(2-(tert-butoxy)-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)ethyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1229658-18-7. Molecular formula: C48H67FN2O9. Mole weight: 835.07. | |
| tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 2-Methyl-2-propanyl {(4R,6R)-6-[2-({[(4R,6R)-6-{2-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetyl}amino)ethyl]-2,2-dimethyl-1,3-d ioxan-4-yl}acetate; 1,1-Dimethylethyl (4R,6R)-6-[2-[[2-[(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetyl]amino]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 1116118-82-1. Molecular formula: C50H64FN3O8. Mole weight: 854.06. | |
| tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(2-(2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2299304-89-3. Molecular formula: C24H44N2O7. Mole weight: 472.62. | |
| tert-butyl 2-((4R,6R)-6-(2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 1371615-55-2. Molecular formula: C47H60FN3O8. Mole weight: 814.01. | |
| tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate; (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-Dimethylethyl Ester, (4R-cis)-. CAS No. 125971-94-0. Molecular formula: C14H23NO4. Mole weight: 269.34. | |
| tert-butyl 2-((4R,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2088732-01-6. Molecular formula: C14H27NO4. Mole weight: 273.37. | |
| tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate | tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate; 2,4-Dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonic Acid 1,1-Dimethylethyl Ester; (4R,6S)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 2-[(4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. | |
| tert-butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Synonyms: 1260939-66-9; tert-butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylatetert-butyl4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate; STL084881ZINC57523146. Grades: 95%. CAS No. 1260939-66-9. Molecular formula: C19H27N5O4. Mole weight: 389.45. | |
| Tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 4-[6-[6-(1-butoxy-vinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino]-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester. CAS No. 866084-31-3. Molecular formula: C33H45N7O4. Mole weight: 603.768. | |
| tert-butyl 4-(6-((8-cyclopentyl-5-methyl-7-oxo-6-vinyl-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Grades: 95%. CAS No. 1941177-45-2. Molecular formula: C29H37N7O3. Mole weight: 531.65. | |
| tert-butyl 4-(6-((8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate | An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. CAS No. 571189-65-6. Molecular formula: C27H35N7O3. Mole weight: 505.61. | |
| Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Palbociclib Impurity K; 4-(6-Amino-3-pyridyl)-1-Boc-piperazine; 1-Boc-4-(6-amino-3-pyridyl)piperazine. Grades: 97%. CAS No. 571188-59-5. Molecular formula: C14H22N4O2. Mole weight: 278.35. | |
| tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate | tert-butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-Cyclopropanoylpiperazine-1-carboxylic Acid tert-Butyl Ester. CAS No. 414910-15-9. Molecular formula: C13H22N2O3. Mole weight: 254.33. | |
| tert-Butyl (6-(3-Cyanoguanidino)hexyl)carbamate | tert-Butyl (6-(3-Cyanoguanidino)hexyl)carbamate is an intermediate for the synthesis of Chlorhexidine, which is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: 2-Methyl-2-propanyl [6- (N'-cyanocarbamimidamido) hexyl]carbamate; Carbamic acid, N-[6-[[ (cyanoamino)iminomethyl]amino]hexyl]-, 1,1-dimethylethyl ester. Molecular formula: C13H25N5O2. Mole weight: 283.37. | |
| tert-Butyl (6- (3- (N- (4-Chlorophenyl) carbamimidoyl) guanidino) hexyl) carbamate | tert-Butyl (6- (3- (N- (4-Chlorophenyl) carbamimidoyl) guanidino) hexyl) carbamate is an intermediate for the synthesis of Chlorhexidine, which is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: 2-Methyl-2-propanyl (6-{N'-[N- (4-chlorophenyl) carbamimidoyl]carbamimidamido}hexyl) carbamate; Carbamic acid, N- [6- [ [ [ [ [ (4-chlorophenyl) amino] iminomethyl] amino] iminomethyl] amino] hexyl] -, 1,1-dimethylethyl ester. Molecular formula: C19H31ClN6O2. Mole weight: 410.94. | |
| tert-butyl (R)-piperidin-3-ylcarbamate | Cas No. 309956-78-3. | |
| tert-butyl (S)-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: (S)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate; Linagliptin Impurity E. CAS No. 668273-75-3. Molecular formula: C30H36N8O4. Mole weight: 572.66. | |
| Tertiapin | Tertiapin is a 21-amino acid peptide isolated from the venom of the honey bee (Apis mellifera). It was shown to block inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK). Synonyms: H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; L-Alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-methionyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-L-lysinamide; Tertiapin (reduced). Grades: ≥95% by HPLC. CAS No. 58694-52-3. Molecular formula: C106H180N34O23S5. Mole weight: 2459.14. | |
| Tetrabutylammonium thiocyanate | Synonyms: tetrabutylammonium rhodanide; tetra-n-butylammonium thiocyanate. Grades: >95.0%(T). CAS No. 3674-54-2. Molecular formula: C16H36N.CNS. Mole weight: 300.55. | |
| Tetracaine Impurity C | One impurity of Tetracaine, which could be used in the studies of spinal anesthesia. Synonyms: Methyl 4-(butylamino)benzoate. Grades: > 95%. CAS No. 71839-12-8. Molecular formula: C12H17NO2. Mole weight: 207.27. | |
| Tetracaine N-Oxide | One impurity of Tetracaine, which could be used in the studies of spinal anesthesia. Synonyms: Tetracaine N-Oxide; TetracaineN-Oxide; 55750-02-2; CID 11185111; 2-[4-(butylamino)benzoyl]oxy-N,N-dimethylethanamine oxide; CHEBI:185882; 2-((4-(Butylamino)benzoyl)oxy)-N,N-dimethylethan-1-amine oxide. Grades: > 95%. CAS No. 55750-02-2. Molecular formula: C15H24N2O3. Mole weight: 280.37. | |
| Tetracosactide | Tetracosactide is a fragment of adrenocorticotrophic hormone (ACTH), a tropic hormone produced by the anterior pituitary. In veterinary medicine, tetracosactide is used to diagnose adrenal diseases in dogs, horses, and cats. Synonyms: Cosyntropin; Tetracosactrin; α1-24-Corticotropin; ACTH (1-24); ACTH (1-24), human; Adrenocorticotropic hormone human fragment 1-24; Adrenocorticotropic hormone (human, 1-24); H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline. Grades: 98%. CAS No. 16960-16-0. Molecular formula: C136H210N40O31S. Mole weight: 2933.46. | |
| Tetrahydro-11-deoxy Cortisol | Tetrahydro-11-deoxy Cortisol is a metabolite of Cortisol. Synonyms: (3α,5β)-3,17,21-Trihydroxypregnan-20-one; 5β-Pregnane-3α,17α,21-triol-20-one; 11-Deoxytetrahydrocortisol; 3α,17,21-Trihydroxy-5β-pregnan-20-one; Tetrahydro S; Tetrahydro-11-deoxy-17α-hydroxycorticosterone; Tetrahydro-11-deoxycortisol; THS; Tetrahydro-11-d. Grades: > 95%. CAS No. 68-60-0. Molecular formula: C21H34O4. Mole weight: 350.49. | |
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