BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Anacardic Acid | Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition. Alternative Names: 6-Pentadecylsalicylic acid; Hydroginkgolic acid; 6-(Pentadecyl)Salicylic Acid. Grades: >98%. CAS No. 16611-84-0. Molecular formula: C22H36O3. Mole weight: 348.52. |  |
| Anagrelide-[13C3] | Anagrelide-[13C3] is the labelled analogue of Anagrelide, which is a phosphodiesterase inhibitor with antiplatelet activity. It is a medication used for the treatment of essential thrombocytosis (ET). Alternative Names: Anagrelide 13C3; 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one-13C3; BL-4162A-13C3; BMY-26538-01-13C3; Agrylin-13C3; Tromboreductin-13C3; Xagrid-13C3. Grades: 98%; ≥99% atom 13C. CAS No. 1219531-58-4. Molecular formula: C7[13C]3H7Cl2N3O. Mole weight: 259.06. | |
| (-)-Anatabine | (-)-Anatabine is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Alternative Names: 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2S)-; (2S)-1,2,3,6-Tetrahydro-2,3'-bipyridine; 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (S)-; Anatabine; (S)-(-)-Anatabine; (S)-Anatabine; Anatabine, (-)-; (S)-1,2,3,6-Tetrahydro-2,3'-bipyridine. Grades: ≥95%. CAS No. 581-49-7. Molecular formula: C10H12N2. Mole weight: 160.22. | |
| (±)-Anatabine | (±)-Anatabine is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Alternative Names: 2,3'-Bipyridine, 1,2,3,6-tetrahydro-; (+/-)-1,2,3,6-Tetrahydro-2,3'-bipyridine; (+/-)-Anatabine; 1,2,3,6-Tetrahydro-2,3'-bipyridine; 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (±)-; (RS)-Anatabine; (±)-1,2,3,6-Tetrahydro-2,3'-bipyridine; 1,2,3,6-Tetrahydro-2,3'-dipyridine. Grades: ≥95%. CAS No. 2743-90-0. Molecular formula: C10H12N2. Mole weight: 160.22. | |
| (+/-)-Anatoxin A | (+/-)-Anatoxin A. Alternative Names: (+/-)-Anatoxin A; (+/-)-Anatoxin A fumarate. Grades: >96 %. CAS No. 64285-06-9. Molecular formula: C10H15NO.C4H4O4. Mole weight: 165.26. | |
| (±)-Anatoxin A fumarate | (±)-Anatoxin A fumarate is a secondary, bicyclic amine alkaloid isolated from the blue-green alga A. aquae. It has cyanotoxin with acute neurotoxicity and could cause loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis. It displays high affinity for nicotinic acetylcholine receptors with Kd value of 0.1-0.2 μM. It binds to α4β2- and α7-type nicotinic receptors with Ki values of 1.3 nM and 1.8 μM, respectively. It stimulates [3H]-dopamine release from striatal synaptosomes with an EC50 value of 134 nM. Alternative Names: (±)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate; rac-Anatoxin A Fumarate; 1-(9-Azabicyclo[4.2.1]non-2-en-2-yl)ethanone 2-Butenedioate. Grades: ≥96% by HPLC. CAS No. 1219922-30-1. Molecular formula: C14H19NO5. Mole weight: 281.31. | |
| (-)-ANATOXIN-A FUMARATE ((-)-ANTX-A FUMA RATE) | (-)-ANATOXIN-A FUMARATE ((-)-ANTX-A FUMA RATE). Grades: 95%. CAS No. 92142-32-0. Molecular formula: C10H15NO. Mole weight: 165.23200. | |
| (+)-ANATOXIN A HYDROCHLORIDE | (+)-ANATOXIN A HYDROCHLORIDE. Alternative Names: (1r)-1-(9-azabicyclo(4.2.1)non-2-en-2-yl)ethanonehydrochloride; 1-(9-azabicyclo(4.2.1)non-2-en-2-yl)-,hydrochloride,(1r)-ethanon; (+)-ANATOXIN A HYDROCHLORIDE; 2-ACETYL-9-AZABICYCLO[4.2.1]NON-2-ENE HYDROCHLORIDE; Ethanone, 1-(1R,6R)-9-azabicyclo4.2.1non-2-en. Grades: 95%. CAS No. 64314-16-5. Molecular formula: C10H16ClNO. Mole weight: 201.69. | |
| Andrographolide | Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. It has the effects of dispelling heat, detoxification, anti-inflammatory and relieving pain. Uses: Anticancer. Alternative Names: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methyle ne-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxy-2-oxolanone. Grades: >98%. CAS No. 5508-58-7. Molecular formula: C20H30O5. Mole weight: 350.45. | |
| Anemoside B4 | Anemoside B4 is extracted from the herb of Pulsatilla chinensis (Bge.) Regel. It inhibited the secretion of IL-10. Alternative Names: Chinensioside A; Pulchinenoside C; Pulsatilla saponin B4. Grades: >98%. CAS No. 129741-57-7. Molecular formula: C59H96O26. Mole weight: 1221.4. | |
| Anetumab-MMAE | Anetumab-MMAE is an antibody-drug conjugate consisting of an anti-MSLN monoclonal antibody and monomethyl auristatin E (MMAE). MMAE is an antimitotic agent that inhibits tubulin polymerization. | |
| Anetumab ravtansine | Anetumab ravtansine is an antibody-drug conjugate consisting of an anti-MSLN monoclonal antibody and the maytansinoid tubulin inhibitor DM4. Anetumab ravtansine has the potential for the treatment of patients with mesothelin-expressing tumors. Alternative Names: BAY 94-9343. CAS No. 1375258-01-7. | |
| Angelica oil | Extractives and their physically modified derivatives. Angelica archangelica, Umbelliferae. Angelica root oil; Angelica seed oil. Alternative Names: Oils, angelica; Angelica archangelica oil; Angelica seed oil; Oil of angelica. CAS No. 8015-64-3. | |
| Angiopep-2 | A Kunitz-derived inhibitor. Alternative Names: H-Thr-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-Lys-Arg-Asn-Asn-Phe-Lys-Thr-Glu-Glu-Tyr-OH. Grades: >95%. CAS No. 906480-05-5. Molecular formula: C104H149N29O31. Mole weight: 2301.47. | |
| Angiotensin I human acetate salt hydrate | Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II. Alternative Names: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.CH3CO2H.H2O. Grades: 98%. CAS No. 70937-97-2. Molecular formula: C64H95N17O17. Mole weight: 1374.54. | |
| Angiotensin II (5-8), human | Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Alternative Names: Angiotensin (5-8); H-IHPF-OH; L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Angiotensin II (5-8) (human, rat, mouse). Grades: ≥95%. CAS No. 34233-50-6. Molecular formula: C26H36N6O5. Mole weight: 512.60. | |
| Angiotensin I/II (1-7) | Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor, inducing vasorelaxation through release of NO and prostaglandins. Uses: Endogenous peptide fragment. Alternative Names: Angiotensin II (1-7) heptapeptide; TXA127; TXA 127; TXA127; Angiotensin i (1-7); therapeutic angiotensin(17)H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH. Grades: ≥90%. CAS No. 51833-78-4. Molecular formula: C41H62N12O11. Mole weight: 899. | |
| Angiotensin III (human, mouse) | Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II. Alternative Names: H-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; Ang III; Angiotensin III; 5-Ile-angiotensin III; 1-Desaspartyl-5-isoleucine angiotensin II; Des-asp(1)-(Ile(5))-angiotensin II; N5-(Diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; 2-8-angiotensin II, 5-L-isoleucine-. Grades: ≥95%. CAS No. 13602-53-4. Molecular formula: C46H66N12O9. Mole weight: 931.09. | |
| Anhydrosecoisolariciresinol | Anhydrosecoisolariciresinol is isolated from the flowers of Wedelia biflora. Anhydrosecoisolariciresinol can significantly decrease the growth of human breast cancer MCF-7 and MDA-MB-231 cell lines at 50 and 100 microM. Alternative Names: Shonanin; 3,4-Divanillyltetrahydrofuran. Grades: 98.0%. CAS No. 29388-33-8. Molecular formula: C20H24O5. Mole weight: 344.4. | |
| Anhydrotetracycline hydrochloride | Anhydrotetracycline acts as an inducer of tetracycline resistance genes by binding to and inactivating the tetracycline repressor TetR to allow expression of downstream genes of the tetr promoter. However, anhydrotetracycline binds to the TetR repressor with higher affinity without toxic effects. Anhydrotetracycline poorly binds the 30S ribosomal subunit, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than 1,000-fold above the dose that alters transcription through TetR. Alternative Names: (4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-tetracenecarboxamide hydrochloride (1:1). Grades: ≥98%. CAS No. 13803-65-1. Molecular formula: C22H22N2O7.HCl. Mole weight: 462.88. | |
| Anidulafungin | Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component, and thus is used as an antifungal drug. Alternative Names: Eraxis; Ecalta; LY303366; 1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-echinocandin B. Grades: >98%. CAS No. 166663-25-8. Molecular formula: C58H73N7O17. Mole weight: 1140.24. | |
| Aniline-[13C6] | Aniline-[13C6]. Alternative Names: 13C Labeled aniline; Aminobenzene-13C6; Benzeneamine-13C6; Phenylamine-13C6; Aniline-13C6. Grades: 99% by CP; 99% atom 13C. CAS No. 100849-37-4. Molecular formula: [13C]6H5NH2. Mole weight: 99.08. | |
| Aniline-[2,3,4,5,6-d5] | Aniline-[2,3,4,5,6-d5]. Alternative Names: Aniline-2,3,4,5,6-d5; Benzen-d5-amine; Benzen-2,3,4,5,6-d5-amine; Phenyl-d5 amine. Grades: 99% by CP; 98% atom D. CAS No. 4165-61-1. Molecular formula: C6H2D5N. Mole weight: 98.16. | |
| Anisole-[2,3,4,5,6-d5] | Anisole-[2,3,4,5,6-d5]. Alternative Names: Methoxy(benzene-d5); Anisole-2,3,4,5,6-d5. Grades: 99% by CP; 98% atom D. CAS No. 50629-14-6. Molecular formula: C7H3D5O. Mole weight: 113.17. | |
| Anisomycin | It is produced by the strain of Streptomyces griseolus. It inhibits protein synthesis. it has anti-fungal, anti-fine bacteria, anti-tumor and antigenic insect action. Alternative Names: Flagecidin; NSC-76712; AI3-50846; NSC76712; AI350846; NSC 76712; AI3 50846. Grades: ≥98%. CAS No. 22862-76-6. Molecular formula: C14H19NO4. Mole weight: 265.30. | |
| Annonacin | Annonacin is a natural lipophilic mitochondrial complex I inhibitor found in the herbs of Annona glabra. Annonacin has cytotoxicity and may have anti-cancer activity. Uses: Anti-cancer. Alternative Names: (5S)-5-Methyl-3-[(2R,8R,13R)-2,8,13-trihydroxy-13-[[(2R)-tetrahydro-5α-[(R)-1-hydroxytridecyl]furan]-2β-yl]tridecyl]-2(5H)-furanone. Grades: 95%. CAS No. 111035-65-5. Molecular formula: C35H64O7. Mole weight: 596.89. | |
| (-)-Anonaine | (-)-Anonaine is an aporphine alkaloid found in Xylopia emarginata and Annona purpurea with anti-cancer, trypanocidal and antiplasmodial activites. Alternative Names: (R)-6,7,7a,8-Tetrahydro-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; [7aR,(-)]-6,7,7a,8-Tetrahydro-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-, (7aR)-; Anonain; Anonaine; (7aR)-6,7,7a,8-Tetrahydro-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (R)-Annonaine; 1,2-(Methylenedioxy)-6aβ-noraporphine. Grades: ≥95%. CAS No. 1862-41-5. Molecular formula: C17H15NO2. Mole weight: 265.31. | |
| Anoplin | Anoplin is an antimicrobial peptide produced by Anoplius samariensis (Solitary wasp). It has antibacterial activity against both Gram-positive and Gram-negative bacteria. Alternative Names: Gly-Leu-Leu-Lys-Arg-Ile-Lys-Thr-Leu-Leu-NH2; glycyl-L-leucyl-L-leucyl-L-lysyl-L-arginyl-L-isoleucyl-L-lysyl-L-threonyl-L-leucyl-L-leucinamide; Glycyl-L-leucyl-L-leucyl-L-lysyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-L-lysyl-L-threonyl-L-leucyl-L-leucinamide. Grades: 97%. CAS No. 321352-67-4. Molecular formula: C54H104N16O11. Mole weight: 1153.50. | |
| Ansamitocin derivative TN-006 | Ansamitocin derivative TN-006 is a derivative of Ansamitocin, a family of polyketide antibiotics comprising a naphthalene / benzene or napthaquinone / benzoquinone ring system bridged at nonadjacent positions by an aliphatic chain. Alternative Names: PDM3. CAS No. 72902-38-6. Molecular formula: C31H41ClN2O9. Mole weight: 621.1. | |
| Ansamitocin P-3 | It is produced by the strain of Nocardia sp. C-15003(N-1). It has the function of anti-tumor, anti-plant pathogenic fungi, skin fungi and protozoa, and has no antibacterial activity. Uses: Inhibitor of tublin spiralization,maytansine analog. Alternative Names: 3-O-De[2-(acetylmethylamino)-1-oxopropyl]-3-O-(1-oxobutyl)-maytansine; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane; maytansine deriv.; Ansamitocin P 3; Antibiotic C 15003P3; Maytansinol Butyrate. Grades: ≥90% by HPLC. CAS No. 66584-72-3. Molecular formula: C32H43N2O9Cl. Mole weight: 635.14. | |
| Anserine | Anserine (β-alanyl-3-methylhistidine) is a dipeptide found in the skeletal muscle and brain of mammals and birds. It is a derivative of carnosine and can be used as an antioxidant in cosmetics and body care products. Alternative Names: L-Anserine; N-beta-Alanyl-3-methyl-L-histidine. CAS No. 584-85-0. Molecular formula: C10H16N4O3. Mole weight: 240.24. | |
| Antennapedia Peptide | Antennapedia Peptide, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptides. Alternative Names: L-Arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; N5-(diaminomethylidene)-L-ornithyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-N5-(diaminomethylidene)-L-ornithyl-N5-(diaminomethylidene)-L-ornithyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; Penetratin; Penetratin-1; Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys. Grades: ≥98%. CAS No. 188842-14-0. Molecular formula: C104H168N34O20S. Mole weight: 2246.73. | |
| Anthopleurin-A | Anthopleurin-A is isolated from the sea anemone, Anthopleura xanthogrammica, and has inotropic effects but no chronotropic effects on mammalian heart preparation. Alternative Names: H-Gly-Val-Ser-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Thr-Leu-Trp-Leu-Tyr-Pro-Ser-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Ala-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln-OH (Disulfide bridge: Cys4-Cys46, Cys6-Cys36, Cys29-Cys47); Neurotoxin AX1; AP-A; L-Glutamic acid, glycyl-L-valyl-L-seryl-L-cysteinyl-L-leucyl-L-cysteinyl-L-α-aspartyl-L-seryl-L-α-aspartylglycyl-L-prolyl-L-seryl-L-valyl-L-arginylglycyl-L-asparaginyl-L-threonyl-L-leucyl-L-serylglycyl-L-threonyl-L-leucyl-L-tryptophyl-L-leucyl-L-tyrosyl-L-prolyl-L-serylglycyl-L-cysteinyl-L-prolyl-L-serylglycyl-L-tryptophyl-L-histidyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-alanyl-L-histidylglycyl-L-prolyl-L-threonyl-L-isoleucylglycyl-L-tryptophyl-L-cysteinyl-L-cysteinyl-L-lysyl-, cyclic tris(disulfide); Neurotoxin AX-I; Anthopleurin A (Anthopleura xanthogrammica). Grades: 95%. CAS No. 60880-63-9. Molecular formula: C220H326N64O67S6. Mole weight: 5131.72. | |
| Anthranilamide | It is produced by the strain of Streptomyces sp. B7747. Antichlorella activity. MIC is 20-107μg/mL. Alternative Names: 2-AMINOBENZAMIDE; Benzamide, 2-amino-; o-Aminobenzamide; 2-Carbamoylaniline; Aminobenzamide; Anthranilimidic acid. Grades: 95 %. CAS No. 88-68-6. Molecular formula: C7H8N2O. Mole weight: 136.15. | |
| Anthranilic acid-[13C6] | Anthranilic acid-[13C6]. Alternative Names: 2-AA-13C6; 2-Aminobenzoic acid-13C6; Anthranilic acid-(phenyl-13C6). Grades: 98% (CP); 99% atom 13C. CAS No. 335081-06-6. Molecular formula: C[13C]6H7NO2. Mole weight: 143.09. | |
| Anthraquinone | Anthraquinone is used in dye manufacturing, the textile and pulp industries, and as a bird repellant. Alternative Names: 9,10-Anthraquinone; 9,10-Anthracenedione; 1,4,11,12-Tetrahydro-9,10-anthraquinone; Anthracene-9,10-quinone; Anthradione; Avipel; DAQ-N; Flight Control; Hoelite; Kawasaki SAQ; Morkit; NSC 7957; SAQ; Corbit. Grades: ≥98%. CAS No. 84-65-1. Molecular formula: C14H8O2. Mole weight: 208.21. | |
| Anthraquinone-1,5-disulfonic acid disodium salt | Anthraquinone-1,5-disulfonic acid disodium salt. Alternative Names: 5-anthracenedisulfonicacid,9,10-dihydro-9,10-dioxo-disodiumsalt; anthrachinon-1,5-disulfonandisodny; anthrachinon-1,5-disulfonansodny; disodiumanthraquinone-1,5-disulfonate; sodiumanthraquinone-1,5-disulfonate; ANTHRAQUINONE-1,5-DISULFONIC ACID DISODIUM SALT. Grades: >98.0%(T). CAS No. 853-35-0. Molecular formula: C14H6Na2O8S2. Mole weight: 412.3. | |
| Antibacterial peptide / melittin homolog | Antibacterial peptide / melittin homolog is an antimicrobial peptide and a synthetic analog of Melittin (H-4310). It has antibacterial activity against gram-negative bacteria. Alternative Names: Hecate / Antibacterial peptide / melittin homolog; H-Phe-Ala-Leu-Ala-Leu-Lys-Ala-Leu-Lys-Lys-Ala-Leu-Lys-Lys-Leu-Lys-Lys-Ala-Leu-Lys-Lys-Ala-Leu-OH. Grades: >97%. Molecular formula: C123H226N32O24. Mole weight: 2537.35. | |
| Antibiotic PF 1052 | Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma sp. It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively). Antibiotic PF 1052 inhibits neutrophil migration in a wound assay and reduces pseudopodia formation. Alternative Names: (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methylene)-1-methylpyrrolidine-2,4-dione; PF 1052; 3-[[2-(2,3-Dimethyl-2-oxiranyl)-1,2,4a,5,6,7,8,8a-octahydro-6,8-dimethyl-1-naphthalenyl]hydroxymethylene]-1-methyl-5-(1-methylpropyl)-2,4-pyrrolidinedione. Grades: ≥95%. CAS No. 147317-15-5. Molecular formula: C26H39NO4. Mole weight: 429.59. | |
| Anticapsin | Anticapsin is an antibiotic produced by Streptomyces griseoplanus. It can also be produced by acid hydrolysis of Bacilysin. 3 μg/mL Anticapsin can inhibit the formation of hyaluronic acid capsule by Streptococcus pyogenes. Except for Salmonella gallisepticum (MIC 6.25 μg/mL), low concentration has no obvious antibacterial activity against other microorganisms. Alternative Names: 7-Oxabicyclo[4.1.0]heptane-2-propanoic acid, (1R-(1.alpha.,2.alpha.(S*),6.alpha.))-. CAS No. 28978-07-6. Molecular formula: C9H13NO4. Mole weight: 199.20. | |
| Antimycin A1 | Antimycin A is a macrolide antibiotic produced by Streptomyces kitasawaensis, Str. griseus and Str. antibioticus. Antimycin A1 can inhibit atp-citrate lyase activity. Alternative Names: dihydrosamidin. Grades: >98% by HPLC. CAS No. 642-15-9. Molecular formula: C28H40N2O9. Mole weight: 548.62. | |
| Antipyrine | Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. It can also be used for animals. Alternative Names: Propyphenazone EP impurity A; Phenazone; Azophen; NSC 7945; NSC 7945; NSC 7945; Auralgan. Grades: >98%. CAS No. 60-80-0. Molecular formula: C11H12N2O. Mole weight: 188.23. | |
| Anwuligan | Macelignan is a natural compound isolated from Myristica fragrans Houtt. It possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation. Alternative Names: Anwuligan. Grades: >98%. CAS No. 107534-93-0. Molecular formula: C20H24O4. Mole weight: 328.4. | |
| Apalutamide-[d3] | Apalutamide-[d3] is an isotope analogue of Apalutamide which is a potent and competitive androgen receptor (AR) antagonist with potential antineoplastic activity. It binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. Alternative Names: 4-[7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-(methyl-d3)-benzamide. Grades: > 98%. CAS No. 1638885-61-6. Molecular formula: C21H12D3F4N5O2S. Mole weight: 480.45. | |
| Apelin-13 | Apelin-13, an endogenous neuropeptide, is the ligand for the G-protein-coupled receptor APJ, an alternative coreceptor with CD4 for HIV-1 infection. Apelin-13 is generated from apelin-36, which is a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with EC50 value of 0.37 nM. Apelin-13 is a 13 amino acid polypeptide encoded by the apelin gene which yields a pre-proprotein that is processed to generate bioactive peptides. Apelin-13 is also involved in the learning and memory process. Alternative Names: Apelin-13 (human, bovine, mouse, rat); H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH; L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysyl-glycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine. Grades: ≥95%. CAS No. 217082-58-1. Molecular formula: C69H111N23O16S. Mole weight: 1550.85. | |
| Aphidicolin | Aphidicolin is an antibiotic produced by Cephalosporium aphidicola and Nigrospora sphaerica, which has the effect of inhibiting mitosis and anti-DNA virus. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line. Uses: A reversible inhibitor of eukaryotic nuclear dna replication. Alternative Names: (+)-Aphidicolin; (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol. Grades: >98%. CAS No. 38966-21-1. Molecular formula: C20H34O4. Mole weight: 338.48. | |
| Apigenin | Apigenin is the main active ingredient of Chamomil Extract. Chamomile is rich in flavonoid active ingredients and has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. The active ingredients of chamomile can be applied to high-end anti-sensitive skin care products through issofree technology. It has a good soothing effect on itchy skin, it gently replenishes water and soothes the skin. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM. Apigenin is a good functional cosmetics material. Alternative Names: 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Flavone, 4',5,7-trihydroxy-; 4',5,7-Trihydroxyflavone; 5,7,4'-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 5,7-Dihydroxy-2-p-hydroxyphenyl-4-chromenone; Apegenin; Apigenine; Apigenol; C.I. Natural Yellow 1; Chamomile; LY 080400; NSC 83244; Pelargidenon 1449; ST 056301; UCCF 031; Versulin. Grades: >95%. CAS No. 520-36-5. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Apigenin 6,8-di-C-glucoside | Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Alternative Names: Vicenin II; Vicenin 2; Violantin. Grades: >98%. CAS No. 23666-13-9. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Apigenin-[d5] | Apigenin-[d5] is the labelled analogue of Apigenin, which is the main active ingredient of Chamomil extract. Chamomile is rich in flavonoid active ingredients, which has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. Alternative Names: Apigenin D5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5; 4',5,7-Trihydroxyflavone-d5; Pelargidenon 1449-d5; [3,6,8,3',5'-d5]-Apigenin. Grades: ≥96%. CAS No. 263711-74-6. Molecular formula: C15H5D5O5. Mole weight: 275.27. | |
| AP-III-a4 | AP-III-a4 is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 μM); inhibit cancer cell metastasis in vivo. Alternative Names: ENOblock. Grades: >98%. CAS No. 1177827-73-4. Molecular formula: C31H43FN8O3. Mole weight: 594.72. | |
| Apocynoside I | Apocynoside I is a natural product found in Apocynum cannabinum and Apocynum venetum. Alternative Names: Apocynoside I; AKOS040762622; 358721-31-0; (4R)-4-[(E,3R)-3-hydroxybut-1-enyl]-5,5-dimethyl-3-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]cyclohex-2-en-1-one. Grades: 96%. CAS No. 358721-31-0. Molecular formula: C19H30O8. Mole weight: 386.44. | |
| Apraglutide | Apraglutide is a synthetic long-acting GLP-2 analogue containing 33 amino acids that enhances the adaptation and linear intestinal growth of neonatal piglets in a model of short bowel syndrome with total ileal resection. Alternative Names: FE 203799; His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Nle-D-Phe-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2. Grades: ≥95%. CAS No. 1295353-98-8. Molecular formula: C172H263N43O52. Mole weight: 3765.25. | |
| Apramycin | Apramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Apramycin has a broad antibacterial spectrum and has a strong effect on both Gram-positive and negative bacteria. Uses: Anti-bacterial agents. Alternative Names: Nebramycin II; Nebramycin factor 2; Apramycinum; Apramicina; O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine; Ambylan; Apralan; Apralan 200 Injection; Apralin; EL 857; EL 857/820. Grades: >98%. CAS No. 37321-09-8. Molecular formula: C21H41N5O11. Mole weight: 539.58. | |
| Apramycin Sulfate | Apramycin is an aminoglycoside antibiotic produced by Streptomyces. It has activity against Gram-negative bacteria. It acts by blocking translocation and binding to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. Uses: Anti-bacterial agents. Alternative Names: FEMA 2131; FEMA2131; FEMA-2131; D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (1:x); D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (salt); O-4-Amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-D-streptamine sulfate; Nebramycin factor 2 sulfate. Grades: >98%. CAS No. 65710-07-8. Molecular formula: C21H41N5O11.xH2O4S. Mole weight: 539.58 (free base). | |
| Aprepitant-[d4] | Aprepitant-[d4] is the labelled analogue of Aprepitant. Aprepitant is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic agent. Alternative Names: Aprepitant D4; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend-d4; MK 0869-d4; MK 869-d4. Grades: ≥97%; ≥98% atom D. CAS No. 1133387-60-6. Molecular formula: C23H17D4F7N4O3. Mole weight: 538.46. | |
| Aprotinin | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue sample | |
| Arachidonic acid-[13C] | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Alternative Names: (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic-1-13C acid. CAS No. 488822-78-2. Molecular formula: C19[13C]H32O2. Mole weight: 305.47. | |
| Arachidonic acid-[13C20] | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Grades: > 98%. Molecular formula: [13C]20H32O2. Mole weight: 324.32. | |
| Arachidonic acid-[20-13C] | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. Grades: 98%; 99% atom 13C. Molecular formula: C19[13C]H32O2. Mole weight: 305.47. | |
| Arachidonic Acid-[d11] | Labelled Arachidonic acid. Arachidonic acid is an essential fatty acid and a precursor in the biosynthesis of thromboxanes, prostaglandins and leukotrienes. It is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. It is an important cellular signaling mediator in a variety of biological processes, including smooth chemotaxis, muscle contraction, apoptosis, cell proliferation and differentiation. It exits in liver, brain, glandular organs, and depot fats of animals and a constituent of animal phosphatides. It could bind to the subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). It stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules. Alternative Names: (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid-d11; (all-Z)-5,8,11,14-Eicosatetraenoic Acid-d11; 5,8,11,14-all-cis-Eicosatetraenoicmmunocytophyte-d11; Immunocytophyte-d11; all-cis-5,8,11,14-Eicosatetraenoic Acid-d11; cis-5,8,11,14-Eicosatetraenoic Acid-d11. Grades: 98% by CP; 98% atom D. CAS No. 1287387-84-1. Molecular formula: C20H21D11O2. Mole weight: 315.53. | |
| Arachidonic acid-[d8] | Arachidonic acid-[d8]. Alternative Names: cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic acid-5,6,8,9,11,12,14,15-d8; Arachidonic-5,6,8,9,11,12,14,15-d8 acid; Arachidonic acid-5,6,8,9,11,12,14,15-d8. Grades: 98% by CP; 98% atom D. CAS No. 69254-37-1. Molecular formula: C20H24D8O2. Mole weight: 312.52. | |
| Arbekacin sulfate | Arbekacin is a semi-synthetic aminoglycoside antibiotic used to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Alternative Names: Habekacin. CAS No. 104931-87-5. Molecular formula: C22H46N6O14S. Mole weight: 650.70. | |
| Arborine | Arborine is a natural compound isolated from the leaves of Glycosmis pentaphylla. Alternative Names: Glycosine. Grades: 98.5%. CAS No. 6873-15-0. Molecular formula: C16H14N2O. Mole weight: 250.301. | |
| Arbutin | Arbutin is a glycosylated hydroquinone extracted from bearberry plant. Arbutin acts as an inhibitor of tyrosinase, and is used as a skin-lightening agent for the prevention of melanin formation in skin conditions. It is a good functional cosmetics material. Uses: Skin-lightening agent. Alternative Names: 4-Hydroxyphenyl β-D-glucopyranoside; Hydroquinone-b-D-glucoside; Glucopyranoside, p-hydroxyphenyl, β-D-; Arbutine; Arbutoside; Arbutyne; Hydroquinone glucose; Hydroquinone β-D-glucopyranoside; NSC 4036; p-Arbutin; p-Hydroxyphenyl β-D-glucopyranoside; p-Hydroxyphenyl β-D-glucoside; Ursin; Uvasol; β-Arbutin. Grades: ≥98%. CAS No. 497-76-7. Molecular formula: C12H16O7. Mole weight: 272.25. | |
| Arctiin | Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir. Uses: Anticancer / anti-inflammatory. Alternative Names: 4-[(3,4-Dimethoxyphenyl)methyl]-3-[[4-(b-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-(3R,4R)-2(3H)-furanone. Grades: >98%. CAS No. 20362-31-6. Molecular formula: C27H34O11. Mole weight: 534.55. | |
| ar-Curcumene | ar-Curcumene is a component of essential oil of Hedychium larsenii with anti-inflammatory activity. Alternative Names: α-Curcumene; 1-methyl-4-[(2S)-6-methylhept-5-en-2-yl]benzene. Grades: 98.0%. CAS No. 4176-6-1. Molecular formula: C15H22. Mole weight: 202.341. | |
| [Arg8]-Vasotocin | [Arg8]-Angiotensin (AVT) is a neuropeptide peptide of the vasopressin / oxytocin hormone family, which has the function of regulating adrenal cortex hormones. Alternative Names: H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 8-L-arginine-; 1-9-Hydrin 2 (peptide), 9-glycinamide-; 8-L-Arginineoxytocin; 3-Isoleucine-8-arginine vasopressin; 8-L-Arginine-vasotocin; 8-Arginine oxytocin; 8-Arginine vasotocin; [Arg8]oxytocin; Arginine vasotocin; Arginine-vasotocin; Argiprestocin; Natriuretic hormone (ox pineal); Vasotocin (Neoceratodus forsteri); Vasotocin, 8-L-arginine-; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Grades: 95%. CAS No. 113-80-4. Molecular formula: C43H67N15O12S2. Mole weight: 1050.22. | |
| (Arg)9, FAM-labeled | It is a fluorescent (FAM)-labeled cell permeable peptide, Abs/Em=494/521 nm. Alternative Names: FAM-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH. Grades: ≥95%. Molecular formula: C75H120N36O16. Mole weight: 1781.99. | |
| Arg-Gly-Asp | RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Alternative Names: Arginyl-Glycyl-Aspartic acid; RGD peptide. Grades: Min 98%. CAS No. 99896-85-2. Molecular formula: C12H22N6O6. Mole weight: 346.34. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Alternative Names: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
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