BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Arginyl-glycine | Arginyl-glycine. Alternative Names: Arg-Gly; L-Arginyl glycine. CAS No. 2418-67-9. Molecular formula: C8H17N5O3. Mole weight: 231.25. |  |
| Arginyl-Methionine | Arginyl-Methionine. Alternative Names: Arg-Met; L-arginyl-L-methionine; RM dipeptide; N-L-Arginyl-L-methionine; Arginine Methionine dipeptide. Grades: ≥98%. CAS No. 45243-23-0. Molecular formula: C11H23N5O3S. Mole weight: 305.40. | |
| Argipressin | This molecular is a polypeptide which is a Antidiuretic hormone that has been found in most mammalian species and it acts as a neurotransmitter at synapses in the brain to increases[Ca2+]i in cultured rat hippocampal neurons. In the Past, Arg-vasopressin was applicated to treat diabetes insipidus or to improve vasomotor tone and blood pressure. In 2008, preclinical trials in Heart was failed in USA (Intranasal). Uses: Treat diabetes insipidus or to improve vasomotor tone and blood pressure. Alternative Names: Vasopressin; Arg8-vasopressin; AVP; H-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2. Grades: 95%. CAS No. 113-79-1. Molecular formula: C46H65N15O12S2. Mole weight: 1084.23. | |
| Arglabin | Arglabin is a sesquiterpene gamma-lactone and is isolated from Artemisia glabella. It is anticancer natural compound. Alternative Names: (+)-Arglabin. Grades: >98%. CAS No. 84692-91-1. Molecular formula: C15H18O3. Mole weight: 246.3. | |
| Aripiprazole | Aripiprazole binds with high affinity to both the G protein-coupled and uncoupled states of receptors. Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation. Alternative Names: OPC-14597; OPC 14597; OPC14597; Abilify; Abilitat; Abilify Discmelt. Grades: >98%. CAS No. 129722-12-9. Molecular formula: C23H27Cl2N3O2. Mole weight: 448.39. | |
| ARISTOLACTAM-AII | Aristolactam AII is an alkaloid compound found in the herbs of Aristolochia debilis Sieb. et Zucc. Aristolactam AII exhibits the activities of antiinflammatory and antimicrobial. Aristolactam AII also has platelet aggregation inhibitory activity. Uses: Antiinflammatory, antimicrobial. Alternative Names: 2-Hydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-one; 3-Hydroxy-4-methoxy-10-aminophenanthrene-1-carboxylic acid 1,10-lactam. Grades: >98%. CAS No. 53948-07-5. Molecular formula: C16H11NO3. Mole weight: 265.3. | |
| Aristolactam FI | Aristolactam FI is a natural alkaloid found in the roots of Piper longum, it shows platelet aggregation inhibitory activity and may be potential cancer chemotherapeutic and chemopreventive agents. Uses: Anti-cancer. Alternative Names: 1-Hydroxy-2-methoxydibenz[cd,f]indol-4(5H)-one; Piperolactam A. Grades: >95%. CAS No. 112501-42-5. Molecular formula: C16H11NO3. Mole weight: 265.3. | |
| Aristololactam BII | Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells. Uses: Anti-syncytium. Alternative Names: Cepharanone B. Grades: >97%. CAS No. 53948-09-7. Molecular formula: C17H13NO3. Mole weight: 279.3. | |
| Aristolone | Aristolone is isolated from the herbs of Aristolochia debilis Sieb. et Zucc. Alternative Names: 2H-Cyclopropa[a]naphthalen-2-one,1,1a,4,5,6,7,7a,7b-octahydro-1,1,7,7a-tetramethyl-, (1aR,7R,7aR,7bS)-rel-; Aristol-9-en-8-one. CAS No. 6831-17-0. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Aromadendrin | Aromadendrin, which usually comes from the bark of Eucalyptus calophylla, exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells. Aromadendrin may represent a potential therapeutic candidate for the management of type 2 DM. Uses: Anti-inflammatory / antioxidant / anti-diabetic. Alternative Names: 3,5,7,4'-Tetrahydroxyflavanone; Dihydrokaempferol; aromadedrin; (2R)-2,3-Dihydro-3β,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2R,3R)-2,3-Dihydro-2-(4-hydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Katuranin. Grades: >98%. CAS No. 480-20-6. Molecular formula: C15H12O6. Mole weight: 288.3. | |
| Artemether | Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria. Alternative Names: Dihydroartemisinin Methyl Ether; Falcidol; Gvither; Larither; Malartem; SM 224; β-Artemether; β-Dihydroartemisinin Methyl Ether; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin. Grades: >99%. CAS No. 71963-77-4. Molecular formula: C16H26O5. Mole weight: 298.37. | |
| Artemisinic acid | Artemisinic acid, a sesquiterpene isolated from Artemisia annua L, has a variety of pharmacological activities, such as antimalarial, antitumor, antipyretic, antibacterial, allelopathy, and anti-lipogenesis. Uses: Antibacterial. Alternative Names: 2-((1R,4R,4aS,8aS)-4,7-Dimethyldecahydronaphthalen-1-yl)acrylic Acid; [1R-(1α,4β,4aβ,8aβ)]-1,2,3,4,4a,5,6,8a-Octahydro-4,7-dimethyl-α-methylene-1-naphthaleneacetic Acid; (1R,4R,4aS,8aR)-1,2,3,4,4a,5,6,8a-Octahydro-4,7-dimethyl-α-methylene-1-naphthaleneacetic Acid; Arteannuic Acid; Arteannuinic Acid; Artemisic Acid; Artemisininic Acid; Qing Hao Acid; Qing Hau Acid. Grades: >98%. CAS No. 80286-58-4. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Artemisinin | Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is usually used in combination therapy for the treatment of malaria. Artemisinin is also used against a wide range of trematodes, including Schistosoma. Artemisinin is an inhibitor of human NOS2 (iNOS) with anticancer activity. Alternative Names: (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epox12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Artemisine; Arteannuin; Huanghuahaosu; QHS; Qinghaosu; (+)-Artemisinin. Grades: 98% by HPLC. CAS No. 63968-64-9. Molecular formula: C15H22O5. Mole weight: 282.33. | |
| Artesunate | Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis. Alternative Names: Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458. Grades: >99%. CAS No. 88495-63-0. Molecular formula: C19H28O8. Mole weight: 384.42. | |
| ar-turmerone | (+)-ar-Turmerone, a kind of aromatic compound, is a natural antibiotic used as an anti-tumor and immune-activating agent. It is known as a potent anti-venom against snake bites. It has been reported to promote stem cell proliferation, is a factor in nerve cell regeneration and brain injury, and has anti-inflammatory properties. It is widely used in anti-aging, removing wrinkles, whitening and lightening spots, antibacterial and anti-inflammatory, and anti-sensitivity repair products, and is compatible with lotion cream formulas, gel formulas and water formulas. Alternative Names: (S)-ar-Turmerone; (6S)-2-Methyl-6-(4-methylphenyl)-2-hepten-4-one; Turmerone, (S)-ar-; ar-(+)-Turmerone; ar-Tumerone; (S)-2-Methyl-6-(4-methylphenyl)-2-hepten-4-one; (+)-(S)-ar-Turmerone. Grades: ≥97%. CAS No. 532-65-0. Molecular formula: C15H20O. Mole weight: 216.32. | |
| Ascamycin | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. The MIC values of Ascamycin against Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei are 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL, respectively. Alternative Names: (+)-5'-O-[[(S)-2-Amino-1-oxopropyl]aminosulfonyl]-2-chloroadenosine; 2-Chloro-5'-O-[(L-alanylamino)sulfonyl]adenosine; 2-Chloro-5'-O-[[(S)-2-amino-1-oxopropyl]sulfamoyl]adenosine; 5'-O-{[(2S)-2-Amino-1-hydroxypropylidene]sulfamoyl}-2-chloroadenosine. Grades: ≥95%. CAS No. 91432-48-3. Molecular formula: C13H18ClN7O7S. Mole weight: 451.84. | |
| Ascorbic Acid-[d4] | Ascorbic Acid-[d4] is a labelled Ascorbic Acid. Ascorbic Acid, also known as Vitamin C, is a naturally occurring organic compound with antioxidant properties. It is used to prevent and treat scurvy. Vitamin C is an essential nutrient involved in the repair of tissue and the enzymatic production of certain neurotransmitters. Alternative Names: (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one. Molecular formula: C6H4O6D4. Mole weight: 180.15. | |
| Asebogenin | Asebogenin is extracted from the leaves of Pieris japonica. It can inhibit the proliferation of murine B cells. It displays antiplasmodial activities against both a resistant strain and a chloroquine-sensitive of Plasmodium falciparum. It also shows anti-bacterial activity. It inhibits methicillin-resistant S. aureus and S. aureus with IC50 values of 4.5 and 10 micrograms/ml respectively. It is a predicted metabolite generated by BioTransformer. It is generated through an o-dealkylation reaction, which occurs in humans and is generated by cyp1a2, cyp2c9 and cyp2c19 enzymes. Alternative Names: 4'-O-Methylphloretin; 1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone. Grades: 98%. CAS No. 520-42-3. Molecular formula: C16H16O5. Mole weight: 288.29. | |
| Asiatic acid | Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing. Asiatic acid has the potential for skin cancer treatment. Asiatic acid also has anti-inflammatory activities. Uses: Antihyperlipidemic. Alternative Names: Dammarolic acid; Asiantic acid; NSC 166063; 2,3,23-trihydroxyurs-12-en-28-oic acid. Grades: > 98 %. CAS No. 464-92-6. Molecular formula: C30H48O5. Mole weight: 488.70. | |
| Asiaticoside | Asiaticoside is a natural triterpenoid found in the herbs of Centella asiatica (L.) Urban. Asiaticoside shows anxiolytic-like and antidepressant-like effects. Asiaticoside may be useful for the anti-gastric ulcers and also can be used in cosmetic material. Uses: Anti-infective agents. Alternative Names: Madecassol. Grades: >95%. CAS No. 16830-15-2. Molecular formula: C48H78O19. Mole weight: 959.13. | |
| Asimilobine | Asimilobine is a natural alkaloid compound found in several plants. Alternative Names: (R)-5,6,6a,7-Tetrahydro-1-methoxy-4H-dibenzo[de,g]quinolin-2-ol;1-Methoxy-6abeta-noraporphin-2-ol. Grades: >98%. CAS No. 6871-21-2. Molecular formula: C17H17NO2. Mole weight: 267.322. | |
| Asparaginyl-glutamine | Asparaginyl-glutamine is a dipeptide composed of asparagine and glutamine. CAS No. 14608-83-4. Molecular formula: C9H16N4O5. Mole weight: 260.25. | |
| Asparaginyl-glycine | Asparaginyl-glycine is a dipeptide composed of asparagine and glycine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Glycine, N-L-asparaginyl-; H-NG-OH; L-asparagyl-glycine; L-asparaginylglycine; Asn-Gly; L-Asn-Gly; (S)-2-(2,4-Diamino-4-oxobutanamido)acetic acid. Grades: ≥95%. CAS No. 67576-72-1. Molecular formula: C6H11N3O4. Mole weight: 189.17. | |
| Asparaginyl-histidine | Asparaginyl-histidine is a dipeptide composed of asparagine and histidine. Alternative Names: L-Asparaginyl-L-histidine. CAS No. 224638-52-2. Molecular formula: C10H15N5O4. Mole weight: 269.26. | |
| Asparaginyl-proline | Asparaginyl-proline is a dipeptide composed of asparagine and proline. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Proline, 1-L-asparaginyl-; H-NP-OH; L-asparagyl-L-proline; Asn-Pro; L-Asn-L-Pro. Grades: ≥95%. CAS No. 78346-95-9. Molecular formula: C9H15N3O4. Mole weight: 229.23. | |
| Aspartame | Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages. Uses: aspartame is a dipeptide compound composed of two amino acids (aspartic acid and phenylalanine) and a methyl ester bond. it was discovered in 1965 and approved for use by the u.s. food and drug administration (fda) in 1981. aspartame is extremely sweet, about 200 times sweeter than sucrose (table sugar), so only a very small amount is needed to achieve the desired sweetness. aspartame is often. Alternative Names: L-α-Aspartyl-L-phenylalanine 2-Methyl Ester; Canderel; Dipeptide Sweetener; E 951; Equal; Finn; L-Aspartame; NutraSweet; Pal Sweet; Palsweet Diet; Sweet Dipeptide; Zero-Cal; α-Aspartame; α-L-Aspartyl-L-phenylalanine Methyl Ester; α-Sweet. Grades: >98%. CAS No. 22839-47-0. Molecular formula: C14H18N2O5. Mole weight: 294.31. | |
| Aspartame Impurity C | A metabolite of Aspartame. Alternative Names: 2-Amino-3-Phenylpropanoic Acid; H-DL-Phe-OH; DL-3-Phenylalanine; DLPA. Grades: 98.5-101.5% (Assay by titration). CAS No. 150-30-1. Molecular formula: C9H11NO2. Mole weight: 165.19. | |
| Asperuloside | Asperuloside is an iridoid monoterpenoid glycoside with anti-angiogenic, anti-inflammatory, and anti-obesity properties. Uses: Anti-inflammatory. Alternative Names: [2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate. Grades: 98%. CAS No. 14259-45-1. Molecular formula: C18H22O11. Mole weight: 414.36. | |
| Aspirin | Aspirin is a salicylate and irreversible COX1 and COX2 inhibitor. It can be used for the treatment of fever, rheumatism, nerve, muscle, joint pain, soft tissue inflammation and gout in animals. Alternative Names: Acetylsalicylic acid. Grades: 99.5%. CAS No. 50-78-2. Molecular formula: C9H8O4. Mole weight: 180.16. | |
| Aspirin Impurity | A metabolite of Acetylsalicylic Acid. Alternative Names: 2-(2,4-Dihydroxybenzoyl)benzoic Acid. Grades: > 95%. CAS No. 2513-33-9. Molecular formula: C14H10O5. Mole weight: 258.23. | |
| Astaxanthin | Astaxanthin is a carotenoid pigment found mostly in animal organisms, but also occurring in plants. It is thought to be the precursor of astacin. It is a potent lipid-soluble antioxidant. It has broad application prospects in health products, medicine, cosmetics, food additives and aquaculture. Astaxanthin is a natural antioxidant with the strongest antioxidant and anti-aging ability in nature, and its antioxidant capacity is much higher than VE and β-carotene. It significantly enhances mitochondrial activity required for cell recombination and effectively protects the skin from UVA, UVB and blue light damage. Uses: Ingredient of health care products. Alternative Names: Ovoester; Astaxanthine; (3S,3'S)-Astaxanthin; All-trans-Astaxanthin; 3,3'-Dihydroxy-β,β-carotene-4,4'-dione; 3,3'-Dhydroxy-4,4'-diketo-β-carotene; trans-Astaxanthin; (3S,3'S)-all-trans-Astaxanthin; (6S,6'S)-3,3'-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone). Grades: 95% by HPLC. CAS No. 472-61-7. Molecular formula: C40H52O4. Mole weight: 596.84. | |
| Asterric acid | Asterric acid is an Endothelin (ET) binding inhibitor produced by Aspergillus sp. Alternative Names: Dimethylosoic acid,TAN 1415A, WF 12880A. Grades: >98%. CAS No. 577-64-0. Molecular formula: C17H16O8. Mole weight: 348.30. | |
| Astragalin | Astragalin is a flavonoid with anti-inflammatory activity and newly found in persimmon leaves and green tea seeds. Uses: Anti-inflammatory. Alternative Names: Astragaline; 3,4,5,7-Tetrahydroxyflavone-3-glucoside. Grades: >98%. CAS No. 480-10-4. Molecular formula: C21H20O11. Mole weight: 448.38. | |
| Astragaloside IV | Astragaloside IV is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. It has anti-aging properties, antioxidant, anti-inflammatory and anti-fibrotic effects in systemic sclerosis. It inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-α-ERK1/2-NF-κB pathway. Astragaloside IV is a natural compound used in cosmetics material. Uses: Cardiovascular protection. Alternative Names: 9,19-Cyclolanostan-beta-D-glucopyranoside; 20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl. Grades: >98%. CAS No. 84687-43-4. Molecular formula: C41H68O14. Mole weight: 784.97. | |
| Astressin 2B | Astressin 2B is a selective and potent corticotropin-releasing factor receptor 2 (CRF2) antagonist with IC50 values of > 500 nM and 1.3 for CRF1 and CRF2 respectively. It antagonizes CRF2-mediated inhibition of gastric emptying. Alternative Names: Cyclo(31-34)[D-Phe11,His12,C(α)MeLeu13,39,Nle17,Glu31,Lys34]Ac-Svg(8-40). Grades: >98%. CAS No. 681260-70-8. Molecular formula: C183H307N49O53. Mole weight: 4041.69. | |
| AT-265 | AT-265 is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity. Alternative Names: 5'-Sulfamoyl-2-chloroadenosine; 2-chloro-5'-o-sulfamoyladenosine; Antibiotic AT 265. Grades: >98%. CAS No. 66522-52-9. Molecular formula: C10H13ClN6O6S. Mole weight: 380.77. | |
| ATI-2341 | A potent and functionally selective allosteric agonist of CXCR4. Alternative Names: ATI 2341; palmitoyl-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu-OH; N-palmitoyl-L-methionyl-glycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-L-leucine; ATI2341; 1-Oxohexadecyl-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu. Grades: ≥95%. CAS No. 1337878-62-2. Molecular formula: C104H178N26O25S2. Mole weight: 2256.82. | |
| Atorvastatin calcium | Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Grades: >98%. CAS No. 134523-03-8. Molecular formula: 2(C33H34FN2O5).Ca. Mole weight: 1155.34. | |
| Atovaquone | Atovaquone is a medication used to treat or prevent pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. Uses: Antipneumocystic. Alternative Names: Mepron; Wellvone; Acuvel; 566C80; 566C; BW 566C; 2-(trans-4-(p-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone. Grades: 98%. CAS No. 95233-18-4. Molecular formula: C22H19ClO3. Mole weight: 366.84. | |
| Atovaquone-[d4] | Atovaquone-[d4] is a labelled Atovaquone. Atovaquone is a chemical compound with therapeutic effect against pneumocystis pneumonia (PCP), malaria, babesia, etc. Alternative Names: 2-[trans-4-(4-Chlorophenyl-d4)cyclohexyl-]-3-hydroxy-1,4-naphthalenedione; 566C80-d4; BW-566C-d4; BW-566C-80-d4; Mepron-d4; Wellvone-d4. Grades: 98.5% HPLC; 98% atom D. CAS No. 2070015-14-2. Molecular formula: C22H15DClO3. Mole weight: 370.87. | |
| Atpenin A5 | Atpenin A5 is an inhibitor of SDHB, SDHC and SDHD. It is an antifungal antibiotic produced by Penicillium sp. and an ubiquinone-binding site inhibitor of succinate dehydrogenase with IC50s of 12 nM for nematode and IC50s of 3.7 nM for mammalian mitochondria. Atpenin A5 is the most effective inhibitor against complex II from all the atpenins and has been shown to protect against cardiac-reperfusion injury in rat studies through the stimulation of mitochondrial KATP channels. Alternative Names: Antibiotic FO-125A5. Grades: ≥95%. CAS No. 119509-24-9. Molecular formula: C15H21Cl2NO5. Mole weight: 366.2. | |
| Atractylodin | Atractylodin is an active component of the essential oil contained in the rhizomes of Atractylodes lancea and A. Uses: Anti-inflammatory. Alternative Names: Atractydin. Grades: >98%. CAS No. 55290-63-6. Molecular formula: C13H10O. Mole weight: 182.22. | |
| Atranorin | Atranorin, which can be found in the herbs of Parmelia tinctorum Despr, has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical. Also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2). It was found to be more efficient at equitoxic doses and correlated more strongly with an increased number of floating cells or a higher apoptotic index. It also exhibited significant anti-inflammatory activity in the acute model of inflammation (leukocyte migration to the peritoneal cavity), carrageenan- and arachidonic acid-induced hind paw edema in rats. Besides, Atranorin exhibited a dose-dependent antioxidant activity in vitro, as assessed by total radical-trapping antioxidant parameter and total antioxidant reactivity assays. Uses: Antinociceptive / antiinflammatory / antibacterial. Alternative Names: Atranoric acid; Atranorine; Parmelin; Usnarin; Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester. Grades: 98%. CAS No. 479-20-9. Molecular formula: C19H18O8. Mole weight: 374.34. | |
| Atraric acid | Atraric acid is a natural plant phenol found in the fruits of Vitis vinifera L, it inhibits the invasiveness of LNCaP cells through extracellular matrix. Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, which can be used for prophylaxis or treatment of prostatic diseases. Alternative Names: 2,4-dihydroxy-3,6-dimethyl-benzoicacimethylester. Grades: >98%. CAS No. 4707-47-5. Molecular formula: C10H12O4. Mole weight: 196.2. | |
| Atropine | Atropine is an alkaloid as an nerve agent that occurs naturally in plants of the nightshade family. Uses: Used as a pesticide poisoning and as a muscle relaxant when injected intravenously. Alternative Names: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate; L-Hyoscyamine; Hyoscyamine. Grades: ≥98%. CAS No. 51-55-8. Molecular formula: C17H23NO3. Mole weight: 289.37. | |
| Attacin-C | Attacin-C is an antimicrobial peptide produced by Drosophila melanogaster (Fruit fly). It has antibacterial and antifungal activity. Alternative Names: AttC; Gln-Arg-Pro-Tyr-Thr-Gln-Pro-Leu-Ile-Tyr-Tyr-Pro-Pro-Pro-Pro-Thr-Pro-Pro-Arg-Ile-Tyr-Arg-Ala. Grades: >98%. Molecular formula: C133H198N34O32. Mole weight: 2785.24. | |
| Aucubin | Aucubin is an iridoid glycoside with a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities. It may be a potential therapeutic choice in the treatment of OA due to its anti-inflammatory and chondroprotective features. Administration of Aucubin improved nerve regeneration in the rat model of sciatic nerve injury, suggesting that Aucubin may be a useful therapeutic compound for the human peripheral nervous system after various nerve injuries. Besides, Aucubin may improve obesity-induced atherosclerosis by attenuating TNF-α-induced inflammatory responses. Uses: Anti-inflammatory / chondroprotective. Alternative Names: (1S,4aR,5S,7aS)-1-4a,5,7a-Tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl b-D-glucopyranoside. Grades: >98%. CAS No. 479-98-1. Molecular formula: C15H22O9. Mole weight: 346.33. | |
| Aurachin C | Aurachin C is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-14-9. Molecular formula: C25H33NO2. Mole weight: 379.53. | |
| Aurachin D | Aurachin D is a quinoline compound produced by Stigmatella aurantiaca Sg al5. It has the activity of inhibiting gram-positive bacteria and a few yeasts and filamentous fungi, and can block the NADH oxidation of bovine heart microsomal particles. CAS No. 108354-13-8. Molecular formula: C25H33NO. Mole weight: 363.53. | |
| Auraptenol | Auraptenol is a natural coumarin found in the fruits of Citrus aurantium. It has antifibrotic activity and the anti-hyperalgesic action which may be as a novel analgesic for the management of neuropathic pain. Uses: Antifibrotic, anti-hyperalgesic. Alternative Names: (+)-8-(2-Hydroxy-3-methyl-3-butenyl)-7-methoxy-2H-1-benzopyran-2-one. Grades: >98%. CAS No. 1221-43-8. Molecular formula: C15H16O4. Mole weight: 260.3. | |
| Aureobasidin A | Aureobasidin A is a cyclic depsipeptide antibiotic isolated from the filamentous fungus Aureobasidium pullulans R106. It is an antifungal agent that inhibits phosphorylceramide synthase. Alternative Names: Basifungin. CAS No. 127785-64-2. Molecular formula: C60H92N8O11. Mole weight: 1101.42. | |
| Aureothin | Aureothin is produced by the strain of Streptomyces thioluteus 4-A-1 and Streptomyces sp. 58. An unusual pyranone metabolite; has broad biological actions including antitumour, antimicrobial and insecticidal activities; a potent inhibitor of helicobacter pylori. Alternative Names: Distacin; Mycolutein. Grades: >95% by HPLC. CAS No. 2825-00-5. Molecular formula: C29H26ClF3N2O6. Mole weight: 591. | |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| Aurodox | It is produced by the strain of Streptomyces goldiniensis var. goldiniensis. Aurodox is a polyketide antibiotic originally isolated from S. goldiniensis, which inhibits bacterial protein biosynthesis by interrupting the functional cycle of Elongation Factor-Tu (EF-Tu). Aurodox is a type 3 secretion system (T3SS) inhibitor and growth promotor in poultry. It is active against Gram-positive bacteria, including B. megaterium, B. anthracis, and M. hominis (MICs = 0.06, 0.6, and 3-10 μg/ml, respectively). Alternative Names: Antibiotic X 5108; Goldinodox; Goldinomycin; 1-methyl-Mocimycin; Benzamide; CYT11387. Grades: ≥95%. CAS No. 12704-90-4. Molecular formula: C44H62N2O12. Mole weight: 810.97. | |
| Avanafil | A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction. Alternative Names: TA-1790; TA 1790; TA1790; Avanafil; trade name: Stendra; Spedra. Grades: 99%. CAS No. 330784-47-9. Molecular formula: C23H26ClN7O3. Mole weight: 483.95064. | |
| Avermectin A1a | Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Alternative Names: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10. | |
| Avermectin B1a | It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Alternative Names: Ivermectin EP Impurity A; Abamectin B1a; Doramectin Impurity 3. Grades: ≥95%. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08. | |
| Avermectin B1b | Avermectin B1b is the minor component of the commercially available anthelmintic marketed as Abamectin. It is used broadly against nematodes, ticks, flies, and ants. Alternative Names: Ivermectin EP Impurity B; 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-avermectin A1a; Doramectin Impurity 2. Grades: ≥95%. CAS No. 65195-56-4. Molecular formula: C47H70O14. Mole weight: 859.05. | |
| Avermectin B2a | Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Alternative Names: Ivermectin EP Impurity C; (23S)-5-O-demethyl-23-hydroxy-22,23-dihydro-avermectin A1a. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09. | |
| Averufin | Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Alternative Names: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Avibactam-[13C5] sodium salt | Avibactam-[13C5] sodium salt is the labelled analogue of Avibactam sodium salt. Avibactam Sodium Salt, a novel β-lactamase inhibitor with a non-lactam structural. In combination with ceftazidime, Avibactam is a new drug to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Alternative Names: [13C5]-Avibactam sodium salt; Avibactam-13C5 Sodium Salt. Molecular formula: C2[13C]5H10N3NaO6S. Mole weight: 292.19. | |
| Avilamycin | Avilamycin is an antimicrobial agent that is active mainly against Gram-positive bacteria and is used against methicillin-resistant staphylococcus. Uses: Anti-bacterial agents. Alternative Names: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax; (2R,3S,4R,6S)-6-(((3a'R,4R,4'R,5S,6R,6'S,7a'R)-6'-(((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5S,6S)-6-(((2R,3aS,3a'R,6S,6'R,7R,7aR,7'S,7a'R)-7'-acetyl-7'-hydroxy-7-(isobutyryloxy)-6'-methyloctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl)oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-4',6,7a'-trimethyloctahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-5-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate. Grades: > 95%. CAS No. 11051-71-1. Molecular formula: C61H88Cl2O32. Mole weight: 1404.24. | |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Alternative Names: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. Grades: 98%. CAS No. 40077-57-4. Molecular formula: C147H238N44O42S. Mole weight: 3325.80. | |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Alternative Names: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. Grades: ≥98%. CAS No. 319460-85-0. Molecular formula: C22H18N4OS. Mole weight: 386.5. | |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb / IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Alternative Names: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grades: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79. | |
| Azacytidine-[13C5] | Labelled Azacytidine, produced by the strain of Streptoverticillium ladakanus var. ladakanus UC-2654. Azacitidine (Vidaza) is a chemotherapy drug used to treat conditions that affect the blood and the bone marrow, called myelodysplastic syndromes (MDS). It may also be used to treat other cancers, such as acute myeloid leukaemia (AML) or chronic myelomonocytic leukaemia (CMML). It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 μM for in vitro anti-myeloma activity) and cancer (IC50s ~ 0.4 μM for inhibiting proliferation of various cancer cell lines). It can also act as a demethylating agent by inhibiting DNA methyltransferase. Alternative Names: 4-Amino-1-[3,4-dihydroxy-5-(hydroxy(113C)methyl)(2,3,4,5-13C4)oxolan-2-yl]-1,3,5-triazin-2-one. Grades: 99%. Molecular formula: C3[13C]5H12N4O5. Mole weight: 249.17. | |
| Azetidine-[d6] | Azetidine-[d6] is a labelled form of Azetidine. Alternative Names: (2,2,3,3,4,4-D6)azetidine. CAS No. 1415638-24-2. Molecular formula: C3HD6N. Mole weight: 63.13. | |
| Azido-PEG2-amine | Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: Azide-PEG3-Amine;2-[2-(2-Azidoethoxy)ethoxy]ethanamine; Azido-PEG2-C2-amine; N3-PEG2-CH2CH2NH2. Grades: ≥95%. CAS No. 166388-57-4. Molecular formula: C6H14N4O2. Mole weight: 174.20. | |
| Azido-PEG3-FLAG | Azido-PEG3-FLAG is used for the attachment of the FLAG-tag by copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), a prototypical reaction of click chemistry. In addition, it contains a PEG linker. The resulting FLAG-tagged molecules can be detected or purified immunologically, using dye-labeled, enzyme coupled, or purification and immobilization of anti-Flag antibodies. Alternative Names: Azido-PEG3-propionyl-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH. Grades: ≥95%. CAS No. 2243206-95-1. Molecular formula: C50H75N13O24. Mole weight: 1242.22. | |
| Azido-PEG3-maleimide | Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG3-maleimide is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: Azido-PEG3-Maleimide Kit;N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide. Grades: >98.0%. CAS No. 1858264-36-4. Molecular formula: C15H23N5O6. Mole weight: 369.37. | |
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