BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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Boc-6-Aminohexanoic acid
Boc-6-aminohexanoic acid is a PROTAC linker, which is composed of alkyl chains. Boc-6-aminohexanoic acid can be used to synthesize a range of PROTACs. Alternative Names: Boc-ε-Acp-OH; Boc-ε-Ahx-OH; Boc ε Acp OH; Boc ε Ahx OH. Grades: ≥ 99% (HPLC). CAS No. 6404-29-1. Molecular formula: C11H21NO4. Mole weight: 231.29.
Boc-8-Amino-3,6-dioxaoctanoic acid DCHA
Boc-8-Amino-3,6-dioxaoctanoic acid is a PEG linker containing a protected amino group and a carboxylic acid. The carboxylic acid can be reacted with amino groups in the presence of activators. Alternative Names: Boc-AEEA-OH DCHA; Boc-8-Adox-OH DCHA; 8-(t-Butoxycarbonyl)amino-3,6-dioxaoctanoic acid dicyclohexylammonium salt; Dicyclohexylamine 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oate; N-cyclohexylcyclohexanamine,2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid; (2-[2-(Boc-amino)ethoxy]ethoxy)acetic acid dicyclohexylamine; 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid dicyclohexylamine. Grades: ≥ 99% (HPLC). CAS No. 560088-79-1. Molecular formula: C23H44N2O6. Mole weight: 444.61.
Boc-Ala-Ala-Pro-OH
Boc-Ala-Ala-Pro-OH is a building block for obtaining rhodamine-derived enzyme substrates. Alternative Names: Boc-L-alanyl-L-alanyl-L-proline; (S)-1-((S)-2-((S)-2-(tert-butoxycarbonylamino)propanamido)propanoyl)pyrrolidine-2-carboxylic acid. Grades: 95%. CAS No. 63769-98-2. Molecular formula: C16H27N3O6. Mole weight: 357.40.
Boc-Ala-Gly-Gly-OH
Boc-Ala-Gly-Gly-OH. Alternative Names: (Tert-butoxycarbonyl)-L-alanylglycylglycine; (S)-2,2,6-trimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oic acid. Grades: 95%. CAS No. 115035-47-7. Molecular formula: C12H21N3O6. Mole weight: 303.31.
Boc-Ala-OH-[3-13C]
Boc-Ala-OH-[3-13C]. Alternative Names: N-(tert-Butoxycarbonyl)-L-alanine-3-13C; L-Alanine-3-13C; Boc-Ala-OH-3-13C. Grades: 99% atom 13C. CAS No. 201740-79-6. Molecular formula: C7[13C]H15NO4. Mole weight: 190.20.
Boc-Ala-OH-[3,3,3-d3]
Boc-Ala-OH-[3,3,3-d3] is a labelled L-Alanine-N-t-BOC. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: BOC-L-Ala-OH-d3; L-Alanine-3,3,3-d3-N-t-BOC; N-(tert-Butoxycarbonyl)-L-alanine-3,3,3-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 161602-47-7. Molecular formula: C8H12D3NO4. Mole weight: 192.23.
Boc-Arg-OH
Boc-Arg-OH. Alternative Names: (S)-2-((tert-Butoxycarbonyl)amino)-5-guanidinopentanoic acid; Boc-L-Arg-OH. CAS No. 13726-76-6. Molecular formula: C11H22N4O4. Mole weight: 274.32.
Boc-Asp(OBzl)-OH-[13C4,15N]
Boc-Asp(OBzl)-OH-[13C4,15N] is a labelled Boc-Asp(OBzl)-OH, which is a protected L-Aspartic acid. Aspartic Acid is an α-amino acid used in the biosythesis of proteins. It is a non-essential amino acid for humans. Alternative Names: L-Aspartic acid-13C4,15N-N-T-BOC, B-BZ ester. Grades: 98% by HPLC; 98% atom 13C, 98% atom 15N. CAS No. 202326-58-7. Molecular formula: C12[13C]4H21[15N]O6. Mole weight: 328.31.
Boc-β-alanine Merrifield resin
Pre-loaded resins for solid phase peptide and organic synthesis. Alternative Names: Boc-β-Ala-Merrifield resin.
Boc-β-iodo-Ala-OtBu
Boc-β-iodo-Ala-OtBu. Alternative Names: (R)-2-tert-butoxycarbonylamino-3-iodopropionic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-3-iodo-L-alanine tert-butyl ester; Boc β iodo Ala OtBu. CAS No. 1057341-65-7. Molecular formula: C12H22INO4. Mole weight: 371.21.
Boc-Dap-OH
Boc-Dap-OH is a pivotal compound extensively utilized in the biomedical sector. It assumes a fundamental function in the amalgamation of diverse pharmaceutical remedies and peptides. This indispensable product profoundly contributes to the progression of therapeutics targeting ailments like cancer and viral infections. Alternative Names: N-Boc-dolaproine; BOC-DAP; (2R,3R)-BOC-dolaproine; (2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid. Grades: 95%. CAS No. 120205-50-7. Molecular formula: C14H25NO5. Mole weight: 287.35.
Boc-D-Asp(OMe)-OH. Alternative Names: (R)-2-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid; N-Boc-D-aspartic Acid 4-Methyl Ester. CAS No. 124184-67-4. Molecular formula: C10H17NO6. Mole weight: 247.3.
Boc-D-citrulline
Boc-D-citrulline. Alternative Names: Boc-D-Cit-OH; (R)-2-Boc-amino-5-ureidopentanoic acid; Boc-D-Orn(carbamoyl)-OH; Boc D Cit OH. Grades: ≥ 98% (NMR). CAS No. 121080-95-3. Molecular formula: C11H21N3O5. Mole weight: 275.30.
Boc-D-cysteine
Boc-D-cysteine is an N-Boc-protected form of D-Cysteine. D-Cysteine is a strong inhibitor of Escherichia coli growth and also functions to provide inorganic sulfates for the sulfation of xenobiotics. D-Cysteine is a non-physiological isomer of L-Cysteine, and is not involved in protein or glutathione synthesis. Alternative Names: Boc-D-Cys-OH; N-Boc-D-cysteine; Boc-D-cysteine; (S)-2-((tert-Butoxycarbonyl)amino)-3-mercaptopropanoic acid; D-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-; (tert-Butoxycarbonyl)-D-cysteine; Boc-D-Cys-OH; (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoic acid; AmbotzBAA1170; N-[(1,1-dimethylethoxy)carbonyl]-D-cysteine; Boc D Cys OH. Grades: ≥ 99% (Assay by titration). CAS No. 149270-12-2. Molecular formula: C8H15NO4S. Mole weight: 221.30.
tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy. Alternative Names: Boc-Gly-N(OMe)Me; tert-Butyl (2-[methoxy(methyl)amino]-2-oxoethyl)carbamate; N-Boc-glycine N'-methoxy-N'-methylamide; 2-(Boc-amino)-N-methoxy-N-methylacetamide. Grades: ≥ 99 % (HPLC). CAS No. 121505-93-9. Molecular formula: C9H18N2O4. Mole weight: 218.30.
Boc-Gly-Gly-Gly-Gly-OH
Boc-Gly-Gly-Gly-Gly-OH. Alternative Names: Boc-(Gly)4-OH; 2,2-Dimethyl-4,7,10,13-Tetraoxo-3-Oxa-5,8,11,14-Tetraazahexadecan-16-Oic Acid. Grades: 95%. CAS No. 174308-47-5. Molecular formula: C13H22N4O7. Mole weight: 346.34.
Boc-Gly-Gly-Phe-OH
Boc-Gly-Gly-Phe-OH is a biochemical compound widely used in the biomedical industry. It acts as a potent inhibitor, targeting specific enzymes involved in the growth and proliferation of cancer cells. This product demonstrates promising potential in the treatment of various types of cancers by hindering their progression and metastasis. Alternative Names: (tert-Butoxycarbonyl)glycylglycyl-L-phenylalanine; N-(tert-Butoxycarbonyl)glycylglycyl-L-phenylalanine; N-[N-[N-(tertbutoxycarbonyl)glycyl]glycyl]-L-phenylalanine. CAS No. 39621-73-3. Molecular formula: C18H25N3O6. Mole weight: 379.41.
Boc-Gly-OH-[13C2]
Boc-Gly-OH-[13C2]. Alternative Names: N-(tert-Butoxycarbonyl)glycine-13C2; Glycine-13C2, N-t-Boc derivative; Boc-Gly-OH-13C2. Grades: 99% atom 13C. CAS No. 145142-99-0. Molecular formula: C5[13C]2H13NO4. Mole weight: 177.17.
Boc-Gly-OH-[13C2,15N]
Boc-Gly-OH-[13C2,15N] is a labelled analogue of Boc-Gly-OH, which is for the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry. Alternative Names: N-(tert-Butoxycarbonyl)glycine-13C2,15N; Boc-glycine-13C2,15N. Grades: 98% by CP; 97% atom 13C; 97% atom 15N. CAS No. 145142-98-9. Molecular formula: C5[13C]2H13[15N]O4. Mole weight: 178.16.
Boc-Gly-Pro-OH
Boc-Gly-Pro-OH. Alternative Names: Boc-L-glycyl proline. Grades: ≥ 99% (HPLC). CAS No. 14296-92-5. Molecular formula: C12H20N2O5. Mole weight: 272.3.
Boc-His(Boc)-Aib-OH
Boc-His(Boc)-Aib-OH. CAS No. 1169630-98-1. Molecular formula: C20H32N4O7. Mole weight: 440.50.
Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH
It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Alternative Names: N2-(2-((S)-2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoyl)-N5-trityl-L-glutaminylglycine. Grades: 95%. CAS No. 3034670-38-4. Molecular formula: C60H63N7O8. Mole weight: 1010.19.
Boc-His(Trt)-Aib-OH
Boc-His(Trt)-Aib-OH, a highly specialized peptide synthesis reagent employed within the biomedical industry, presents a powerful capability for the creation of peptide sequences inclusive of unconventional amino acids. Its steadfast utilization helps to promote the generation of distinct and optimal peptide architectures, critical for the progression of targeted drug development, including the likes of Alzheimer's disease, cancer and many other diseases. Alternative Names: (S)-2-(2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid. CAS No. 2061897-68-3. Molecular formula: C34H38N4O5. Mole weight: 582.7.
Boc-HoTyr-OH
Boc-HoTyr-OH. Alternative Names: Boc-L-HomoTyrosine; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-(4-hydroxyphenyl)butanoic acid. Grades: ≥ 95%. CAS No. 198473-94-8. Molecular formula: C15H21NO5. Mole weight: 295.3.
Boc-Ile-Glu-Gly-Arg-AMC
Boc-IEGR-AMC is a specific, highly fluorogenic substrate for clotting enzyme factor Xa (coagulation factor Xa). Alternative Names: Boc-ile-glu-gly-arg-7-amido-4-methylcoumarin; 7-(Nalpha-tert-butyloxycarbonyl-L-isoleucyl-L-glutamylglycyl-L-arginyl)amino-4-methylcoumarin. Grades: >97%. CAS No. 65147-06-0. Molecular formula: C34H50N8O10. Mole weight: 730.81.
Boc-L-alanine
Boc-L-alanine. Alternative Names: Boc-L-Ala-OH; N-(tert-Butoxycarbonyl)-L-alanine. Grades: ≥ 99.5% (Chiral HPLC). CAS No. 15761-38-3. Molecular formula: C8H15NO4. Mole weight: 189.20.
Boc-L-aspartic acid α-tert-butyl ester
Boc-L-aspartic acid α-tert-butyl ester. Uses: An aspartic acid derivative used in stereoselective synthesis. Alternative Names: Boc-L-Asp-OtBu; (S)-4-(tert-butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid. Grades: ≥ 98% (HPLC). CAS No. 34582-32-6. Molecular formula: C13H23NO6. Mole weight: 289.40.
Boc-L-aspartic acid β-methyl ester
Boc-L-aspartic acid β-methyl ester is used to prepare isoxazoline glycoprotein IIb / IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. Alternative Names: Boc-L-Asp(OMe)-OH; Boc-Asp(OMe)-OH; Boc-L-aspartic acid 4-methyl ester; (S)-2-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid; boc-asp(ome)-oh dcha; (S)-2-((Boc)amino)-4-methoxy-4-oxobutanoic acid; (2S)-2-([(TERT-BUTOXY)CARBONYL]AMINO)-4-METHOXY-4-OXOBUTANOIC ACID; (2S)-2-[(tert-butoxy)carbonylamino]-3-(methoxycarbonyl)propanoic acid. Grades: ≥ 99% (HPLC). CAS No. 59768-74-0. Molecular formula: C10H17NO7. Mole weight: 247.25.
Boc-L-beta-homoalanine, a noteworthy derivative of beta-homoalanine, serves as an essential constituent in the production of peptides and mimics. Its effectivity as a medicinal substance, especially with reference to treating devastating afflictions like Parkinson's, Alzheimer's, and multiple sclerosis, has been the focal point of discussion in relevant studies. Alternative Names: (S)-3-((tert-Butoxycarbonyl)amino)butanoic acid; Boc-beta-HoAla-OH; Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3S)-. Grades: 95%. CAS No. 158851-30-0. Molecular formula: C9H17NO4. Mole weight: 203.24.
Boc-L-citrulline
Boc-L-citrulline. Alternative Names: Boc-L-Cit-OH; (S)-2-Boc-amino-5-ureidopentanoic acid; Boc-L-Orn(carbamoyl)-OH; Boc L Cit OH. Grades: ≥ 98% (TLC). CAS No. 45234-13-7. Molecular formula: C11H21N3O5. Mole weight: 275.30.
Boc-L-cysteine
Boc-L-cysteine. Alternative Names: Boc-L-Cys-OH; N-tert-Butyloxycarbonylcysteine. Grades: 98.5-100.5% (Assay by titration). CAS No. 20887-95-0. Molecular formula: C8H15NO4S. Mole weight: 221.30.
Boc-L-glutamic acid α-tert-butyl ester
Boc-L-glutamic acid α-tert-butyl ester. Alternative Names: Boc-L-Glu-OtBu. Grades: ≥ 98% (HPLC). CAS No. 24277-39-2. Molecular formula: C14H25NO6. Mole weight: 303.36.
Boc-L-methionine. Alternative Names: Boc-L-Met-OH; N-(tert-Butoxycarbonyl)-L-methionine. Grades: ≥ 99% (HPLC). CAS No. 2488-15-5. Molecular formula: C10H19NO4S. Mole weight: 249.30.
Boc-L-phenylalanine Merrifield resin
Pre-loaded resins for solid phase peptide and organic synthesis. Alternative Names: Boc-L-Phe-Merrifield resin.
Boc-L-proline
N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir which nhibits the HCV protein NS5A. Daclatasvir can be used as a drug candidate for the treatment of hepatitis C (HCV). Alternative Names: Boc-L-Pro-OH; (S)-Boc-pyrrolidine-2-carboxylic acid; N-(tert-Butoxycarbonyl)-L-proline. Grades: ≥ 98% (HPLC). CAS No. 15761-39-4. Molecular formula: C10H17NO4. Mole weight: 215.30.
Boc-L-serine
Starting material for the synthesis of various a-amino acids via the b-lactone. Alternative Names: Boc-L-Ser-OH; Boc-L-β-Hydroxyalanine; (S)-Boc-2-amino-3-hydroxypropionic acid; N-(tert-Butoxycarbonyl)-L-serine. Grades: ≥ 98% (HPLC). CAS No. 3262-72-4. Molecular formula: C8H15NO5. Mole weight: 205.22.
Boc-L-serine tert-butyl ester
Boc-L-serine t-butyl ester is a modified and protected amino acid used in peptide synthesis. Alternative Names: Boc-L-Ser-OtBu; Boc-L-β-hydroxyalanine tert-butyl ester; (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate. Grades: ≥ 98%. CAS No. 7738-22-9. Molecular formula: C12H23NO5. Mole weight: 261.32.
Boc-piperazine hydrochloride. Alternative Names: Boc-Piz HCl. Grades: ≥ 99% (HPLC). CAS No. 76535-74-5. Molecular formula: C9H18N2O2·HCl. Mole weight: 222.71.
Boc-PNA-A(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Alternative Names: Boc-A(Z)-Aeg-OH. Grades: 98%. CAS No. 149376-69-2. Molecular formula: C24H29N7O7. Mole weight: 527.54.
Boc-PNA-C(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Alternative Names: Boc-C(Z)-Aeg-OH; N-(2-(4-(((Benzyloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine. Grades: 95%. CAS No. 144564-94-3. Molecular formula: C23H29N5O8. Mole weight: 503.51.
Boc-PNA-G(Z)-OH
Boc-PNA-G(Z)-OH is a synthetic peptide nucleic acid (PNA) monomer with a guanine base. It features a Boc (tert-butyloxycarbonyl) protecting group and a Z (benzyloxycarbonyl) group, commonly used in the synthesis of PNA oligomers for research in molecular biology and genetics, particularly in the study of DNA and RNA binding. Alternative Names: N-((N2-(Benzyloxycarbonyl)guanine-9-yl)acetyl)-N-(2-Boc-aminoethyl)glycine; Boc-G(Z)-Aeg-OH; Glycine, N-[[1,6-dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-[1,6-Dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine. Grades: ≥97% by HPLC. CAS No. 169287-77-8. Molecular formula: C24H29N7O8. Mole weight: 543.54.
Boc-PNA-thioU(PMB)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Alternative Names: Boc-thioU(PMB)-OH. Grades: 98%. CAS No. 253438-99-2. Molecular formula: C23H30N4O7S. Mole weight: 506.57.
Boc-PNA-T-OH
Boc-PNA-T-OH is a thymine-containing peptide nucleic acid monomer that is protected with a Boc (tert-butyloxycarbonyl) group at the N-terminus. It has a free carboxyl group at the C-terminus, allowing for further chemical modifications or elongation during the synthesis of PNAs. This monomer is used in the synthesis of PNAs, which are designed to bind to complementary nucleic acid sequences with high specificity and stability, making them useful in genetic diagnostics, antisense therapies, and molecular biology research. Alternative Names: Boc-T-Aeg-OH; Glycine, N-[2-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; Glycine, N-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-(3,4-Dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine; Boc-PNA-U(5-Me)-OH. Grades: 98%. CAS No. 139166-80-6. Molecular formula: C16H24N4O7. Mole weight: 384.39.
Boc-PNA-U-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Grades: 98%. CAS No. 149500-74-3. Molecular formula: C15H22N4O7. Mole weight: 370.36.
Boc-S-3-nitro-2-pyridinesulfenyl-L-cysteine
Boc-S-3-nitro-2-pyridinesulfenyl-L-cysteine. Alternative Names: Boc-L-Cys(Npys)-OH; t-Butyloxycarbonyl-(S-(3-nitro-2-pyridinesulfenyl))cysteine. Grades: ≥ 98% (HPLC). CAS No. 76880-29-0. Molecular formula: C13H17N3O6S2. Mole weight: 375.43.