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CiproFloxacin hydrochloride monohydrate
A second generation fluoroquinolone antibiotic. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid Hydrochloride Monohydrate; Bay Q3939 Hydrochloride Monohydrate. Grades: ≥98.0%. CAS No. 86393-32-0. Molecular formula: C17H18FN3O3.HCl.H2O. Mole weight: 385.82.
Cirsimaritin
Cirsimaritin is purified from the herbs of Microtea debilis. Cirsimaritin has the potential use in patients with congestive heart failure that can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. Cirsimaritin inhibits the growth of tumor cells and induces mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), and it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner; support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. Alternative Names: Scrophulein; 4',5-Dihydroxy-6,7-dimethoxyflavone; 7-Methylcapillarisin. Grades: 98.0%. CAS No. 6601-62-3. Molecular formula: C17H14O6. Mole weight: 314.3.
cis-4-Heptenal-[d2]
cis-4-Heptenal-[d2]. Alternative Names: (4Z)-4-Heptenal-D2; (Z)-4-Heptenal-D2; (4Z)-Heptenal-D2; cis-4-Heptenal D2. Grades: > 98%. CAS No. 1335436-36-6. Molecular formula: C7H10D2O. Mole weight: 114.18.
Citalopram hydrobromide
Citalopram Hydrobromide is a serotonin (5-HT) uptake inhibitor used as an antidepressant. Alternative Names: Citalopram HBr; Cipramil; Celexa; 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobromide. Grades: >95%. CAS No. 59729-32-7. Molecular formula: C20H22BrFN2O. Mole weight: 405.31.
Citreorosein
Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells, it represents a potential therapeutic approach for the treatment of inflammatory diseases. Citreorosein attenuates degranulation and LTC 4 generation through the suppression of multiple step signaling and would be beneficial for the prevention of allergic inflammation. Bioassay directed isolation of C. nigricans leaf extract yielded anthraquinones emodin, citreorosein, and emodic acid and a flavonoid, luteolin, they can kill mosquito larvae Anopheles gambiaea adult B. tabaci, thus the extract of C. nigricans has the potential to be used as an organic approach to manage some of the the agricultural pests. Uses: Anti-inflammatory. Alternative Names: 1,3,8-Trihydroxy-6-hydroxymethylanthraquinone; 1,3,8-trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione; ω-Hydroxyemodin. Grades: >97%. CAS No. 481-73-2. Molecular formula: C15H10O6. Mole weight: 286.2.
Citromycetin
Citromycetin is produced by the strain of Citromyces sp. and Penicillum frequentans. Independently isolated and named from a number of different fungal species during the 1930s to 1950s; active against gram positive bacteria. Alternative Names: 4H,5H-Pyrano(3,2-c)(1)benzopyran-10-carboxylic acid, 8,9-dihydroxy-2-methyl-4-oxo-. Grades: >95% by HPLC. CAS No. 478-60-4. Molecular formula: C14H10O7. Mole weight: 290.22.
Citronellol-[d2]
An isotope analog of Citronellol. Citronellol is a kind of natural occurring acyclic monoterpenoid which can be found in citronella oils such as Cymbopogon nardus ((+)-citronellol), rose oils and Pelargonium geraniums ((-)-citronellol). Grades: ≥95%. CAS No. 76027-02-6. Molecular formula: C10H18D2O. Mole weight: 158.28.
Citropten
Citropten is a coumarin compound found in the peel of Citrus medica L. Alternative Names: 2H-1-Benzopyran-2-one, 5,7-dimethoxy-;5,7-dimethoxy-2h-1-benzopyran-2-on;5,7-Dimethoxy-2H-chromen-2-one. Grades: >98%. CAS No. 487-06-9. Molecular formula: C11H10O4. Mole weight: 206.2.
CL2A-Chimmitecan
CL2A-Chimmitecan is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: CL2A-Chimmitecan dichloroacetate salt. Molecular formula: C74H97N11O22.C2H2Cl2O2. Mole weight: 1621.58.
ClAc-Gly-OH
ClAc-Gly-OH. Alternative Names: Chloracetyl glycine(2-Chloro-acetylamino)-acetic acid. Grades: ≥ 99% (TLC). CAS No. 6319-96-6. Molecular formula: C4H6ClNO3. Mole weight: 151.55.
Cladosporin
It is produced by the strain of Cladosporium cladosporiodes. Cladosporin has the activity of weak resistance to gram-positive bacteria, tinea trichoderma, microspora, potato filaria and other fungi. Alternative Names: 3,4-Dihydro-6,8-dihydroxy-3-(6-methyltetrahydropyran-2-ylmethyl)isocoumarin; Asperentin; (R)-6,8-Dihydroxy-3-(((2R,6S)-6-methyltetrahydro-2H-pyran-2-yl)methyl)isochroman-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-[[(2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl]methyl]-, (3R)-; (3R)-3,4-Dihydro-6,8-dihydroxy-3-[[(2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl]methyl]-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-[(tetrahydro-6-methyl-2H-pyran-2-yl)methyl]-, [2R-[2α(R*),6β]]-. Grades: ≥95% by HPLC. CAS No. 35818-31-6. Molecular formula: C16H20O5. Mole weight: 292.33.
Clarithromycin
It is produced by the strain of erythromycin. Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. It prevents bacteria from growing by interfering with their protein synthesis and binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides. It has similar antimicrobial spectrum as erythromycin, but is more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. It also has bactericidal effect on certain strains, such as Haemophilus influenzae, Streptococcus pneumoniae and Neisseria gonorrhoeae. Uses: Anti-bacterial agents. Alternative Names: Biaxin; 6-O-Methylerythromycin; Klaricid; Abbott-56268; 6-O-Methylerythromycin A; A 56268; Abbott 56268; Antibiotic A 56268; Antibiotic TE 31; Clamicin; Claric; Claridar; Claris; Claritek; Clarith; Clarithro; Clathromycin; Crixan; CRIXAN OD; Fascar; Fromilid; Kelamycin; Klabax; Klacid; Klaribac; Klarimix; Klarithran MR; Macladin; Naxy; TE 031; Veclam; Zeclar. Grades: >98%. CAS No. 81103-11-9. Molecular formula: C38H69NO13. Mole weight: 747.95.
Clavulanate Lithium
A beta-lactamase inhibitor. It can irreversibly inactivate beta-lactamase enzymes of beta-lactam resistant microbes preventing them from breaking down beta-lactam antibiotics. Alternative Names: (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate Lithium; Clavulanic acid, lithium salt. Grades: ≥98%. CAS No. 61177-44-4. Molecular formula: C8H8LiNO5. Mole weight: 205.09.
Clavulanate Potassium (1:1 mixture with silicon dioxide)
Clavulanate Potassium is a semi-synthetic beta-lactamase inhibitor isolated from streptomyces. It contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. It is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. It is commonly combined with amoxicillin or ticarcillin to increase its effectiveness. Uses: Beta-lactamase inhibitors. Alternative Names: Amonate; MM-14151; MM14151. CAS No. 61177-45-5. Molecular formula: C8H8KNO5. Mole weight: 237.25.
Clavulanic acid
It is produced by the strain of Streptomyces clavuligerus. Clavulanic acid has a strong inhibition of β-lactamase activity, almost no antibacterial effect. Alternative Names: Acido clavulanico; Acide clavulanique; acidum clavulanicum; Clavulansaeure. Grades: 95%. CAS No. 58001-44-8. Molecular formula: C8H9NO5. Mole weight: 199.16.
Clavulanic Acid Methyl-[d3] Ester
Clavulanic Acid Methyl-[d3] Ester is the labelled form of Clavulanic Acid Methyl Ester. It is a substituted Clavulanic acid as a b-lactamase inhibitor. Alternative Names: (2R,3Z,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Methyl-d3 Ester; [2R-(2α,3Z,5α)]-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Methyl-d3 Ester; Methyl-d3 Clavulanate; Clavulanic Acid Methyl-d3 Ester. Grades: 96.3%; 99.7% atom D. CAS No. 1821757-56-5. Molecular formula: C9H8D3NO5. Mole weight: 216.21.
Clemastine fumarate
Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM. Uses: Anti-allergic agents. Alternative Names: Agasten; Tavist; Mecloprodine; (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate. Grades: >98%. CAS No. 14976-57-9. Molecular formula: C21H26ClNO.C4H4O4. Mole weight: 459.96.
Clevidipine butyrate
Clevidipine Butyrate is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure. Alternative Names: 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(1-Oxobutoxy)methyl] Ester; Clevelox; Cleviprex; H 324/38; rac-Clevidipine. Grades: 95%. CAS No. 167221-71-8. Molecular formula: C21H23Cl2NO6. Mole weight: 456.32.
Clindamycin
Clindamycin is produced by the strain of semi-synthetic lincomycin. The antibacterial spectrum of chloralincomycin is the same as that of Lincomycin, but its antibacterial activity is stronger, and its effect on anaerobic bacteria such as fragile Bacteroides is equivalent to 3-4 times of that of Lincomycin. It can be injected or administered orally, and oral absorption is obviously superior to lincomycin. Alternative Names: Clindamycin phosphate EP Impurity E; Dalacine; Chlolincocin; Dalacin C; 7-Chlorolincomycin. Grades: >98%. CAS No. 18323-44-9. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98.
Clindamycin 2-Phosphate
Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common drug used to treat topical acne and can be effective against some methicillin-resistant Staphylococcus aureus (MRSA) infections. An impurity of Clindamycin. Alternative Names: Methyl 7-Chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidine-carboxamido)-1-thio-L-threo-α-D-galactooctopyranoside 2-(Dihydrogen Phosphate); 7(S)-Chloro-7-deoxylincomycin 2-Phosphate; Cleocin T; Cleocin Phosphate; Clinadac; Clindagel; Clindesse; Clindets; Dalacin P; Dalacin T; NSC 618653. Grades: Content:≥ 758 μg/mg. CAS No. 24729-96-2. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96.
(+)-Cloprostenol isopropyl ester
(+)-Cloprostenol isopropyl ester is a derivative of cloprostenol which has been found to be a FP receptor agonist as well as a luteolytic agent and could be used commonly as a veterinary drug for its effect in terminating pregnancy. Alternative Names: (+)-Cloprostenol isopropyl ester; HE113833; LP014937; (5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; [1R-[1α(Z),2β(1E,3R*),3α,5α]]-7-[2-[4-(3-Chlorophenoxy)-3-hy. Grades: 98%. CAS No. 157283-66-4. Molecular formula: C25H35ClO6. Mole weight: 466.99.
Clorofene
Clorofene is an antibacterial agent used in pharmaceuticals and personal care products in home, hospital, and veterinary disinfectant preparations. Alternative Names: Phenol, 4-chloro-2-(phenylmethyl)-; Clorophene; 4-Chloro-2-(phenylmethyl)phenol; o-Cresol, 4-chloro-α-phenyl-; 2-Hydroxy-5-chlorodiphenylmethane; 4-Chloro-2-benzylphenol; 4-Chloro-α-phenyl-o-cresol; 5-Chloro-2-hydroxydiphenylmethane; Bio-Clave; Chlorophene; Ketolin H; Neosabenyl; Nipacide BCP; Nipacide BCP 50; NSC 59989; o-Benzyl-p-chlorophenol; p-Chloro-o-benzylphenol; Preventol BP; Santophen; Santophen 1; Septiphene; Septol. Grades: ≥95%. CAS No. 120-32-1. Molecular formula: C13H11ClO. Mole weight: 218.68.
Clorsulon-[13C6]
Clorsulon-[13C6] is the labelled analogue of Clorsulon, which is a benzendisulfonamide derivative with fasciolicidal activity, used for the treatment of fasciola hepatica infections in calves and sheep. Alternative Names: Clorsulon-13C6; Clorsulon-(phenyl-13C6); 4-Amino-6-trichloroethenyl-1,3-benzene-13C6-disulfonamide; 4-Amino-6-(1,2,2-trichloroethenyl)-1,3-benzenedisulfonamide-13C6; Curatrem-13C6. Grades: 95% by HPLC; 98% atom 13C. CAS No. 1325559-24-7. Molecular formula: C2[13C]6H8Cl3N3O4S2. Mole weight: 386.61.
Clotrimazole
Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole. It is an antifungal medication commonly used in the treatment of fungal infections. Alternative Names: Lotrimin; Canesten; Mycelex; Clotrimazol; Mycosporin; Empecid; 1H-Imidazole, 1-[(2-chlorophenyl)diphenylmethyl]-; 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; Imidazole, 1-(o-chloro-α,α-diphenylbenzyl)-; 1-(o-Chlorophenyldiphenylmethyl)imidazole; 1-(o-Chlorotrityl)imidazole; Agisten; Canifug; Femcare; Locasten; Monobaycuten; NSC 257473; Pedisafe; Plimycol; Rimazole; Tibatin; Trimysten; Veltrim. Grades: >98%. CAS No. 23593-75-1. Molecular formula: C22H17ClN2. Mole weight: 344.84.
Cloxacillin Sodium Monohydrate
Cloxacillin Sodium Monohydrate is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. Uses: Anti-bacterial agents. Alternative Names: Cloxapen. Grades: >98%. CAS No. 7081-44-9. Molecular formula: C19H19ClN3NaO6S. Mole weight: 475.88.
Cochlioquinone B
It is the minor component of a bioactive pigment isolated from Bipolaris cynodontis and Cochliobolus miyabeanus. It is an NADH-ubiquinone reductase inhibitor. It is also a phytotoxic agent inhibiting root growth. It is closely related to cochlioquinone A which inhibits diacylglycerol acyltransferase and exhibits anti-angiogenic and nematocidal activity. It is an antagonist of the human chemokine receptor, CCR5, in HIV-1. Alternative Names: 20-De(acetyloxy)-11-deoxy-20-oxo-cochlioquinone A; 9-(1,3-Dimethyl-2-oxopentyl)-1,2,3,4aα,5,6,6a,12,12aα,12b-decahydro-3β-(1-hydroxy-1-methylethyl)-6aβ,12bβ-dimethyl-pyrano[3,2-a]xanthene-8,11-dione Stereoisomer; (3R,4aR,6aR,12aR,12bR)-9-[(1S,3S)-1,3-Dimethyl-2-oxopentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethylpyrano[3,2-a]xanthene-8,11-dione. Grades: >99% by HPLC. CAS No. 32450-26-3. Molecular formula: C28H40O6. Mole weight: 472.61.
Coclaurine
Coclaurine is isolated from the root of Coptis chinensis Franch. Uses: Anti-hiv; hypotensive. Alternative Names: (1S)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxyisoquinolin-7-ol. Grades: 98%. CAS No. 486-39-5. Molecular formula: C17H19NO3. Mole weight: 285.3.
Coenzyme A
Coenzyme A is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. Coenzyme A plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. About 4% of cellular enzymes utilize CoA as a substrate. Alternative Names: CoASH; Coenzyme A (free acid); Depot-Zeel; Coenzyme ASH; 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}. CAS No. 85-61-0. Molecular formula: C21H36N7O16P3S. Mole weight: 767.53.
Coenzyme Q10
Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. Coenzyme Q10 is widely found in the mitochondria of the whole body. It has a stronger antioxidant function than vitamin C and vitamin E, can effectively remove free radicals, and has good anti-aging, whitening, and moisturizing functions. It can be widely used in anti-aging and wrinkle-removing, whitening and lightening spots, moisturizing and moisturizing, firming and tenderizing skin, sunscreen repair products, and it is compatible with lotion cream formula, gel formula, and water formula. Uses: Ingredient of health care products. Alternative Names: CoQ10; Ubiquinone-10; Ubidecarenone; COQ10; Vitamin Q; NSC 140665; (all-E)-2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; Bio-Quinone Q10; Cosmesome Q 10; Ensorb; Kaneka Q10; Kudesan. Grades: ≥98%. CAS No. 303-98-0. Molecular formula: C59H90O4. Mole weight: 863.34.
Coenzyme Q10-[d6]
Coenzyme Q10-[d6] is the labelled analogue of Coenzyme Q10. Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. Alternative Names: Coenzyme Q10-d6; Bio-Quinone Q10-d6; CoQ10-d6; Cosmesome Q 10-d6; Ensorb-d6; Kaneka Q10-d6; Kudesan-d6; Li-Q-Sorb-d6. Grades: 95% by HPLC; 95% atom D. CAS No. 1331655-96-9. Molecular formula: C59H84D6O4. Mole weight: 869.4.
Coformycin
Coformycin is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity. Alternative Names: (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol; (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. Grades: 98%. CAS No. 11033-22-0. Molecular formula: C11H16N4O5. Mole weight: 284.27.
COG 133
COG 1333 is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Alternative Names: COG133; COG-133; Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu. Grades: 98%. CAS No. 514200-66-9. Molecular formula: C97H181N37O19. Mole weight: 2169.73.
Colchicine
Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). It inhibits the growth of MCF-7 human breast carcinoma cells and has anti-inflammatory activity. Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Alternative Names: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; (-)-Colchicine; Colchineos; Colchisol; Colcin; Colsaloid; Condylon; NSC 757. Grades: >98%. CAS No. 64-86-8. Molecular formula: C22H25NO6. Mole weight: 399.44.
Colchicine-[13C,d3]
Colchicine-[13C,d3], is the labelled analogue of Colchicine. Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM). Colchicine can lower body temperature, inhibit the respiratory center, enhance the effect of sympathomimetic drugs, constrict blood vessels, and raise blood pressure. Alternative Names: Colchicine 13C D3. Grades: > 95%. Molecular formula: C21[13C]H22D3NO6. Mole weight: 403.44.
Colchicine EP Impurity C
This alkaloid has been isolated from a number of plants including Colchicum kesselringii, C. luteum Baker, and M. robusta Bge. Alternative Names: beta-Lumicolchicine; b-Lumi (-)-Colchicine; β-Lumicolchicine; (-)-β-Lumicolchicine; β-Lumi-(-)-colchicine; N-[(7S,7bR,10aS)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide. CAS No. 6901-13-9. Molecular formula: C22H25NO6. Mole weight: 399.44.
Colistin
It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram negative infections including pneumonia. Alternative Names: Polymyxin E; Colobreathe; Promixin; Colimycin M; Belcomycin; Colymycin; Torazin; N-[(1S)-3-amino-1-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide. Grades: >95% by HPLC. CAS No. 1066-17-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43.
Colistin sulfate
Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Alternative Names: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grades: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43.
Colominic acid sodium salt
Colominic acid sodium salt is an exquisite compound, used for studying bacterial infections evoked by Streptococcus pneumoniae and Haemophilus influenzae. Unveiling its remarkable antimicrobial activity, this compound emerges as a quintessential constituent within pharmaceutical formulations, including antibiotics and vaccines. Alternative Names: Poly[2,8-(N-acetylneuraminic acid sodium salt)]; Sodium colominate; Polysialic Acid Sodium Salt. CAS No. 70431-34-4. Molecular formula: (C11H16NNaO8)n.
Combretastatin A4
Combretastatin A4 is a stilbenoid isolated from Combretum caffrum. Combretastatin A4 was shown to inhibit tubulin polymerization (IC50 = 2.2 μM). It has demonstrable antineoplastic activity. Uses: Antineoplastic agents, phytogenic. Alternative Names: 1-(3,4,5-trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene. Grades: ≥95%. CAS No. 117048-59-6. Molecular formula: C18H20O5. Mole weight: 316.35.
Communic acid
Communic acid isolated from the branchs of Platycladus orientalis. It exhibits modulatory activity in potentiating antibiotic activity against effluxing strains. Uses: Cytotoxic activity; antimicrobial activity. Alternative Names: (1S,4aα)-Decahydro-1β-(3-methyl-2,4-pentadienyl)-2-methylene-5,8aβ-dimethylnaphthalene-5β-carboxylic acid. Grades: 93%. CAS No. 2761-77-5. Molecular formula: C20H30O2. Mole weight: 302.5.
COMU
COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Alternative Names: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grades: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27.
Concanamycin A
It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nmol/L), which is an important tool for biochemical research. Alternative Names: Folimycin; concanamycin a; Antibiotic X 4357 B; Antibiotic S-45A; X 4357B; (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propen-1-yl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one. Grades: 98%. CAS No. 80890-47-7. Molecular formula: C46H75NO14. Mole weight: 866.09.
Copalic acid
Copalic acid. CAS No. 24470-48-2. Molecular formula: C20H32O2.
Copeptin (human)
Copeptin (CT-ProAVP) initially produces the same amount of (Arg8)-Vasopressin (AVP), which has become a prognostic indicator for a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failure, and myocardial infarction. Alternative Names: H-Ala-Ser-Asp-Arg-Ser-Asn-Ala-Thr-Gln-Leu-Asp-Gly-Pro-Ala-Gly-Ala-Leu-Leu-Leu-Arg-Leu-Val-Gln-Leu-Ala-Gly-Ala-Pro-Glu-Pro-Phe-Glu-Pro-Ala-Gln-Pro-Asp-Ala-Tyr-OH; L-Alanyl-L-seryl-L-α-aspartyl-L-arginyl-L-seryl-L-asparaginyl-L-alanyl-L-threonyl-L-glutaminyl-L-leucyl-L-α-aspartylglycyl-L-prolyl-L-alanylglycyl-L-alanyl-L-leucyl-L-leucyl-L-leucyl-L-arginyl-L-leucyl-L-valyl-L-glutaminyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolyl-L-α-glutamyl-L-prolyl-L-phenylalanyl-L-α-glutamyl-L-prolyl-L-alanyl-L-glutaminyl-L-prolyl-L-α-aspartyl-L-alanyl-L-tyrosine; CT-ProAVP. Grades: ≥95%. CAS No. 78362-34-2. Molecular formula: C177H279N49O58. Mole weight: 4021.46.
Copper tripeptide 1
Copper tripeptide 1 is a naturally occurring tripeptide that was isolated from human albumin by LorenPickart in 1973. Copper tripeptide 1 can increase the production of collagen, elastin, proteoglycan, and glycosaminoglycan mRNA in fibroblasts. It is a natural regulator of multiple cellular pathways in skin regeneration. GHK-Cu stimulates the production of collagen and is used in anti-aging products. GHK-Cu also exhibits a therapeutic effect on hair loss. Alternative Names: GHK-Cu; Prezatide Copper; L-Lysine, N2-(N-glycyl-L-histidyl)-, copper complex; [Glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]copper; Copper, [N2-(N-glycyl-L-histidyl)-L-lysinato(2-)]-; Copper peptide GHK-Cu; Copper tripeptide 1; Copper tripeptide-1; Cu-Tripeptide-1; GHK Copper; GHK-Cu Tripeptide; Copper peptide; H-Gly-His-Lys-OH Copper; H-GHK-OH Copper. Grades: >95%. CAS No. 89030-95-5. Molecular formula: C14H22CuN6O4. Mole weight: 401.91.
Copper Tripeptide-3 hydrochloride
Copper Tripeptide-3 hydrochloride is a synthetic peptide that consists of the amino acids alanine, histidine, and lysine, with a copper ion (Cu) complexed to the lysine. AHK-Cu is valued for its role in promoting wound healing, collagen synthesis, and overall skin regeneration. It is often used in anti-aging skincare products due to its ability to support the skin's natural repair processes and improve skin elasticity. Alternative Names: [L-Alanyl-kN-L-histidyl-kN,kN3-L-lysinato(2-)]copper monohydrochloride; Copper, [L-alanyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-, monohydrochloride; (Alanyl-histidyl-lysine)copper(II) hydrochloride; AHK-Cu.HCl; L-Alanyl-L-histidyl-L-lysine-copper(II) complex hydrochloride; Ala-His-{Lys-Cu}.HCl; AH-{Lys-Cu}.HCl. Grades: ≥95%. CAS No. 682809-81-0. Molecular formula: C15H25ClCuN6O4. Mole weight: 452.40.
Coprogen
Coprogen. Alternative Names: iron(III)-coprogen; ferric coprogen. CAS No. 31418-71-0. Molecular formula: C35H53FeN6O13. Mole weight: 821.67.
Corchoionoside C is isolated from the herbs of Polygonum hydropiper. It showed inhibition of osteoclast formation with no affect on BMM cell viability. Uses: Anti-allergic and ant-ihistaminic effects. Alternative Names: (2S,3E)-4-[(1S)-1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl ]-3-buten-2-yl β-D-glucopyranoside. Grades: 95.5%. CAS No. 185414-25-9. Molecular formula: C19H30O8. Mole weight: 386.4.
Cordycepin
It is produced by the strain of Cordyceps militaris and Aspergillus niaulans. Cordycepin can inhibit RNA biosynthesis and has anti-gram-positive and mycobacterium activities. Cordycepin has attracted much attention from scholars in the fields of anti-aging, health care, and new drug development. Uses: Anti-metastatic. Alternative Names: 3'-Deoxyadenosine; Cordycepine; 9-Cordyceposidoadenine; 9-(beta-D-3'-Deoxyribofuranosyl)adenine; 9-(3-Deoxy-β-D-ribofuranosyl)adenine; 9-(3-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine; NSC 401022; NSC 63984. Grades: ≥ 97%. CAS No. 73-03-0. Molecular formula: C10H13N5O3. Mole weight: 251.24.
Cornexistin
It is produced by the strain of Paecilomyces variotii SANK 21086. It has the activity of removing annual weeds (0.5 kg/he) and has no antibacterial effect. Alternative Names: 14-Dihydroxycornestin; (4R,5S,8S,9Z)-9-ethylidene-5,8-dihydroxy-4-propyl-4,5,7,8,9,10-hexahydro-1H-cyclonona[c]furan-1,3,6-trione. CAS No. 123068-35-9. Molecular formula: C16H20O6. Mole weight: 308.33.
Coronatine
It is produced by the strain of Pseudomonas coronafaciens, P. glycinea. It is a metabolite that is toxic to plants. Alternative Names: 2-Ethyl-1-{[(6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydro-1H-inden-4-yl)(hydroxy)methylidene]amino}cyclopropane-1-carboxylic acid; (+)-coronatine. Grades: ≥95%. CAS No. 62251-96-1. Molecular formula: C18H25NO4. Mole weight: 319.40.
Coronopilin
Coronopilin is a sesquiterpene lactone. Alternative Names: 10αH-Ambros-11(13)-en-12-oic acid, 1,6β-dihydroxy-4-oxo-, γ-lactone (8CI). CAS No. 2571-81-5. Molecular formula: C15H20O4. Mole weight: 264.32.
Corticosterone-[2,2,4,6,6,17A,21,21-d8]
Corticosterone-d8 is a labelled Corticosterone. Alternative Names: corticosterone 2,2,4,6,6,17A,21,21-D8. Grades: 98% by CP; 98% atom D. CAS No. 1271728-07-4. Molecular formula: C21H22D8O4. Mole weight: 354.51.
Cortistatin 14 (mouse, rat)
Cortistatin-14 is an endogenous neuropeptide expressed in the cortex and hippocampus. Alternative Names: Cortistatin-14; H-PRO-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-SER-SER-CYS-LYS-OH; CST-14; CST-14 (RAT). Grades: 98%. CAS No. 186901-48-4. Molecular formula: C81H113N19O19S2. Mole weight: 1721.01.
Corynoxine
Corynoxine is an enantiomer of Corynoxine B. It induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. By inducing autophagy, it promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. It also significantly decreased locomotor activity after oral administration to mice. Alternative Names: (16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester. Grades: >98%. CAS No. 6877-32-3. Molecular formula: C22H28N2O4. Mole weight: 384.47.
Cosmosiin
Cosmosiin also called Apigenin 7-O-glucoside, is a natural flavonoid found in the flowers of Cosmos bipinnatus. Cosmosiin exhibits the activities of anti-HIV, anti-proliferative and antioxidant, the compound may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Uses: Anti-proliferative; antioxidant; anti-hiv. Alternative Names: Apigenin 7-O-glucoside. Grades: >98%. CAS No. 578-74-5. Molecular formula: C21H20O10. Mole weight: 432.39.
Costunolide
Costunolide, a natural sesquiterpene compound with multiple biological activities, inhibits FPTase with IC50 of 20 μM, and also inhibits telomerase with IC50 of 65-90 μM. Uses: Anti-inflammatory and anti-oxidant. Alternative Names: CCRIS 6754; NSC 106404; CCRIS6754; NSC106404; CCRIS-6754; NSC-106404. Grades: >98%. CAS No. 553-21-9. Molecular formula: C15H20O2. Mole weight: 232.32.
Cotadutide
Cotadutide (MEDI 0382) is a subcutaneous GLP-1 and glucagon receptor dual agonist that can be used to treat type 2 diabetes. Alternative Names: MEDI 0382. CAS No. 1686108-82-6. Molecular formula: C167H252N42O55. Mole weight: 3728.03.
(±)-Cotinine-[d3]
(±)-Cotinine-[d3] is the labelled analogue of (±)-Cotinine, which is a major metabolite of nicotine in humans. Alternative Names: (±)-Cotinine-(methyl-d3); 1-(Methyl-d3)-5-(3-pyridinyl)-2-pyrrolidinone; rac-Cotinine-d3; (±)-Cotinine-d3. Grades: 99% by CP; 99% atom D. CAS No. 110952-70-0. Molecular formula: C10H9D3N2O. Mole weight: 179.23.
Coumarin
Coumarin is an edema modifier, known to stimulate macrophages to degrade extracellular albumin, allowing faster resorption of edematous fluids. It has anti-cancer, anti-inflammation, anti-virus and other pharmacological activities. Uses: Appetite-suppressing. Alternative Names: 2H-1-Benzopyran-2-one; 1,2-Benzopyrone; 5,6-Benzo-2-pyrone; Benzo-α-pyrone; Coumarinic Anhydride; NSC 8774; Rattex; cis-o-Coumarinic acid Lactone; o-Hydroxycinnamic acid lactone; 2H-Chromen-2-one; Coumarinic lactone; Kumarin. Grades: >98%. CAS No. 91-64-5. Molecular formula: C9H6O2. Mole weight: 146.14.
Coumarin 6
Coumarin 6 is a fluorescent dye that has been widely used in cell imaging and flow cytometry due to its excellent photostability. The cell membrane staining capabilities of Coumarin 6 not only facilitate complex visualization of cell morphology but also enable precise assessment of membrane integrity. This dye shows promising applications in drug delivery systems and bioimaging technology, helping to explore a variety of diseases and unravel the mystery of drug efficacy. Alternative Names: Coumarin 540;3-(2-benzothiazolyl)-7-(diethylamino)-2H-1-benzo-pyran-2-one; Coumarin 153; Coumarin 6. Grades: ≥99%. CAS No. 38215-36-0. Molecular formula: C20H18N2O2S. Mole weight: 350.43.
Coumermycin a1
Coumemycin A1 is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, IC50 70 μmol/L. It is produced by the strain of Streptomyces rishirensis, Str. spinichromogene and Str. Spinicoumarensis. It has anti-gram positive bacteria, negative bacteria, mycobacterium (weak) activity, cross-resistance with Novobiocin. Uses: Topoisomerase ii inhibitors. Alternative Names: coumermycin a1;COUMERMYCIN;4434-05-3;Coumamycin;Coumamycine;Coumamycinum;Cumamicina;Sugordomycin D-1a;Coumamycin [INN];Notomycin;Coumermycin (USAN);Coumermycin [USAN];Notomycin A1;PCH9QZ1IIH;CHEMBL4555272;NSC 107412;C05073;D02333;Sugordomycin D-la;[(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[[5-[[4-hydroxy-7-[(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-(5-methyl-1H-pyrrole-2-carbonyl)oxyoxan-2-yl. Grades: >98%. CAS No. 4434-5-3. Molecular formula: C55H59N5O20. Mole weight: 1110.08.
C-Reactive Protein (CRP) (77-82)
The fragment of C-Reactive Protein, a marker in the blood increasing in response to the inflammation in the body. Alternative Names: H-Val-Gly-Gly-Ser-Glu-Ile-OH. Grades: 98%. CAS No. 130349-01-8. Molecular formula: C23H40N6O10. Mole weight: 560.6.
Creatine-[13C3]
Creatine-[13C3], is the labelled analogue of Creatine. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer. Alternative Names: Creatine-13C3. Molecular formula: C[13C]3H9N3O2. Mole weight: 134.11.
c(RGDfK)
Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor. Grades: 98%. CAS No. 161552-03-0. Molecular formula: C27H41N9O7. Mole weight: 603.67.
Cryptofolione
Cryptofolione is purified from the fruits of Cryptocarya alba. Cryptofolione shows moderate cytotoxicity in both macrophages and T. cruzi amastigotes, and also displays a mild inhibitory effect on the promastigote form of Leishmania spp. Z-Cryptofolione and Cryptomoscatone D2 acts as highly efficacious inhibitors of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. Alternative Names: (2R)-2-[(1E,4S,6R,7E)-4,6-dihydroxy-8-phenylocta-1,7-dienyl]-2,3-dihydropyran-6-one. CAS No. 160098-78-2. Molecular formula: C19H22O4. Mole weight: 314.38.
Crystal violet-[d6]
Crystal violet-[d6] is a labelled analogue of Crystal violet, which is a triarylmethane dye. Alternative Names: Crystal violet-D6; 4,4'-Bis-(dimethylaminophenyl)-4''-dimethylamino-D6-phenyltritylium chloride; N-[4-[Bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methylmethanaminium Chloride-d6; Adergon-d6; Basic Violet 3-d6; Crystal Violet Chloride-d6; Gentersal-d6; Meroxyl-d6; Oxiuran-d6; Oxycolor-d6; Oxyozyl-d6; Violet CP-d6. Grades: 95% by HPLC; 98% atom D. CAS No. 1266676-01-0. Molecular formula: C25H24D6ClN3. Mole weight: 414.02.
C-telopeptide
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen and an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Alternative Names: H-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg-OH; L-alpha-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-alpha-aspartyl-glycyl-glycyl-L-arginine; (2S,11S,14S,17S,20S,23S)-14-((1H-imidazol-4-yl)methyl)-23-amino-20-(4-aminobutyl)-11-(carboxymethyl)-2-(3-guanidinopropyl)-17-methyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazahexacosane-1,26-dioic acid; CTX. Grades: ≥95%. CAS No. 162929-64-8. Molecular formula: C34H56N14O13. Mole weight: 868.89.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Alternative Names: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grades: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.