BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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DBCO-NHS ester
DBCO-NHS ester. Alternative Names: DBCO-NHS;N-Succinimidyl 4-[(5-Aza-3,4:7,8-dibenzocyclooct-1-yne)-5-yl]-4-oxobutyrate. Grades: > 99.0 %. CAS No. 1353016-71-3. Molecular formula: C23H18N2O5. Mole weight: 402.40.
DBCO-PEG4-amine
DBCO-PEG4-amine. Alternative Names: DBCO-PEG4-amine TFA salt;DBCO-NHCOPEG4-amine. Grades: >98.0%. CAS No. 1840886-10-3. Molecular formula: C29H37N3O6. Mole weight: 523.62.
DBCO-PEG4-GGFG-DX8951
DBCO-PEG4-GGFG-DX8951 is a drug-linker conjugate for ADC by using DX8951 (Synonyms: Exatecan, a DNA topoisomerase I inhibitor), linked via DBCO-PEG4-GGFG. Alternative Names: DBCO-PEG4-GGFG-Exatecan. Molecular formula: C72H79FN10O17. Mole weight: 1375.48.
DBCO-PEG4-Val-Cit-PAB-MMAF
DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Grades: >98.0%. CAS No. 2244602-23-9. Molecular formula: C88H126N12O20. Mole weight: 1672.01.
DBCO-PEG4-Val-Cit-PAB-PNP
DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. Alternative Names: 4-((17S,20S)-1-(DBCO-Butanedicarboxylamino)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate. CAS No. 2226472-28-0. Molecular formula: C55H66N8O15. Mole weight: 1079.16.
DBCO-PEG4-vc-PAB-Duocarmycin SA
DBCO-PEG4-vc-PAB-Duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB. Molecular formula: C79H95ClN12O20. Mole weight: 1568.14.
DBCO-PEG4-vc-PAB-Duocarmycin TM
DBCO-PEG4-vc-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB. Molecular formula: C79H94ClN11O18. Mole weight: 1521.13.
DBCO-Peg4-VC-PAB-MMAE
DBCO-Peg4-VC-PAB-MMAE is a cytotoxin and linker conjugate widely used in ADCs. Alternative Names: DBCO-PEG4-VC-PAB-MMAE; DBCO-PEG4-Val-Cit-PAB-MMAE. CAS No. 2129164-91-4. Molecular formula: C88H128N12O19. Mole weight: 1658.03.
DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM
DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB-(PEG2). Molecular formula: C83H103ClN12O18. Mole weight: 1592.25.
DBCO-PEG8-VA-PAB-SG3199
DBCO-PEG8-VA-PAB-SG3199 is a drug-linker conjugate for ADC by using SG3199 (a PBD dimer,has a potently cytotoxic against cancer cell lines), linked via DBCO-PEG8-VA-PAB. Molecular formula: C87H109N9O22. Mole weight: 1632.87.
DBM(C6)-VC-PAB-MMAE is a thiol-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: L-Valine, N-[[[4-[[N-[6-(3,4-dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N-[[[4-[[N-[6-(3,4-Dibromo-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valine. CAS No. 1644228-55-6. Molecular formula: C68H103Br2N11O15. Mole weight: 1474.44.
D-Cellobiose-[13C12]
D-Cellobiose-[13C12] is the deuterium labelled form of D-Cellobiose, and D-Cellobiose is a disaccharide that consists of two β-glucose molecules linked by a β-1,4 glycosidic bond. It can be used as a substrate of β-glucosidase. Alternative Names: [UL-13C12]cellobiose; 4-O-beta-D-[UL-13C6]glucopyranosyl-D-[UL-13C6]glucose; cellobiose-U-13C12; beta-D-[1-13C]glucopyranosyl-(1-4)-D-[1-13C]glucose. Molecular formula: [13C]12H22O11. Mole weight: 354.20.
D-Cysteine
D-Cysteine is a strong inhibitor of Escherichia coli growth and also functions to provide inorganic sulfates for the sulfation of xenobiotics. D-Cysteine is a non-physiological isomer of L-Cysteine, and is not involved in protein or glutathione synthesis. Alternative Names: (S)-Cysteine; (S)-2-amino-3-mercaptopropanoic acid; D-Zystein; D-Amino-3-mercaptopropionic acid; D-Cys; (2S)-2-amino-3-mercaptopropanoic acid. Grades: ≥97%. CAS No. 921-01-7. Molecular formula: C3H7NO2S. Mole weight: 121.16.
D-Cystine
D-Cystine. Alternative Names: (H-D-Cys-OH)2; (S,S)-3,3'-Dithio-bis(2-aminopropionic acid). Grades: ≥ 99% (Assay). CAS No. 349-46-2. Molecular formula: C6H12N2O4S2. Mole weight: 240.30.
Deacetylanisomycin
It is an antitumor antibiotic produced by the strain of Streptomyces SA 3097. It is an effective inhibitor of protein synthesis and plant growth regulator. Alternative Names: (-)-Deacetylanisomycin; 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, (2R,3S,4S)-(-)-; Antibiotic SA 3097D1. Grades: >99% by HPLC. CAS No. 27958-06-1. Molecular formula: C12H17NO3. Mole weight: 223.27.
Deacetylnimbin
Deacetylnimbin is a natural triterpenoid found in the barks of Azadirachta indica, it shows significant insecticidal activity to Piers rapae L and Plutella xylostlla L. Uses: Insecticidal. Alternative Names: Methyl-2-(furan-3-yl)-5-hydroxy-10-(2-methoxy-2-oxoethyl)-1,6,9a,10a-tetram ethyl-9-oxo-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-2H-cyclopenta[b]naphtho[2,3-d]furan- 6-carboxylate;6-Deacetylnimbin. Grades: >95%. CAS No. 18609-16-0. Molecular formula: C28H34O8. Mole weight: 498.57.
Deamino-histidine
Deamino-histidine. Alternative Names: 3-(Imidazol-4-yl)propionic acid; Dihydrourocanic acid. Grades: ≥ 98% (HPLC). CAS No. 1074-59-5. Molecular formula: C6H8N2O2. Mole weight: 140.14.
Decursidate
Decursidate isolated from the roots of Peucedanum decursivum. Alternative Names: Decursidate; 272122-56-2; [(2S)-2-hydroxy-2-(4-hydroxyphenyl)ethyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate9317AFZINC14503461. Grades: > 95%. CAS No. 272122-56-2. Molecular formula: C18H18O6. Mole weight: 330.3.
Defensin
Defensin is an antibacterial peptide isolated from Bombus ignitus. Alternative Names: His-Ser-Ala-Cys-Ala-Ala-Asn-Cys-Leu-Ser-Met-Gly-Lys-Ala-Gly-Gly-Arg-Cys-Glu-Asn-Gly-Val-Cys-Leu-Cys-Arg.
Defensin HNP-2 (human)
Defensin HNP-2 (human). Alternative Names: Neutrophil Peptide-2; H-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH. Grades: 95%. CAS No. 120721-97-3. Molecular formula: C147H217N43O37S6. Mole weight: 3370.95.
Degarelix acetate
Degarelix is a synthetic gonadotropin-releasing hormone receptor (GNRHR) antagonist. It decreases tumor volume of Dunning R3327H prostate tumor flank implants in rats when administered at a dose of 1 mg/kg per month. Formulations containing degarelix have been used in the treatment of advanced prostate cancer. Alternative Names: Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2.CH3CO2H; N-acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-((S)-dihydroorotamido)-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetic acid; D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate (1:1); FE 200486; Gonax. Grades: ≥98%. CAS No. 934016-19-0. Molecular formula: C82H103ClN18O16.C2H4O2. Mole weight: 1692.31.
Deguelin
Deguelin is a naturally occurring rotenoid, is known to be an Akt inhibitor and to have an anti-tumor effect on several cancers. Uses: Anti-tumor,anti-cancer. Grades: 98%. CAS No. 522-17-8. Molecular formula: C23H22O6. Mole weight: 394.41718.
Dehydroabietic acid
Dehydroabietic acid is a diterpenoid found in Pinus sp. Alternative Names: Dehydroabietate; Abieta-8,11,13-trien-18-oic acid; Abietic acid, dehydro-. Grades: 97.0%. CAS No. 1740-19-8. Molecular formula: C20H28O2. Mole weight: 300.44.
Dehydroadynerigenin β-neritrioside
Dehydroadynerigenin beta-neritrioside is a natural steroid found in the herbs of Nerium oleander. Alternative Names: Dehydroadynerigenin beta-neritrioside. Grades: >95%. CAS No. 143212-60-6. Molecular formula: C42H62O17. Mole weight: 838.95.
Dehydroadynerigenin digitaloside
Dehydroadynerigenin digitaloside is a natural steroid found in the herbs of Nerium oleander. Grades: >95%. CAS No. 52628-62-3. Molecular formula: C30H42O8. Mole weight: 530.66.
Dehydrocorydaline
Dehydrocorydaline, an alkaloid derived from the tubers of Corydalis ambigua, with potential anti-tumor activity it significantly inhibits MCF-7 cell proliferation in a dose- dependent manner. Uses: Analgesia. Alternative Names: 2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium dehydrocorydalin dehydrocorydalin chloride dehydrocorydaline. Grades: >98%. CAS No. 30045-16-0. Molecular formula: C22H24NO4. Mole weight: 366.44.
Dehydrocostus lactone
Dehydrocostus lactone and CL from root of S. lappa have anti-colorectal cancer activities through inhibiting Wnt/β-catenin pathway. Uses: Anti-colorectal cancer. Alternative Names: EPILIGULYL OXIDE; DEHYDROCOSTUSLACTONE; DEHYDROCOSTUS LACTONE hplc; (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; DEHYDROCOSTUNOLIDE; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-; Costus lactone, dehydro-; tris(methylene)-,(3aS,6aR,9aR,9bS)-. Grades: >98%. CAS No. 477-43-0. Molecular formula: C15H18O2. Mole weight: 230.3.
Dehydrodiconiferyl alcohol
Dehydrodiconiferyl alcohol is purified from the stems of Cucurbita moschata. (+)-(2S,3R)-Dehydrodiconiferyl alcohol is an antioxidant, and has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction. Dehydrodiconiferyl alcohol also shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Alternative Names: 2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxy-1-propen-1-yl)-7-methoxy-3-benzofuranmethanol. Grades: 96.0%. CAS No. 4263-87-0. Molecular formula: C20H22O6. Mole weight: 358.39.
Dehydrotolvaptan
One of the impurities of Tolvaptan, which has been found to be a vasopressin V2 receptor antagonist and could probably be effective against hypertensive heart failure and could also be an effective renal protective agent. Alternative Names: 5-Dehydro Tolvaptan; N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide; 7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-Oxo-2,3,4,5-tetrahydro-1H-1-benzazepine. Grades: 98.0%. CAS No. 137973-76-3. Molecular formula: C26H23ClN2O3. Mole weight: 446.94.
Delafloxacin-[d5]
Delafloxacin-[d5] is an isotopic labelled Delafloxacin, a fluoroquinolone antibiotic that can be used in the treatment of acute bacterial skin and skin structure infections (ABSSSI). Alternative Names: Delafloxacin-d5; RX-3341-d5; WQ-3034-d5; ABT492-d5. Molecular formula: C18H7D5ClF3N4O4. Mole weight: 445.79.
delta2-Avermectin B1a
Δ2-Avermectin B1a is a degradation product produced by the reversible base-catalyzed isomerization of ivermectin B1a. It is less active than ivermectin against T. urticae (LC90s = 0.23 and 0.038 ppm, respectively). Alternative Names: Avermectin A1a, 2,3-didehydro-5-O-demethyl-3,4-dihydro-, (4S)-; Δ2-4(R)-avermectin B1a; Δ2-Avermectin B1a. Grades: >95% by HPLC. CAS No. 110415-68-4. Molecular formula: C48H72O14. Mole weight: 873.07.
Delta-2-Ivermectin B1a
An irreversible base degradation product of ivermectin found in animals treated with ivermectin and in the environment. It is an anthelmintic in animal health. Alternative Names: Δ2-Ivermectin B1a; Ivermectin B1a, delta2-. Grades: >95% by HPLC. Molecular formula: C48H74O14. Mole weight: 875.09.
(-)-delta-Cadinene
(-)-delta-Cadinene is a sesquiterpene found in a wide variety of essential oil-producing plants. Alternative Names: Naphthalene, 1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1R,8aS)-; Cadina-1(10),4-diene, (-)-; Naphthalene, 1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-, (1R-cis)-; (1R,8aS)-1,2,3,5,6,8a-Hexahydro-4,7-dimethyl-1-(1-methylethyl)naphthalene; (-)-δ-Cadinene. CAS No. 13061-82-0. Molecular formula: C15H24. Mole weight: 204.35.
(+)-delta-Cadinene
(+)-delta-Cadinene is a useful research chemical. Alternative Names: (1S-cis)-4,7-dimethyl-1,2,3,5,6,8a-hexa-hydro-1-(1-methylethyl)-naphthalene; (1S-cis)-4,7-dimethyl-1,2,3,5,6,8-hexahydro-1-(1-methylethyl)naphthalene; 1-Isopropyl-4,7-dimethyl-1,2,3,5,6,8a-hexahydronaphthalene; Cadina-1(10),4-diene. Grades: 50%. CAS No. 483-76-1. Molecular formula: C15H24. Mole weight: 204.35.
Deltamethrin-[d5] (Mixture of Diastereomers)
Deltamethrin-[d5] (Mixture of Diastereomers) is the labelled analogue of Deltamethrin. Deltamethrin, a synthetic pyrethroid insecticide, acts as a potent inhibitor of calcineurin (protein phosphatase 2B). Alternative Names: Decamethrin-d5; Esbecythrin-d5; Deltamethrin-d5 (Mixture of Diastereomers); (1R,3R)-3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic Acid (S)-cyano(3-phenoxyphenyl-d5)methyl Ester. Grades: ≥95%; ≥96% atom D. CAS No. 1217633-23-2. Molecular formula: C22H14D5Br2NO3. Mole weight: 510.23.
δ-Tocotrienol
δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase / mammalian target of rapamycin signaling. Alternative Names: [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol. Grades: 95%. CAS No. 25612-59-3. Molecular formula: C27H40O2. Mole weight: 396.60.
Demeclocycline
It is produced by the strain of Streptomuces aureofaciens var. 38-2-14. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Alternative Names: Demethylchlortetracycline; 6-Demethylchlotetracycline; DMCT; 7-Chloro-6-demethyltetracycline; Ledermycin; RP 10192; Antibiotic 38-2-14 A; Novotriclina; Perciclina; Sumaclina. Grades: >98% by HPLC. CAS No. 127-33-3. Molecular formula: C21H21ClN2O8. Mole weight: 464.85.
Demeclocycline hydrochloride
Demethylchlorotetracycline is an antibiotic produced by Streptomyces viridifaciens and Str. aureofaciens S-604. It has antibacterial and anti-insect activity. Alternative Names: Demethylchlortetracycline hydrochloride; Demethylchlorotetracycline hydrochloride. Grades: >98% by HPLC. CAS No. 64-73-3. Molecular formula: C21H22Cl2N2O8. Mole weight: 501.31.
Demethoxymatteucinol
Demethoxymatteucinol is a natural product found in Uvaria afzelii and Desmos chinensis. Alternative Names: 6,8-dimethylpinocembrin; (-)-Demethoxymatteucinol; 5,7-Dihydroxy-6,8-dimethylflavanone. Grades: 98%. CAS No. 56297-79-1. Molecular formula: C17H16O4. Mole weight: 284.31.
Deoxyarbutin
DeoxyArbutin is a reversible tyrosinase inhibitor, inhibiting tyrosinase activity with IC50 of 50 nM. Grades: >98%. CAS No. 53936-56-4. Molecular formula: C11H14O3. Mole weight: 194.23.
Deoxycholic acid
Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Deoxycholic acid is specifically responsible for activating the G-protein-coupled bile acid receptor TGR5, stimulating the thermogenic activity of brown adipose tissue (BAT). Uses: Hypotensive. Alternative Names: Cholanoic Acid; Desoxycholic acid; 3α,12α-dihydroxy-5β-cholanate; Deoxycholate; Cholerebic; Degalol; Droxolan; Pyrochol; 5β-cholanic acid-3α,12α-diol; 7-Deoxycholic acid; 5β-Deoxycholic Acid; NSC 8797; Septocholl; Ursodeoxycholic Acid EP Impurity E. Grades: 98%. CAS No. 83-44-3. Molecular formula: C24H40O4. Mole weight: 392.58.
Deoxycholic acid-[2,2,4,4-d4]
Deoxycholic acid-2,2,4,4-d4 is a deuterated compound and a deoxycholic acid. Alternative Names: 7-Deoxycholic acid,-2,2,4,4-d4; 3a,12a-Dihydroxy-5β-cholanic acid-2,2,4,4-d4; Desoxycholic acid-2,2,4,4-d4. Grades: 98% by CP; 98% atom D. CAS No. 112076-61-6. Molecular formula: C24H36D4O4. Mole weight: 396.60.
Deoxynivalenol
Deoxynivalenol is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects. It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity. Alternative Names: Vomitoxin; Dehydronivalenol; 4-Deoxynivalenol. Grades: ≥ 98%. CAS No. 51481-10-8. Molecular formula: C15H20O6. Mole weight: 296.319.
Deoxynojirimycin
Deoxynojirimycin inhibits mammalian glucosidase 1. As well, it inhibits intestinal and lysosmal alpha-glucosidases, beta-glucosidase from sweet almonds, pancreatic alpha-amylase and amyloglucosidase. Alternative Names: DNJ; 1-Deoxynojirimycin; 1,5-Dideoxy-1,5-imino-D-glucitol; Moranoline; 1-dNM; 2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol; 5-Amino-1,5-dideoxy-D-glucopyranose; Duvoglustat; Moranolin. Grades: 98%. CAS No. 19130-96-2. Molecular formula: C6H13NO4. Mole weight: 163.17.
Dermcidin-1L (human)
The protein dermcidin expressed in sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1). Dermcidin and naturally occurring DCD-1L fragments do not interfere with membrane permeability and bind to different surface molecules. DCD-1L stimulates keratinocytes to produce cytokines and chemokines such as TNF-α, IL-8, CXCL10 and CCL20. Alternative Names: DCD-1L (human); H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH. Grades: ≥95%. CAS No. 478898-18-9. Molecular formula: C210H359N57O71. Mole weight: 4818.50.
Derquantel
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection. Derquantel is an effective nematicide, which can act as a nicotinic acetylcholine receptor antagonist agent, causing flaccid paralysis and nematode repellent. Alternative Names: 2-Deoxoparaherquamide; 2-Deoxoparaherquamide A; 2-Desoxoparaherquamide A; PF 00520904; PNU 141962. Grades: >98% by HPLC. CAS No. 187865-22-1. Molecular formula: C28H37N3O4. Mole weight: 479.61.
Derrisisoflavone J
Derrisisoflavone J is a natural compound used in the research of various diseases. With potent anti-cancer properties, it targets specific cancer cells and inhibits their growth. Grades: 97.0%. CAS No. 2172624-67-6. Molecular formula: C22H22O6. Mole weight: 382.41.
Deruxtecan
Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC). Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide linker and a maleimide group. The maleimide group in Deruxtecan can react with antibody to form antibody-drug conguates (ADC) such as Trastuzumab deruxtecan (DS-8201a), which is a HER2-targeting antibody-drug conjugate. DS-8201a significantly suppressed tumor growth in an immunocompetent mouse model with human HER2-expressing CT26.WT (CT26.WThHER2) cells. DS-8201a is currently in clinical trials. Alternative Names: Deruxtecan Analog; Deruxtecan, Trastuzumab deruxtecan; DS-8201a; DS8201a; DS 8201a; Exatecan derivative; DX-8951 derivative; DX 8951; DX8951; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycyl-L-phenylalanyl-N-[(2-{[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino}-2-oxoethoxy)methyl]glycinamide. Grades: ≥95%. CAS No. 1599440-13-7. Molecular formula: C52H56FN9O13. Mole weight: 1034.05.
D-erythrose-[4-13C]
D-erythrose-[4-13C]. Alternative Names: D-erythrose 4-13C. Grades: 98% by CP; 99% atom 13C. CAS No. 90913-08-9. Molecular formula: C3[13C]H8O4. Mole weight: 121.10.
Des-Aib2-Retatrutide
Des-Aib2-Retatrutide.
Des-(α)MeLeu13-Retatrutide
Des-(α)MeLeu13-Retatrutide.
Des-Asp15-Retatrutide
Des-Asp15-Retatrutide.
Des-Asp9-Retatrutide
Des-Asp9-Retatrutide.
Descyclopropyl Abacavir hydrochloride
Descyclopropyl Abacavir hydrochloride. Alternative Names: 2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, hydrochloride (5:9), (1S-cis)-; Abacavir EP Impurity C hydrochloride; Abacavir USP Related Compound A hydrochloride; Abacavir Descyclopropyl Impurity; 6-Aminocarbovir hydrochloride; ((1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol hydrochloride (5:9). CAS No. 138233-46-2. Molecular formula: C55H79Cl9N30O5. Mole weight: 1559.49.
Des-Gln3-Retatrutide
Des-Gln3-Retatrutide.
Des-Glu28-Retatrutide
Des-Glu28-Retatrutide.
Des-Gly29-Gly30-Retatrutide
Des-Gly29-Gly30-Retatrutide.
Des-Gly4-Retatrutide
Des-Gly4-Retatrutide.
Des-Ile12-Retatrutide
Des-Ile12-Retatrutide.
Desisobutyrylfidaxomicin
A derivative of Fidaxomycin. Fidaxomycin is a natural macrocyclic antibiotic that inhibits RNA polymerase with selectivity for Gram-positive bacteria over Gram-negative bacteria. Alternative Names: OP 1118; Fidaxomicin Metabolite OP-1118; (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-beta-L-mannopyranosyl]oxy]methyl]-12-[(6-deoxy-5-C-methyl-beta-D-lyxo-hexopyranosyl)oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; OPT 1118; Des Iso Butyryl Fidaxomicin; Fidaxomicin Impurity 3. Grades: >95%. CAS No. 1030825-28-5. Molecular formula: C48H68Cl2O17. Mole weight: 987.95.
Des-Leu14-Retatrutide
Des-Leu14-Retatrutide.
Desloratadine-[3,3,5,5-d4]
One of the isotopic labelled form of Desloratadine, which is an active metabolite of Loratadine. Alternative Names: Desloratadine-d4; piperidinylidene-3,3,5,5-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 2713301-38-1. Molecular formula: C19H15D4ClN2. Mole weight: 314.85.
Des-Lys16-Retatrutide
Des-Lys16-Retatrutide.
(±)-Desmonofluono Voriconazole
(±)-Desmonofluono Voriconazole is an impurity of Voriconazole, which is an antifungal medication used to treat a number of fungal infections. Alternative Names: 4-Pyrimidineethanol, α-(2,4-difluorophenyl)-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (R*,S*)-; (R*,S*)-2-(2,4-difluorophenyl)-3-pyrimidin-4-yl-1-(1,2,4-triazol-1-yl)butan-2-ol; (+/-)-Desmonofluono Voriconazole; rac 5-Desfluoro Voriconazole; 5-Desfluoro voriconazole, (+/-)-; (R*,S*)-α-(2,4-Difluorophenyl)-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol. Grades: ≥95%. CAS No. 182369-73-9. Molecular formula: C16H15F2N5O. Mole weight: 331.33.