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Cyclosporin B
Cyclosporin B is a minor analogue of the cyclosporin complex produced by Trichoderma. An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Alternative Names: 7-L-Alaninecyclosporine A. Grades: ≥90% by HPLC. CAS No. 63775-95-1. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin C
A minor analogue of the cyclosporin complex produced by a number of fungal species, including trichoderma, tolypocladium, fusarium, nectria and acremonium. It has the immunosuppressant activity but has been much less extensively investigated than the major analogue, cyclosporin A. Cyclosporin C is a broad-spectrum antifungal agent against filamentous phytopathogenic fungi but no activity against bacteria or yeasts. Alternative Names: 7-L-Threoninecyclosporin A; WF 3484. Grades: ≥90% by HPLC. CAS No. 59787-61-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin D
Cyclosporin D is a group of nonpolar cyclic oligopeptides with immunosupppressant activity. Cyclosporin D is a minor analogue of the cyclosporin complex produced by Trichoderma. Alternative Names: Ciclosporin Impurity G; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]; [Val7]ciclosporin A; Ciclosporin D; Val2-cyclosporine; 7-L-Valinecyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; Cyclosporine D; cyclo[Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Val-Sar-N(Me)Leu-Val-N(Me)Leu]. Grades: ≥90% by HPLC. CAS No. 63775-96-2. Molecular formula: C63H113N11O12. Mole weight: 1216.64.
Cyclosporin E
Cyclosporin E is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: Cyclosporin A, 5-L-valine-; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl); 5-L-Valinecyclosporin A; (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-L-Val-). Grades: ≥90% by HPLC. CAS No. 63798-73-2. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin H
The minor analogues of the cyclosporin family have immunological activity because they do not bind to immunophilins. It is an inhibitor of phorbol ester that effectively promotes tumors on mouse skin, and effectively inhibits calcium / calmodulin-dependent phosphorylation of EF-2 in vitro. It is an effective and selective formyl peptide receptor antagonist and formyl peptide-induced superoxide formation inhibitor. Alternative Names: 5-(N-methyl-D-valine)cyclosporine A. Grades: 95%. CAS No. 83602-39-5. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Cyclosporin L
Cyclosporin L is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]. Grades: ≥95%. CAS No. 108027-39-0. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin L Related Compound 3
Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grades: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24.
Cyclosporin T
Cyclosporin T is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-L-Leu-N-methyl-L-Val-); Cyclosporin A, 4-L-leucine-; 4-L-Leucinecyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]. Grades: ≥90% by HPLC. CAS No. 108027-44-7. Molecular formula: C61H109N11O12. Mole weight: 1188.58.
Cyclosporin U
Cyclosporin U is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: Ciclosporin Impurity D; 1,11-Anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucine]; [Leu11]Ciclosporin A; Ciclosporin U; Ciclosporin EP Impurity D; 11-L-Leucine-Cyclosporin A; Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl); 11-L-Leucinecyclosporin A; Cyclosporine EP Impurity D; Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]. Grades: 95%. CAS No. 108027-45-8. Molecular formula: C61H109N11O12. Mole weight: 1188.61.
Cyclosporin V
Cyclosporin V is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Alternative Names: Ciclosporin Impurity E; 1,11-Anhydro[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-(2S)-2-aminobutanoic acid]; [Abu1]Ciclosporin A; Ciclosporin V; Cyclosporine V; Ciclosporin EP Impurity E; Cyclosporin A, 1-[(2S)-2-aminobutanoic acid]-; 1-[(2S)-2-Aminobutanoic acid]cyclosporin A; cyclo[Abu-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)-Abu-Sar-N(Me)Leu-Val-N(Me)Leu]; cyclo[(N-(((2S)-2-aminobutyryl)-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl)-(2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; 1-(L-2-Aminobutanoic acid)cyclosporin A; Cyclo[D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-2-aminobutanoyl]. Grades: ≥90% by HPLC. CAS No. 108027-46-9. Molecular formula: C63H113N11O12. Mole weight: 1216.63.
Cylindrospermopsin
It is produced by the strain of Cylindrospermopsis raciborskii. Cylindrospermopsin is a tricyclic uracil derivative which is a cyanobacterial toxin. And it targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 μM, respectively), leading to cell death. It has been proved to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 μM. Alternative Names: [2aS-[2aα,3α,4α,5aα,7β(S*)]]-6-[Hydroxy[2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; 6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione; Cylindrospermopsine. Grades: ≥95%. CAS No. 143545-90-8. Molecular formula: C15H21N5O7S. Mole weight: 415.43.
Cyproterone acetate
Cyproterone acetate is a synthetic derivative of 17-hydroxyprogesterone, and acts as an androgen receptor antagonist as well as a weak progesterone receptor agonist with weak progestational and glucocorticoid activity. Uses: Androgen antagonists; antineoplastic agents; contraceptive agents, male; progestational hormones, synthetic. Alternative Names: Androcur, Cyprostat,Cyproteron, Procur, Cyprone, Cyprohexal, Ciproterona, Cyproteronum, Neoproxil, Siterone. Grades: 0.98. CAS No. 427-51-0. Molecular formula: C24H29ClO4. Mole weight: 416.93766.
Cys-beta-Amyloid (1-42)
Cys-beta-Amyloid (1-42) is a mutant form of the protein beta-amyloid (Aβ) that contains cysteine. It's a major component of amyloid plaques in the brains of people with Alzheimer's disease. Alternative Names: H-Cys-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Molecular formula: C206H316N56O61S2. Mole weight: 4617.48.
Cys-glutathione-[13C3,15N]
Cys-glutathione-[13C3,15N] is the labelled analogue of Glutathione. Glutathione (GSH) is an endogenous antioxidant which plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), neutrophils in lung tissue and increase the level of serum Ca2+ and be useful for the treatment of ANP. Glutathione can be used not only as medicine, but also as a base material for functional foods. It is widely used in functional foods such as delaying aging, enhancing immunity, and anti-tumor. Alternative Names: [13C3,15N]-Cys-glutathione; [1,2,3-13C3,15N]-Cys-glutathione; γ-glutamyl[13C3,15N]cysteinylglycine. CAS No. 1028814-07-4. Molecular formula: C7[13C]3H17N2[15N]O6S. Mole weight: 311.29.
SV40 T-antigen homolog can induce nuclear transport. Alternative Names: SV40 Nuclear Transport Signal Peptide Analog. Grades: 95%. CAS No. 104914-40-1. Molecular formula: C60H104N20O15S. Mole weight: 1377.66.
Cysteamine hydrochloride
It has been shown to increase intracellular glutathione levels in cystinotic cells, thus restoring the altered redox state of the cells. It is an antioxidant and inhibitor of DMBA-induced tumors. Alternative Names: 2-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol hydrochloride; Bekaptan; CI-9148; β-Mercaptoethylamine. Grades: 95 %. CAS No. 156-57-0. Molecular formula: C2H8ClNS. Mole weight: 113.61.
Cysteine-Melittin
Cysteine-melittin is a synthetic peptide that is a derivative of melittin, the main component of bee venom. Cysteine-melittin has an extra cysteine residue added to the C-terminal end of melittin. Alternative Names: Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-Cys-NH2. Molecular formula: C134H234N40O32S. Mole weight: 2949.82.
Cytidine-[1'-13C]
Cytidine-[1'-13C] is the isotope labelled analogue of Cytidine (β-D-Cytidine), which is a pyrimidine nucleoside that is composed of the pyrimidine base cytosine attached to the sugar ribose. Alternative Names: 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone-1'-13C; 1-β-D-ribosylcytosine-1'-13C; 1-(β-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine-1'-13C; Cytosine Riboside-1'-13C; NSC 20258-1'-13C. Grades: 98% by CP; 99% atom 13C. CAS No. 201996-57-8. Molecular formula: C8[13C]N3O5. Mole weight: 244.21.
Cytisine
Cytisine is a nicotinic acetylcholine receptor (nAChR) agonist. It has been used medically to help with smoking cessation. Cytisine can be used in health products. Uses: Smoking cessation. Alternative Names: Baptitoxin; Citizin; HSDB 3560; HSDB3560; HSDB-3560; Laburnin; NSC 407282; NSC407282; NSC-407282; Sophorin; Cytisine; Cytisinicline; Baptitoxine; Sophorine; (-)-Cytisine; Laburnin. Grades: ≥ 98%. CAS No. 485-35-8. Molecular formula: C11H14N2O. Mole weight: 190.246.
Cytochalasin B
It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine B has immunosuppressive effects. Alternative Names: (7S,13E,16R,20R,21E)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione; (E,E)-(5R,9R,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione; NSC 107658; Phomin. Grades: >99% by HPLC. CAS No. 14930-96-2. Molecular formula: C29H37NO5. Mole weight: 479.61.
CYTOCHALASIN D
It is produced by the strain of Metarrhizium anisopliae, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Uses: Anti-hypertensive. Alternative Names: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione; (7S,13E,16S,18R,19E,21R)-[11]21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenylcytochalasa-6(12),13,19-triene-1,17-dione; (-)-Cytochalasin D; 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-; NSC 209835; Zygosporin A; Cytohalasin D; Lygosporin A. Grades: >98%. CAS No. 22144-77-0. Molecular formula: C30H37NO6. Mole weight: 507.62.
Cytosine-[13C,15N2]
Cytosine-[13C,15N2] is the labelled analogue of Cytosine. Cytosine is one of the four bases that participate in the biosynthesis of DNA or RNA. Alternative Names: Cytosine 13C,15N2; 4-Amino-1H-pyrimidin-2-one-13C,15N2; 4-Amino-2(1H)-pyrimidinone-13C,15N2; 4-Amino-2-hydroxypyrimidine-13C,15N2; 4-Aminouracil-13C,15N2; Cytosinimine-13C,15N2. Grades: ≥98%; ≥98% atom 13C; ≥98% atom 15N. CAS No. 181517-10-2. Molecular formula: C3[13C]H5N[15N]2O. Mole weight: 114.08.
D-[13C5]Xylose
D-[13C5]Xylose is a labeled analog of D-Xylose, which is used in diagnostic malabsorption tests as well as in the production of Furfural. CAS No. 1262683-58-8. Molecular formula: 13C5H10O5. Mole weight: 155.09.
Dabigatran etexilate-[d13]
One of the isotopic labelled form of Dabigatran Etexilate, which is a direct thrombin inhibitor and could be used as an oral anticoagulant agent. Alternative Names: ethyl 3-(2-(((4-(N-(((hexyl-d13)oxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate. Grades: 95% by HPLC; 98% atom D. Molecular formula: C34H28D13N7O5. Mole weight: 640.82.
Dacarbazine-[d6]
Dacarbazine-[d6] is the isotope labelled analog of Dacarbazine. Dacarbazine is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. Alternative Names: Dacarbazine D6; 5-[3,3-Di-(methyl-d3)-1-triazenyl]imidazole-4-carboxamide; DTIC-d6; DIC-d6. Grades: 95% by HPLC; 98% atom D. CAS No. 1185241-28-4. Molecular formula: C6H4D6N6O. Mole weight: 188.22.
Daidzein
Daidzein belongs to the group of isoflavones. Daidzein can be converted to its end metabolite S-equol in some humans based on the presence of certain intestinal bacteria. Based on several decades of research, S-equol has potential for significant health benefits. Daidzein is a natural compound found in the roots of Pueraria lobata (Willd.) Ohwi, it can be used in cosmetics material. Uses: Anti-inflammatory; anti-fibrotic. Alternative Names: 7-hydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one. Grades: >98%. CAS No. 486-66-8. Molecular formula: C15H10O4. Mole weight: 254.24.
Daidzein-[d4]
Daidzein-[d4], is the labelled analogue of Daidzein. Daidzein binds to estrogen receptor β but not ERα at concentrations up to 1 mM. And it is an inhibitor of carbonic anhydrase (CA) that is selective for carbonic CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively). Alternative Names: Daidzein D4. Grades: 98% (CP); 99% atom D. CAS No. 1219803-57-2. Molecular formula: C15H6D4O4. Mole weight: 258.26.
Daidzin
Daidzin is a natural organic compound in the class of phytochemicals known as isoflavones. Daidzin has shown the potential for the treatment of alcohol dependency (antidipsotropic) based on animal models. Daidzin has a significant antibacterial effect on Staphylococcus aureus and Escherichia coli. Estrogen-like effect, anti-osteoporosis, anti-estrogen activity in the treatment of menopausal syndrome, anti-hypoxic effect in the prevention and treatment of breast cancer and endometritis. Alternative Names: 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-; 7,4'-Dihydroxyisoflavone 7-glucoside; Daidzein 7-glucoside; Daidzein 7-O-glucoside; Daidzine; Daidzoside; NPI 031D; 3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one. Grades: >98%. CAS No. 552-66-9. Molecular formula: C21H20O9. Mole weight: 416.38.
(D-Ala18)-Liraglutide trifluoroacetate salt
(D-Ala18)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Alternative Names: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-D-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C172H265N43O51.C2HF3O2. Mole weight: 3865.21.
D-Ala18-Retatrutide
D-Ala18-Retatrutide.
D-Ala21-Retatrutide
D-Ala21-Retatrutide.
[D-Ala2]-Leucine enkephalin
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors. It inhibits the release of acetylcholine and inhibits muscle contraction. Alternative Names: L-Leucine, N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-; L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine; 1-5-(D-Ala2)-dynorphin; 2-D-Alanine-5-leucine-enkephalin; [D-Ala2]leucine-enkephalin; H-Tyr-D-Ala-Gly-Phe-Leu-OH; Leuphasyl; NSC 374895; Pentapeptide 18; Tyr-D-Ala-Gly-Phe-Leu; Tyr-D-Ala-Gly-Phe-Leu-OH; Tyrosyl-D-alanylglycylphenylalanylleucine. CAS No. 64963-01-5. Molecular formula: C29H39N5O7. Mole weight: 569.65.
D-Ala35-Retatrutide
D-Ala35-Retatrutide.
D-Ala-Leu-Lys-7-amido-4-methylcoumarin
D-Ala-Leu-Lys-7-amido-4-methylcoumarin is a sensitive and highly specific fluorogenic substrate for plasmin. Grades: 95%. CAS No. 104881-72-3. Molecular formula: C25H37N5O5. Mole weight: 487.59.
Dalargin is an endogenous opioid peptide leucine-encephalin. Alternative Names: (D-Ala2)-Leu-Enkephalin-Arg; H-Tyr-D-Ala-Gly-Phe-Leu-Arg-OH. Grades: 98%. CAS No. 81733-79-1. Molecular formula: C35H51N9O8. Mole weight: 725.83.
Dalbavancin
Dalbavancin is a semi-synthetic glycopeptide by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram-positive and multi-drug resistant isolates such as MRSA and MRSE. Alternative Names: dalbavancin B0; BI397. Grades: >98%. CAS No. 171500-79-1. Molecular formula: C88H100Cl2N10O28. Mole weight: 1816.69.
Dalbavancin-[d6]
Dalbavancin-[d6], is the labelled analogue of Dalbavancin. Dalbavancin is a novel second-generation lipoglycopeptide antibiotic medication. Alternative Names: Dalbavancin-d6. CAS No. 1126461-54-8. Molecular formula: C88H94D6Cl2N10O28. Mole weight: 1822.75.
Dalbergin
Dalbergin is an intriguing natural compound extracted from diverse Dalbergia species, used in studying diverse ailments, encompassing inflammatory disorders, cancer and cardiovascular diseases. Robust scientific investigations have elucidated its remarkable anti-inflammatory, anti-cancer and cardioprotective properties, establishing Dalbergin as a groundbreaking and promising molecule in the research of natural compound. Alternative Names: 2H-1-benzopyran-2-one, 6-hydroxy-7-methoxy-4-phenyl-; 6-Hydroxy-7-methoxy-4-phenyl-2H-chromen-2-on; 6-Hydroxy-7-méthoxy-4-phényl-2H-chromén-2-one; DALBERGIONE. Grades: >98%. CAS No. 482-83-7. Molecular formula: C16H12O4.
Dalbergioidin
Dalbergioidin is a flavonoid compound found in the roots of Parochetus communis. Dalbergioidin shows tyrosinase inhibitory activity. Alternative Names: 2',4',5,7-Tetrahydroxyisoflavanone. Grades: 95%. CAS No. 30368-42-4. Molecular formula: C15H12O6. Mole weight: 288.3.
Dalfopristin
A semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains. Alternative Names: Dalfopristinum. Grades: >98% by HPLC. CAS No. 112362-50-2. Molecular formula: C34H50N4O9S. Mole weight: 690.85.
D-Allo-Ile12-Retatrutide
D-Allo-Ile12-Retatrutide.
D-Allo-Ile23-Retatrutide
D-Allo-Ile23-Retatrutide.
D-Allose
D-Allose is a remarkable monosaccharide, aiding in the realm of cutting-edge biomedical research and progressive drug development in cancer. Alternative Names: b-D-Allose. Grades: 97.0%. CAS No. 2595-97-3. Molecular formula: C6H12O6. Mole weight: 180.16.
D-Allo-Thr5-Retatrutide
D-Allo-Thr5-Retatrutide.
D-allo-Thr(6)-Octreotide
D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Alternative Names: DPhe-Cys-Phe-DTrp-Lys-DaThr-Cys-Thr-ol(Cys2&Cys7 bridge); [6-D-allothreonine]octreotide; DPhe-CF-DTrp-K-DaThr-C-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity A; (D-Phe)-Cys-Phe-(D-Trp)-Lys-(Dallo-Thr)-Cys-Thr-Ol (Disulfide bond Cys2/Cys7); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide impurity A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grades: ≥95%. CAS No. 1546983-12-3. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Allo-Thr7-Retatrutide
D-Allo-Thr7-Retatrutide.
D-allo-Threoninol
D-allo-Threoninol. Alternative Names: D-allo-Thr-ol; (2S,3R)-2-Amino-1,3-butanediol; (2S,3R)-2-aminobutane-1,3-diol. Grades: ≥ 95% (NMR). CAS No. 44520-54-9. Molecular formula: C4H11NO2. Mole weight: 105.10.
D-(α)MeLeu13-Retatrutide
D-(α)MeLeu13-Retatrutide.
Damnacanthal
Damnacanthal is a natural compound isolated from the fruit of Morinda citrifolia Linn. Damnacanthal acts as a potent and selective inhibitor of p56lck tyrosine kinase. It inhibits p56lck autophosphorylation with IC50 of 17 nM. Alternative Names: 1-Methoxy-2-formyl-3-hydroxy-9,10-anthraquinone; 3-Hydroxy-1-methoxyanthraquinone-2-aldehyde. Grades: 98%. CAS No. 477-84-9. Molecular formula: C16H10O5. Mole weight: 282.25.
Dansyl-Ala-Arg-OH
Dansyl-Ala-Arg-OH is a fluorescent substrate of carboxypeptidase M, and its fluorescence intensity is the same as the cleavage product Dansyl-Ala-OH (λex = 340 nm; λem = 495 nm), the product has to be extracted with chloroform. The uncleaved substrate is still in the aqueous phase (acidic pH). Alternative Names: N-dansyl-L-alanyl-L-arginine; N-{[5-(Dimethylamino)-1-naphthyl]sulfonyl}-L-alanyl-L-arginine; L-Arginine, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-alanyl-; (S)-2-((S)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)propanamido)-5-guanidinopentanoic acid. Grades: 95%. CAS No. 87687-46-5. Molecular formula: C21H30N6O5S. Mole weight: 478.57.
Danthron
1,8-Dihydroxyanthraquinone, an anthraquinone derivative, could be widely used as antioxidant, dye intermediate and a raw material to synthesise sorts of products. Uses: 1,8-dihydroxyanthraquinone could be widely used as antioxidant, dye intermediate and a raw material to synthesise sorts of products. Alternative Names: danthron;1,8-Dihydroxyanthraquinone;117-10-2;Chrysazin;Dantron;Dorbane;Istizin;Antrapurol;Laxanthreen;Diaquone;Laxanorm;Altan;1,8-Dihydroxyanthracene-9,10-dione;Laxipurin;Zwitsalax;Danivac;Dionone;Duolax;Laxipur;9,10-Anthracenedione, 1,8-dihydroxy-;danthrone;Prugol;Roydan;1,8-Dihydroxy-9,10-anthraquinone;1,8-Dihydroxyanthrachinon;Usaf nd-59;Dioxyanthrachinonum;Chrysazine;Dantrone;Dorbanex;1,8-Dihy. Grades: ≥95%. CAS No. 117-10-2. Molecular formula: C14H8O4. Mole weight: 240.21.
Dapivirine-[d4]
Dapivirine-[d4], is the labelled analogue of Dapivirine. Dapivirine is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibiting a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Alternative Names: Dapivirine D4. Grades: > 98%. CAS No. 1309283-15-5. Molecular formula: C20H15D4N5. Mole weight: 333.42.
Dapsone-[13C12]
Dapsone-[13C12] is the labelled analogue of Dapsone. Dapsone is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. Alternative Names: Dapsone-13C12; DADPS-13C12; DDS-13C12; Avlosulfon-13C12; Croysulfone-13C12; Diphenasone-13C12; Disulone-13C12; Dumitone-13C12; Sulphadione-13C12; 4,4'-Sulfonylbisbenzeneamine-13C12; 1,1'-Sulfonylbis[4-aminobenzene]-13C12; NSC 6091-13C12; 4,4'-Diaminodiphenyl-13C12-sulfone. Grades: 95% by HPLC; 98% atom 13C. CAS No. 1632119-29-9. Molecular formula: [13C]12H12N2O2S. Mole weight: 260.21.
Daptomycin
Daptomycin is a lipopeptide antibiotic produced by the soil saprotroph Streptomyces roseosporus. It is used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Uses: Anti-bacterial agents. Alternative Names: LY 146032; LY-146032; LY146032; Cidecin; Cubicin. Grades: >95%. CAS No. 103060-53-3. Molecular formula: C72H101N17O26. Mole weight: 1620.69.
Daptomycin-[d5] Trifluoroacetate
Daptomycin-[d5] Trifluoroacetate is a labelled analogue of Daptomycin. Daptomycin is an antibiotic used for the treatment of infections caused by Gram-positive organisms. Alternative Names: Daptomycin D5 Trifluoroacetate; [D5]-Cubicin; Ly-146032-d5 Trifluoroacetic Salt; Cidecin-d5 Trifluoroacetic Salt; Cubicin-d5 Trifluoroacetic Salt; Daptomycin-d5 Trifluoroacetic Acid Salt. Grades: 95% by HPLC; 95% atom D. CAS No. 1356579-56-0. Molecular formula: C78H99D5F9N17O32. Mole weight: 1967.77.
D-arabinitol
D-arabinitol is a sugar alcohol isolated from the bark of Eucommia ulmoides Oliver. It can be formed by the reduction of either arabinose or lyxose. Alternative Names: D-Arabinitol. Grades: > 98%. CAS No. 488-82-4. Molecular formula: C5H12O5. Mole weight: 152.15.
D-Argininol
D-Argininol. Alternative Names: H-D-Arg-ol. CAS No. 1313054-61-3. Molecular formula: C6H16N4O. Mole weight: 160.20.
Darutoside
Darutoside is isolated from the herb of Siegesbeckia orientalis. It can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production. Alternative Names: Darutin. Grades: 97%. CAS No. 59219-65-7. Molecular formula: C26H44O8. Mole weight: 484.62.
Dasatinib
Dasatinib, also known as BMS-354825, is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these kinases. Apparently because of its less stringent binding affinity for the BCR-ABL kinase, dasatinib has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. SRC-family protein-tyrosine kinases interact with variety of cell-surface receptors and participate in intracellular signal transduction pathways; tumorigenic forms can occur through altered regulation or expression of the endogenous protein and by way of virally-encoded kinase genes. Alternative Names: BMS-354825; BMS354825; BMS354825. Grades: >98%. CAS No. 302962-49-8. Molecular formula: C22H26ClN7O2S. Mole weight: 488.01.
D-Asp15-Retatrutide
D-Asp15-Retatrutide.
D-Asp9-Retatrutide
D-Asp9-Retatrutide.
D-Aspartic acid
D-Aspartic acid is a kind of non-essential amino acid found in food sources and dietary supplements. It is an endogenous NMDA receptor agonist and has similar activity to the L-isomer. It is also a non-metabolizable substrate for EAA uptake systems. It adjusts melatonin synthesis in the pineal gland. It may be used as a therapeutic agent in the treatment of schizophrenia-related symptoms. Alternative Names: (-)-Aspartic Acid; (R)-Aspartic Acid; D-(-)-Aspartic Acid; 2-Aminobutanedioic Acid; NSC 97922; NSC97922; NSC-97922; (R)-(-)-Aminosuccinic acid; (R)-2-Aminosuccinic acid; D-Aminosuccinic acid. Grades: 97%. CAS No. 1783-96-6. Molecular formula: C4H7NO4. Mole weight: 133.10.
Datopotamab deruxtecan
Datopotamab deruxtecan is an antibody-drug conjugate consisting of a humanized anti-TROP2 IgG1 monoclonal antibody conjugated to a potent topoisomerase I inhibitor payload via a stable tetrapeptide-based cleavable linker. Alternative Names: DS-1062; DS-1062A; Dato-DXd. CAS No. 2238831-60-0.
Daunorubicin hydrochloride
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Uses: Adcs cytotoxin. Alternative Names: RP 13057 Hydrochloride; Daunomycin; RP13057 Hydrochloride; RP-13057 Hydrochloride; Rubidomycin hydrochloride. Grades: >98%. CAS No. 23541-50-6. Molecular formula: C27H30ClNO10. Mole weight: 563.98.
Daurichromenic acid
Daurichromenic acid, isolated from the herbs of Rhododendron dauricum, is a terpenophenol with potent anti-HIV activity. Uses: Anti-hiv activity. Alternative Names: Daurichromenic acid;82003-90-5;(S,E)-2-(4,8-Dimethylnona-3,7-dien-1-yl)-5-hydroxy-2,7-dimethyl-2H-chromene-6-carboxylic acid;(+)-Daurichromenic acid; Dauichromenic acid;(+)-Daurichromenic acid;CHEMBL1171643;HY-N3692;BDBM50537945;AKOS040761576;FS-9068;(2S)-2-[(3E)-4,8-dimethylnona-3,7-dienyl]-5-hydroxy-2,7-dimethylchromene-6-carboxylic acid;DA-72571;CS-0024072;(2S)-2-[(3E)-4,8-dimethylnona-3,7-dienyl]-5-hydroxy-2,7-dimethyl-chromene-6-carboxylic acid;(S)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-5-hydroxy-2,7-dimethyl-2H-1-benzopyran-6-carboxylic acid. Grades: 97%. CAS No. 82003-90-5. Molecular formula: C64H78N14O24. Mole weight: 1427.4.
DBCO-amine
DBCO-amine. Alternative Names: Azadibenzocyclooctyne-amine. Grades: 95 %. CAS No. 1255942-06-3. Molecular formula: C18H16N2O. Mole weight: 276.33.
DBCO-C6-acid
DBCO-C6-acid. Alternative Names: Azadibenzocyclooctyne acid; 6-(11,12-Didehydro-5,6-dihydrodibenzo[b,f]azocine-5-yl)-6-oxohexanoic acid. Grades: >95.0%. CAS No. 1425485-72-8. Molecular formula: C21H19NO3. Mole weight: 333.39.
DBCO-Maleimide
DBCO-Maleimide. Alternative Names: DBCO-Mal;Dibenzocyclooctyne-maleimide; Azadibenzocyclooctyne-maleimide. Grades: >98.0%(HPLC). CAS No. 1395786-30-7. Molecular formula: C25H21N3O4. Mole weight: 427.45.
DBCO-NH-PEG4-amine
DBCO-NH-PEG4-amine. Uses: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. in the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Alternative Names: DBCO-PEG4-NH2;DBCO-NHCO-PEG4-amine TFA salt;DBCO-PEG4-amine;Azadibenzocyclooctyne-PEG4 amine; DBCO-PEG4 amine. Grades: ≥95%. CAS No. 1255942-08-5. Molecular formula: C29H37N3O6. Mole weight: 523.62.