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Hippuryl-L-arginine
Hippuryl-L-arginine is a substrate for carboxypeptidase B and carboxypeptidase N. Alternative Names: Hippuryl-Arg; N-(Benzenecarbonyl)glycyl-L-Arginine; N2-(N-Benzoylglycyl)-L-arginine; L-Arginine,N-benzoylglycyl-. CAS No. 744-46-7. Molecular formula: C15H21N5O4. Mole weight: 335.36.
Histamine-[1-13C,1-15N] dihydrochloride is the labelled analogue of Histamine dihydrochloride. Histamine dihydrochloride is used as a medication for the treatment of relapsing acute myeloid leukemia (AML). Alternative Names: Histamine-1-13C,1-15N dihydrochloride. Grades: 95% (CP); 98% atom 15N; 99% atom 13C. Molecular formula: C4[13C]H9N2[15N].2HCl. Mole weight: 186.05.
Histidyl-asparagine
Histidyl-asparagine is a dipeptide composed of histidine and asparagine. CAS No. 158691-82-8. Molecular formula: C10H15N5O4. Mole weight: 269.26.
Histidyl-lysine
Histidyl-lysine. Alternative Names: L-histidyl-L-lysine. CAS No. 37700-85-9. Molecular formula: C12H21N5O3. Mole weight: 283.33.
Histidyl-proline
Histidyl-proline is a dipeptide formed from L-histidine and L-proline residues. Alternative Names: L-Histidyl-L-proline; His-pro. Grades: >95%. CAS No. 20930-58-9. Molecular formula: C11H16N4O3. Mole weight: 252.27.
HIV-1 TAT Protein Peptide
It is a cell-permeable peptide (CPP) derived from the HIV-1 tat protein transduction domain (PTD), which has been shown to promote the entry of nucleic acids into several cell types. Alternative Names: HIV-1 Tat Protein (47-57); H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; TAT (47-57); L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grades: 98%. CAS No. 191936-91-1. Molecular formula: C64H118N32O14. Mole weight: 1559.83.
H-Leu-His-OH
H-Leu-His-OH. Alternative Names: Leu-His; Leucyl-Histidine; L-leucyl-L-histidine; L-Leu-L-His. CAS No. 38062-72-5. Molecular formula: C12H20N4O3. Mole weight: 268.31.
H-Lys-Pro-OH has the potential as a very promising healing agent in ulcer therapy. Alternative Names: Lysylproline; Lys-pro; Lysyl-Proline; L-lysyl-L-proline; KP dipeptide; Lysine Proline dipeptide; L-Proline, L-lysyl-. CAS No. 52766-27-5. Molecular formula: C11H21N3O3. Mole weight: 243.30.
Homalomenol A
Homalomenol A is a natural sesquiterpenoid isolated from the roots of Homalomena aromatica. Alternative Names: 7(11)-Oppositene-1β,4β-diol. Grades: >96.0%. CAS No. 145400-03-9. Molecular formula: C15H26O2. Mole weight: 238.4.
Homoeriodictyol
Homoeriodictyol is a natural compound isolated from the herbs of Taxillus sutchuenensis. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells. Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, (2S)-; (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-, (S)-; Flavanone, 4',5,7-trihydroxy-3'-methoxy-; (-)-Homoeriodictyol; (S)-Homoeriodictyol; 4',5,7-Trihydroxy-3'-methoxyflavanone; 5,7,4'-Trihydroxy-3'-methoxyflavanone; Eriodictyol 3'-methyl ether; Eriodictyonone; Hersperetin. Grades: 98.0%. CAS No. 446-71-9. Molecular formula: C16H14O6. Mole weight: 302.28.
Homoglutathione
Homoglutathione. Alternative Names: L-gamma-glutamyl-L-cysteinyl-beta-alanine; 2-amino-4-({1-[(2-carboxyethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid. Grades: 95%. CAS No. 18710-27-5. Molecular formula: C11H19N3O6S. Mole weight: 321.35.
Homopterocarpin
Homopterocarpin is purified from the roots of Sophora tonkinensis. Homopterocarpin can inhibit (lower concentration) or kill (higher concntration) humans' liver cancer cells under the cultured condition. Homopterocarpin can contribute to the hepatoprotective and antioxidant potentials of P. erinaceus extract in acetaminophen-provoked hepatotoxicity. (-)-Homopterocarpin has active insect antifeedant against both S. litura and R. speratus and antimitotic effect. Alternative Names: Homopterocarpin isomer. Grades: 96.0%. CAS No. 606-91-7. Molecular formula: C17H16O4. Mole weight: 284.31.
Honokiol
Honokiol is a polyphenol found in the genus Magnolia. Honokiol acts as an Akt inhibitor and also inhibits NF-κB, displaying anti-inflammatory, antiangiogenic and antitumor properties. It results in inhibition of bone metastatic growth of human prostate cancer cells. Honokiol has obvious antioxidant and anti-aging effects, thus can be used in cosmetic material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products. Uses: Anti-inflammatory and anti-cancer agent. Alternative Names: Honokiol;35354-74-6;5,3'-Diallyl-2,4'-dihydroxybiphenyl;NSC 293100;3,5'-Diallyl-4,2'-dihydroxybiphenyl;3',5-Diallylbiphenyl-2,4'-diol;C18H18O2;3',5-diallyl-2,4'-biphenyldiol;CPD000387107;CHEMBL16901;2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol;CHEBI:5759;4-allyl-2-(3-allyl-4-hydroxy-phenyl)phenol;11513CCO0N;2-[4-hydroxy-3-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol;5,3'-Diallyl-biphe. Grades: ≥98%. CAS No.
(+)-Hopeaphenol
(+)-Hopeaphenol is a natural product found in Vitis chunganensis and Dipterocarpus grandiflorus. Alternative Names: [6,6'-Bibenzo[6,7]cyclohepta[1,2,3-cd]benzofuran]-4,4',8,8',10,10'-hexol, 1,1',6,6',7,7',11b,11'b-octahydro-1,1',7,7'-tetrakis(4-hydroxyphenyl)-, (1S,1'S,6R,6'R,7S,7'S,11bS,11'bS)-; (+)-Hopeaphenol; (1S,1'S,6R,6'R,7S,7'S,11bS,11b'S)-1,1',7,7'-Tetrakis(4-hydroxyphenyl)-1,1',6,6',7,7',11b,11b'-octahydro-6,6'-bi-2-oxadibenzo[cd,h]azulene-4,4',8,8',10,10'-hexol. Grades: ≥95%. CAS No. 388582-37-4. Molecular formula: C56H42O12. Mole weight: 906.94.
H-Phe(4-Ac)-OH HCl
H-Phe(4-Ac)-OH HCl, an essential chemical for a wide range of pharmaceutical and peptide synthesis, boasts exceptional adequacy as a constituent for drug production. This product serves as a key reagent as well as a fundamental building block in the synthesis of peptide-based medications. Medical professionals and researchers commonly employ H-Phe(4-Ac)-OH HCl as an effective measure in the treatment of chronic pain and inflammation arising due to a multitude of conditions, including but not limited to osteoarthritis and rheumatoid arthritis. Alternative Names: 4-Acetyl-L-phenylalanine Hydrochloride; 4-Acetylphenylalanine hydrochloride; (S)-3-(4-Acetylphenyl)-2-aminopropanoic acid HCl; p-Acetylphenylalanine hydrochloride. CAS No. 20299-31-4. Molecular formula: C11H14ClNO3. Mole weight: 243.68.
H-Phe-Ile-OH
H-Phe-Ile-OH. Alternative Names: Phe-Ile; phenylalanylisoleucine; Phenylalanyl-Isoleucine; FI dipeptide; L-Phe-L-Ile; Phenylalanine Isoleucine dipeptide. Grades: 95%. CAS No. 22951-94-6. Molecular formula: C15H22N2O3. Mole weight: 278.35.
H-Pro-NH2
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Alternative Names: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grades: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10.
HPV16 E7 86-93
HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Alternative Names: H-Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile-OH; L-threonyl-L-leucyl-glycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-L-isoleucine. Grades: ≥95%. CAS No. 160212-93-1. Molecular formula: C37H66N8O10S. Mole weight: 815.03.
H-SER-TYR-OH
H-SER-TYR-OH. Alternative Names: Ser-Tyr; L-seryl-L-tyrosine; Serinyltyrosine; SY dipeptide; L-Ser-L-Tyr; Serine Tyrosine dipeptide. CAS No. 21435-27-8. Molecular formula: C12H16N2O5. Mole weight: 268.27.
H-Trp(Boc)-OH. Alternative Names: 1-(t-Butoxycarbonyl)-L-tryptophan; (S)-2-Amino-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid; Nin-Boc-L-tryptophan. Grades: ≥ 99% (HPLC). CAS No. 146645-63-8. Molecular formula: C16H20N2O4. Mole weight: 304.35.
H-TRP-TYR-OH
H-TRP-TYR-OH. Alternative Names: Trp-tyr; Tryptophyl-tyrosine; Tryptophyltyrosine; L-Tryptophanyl-L-tyrosine; L-Trp-L-Tyr. CAS No. 19653-76-0. Molecular formula: C20H21N3O4. Mole weight: 367.40.
H-TYR-HIS-OH
H-TYR-HIS-OH. Alternative Names: Tyr-His; tyrosyl-histidine; L-tyrosyl-L-histidine; L-Histidine, L-tyrosyl-. CAS No. 3788-44-1. Molecular formula: C15H18N4O4. Mole weight: 318.33.
H-TYR-TRP-OH
H-TYR-TRP-OH. Alternative Names: Tyr-Trp; L-tyrosyl-L-tryptophan; L-Tyr-L-Trp-OH. Grades: 95%. CAS No. 60815-41-0. Molecular formula: C20H21N3O4. Mole weight: 367.40.
Humanin
Humanin. Alternative Names: Protein Humanin (human). Grades: ≥95%. CAS No. 330936-69-1. Molecular formula: C119H204N34O32S2. Mole weight: 2687.22.
Human neutrophil peptide-1
Human neutrophil peptide-1 is an antimicrobial peptide found in Homo sapiens (Human). It belongs to the alpha-defensin family and has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. Alternative Names: H-Ala-Cys(1)-Tyr-Cys(2)-Arg-Ile-Pro-Ala-Cys(3)-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys(2)-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys(3)-Cys(1)-OH; L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanyl-glycyl-L-alpha-glutamyl-L-arginyl-L-arginyl-L-tyrosyl-glycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-glycyl-L-arginyl-L-leucyl-L-tryptophyl-L-alanyl-L-phenylalanyl-L-cysteinyl-L-cysteine (2->30),(4->19),(9->29)-tris(disulfide); Human Defensin NP-1; alpha-Defensin-1; Defensin HNP-1 (human); HNP-1; Defensin human neutrophil peptide-1. Grades: >95%. CAS No. 99287-08-8. Molecular formula: C150H222N44O38S6. Mole weight: 3442.03.
Humantenine
Humantenine may be found in the roots of Gelsemium elegans. Alternative Names: Humantenine; 82375-29-9; (1R,2S,4S,7Z,8R,9S)-7-ethylidene-1'-methoxy-5-methylspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3'-indole]-2'-one; CHEMBL523399; HY-N4031. Grades: >98%. CAS No. 82375-29-9. Molecular formula: C21H26N2O3. Mole weight: 354.5.
Humulene epoxide II
Humulene epoxide II is a natural compound found in cannaband hops used for studying various diseases, including inflammation-related disorders and cancer. Alternative Names: (1R,4E,8E,11R)-4,7,7,11-Tetramethyl-12-oxabicyclo[9.1.0]dodeca-4,8-diene;6,7-Epoxy-2,9-humuladiene;(-)-Humulene epoxide II;12-Oxabicyclo[9.1.0]dodeca-3,7-diene, 1,5,5,8-tetramethyl-, (1R,3E,7E,11R)-;12-Oxabicyclo[9.1.0]dodeca-3,7-diene, 1,5,5,8-tetramethyl-, (E,E)-(1R,11R)-(-)-;12-Oxabicyclo[9.1.0]dodeca-3,7-diene, 1,5,5,8-tetramethyl-, [1R-(1R*,3E,7E,11R*)]-;Humulene 1,2-epoxide;Humulene 6,7-epoxide. CAS No. 19888-34-7. Molecular formula: C15H24O. Mole weight: 220.35.
Huperzine A
(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. Uses: Ingredient of health care products. Grades: >98%. CAS No. 102518-79-6. Molecular formula: C15H18N2O. Mole weight: 242.32.
Hyaluronic acid sodium
Hyaluronic Acid, Sodium Salt is the sodium salt form of Hyaluronic Acid. Hyaluronic acid is a mucopolysaccharide with high-viscosity traditionally extracted from rooster combs, but now it is mainly produced via streptococcal fermentation. Hyaluronic acid exerts physiological effects through skin and mucous membrane absorption, including anti-inflammatory, promoting cell growth and differentiation, promoting wound repair, preventing skin aging, and maintaining its finish. Bioactive hyaluronic acid can be used to make skin and mucous membrane sprays, masks, eye drops, mouthwash, oral and vaginal protectants, etc. It has a broad application prospect. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: Hyaluronic acid, sodium salt; Arthrease; Artz; Artz Dispo; Artzal; Chlamyhyaluronic acid sodium salt; Cosphaderm; Cristalhyal 1.0; Crystalhyal; Cystistat; Euflexxa; FCH SUS; FCH-SU; Fermatron; HA; HA-F; HA-Q; HA-Q 1; HA-QA; HE-QSE; Healon; Healon (polysaccharide); Healon GV; Healon V; Hi-Aqua; Hyalart; Hyalein; Hyalein Mini; Hyalgan; Hyalonano; Hyaloorigo; Hyaluronan sodium salt; Hyaluronate sodium; Hyaluronic acid LM; Hyaluronic acid sodium salt; Hyasol; Hyladerm; Hylartin; Hylo Comod; Jointex; Khionat; Kynex; Maruha; MucoUp; Nanuo HA; Neoviderm; Nidelon; Opegan; Orthovisc; Ostenil; Provisc; Provisk; Renovhy. CAS No. 9067-32-7. Molecular formula: (C14H22NNaO11)n.
Hydantocidin
Hydantocidin is a compound with herbicidal activity produced by Streptomyces hygroscopicus SANK 63584. Its weeding effect on monocotyledonous and dicotyledonous annual weeds is stronger than Bialaphos and similar to the commercial Glyphosate. Alternative Names: 6-Oxa-1,3-diazaspiro(4.4)nonane-2,4-dione, 8,9-dihydroxy-7-(hydroxymethyl)-, (5S-(5alpha,7alpha,8beta,9beta))-. CAS No. 130607-26-0. Molecular formula: C7H10N2O6. Mole weight: 218.16.
Hydrocortisone 21-Octanoate-[d15]
Hydrocortisone 21-Octanoate-[d15] is the labelled derivative of Hydrocortisone. Hydrocortisone is a corticosteroid compound that has a broad range of anti-inflammatory and immunosuppressive effects and thus widely used in therapy of skin wound. Hydrocortisone is also a glucocorticoid produced to increase the level of blood sugar and inhibit the immune system. Alternative Names: 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl octanoate-d15; Cortisol Octanoate-d15; Cortisol 21-Octanoate-d15; Hydrocortisone Octanoate-d15; Hydrocortisone 21-Octanoate-d15; (11β)-11,17-Dihydroxy-21-[(1-oxooctyl)oxy]pregn-4-ene-3,20-dione-d15. Grades: >95%. Molecular formula: C29H29D15O6. Mole weight: 503.76.
Hydrolyzed Fumonisin B1
Hydrolyzed Fumonisin B1 is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1. Hydrolyzed Fumonisin B1 can weakly inhibit ceramide synthase. Alternative Names: AP1 Metabolite; Aminopentol; Aminopentol formate salt; 2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol. Grades: ≥95%. CAS No. 145040-09-1. Molecular formula: C22H47NO5. Mole weight: 405.61.
Hydroxybutyl methyl cellulose
Hydroxybutyl methyl cellulose. Alternative Names: Hydroxybutyl methyl cellulose. Grades: 95%. CAS No. 9041-56-9. Molecular formula: C4H10O2?xCH4O?x. Mole weight: 1373.6536.
Hydroxycarbamide-[13C,15N2]
Hydroxycarbamide-[13C,15N2] is the labelled analogue of Hydroxy Urea. Hydroxy Urea is an antitumor agent that can inhibit ribonucleoside reductase and DNA replication. Hydroxy Urea has the potential to treat sickle cell anemia. Alternative Names: Hydroxycarbamide 13C 15N2; N-Hydroxyurea-13C,15N2; Biosupressin-13C,15N2; Carbamohydroxamic Acid-13C,15N2; Carbamoyl Oxime-13C,15N2; Cytodrox-13C,15N2. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. CAS No. 1246814-92-5. Molecular formula: [13C]H4[15N]2O2. Mole weight: 79.03.
(-)-Hydroxycitric acid
(-)-Hydroxycitrate is a potent competitive inhibitor of ATP citrate lyase, which inhibits fatty acid synthesis, lipogenesis, food intake and induced weight loss. Alternative Names: Garcinia acid. Grades: 95%. CAS No. 27750-10-3. Molecular formula: C6H8O8. Mole weight: 208.12.
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a biopolymer often used as a thickener and adhesive. Uses: ·used as adhesives, bonding aids, filling cement admixtures ·used as coatings and optical brightener additives, coating polymers, filter control additives ·used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier ·used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs. Alternative Names: Cellulose, 2-hydroxyethyl ether; Cellulose hydroxyethylate; 2-Hydroxyethyl cellulose; 2-Hydroxyethyl cellulose ether; Alcoramnosan; Cellulose hydroxyethyl ether; Hydroxyethyl cellulose ether; Hydroxyethyl ether cellulose; Hyetellose; Liporamnosan; Sanhec. CAS No. 9004-62-0.
Hydroxyfenbendazole-[d3]
Hydroxyfenbendazole-[d3], is the labelled analogue of Hydroxyfenbendazole, which is an impurity of fenbendazole. Alternative Names: [5-(4-Hydroxy-phenyl-sulfanyl)-1H-benzo-imidazol-2-yl]-carbamic acid methyl-D3 ester; Hydroxyfenbendazole-D3. Grades: 95% by HPLC; 98% atom D. CAS No. 1596803-40-5. Molecular formula: C15H10D3N3O3S. Mole weight: 318.37.
Hydroxyfenbendazole-[methyl-d3] monohydrate
Hydroxyfenbendazole-[methyl-d3] monohydrate is a labelled analogue of Hydroxyfenbendazole monohydrate, which is used as a radiolabelled internal standard. Alternative Names: N-[6-[(4-Hydroxyphenyl)thio]-1H-benzimidazol-2-yl]carbamic acid methyl-d3 ester monohydrate; Hydroxyfenbendazole-D3 hydrate. CAS No. 1596379-07-5. Molecular formula: C15H12D3N3O4S. Mole weight: 336.38.
Hydroxylamine-[15N] hydrochloride
Hydroxylamine-[15N] hydrochloride is the labelled analogue of Hydroxylamine Hydrochloride, which acts as a mild reducing agent in various organic and inorganic chemical reactions. Alternative Names: Hydroxylamine-(15)N HCl; Hydroxylamine chloride-15N. Grades: 98% by CP; 98% atom 15N. CAS No. 40711-48-6. Molecular formula: ClH4[15N]O. Mole weight: 70.48.
Hydroxylupanine
Hydroxypurine is an alkaloid isolated from L. lanatus. It is an inhibitor of ganglion transmission. Alternative Names: Jamaidine; Luparine, hydroxy-; Oxylupanine. Grades: >95% by HPLC. CAS No. 15358-48-2. Molecular formula: C15H24N2O2. Mole weight: 264.36.
Hydroxy Pioglitazone-[d5] (Major) (M-IV) (Mixture of Diastereomers)
A deuterated labelled form of Hydroxy Pioglitazone M-IV which is a metabolite of Pioglitazone, a PPARγ agonist used as an anti-diabetic drug. Alternative Names: 5-[[4-[2-[5-(1-Hydroxyethyl-d4)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione-D5. CAS No. 1189445-29-1. Molecular formula: C19H15D5N2O4S. Mole weight: 377.47.
In oral products, (hydroxypropyl)methyl cellulose is mainly used as a tablet binder, film coating agent and matrix for use in extended release tablet formulations. It is also used as a suspending agent and/or thickener in liquid oral dosage forms and topical preparations. It is also used in the manufacture of capsules, as an adhesive for plastic bandages and as a wetting agent for hard contact lenses. Alternative Names: Cellulose hydroxypropyl methyl ether; Hypromellose; Benecel MHPC; E464; hydroxypropyl methylcellulose; HPMC; hypromellosum; Methocel; methylcellulose propylene glycol ether; methyl hydroxypropylcellulose; Metolose; MHPC; Pharmacoat; Tylopur; Tylose MO. CAS No. 9004-65-3.
(Hydroxypropyl)methyl cellulose phthalate
(Hydroxypropyl)methyl cellulose phthalate is widely used in oral preparations as an enteric coating material for tablets or granules. Alternative Names: Cellulose, hydrogen 1,2-benzenedicarboxylate, 2-hydroxypropyl methyl ether; Hypromellose Phthalate; Cellulose phthalate hydroxypropyl methyl ether; HPMCP; Hydroxypropyl methylcellulose benzene-1,2-dicarboxylate; 2-Hydroxypropyl methylcellulose phthalate; Mantrocel HP-55; Methylhydroxypropylcellulose phthalate; 2-Hydroxypropyl methyl cellulose phthalate; Cellulose methyl 2-hydroxypropyl ether hydrogen phthalate ester; Glycidyl methacrylate-HPMCP copolymer. CAS No. 9050-31-1.
Hydroxysafflor yellow A
Hydroxysafflor yellow A has been demonstrated to prevent steroid-induced avascular necrosis of femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells adipogenic differentiation induced by steroid. Uses: Anti-tumor. Alternative Names: 2,5-Cyclohexadien-1-one, 2,4-di-β-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-; 2,4-Di-β-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-2,5-cyclohexadien-1-one; 2,5-Cyclohexadien-1-one, 2,4-di-β-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-; HSYA; Safflomin A. Grades: >98%. CAS No. 78281-02-4. Molecular formula: C27H32O16. Mole weight: 612.54.
Hydroxytyrosol
3,4-Dihydroxyphenyl ethanol is a phenolic component of olive oil that inhibits both 12-and 5-LO. The IC50 values for the inhibition of rat platelet 12-LO and rat neutrophil 5-LO are 4.2 and 13 μM, respectively. It does not inhibit, and may actually enhance, COX activity. 3,4-Dihydroxyphenyl ethanol also protects LDL from both biological and chemical oxidation, suggesting a potential mechanism for the protective effects of olive oil against atherosclerosis. 2-(3,4-Dihydroxyphenyl)ethanol is a natural compound found in the herbs of Canarium album, it has antioxidant properties thus can be used in cosmetics material. It is not only used in the synthesis of cardiovascular drugs, but also as a safe and efficient antioxidant, used in beauty products and health products, with anti-aging, anti-wrinkle, free radical scavenger, whitening, and freckle removal effects. Uses: Anti-oxidant. Alternative Names: DOPET; 3,4-Dihydroxyphenethyl alcohol; 3-Hydroxytyrosol; 2-(3,4-Dihydroxyphenyl)ethanol; 4-(2-Hydroxyethyl)-1,2-benzenediol; 2-(3,4-Dihydroxyphenyl)ethyl Alcohol; Homoprotocatechuyl Alcohol; β-(3,4-Dihydroxyphenyl)ethanol; 3,4-DHPEA; 3,4-Dihydroxyphenylethanol. Grades: ≥98%. CAS No. 10597-60-1. Molecular formula: C8H10O3. Mole weight: 154.16.
Hydroxy Tyrosol-[d4]
Hydroxy Tyrosol-[d4] is an isotopically labelled analogue of Hydroxy Tyrosol. a Tyrosol metabolite, a phenolic antioxidant. Alternative Names: 4-(2-Hydroxyethyl)-1,2-benzenediol-d4; 2-(3,4-Dihydroxyphenyl)ethanol-d4; 2-(3,4-Dihydroxyphenyl)ethyl Alcohol-d4; 3-Hydroxytyrosol-d4; Homoprotocatechuyl Alcohol-d4; β-(3,4-Dihydroxyphenyl)ethanol-d4; 3,4-DHPEA-d4. Grades: 95% by CP; 95% atom D. CAS No. 1330260-89-3. Molecular formula: C8H6D4O3. Mole weight: 158.19.
Hygromycin A
Hygromycin A is a natural antibiotic found in Streptomyces species. Hygromycin A selectively kills the bacteria that cause Lyme disease. Alternative Names: Totomycin; Antibiotic WS-1627B; 4-(5-Acetyl-3,4-dihydroxy-2-tetrahydrofuranyloxy)-3-hydroxy-alpha-methyl-N-(2,3,6-trihydroxy-4,5-methylendioxycyclohexyl)zimtsaeureamid. Grades: 95%. CAS No. 6379-56-2. Molecular formula: C23H29NO12. Mole weight: 511.48.
Hymeglusin
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Alternative Names: Hymeglusin;Antibiotic 1233A;29066-42-0;L-659,699;(2E,4E,7R)-11-[(2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid;2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-;Antibiotic F 244;(R,R)-Hymeglusin;L 659699;F 244;F-244;SCHEMBL613745;CHEMBL470269;GTPL5886;CHEBI:191049;DTXSID901318499;(R,2E,4E)-11-((2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl)-3,5,7-trimethylundeca-2,4-dienoic acid;HB3701;AKOS032946337;2,4-Undecadienoic acid, 11-(3-(hydroxymethyl)-4-oxo-2-oxetanyl)-3,5,7-trimethyl-, (2R-(2-alpha(2E,4E,7R*),3-beta))-;HY-117430;CS-0065979;G13092;J-017379;Q27078398;11-[3R-(hydroxymethyl)-4-oxo-2R-oxetanyl]-3,5,7R-trimethyl-2E,4E-undecadienoic acid. Grades: ≥95%. CAS No. 29066-42-0. Molecular formula: C29H28ClFN6O3. Mole weight: 563.
Hypericin
It is a natural antidepressant produced by the strain of Hypericium perforatum (plant extract). It is an anti-retroviral agent and protein kinaze-C inhibitor. Uses: Antineoplastic and antitumor. Alternative Names: Cyclo-Werol; Cyclosan; Hyperflav; Hypericum red; NSC 407313; Mycoporphyrin; 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone; 1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione. Grades: >98%. CAS No. 548-04-9. Molecular formula: C30H16O8. Mole weight: 504.45.
Hyperoside
Hyperoside is isolated from the herb of Hypericum perforatum L. It may be used as a candidate therapeutic agent for treating vascular inflammatory and occlusive vascular diseases, inhibiting the HMGB1 signaling pathway and activating the Nur77 receptor. Uses: Neuro-protective effect; anti-inflammatory and antioxidative effects. Alternative Names: 2-(3,4-Dihydroxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; Hyperin; 3,3',4',5,7-Pentahydroxyflavone 3-O-β-D-galactopyranoside; 3-D-Galactosylquercetin; 3-O-β-D-Galactopyranosyl quercetin; 3-O-β-D-galactopyranosylquercetin; Hyperosid; NSC 407304; Quercetin 3-galactoside; Quercetin 3-O-galactopyranoside; Quercetin 3-O-galactoside; Quercetin 3-O-β-D-galactopyranoside; Quercetin 3-O-β-D-galactoside; Quercetin 3-O-β-galactopyranoside; Quercetin 3-O-β-galactoside; Quercetin 3-β-D-galactoside; Quercetin 3-β-galactoside. Grades: ≥95%. CAS No. 482-36-0. Molecular formula: C21H20O12. Mole weight: 464.38.
Hypoxanthine
Hypoxanthine is a naturally occurring purine derivative. Alternative Names: 1,9-Dihydro-6H-purin-6-one; 3H-Purin-6-ol; 6-Hydroxy-1H-purine; 6-Hydroxypurine; 6-Oxopurine; Hypoxanthine enol; NSC 129419; NSC 14665; Purin-6-ol; Sarcine; Sarkin; Sarkine; USP Didanosine Related Compound A; 7H-Purin-6-ol; 1,7-Dihydro-6H-purin-6-one. Grades: ≥98% by HPLC. CAS No. 68-94-0. Molecular formula: C5H4N4O. Mole weight: 136.11.
Hypoxanthine-[13C2,15N]
One of the isotopic labelled form of Hypoxanthine, which is a purine compound, naturally existed, has been found to be a constituent of nucleic acids. Alternative Names: 1,9-Dihydro-6H-purin-6-one-13C2,15N; 3H-Purin-6-ol-13C2,15N; 6-Hydroxy-1H-purine-13C2,15N; 6-Hydroxypurine-13C2,15N; 6-Oxopurine-13C2,15N; Hypoxanthine Enol-13C2,15N; NSC 129419-13C2,15N. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. CAS No. 1246820-04-1. Molecular formula: C5H4N4O. Mole weight: 139.09.
Ibrexafungerp
Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Alternative Names: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-. Grades: 98%. CAS No. 1207753-03-4. Molecular formula: C44H67N5O4. Mole weight: 730.03.
Ibrexafungerp Citrate
Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Alternative Names: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). Grades: 98%. CAS No. 1965291-08-0. Molecular formula: C50H75N5O11. Mole weight: 922.17.
Ibrutinib
Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Alternative Names: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50.
Ibuprofen-[d4]
Ibuprofen-[d4] is the labelled form of Ibuprofen, which is a selective cyclooxygenase inhibitor. Alternative Names: 2-(4-Isobutylphenyl)propanoic-2,3,3,3-d4 acid; Ibuprofen D4; α-Methyl-4-(2-methylpropyl)benzeneacetic acid-d4; (4-Isobutylphenyl)-α-methylacetic acid-d4; (RS)-Ibuprofen-d4; (±)-2-(p-Isobutylphenyl)propionic acid-d4; (±)-Ibuprofen-d4; (±)-Ibuprophen-d4; 2-(p-Isobutylphenyl)propionic acid-d4; Actiprofen-d4. Grades: ≥98%; 98% atom D. Molecular formula: C13H14D4O2. Mole weight: 210.31.
Icariin
Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Alternative Names: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-b-D-glucopyranosyloxy-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. Grades: ≥ 98%. CAS No. 489-32-7. Molecular formula: C33H40O15. Mole weight: 676.66.
Icariside D2
Icariside D2 is isolated from the fruits of Annona glabra. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0±1.0?uM, and it induces apoptosis via alteration of expression of apoptosis-related proteins and decreased phosphorylation of AKT in HL-60 cells. Alternative Names: Icariside D2;38954-02-8;(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;IcarisideD2;CHEBI:182721;DTXSID001318054;HY-N7450;AKOS040761858;4-beta-D-Glucopyranosyloxybenzeneethanol;NCGC00385783-01;DA-54230;CS-0129180;G14608;4-(2-Hydroxyethyl)phenyl-beta-D-glucopyranoside;NCGC00385783-01_C14H20O7_4-(2-Hydroxyethyl)phenyl beta-D-glucopyranoside. Grades: 98.0%. CAS No. 38954-02-8. Molecular formula: C21H26N2O6. Mole weight: 402.4.
Icatibant Acetate
Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Alternative Names: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. Grades: ≥95%. CAS No. 138614-30-9. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base).
Idebenone
Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Alternative Names: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. Grades: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44.
Ile-His
Isoleucyl-histidine is a dipeptide composed of isoleucine and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Isoleucyl-Histidine; L-Ile-L-His. Grades: ≥95% by HPLC. CAS No. 97284-12-3. Molecular formula: C12H20N4O3. Mole weight: 268.31.
Ile-Pro-Pro
H-Ile-Pro-Pro-OH is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 μM. Alternative Names: H-Ile-Pro-Pro-OH; IPP, ACE-I Inhibitor. Grades: >98%. CAS No. 26001-32-1. Molecular formula: C16H27N3O4. Mole weight: 325.40.
Iloprost-[d4] (Major)
Iloprost-[d4] is a labelled analogue of Iloprost. A labelled synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. Alternative Names: (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid-d4; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane-d4; Ciloprost-d4; Endoprost-d4. Grades: 98% by CP; 98% atom D. CAS No. 1035094-10-0. Molecular formula: C22H28D4O4. Mole weight: 364.51.
Imatinib mesylate
Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Alternative Names: CGP-57148B; CGP 57148B; CGP57148B; Gleevec, Imatinib. Grades: >98%. CAS No. 220127-57-1. Molecular formula: C29H31N7O.CH4SO3. Mole weight: 589.71.