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Imazapyr
Imazapyr is a broad-spectrum herbicide used in weed control. Uses: Pesticide. Alternative Names: Imazapyr acid; Charper; Chopper. CAS No. 81334-34-1. Molecular formula: C13H15N3O3. Mole weight: 261.28.
Imidazole
An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Alternative Names: Ondansetron EP Impurity E; Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene; 1,3-Diazole; 3-Azapyrrole; Curezol SIZ; Glyoxalin; Imidazol; Imutex; Methanimidamide, N,N'-1,2-ethenediyl-; Miazole. Grades: ≥95%. CAS No. 288-32-4. Molecular formula: C3H4N2. Mole weight: 68.08.
Imipenem Monohydrate
Imipenem is an intravenous β-lactam antibiotic. It is the first member of the carbapenem class of antibiotics. Imipenem is discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species, but it is not active against MRSA. Uses: Anti-bacterial agents. Alternative Names: (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, monohydrate; N-Formimidoyl Thienamycin; MK-787; MK 787; MK787. Grades: 98%. CAS No. 74431-23-5. Molecular formula: C12H17N3O4S.H2O. Mole weight: 317.36.
Imperatorin
Imperatorin isolated from the root of Angelica dahurica Benth. et Hook. It can suppress multidrug-resistant human liver cancer growth in vivo by inducing Mcl-1 degradation. Imperatorin can be used in health products. Uses: Anti-hiv; anticonvulsant; anti-inflammatory; antimicrobial. Alternative Names: 9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one; Imperatorin; Pentosalen; Ammidin; Marmelosin. Grades: 98%. CAS No. 482-44-0. Molecular formula: C16H14O4. Mole weight: 270.3.
Indanomycin
Indanomycin is an antibiotic of the pyrroloketoindane class produced by Streptomyces sp. It is an unusual pyrollic ionophore that is active against gram-positive bacteria and insects. It has antihypertensive properties. It is a growth promoter in ruminants. Alternative Names: X-14547A; X 14547A; 2H-Pyran-2-acetic acid, 6-(1-ethyl-4-(1-ethyl-2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-alpha, 5-dimethyl-, (1S-(1-alpha,3-alpha,beta,4-beta,5-beta(1E(2S*(S*),5R*,6S*),3E),7a-alpha))-; Antibiotic X-14547A. Grades: >95% by HPLC. CAS No. 66513-28-8. Molecular formula: C31H43NO4. Mole weight: 493.68.
Indigo
Indigo, which can be found in the leaves of Isatis indigotica Fortune, participates in isolating oxygenase genes. Indigo carmine angiography provides visual information on foot perfusion. Uses: Anti-viral / antioxidant. Alternative Names: (2,2'-biindoline)-3,3'-dione; (2,2'-Biindoline)-3,3'-dione; (delta(2,2'(3h,3'h))-biindole)-3,3'-dione; (delta(2,2')-biindoline)-3,3'-dione; (delta(sup2,2')-biindoline)-3,3'-dione; (delta2,2'(3H,3'H)-Biindole)-3,3'-dione; (delta2,2'-Biindoline)-3,3'-dione; 11669 Blue. Grades: >98%. CAS No. 482-89-3. Molecular formula: C16H10N2O2. Mole weight: 262.26.
Indirubin
Indirubin is an inhibitor of GSK-3β and cyclin-dependent kinases (CDK1 / cyclin B, CDK2 / cyclin A, CDK2 / cyclin E, CDK4 / cyclin D1, CDK5/p35). Also, Indirubin is a specific Aryl Hydrocarbon receptor (AHR) ligand. Uses: Antibiotics, antineoplastic. Alternative Names: Indirubin; C.I. 73200, Couroupitine B, Indigo red, Indigopurpurin, NSC 105327; NSC-105327; NSC105327; Indigopurpurin; Couroupitine B; [2,3'-Biindolinylidene]-2',3-dione; 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one. Grades: >98%. CAS No. 479-41-4. Molecular formula: C16H10N2O2. Mole weight: 262.268.
Indole-[15N]
Indole-[15N] is the labelled analogue of Indole. Indole is an aromatic heterocyclic organic compound. In very low concentrations, indole is a component of many floral scents and is also used in perfumes. Alternative Names: Indole-15N; CID 12196810. Grades: 98% (CP); 98% atom 15N. CAS No. 40167-58-6. Molecular formula: C8H7[15N]. Mole weight: 118.14.
Indole-3-acetic acid-[2,2-d2]
Indole-3-acetic acid-[2,2-d2] is the labelled analogue of Indole-3-acetic acid. Indole-3-acetic acid, also called as 3-Indoleacetic acid or IAA, predominantly produced in cells of the apex (bud) and very young leaves of a plant, is the most common natural plant growth hormone of the auxin class. Alternative Names: 3-indoleacetic acid-α,α-d2; Deuterated indole-3-acetic acid; Heteroauxin-α,α-d2; IAA-α,α-d2; Indole-3-acetic-2,2-d2 acid. Grades: 98% by CP; 98% atom D. CAS No. 24420-86-8. Molecular formula: C10H7D2NO2. Mole weight: 177.20.
Indole-3-carbinol
Indole-3-carbinol is an inhibitor of cell growth via suppressing incorporation of [3H]thymidine, triggering G1 cell cycle arrest and downregulation of cyclin-dependent kinase 6 (CDK6) expression. It exhibits anticancer activity by inhibition of NF-κB and Akt signaling pathways. Nutritional supplement in health care products. Alternative Names: 3-Indolemethanol; (1H-Indol-3-yl)methanol; Indole-3-methanol; Indol-3-yl-methanol; 3-Hydroxymethylindole; I3C; Indinol. Grades: 98%. CAS No. 700-06-1. Molecular formula: C9H9NO. Mole weight: 147.17.
Indole-3-carboxaldehyde
Indole-3-carboxaldehyde is a tryptophan metabolite from Streptomyces staurosporeus and it is a chemical constituent from Inula wissmanniana. Indole-3-carboxaldehyde and other tryptophan metabolites play an important role in mammalian gut immune homeostasis. Alternative Names: 1H-Indole-3-carboxaldehyde; 1H-Indol-3-yl carboxaldehyde; 1H-Indole-3-aldehyde; 1H-Indole-3-carbaldehyde; 1H-Indole-3-methanal; 3-Formyl-1H-indole; 3-Formylindole; 3-Indolylformaldehyde; Indole-3-aldehyde; Indole-3-carbaldehyde; Indole-3-carboxylaldehyde; Indole-3-formaldehyde; NSC 10118; β-Indolylaldehyde. Grades: ≥95%. CAS No. 487-89-8. Molecular formula: C9H7NO. Mole weight: 145.16.
Indole-3-carboxylic acid
1H-Indole-3-carboxylic acid can be found in the roots of Carpesium abrotanoides. Alternative Names: 1H-indole-3-carboxylic acid. Grades: > 98 %. CAS No. 771-50-6. Molecular formula: C9H7NO2. Mole weight: 161.16.
Indoleacetic Acid-[13C6]
Indoleacetic Acid-[13C6] is an isotopically labelled analogue of Indoleacetic Acid, which is intended for use as an internal standard for the quantification of ledipasvir by GC- or LC-MS. Alternative Names: 1H-Indole-3-acetic-13C6 Acid; (1H-Indol-3-yl)acetic-13C6 Acid; 3-(Carboxymethyl)-1H-indole-13C6; 3-(Carboxymethyl)indole-13C6; 3-Indolylmethylcarboxylic-13C6 Acid; Bioenraiz-13C6; Heteroauxin-13C6; Rhizopin-13C6. Grades: 98% by CP. CAS No. 100849-36-3. Molecular formula: C4[13C]6H9NO2. Mole weight: 181.14.
Indolicidin
Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein, and consists of only six different amino acids. Indolicidin has been shown to be a fairly potent antimicrobial peptide with activity against a variety of microorganisms, fungi, and protozoa. Uses: Anti-infective agents. Alternative Names: cationic antimicrobial peptide; H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2; L-isoleucyl-L-leucyl-L-prolyl-L-tryptophyl-L-lysyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-prolyl-L-tryptophyl-L-arginyl-L-argininamide. Grades: >98%. CAS No. 140896-21-5. Molecular formula: C100H132N26O13. Mole weight: 1906.28.
Indomethacin
A nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Alternative Names: indomethacin;53-86-1;indometacin;Indocin;Indomethacine;Indometacine;Indocid;Reumacide;Indomethazine;Metindol;Artrinovo;Confortid;Idomethine;Indomecol;Indomethacinum;Metartril;Methazine;Artrivia;Dolovin;Imbrilon;Indacin;Indomed;Indomee;Indoptol;Infrocin;Metacen;Sadoreum;Amuno;Inacid;Tannex;Indo-rectolmin;Inteban sp;Artracin;Durametacin;Indoptic;Inflazon;Mikametan;Lausit;Mezolin;Mobilan;Indo-tabline. Grades: 98%. CAS No. 53-86-1. Molecular formula: C18H18O2. Mole weight: 266.3.
(+-)-Indoxacarb
Indoxacarb is used as an oxadiazine pesticide developed by DuPont that acts against lepidopteran larvae. Alternative Names: Methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate. CAS No. 144171-61-9. Molecular formula: C22H17ClF3N3O7. Mole weight: 527.837.
Indoxyl-3a,4,5,6,7,7a-[13C6] sulfate potassium salt
Indoxyl-3a,4,5,6,7,7a-[13C6] sulfate potassium salt is the labelled analogue of 3-Indoxyl Sulfate Potassium Salt. 3-Indoxyl Sulfate Potassium Salt is an uremic toxin that acts as a potent endogenous agonist for the human aryl hydrocarbon receptor (AHR). Alternative Names: Indoxyl-3a,4,5,6,7,7a-13C6 sulfate potassium salt. Grades: ≥ 95% (CP); ≥ 99% atom 13C. Molecular formula: C2[13C]6H6KNO4S. Mole weight: 257.26.
INNO-206
INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Uses: Adcs cytotoxin-linker. Alternative Names: Doxorubicin-hydrazone-caproyl-maleimide; Aldoxorubicin; 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid (2E)-2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide; 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, (2E)-2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]-2-hydroxyethylidene]hydrazide; INNO 206; INNO206. Grades: >98%. CAS No. 1361644-26-9. Molecular formula: C37H42N4O13. Mole weight: 750.75.
Inosine
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. Uses: Coenzymes. Alternative Names: 1,9-Dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 9-β-D-Ribofuranosylhypoxanthine; Hypoxanthine 9-β-D-ribofuranoside; Hypoxanthine Ribonucleoside; Hypoxanthine Riboside; Hypoxanthosine; Ribonosine; Atorel; Oxiamin; Trophicardyl; Selfer; ribo Inosine; HXR; Ino; Inosie; NSC 20262. Grades: ≥98% by HPLC. CAS No. 58-63-9. Molecular formula: C10H12N4O5. Mole weight: 268.23.
Insulin (human)
Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Alternative Names: Recombinant human insulin; Insulin human; H-Phe-Val-Asn-Gln-His-Leu-Cys(1)-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys(2)-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-OH.H-Gly-Ile-Val-Glu-Gln-Cys(3)-Cys(1)-Thr-Ser-Ile-Cys(3)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(2)-Asn-OH; L-phenylalanyl-L-valyl-L-asparagyl-L-glutaminyl-L-histidyl-L-leucyl-L-cysteinyl-glycyl-L-seryl-L-histidyl-L-leucyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-tyrosyl-L-leucyl-L-valyl-L-cysteinyl-glycyl-L-alpha-glutamyl-L-arginyl-glycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-L-threonine (7->7'),(19->20')-bis(disulfide) compound with glycyl-L-isoleucyl-L-valyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-cysteinyl-L-threonyl-L-seryl-L-isoleucyl-L-cysteinyl-L-seryl-L-leucyl-L-tyrosyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-asparagyl-L-tyrosyl-L-cysteinyl-L-asparagine (6'->11')-disulfide. Grades: 95%. CAS No. 11061-68-0. Molecular formula: C257H383N65O77S6. Mole weight: 5807.57.
Inulin-[U-13C]
Inulin-[U-13C] is the labelled analogue of Inulin, which is a group of naturally occurring polysaccharides. Grades: 97% by CP; 97% atom 13C. Molecular formula: ([13C]6H10O5)n.H2O.
Iodinin
Iodinin is an antibiotic produced by the strain of Chromobacterium iodinum etc. It has antibacterial and fungal properties. Alternative Names: 5,6-dihydroxy-10-oxidophenazin-10-ium-1-one; 1,6-Phenazinediol 5,10-dioxide. CAS No. 68-81-5. Molecular formula: C12H8N2O4. Mole weight: 244.20.
Iodoacetamide-[13C2,2-d2]
Iodoacetamide-[13C2,2-d2] is the labelled analogue of 2-Iodoacetamide. 2-Iodoacetamide is an alkylating sulfhydryl reagent. It is also used in ubiquitin studies as an inhibitor of deubiquitinase enzymes (DUBs). Alternative Names: Iodoacetamide-13C2, 2-d2. Grades: 98% atom D; 99% atom 13C. CAS No. 1619234-07-9. Molecular formula: [13C]2H2D2INO. Mole weight: 188.96.
Irganox 1010-[d12]
Irganox 1010-[d12] is the labelled analogue of Irganox 1010 which is a sterically hindered phenolic antioxidant and a heat stabilizer mainly used to enhance the oxidative resistance and protection against the toxicity of solvents. Alternative Names: Tetrakis[methylene-3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]methane-d12; Irganox 1010-d12; d12-Irganox 1010; Anox 20-d12; Anox 20AM-d12; Antiox 10-d12; Antioxidant 1010-d12; Antioxidant 7910-d12. Molecular formula: C73D12H96O12. Mole weight: 1189.63.
Irganox 1010-[d8]
Irganox 1010-[d8] is a labelled analogue of Antioxidant 1010. Pentaerythritol Tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate) is an antioxidant used in food packaging to prevent the spoilage and increase the shelf life of food products. It can be found mainly in food packages made of LDPE, HDPE, PP, PVC and PET. Alternative Names: Pentaerythritol Tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate)-d8; 3,5-Di-tert-butyl-4-hydroxy-hydrocinnamic Acid Neopentanetetrayl Ester-d8; Antioxidant 1010-d8; irganox 1010-d8. Molecular formula: C73H100D8O12. Mole weight: 1185.68.
Irinotecan
Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death. Uses: Anticancer drug. Alternative Names: Irinophore C; Irinotecan lactone; Irinotecan mylan; Onivyde; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; (S)-[1,4'-Bipiperidine]-1'-carboxylic Acid 4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester; Camptosar; Irinotecanum; CPT-11; CPT 11; CPT11; (+)-Irinotecan. Grades: ≥98%. CAS No. 97682-44-5. Molecular formula: C33H38N4O6. Mole weight: 586.68.
Irinotecan EP Impurity E (SN-38)
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. Uses: The treatment of colorectal cancer. Alternative Names: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; 10-Hydroxy-7-ethylcamptothecin; SN 38 Lactone; Irinotecan EP Impurity E; SN-38; USP Irinotecan Related Compound B; Irinotecan Related Compound B; Irinotecan EP Impurity E; NSC-673596. Grades: ≥95%. CAS No. 86639-52-3. Molecular formula: C22H20N2O5. Mole weight: 392.40.
Isoacteoside
Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation, compared with those of aminoguanidine and quercetin as positive controls. Uses: Antioxidant property; anti-inflammatory effect. Alternative Names: 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-a-L-mannopyranosyl)-6-(3-(3,4-dihydroxyphenyl)-2-propenoate)-b-D-glucopyranoside; Isoverbascoside. Grades: >98%. CAS No. 61303-13-7. Molecular formula: C29H36O15. Mole weight: 624.59.
Isoalantolactone
Isoalantolactone has the capacity to inhibit tumor cell growth through induction of apoptosis. Uses: Anti-microbial. Alternative Names: 11(13)-dien-12-oicacid,8-beta-hydroxy-eudesma-4(14gamma-lactone; ISOALANTOACTONE; ISOALANTOLACTONE; ISOHELENIN; (3ar,4as,8ar,9ar)-8a-methyl-3,5-dimethylene-decahydro-naphtho[2,3-b]furan-2-one; methyl-3,5-bis(methylene)-,(3aR,4aS,8aR,9aR)-; Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a-; (3aR)-3aα,4,4aα,5,6,7,8,8a,9,9aα-Decahydro-3,5-bismethylene-8aβ-methylnaphtho[2,3-b]furan-2(3H)-one. Grades: >98%. CAS No. 470-17-7. Molecular formula: C15H20O2. Mole weight: 232.32.
(±)-Isobornyl methyl ether
(±)-Isobornyl methyl ether (CAS# 5331-32-8 ) is a useful research chemical. Alternative Names: (1R,2R,4R)-2-methoxy-1,7,7-trimethylbicyclo[2.2.1]heptane. CAS No. 5331-32-8. Molecular formula: C11H20O. Mole weight: 168.28.
(-)-ISOCARYOPHYLLENE
(-)-ISOCARYOPHYLLENE. Alternative Names: (1r-(1r*,4z,9s*))-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene; (1r-(1r,4z,9s))-4,11,11-trimethyl; (1r-(1r,4z,9s))-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undec-4-ene; (Z)-beta-caryophyllene; ,9s)]-; 4,11,11-trimethyl-8-methylene-,[1R-(1R*,4Z,9S*. CAS No. 118-65-0. Molecular formula: C15H24. Mole weight: 204.35.
Isochlorogenic acid A
3,5-Di-O-caffeoylquinic acid isolated from the flowerbud of Lonicera japonica Thunb. It has hepatoprotective and potent anti-hepatitis B activities. Uses: Antiviral activity; antioxidant activity; antihepatotoxic. Alternative Names: Isochlorogenic acid A;2450-53-5;3,5-Dicaffeoylquinic acid;3,5-Di-O-caffeoylquinic acid;89919-62-0;3,5-DCQA;3,5-Dicaffeoyl-epi-quinic acid;(E,E)-3,5-Di-O-caffeoylquinic acid;Quinic acid 3,5-di-O-caffeate;879305-14-3;(1S,3R,4S,5R)-3,5-Bis(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4-dihydroxycyclohexanecarboxylic acid;(3R,5R)-3,5-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,4-dihydroxycycloh. Grades: 0.98. CAS No. 2450-53-5. Molecular formula: C37H61N5O7S. Mole weight: 720.
Isocupressic acid
Isocupressic acid isolated from the barks of Araucaria cunninghami. It decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of corpus luteum-derived endothelial cells of the uterine tissue results in abortion. Alternative Names: (13E)-15-Hydroxy-8(17),13-labdadiene-19-oic acid; (15-hydroxy-8(17),13E-labdadien-19-oic acid; (1S,4aR,5S,8aR)-5-[(E)-5-hydroxy-3-methylpent-3-enyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid. Grades: 0.965. CAS No. 1909-91-7. Molecular formula: C20H32O3. Mole weight: 320.5.
Isocyclosporin A
A rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. Alternative Names: Ciclosporin Impurity C; O3.1,11-Anhydro[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine]; Isociclosporin A; Cyclosporine EP Impurity C; Iso Cyclosporin A; Ciclosporin EP Impurity C; (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine (11→1)-Lactone; Iso Cyclosporine A; Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy-N-methyl-5-[(E)-1-propenyl]-L-Leu-]]; [2S-(2R*,3S*,4S*,6E)]-N-[3-Hydroxy-4-methyl-2-(methylamino)-1-oxo-6-octenyl]-L-α-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine θ1-lactone. Grades: ≥90% by HPLC. CAS No. 59865-16-6. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Isoengeletin
Isoengeletin is a natural product isolated from the leaves of Engelhardtia roxburghiana Wall. Alternative Names: 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2R,3S)-; (2R,3S)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2R-cis)-; Isoengelitin; (2R,3S)-Engelitin. Grades: 95%. CAS No. 30987-58-7. Molecular formula: C21H22O10. Mole weight: 434.39.
Isoeverninic acid
Isoeverninic acid. Alternative Names: Isoevernic acid. CAS No. 3733-95-7. Molecular formula: C9H10O4. Mole weight: 182.17.
Isoferulic acid
Isoferulic acid isolated from the roots of Cimicifuga foetida L. Alternative Names: (E)-3-(3-Hydroxy-4-methoxyphenyl)propenoic acid;3-Hydroxy-4-methoxy-trans-cinnamic acid;trans-3-(3-Hydroxy-4-methoxyphenyl)acrylic acid;trans-Isoferulic acid. Grades: > 95%. CAS No. 25522-33-2. Molecular formula: C10H10O4. Mole weight: 194.2.
Isoflavone
Isoflavone is a flavonoid with antioxidant properties and antipromotional effects. Isoflavone mainly exists in leguminous plants and are secondary metabolite formed in soybean growth. Because it has a similar structure to estrogen, it is also called phytoestrogen, which can make up for the deficiency of female estrogen secretion after the age of 30, relieve menopause syndrome and improve osteoporosis, so that women can reproduce youthful charm. Isoflavone is effective against aging, with hormone-like effects and no side effects. It can be widely used in anti-aging and wrinkle removal, whitening and light spots, anti-inflammatory and analgesic, hair care, weight loss and other products, and it is compatible with lotion cream formulas, gel formulas and water formulas. Alternative Names: 3-Phenyl-4H-1-benzopyran-4-one; 3-Phenyl-4-chromone; 3-Phenyl-4H-chromen-4-one; 3-Phenylchromone; Isoflavone 20; Isoflavone 80; NSC 135405; Soy Isoflavones; Water-soluble Soy Isoflavones. Grades: 98%. CAS No. 574-12-9. Molecular formula: C15H10O2. Mole weight: 222.24.
Isolariciresinol
Isolariciresinol is a natural lignan found in the herbs of Phyllanthus niruri, it exhibits the activities of antioxidant and anti-inflammatory during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE). Uses: Antioxidant; anti-inflammatory. Alternative Names: (+)-Isolariciresinol; Cyclolariciresinol; (1S)-1,2,3,4-Tetrahydro-7-hydroxy-1α-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2β,3α-naphthalenedimethanol. Grades: 95%. CAS No. 548-29-8. Molecular formula: C20H24O6. Mole weight: 360.40.
(+)-Isolariciresinol 9'-O-glucoside
(+)-Isolariciresinol 9'-O-glucoside is a natural lignin compound found in several plants. Alternative Names: Isolariciresinol-9'-O-beta-D-glucopyranoside. Grades: >97%. CAS No. 63358-12-3. Molecular formula: C26H34O11. Mole weight: 522.54.
Isoliquiritigenin
Isoliquiritigenin, a flavonoid from the root of Glycyrrhiza glabrat, inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μm. It has antioxidant, anti-inflammatory, and anti-tumor activities. Uses: Antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal. Alternative Names: (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; GU 17; 6'-deoxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-; trans-2',4,4'-trihydroxychalcone. Grades: >98%. CAS No. 961-29-5. Molecular formula: C15H12O4. Mole weight: 256.25.
Isolupalbigenin
Isolupalbigenin is extracted from the leaves of Cudrania tricuspidata. It inhibits human glyoxalase I in vitro. It displays promising cytotoxic effects toward HL-60 cells with IC50 value rang from 4.3 ± 0.7 to 18.0 ± 1.7 uM. It has two different antibacterial activities against MRSA including intensifing methicillin sensitivity and inhibiting growth directly. It may be useful for new approaches development against MRSA infection. Alternative Names: 3',8-Di-(dimethylallyl)-genistein; 5,7-Dihydroxy-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-8-(3-methylbut-2-enyl)chromen-4-one. Grades: 97.5%. CAS No. 162616-70-8. Molecular formula: C25H26O5. Mole weight: 406.48.
Isolupanine perchlorate
It is an alkaloid that has been found in L. angustifolius. Alternative Names: Lupanine perchlorate, (-)-; 7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, dodecahydro-, [7S-[7α,7aα,14α,14aα]-, monoperchlorate; α-Isolupanine perchlorate; 11-Isolupanine monoperchlorate; 7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, dodecahydro-, [7S,7aR,14S,14aR]-, perchlorate (1:1). Grades: ≥95%. CAS No. 14691-01-1. Molecular formula: C15H24N2O.ClHO4. Mole weight: 348.82.
Isomartynoside
Isomartynoside is a natural phenylpropanoid found in the roots of Rehmannia glutinosa, it exhibits obvious anti-fatigue activity and may have antihypertensive effect. Uses: Antihypertensive; anti-fatigue. Alternative Names: 2-(4-Methoxy-3-hydroxyphenyl)ethyl-6-O-(4-hydroxy-3-methoxycinnamoyl)-3- O-(α-L-rhamnopyranosyl)-β-D-glucopyranoside. Grades: >95%. CAS No. 94410-22-7. Molecular formula: C31H40O15. Mole weight: 652.7.
(+)-Isomenthol
(+)-Isomenthol is an impurity of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Alternative Names: D-Isomenthol; (1S,2R,5R)-2-Isopropyl-5-methylcyclohexanol; (1S-(1alpha,2beta,5beta))-5-Methyl-(1-isopropyl)cyclohexan-2-ol; Emtricitabine Impurity 7; [1S-(1a,2b,5b)]-5-Methyl-2-(1-methylethyl)cyclohexanol; (1R,3S,4R)-(+)-Menthol; (1S,2R,5R)-(+)-Isomenthol. Grades: 85% by GC. CAS No. 23283-97-8. Molecular formula: C10H20O. Mole weight: 156.26.
(+/-)-Iso Myosmine
(+/-)-Iso Myosmine is a derivative of Nicotine. Alternative Names: (+/-)-Isomyosmine; Pyridine, 3-(3,4-dihydro-2H-pyrrol-2-yl)-; (±)-Iso Myosmine; Myosmine Impurity 3. Grades: 95%. CAS No. 53844-46-5. Molecular formula: C9H10N2. Mole weight: 146.19.
Isopimaric acid is a natural diterpenoid found in the herbs of Daemonorops draco Blume. Isopimaric acid maybe has an antagonistic interaction with reserpine, which may render the antibiotic inactive. Uses: Antagonistic. Alternative Names: 1-phenanthrenecarboxylic acid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-; 7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic acid; 13-Methyl-17-norabieta-7,15-diene-18-oic acid. Grades: >96%. CAS No. 5835-26-7. Molecular formula: C20H30O2. Mole weight: 302.46.
Isopimpinellin
Isopimpinellin is isolated from the roots of Pimpinella saxifraga. It inhibits 7,12-Dimethylbenz(a)anthracene, which is an initiator of skin tumors or breast cancers. Uses: Anti-leishmania effect. Alternative Names: 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one. Grades: 98%. CAS No. 482-27-9. Molecular formula: C13H10O5. Mole weight: 246.2.
(-)-ISOPINOCAMPHEYLAMINE
(-)-ISOPINOCAMPHEYLAMINE. Alternative Names: (-)-ISOPINOCAMPHEYLAMINE; (1R,2R,3R,5S)-(-)-ISOPINOCAMPHEYLAMINE; (1R,2R,3R,5S)-3-PINANAMINE; (1R,2R,3R,5S)-(-)-ISOPINOCAMPHEYLAMINE,95%; (-)-Isopinocampheylamine, (1R,2R,3R,5S)-3-Pinanamine. Grades: 95%. CAS No. 69460-11-3. Molecular formula: C10H19N. Mole weight: 153.26.
Isoprenaline hydrochloride
Isoprenaline is a non-selective beta-adrenergic receptor agonist, used for the treatment of bradycardia and heart block. It would increase cAMP levels and activate protein kinase A and ERK1/2 through its effect on β-adrenoceptor. Uses: The treatment of bradycardia and heart block. Alternative Names: 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride; Isovon; Isuprel; Mistarel; NSC 37745; NSC 89747; Proternol; Saventrine; Suscardia; Vapo-Iso; dl-Isadrine Hydrochloride; dl-Isoprenaline Hydrochloride; dl-Isopropylnoradrenaline Hydrochloride; dl-Isopropylnorepinephrine Hydrochloride; α-(Isopropylaminomethyl)-3,4-dihydroxybenzyl alcohol Hydrochloride; 1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol Hydrochloride. Grades: >98%. CAS No. 51-30-9. Molecular formula: C11H18ClNO3. Mole weight: 247.72.
Isoprocarb-[d3]
Isoprocarb-[d3] is a labelled form of Isoprocarb, a non-systematic carbamate insecticide. Molecular formula: C11H12D3NO2. Mole weight: 196.26.
iso-Propyl-amine-[1,1,1,3,3,3-d6] HCl. Alternative Names: iso-Propyl-1,1,1,3,3,3-d6-amine HCl. Grades: 99% atom D. CAS No. 126794-59-0. Molecular formula: C3H4D6ClN. Mole weight: 101.61.
iso-Propyl amine-[d7] Hydrochloride
Isopropyl-amine-[d7] Hydrochloride is the hydrochloride analogue of Isopropyl-d7-amine, which may act as a potential protease inhibitor but also takes part in numerous organic chemical reactions such as amide synthesis. Alternative Names: 2-Propan-1,1,1,2,3,3,3-d7-amine Hydrochloride; iso-Propyl-d7-amine HCl. Grades: 99 atom % D. CAS No. 106658-10-0. Molecular formula: C3H3D7ClN. Mole weight: 102.61.
Isopropylbenzene-[d12]
Isopropylbenzene-[d12]. Alternative Names: Isopropylbenzene-D12; Cumene-D12. Grades: 98% atom D. CAS No. 97732-82-6. Molecular formula: C9D12. Mole weight: 132.26.
Isopropyl-β-D-thiogalactopyranoside
IPTG is a galactose analog that is used in combination with X-GAL in cloning procedures requiring expression of β-galactosidase activity. Alternative Names: IPTG; Isopropyl-beta-D-thiogalactopyranoside; Isopropyl β-D-thiogalactoside (IPTG); Isopropyl β-D-1-thiogalactopyranoside; Isopropyl 1-thio-b-D-galactopyranoside; Isopropyl 1-Thio-β-D-galactopyranoside; Isopropyl β-D-thiogalactoside; 1-Methylethyl 1-thio-beta-D-galactopyranoside. Grades: ≥98% by HPLC. CAS No. 367-93-1. Molecular formula: C9H18O5S. Mole weight: 238.30.
Isopropyl-[d7]-amine
Isopropyl-[d7]-amine is the labelled analogue of Isopropylamine. Isopropylamine is used as a solvent and to make other chemicals. Alternative Names: 2-Aminopropane-d7; 2-Propan-1,1,1,2,3,3,3-d7-amine. Grades: 98% by CP; 98% atom D. CAS No. 106658-09-7. Molecular formula: C3H2D7N. Mole weight: 66.15.
(-)-ISOPROTERENOL HYDROCHLORIDE
(-)-ISOPROTERENOL HYDROCHLORIDE. Alternative Names: (r)-isoprenalinehydrochloride; (r)-isoproterenolhydrochloride; 1,2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-,hydrochloride,; benzylalcohol,3,4-dihydroxy-alpha-((isopropylamino)methyl)-,hydrochloride,(; l-isoprenalinechloride; l-isoprenalinehydr. CAS No. 5984-95-2. Molecular formula: C11H18ClNO3. Mole weight: 247.72.
Isorhamnetin
Isorhamnetin isolated from the herbs of Typha orientalis Presl. It is efficacious in protecting hepatocytes against oxidative stress by Nrf2 activation and in inducing the expressions of its downstream genes. Uses: Anti-tumor promoter. Alternative Names: 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4h-1-benzopyran-4-one. Grades: 98%. CAS No. 480-19-3. Molecular formula: C16H12O7. Mole weight: 316.3.
Isorhamnetin 3-O-neohesperidoside
Isorhamnetin 3-O-neohesperidoside is a flavonoid glycoside isolated from the leaves of Acacia salicina, exhibiting antioxidant activity. Uses: Removing blood stasis. Alternative Names: Isorhamnetin-3-O-neohesperidoside. Grades: >98%. CAS No. 55033-90-4. Molecular formula: C28H32O16. Mole weight: 624.54.
Isovaleric acid-[d9] is the labelled analogue of Isovaleric acid. Isovaleric acid is found in all eukaryotes from yeast to humans, and has been linked to a number of diseases. Alternative Names: 3-Methylbutyric-d9 acid; Isovaleric-d9 acid; 3-METHYLBUTYRIC-D9 ACID; Isovaleric Acid-d9; SCHEMBL21957851; ACM344298813. Grades: ≥ 97% (CP); ≥ 98% atom D. CAS No. 344298-81-3. Molecular formula: C5HD9O2. Mole weight: 111.19.
Isovitexin
Isovitexin, a food phytochemical contained in dietary rice products, or as a natural plant flavonoid isolated from the seeds of Vitex trifolia L, suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. Isovitexin exhibits anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways. Isovitexin can inhibit xanthine oxidase with an IC50 value of 15.2 microM, and it may protect cells from oxidative stress. Alternative Names: Saponaretin; Homovitexin; (1S)-1,5-anhydro-1-[5,7-dihydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol; 4H-1-Benzopyran-4-one, 6-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 6-β-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Flavone, 6-β-D-glucopyranosyl-4',5,7-trihydroxy-; Homovitexin; 6-C-Glucosylapigenin; 6-C-β-D-Glucopyranosylapigenin; Apigenin 6-C-β-D-glucoside; Apigenin 6-C-β-glucopyranoside; Apigenin-6-C-glucoside; Apigenin-6-C-β-D-glucopyranoside; Avroside; Isoavroside; Isovitexin (C-6 isomer); Saponaretin. Grades: 98%. CAS No. 38953-85-4. Molecular formula: C21H20O10. Mole weight: 432.38.
Isoxanthohumol
Isoxanthohumol is a derivative of xanthohumol in the flavonoids class. It is isolated from the the roots of Sophora flavescens Ait. Isoxanthohumol exhibits antioxidant, anti-inflammatory and antiangiogenic properties. Isoxanthohumol induces apoptosis in mature adipocytes, and inhibits differentiation of preadipocytes. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-, (2S)-; (2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-, (2S)-; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-, (S)-; (-)-Isoxanthohumol; (2S)-7,4'-Dihydroxy-5-methoxy-8-(γ,γ-dimethylallyl)flavanone; Isoxanthohumol (Sophora); (2S)-Isoxanthohumol. Grades: 98%. CAS No. 70872-29-6. Molecular formula: C21H22O5. Mole weight: 354.40.
ISRIB
ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Alternative Names: 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide; 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide; ISRIB compound; trans-ISRIB. CAS No. 1597403-47-8. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34.
ISRIB (mix-Isomer)
ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Alternative Names: Acetamide, N,N'-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)- ISRIB compound. CAS No. 548470-11-7. Molecular formula: C22H24Cl2N2O4. Mole weight: 451.34.
Itaconic Acid-[13C5]
Itaconic Acid-[13C5] is the labelled analogue of Itaconic Acid, a fermentation product of carbohydrates such as glucose using Aspergillus terreus. Itaconic Acid is widely used as a co-monomer in the production of styrene-butadiene-acrylonitrile and acrylate latexes. Alternative Names: 2-Methylenebutanedioic Acid-13C5; 2-Methylenesuccinic Acid-13C5; 2-Propene-1,2-dicarboxylic Acid-13C5; 4-Hydroxy-2-methylene-4-oxobutanoic Acid-13C5; Methylenebutanedioic Acid-13C5; Methylenesuccinic Acid-13C5; NSC 3357-13C5; Propylenedicarboxylic Acid-13C5. Grades: 98% by CP; 99% atom 13C. Molecular formula: 13C5H6O4. Mole weight: 135.06.
Ivabradine hydrochloride
Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Alternative Names: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: >98%. CAS No. 148849-67-6. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05.
Ivdde-L-Lys(Fmoc)-OH
Ivdde-L-Lys(Fmoc)-OH. Alternative Names: (S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)hexanoic acid. Grades: 98%. CAS No. 1446752-60-8. Molecular formula: C34H42N2O6. Mole weight: 574.71.