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Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Alternative Names: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grades: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Alternative Names: Ivermectin; Dihydroavermectin B1a; 22,23-Dihydroavermectin B1a; Ivermectin Component B1a; avermectin H2B1a; 5-O-demethyl-22,23-dihydroavermectin A1a; MK-933; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydroavermectin B(1)a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.; Ivermectin (IVM); IVM; dihydro avermectin Bla; H2B1a; Ivermectin (MK-0933). Grades: >95% by HPLC. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09.
Ivermectin B1a-[d2]
Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Alternative Names: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Grades: ≥94%; ≥95% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11.
Ivermectin B1 aglycone
A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Alternative Names: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grades: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76.
Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Alternative Names: Ivermectin B1b;Avermectin H2B1b;Ivermectin Component B1b;dihydroavermectin B1b;70209-81-3;22,23-dihydroavermectin B1b;0W28CYI3TU;CHEBI:63943;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;UNII-0W28CYI3TU;Stromectol (TN);Soolantra (TN);EINECS 274-384-5;Sklice (TN);H2B1b;CHEMBL552;Ivermectin (JAN/USP/INN);SCHEMBL313003;DTXSID3023182;VARHUCVRRNANBD-PVVXTEPVSA-N;IVERMECTIN COMPONENT B1B [MI];HY-125729;CS-0093431;NS00093438;D00804;Q27132925;5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A;Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. Grades: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C20H38N6O4. Mole weight: 426.6.
Ivermectin-d2
An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: > 95%. Molecular formula: C48H72O14D2. Mole weight: 877.13.
Ivermectin-[d2]
Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2 / Covid-19. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Grades: 98% by CP; 97% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11.
Ivermectin EP Impurity D
Ivermectin EP Impurity D is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: 5-O-demethyl-28-oxo-22,23-dihydroavermectin A1a; 28-oxoH2B1a; 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10.
Ivermectin EP Impurity E
Ivermectin EP Impurity E is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: 5-O,12-didemethyl-12-ethyl-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1a. Molecular formula: C49H76O14. Mole weight: 889.13.
Ivermectin EP Impurity F
Ivermectin EP Impurity F is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: 5-O,12-didemethyl-25-de(1-methylpropyl)-12-ethyl-25-(1-methylethyl)-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1b. Molecular formula: C48H74O14. Mole weight: 875.11.
Ivermectin EP Impurity G
Ivermectin EP Impurity G is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; H2B1a aglycone. Grades: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77.
Ivermectin EP Impurity H
Ivermectin EP Impurity H is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: >95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94.
Ivermectin EP Impurity J
Ivermectin EP Impurity J is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: 2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-3,4,22,23-tetrahydroavermectin A1a; Δ2,3H2B1b. Molecular formula: C47H72O14. Mole weight: 861.08.
Ivermectin EP Impurity K
Ivermectin EP Impurity K is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grades: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13.
Ivermectin monosaccharide
A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Alternative Names: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grades: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92.
Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) is a degradation impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Alternative Names: (2R,2a'Z,4'E,5S,6R,6'S,7'S,8'E,11'R, 15'S, 17a'R,20'R,20a'S)-6-((S)-sec-butyl)-20'-hydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-17'-oxo-2a1',3,4,5,6,6',10',11',14',15',17',17a',20',20a'-tetra decahydro-2'H,7'H-spir[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-2'-carbaldehyde.
Jaceidin
Jaceidin is a natural compound utilized in the biomedical industry. Derived from the plant Bidens pilosa, it exhibits remarkable anti-inflammatory and antimicrobial properties. Jaceidin aids in studying various diseases, including inflammation-related disorders and infectious conditions caused by pathogens. Alternative Names: Jaceidin; 10173-01-0; Jaceidine; Quercetagetin 3,3',6-trimethyl ether; 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxychromen-4-one; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-; 5,7,4'-Trihydroxy-3,6,3'-trimethoxyflavone; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-chromen-4-one; CHEMBL161878; MEGxp0_001561; SCHEMBL13560795; ACon1_000205; DTXSID30144148; CHEBI:175610; LMPK12112999; MFCD20260420; AKOS030553633; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one; NCGC00180783-01; FS-10074; HY-114535; F92980; Q6110552; BRD-K41904382-001-01-5; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one, 9CI. Grades: 98.0%. CAS No. 10173-01-0. Molecular formula: C18H16O8. Mole weight: 360.3.
Jadomycin B
Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Alternative Names: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grades: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6.
(±)-Jasmonic acid
(±)-Jasmonic acid. Alternative Names: (± )-1,2-3-Oxo-2-(cis-2-pentenyl)cyclopentaneacetic acid. CAS No. 77026-92-7. Molecular formula: C12H18O3. Mole weight: 210.27.
(+/-)-Jasmonic acid-9,10-d2. Alternative Names: (+/-)-JASMONIC ACID-9,10-D2; (+/-)-jasmonic acid-9,10-d2, ca. 96atom%d; (+/-)-Jasmonic Acid-9,10-d2 ca. 96atom%D (containing ca. 5% of (+/-)-7-epi-Jasmonic Acid-9,10-d2) (200micro g/ml in Acetonitrile) [Internal standard for qualitative analysis of endogen. CAS No. 183948-71-2. Molecular formula: C12H16D2O3. Mole weight: 212.28.
(±)-Jasmonic acid-[d6]
(±)-Jasmonic acid-[d6] is a labelled form of (±)-Jasmonic acid. Jasmonic acid (JA) is a plant hormone derived from linolenic acid. Alternative Names: {3-Oxo-2-[(2E)-(3,4,4,5,5,5-2H6)-2-penten-1-yl]cyclopentyl}acetic acid. CAS No. 221682-79-7. Molecular formula: C12H12D6O3. Mole weight: 216.31.
Jelleine-I
Jelleine-I is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Pro-Phe-Lys-Leu-Ser-Leu-His-Leu-NH2. Grades: 96.8%. Molecular formula: C47H76N12O9. Mole weight: 952.2.
Jingzhaotoxin III
Jingzhaotoxin III is a selective blocker of NaV1.5 channels with IC50 value of 348 nM. It is selective for NaV1.5 channels and shows no effect on other isoforms. It inhibits the activation of cardiac sodium channels by binding to the NaV1.5 S3-S4 linker of domain II. It has no effect on sodium channels in dorsal root ganglion neurons. Alternative Names: H-Asp-Gly-Glu-Cys(1)-Gly-Gly-Phe-Trp-Trp-Lys-Cys(2)-Gly-Arg-Gly-Lys-Pro-Pro-Cys(3)-Cys(1)-Lys-Gly-Tyr-Ala-Cys(2)-Ser-Lys-Thr-Trp-Gly-Trp-Cys(3)-Ala-Val-Glu-Ala-Pro-OH; L-alpha-aspartyl-glycyl-L-alpha-glutamyl-L-cysteinyl-glycyl-glycyl-L-phenylalanyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-glycyl-L-arginyl-glycyl-L-lysyl-L-prolyl-L-prolyl-L-cysteinyl-L-cysteinyl-L-lysyl-glycyl-L-tyrosyl-L-alanyl-L-cysteinyl-L-seryl-L-lysyl-L-threonyl-L-tryptophyl-glycyl-L-tryptophyl-L-cysteinyl-L-alanyl-L-valyl-L-alpha-glutamyl-L-alanyl-L-proline (4->19),(11->24),(18->31)-tris(disulfide). Grades: >98%. CAS No. 925463-91-8. Molecular formula: C174H241N47O46S6. Mole weight: 3918.44.
JUN68744
JUN68744 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. Alternative Names: JUN-68744; JUN 68744; PSMA-617-linker; PSMA 617-linker; PSMA617-linker; Vipivotide tetraxetan Linker; (((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid. CAS No. 1703768-74-4. Molecular formula: C33H45N5O9. Mole weight: 655.74.
Junicedric acid
Junicedric acid is extracted from the fronds of Dicranopteris linearis or D. ampla. It shows gastroprotective effects. Alternative Names: Mercusic acid; 13S-Dihydroagathic acid; (1S,4aR,5S,8aR)-5-[(3S)-4-carboxy-3-methylbutyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid. CAS No. 41787-69-3. Molecular formula: C20H32O4. Mole weight: 336.47.
Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. It has many functions such as anti-cancer, diuretic, anti-inflammatory, antioxidant, anti-bacterial, and anti-virus. Kaempferol can be used in food additive. Uses: Anti-inflammatory; diuretic; antioxidant; inhibitor of topoisomerase-ii. Alternative Names: Robigenin; Kaempherol; Kempferol; Populnetin; Rhamnolutein. Grades: >98%. CAS No. 520-18-3. Molecular formula: C15H10O6. Mole weight: 286.23.
Kaempferol 3-O-(6''-O-acetyl)glucoside-7-O-rhamnoside is isolated from the roots of Ligusticum jeholense Nakai et Kitag. Alternative Names: Kaempferol 3-(6''-acetylglucoside) 7-rhamnoside. CAS No. 66465-24-5. Molecular formula: C29H32O16. Mole weight: 636.56.
Kaempferol 5,7,4'-trimethyl ether
Kaempferol 5,7,4'-trimethyl ether is an organic natural compound occurring naturally across diverse plant species, showcasing remarkable antioxidative and anticarcinogenic attributes. Alternative Names: 4',5,7-Trimethoxyflavonol; 2-(4-Methoxyphenyl)-3-hydroxy-5,7-dimethoxy-4H-1-benzopyran-4-one. Grades: 0.98. CAS No. 1098-92-6. Molecular formula: C18H16O6. Mole weight: 328.316.
Kanamycin A
Kanamycin is an aminoglycoside antibiotic that has inhibitory effects on gram-positive and negative bacteria and mycoplasma. It can be used for the prevention and treatment of chicken pullorum, colibacillosis, enteritis and other diseases, and has a significant effect on systemic sepsis, respiratory tract infection, peritonitis, etc. caused by drug-resistant bacteria. Uses: Anti-bacterial agents; protein synthesis inhibitors. Alternative Names: Amikacin EP Impurity D; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; 4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6'-diamino-3,6'-dideoxydi-α-D-glucoside; KM; Kanacin; Kanamycin; 6-O-(3-amino-3-deoxy-a-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-2-deoxy-D-streptamine. Grades: 95%. CAS No. 59-01-8. Molecular formula: C18H36N4O11. Mole weight: 484.50.
Kanamycin B
Kanamycin B is an aminoglycoside antibiotic produced by the strain of Str. kanamyceticus. It is used to treat the infection of gram-positive bacteria, gram-negative bacteria and mycobacterium tuberculosis. Uses: Aminoglycoside antibiotic. Alternative Names: Bekanamycin; NK-1006; NK1006; NK 1006; Nebramycin V; Aminodeoxykanamycin; (1R,2S,3S,4R,6S)-4,6-Diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine; 2'-Amino-2'-deoxykanamycin; Beckanamycin; Kanendomycin; KDM; Nebramycin factor 5. Grades: ≥95%. CAS No. 4696-76-8. Molecular formula: C18H37N5O10. Mole weight: 483.51.
Kasugamycin
It is produced by the strain of Str. sugaensis M-388 (ATCC-15714, -15715). Kasugamycin has antibacterial properties against certain bacteria and fungi. Alternative Names: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-; 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-D-chiro-inositol; Kasu B; Kasumin 2L; Kasumin 4WP; Kasumin L; KSM; NSC 100858. Grades: ≥95%. CAS No. 6980-18-3. Molecular formula: C14H25N3O9. Mole weight: 379.36.
Kasugamycin hydrochloride
Kasugamycin hydrochloride is an aminoglycoside antibiotic produced by Streptomyces. It is a broad spectrum antifungal used against yeast and pathogenic fungi such as M. Grisea. Alternative Names: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, hydrochloride (1:1); D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, monohydrochloride; Kasugamycin, monohydrochloride; Kasumin. Grades: ≥73.5%. CAS No. 19408-46-9. Molecular formula: C14H26ClN3O9. Mole weight: 415.82.
Kaurenoic acid is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, and also exhibits cytotoxic and embryotoxic effects. It acts through inhibition of iNOS and COX-2 expression. Uses: Anti-inflammatory. Alternative Names: (-)-Kaur-16-en-18-oic acid;Cunabic acid;Kaurane-16-ene-18-oic acid;ent-Kaur-16(17)-en-19-oic acid;ent-Kaur-16-en-19-oic acid;NSC 339145;Kaur-16-en-18-oic acid,(4a)-. Grades: >98%. CAS No. 6730-83-2. Molecular formula: C20H30O2. Mole weight: 302.46.
Kdo Azide
Kdo Azide is a click chemistry reagent, and it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. Alternative Names: 8-Azido-3,8-dideoxy-D-manno-octulosonic acid. CAS No. 1380099-68-2. Molecular formula: C8H16N4O7. Mole weight: 280.24.
Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. It is used primarily to treat fungal infections. Uses: For the treatment of fungal infections. Alternative Names: Kuric; Nizoral; (2R,4S)-ketoconazole; Fungarest. Grades: >98%. CAS No. 65277-42-1. Molecular formula: C26H28Cl2N4O4. Mole weight: 531.43.
Ketoprofen
Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. Alternative Names: RP-19583; RP 19583; RP19583. Grades: >98%. CAS No. 22071-15-4. Molecular formula: C16H14O3. Mole weight: 254.28.
Kibdelone C
It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Alternative Names: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99.
Kirromycin
Kirromycin is an antibiotic originally isolated from Streptomyces. It was shown to inhibit protein biosynthesis via acting on elongation factor Tu (EF-Tu). Alternative Names: Mocimycin; Delvomycin. Grades: ≥95%. CAS No. 50935-71-2. Molecular formula: C43H60N2O12. Mole weight: 796.94.
Kmeriol
Kmeriol is an extraordinary natural compound innovation, renowned for their awe-inspiring antimicrobial prowess, focusing its force on studying pathogenic bacteria. Alternative Names: 3-(3,4,5-Trimethoxyphenyl)propane-1,2-diol; 3-(3,4,5-Trimethoxyphenyl)-1,2-propanediol. Grades: 98.0%. CAS No. 54306-10-4. Molecular formula: C12H18O5. Mole weight: 242.272.
It is produced from the Aspergillus parasiticus. Kojic Acid has anti-leptospira effect with MIC of 1-10 μg/mL. It is also a tyrosinase inhibitor, which acts as a chelating agent that inhibits the production of melanin and should help chloasma in vitro. Alternative Names: 5-Hydroxy-2-(hydroxymethyl)-4-pyrone; 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-; 2-Hydroxymethyl-5-hydroxy-gamma-pyrone; NSC 1942. Grades: 98%. CAS No. 501-30-4. Molecular formula: C6H6O4. Mole weight: 142.11.
KR-12 is an antibacterial peptide. It has activity against gram-positive bacteria and gram-negative bacteria. Alternative Names: KR-12 (human); Antibacterial Protein LL-37 amide (human) (18-29); H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2. Grades: 95.6%. CAS No. 1218951-51-9. Molecular formula: C71H127N25O15. Mole weight: 1570.9.
Kuwanol C
Kuwanol C is a flavonoid compound found in the root barks of Morus alba L. Alternative Names: 2-(2,4-dihydroxypheny)-5-hydroxy-8methyl-8-(4-methypent-3-en-1-yl)2H,3H,4H,8H-pyrano[3,2-G]chromen-4-one. Grades: >95%. CAS No. 123702-94-3. Molecular formula: C25H26O6. Mole weight: 422.5.
Kynapcin-13
It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 76.80 μmol/L. It has a little inhibitory effect on other serine proteases. Alternative Names: kynapcin 13. Molecular formula: C12H10O7. Mole weight: 266.20.
Kynurenic acid-3,5,6,7,8-[d5]
Kynurenic acid-3,5,6,7,8-[d5] is a labelled product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties. Uses: A labelled product of l-tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties. Alternative Names: Kynurenic acid-3,5,6,7,8-d5; ACM350820132; KYNURENIC-3,5,6,7,8-D5 ACID; Kynurenic Acid-d5; 4-Hydroxy-2-quinolinecarboxylic Acid-d5; 4-Hydroxy-quinaldic Acid-d5; 2-Carboxy-4-hydroxyquinoline-d5; 4-Hydroxyquinaldic Acid-d5; 4-Hydroxyquinaldinic Acid-d5; Quinurenic Acid-d5; NSC 58973-d5. Grades: 97% (CP); 98% atom D. CAS No. 350820-13-2. Molecular formula: C10H2D5NO3. Mole weight: 194.20.
L-2-Aminomethylphenylalanine
L-2-Aminomethylphenylalanine. Alternative Names: L-Phe(2-CH2NH2)-OH. Grades: ≥ 99% by HPLC. CAS No. 158149-99-6. Molecular formula: C10H14N2O2. Mole weight: 194.23.
L-3,5-Difluorophenylalanine
L-3,5-Difluorophenylalanine. Alternative Names: L-Phe(3,5-DiF)-OH; (S)-2-Amino-3-(3,5-difluorophenyl)propionic acid. Grades: ≥ 99% (HPLC). CAS No. 31105-91-6. Molecular formula: C9H9F2NO2. Mole weight: 201.2.
lacticin Q
lacticin Q is an antibacterial peptide isolated from Lactococcus lactis QU 5. It has activity against gram-positive bacteria. Alternative Names: Met-Ala-Gly-Phe-Leu-Lys-Val-Val-Gln-Leu-Leu-Ala-Lys-Tyr-Gly-Ser-Lys-Ala-Val-Gln-Trp-Ala-Trp-Ala-Asn-Lys-Gly-Lys-Ile-Leu-Asp-Trp-Leu-Asn-Ala-Gly-Gln-Ala-Ile-Asp-Trp-Val-Val-Ser-Lys-Ile-Lys-Gln-Ile-Leu-Gly-Ile-Lys.
Lactobionic acid
A disaccharide sugar acid derived from galactose and gluconate. Alternative Names: 4-O-b-D-Galactopyranosyl-D-gluconic acid; 4-(beta-D-Galactosido)-D-gluconic acid. Grades: 98%. CAS No. 96-82-2. Molecular formula: C12H22O12. Mole weight: 358.29.
Lactoferricin
Lactoferricin has Antimicrobial activity. Alternative Names: Met-Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys-Val-Arg-Arg-Ala-Phe. Molecular formula: C134H212N42O27S3. Mole weight: 2939.6.
Lactoferricin B (4-14) (bovine)
Lactoferricin B (4-14) (bovine) is thought to be the main protecting component from bacteria at the mucosal surfaces and in colostrum and milk. The region rich in basic amino acids of bovine lactoferricin is involved in the interaction with the bacterial phospholipid membrane and plays an important role in antimicrobial activity. Alternative Names: Lactotransferrin (20-30) (bovine); H-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-OH; BLFC (4-14); L-arginyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-tryptophyl-L-arginyl-L-methionyl-L-lysyl-L-lysyl-L-leucyl-glycine; Lactoferricin, bovine; Lactoferrin (20-30) (bovine); Lactoferrin (BL-11). Grades: ≥95%. CAS No. 183476-25-7. Molecular formula: C70H113N25O13S. Mole weight: 1544.87.
Lactoferrin (17-41)
Lactoferrin (17-41) is the 17-41 fragment of Lactoferrin that exhibits anti-fungal properties in combination of other anti-fungal agents. Uses:
lactoferrin is a multifunctional glycoprotein that plays a crucial role in various biological processes, including antimicrobial activity, immune modulation, and iron homeostasis. in recent years, research has shown that lactoferrin holds great potential in the field of drug discovery and development due to its diverse range of biological activities and therapeutic properties.
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saliva, te. Alternative Names: Lactoferrin; Lactoferrin, from bovine milk; Lactoferricin B; Lfcin B; H-Phe-Lys-Cys(1)-Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly-Ala-Pro-Ser-Ile-Thr-Cys(1)-Val-Arg-Arg-Ala-Phe-OH. CAS No. 146897-68-9. Molecular formula: C141H224N46O29S3. Mole weight: 3123.78.
Lactose-[UL-13C12] monohydrate
Lactose-[UL-13C12] monohydrate is the labelled analogue of D-Lactose Monohydrate, which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets. Alternative Names: [UL-13C12]lactose monohydrate; 4-O-beta-D-[UL-13C6]galactopyranosyl-D-[UL-13C6]glucose; lactose-13C12 monohydrate. Molecular formula: [13C]12H24O12. Mole weight: 372.22.
L-Alanine
L-alanine is a non-essential amino acid involved in the metabolism of tryptophan and vitamin pyridoxine. Uses:
l-alanine is a non-essential amino acid that plays a vital role in various biological processes in the human body. it is classified as an alpha-amino acid, which means that it contains an amino group and a carboxylic acid group located on the alpha carbon atom. as one of the building blocks of protein, l-alanine is involved in a variety of metabolic pathways and functions that are essential to. Alternative Names: Alanine; (S)-Alanine; H-Ala-OH; Alanine, L-; (2S)-2-Azaniumylpropanoate; (S)-(+)-Alanine; (S)-2-Aminopropanoic acid; L-(+)-Alanine; L-2-Aminopropanoic acid; L-2-Aminopropionic acid; L-α-Alanine; L-α-Aminopropionic acid; Lactamine; NSC 206315; Propanoic acid, 2-amino-, (S)-; α-Alanine; α-Aminopropionic acid. Grades: >98%. CAS No. 56-41-7. Molecular formula: C3H7NO2. Mole weight: 89.09.
L-Alanine-[15N]
L-alanine-[15N] is a labelled L-alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: (S)-2-Aminopropionic acid-15N; L-α-Aminopropionic acid-15N; 15N Labeled L-alanine. Grades: 98% by HPLC; 98% atom 15N. CAS No. 25713-23-9. Molecular formula: C3H7[15N]O2. Mole weight: 90.09.
L-Alanine-[2,3,3,3-d4]
L-Alanine-[2,3,3,3-d4] is a labelled L-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: (2S)-2-Aminopropanoic Acid-d4; (S)-(+)-Alanine-d4; (S)-2-Aminopropanoic Acid-d4. Grades: 95% by HPLC; 98% atom D. CAS No. 18806-29-6. Molecular formula: C3H3D4NO2. Mole weight: 93.12.
L-Alanine-[2-d]
L-Alanine-[2-d] is a labelled L-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: (S)-2-Aminopropanoic Acid-d; H-L-Ala-OH-d; L-Alanine-2-d. Grades: 95% by HPLC; 98% atom D. CAS No. 21386-65-2. Molecular formula: C3H6DNO2. Mole weight: 90.1.
L-Alanine-[3,3,3-d3]
L-Alanine-[3,3,3-d3] is a labelled L-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: (S)-2-Aminopropanoic Acid-d3; H-L-Ala-OH-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 63546-27-0. Molecular formula: C3H4D3NO2. Mole weight: 92.11.
L-Alanine benzyl ester hydrochloride
A benzoxazine derivative used as an additive in the microemulsion formulation for topical applications of acyclovir. A reagent in the preparation of collagenase inhibitors. Alternative Names: L-Ala-OBzl HCl; L-Alanine benzyl ester hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 5557-83-5. Molecular formula: C10H13NO2·HCl. Mole weight: 215.90.
L-Alanine-[d7]
L-Alanine-[d7] is a labelled L-Alanine. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Alternative Names: (S)-2-Aminopropanoic Acid-d7; H-L-Ala-OH-d7. Grades: 95% by HPLC; 98% atom D. CAS No. 74280-71-0. Molecular formula: C3D7NO2. Mole weight: 96.14.
L-Alanine methyl ester hydrochloride
L-Alanine methyl ester is a derivative of L-Alanine. L-Alanine is used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development and is one of the 20 amino acids encoded by the genetic code. Alternative Names: L-Ala-OMe HCl; L-Alaninemethylesterhydrochloride; L-Alanine Methyl Ester Hydrochloride; (S)-Methyl 2-aminopropanoate hydrochloride; H-Ala-OMe HCl; L-2-amino-propanoic acid methyl ester hydrochloride. Grades: ≥ 99% (HPLC). CAS No. 2491-20-5. Molecular formula: C4H9NO2·HCl. Mole weight: 139.60.
(+)-L-Alliin
(+)-L-Alliin is a precursor to Allicin, a cysteine sulfoxide constituent of garlic. Allicin exhibits antibacterial and antioxidant activity. Alternative Names: 3-(Allylsulfinyl)alanine; (S)-L-3-(Allylsulfinyl)-alanine; (S)-3-(2-propenylsulfinyl)-L-Alanine; 3-[(S)-2-Propenylsulfinyl]-L-alanine; Alliin; S-Allyl-L-cysteine-(+)-sulfoxide; L-Cysteine, S-2-propen-1-yl-, S-oxide, [S(S)]-; L-Alanine, 3-(2-propenylsulfinyl)-, (S)-; L-Alanine, 3-[(S)-2-propenylsulfinyl]-; Alanine, 3-(allylsulfinyl)-, (S)-L-. Grades: 98%. CAS No. 556-27-4. Molecular formula: C6H11NO3S. Mole weight: 177.22.