Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| 10-Deacetylbaccatin III | 10-deacetylbaccatin III is a tetracyclic diterpenoid and a secondary alpha-hydroxy ketone. It is functionally related to a baccatin III. Category: Natural extract. Synonyms: 10-Deacetylbaccatin. 10-Deacetylbaccatine III. 10-Deacetyl baccatin III. CAS No. 32981-86-5. Product ID: PIPE-0688. Molecular formula: C29H36O10. Mole weight: 544.6. EINECS: 608-810-1. SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O. Appearance: White to Off-white Solid. |  |
| 1,3-adamantanediacetic acid | 1,3-adamantanediacetic acid. Category: Active pharmaceutical ingredients. CAS No. 17768-28-4. Product ID: API17768284. Molecular formula: C14H20O4. Mole weight: 252.306. | |
| 1,3-adamantanedicarboxylic acid | 1,3-adamantanedicarboxylic acid. Category: Active pharmaceutical ingredients. CAS No. 39269-10-8. Product ID: API39269108. Molecular formula: C12H16O4. Mole weight: 224.25. | |
| 1,3-adamantanedimethanol | 1,3-adamantanedimethanol. Category: Active pharmaceutical ingredients. CAS No. 17071-62-4. Product ID: API17071624. Molecular formula: C12H20O2. Mole weight: 196.286. | |
| 1,3-Dibenzyl-5-fluorouracil | 1,3-Dibenzyl-5-fluorouracil is a chemical inhibitor that suppresses the formation of osteoclasts, functioning by downregulating the signaling pathways of nuclear factor κB ligand receptor activator (Receptor activator of NF-κB ligand, RANKL) and macrophage colony-stimulating factor (M-CSF). This compound is used in the research of metabolic bone diseases. Category: Active pharmaceutical ingredients. CAS No. 75500-02-6. Product ID: API75500026. Molecular formula: C18H15FN2O2. Mole weight: 310.32. | |
| 1,3-dibromoadamantane | 1,3-dibromoadamantane. Category: Active pharmaceutical ingredients. CAS No. 876-53-9. Product ID: API876539. Molecular formula: C10H14Br2. Mole weight: 294.026. | |
| 1,3-dihydroxyadamantane | 1,3-dihydroxyadamantane. Category: Active pharmaceutical ingredients. CAS No. 5001-18-3. Product ID: API5001183. Molecular formula: C10H16O2. Mole weight: 168.233. Appearance: Crystalline. | |
| 1,3-Dimethoxypropan-2-amine | 1,3-Dimethoxypropan-2-amine (also known as 2-amino-1,3-dimethoxypropane) is a symmetrical secondary amine featuring two terminal methoxy groups flanking a central 1,2-diamine-like backbone. The 2-amino-1,3-dimethoxy substitution pattern provides two methoxy groups capable of coordinating to metal ions, while the primary amine provides nucleophilicity and serves as a handle for further functionalization including amidation and sulfonylation. Applications: 1,3-dimethoxypropan-2-amine is used as an intermediate in the synthesis of pharmacologically active compounds, particularly those requiring a flexible ether-amine linker. it is used in the synthesis of nootropic (cognitive-enhancing) agents, local anesthetics, and surface-active agents. the dimethoxypropyl amine scaffold is also found in certain choline analogs and in the synthesis of cross-linking agents for polymer chemistry. Category: Intermediates. Synonyms: 2-Amino-1,3-dimethoxypropane;2-Propanamine, 1,3-dimethoxy-;1,3-Dimethoxy-2-propanamine. CAS No. 78531-29-0. Product ID: INT78531290. Molecular formula: C5H13NO2. Mole weight: 119.16. Appearance: Clear colorless to yellow liquid. | |
| 1,3-dimethyladamantane | 1,3-dimethyladamantane. Category: Active pharmaceutical ingredients. CAS No. 702-79-4. Product ID: API702794. Molecular formula: C12H20. Mole weight: 164.29. | |
| 15-hydroxy Lubiprostone | 15-hydroxy Lubiprostone, synthesized through cyclooxygenase-mediated metabolism of dihomo-γ-linolenic acid (DGLA), functions by inhibiting platelet aggregation (IC50= 40 nM) and enhancing vasodilation. Its analog, 13,14-dihydro-16,16-difluoro PGE1, and the metabolite, 13,14-dihydro PGE1, both retain similar anti-aggregatory properties to the original compound. The inclusion of two electron-withdrawing fluorine atoms in 13,14-dihydro-16,16-difluoro PGE1 is believed to increase molecular stability and potentially extend bioavailability by resisting hydrolytic degradation. Category: Active pharmaceutical ingredients. CAS No. 475992-30-4. Product ID: API475992304. Molecular formula: C20H34F2O5. Mole weight: 392.484. | |
| 1-adamantaneacetic acid | 1-Adamantaneacetic acid was used as an acylating agent in determining pharmacological characteristics of ten new analogues of bradykinin. Category: Active pharmaceutical ingredients. CAS No. 4942-47-6. Product ID: API4942476. Molecular formula: C12H18O2. Mole weight: 194.27. | |
| 1-adamantanecarboxylic acid | 1-adamantanecarboxylic acid. Category: Active pharmaceutical ingredients. CAS No. 828-51-3. Product ID: API828513. Molecular formula: C11H16O2. Mole weight: 180.243. | |
| 1-adamantanemethanol | 1-adamantanemethanol. Category: Active pharmaceutical ingredients. CAS No. 770-71-8. Product ID: API770718. Molecular formula: C11H18O. Mole weight: 166.26. | |
| 1-adamantanol | 1-adamantanol. Category: Active pharmaceutical ingredients. CAS No. 768-95-6. Product ID: API768956. Molecular formula: C10H16O. Mole weight: 152.233. Appearance: Crystalline powder. | |
| 1-bromoadamantane | 1-Bromoadamantane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Category: Active pharmaceutical ingredients. CAS No. 768-90-1. Product ID: API768901. Molecular formula: C10H15Br. Mole weight: 215.13. | |
| 1-chloromethyl-adamantane | 1-chloromethyl-adamantane. Category: Active pharmaceutical ingredients. CAS No. 770-70-7. Product ID: API770707. Molecular formula: C11H17Cl. Mole weight: 184.706. | |
| 1-vinyl adamantane | 1-vinyl adamantane. Category: Active pharmaceutical ingredients. CAS No. 6600-42-6. Product ID: API6600426. Molecular formula: C12H18. Mole weight: 162.271. | |
| 2,3,5,6-Tetrafluoropyridine | 2,3,5,6-Tetrafluoropyridine is a polyfluorinated heterocyclic compound characterized by a pyridine ring where four of the five available carbon-bonded hydrogen atoms have been replaced by fluorine. This electron-deficient aromatic system is a highly versatile building block in the synthesis of specialized pharmaceuticals, agrochemicals, and advanced materials. Its unique chemical reactivity, driven by the strong inductive effect of the fluorine substituents, makes it an essential intermediate for introducing specific fluorinated motifs into complex molecular architectures. Applications: 2,3,5,6-tetrafluoropyridine is extensively utilized in the pharmaceutical industry for the development of fluorinated antiviral agents, kinase inhibitors, and anti-inflammatory drugs. in the agrochemical sector, it serves as a precursor for high-potency herbicides and fungicides that require enhanced environmental stability and systemic activity. it also acts as a valuable reagent in organic synthesis for the preparation of pentafluoropyridine derivatives and other highly functionalized heterocyclic compounds. Category: Intermediates. CAS No. 2875-18-5. Product ID: INT2875185. Molecular formula: C5HF4N. Mole weight: 151.06. EINECS: 622-979-9. InChIKey: HWIPMBCMGVXOKN-UHFFFAOYSA-N. Appearance: Colorless to Light yellow. | |
| 2-adamantanamine | 2-adamantanamine. Category: Active pharmaceutical ingredients. CAS No. 13074-39-0. Product ID: API13074390. Molecular formula: C10H17N. Mole weight: 151.249. | |
| 2-adamantanamine HCl | 2-adamantanamine HCl. Category: Active pharmaceutical ingredients. CAS No. 10523-68-9. Product ID: API10523689. Molecular formula: C10H18ClN. Mole weight: 187.71. | |
| 2-adamantanol | 2-Adamantanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Category: Active pharmaceutical ingredients. CAS No. 700-57-2. Product ID: API700572. Molecular formula: C10H16O. Mole weight: 152.23. Appearance: Powder. | |
| 2-adamantanone | Adamantanone (2-Adamantone) is a bioactive chemical, and can be used for the synthesis of active compound. Category: Active pharmaceutical ingredients. CAS No. 700-58-3. Product ID: API700583. Molecular formula: C10H14O. Mole weight: 150.218. Appearance: Powder or crystalline. | |
| 2-Aminoflubendazole | 2-Aminoflubendazole, a metabolite of benzimidazoles (BZ), belongs to a class of drugs effective against fungi, protozoa, and helminths. Category: Active pharmaceutical ingredients. CAS No. 82050-13-3. Product ID: API82050133. Molecular formula: C14H10FN3O. Mole weight: 255.25. | |
| 2-Azetidinone | 2-Azetidinone (also known as beta-propiolactam) is the simplest four-membered lactam a beta-lactam ring consisting of a nitrogen atom and three carbon atoms in a cyclic amide configuration. As the unsubstituted parent of the beta-lactam antibiotic family (penicillins, cephalosporins, carbapenems), 2-azetidinone serves as the fundamental building block for understanding beta-lactam chemistry and as a precursor for the synthesis of more complex beta-lactam derivatives. Applications: 2-azetidinone is used as a research intermediate in beta-lactam antibiotic synthesis, including the synthesis of monocyclic beta-lactam (aztreonam) analogs, penem derivatives, and carbapenem precursors. the beta-lactam ring is the defining structural feature of one of the most important antibiotic classes in clinical use. modified azetidinone derivatives are also being investigated as serine protease inhibitors and in the development of anti-inflammatory agents. Category: Intermediates. Synonyms: AZETIDIN-2-ONE. CAS No. 930-21-2. Product ID: INT930212. Molecular formula: C3H5NO. Mole weight: 71.08. InChIKey: MNFORVFSTILPAW-UHFFFAOYSA-N. Appearance: Clear colorless liquid. | |
| 2-Fluoroadenine | 2-Fluoroadenine. Category: Intermediates. Synonyms: 2-fluoro-1h-purin-6-amin;2-fluoro-1h-purin-6-amine;2-fluoro-adenin;6-amino-2-fluoro-purin;nsc27364;2-Fluoro-9H-purin-6-amine;6-Amino-2-fluoro-1H-purine;BUTTPARK 25\01-01. CAS No. 700-49-2. Product ID: INT700492. Molecular formula: C5H4FN5. Mole weight: 153.12. EINECS: 624-159-6. Appearance: Solid. | |
| 2-hydroxy Flutamide | 2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer. Category: Active pharmaceutical ingredients. CAS No. 52806-53-8. Product ID: API52806538. Molecular formula: C11H11F3N2O4. Mole weight: 292.21. | |
| 2-Keto Crizotinib | 2-Keto Crizotinib is an active lactam metabolite of crizotinib. Category: Active pharmaceutical ingredients. Synonyms: PF-06260182. CAS No. 1415558-82-5. Product ID: API1415558825. Molecular formula: C21H20Cl2FN5O2. Mole weight: 464.32. | |
| 2-methyl-2-adamantanol | 2-Methyl-2-adamantanol is a chemical used in various research applications. Category: Active pharmaceutical ingredients. CAS No. 702-98-7. Product ID: API702987. Molecular formula: C11H18O. Mole weight: 166.26. Appearance: Crystalline or crystalline powder or chunks. | |
| (3aS,4S,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one | (3aS,4S,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one is a chiral bicyclic lactone containing a fused tetrahydrofuro-furan ring system. This compound is an advanced building block for asymmetric synthesis, providing a rigid, oxygen-rich heterocyclic scaffold with defined stereochemistry and multiple functionalization sites. Applications: Used mainly as a high purity intermediate, (3as,4s,6ar)-4-methoxytetrahydrofuro[3,4-b]furan-2(3h)-one finds application in the synthesis of complex pharmaceutical agents, particularly in the production of protease inhibitors and antiviral drugs. Category: Intermediates. CAS No. 866594-60-7. Product ID: INT866594607. Molecular formula: C7H10O4. Mole weight: 158.15. EINECS: 692-063-1. InChIKey: LQEIOPTZKCKTPQ-VPLCAKHXSA-N. Appearance: White to off-white powder or crystals. | |
| 3-Chloro-2,4,5-trifluorobenzoic acid | 3-Chloro-2,4,5-trifluorobenzoic acid is a highly functionalized aromatic carboxylic acid that serves as a fundamental building block in the pharmaceutical industry. Characterized by a benzene ring substituted with a carboxyl group, a chlorine atom, and three fluorine atoms, this compound exhibits a precise substitution pattern that is critical for the development of advanced fluoroquinolone antibiotics. Its structural rigidity and electronic properties make it a highly desirable intermediate for sophisticated medicinal chemistry applications. Applications: 3-chloro-2,4,5-trifluorobenzoic acid is primarily utilized as a core intermediate in the production of high-potency fluoroquinolone antibiotics such as sitafloxacin. in the pharmaceutical industry, it is employed as a raw material for synthesizing active pharmaceutical ingredients (apis) designed to combat severe multi-drug resistant bacterial infections. it also serves as a specialized reagent in chemical research for exploring the structure-activity relationship (sar) of halogenated benzoic acid derivatives and as a scaffold in the development of other biologically active molecules requiring specific polyfluorinated aryl motifs. Category: Intermediates. CAS No. 101513-77-3. Product ID: INT101513773. Molecular formula: C7H2ClF3O2. Mole weight: 210.54. EINECS: 630-223-4. InChIKey: KBESHLYCSZINAJ-UHFFFAOYSA-N. | |
| (3R,5S)-Fluvastatin sodium | (3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium, a specific isomer of Fluvastatin, functions as a fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 of 8 nM. It is notable for its efficacy in shielding vascular smooth muscle cells from oxidative stress via the Nrf2-dependent antioxidant pathway.'. Category: Active pharmaceutical ingredients. Synonyms: (3R,5S)-XU 62-320. CAS No. 94061-80-0. Product ID: API94061800. Molecular formula: C24H25FNNaO4. Mole weight: 433.45. | |
| (3S,5R)-Fluvastatin D6 sodium | (3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Category: Active pharmaceutical ingredients. Synonyms: (3S,5R)-XU 62-320 D6. CAS No. 2249799-35-5. Product ID: API2249799355. Molecular formula: C24H25FNNaO4. Mole weight: 439.49. | |
| (3S,5R)-Fluvastatin sodium | (3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-. Category: Active pharmaceutical ingredients. CAS No. 94061-81-1. Product ID: API94061811. Molecular formula: C24H26FNNaO4. Mole weight: 434.463. | |
| (3S,5R)-Pitavastatin calcium | (3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 254452-88-5. Product ID: API254452885. Molecular formula: C25H26CaFNO4. Mole weight: 463.562. | |
| (3S,5S)-Atorvastatinent | ent-Atorvastatin is a selective and competitive inhibitor of HMGCR (HMG-CoA reductase). Category: Active pharmaceutical ingredients. CAS No. 501121-34-2. Product ID: API501121342. Molecular formula: C33H35FN2O5. Mole weight: 558.65. | |
| (3S,5S)-Pitavastatin calcium | (3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 254452-92-1. Product ID: API254452921. Molecular formula: C25H26CaFNO4. Mole weight: 463.562. | |
| 4-Nitrophenyl 1,3-Thiazol-5-Ylmethyl Carbonate | 4-Nitrophenyl 1,3-thiazol-5-ylmethyl carbonate (NCT) is one of the most central chiral intermediates in the synthesis of the antiviral drug ritonavir. It forms the "backbone" of the Ritonavir molecular structure and contains a critical hydroxyethylamine isostere. This specific structure mimics the transition state of a protein substrate, which enables the final drug to effectively inhibit viral protease activity. The production of NCT involves complex multi-step chiral synthesis processes, requiring exceptionally high standards for both optical purity (EE value) and chemical purity. Applications: 4-nitrophenyl 1,3-thiazol-5-ylmethyl carbonate (nct) is primarily utilized in the industrial-scale production of high-performance antiretroviral medications, serving as the essential raw material for the preparation of ritonavir. within the synthetic pathway, nct undergoes coupling reactions with specific isocyanates or amino acid derivatives, eventually undergoing condensation to form the active pharmaceutical ingredient (api)-ritonavir. Category: Intermediates. Synonyms: NCT; 4-Nitrophenyl (thiazol-5-ylmethyl) carbonate; 4-Nitrophenyl(thiazol-5-ylmethyl)carbonate; Thiazolylmethyl-4-nitrophenylcarbonate; SY102959; ((5-Thiazolyl)methyl)-(4-nitrophenyl)carbonate. CAS No. 144163-97-3. Product ID: INT144163973. Molecular formula: C11H8N2O5S. Mole weight: 280.26. EINECS: 680-587-3. InChIKey: FTEKBGGQRNJ | |
| 5-Fluorouracil | 5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy. Category: Active pharmaceutical ingredients. CAS No. 51-21-8. Product ID: API51218. Molecular formula: C4H3FN2O2. Mole weight: 130.08. | |
| 5-Hydroxylansoprazole | 5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor used to treat various peptic diseases. Lansoprazole is metabolized through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole. Category: Active pharmaceutical ingredients. CAS No. 131926-98-2. Product ID: API131926982. Molecular formula: C16H14F3N3O3S. Mole weight: 385.36. | |
| 6β-hydroxy Dexamethasone | 6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans. Category: Active pharmaceutical ingredients. CAS No. 55879-47-5. Product ID: API55879475. Molecular formula: C22H29FO6. Mole weight: 408.46. | |
| 6-Hydroxy-1-tetralone | 6-Hydroxy-1-tetralone (also called 6-hydroxy-3,4-dihydronaphthalen-1(2H)-one) is a tetralone (tetrahydronaphthalenone) bearing a phenolic hydroxyl group at the C-6 position of the bicyclic ring system. The cyclohexanone ring fused to the benzene ring creates a 1-tetralone (alpha-tetralone) pharmacophore. The phenolic hydroxyl at C-6 is available for O-alkylation, O-acylation, and oxidative coupling reactions, while the ketone at C-1 is a site for reduction, Wittig, and Grignard reactions. Applications: 6-hydroxy-1-tetralone is used as an intermediate in the synthesis of tamoxifen and related selective estrogen receptor modulators (serms), anthracycline antibiotics (doxorubicin, daunorubicin), and naphthoquinone derivatives. the tetralone scaffold is found in compounds targeting estrogen receptors, protein kinases, and microtubules. it is also used in the synthesis of dyes and organic semiconductors. Category: Intermediates. Synonyms: 6-Hydroxy-3,4-dihydronaphthalen-1(2H)-one. CAS No. 3470-50-6. Product ID: INT3470506. Molecular formula: C10H10O2. Mole weight: 162.19. InChIKey: FNSQPQKPPGALFA-UHFFFAOYSA-N. Appearance: Off-white solid. | |
| 8-hydroxy Efavirenz | 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz. 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM. Category: Active pharmaceutical ingredients. CAS No. 205754-33-2. Product ID: API205754332. Molecular formula: C14H9ClF3NO3. Mole weight: 331.68. | |
| (8R,9S)-Talazoparib | (8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM). Category: Active pharmaceutical ingredients. CAS No. 1207456-00-5. Product ID: API1207456005. Molecular formula: C19H14F2N6O. Mole weight: 380.35. | |
| Abacavir | Antiviral. Category: Active pharmaceutical ingredients. CAS No. 136470-78-5. Product ID: API136470785. Molecular formula: C14H18N6O. Mole weight: 286.34. Appearance: White to Light yellow to Light orange powder to crystal. | |
| Abamectin/Avermectin | Abamectin/Avermectin. Category: Active pharmaceutical ingredients. Synonyms: MLS006011596. CHEMBL80025. SCHEMBL13417423. RRZXIRBKKLTSOM-VDYLCOMISA-N. CAS No. 73989-17-0. Product ID: API73989170. Molecular formula: C48H72O14. Mole weight: 873.1. SMILES: CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C. Standard: Company Standard. | |
| Abemaciclib-d8 | Abemaciclib-d8 is a deuterated compound of Abemaciclib. Abemaciclib has a CAS number of 1231929-97-7. LY2835219 is an effective and specific CDK4/6 inhibitor (IC50: 2/10 nM). Category: Active pharmaceutical ingredients. CAS No. 2088650-53-5. Product ID: API2088650535. Molecular formula: C27H24D8F2N8. Mole weight: 514.64. | |
| Abemaciclib metabolite | Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer. Category: Active pharmaceutical ingredients. CAS No. 2138499-06-4. Product ID: API2138499064. Molecular formula: C27H32F2N8O. Mole weight: 522.59. | |
| Abemaciclib metabolite M18 | Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. Category: Active pharmaceutical ingredients. CAS No. 2704316-81-2. Product ID: API2704316812. Molecular formula: C25H28F2N8O. Mole weight: 494.54. | |
| Abemaciclib methanesulfonate | Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM). Category: Active pharmaceutical ingredients. Synonyms: abemaciclib mesylate, LY2835219, LY2835219 mesylate, LY2835219 (methanesulfonate). CAS No. 1231930-82-7. Product ID: API1231930827. Molecular formula: C27H32F2N8·CH4O3S. Mole weight: 602.7. | |
| Acelarin | Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine. Category: Active pharmaceutical ingredients. CAS No. 840506-29-8. Product ID: API840506298. Molecular formula: C25H27F2N4O8P. Mole weight: 580.47. | |
| Acetamide hydrochloride | antihypertensive. Category: Active pharmaceutical ingredients. CAS No. 1135231-62-7. Product ID: API1135231627. Molecular formula: C20H26ClN3O2. Mole weight: 375.89. | |
| Acetaminophen | Acetaminophen, known as paracetamol outside the United States, stands as one of the most widely used analgesic and antipyretic medications available over the counter. It is chemically distinct from nonsteroidal anti-inflammatory drugs (NSAIDs) and lacks significant anti-inflammatory properties. Applications: Acetaminophen serves as first-line therapy for mild to moderate pain, including headache, dental pain, musculoskeletal discomfort, and postoperative pain, as well as for fever reduction. it is the preferred antipyretic and analgesic during pregnancy and in patients with gastric ulcers or bleeding diatheses. hepatotoxicity represents a dose-limiting danger, with maximum daily doses reduced in patients with hepatic impairment or chronic alcohol use. Category: Active pharmaceutical ingredients. Synonyms: Hydroxyacetanilide; Acetamidophenol; N-Acetyl-p-aminophenol; p-Acetamidophenol. CAS No. 103-90-2. Product ID: API0231577. Molecular formula: C8H9NO2. Mole weight: 151.16. EINECS: 203-157-5. InChIKey: RZVAJINKPMORJF-UHFFFAOYSA-N. Appearance: White crystalline powder. | |
| Acetylcholine Chloride | Acetylcholine chloride is a quaternary ammonium compound that functions as a cholinergic neurotransmitter. For clinical use, it is prepared as an intraocular solution (Miochol-E) for rapid miosis during ophthalmic surgery. The drug is extremely short-acting due to rapid hydrolysis by acetylcholinesterase in tissues, limiting its therapeutic applications to local administration. Applications: Acetylcholine chloride is indicated for the production of rapid, complete miosis during cataract surgery, corneal transplant, and other anterior segment procedures. achieving a constricted pupil protects the corneal endothelium and facilitates lens removal. the drug is injected intracamerally after lens extraction. Category: Active pharmaceutical ingredients. Synonyms: Miochol; Chloroacetylcholine; Ovisot; ACH chloride; 2-Acetoxyethyltrimethylammonium chloride; Choline acetate (ester) chloride; Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride. CAS No. 60-31-1. Product ID: API0231612. Molecular formula: C7H16ClNO2. Mole weight: 181.66. EINECS: 200-468-8. InChIKey: JUGOREOARAHOCO-UHFFFAOYSA-M. Appearance: White crystalline powder. | |
| Acitretin | Acitretin is a second-generation oral retinoid derived from etretinate, used for severe psoriasis and other disorders of keratinization. It is a carboxylic acid metabolite of etretinate with a shorter half-life and no detectable accumulation of etretinate in adipose tissue. Applications: Acitretin is indicated for the treatment of severe, recalcitrant plaque psoriasis, particularly the pustular and erythrodermic variants. it is also used for disorders of cornification such as ichthyosis and darier's disease. Category: Active pharmaceutical ingredients. Synonyms: Etretin; Soriatane; Neotigason; Acitretine; Acitretina. CAS No. 55079-83-9. Product ID: API0231583. Molecular formula: C21H26O3. Mole weight: 326.4. EINECS: 259-474-4. InChIKey: IHUNBGSDBOWDMA-AQFIFDHZSA-N. Appearance: Yellow or greenish-yellow crystalline powder. | |
| Acoramidis | Acoramidis. Category: Active pharmaceutical ingredients. CAS No. 1446711-81-4. Product ID: API1446711814. Molecular formula: C15H17FN2O3. Mole weight: 292.31. | |
| Acteoside | In spite of the fact that acteoside(a biologically active natural product) was first isolated from Verbascum, it is also present in Cistanche and Forsythia. Its stability is not an issue under acid conditions, but the degradation in non - acidic media could be significantly inhibited by adding ascorbic acid. Its potential for drug discovery and development in the future has been considered significant owing to several important pharmacological features-anti - inflammatory, antioxidant, anticancer and neuroprotective, which have been reported over the years. Applications: Acteoside exerts an effect by decreasing tgf-β1 expression to suppress mesangial cell proliferation and delay the progress of glomerulosclerosis. acteoside has been combined with benazepril (a common kidney disease drug) and shown to seemingly improve the therapeutic effect ( acteoside being the key active component in this combination). acteoside has been seen to have a greater effect when compared with benazepril alone for reducing proteinuria. Category: Natural extract. Synonyms: Verbascoside; kusagin. CAS No. 61276-17-3. Product ID: PIPE61276173. Molecular formula: C29H36O15. Mole weight: 624.59. EINECS: 604-604-1. Appearance: White to pale yellow solid. | |
| Acyclovir | Acyclovir is a synthetic purine nucleoside analogue, specifically an oxopurine featuring a (2-hydroxyethoxy)methyl side chain at the N9 position of the guanine ring. Functioning as a potent antiviral agent and antimetabolite, it is widely utilized in the clinical management of various viral infections. Applications: Acyclovir is an antiviral drug that is mainly used to treat infections caused by certain types of viruses. here are the most common uses of acyclovir: genital herpes: acyclovir is commonly used to treat primary and recurrent episodes of genital herpes. cold sores: it can be used to treat herpes labialis (cold sores) caused by hsv type 1. chickenpox: acyclovir can be used to treat chickenp. Category: Active pharmaceutical ingredients. Synonyms: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; Acycloguanosine; Zovirax. Grades: USDMF/CEP/KDMF. CAS No. 59277-89-3. Product ID: API59277893. Molecular formula: C8H11N5O3. Mole weight: 225.21. InChIKey: MKUXAQIIEYXACX-UHFFFAOYSA-N. Standard: USP/CP/EP Facility GMP Product GMP. | |
| Acyclovir Sodium | Acyclovir Sodium is the sodium salt form of acyclovir, a synthetic purine nucleoside analog with potent inhibitory activity against herpes simplex virus types 1 and 2 (HSV-1, HSV-2) and varicella-zoster virus (VZV). As a water-soluble salt, it offers advantages in intravenous formulation and provides reliable antiviral coverage for systemic herpesvirus infections. Applications: Acyclovir sodium is used in the treatment of severe initial and recurrent mucocutaneous herpes simplex virus infections in immunocompromised patients, herpes simplex encephalitis, and varicella-zoster infections including chickenpox and shingles. Category: Active pharmaceutical ingredients. Synonyms: acycloguanosine sodium. CAS No. 69657-51-8. Product ID: API69657518. Molecular formula: C8H10N5NaO3. Mole weight: 247.19. EINECS: 614-996-5. InChIKey: RMLUKZWYIKEASN-UHFFFAOYSA-M. | |
| Adamantane | Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery. Category: Active pharmaceutical ingredients. CAS No. 281-23-2. Product ID: API281232. Molecular formula: C10H16. Mole weight: 136.234. | |
| Adefovir Dipivoxil | Adefovir dipivoxil is an antiviral acyclic nucleoside phosphonate (ANP) analog. Category: Active pharmaceutical ingredients. CAS No. 142340-99-6. Product ID: API142340996. Molecular formula: C20H32N5O8P. Mole weight: 501.47. Appearance: Powder. | |
| Afamelanotide | Afamelanotide. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 75921-69-6. Product ID: API75921696. Molecular formula: C78H111N21O19. Mole weight: 1646.85. EINECS: 211-519-9. Standard: GMP. | |
| Afatinib D6 | Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1313874-96-2. Product ID: API1313874962. Molecular formula: C24H25ClFN5O3. Mole weight: 491.98. | |
| Afatinib oxalate | Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFRwt, 0.4 nM for EGFRL858R, 10 nM for EGFRL858R/T790M, and 14 nM for HER2. Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer. Category: Active pharmaceutical ingredients. CAS No. 1398312-64-5. Product ID: API1398312645. Molecular formula: C28H29ClFN5O11. Mole weight: 666.01. | |
| Afloqualone | Afloqualone (HQ-495) is a quinazolinone family GABAergic drug that acts as an agonist of the β subtype of the GABAa receptor, exhibiting sedative and muscle-relaxant effects. Category: Active pharmaceutical ingredients. CAS No. 56287-74-2. Product ID: API56287742. Molecular formula: C16H14FN3O. Mole weight: 283.3. | |
| AGI-16903 | AGI-16903 is a metabolite of enasidenib -- an isocitrate dehydrogenase-2 inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1643852-84-9. Product ID: API1643852849. Molecular formula: C15H9F6N7. Mole weight: 401.27. | |
| Alalevonadifloxacin | Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa. Alalevonadifloxacin is potentially useful in the treatment of bacterial Gram-positive, Gram-negative and anaerobic infections. Category: Active pharmaceutical ingredients. CAS No. 2892364-59-7. Product ID: API2892364597. Molecular formula: C23H30FN3O8S. Mole weight: 527.56. | |
| Alalevonadifloxacin HCl | Alalevonadifloxacin HCl is a novel l-alanine ester prodrug of levonadifloxacin. Category: Active pharmaceutical ingredients. CAS No. 396132-82-4. Product ID: API396132824. Molecular formula: C22H27ClFN3O5. Mole weight: 467.92. | |
| Alamifovir | Alamifovir is an antiviral drug specific for HBV. It is a purine nucleotide analog prodrug that is active against wild-type and lamivudine-resistant HBV and acts by inhibiting viral DNA initiation and viral DNA packaging, thereby reducing HBV replication. Category: Active pharmaceutical ingredients. CAS No. 193681-12-8. Product ID: API193681128. Molecular formula: C19H20F6N5O5PS. Mole weight: 575.42. | |
| Alatrofloxacin | Alatrofloxacin is a prodrug of trovafloxacin. Category: Active pharmaceutical ingredients. CAS No. 146961-76-4. Product ID: API146961764. Molecular formula: C26H25F3N6O5. Mole weight: 558.51. | |
| Alatrofloxacin Mesylate | Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin. Category: Active pharmaceutical ingredients. CAS No. 157605-25-9. Product ID: API157605259. Molecular formula: C27H29F3N6O8S. Mole weight: 654.62. | |
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