Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Albiglutide | Albiglutide is a sequential dimer of GLP-1 covalently linked to modified human serum albumin (i.e., it is a fusionprotein with modified HSA). Category: Active pharmaceutical ingredients. CAS No. 782500-75-8. Product ID: API782500758. Molecular formula: C148H223N39O46. Mole weight: 3284.58792. InChIKey: OGWAVGNOAMXIIM-VTAHJYCESA-N. |  |
| Albuterol | Albuterol, known as salbutamol outside the United States, is a short-acting beta-2 adrenergic receptor agonist (SABA) that serves as a bronchodilator for reversible obstructive airway diseases. Initially FDA-approved in 1981, it is available in multiple formulations including metered-dose inhalers, nebulizer solutions, tablets, and syrup. As a rescue medication for acute bronchospasm, it remains the most widely prescribed short-acting beta-agonist worldwide. Applications: Albuterol is indicated for treatment or prevention of bronchospasm in patients aged four years and older with reversible obstructive airway disease, and for prevention of exercise-induced bronchospasm. standard dosing for acute symptoms is two inhalations every four to six hours, with onset of bronchodilation within 15 minutes and duration of three to four hours. Category: Bronchiectasis apis. Synonyms: albuterol, Ventoline, Proventil HFA. CAS No. 18559-94-9. Product ID: API0233265. Molecular formula: C13H21NO3. Mole weight: 239.3. EINECS: 242-424-0. InChIKey: NDAUXUAQIAJITI-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| Alectinib | Alectinib is a potent ALK inhibitor. Applications: Anticancer. Category: Anti-tumor apis. CAS No. 1256580-46-7. Product ID: API1256580467. Molecular formula: C30H34N4O2. Mole weight: 482.62. EINECS: 821-541-6. | |
| Alfentanil Hydrochloride | Alfentanil Hydrochloride is the hydrochloride salt of alfentanil, a synthetic opioid analgesic of the 4-anilidopiperidine class. It is a structural analog of fentanyl but with a unique thiazolidinedione substituent, resulting in a considerably shorter onset and duration of action due to its lower lipophilicity and higher plasma protein binding at physiological pH. Applications: Used as a short-acting opioid analgesic for induction and maintenance of anesthesia and for short surgical procedures. alfentanil hydrochloride is a 4-anilidopiperidine opioid with rapid onset and short duration of action due to its low lipophilicity and favorable pharmacokinetic profile. Category: Active pharmaceutical ingredients. Synonyms: Alfentanil HCl. CAS No. 69049-06-5. Product ID: API69049065. Molecular formula: C21H33ClN6O3. Mole weight: 453. InChIKey: AQORHZJDCHLLJN-UHFFFAOYSA-N. Appearance: Solid. | |
| Alflutinib | Alflutinib (Firmonertinib) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition. Category: Active pharmaceutical ingredients. CAS No. 1869057-83-9. Product ID: API1869057839. Molecular formula: C28H31F3N8O2. Mole weight: 568.59. | |
| Alflutinib mesylate | Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M. Category: Active pharmaceutical ingredients. Synonyms: AST2818 mesylate. CAS No. 2130958-55-1. Product ID: API2130958551. Molecular formula: C29H35F3N8O5S. Mole weight: 664.7. | |
| Allicin | Allicin shows antibacterial activity. Category: Natural extract. Synonyms: 2-propene-1-sulfinothioicacid,s-2-propenylester;alliosan;ALLICIN;ALLICIN(SH);ARICINE(P);Dianyctrsnlgide;Allisatin;DIALLYLTHIOSULPHINATE. CAS No. 539-86-6. Product ID: PIPE-0342. Molecular formula: C6H10OS2. Mole weight: 162.27. EINECS: 208-727-7. SMILES: C(S(SCC=C)=O)C=C. InChIKey: JDLKFOPOAOFWQN-UHFFFAOYSA-N. Appearance: Liquid. Standard: In house. | |
| Allopurinol Sodium | Allopurinol Sodium is the sodium salt of allopurinol, a structural isomer of hypoxanthine. It is a potent inhibitor of xanthine oxidase and plays a central role in the pharmacological management of uric acid-related disorders by reducing serum uric acid concentrations. Applications: Indicated for the treatment of gout and hyperuricemia. allopurinol sodium is a xanthine oxidase inhibitor that reduces serum uric acid concentrations by blocking the conversion of hypoxanthine to xanthine and xanthine to uric acid. it is used in chronic gout management, tumor lysis syndrome prevention, and uric acid nephrolithiasis. Category: Active pharmaceutical ingredients. Synonyms: Sodium allopurinol;Allopurinol sodium salt. CAS No. 17795-21-0. Product ID: API17795210. Molecular formula: C5H3N4NaO. Mole weight: 158.09. EINECS: 241-771-5. InChIKey: PTJRZVJXXNYNLN-UHFFFAOYSA-M. Appearance: White to off-white solid. | |
| Almagate | an Antacid Raw material in a specific antacid formulations. Category: Active pharmaceutical ingredients. CAS No. 66827-12-1. Product ID: API66827121. Molecular formula: CH11AlMg3O12. Mole weight: 314.987. Standard: EP/KP. | |
| Almitrine mesylate | Almitrine mesylate (Almitrine dimesylate) inhibits selectively the Ca2+-dependent K+ channel and that in rat chemoreceptor cells,used in the treatment of hypoxemic chronic lung diseases. Category: Active pharmaceutical ingredients. Synonyms: Almitrine dimesylate, Almitrine bismethanesulfonate, Almitrine bismesylate. CAS No. 29608-49-9. Product ID: API29608499. Molecular formula: C28H37F2N7O6S2. Mole weight: 669.76. | |
| Almotriptan Malate | Almotriptan Malate is the malate salt of almotriptan, a second-generation triptan and selective serotonin 5-HT1B/1D receptor agonist. It is designed for cranial selectivity with minimal peripheral vascular effects, offering a favorable drug interaction profile due to its multi-pathway metabolism. Applications: Indicated for the acute treatment of migraine attacks with or without aura in adults. almotriptan malate is a second-generation triptan with superior cranial selectivity, minimal peripheral vascular effects, and a favorable drug interaction profile due to multi-pathway metabolism. Category: Active pharmaceutical ingredients. Synonyms: 1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate;1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine Malate. CAS No. 181183-52-8. Product ID: API181183528. Molecular formula: C21H31N3O7S. Mole weight: 469.6. EINECS: 815-382-1. InChIKey: QHATUKWEVNMHRY-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Alpelisib | Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity, inhibiting PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM). Alpelisib demonstrates antitumor activity and specifically targets PIK3CA mutant tumors. Category: Active pharmaceutical ingredients. CAS No. 1217486-61-7. Product ID: API1217486617. Molecular formula: C19H22F3N5O2S. Mole weight: 441.47. | |
| Alpelisib hydrochloride | Alpelisib hydrochloride (BYL-719 hydrochloride) exhibits anticancer properties. As a potent and selective PI3Kα inhibitor with high oral bioavailability, it has IC50 values of 5 nM for p110α, 250 nM for p110γ, 290 nM for p110δ, and 1200 nM for p110β, indicating its efficacy in targeting enzymes involved in cancer cell proliferation. Category: Active pharmaceutical ingredients. CAS No. 1584128-91-5. Product ID: API1584128915. Molecular formula: C19H23ClF3N5O2S. Mole weight: 477.93. | |
| α-Lipoic Acid | α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. Category: Active pharmaceutical ingredients. CAS No. 1077-28-7. Product ID: API1077287. Molecular formula: C8H14O2S2. Mole weight: 206.326. | |
| Alpha-Tocopherol Acetate | Alpha-tocopherol acetate is the esterified, stabilized form of vitamin E, a fat-soluble antioxidant essential for human health. It is the most biologically active form of vitamin E and is commonly used in oral supplements and topical preparations. The acetate ester protects the active tocopherol from oxidation during storage and is hydrolyzed to free alpha-tocopherol following absorption. Applications: It is indicated for the treatment and prevention of vitamin e deficiency resulting from malabsorption syndromes such as cystic fibrosis, chronic cholestasis, and short bowel syndrome. it is also used as a nutritional supplement in patients with abetalipoproteinemia, where it helps prevent the progressive neurologic deterioration associated with this disorder. topical formulations are employed for their moisturizing and antioxidant properties in cosmetic and dermatologic applications. Category: Vitamin apis. Synonyms: Alfacol; Ecofrol; Contopheron; Tofaxin; Tocopherol acetate; Combinal E; Tokoferol acetate; (2R,4'R,8'R)-alpha-Tocopheryl acetate; 9E8X80D2L0; [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate. CAS No. 7695-91-2. Product ID: API0231523. Molecular formula: C31H52O3. Mole weight: 472.7. EINECS: 231-710-0. InChIKey: ZAKOWWREFLAJOT-CEFNRUSXSA-N. Appearance: Light yellow oily liquid. | |
| Altrenogest | Altrenogest is a progestogen structurally related to veterinary steroid trenbolone. It is a synthetic active progesterone. It can suppress the sow's estrus to achieve the purpose of estrus in the pig herd at the same time, reshape the sow's physiological cycle, and induce the sow to estrus at the same time. Category: Apis for progestogens. Synonyms: Allyltrenbolone. Regumate. Allyl trenbolone. CAS No. 850-52-2. Product ID: API850522. Molecular formula: C21H26O2. Mole weight: 310.4. EINECS: 212-703-1. SMILES: CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(CC=C)O. | |
| aluminium hydroxide | Often used as an antacid active agent, alkaline drug protector or suspending aid; used alone or in combination with magnesium hydroxide; protects the active ingredient by neutralizing the acid while gelling with water. Category: Adsorbents, desiccants and humectants. Synonyms: Dialume. Trihydroxyaluminum. Aluminum trihydroxide. Gibbsite (Al(OH)3). CAS No. 21645-51-2. Product ID: PIE-0168. Molecular formula: AlH6O3. Mole weight: 81.028. SMILES: [OH-].[OH-].[OH-].[Al+3]. Appearance: White, red, or brown mineral. Standard: EP/USP. | |
| Amantadine | 1-Adamantylamine is a building block for an L-piperidinamide catalyst used in an enantioselective Strecker reaction of phosphinoyl imines. Category: Active pharmaceutical ingredients. CAS No. 768-94-5. Product ID: API768945. Molecular formula: C10H17N. Mole weight: 151.25. Appearance: Crystalline. | |
| Ambenonium Chloride | Ambenonium Chloride is a synthetic quaternary ammonium anticholinesterase compound. It is structurally characterized by two benzyl groups and two 2-chloroethyl groups connected through a diamine linker, forming a bis-quaternary ammonium salt that reversibly inhibits acetylcholinesterase. Applications: Indicated for the treatment of myasthenia gravis. ambenonium chloride is a long-acting bis-quaternary anticholinesterase agent that reversibly inhibits acetylcholinesterase at neuromuscular junctions, increasing acetylcholine availability and improving muscle strength in patients with neuromuscular junction disorders. Category: Active pharmaceutical ingredients. Synonyms: (2-chlorobenzyl)-[2-[[2-[2-[(2-chlorobenzyl)-diethyl-ammonio]ethylamino]-2-keto-acetyl]amino]ethyl]-diethyl-ammonium dichloride. CAS No. 115-79-7. Product ID: API115797. Molecular formula: C28H42Cl4N4O2. Mole weight: 608.5. EINECS: 204-107-5. InChIKey: DXUUXWKFVDVHIK-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Ambrisentan | Ambrisentan is an orally active, selective type A endothelin receptor antagonist (ETA) indicated for the treatment of pulmonary arterial hypertension (PAH). It is a high-affinity (Ki=0.011 nM) ETA receptor antagonist with a high selectivity for ETA versus ETB, exceeding 4000-fold. It was initially approved by the FDA in 2007 for use in patients with WHO Class II or III symptoms. Applications: It is indicated for the treatment of pah (who group 1) to improve exercise ability and delay clinical worsening. it can be used as monotherapy or in combination with tadalafil to reduce the risks of disease progression and hospitalization. Category: Active pharmaceutical ingredients. Synonyms: Letairis; Volibris; LU-208075; BSF-208075; HW6NV07QEC; DTXSID4046282; GSK1325760A. CAS No. 177036-94-1. Product ID: API0231572. Molecular formula: C22H22N2O4. Mole weight: 378.4. EINECS: 658-059-9. InChIKey: OUJTZYPIHDYQMC-LJQANCHMSA-N. Appearance: White to off-white crystalline solid. | |
| Amcinonide | Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist. Category: Active pharmaceutical ingredients. CAS No. 51022-69-6. Product ID: API51022696. Molecular formula: C28H35FO7. Mole weight: 502.57. | |
| Amentoflavone | Amentoflavone, is isolated from an Et acetate ext. of the whole plant of Selaginella tamariscina. It has been shown to have antitumor activity, such as mitochondria-mediated apoptotic cell death. Category: Natural extract. Synonyms: AMentotaxus biflavone;DIDEMETHYL-GINKGETIN;I3,II8 BIAPIGENIN;AMENTOFLAVONE;amenthoflavone. CAS No. 1617-53-4. Product ID: PIPE-0143. Molecular formula: C30H18O10. Mole weight: 538.46. EINECS: 000-000-0. InChIKey: YUSWMAULDXZHPY-UHFFFAOYSA-N. Appearance: Yellow. Standard: In house. | |
| Amifostine | Amifostine is an organic thiophosphate prodrug initially developed as a radioprotective agent for military applications. It is a prodrug that is dephosphorylated in vivo to its active metabolite, WR-1065. It functions as a selective cytoprotective agent, administered intravenously to mitigate severe toxicities associated with specific chemotherapeutic agents and radiation therapy. Applications: It is approved to reduce the cumulative renal toxicity associated with repeated cisplatin administration in patients with advanced ovarian cancer. it is also indicated to decrease the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation therapy for head and neck cancer. its use is often limited by significant side effects, including transient hypotension and nausea. Category: Anti-tumor apis. Synonyms: Ethiofos; Gammaphos; Ethyol; Aminopropylaminoethyl thiophosphate; Ethiofos Anhydrous; Amifostine Anhydrous; YM-08310; 2-(3-Aminopropyl)aminoethyl phosphorothioate. CAS No. 20537-88-6. Product ID: API0231502. Molecular formula: C5H15N2O3PS. Mole weight: 214.23. EINECS: 633-786-4. InChIKey: JKOQGQFVAUAYPM-UHFFFAOYSA-N. Appearance: White powder. | |
| Amikacin sulfate | Amikacin disulfate is an aminoglycoside antibiotic that is active against gram-negative bacteria. Category: Active pharmaceutical ingredients. CAS No. 39831-55-5. Product ID: API39831555. Molecular formula: C22H43N5O13 2H2SO4. Mole weight: 781.75. | |
| Aminohippurate Sodium | Aminohippurate sodium (para-aminohippurate or PAH) is an organic anion used to measure effective renal plasma flow (ERPF) and to assess tubular secretion function. It is administered intravenously as a continuous infusion or as a bolus. The drug is also known as PAH and has been a classic renal physiology tool for decades. Applications: Aminohippurate sodium is used to calculate renal plasma flow and to estimate tubular secretory capacity. it is also employed to differentiate between prerenal azotemia and intrinsic renal disease by measuring fractional excretion of pah. Category: Active pharmaceutical ingredients. Synonyms: Sodium p-aminohippurate; p-Aminohippurate sodium; Monosodium p-aminohippurate; Natrium 4-aminohippurat; Sodium para-Aminohippurate. CAS No. 94-16-6. Product ID: API0231645. Molecular formula: C9H9N2NaO3. Mole weight: 216.17. EINECS: 202-309-8. InChIKey: UNZMYCAEMNVPHX-UHFFFAOYSA-M. Appearance: White to off-white crystalline powder. | |
| Aminolevulinic Acid Hydrochloride | Aminolevulinic Acid Hydrochloride is the hydrochloride salt of 5-aminolevulinic acid (5-ALA), a naturally occurring non-proteinogenic amino acid and the first committed precursor in the biosynthesis of tetrapyrrole compounds including heme, chlorophyll, and vitamin B12. It is produced endogenously via condensation of glycine and succinyl-CoA catalyzed by ALA synthase. Applications: Indicated for the treatment of actinic keratosis and superficial basal cell carcinoma through photodynamic therapy (pdt). aminolevulinic acid hydrochloride is a naturally occurring photosensitizer precursor that selectively accumulates in rapidly proliferating cells as protoporphyrin ix, enabling targeted light-activated destruction of abnormal skin cells. Category: Active pharmaceutical ingredients. Synonyms: 5-Aminolevulinic acid hydrochloride. CAS No. 5451-9-2. Product ID: API5451092. Molecular formula: C5H10ClNO3. Mole weight: 167.59. EINECS: 226-679-5. InChIKey: ZLHFONARZHCSET-UHFFFAOYSA-N. Appearance: Off-white solid. | |
| Amiodarone Hydrochloride | Amiodarone hydrochloride is a potent, class III antiarrhythmic agent with complex electrophysiological properties that include activity across all Vaughan-Williams classes. It is available in oral and intravenous formulations and is characterized by an exceptionally long half-life of 40 to 60 days. The drug is highly lipophilic, accumulating extensively in adipose tissue and myocardium, which contributes to its delayed onset and prolonged duration of action. Applications: It is indicated for the treatment of recurrent ventricular fibrillation and hemodynamically unstable ventricular tachycardia, as well as for the maintenance of sinus rhythm in patients with atrial fibrillation or flutter. despite its efficacy, use is often limited by a distinctive adverse effect profile including pulmonary fibrosis, thyroid dysfunction, corneal microdeposits, blue-gray skin discoloration, and hepatotoxicity. regular monitoring of thyroid, liver, and pulmonary function is mandatory during chronic therapy. Category: Antiarrhythmic apis. Synonyms: Amiodarone HCL; Nexterone; Amiodar; Ritmocardyl; Pacerone; Miodaron; Ortacrone; SKF 33134-A; NSC-85442. CAS No. 19774-82-4. Product ID: API0231547. Molecular formula: C25H30ClI2NO3. Mole weight: 681.8. EINECS: 243-293-2. InChIKey: ITPDYQOUSLNIHG-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Amlodipine Besylate | Amlodipine Besylate is a long-acting calcium channel blocker (dihydropyridine class) used as a first-line agent in the treatment of hypertension, stable angina, and Prinzmetal's (vasospastic) angina. Its unique pharmacokinetic profile includes a slow absorption phase and prolonged half-life, providing sustained calcium channel blockade and a gradual, extended reduction in blood pressure over 24 hours with once-daily dosing. Applications: Amlodipine besylate is indicated for the treatment of hypertension (as monotherapy or in combination with other antihypertensives) and for the treatment of stable angina and vasospastic angina. Category: Active pharmaceutical ingredients. Synonyms: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate. CAS No. 111470-99-6. Product ID: API111470996. Molecular formula: C26H31ClN2O8S. Mole weight: 567.1. EINECS: 1312995-182-4. InChIKey: ZPBWCRDSRKPIDG-UHFFFAOYSA-N. Appearance: White powder. | |
| Ammonium Sulfate | Ammonium sulfate is an inorganic sulfate salt obtained by reaction of sulfuric acid with two equivalents of ammonia. A high-melting (decomposes above 280°C) white solid which is very soluble in water (70.6 g/100 g water at 0°C; 103.8 g/100 g water at 100°C), it is widely used as a fertilizer for alkaline soils. It has a role as a fertilizer. It is an ammonium salt and an inorganic sulfate salt. Category: Pharmaceutical excipients. Synonyms: AMMONIUM SULFATE. Ammonium sulphate. Diammonium sulfate. Mascagnite. CAS No. 7783-20-2. Product ID: PIE-0194. Molecular formula: (NH4)2SO4. Mole weight: 132.14. EINECS: 231-984-1. SMILES: [NH4+].[NH4+].[O-]S(=O)(=O)[O-]. Appearance: White or brown orthorhombic Crystals. Standard: NF. | |
| Amoxapine | Amoxapine is a second-generation tricyclic antidepressant of the dibenzoxazepine class, chemically distinct from other tricyclic antidepressants. It is typically used as a second- or third-line treatment option when selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) have failed to control depression. Applications: Amoxapine is indicated for the management of treatment-resistant or persistent depression, particularly in cases accompanied by anxiety, agitation, psychosis, or neurosis. it has been shown to have a more rapid onset of action than either amitriptyline or imipramine. off-label research has also explored its use in reducing chemotherapy-induced diarrhea and managing neuropathic pain. Category: Active pharmaceutical ingredients. Synonyms: Asendin; Demolox; Amoxan; Desmethylloxapin; Amoxapina; Asendis; Amoxapinum; CL 67772. CAS No. 14028-44-5. Product ID: API0231574. Molecular formula: C17H16ClN3O. Mole weight: 313.8. EINECS: 237-867-1. InChIKey: QWGDMFLQWFTERH-UHFFFAOYSA-N. Appearance: White solid. | |
| Amphetamine Adipate | Amphetamine Adipate is the adipate salt of amphetamine, a potent central nervous system stimulant of the amphetamine class. The adipate salt offers improved chemical stability and is used in controlled-release oral formulations. Amphetamine acts as a substrate for monoamine neurotransmitter transporters, increasing the synaptic concentrations of dopamine, norepinephrine, and, to a lesser extent, serotonin in the brain. Applications: Amphetamine adipate is indicated for the treatment of attention deficit hyperactivity disorder (adhd) in children, adolescents, and adults, and for the treatment of narcolepsy. Category: Active pharmaceutical ingredients. CAS No. 64770-51-0. Product ID: API64770510. Molecular formula: C15H23NO4. Mole weight: 281.35. InChIKey: OFCJKOOVFDGTLY-UHFFFAOYSA-N. | |
| Amphetamine Aspartate | Amphetamine aspartate is the aspartate salt form of amphetamine, a synthetic sympathomimetic amine with potent central nervous system stimulating properties. As a Schedule II controlled substance, it appears as a crystalline powder and is formulated into immediate-release and extended-release oral dosage forms for the management of attention-deficit/hyperactivity disorder and narcolepsy. Applications: Amphetamine aspartate is indicated as part of mixed amphetamine salt products for the treatment of attention-deficit/hyperactivity disorder in pediatric and adult populations, where it improves attention span and reduces impulsivity and hyperactivity. it is also approved for the management of narcolepsy to combat excessive daytime sleepiness and sleep attacks. Category: Anesthetic analgesia apis. Synonyms: Amfetamine aspartate; (2S)-2-aminobutanedioic acid; bis(1-phenylpropan-2-amine). CAS No. 25333-81-7. Product ID: API0231654. Molecular formula: C22H33N3O4. Mole weight: 403.5. InChIKey: OJNSNSZTGUACNI-VAGRMJETSA-N. | |
| Amphetamine Sulfate | Amphetamine sulfate is the sulfate salt of amphetamine, a synthetic central nervous system stimulant belonging to the phenethylamine class. Approved by the FDA in 1976, it is classified as a Schedule II controlled substance with a high potential for abuse, misuse, and addiction requiring careful patient selection and monitoring. Applications: Amphetamine sulfate is fda-approved for the treatment of narcolepsy and attention deficit disorder with hyperactivity in children as part of a comprehensive treatment program. it is also indicated as a short-term adjunct in exogenous obesity management for patients refractory to alternative weight reduction therapies. Category: Anesthetic analgesia apis. Synonyms: DL-Amphetamine sulfate, Amphamine sulfate. CAS No. 156-31-0. Product ID: API0233425. Molecular formula: C18H28N2O4S. Mole weight: 368.5. EINECS: 200-457-8. InChIKey: PYHRZPFZZDCOPH-UHFFFAOYSA-N. | |
| Amprenavir | Amprenavir was a protease inhibitor used in the treatment of HIV-1 infection, developed as a second-generation agent with once-daily potential. Applications: Amprenavir was indicated in combination with other antiretrovirals for the treatment of hiv-1 infection in adults and children. Category: Active pharmaceutical ingredients. Synonyms: Agenerase; VX-478; Prozei; 141W94; KVX-478. CAS No. 161814-49-9. Product ID: API0231597. Molecular formula: C25H35N3O6S. Mole weight: 505.6. EINECS: 827-179-5. InChIKey: YMARZQAQMVYCKC-OEMFJLHTSA-N. Appearance: White to beige powder. | |
| Ancitabine Hydrochloride | Ancitabine hydrochloride is an antineoplastic agent. Category: Active pharmaceutical ingredients. CAS No. 10212-25-6. Product ID: API10212256. Molecular formula: C9H11N3O4 HCl. Mole weight: 261.66. Standard: National Drug Standard WS-10001-(HD-1450)-2003. | |
| Andrographolide | Andrographolide is a bicyclic diterpenoid lactone displaying antiviral, antiinflammatory, antiapoptotic, and antihyperglycemic properties. This chemical is an irreversible antagonist of NF-κB and prevents in vitro T cell activation. Andrographolide displays no effect on IκBa degradation but downregulates iNOS and Mac-1 expressions and ROS production. It has been shown to prevent endotoxin shock in mouse models and is reported to activate PI 3K/Akt pathways. Andrographolide is also an inhibitor of ERK. Category: Active pharmaceutical ingredients. CAS No. 5508-58-7. Product ID: API5508587. Molecular formula: C20H30O5. Mole weight: 350.449. Appearance: Powder. | |
| Angiotensin II | Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 4474-91-3. Product ID: API4474913. Molecular formula: C50H71N13O12. Mole weight: 1046.2. EINECS: 2017-001-1. InChIKey: CZGUSIXMZVURDU-JZXHSEFVSA-N. Standard: GMP. | |
| Anileridine Phosphate | Anileridine Phosphate is the phosphate salt of anileridine, a synthetic opioid analgesic of the 4-phenylpiperidine class and a structural analog of pethidine (meperidine). It features a p-aminophenyl group substitution on the piperidine ring nitrogen that distinguishes it from meperidine. Applications: Indicated for the management of moderate to severe pain. anileridine phosphate is a synthetic 4-phenylpiperidine opioid analgesic and a structural analog of meperidine, providing analgesia through mu-opioid receptor agonism with a p-aminophenyl substitution that confers distinct receptor affinity and metabolic profiles. Category: Active pharmaceutical ingredients. Synonyms: 4-Piperidinecarboxylic acid, 1-(2-(4-aminophenyl)ethyl)-4-phenyl-, ethyl ester, phosphate (1:1). CAS No. 1976-75-6. Product ID: API1976756. Molecular formula: C22H31N2O6P. Mole weight: 450.5. InChIKey: FLQCEKVTYABVSH-UHFFFAOYSA-N. | |
| Antazoline Phosphate | Antazoline Phosphate is the phosphate salt of antazoline, a first-generation histamine H1 receptor antagonist belonging to the ethylenediamine class. It is one of the earliest synthetic antihistamines and is structurally characterized by an imidazoline ring system linked to a diphenylmethyl group. Applications: Indicated for the treatment of allergic conjunctivitis and rhinitis. antazoline phosphate is a first-generation ethylenediamine h1 receptor antagonist with additional local anesthetic properties from its imidazoline ring, providing relief from ocular and nasal allergy symptoms including itching, redness, and congestion. Category: Active pharmaceutical ingredients. Synonyms: N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-N-(phenylmethyl)aniline;N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-N-(phenylmethyl)aniline hydrochloride. CAS No. 154-68-7. Product ID: API154687. Molecular formula: C17H22N3O4P. Mole weight: 363.3. EINECS: 205-831-4. InChIKey: DUIGUKRYYAGJAF-UHFFFAOYSA-N. Appearance: White solid. | |
| Antofloxacin | Antofloxacin is a well-tolerated, orally active, and broad-spectrum 8-amino-fluoroquinolone compound that exhibits potent antibacterial properties. It demonstrates superior activity against gyrA mutation-positive Helicobacter pylori strains, particularly in strains with mutations in the Asn87 position, when compared to levofloxacin. Additionally, Antofloxacin acts as a weak but reversible inhibitor of CYP1A2 and is clinically used to treat infections caused by various bacterial species. Category: Active pharmaceutical ingredients. CAS No. 119354-43-7. Product ID: API119354437. Molecular formula: C18H21FN4O4. Mole weight: 376.388. | |
| Antofloxacin Hydrochloride | Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis. Category: Active pharmaceutical ingredients. CAS No. 873888-67-6. Product ID: API873888676. Molecular formula: C18H22ClFN4O4. Mole weight: 412.84. | |
| Apigenin | Apigenin is an antioxidant plant flavanoid which contains anti-inflammatory and anticancer properties. Apigenin may induce apoptosis and may inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase. Apigenin is also known to be a MAP kinase inhibitor and a selective inhibitor of Protein Kinase 2 (CK2). Category: Active pharmaceutical ingredients. CAS No. 520-36-5. Product ID: API520365. Molecular formula: C15H10O5. Mole weight: 270.24. Appearance: Powder. | |
| Apixaban | Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases. Category: Active pharmaceutical ingredients. Synonyms: Eliquis;BMS-562247-01;BMS-562247. Grades: USMF/ASMF/CADMF/China DMF/DMF/WC/KDMF/CDE. CAS No. 503612-47-3. Product ID: API503612473. Molecular formula: C25H25N5O4. Mole weight: 459.5. EINECS: 639-684-6. SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N. Appearance: White to pale-yellow powder. Standard: In-house/CP/USP/EP/JP Facility GMP Product GMP. | |
| Apraclonidine Hydrochloride | Apraclonidine Hydrochloride is a synthetic alpha-2 adrenergic agonist with high selectivity for the alpha-2 receptor subtype, used primarily in ophthalmology for the management of glaucoma and ocular hypertension. Its chemical structure is a clonidine derivative with a para-amino group that reduces its ability to cross the blood-brain barrier, minimizing central nervous system side effects compared to non-selective alpha-2 agonists. Applications: Apraclonidine hydrochloride is indicated for the short-term adjunctive treatment of chronic glaucoma and ocular hypertension in patients who are inadequately controlled by beta-blocker monotherapy. Category: Active pharmaceutical ingredients. Synonyms: 2-(4-amino-2,6-dichlorophenylimino)imidazolidinehydrochloride;2,6-dichloro-n(sup1)-(2-imidazolidinylidene)-1,4-benzenediaminehydrochlorid. CAS No. 73218-79-8. Product ID: API73218798. Molecular formula: C9H11Cl3N4. Mole weight: 281.6. InChIKey: OTQYGBJVDRBCHC-UHFFFAOYSA-N. Appearance: White solid. | |
| Apremilast | Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Category: Active pharmaceutical ingredients. CAS No. 608141-41-9. Product ID: API608141419. Molecular formula: C22H24N2O7S. Mole weight: 460.5. | |
| Aprepitant | Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer. Category: Active pharmaceutical ingredients. Synonyms: MK-869, MK-0869, L-754030, Aprepitant. Grades: USDMF/ASMF/JPMF/CEP/CDE. CAS No. 170729-80-3. Product ID: API170729803. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. Standard: USP/CP/JP; Facility GMP. | |
| Arbutamine Hydrochloride | Arbutamine Hydrochloride is a synthetic catecholamine derivative with non-catechol, nonglycosylated structure designed as a pharmacological stress agent for cardiac diagnostic testing. Its molecular design reduces susceptibility to catechol-O-methyltransferase (COMT)-mediated metabolism, providing a longer duration of action compared to natural catecholamines, while maintaining strong beta-adrenergic agonist activity. Applications: Arbutamine hydrochloride is used as a pharmacological stress agent for diagnostic cardiac testing in patients unable to perform adequate physical exercise. Category: Active pharmaceutical ingredients. CAS No. 125251-66-3. Product ID: API125251663. Molecular formula: C18H24ClNO4. Mole weight: 353.8. InChIKey: ATBUNPBAFFCFKY-FERBBOLQSA-N. | |
| Argatroban | Argatroban is a synthetic direct thrombin inhibitor derived from L-arginine, approved for anticoagulation in patients with heparin-induced thrombocytopenia (HIT). It is administered intravenously, offering rapid onset and predictable dose-response without requiring antithrombin III as a cofactor. Unlike heparin, argatroban does not interact with platelet factor 4, making it safe in HIT. Applications: Argatroban is indicated for prophylaxis or treatment of thrombosis in patients with hit, including those undergoing percutaneous coronary intervention. it is also used off-label in acute ischemic stroke and as an alternative anticoagulant during cardiopulmonary bypass in hit patients. dosing requires adjustment in hepatic impairment but not in renal disease. monitoring is done via aptt, with therapeutic targets typically 1.5-3 times baseline. Category: Active pharmaceutical ingredients. Synonyms: Argatroban anhydrous; Novastan; Acova; Argatrobanum; MD-805; Argipidine. CAS No. 74863-84-6. Product ID: API0231602. Molecular formula: C23H36N6O5S. Mole weight: 508.6. EINECS: 638-764-8. InChIKey: KXNPVXPOPUZYGB-IOVMHBDKSA-N. Appearance: White to off-white crystalline powder. | |
| Arginine Hydrochloride | Arginine Hydrochloride is the hydrochlorides salt of L-arginine, a conditionally essential dibasic amino acid with a guanidino group in its side chain. As a salt form, it provides a stable, free-flowing crystalline powder suitable for pharmaceutical formulation and nutritional supplement production. L-arginine serves as a precursor for nitric oxide (NO) synthesis, creatine, and polyamines, making it critical to multiple physiological pathways. Applications: Arginine hydrochloride is used in nutritional and pharmaceutical formulations as a dietary supplement and as an amino acid source in parenteral nutrition. it is indicated for the treatment of hyperammonemia associated with urea cycle disorders and is used as a nitric oxide precursor in conditions benefiting from enhanced vasodilation. Category: Active pharmaceutical ingredients. Synonyms: L-Arginine/hydrochloric acid;L-2-amino-5-guanidovaleric acid Hydrochloride. CAS No. 15595-35-4. Product ID: API15595354. Molecular formula: C6H15ClN4O2. Mole weight: 210.66. EINECS: 239-674-8. InChIKey: KWTQSFXGGICVPE-WCCKRBBISA-N. Appearance: White powder. | |
| Argipressin | Argipressin binds to the V1-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells. Category: Active pharmaceutical ingredients. CAS No. 113-79-1. Product ID: API113791. Molecular formula: C46H65N15O12S2. Mole weight: 1084.232. | |
| Arotinolol Hydrochloride | Arotinolol Hydrochloride. Category: Active pharmaceutical ingredients. Synonyms: Arotinolol hydrochloride, (S)-. FX47K0HTP6. 2-Thiophenecarboxamide, 5-(2-((3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)thio)-4-thiazolyl)-, monohydrochloride, (S)-. 5-[2-[(2S)-3-(tert-butylamino)-2-hydroxypropyl]sulfanyl-1,3-thiazol-4-yl]thiophene-2-carboxamide;hydrochloride. CAS No. 101540-26-5. Product ID: API101540265. Molecular formula: C15H22ClN3O2S3. Mole weight: 408. SMILES: CC(C)(C)NCC(CSC1=NC(=CS1)C2=CC=C(S2)C(=O)N)O.Cl. | |
| Astemizole | Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. Category: Active pharmaceutical ingredients. CAS No. 68844-77-9. Product ID: API68844779. Molecular formula: C28H31FN4O. Mole weight: 458.57. | |
| Ataluren | Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. Category: Active pharmaceutical ingredients. CAS No. 775304-57-9. Product ID: API775304579. Molecular formula: C15H9FN2O3. Mole weight: 284.24. | |
| Atazanavir | An azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS. Category: Active pharmaceutical ingredients. Synonyms: Atazanavir sulfate. Reyataz. Atazanavir sulphate. Atazanavir (sulfate). CAS No. 229975-97-7. Product ID: API229975977. Molecular formula: C38H54N6O11S. Mole weight: 802.94. EINECS: 620-495-2. SMILES: CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC.OS(=O)(=O)O. Appearance: White to light yellow (Solid). | |
| Atfuzosin Hydrochloride | Alfuzosin HCl is an α1-receptor antagonist used to treat benign prostatic hyperplasia (BPH). Category: Other apis. Synonyms: Alfuzosin-d7HCl;Alfuzosinhydrochlorid;AlfuzosinHydrochloride(150mg);Alfuzosinhydrochloride(Uroxatral);Uroxatral;AlfuzosinhydroChemicalbookcholoride;Uroxatralhydrochloride;N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)-propyl)tetrahydrofuran-2-carboxamid. CAS No. 81403-68-1. Product ID: API81403681. Molecular formula: C19H28ClN5O4. Mole weight: 425.91. EINECS: 620-512-3. Appearance: Solid. Standard: IP. | |
| Atorvastatin | Atorvastatin, an orally active HMG-CoA reductase inhibitor, effectively lowers blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibits the proliferation and invasion of human SV-SMC cells with IC50 values of 0.39 μM and 2.39 μM, respectively. Category: Active pharmaceutical ingredients. CAS No. 134523-00-5. Product ID: API134523005. Molecular formula: C33H35FN2O5. Mole weight: 558.64. | |
| Atorvastatin calcium trihydrate | Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Category: Active pharmaceutical ingredients. Synonyms: CI-981,atorvastatin, calcium salt. CAS No. 344423-98-9. Product ID: API344423989. Molecular formula: C66H74CaF2N4O13. Mole weight: 1209.39. | |
| Atorvastatin-d5 Calcium Salt | Atorvastatin-d5 Calcium Salt is a deuterated compound of Atorvastatin Calcium Salt. Atorvastatin Calcium Salt has a CAS number of 134523-00-5. Category: Active pharmaceutical ingredients. CAS No. 222412-82-0. Product ID: API222412820. Molecular formula: C66H58D10CaF2N4O10. Mole weight: 1165.4. | |
| Atorvastatin ethyl ester | Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity. Category: Active pharmaceutical ingredients. CAS No. 1146977-93-6. Product ID: API1146977936. Molecular formula: C35H39FN2O5. Mole weight: 586.69. | |
| Atorvastatin hemicalcium salt | Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol. Category: Active pharmaceutical ingredients. Synonyms: CI-981, Lipitor, Atorvastatin hemicalcium, Sortis, Atorvastatin Calcium. CAS No. 134523-03-8. Product ID: API134523038. Molecular formula: C33H34FN2O5·1/2Ca. Mole weight: 577.67. | |
| Atorvastatin lactone | Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 125995-03-1. Product ID: API125995031. Molecular formula: C33H33FN2O4. Mole weight: 540.62. | |
| Atorvastatin lysine | Atorvastatin lysine is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor. Category: Active pharmaceutical ingredients. CAS No. 609843-23-4. Product ID: API609843234. Molecular formula: C39H49FN4O7. Mole weight: 704.84. | |
| Atorvastatin magnesium | Atorvastatin magnesium is an HMG-CoA inhibitor. Category: Active pharmaceutical ingredients. CAS No. 874114-41-7. Product ID: API874114417. Molecular formula: C66H68F2MgN4O10. Mole weight: 1139.57. | |
| Atorvastatin methyl ester | Atorvastatin methyl ester is a derivative of Atorvastatin. It inhibits the 9-cis-RA-induced Gal4 reporter activity more strongly than Atorvastatin. Category: Active pharmaceutical ingredients. CAS No. 345891-62-5. Product ID: API345891625. Molecular formula: C34H37FN2O5. Mole weight: 572.67. | |
| Atorvastatin SodiumLipitor | Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocytes. Atorvastatin Sodium treatment inhibits aquaporin 4 to reduce ischaemic brain oedema. Category: Active pharmaceutical ingredients. CAS No. 134523-01-6. Product ID: API134523016. Molecular formula: C33H34FN2NaO5. Mole weight: 580.63. | |
| Atorvastatin strontium | Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia. Category: Active pharmaceutical ingredients. CAS No. 1072903-92-4. Product ID: API1072903924. Molecular formula: C66H68F2N4O10Sr. Mole weight: 1202.9. | |
| Atropine Sulfate | Atropine sulfate is a naturally occurring anticholinergic alkaloid isolated from plants of the Solanaceae family, including Atropa belladonna. It is available as an injectable solution for intravenous, intramuscular, or subcutaneous use, as well as an ophthalmic solution. It is a prescription medication used for a wide range of indications, from emergency cardiac care to ophthalmology. Applications: Atropine sulfate is a critical antidote for organophosphate and nerve agent poisoning, where large, repeated doses are used to counteract muscarinic toxicity. in ophthalmology, it is used to induce mydriasis and cycloplegia for refraction and to treat conditions like amblyopia and uveitis. it is also used off-label to slow gastrointestinal motility in combination products for diarrhea. Category: Anesthetic analgesia apis. Synonyms: Atropt, NSC-755889, NSC26671. CAS No. 55-48-1. Product ID: API0233501. Molecular formula: C34H50N2O11S. Mole weight: 694.8. EINECS: 200-235-0. InChIKey: JPKKQJKQTPNWTR-CHYDPLAESA-N. | |
| Avacincaptad pegol | To treat geographic atrophy secondary to age-related macular degeneration. Category: Active pharmaceutical ingredients. Synonyms: ARC1905. CAS No. 1491144-00-3. Product ID: API1491144003. Molecular formula: C395H492N142O262P39F21((CH2)2O)n. Mole weight: 56 kDa. | |
| Avanafil | Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM. Applications: Ed. Category: Other apis. Synonyms: 4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;Avanafil PDE5 inhibitor. CAS No. 330784-47-9. Product ID: API330784479. Molecular formula: C23H26ClN7O3. Mole weight: 483.95. SMILES: C1(N2CCC[C@H]2CO)=NC=C(C(NCC2=NC=CC=N2)=O)C(NCC2=CC=C(OC)C(Cl)=C2)=N1. InChIKey: WEAJZXNPAWBCOA-INIZCTEOSA-N. Appearance: Solid. | |
| Avapritinib | Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases, targeting KIT D816V (IC50:0.27 nM) and PDGFRA D842V (IC50:0.24 nM), and attenuates the transport functions of ABCB1 and ABCG2. It binds to the active conformation of the kinases and exhibits antitumor activity. Category: Active pharmaceutical ingredients. CAS No. 1703793-34-3. Product ID: API1703793343. Molecular formula: C26H27FN10. Mole weight: 498.56. | |
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