Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Cinacalcet | Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist used in the treatment of cardiovascular disease. Category: Active pharmaceutical ingredients. CAS No. 226256-56-0. Product ID: API226256560. Molecular formula: C22H22F3N. Mole weight: 357.41. |  |
| Cinacalcet hydrochloride | Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and calcimimetic agent that enhances the sensitivity of parathyroid gland calcium-sensing receptors to serum calcium, thereby reducing parathyroid hormone secretion and decreasing serum calcium in the treatment of parathyroid diseases. Category: Active pharmaceutical ingredients. Synonyms: Cinacalcet HCl, AMG-073 hydrochloride, AMG-073 HCl. CAS No. 364782-34-3. Product ID: API364782343. Molecular formula: C22H23ClF3N. Mole weight: 393.87. | |
| Cinacalcet metabolite M4 | Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor. Category: Active pharmaceutical ingredients. CAS No. 104774-87-0. Product ID: API104774870. Molecular formula: C10H12F3N. Mole weight: 203.2. | |
| Cinepazide Maleate | Cinepazide Maleate is a vasodilator. Category: Active pharmaceutical ingredients. CAS No. 26328-04-1. Product ID: API26328041. Molecular formula: C26H35N3O9. Mole weight: 533.571. | |
| Cinolazepam | Cinolazepam is a benzodiazepine derivative drug.It has a powerful sedative effect, so it is mainly used as a hypnotic. Category: Active pharmaceutical ingredients. CAS No. 75696-02-5. Product ID: API75696025. Molecular formula: C18H13ClFN3O2. Mole weight: 357.77. | |
| Ciprofloxacin | Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 85721-33-1. Product ID: API85721331. Molecular formula: C17H18FN3O3. Mole weight: 331.34. | |
| Ciprofloxacin-d8 | Ciprofloxacin-d8 is a deuterated compound of Ciprofloxacin. Ciprofloxacin has a CAS number of 85721-33-1. Ciprofloxacin, a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 1130050-35-9. Product ID: API1130050359. Molecular formula: C17H10D8FN3O3. Mole weight: 339.39. | |
| Ciprofloxacin-d8 Hydrochloride | Ciprofloxacin-d8 Hydrochloride is a deuterated compound of Ciprofloxacin Hydrochloride. Ciprofloxacin Hydrochloride has a CAS number of 93107-08-5. Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline. Category: Active pharmaceutical ingredients. CAS No. 1216659-54-9. Product ID: API1216659549. Molecular formula: C17H11D8ClFN3O3. Mole weight: 375.85. | |
| Ciprofloxacin EP IMpurity AQ-Acid | Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) is an antibiotic and antimicrobial agent. Category: Active pharmaceutical ingredients. CAS No. 86393-33-1. Product ID: API86393331. Molecular formula: C13H9ClFNO3. Mole weight: 281.67. | |
| Ciprofloxacin hydrochloride monohydrate | Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic,is an antibiotic used to treat a number of bacterial infections. Category: Active pharmaceutical ingredients. CAS No. 86393-32-0. Product ID: API86393320. Molecular formula: C17H21ClFN3O4. Mole weight: 385.82. | |
| Ciprofloxacin lactate | Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9. Category: Active pharmaceutical ingredients. CAS No. 97867-33-9. Product ID: API97867339. Molecular formula: C20H24FN3O6. Mole weight: 421.425. | |
| Ciprofloxacin monohydrochloride | Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline. Category: Active pharmaceutical ingredients. CAS No. 93107-08-5. Product ID: API93107085. Molecular formula: C17H18FN3O3·HCl. Mole weight: 367.8. | |
| Cisapride | Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease esophageal reflux. Category: Active pharmaceutical ingredients. CAS No. 81098-60-4. Product ID: API81098604. Molecular formula: C23H29ClFN3O4. Mole weight: 465.95. | |
| Cisapride hydrate | Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic. Category: Active pharmaceutical ingredients. CAS No. 260779-88-2. Product ID: API260779882. Molecular formula: C23H31ClFN3O5. Mole weight: 483.97. | |
| Cisapride tartrate | Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Category: Active pharmaceutical ingredients. CAS No. 189888-25-3. Product ID: API189888253. Molecular formula: C27H35ClFN3O10. Mole weight: 616.04. | |
| cis-(Z)-Flupentixol dihydrochloride | cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist. Category: Active pharmaceutical ingredients. CAS No. 51529-01-2. Product ID: API51529012. Molecular formula: C23H27Cl2F3N2OS. Mole weight: 507.44. | |
| Citalopram-d6 | Citalopram-d6 is a deuterated compound of Citalopram. Citalopram has a CAS number of 59729-33-8. Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enantiomer.Citalopram exhibits antidepressant activity and enhances serotonergic neurotransmission. It can be used to study Alzheimer's disease. Category: Active pharmaceutical ingredients. CAS No. 1190003-26-9. Product ID: API1190003269. Molecular formula: C20H15D6FN2O. Mole weight: 330.43. | |
| Citalopram-d6 Oxalate | Citalopram-d6 Oxalate is a deuterated compound of Citalopram Oxalate. Citalopram Oxalate has a CAS number of 207559-01-1. Category: Active pharmaceutical ingredients. CAS No. 1246819-94-2. Product ID: API1246819942. Molecular formula: C22H17D6FN2O5. Mole weight: 420.46. | |
| Citalopram oxalate | Citalopram oxalate is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition. Category: Active pharmaceutical ingredients. CAS No. 207559-01-1. Product ID: API207559011. Molecular formula: C22H23FN2O5. Mole weight: 414.43. | |
| Clarithromycin | Clarithromycin is an antibacterial prescription medicine to treat certain bacterial infections, such as community-acquired pneumonia, throat infections (pharyngitis), acute sinus infections, and others. Category: Hypoglycemic apis. Synonyms: Biaxin. 6-O-Methylerythromycin. Klaricid. CAS No. 81103-11-9. Product ID: API81103119. Molecular formula: C38H69NO13. Mole weight: 748. EINECS: 617-200-4. SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)O. Appearance: Colorless Acicular Crystalline. | |
| Clebopride Malate | Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Category: Active pharmaceutical ingredients. CAS No. 57645-91-7. Product ID: API57645917. Molecular formula: C24H30ClN3O7. Mole weight: 507.964. Standard: EP/JP. | |
| ClevudineL-FMAU | Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. Category: Active pharmaceutical ingredients. CAS No. 163252-36-6. Product ID: API163252366. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| Clevudine triphosphate | Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate. Category: Active pharmaceutical ingredients. CAS No. 174625-00-4. Product ID: API174625004. Molecular formula: C10H16FN2O14P3. Mole weight: 500.16. | |
| Clindamycin HCl | Clindamycin HCl can reduce the production of leukocidin (PVL), toxic shock Staphylococcal toxin (TSST-1), or alpha-hemolysin (Hla). Category: Active pharmaceutical ingredients. CAS No. 58207-19-5. Product ID: API58207195. Molecular formula: C18H33ClN2O5S · HCl · H2O. Mole weight: 479.46. Standard: USP/EP/BP/CP. | |
| Clindamycin Hydrochloride | Clindamycin Hydrochloride is the hydrochloride salt of clindamycin, a semi-synthetic lincosamide antibiotic derived from lincomycin by replacement of the hydroxyl group at the 7-position with chlorine. This structural modification enhances antibacterial potency and broadens the spectrum of activity compared to the parent compound. Applications: Indicated for the treatment of anaerobic bacterial infections, skin and soft tissue infections, and bone and joint infections. clindamycin hydrochloride is a lincosamide antibiotic with enhanced potency against anaerobes and gram-positive cocci, particularly useful for penicillin-allergic patients and in serious anaerobic infections. Category: Active pharmaceutical ingredients. Synonyms: Clindamycin HCl;monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio. CAS No. 21462-39-5. Product ID: API21462395. Molecular formula: C18H34Cl2N2O5S. Mole weight: 461.4. EINECS: 244-398-6. InChIKey: AUODDLQVRAJAJM-XJQDNNTCSA-N. Appearance: White to off-white solid. | |
| Clindamycin Palmitate HCl | Clindamycin Palmitate HCl can be used to treat various infectious diseases caused by gram-positive bacteria and anaerobic bacteria. Category: Active pharmaceutical ingredients. CAS No. 25507-04-4. Product ID: API25507044. Molecular formula: C34H64Cl2N2O6S. Mole weight: 699.85. Standard: USP/CP. | |
| Clindamycin Phosphate | Clindamycin phosphate is the water-soluble phosphate ester prodrug of clindamycin, a lincosamide antibacterial agent. As a prodrug, it requires in vivo hydrolysis to release the microbiologically active clindamycin base. Applications: Clindamycin phosphate is indicated for serious infections caused by susceptible anaerobic bacteria, streptococci, staphylococci, and pneumococci, including respiratory tract, skin, intra-abdominal, gynecological, and bone and joint infections. it is also widely used topically for acne vulgaris management. Category: Antibacterial apis. Synonyms: Cleocin phosphate, Clindets, Cleocin T. CAS No. 24729-96-2. Product ID: API0232786. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. EINECS: 246-433-0. InChIKey: UFUVLHLTWXBHGZ-MGZQPHGTSA-N. Appearance: White to off-white powder. | |
| Clobetasol | Clobetasol is a topical corticosteroid, glucocorticoid, and antiinflammatory. Category: Active pharmaceutical ingredients. CAS No. 25122-41-2. Product ID: API25122412. Molecular formula: C22H28ClFO4. Mole weight: 410.91. | |
| Clobetasol Propionate-d5 | Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 μg/ml. Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the treatment of inflammatory skin conditions. Category: Active pharmaceutical ingredients. CAS No. 2280940-18-1. Product ID: API2280940181. Molecular formula: C25H27ClD5FO5. Mole weight: 472. | |
| Clobetasone butyrate | Clobetasone butyrate, a synthetic glucocorticoid with topical anti-inflammatory activity, is effective in treating corticosteroid-responsive dermatoses, such as atopic dermatitis and psoriasis, especially within skin tissues. Category: Active pharmaceutical ingredients. CAS No. 25122-57-0. Product ID: API25122570. Molecular formula: C26H32ClFO5. Mole weight: 478.98. | |
| Clocortolone | Clocortolone is a Corticosteroid Hormone Receptor Agonist. It is used in the form of an ester, clocortolone pivalate, and applied as a cream. clocortolone pivalate is used to treat dermatitis and is considered a medium-strength corticosteroid. Category: Active pharmaceutical ingredients. CAS No. 4828-27-7. Product ID: API4828277. Molecular formula: C22H28ClFO4. Mole weight: 410.91. | |
| Clocortolone pivalate | Clocortolone pivalate, a synthetic glucocorticoid corticosteroid and corticosteroid ester, is used to treat seborrheic dermatitis, contact dermatitis, atopic dermatitis, and psoriasis. Category: Active pharmaceutical ingredients. CAS No. 34097-16-0. Product ID: API34097160. Molecular formula: C27H36ClFO5. Mole weight: 495.02. | |
| Clofarabine | Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. Category: Active pharmaceutical ingredients. Synonyms: Clofarex, Evoltra, Clolar. CAS No. 123318-82-1. Product ID: API123318821. Molecular formula: C10H11ClFN5O3. Mole weight: 303.68. | |
| Clopidogrel Besilate | inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. Category: Active pharmaceutical ingredients. CAS No. 744256-69-7. Product ID: API744256697. Molecular formula: C22H22ClNO5S2. Mole weight: 479.997. | |
| Clopimozide | Clopimozide (R-29764) acts as a calcium channel antagonist and inhibits [3H] nilandipine binding.Clopimozide is a novel and orally available long-acting antischizophrenic psychostatic compound. Category: Active pharmaceutical ingredients. CAS No. 53179-12-7. Product ID: API53179127. Molecular formula: C28H28ClF2N3O. Mole weight: 495.99. | |
| Closantel Sodium | Closantel is a salicylaniline anthelmintic, which exhibits a different anthelmintic spectrum and obvious toxicity in mammals. Closamide sodium is widely used in various infections of the above-mentioned parasitic diseases in cattle and sheep. Category: Active pharmaceutical ingredients. Synonyms: Closantel sodium. Closantel (sodium). 0ZBS9YC04P. CAS No. 61438-64-0. Product ID: API61438640. Molecular formula: C22H13Cl2I2N2NaO2. Mole weight: 685.1. EINECS: 262-794-7. SMILES: CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)[O-])Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na+]. Standard: EP/BP. | |
| Clotrimazole | Clotrimazole is a broad-spectrum antifungal agent belonging to the imidazole class, available in numerous over-the-counter and prescription formulations including topical creams, lozenges, and vaginal tablets. It is one of the most widely used antifungal agents due to its favorable safety profile and efficacy against dermatophytes and yeasts. The compound is characterized by its high lipophilicity and minimal systemic absorption following topical administration. Applications: It is indicated for the treatment of superficial fungal infections including tinea pedis, tinea cruris, tinea corporis, and cutaneous candidiasis. the oral troche formulation is used for the prevention and treatment of oropharyngeal candidiasis, particularly in immunocompromised patients. its availability without a prescription for many indications makes it a first-line choice for uncomplicated dermatophyte and yeast infections. Category: Antibacterial apis. Synonyms: Lotrimin; Canesten; Mycelex; Mycosporin; Clotrimazol; Empecid; Mykosporin; Gyne lotrimin; Chlotrimazole; Trimysten; Gyne-Lotrimin; Mycelex G. CAS No. 23593-75-1. Product ID: API23593751. Molecular formula: C22H17ClN2. Mole weight: 344.8. EINECS: 245-764-8. InChIKey: VNFPBHJOKIVQEB-UHFFFAOYSA-N. Appearance: White to faint yellow crystalline powder. | |
| Cobimetinib | Cobimetinib (GDC-0973) is a MEK1 inhibitor (IC50=4.2 nM) with selective and oral activity. Cobimetinib exhibits antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis. Category: Active pharmaceutical ingredients. Synonyms: RG7420, XL518, GDC-0973. CAS No. 934660-93-2. Product ID: API934660932. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
| Cobimetinib hemifumarate | Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1. Category: Active pharmaceutical ingredients. CAS No. 1369665-02-0. Product ID: API1369665020. Molecular formula: C46H46F6I2N6O8. Mole weight: 1178.707. | |
| Cobimetinib racemate | Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated protein kinase, is a key component of the RAS/RAF/MEK/ERK pathway. Category: Active pharmaceutical ingredients. CAS No. 934662-91-6. Product ID: API934662916. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
| Cobimetinib (R-enantiomer) | Cobimetinib R-enantiomer, the less active R-enantiomer of Cobimetinib, is a selective MEK inhibitor. Category: Active pharmaceutical ingredients. Synonyms: Cobimetinib R-enantiomer,GDC-0973 R-enantiomer. CAS No. 934660-94-3. Product ID: API934660943. Molecular formula: C21H21F3IN3O2. Mole weight: 531.318. | |
| Codeine Phosphate | Codeine phosphate is a naturally occurring opium alkaloid classified as a moderate opioid analgesic and antitussive. It is a prodrug that requires metabolic activation to produce most of its analgesic effect. Applications: Codeine is indicated for mild to moderate pain when non-opioid analgesics are insufficient, and as a suppressant for non-productive cough. Category: Active pharmaceutical ingredients. Synonyms: Tricodein; (-)-Codeine Phosphate; DTXSID0024844; Codeini phosphas. CAS No. 52-28-8. Product ID: API0231596. Molecular formula: C18H24NO7P. Mole weight: 397.4. EINECS: 200-137-8. InChIKey: WUXLCJZUUHIXFY-FFHNEAJVSA-N. Appearance: White crystalline powder. | |
| Conivaptan Hydrochloride | Conivaptan hydrochloride is a nonpeptide, dual antagonist of arginine vasopressin receptors approved for intravenous use in hospitalized patients. As the hydrochloride salt formulation, it was initially approved by the FDA in 2005 for raising serum sodium levels in euvolemic and hypervolemic hyponatremia. Applications: Conivaptan hydrochloride is indicated to raise serum sodium in hospitalized patients with euvolemic or hypervolemic hyponatremia associated with conditions such as syndrome of inappropriate antidiuretic hormone secretion, heart failure, or cirrhosis. the drug is contraindicated in hypovolemic hyponatremia, anuria, and with potent cyp3a inhibitors, and its use is limited to short-term inpatient management. Category: Diuretic apis. Synonyms: Vaprisol; YM087; CI-1025. CAS No. 168626-94-6. Product ID: API0232082. Molecular formula: C32H27ClN4O2. Mole weight: 535.04. EINECS: 111-171-7. InChIKey: BTYHAFSDANBVMJ-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Contezolid | Contezolid (MRX-I) is an orally available oxazolidinone antibiotic with bactericidal activity that can be used to study complications of skin tissue infections and tuberculosis caused by drug-resistant Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 1112968-42-9. Product ID: API1112968429. Molecular formula: C18H15F3N4O4. Mole weight: 408.33. | |
| Contezolid acefosamil | Contezolid acefosamil (MRX-4), an orally active prodrug, is metabolized into Contezolid (MRX-I), an oxazolidinone derivative with potent in vitro efficacy against multidrug-resistant Gram-positive bacteria, including MRSA. Category: Active pharmaceutical ingredients. CAS No. 1807497-11-5. Product ID: API1807497115. Molecular formula: C20H18F3N4O8P. Mole weight: 530.353. | |
| Contezolid acefosamil sodium | Contezolid acefosamil sodium (MRX-4) is a novel orally active oxazolidinone antibiotic under investigation for the treatment of complicated skin and soft tissue infections (cSSTI) caused by drug-resistant Gram-positive bacteria. It possesses strong efficacy against these pathogens while significantly minimizing the risks of myelosuppression and monoamine oxidase inhibition (MAOI). Category: Active pharmaceutical ingredients. CAS No. 1807365-35-0. Product ID: API1807365350. Molecular formula: C20H18F3N4NaO8P. Mole weight: 553.343. | |
| Cortisone Acetate | Cortisone acetate (17-hydroxy-11-dehydrocorticosterone), a 21-carbon steroid hormone, is one of the main hormones released by the adrenal gland in response to stress. Category: Active pharmaceutical ingredients. CAS No. 50-04-4. Product ID: API50044. Molecular formula: C23H30O6. Mole weight: 402.481. Appearance: Powder. | |
| Creatine monohydrate | Creatine monohydrate is involved in rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). It can be used as a supplement to study its uptake mechanism and metabolism of action. Category: Mineral salts and nutrients. Synonyms: N-GUANYL-N-METHYLGLYCINE;N-GUANYL-N-METHYLGLYCINE, MONOHYDRATE;N-METHYL-N-GUANYLGLYCINE MONOHYDRATE;N-AMIDINOSARCOSINE;N-AMIDINOSARCOSINE HYDRATE;N-AMIDINOSARCOSINE MONOHYDRATE;Glycine, N-(aminoiminomethyl)-N-methyl-, monohydrate;jisuanyisui. CAS No. 6020-87-7. Product ID: CHE6020877. Molecular formula: C4H11N3O3. Mole weight: 149.15. EINECS: 611-954-8. SMILES: N(C)(C(N)=N)CC(=O)O.O. InChIKey: MEJYXFHCRXAUIL-UHFFFAOYSA-N. Appearance: Crystalline Powder. | |
| Crinecerfont | Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research. Category: Active pharmaceutical ingredients. Synonyms: SSR-125543. CAS No. 752253-39-7. Product ID: API752253397. Molecular formula: C27H28ClFN2OS. Mole weight: 483.04. | |
| Crizotinib | Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors. Category: Active pharmaceutical ingredients. CAS No. 877399-52-5. Product ID: API877399525. Molecular formula: C21H22Cl2FN5O. Mole weight: 450.34. | |
| Crizotinib acetate | Crizotinib, an orally bioavailable agent, belongs to the class of c-met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors with potential antineoplastic activity. Category: Active pharmaceutical ingredients. Synonyms: PF02341066. CAS No. 877399-53-6. Product ID: API877399536. Molecular formula: C23H26Cl2FN5O3. Mole weight: 510.39. | |
| Crizotinib-d5 | Crizotinib-d5 is a deuterated compound of Crizotinib. Crizotinib has a CAS number of 877399-52-5. Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor. Category: Active pharmaceutical ingredients. CAS No. 1395950-84-1. Product ID: API1395950841. Molecular formula: C21H17D5Cl2FN5O. Mole weight: 455.37. | |
| Crizotinib hydrochloride | Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met, with IC50 values of 20 nM and 8 nM, respectively. Category: Active pharmaceutical ingredients. Synonyms: PF-02341066 hydrochloride. CAS No. 1415560-69-8. Product ID: API1415560698. Molecular formula: C21H23Cl3FN5O. Mole weight: 486.8. | |
| Cromolyn Sodium | Cromolyn sodium is a mast cell stabilizer derived from khellin, a natural extract from the eastern Mediterranean herb Ammi visnaga. First introduced as an inhaled treatment for asthma in 1969, it is available in multiple formulations including inhalation solution, nasal spray, ophthalmic solution, and oral concentrate. It is a white to off-white powder freely soluble in water, formulated as a sterile solution for various routes of administration. Applications: Cromolyn sodium is fda-approved for prophylaxis of mild to moderate bronchial asthma, allergic rhinitis, systemic mastocytosis, and treatment of vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. it is not effective for acute attacks and must be used prophylactically at regular intervals. Category: Antiasthmatic apis. Synonyms: Sodium cromoglycate, Disodium cromoglycate. CAS No. 15826-37-6. Product ID: API0233278. Molecular formula: C23H14Na2O11. Mole weight: 512.3. EINECS: 239-926-7. InChIKey: VLARUOGDXDTHEH-UHFFFAOYSA-L. | |
| Croscarmellose Sodium | Croscarmellose sodium is a crosslinked polymer of carboxymethyl_x0002_cellulose sodium. Category: Disintegrant excipients. Synonyms: Acdisol SD711 NF; Sodium Carboxymethylcellulose, Sodium CMC; Croscarmellose Sodium; Udisol SD711 NF. Grades: DMF. CAS No. 74811-65-7. Product ID: PIE-0029. Appearance: Odorless, white or grayishwhite powder. Standard: USP/EP/BP/ChP/JP/NF. | |
| Cyclacillin | Cyclacillin is a semisynthetic aminopenicillin antibiotic with a broader spectrum than penicillin but less potent than ampicillin. The drug is unique among penicillins for its rapid oral absorption and high urinary recovery. Applications: Cyclacillin was indicated for respiratory tract infections (otitis media, pharyngitis, sinusitis), urinary tract infections, and skin/soft tissue infections caused by susceptible organisms. Category: Active pharmaceutical ingredients. Synonyms: Aminocyclohexylpenicillin; Bastcillin; Cyclapen; Ultracillin. CAS No. 3485-14-1. Product ID: API0231640. Molecular formula: C15H23N3O4S. Mole weight: 341.4. EINECS: 222-470-8. InChIKey: HGBLNBBNRORJKI-WCABBAIRSA-N. Appearance: White to off-white solid. | |
| Cyclen | Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocyclic tetraamine featuring a 12-membered ring with four nitrogen atoms separated by two-carbon ethylene linkers. As a cyclam analog, cyclen is a well-known metal-chelating ligand that forms extremely stable complexes with transition metal and lanthanide ions. Its cavity size is optimal for binding to smaller metal ions (Cu2+, Zn2+, Ni2+) compared to the larger cyclam ring. Applications: Cyclen is used as a key intermediate in the synthesis of bifunctional chelators for nuclear medicine (radiopharmaceuticals), mri contrast agents (gd-dota is based on cyclen), and luminescent lanthanide complexes. the 1,4,7,10-tetraazacyclododecane scaffold is also used in the synthesis of cyclam analogs for catalytic applications, in the preparation of molecular magnets, and in supramolecular chemistry as a building block for interlocked molecules. Category: Intermediates. Synonyms: 10-Tetraazacyclododecane. CAS No. 294-90-6. Product ID: INT294906. Molecular formula: C8H20N4. Mole weight: 172.27. EINECS: 608-365-3. InChIKey: QBPPRVHXOZRESW-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Cyclizine Lactate | Cyclizine Lactate is the lactate salt of cyclizine, a first-generation histamine H1 receptor antagonist with prominent antiemetic properties belonging to the piperazine class. The lactate salt form offers distinct solubility characteristics compared to the hydrochloride salt. Applications: Indicated for the prevention and treatment of nausea, vomiting, and motion sickness. cyclizine lactate is a first-generation h1 receptor antagonist with prominent antiemetic properties, effective in postoperative nausea, vestibular disorders, and drug-induced emesis through combined h1 and muscarinic receptor blockade. Category: Active pharmaceutical ingredients. Synonyms: 1-(Diphenylmethyl)-4-methylpiperazine monolactate;Piperazine, 1-(diphenylmethyl)-4-methyl-, mono(2-hydroxypropanoate). CAS No. 5897-19-8. Product ID: API5897198. Molecular formula: C21H28N2O3. Mole weight: 356.5. InChIKey: JOROEVAWQLGPFQ-UHFFFAOYSA-N. | |
| Cycloastragenol | Cycloastragenol, a saponin and aglycone found in Astragalus, is a natural triterpenoid. It has anti-aging properties and can also act as an adjuvant therapy for cancer. Applications: Pharmaceutical industry. Category: Natural extract. Synonyms: (3beta,6alpha,16beta,20R,24S) 20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Astramembrangenin;Cyclosieversigenin;CYCLOASTRAGENOL(SH);Cyclogalegenol. CAS No. 78574-94-4. Product ID: PIPE-0318. Molecular formula: C30H50O5. Mole weight: 490.71. InChIKey: WENNXORDXYGDTP-XWIGRFCYNA-N. Appearance: Powder to crystal. Standard: In house. | |
| Cyclopentolate Hydrochloride | Cyclopentolate Hydrochloride is a synthetic anticholinergic agent of the tropicamide class. It is specifically developed for ophthalmic use, characterized by rapid onset and a comparatively short duration of mydriatic and cycloplegic action relative to atropine. Applications: Used in ophthalmology for diagnostic and therapeutic mydriasis and cycloplegia. cyclopentolate hydrochloride is a short-acting anticholinergic agent that produces rapid pupillary dilation and ciliary muscle paralysis, facilitating fundus examination, retinoscopy, and measurement of refractive errors. Category: Active pharmaceutical ingredients. Synonyms: 2-(dimethylamino)ethyl1-hydroxy-alpha-phenylcyclopentaneacetatehydrochlorid;alpha-(1-hydroxycyclopentyl)-benzeneaceticaci2-(dimethylamino)ethylest;2Chemicalbook-dimethylaminoethyl2-(1-hydroxycyclopentyl)-2-phenylacetatehydrochloride;2-dimethylaminoethyl2-(1-hydroxycyclopentyl)-2-phenyl-ethanoatehydrochloride. CAS No. 5870-29-1. Product ID: API5870291. Molecular formula: C17H26ClNO3. Mole weight: 327.8. EINECS: 227-521-8. InChIKey: RHKZVMUBMXGOLL-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Cyclophosphamide | Cyclophosphamide Monohydrate is an immunosuppressive, cytotoxic apoptosis inducer. Category: Active pharmaceutical ingredients. CAS No. 6055-19-2. Product ID: API6055192. Molecular formula: C7H15Cl2N2O2P H2O. Mole weight: 279.1. Standard: Chinese Pharmacopoeia 2015 Edition Part 2. | |
| Cystorelin | Cystorelin is a synthetic decapeptide gonadotropin-releasing hormone (GnRH) that is chemically identical to the naturally occurring hypothalamic GnRH. It is primarily used in veterinary reproductive medicine and consists of the sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. Applications: Used in veterinary reproductive medicine for estrus synchronization and ovulation induction in cattle. cystorelin is a synthetic gnrh decapeptide chemically identical to native hypothalamic gnrh, designed to stimulate gonadotropin release for controlled breeding programs and reproductive management in livestock. Category: Active pharmaceutical ingredients. Synonyms: (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2-amino-2-oxoethyl)amino]-oChemicalbookxomethyl]-1-pyrrolidinyl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methy;GonadelinAcetate. CAS No. 34973-08-5. Product ID: API34973085. Molecular formula: C57H79N17O15. Mole weight: 1242.3. EINECS: 683-628-3. InChIKey: NGCGMRBZPXEPOZ-HBBGHHHDSA-N. Appearance: White to off-white solid. | |
| Cytarabine Hydrochloride | Cytosine β-D-arabinofuranoside hydrochloride is a DNA synthesis inhibitor and anti-leukemic agent. Category: Active pharmaceutical ingredients. CAS No. 69-74-9. Product ID: API69749. Molecular formula: C9H13N3O5 HCl. Mole weight: 279.68. Appearance: Crystalline powder. Standard: Chinese Pharmacopoeia 2015 Edition Part 2. | |
| Cytisine | Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. It has a role as a nicotinic acetylcholine receptor agonist, a phytotoxin and a plant metabolite. It is an alkaloid, an organic heterotricyclic compound, a secondary amino compound, a lactam and a bridged compound. Applications: Smoking cessation. Category: Natural extract. Synonyms: Baptitoxine. Sophorine. Baptitoxin. CAS No. 485-35-8. Product ID: PIPE-0738. Molecular formula: C11H14N2O. Mole weight: 190.24. EINECS: 207-616-0. SMILES: C1C2CNCC1C3=CC=CC(=O)N3C2. Appearance: Orthorhombic prisms. | |
| Dabrafenib | Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma. Category: Active pharmaceutical ingredients. CAS No. 1195765-45-7. Product ID: API1195765457. Molecular formula: C23H20F3N5O2S2. Mole weight: 519.56. | |
| Dacomitinib | Dacomitinib (PF299)(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively. Category: Active pharmaceutical ingredients. Synonyms: PF-299804, PF-00299804, PF299. Grades: DMF. CAS No. 1110813-31-4. Product ID: API1110813314. Molecular formula: C24H25ClFN5O2. Mole weight: 469.94. Standard: Facility GMP. | |
| Dacomitinib hydrate | Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Category: Active pharmaceutical ingredients. Synonyms: PF 299804. CAS No. 1042385-75-0. Product ID: API1042385750. Molecular formula: C24H27ClFN5O3. Mole weight: 487.96. | |
| Dacomitinib metabolite M2 | Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M. Category: Active pharmaceutical ingredients. Synonyms: Dacomitinib cysteine conjugate,UNII-SOA52D3NLL. CAS No. 1262034-38-7. Product ID: API1262034387. Molecular formula: C27H32ClFN6O4S. Mole weight: 591.1. | |
| Dandelion Root Extract | Dandelion Root Extract is a processed and concentrated extract from the root of the herbaceous flowering plant Taraxacum officinale. It is extremely rich in flavonoids, polysaccharides, phenolic acids, vitamins B, C, E, and minerals. Dandelion Root Extract is a natural rich source of minerals and Omega-3 fatty acids and supports a comprehensive approach to well-being and therapeutic care. Applications: Dandelion root extract is a common nutraceutical ingredient with uses for supporting the liver's detoxification function, for reducing water retention, and for supporting healthy digestion by relieving constipation. in topical applications, the extract can relieve dermatitis and other inflammatory skin conditions, and dry and scaly skin. Category: Natural extract. Product ID: PIPE-0018. | |
| Danofloxacin | Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine. Category: Active pharmaceutical ingredients. Synonyms: Danofloxacine, Danofloxacin free base, Danofloxacino. CAS No. 112398-08-0. Product ID: API112398080. Molecular formula: C19H20FN3O3. Mole weight: 357.38. | |
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