Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Difluprednate | Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain. Category: Active pharmaceutical ingredients. CAS No. 23674-86-4. Product ID: API23674864. Molecular formula: C27H34F2O7. Mole weight: 508.55. |  |
| Dihydro Dutasteride | Dihydro Dutasteride, a metabolite of Dutasteride, effectively inhibits five α-reductase isozymes. Category: Active pharmaceutical ingredients. CAS No. 164656-22-8. Product ID: API164656228. Molecular formula: C27H32F6N2O2. Mole weight: 530.55. | |
| Dihydroergotamine Mesylate | Dihydroergotamine Mesylate is the mesylate salt of dihydroergotamine, a semisynthetic ergot alkaloid. It is formed by hydrogenation of the 9,10-double bond of ergotamine, which reduces its peripheral vasoconstrictive activity while preserving cranial vascular selectivity. Applications: Indicated for the acute treatment of migraine headaches and cluster headaches. dihydroergotamine mesylate is a semisynthetic ergot alkaloid that acts as a 5-ht1b/1d receptor agonist, providing cranial vasoconstriction with reduced peripheral vascular effects compared to ergotamine. Category: Active pharmaceutical ingredients. Synonyms: 5'-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman;9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trionemonomethanesulfonate. CAS No. 6190-39-2. Product ID: API6190392. Molecular formula: C34H41N5O8S. Mole weight: 679.8. EINECS: 228-235-6. InChIKey: ADYPXRFPBQGGAH-UMYZUSPBSA-N. Appearance: White powder. | |
| Dimenhydrinate | Dimenhydrinate is a salt complex of 8-chlorotheophylline and diphenhydramine, combining the antihistamine properties of diphenhydramine with the mild stimulant properties of 8-chlorotheophylline. This combination is used to prevent and treat motion sickness, nausea, and vomiting. The 8-chlorotheophylline component reduces the sedation associated with diphenhydramine alone while contributing to an antiemetic effect through adenosine antagonism in the vestibular system. Applications: Dimenhydrinate is indicated for the prevention and treatment of motion sickness (car, sea, air travel), radiation sickness, and postoperative nausea and vomiting (ponv). it is also used for the symptomatic treatment of vertigo associated with meniere's disease and other vestibular disorders. Category: Active pharmaceutical ingredients. Synonyms: 2-(benzhydryloxy)-n,n-dimethylethylamine 8-chlorotheophyllinate;8-chloro-3,7-dihydro-1,3-dimethyl-1h-purine-2,6-dione compound with 2-(diphenylmethoxy)-n,n-dimethylethanamine. CAS No. 523-87-5. Product ID: API523875. Molecular formula: C24H28ClN5O3. Mole weight: 469.97. EINECS: 208-350-8. InChIKey: NFLLKCVHYJRNRH-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Dimethicone, viscosity 10 | Dimethicone, viscosity 10. Applications: Dimethicone is commonly used in skin and hair products. Category: Pharmaceutical excipients. Synonyms: SILCOREL(R) ADP1000 ANTIFOAM COMPOUND;SILICONE OIL DC 200;REDUCED VOLATILITY POLYDIMETHYLSILOXANE;POLYDIMETHYLSILOXANE 158'000;POLYDIMETHYLSILOXANE 16'000;POLYDIMETHYLSILOXANE 173'000;POLYDIMETHYLSILOXANE 1'850;POLYDIMETHYLSILOXANE 197'000. CAS No. 9006-65-9. Product ID: PIE-0071. Molecular formula: (C2?H6?OSi)n?. Appearance: Colourless Oil. Standard: ChP/NF/EP/JP. | |
| Dimethyl Sulfoxide (DMSO) | Dimethyl sulfoxide (DMSO) is a sulfur-containing organic solvent that is commonly described as a "universal solvent" due to its broad solvating capability. It is a colorless, transparent liquid at room temperature and is one of the most polar aprotic solvents with a high boiling point and water miscibility and it can also dissolve in most organic solvents (such as alcohols, ethers, chloroform). Its dissolving power has made it the solvent of choice for many organic compounds, polymers, peptides, and many inorganic salts. Applications: Dimethyl sulfoxide is used in a wide variety of applications. its primary use is as a solvent and reaction medium in chemical industries, a direct material and drug carrier/vehicle for pharmaceutical industries and a cryoprotectant in cell biology, which is used to freeze and store primary cells/cell lines, embryonic stem cells and hematopoietic stem cells safely. Category: Solvents. Synonyms: DMSO. CAS No. 67-68-5. Product ID: CHE67685. Molecular formula: C2H6OS. Mole weight: 78.13. EINECS: 200-664-3. InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N. Appearance: Colorless liquid. | |
| Dinoprostone (Prostaglandin E2) | Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour. Category: Active pharmaceutical ingredients. Synonyms: Prostaglandin E2. Dinoprostone. PGE2. Prostin E2. CAS No. 363-24-6. Product ID: API363246. Molecular formula: C20H32O5. Mole weight: 352.5. EINECS: 206-656-6. SMILES: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O. Appearance: White Solid. | |
| Dinoprost Tromethamine | Dinoprost Tromethamine is a synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum. Category: Active pharmaceutical ingredients. Synonyms: Dinolytic. Dinoprost trometamol. Zinoprost. CAS No. 38562-01-5. Product ID: API38562015. Molecular formula: C24H45NO8. Mole weight: 475.6. EINECS: 254-002-3. SMILES: CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O.C(C(CO)(CO)N)O. Appearance: white to off-white, very hygroscopic, crystalline powder. | |
| Diosmetin | Diosmetin is a flavonoid that impedes human CYP1A enzyme activity and has anti-mutagenic and anti-allergenic properties. Category: Active pharmaceutical ingredients. CAS No. 520-34-3. Product ID: API520343. Molecular formula: C16H12O6. Mole weight: 300.263. | |
| Dipotassium Hydrogen Phosphate Trihydrate | Dipotassium Hydrogen Phosphate Trihydrate is commonly used as a buffering agent. Category: Other apis. Synonyms: Dipotassium hydrogen phosphate trihydrate. Potassium phosphate dibasic trihydrate. Potassium phosphate, dibasic, trihydrate. di-Potassium hydrogen phosphate trihydrate. CAS No. 16788-57-1. Product ID: API16788571. Molecular formula: H7K2O7P. Mole weight: 228.22. EINECS: 605-492-6. SMILES: O.O.O.OP(=O)([O-])[O-].[K+].[K+]. Appearance: Colorless or White Powder or Crystals. | |
| Dipropylene glycol monomethyl ether (DPM) | DPM is used as solvent for PVC stabilizer, nitrocellulose, ethyl cellulose, polyvinyl acetate, solvent for paint and dyestuff, and an ingredient of brake fluid. It can be used as solvent of printing ink, enamel paint, cutting fluid and operating oil; as coupling agent of water-based paint (usually used by mixing up); as active solvent of water-based paint; as solvent and coupling agent of household and industrial cleanser, remover for grease and paint, cleanser for metal and hard surface; as base solvent and coupling agent of solvent-type silk-screen printing ink; as solvent and coupling agent of vat dye textile; as coupling agent and skin-care agent in cosmetic formula; as stabilizer of pesticide and coagulating?agent of floor brightener. Category: Chemicals. Synonyms: (2-methoxymethylethoxy)-propano. 1-(2-methoxy-1-methylethoxy)-2-propanol. 1-(2-methoxyisopropoxy)-2-propanol. CAS No. 34590-94-8. Product ID: CHE34590948. Molecular formula: CH3OC3H6OC3H6OH. Mole weight: 148.2. SMILES: CCC(O)OCCCOC. Appearance: Colorless and transparent liquid. | |
| Diquafosol Sodium | Diquafosol tetrasodium, also referred to Diquas, is a P2Y2 receptor agonist that is targeted to treat dry eye disease through rehydration of the ocular surface. Category: Ophthalmic apis. Synonyms: Ins 365. Diquafosol sodium. INS365. CAS No. 211427-08-6. Product ID: API211427086. Molecular formula: C18H22N4Na4O23P4. Mole weight: 878.2. SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O)O.[Na+].[Na+].[Na+].[Na+]. | |
| Dirithromycin | Dirithromycin is a semi-synthetic derivative of Erythromycin, and an antibacterial. The compound is a more lipid soluble prodrug of 9S-erythromycyclamine. Category: Active pharmaceutical ingredients. CAS No. 62013-04-1. Product ID: API62013041. Molecular formula: C42H78N2O14. Mole weight: 835.074. Appearance: Crystalline powder. Standard: USP/EP. | |
| Disodium Edetate | Disodium edetate (Disodium EDTA) is a white crystalline powder. It is used mainly as a chelating agent. It is the disodium salt of ethylenediaminetetraacetic acid. Its unique property is that it will "sequestrate" ("grab") polyvalent metal ions (ions of metals like calcium, magnesium, and iron) and hold them tightly in water-soluble complexes. It essentially "clamps" the metal ion so it cannot take part in reactions with other constituents of the mixture. Applications: Disodium edetate has many uses within industry, most notably pharmaceutical, cosmetics, and food. pharmaceutical uses include its employment in chelation therapy for heavy metal poisonings and as an anticoagulant additive to blood samples (it binds calcium ions preventing clotting). cosmetic uses include regular appearances in shampoos and lotions as a preservative enhancer since metals can cause products to change color or turn rancid. disodium edetate is also commonly found as a food additive, where it acts as a stabilizer, preventing shifts in color and flavor of canned goods and carbonated beverages. Category: Chelating agents. Synonyms: EDTA disodium salt; Disodium dihydrogen ethylenediaminetetraacetate dihydrate; ethylenediaminetetraacetic acid disodium dihydrate; Edta disodium. CAS No. 6381-92-6. Product ID: PIE-0151. Molecular formula: C10H18N2Na2O10. Mole weight: 372.24. InChIKey: OVBJJZOQPCKUOR-UHFFFAOYSA-L. | |
| DL-Alanine | Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system. Category: Amino acids and derivatives. Synonyms: alanine. 2-Aminopropanoic acid. DL-2-Aminopropionic acid. CAS No. 302-72-7. Product ID: API302727. Molecular formula: C3H7NO2. Mole weight: 89.09. EINECS: 206-126-4. SMILES: CC(C(=O)O)N. Appearance: White crystalline powder. Standard: USP,AJI. | |
| DL-Panthenol | DL-Panthenol(Provitamin B5) is the Pro-vitamin of D-Pantothenic acid (Vitamin B5) for using in hair, skin and nail care products. DL-Panthenol is a racemic mixture of D.Panthenol and L-Panthenol.DL Panthenol, is a well known hair conditioner which restores shine & luster to dull hair while also improve tensile strength. Additional.DL. Panthenol is a skin conditioning agent & effective moisturizer. Category: Cosmetic ingredients and additives. CAS No. 16485-10-2. Product ID: CIA16485102. | |
| D-Luciferin | D-Luciferin has been used in the preparation of the reaction mixture for nitric oxide determination by minescence measurement. It has also been used in the preparation of D-luciferin stock solution for luciferin assays. Category: Intermediates. Synonyms: 4,5-DIHYDRO-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-4-THIAZOLECARBOXY;4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLE-CARBOXYLIC ACID;4,5-DIHYDRO-(6-HYDROXY-2-BENZOTHIAZOYL)-4-THIAZOLE CARBOXYLIC ACID;LUCIFERIN, D-;LUCIFERIN;D(-)-2-(6'-HYDROXY-BENZOTHIAZOLYL)-DELTA2-THIAZOLINE-4-CARBOXYLIC ACID;D(-)-LUCIFERIN;D-LUCIFERIN. CAS No. 2591-17-5. Product ID: INT2591175. Molecular formula: C11H8N2O3S2. Mole weight: 280.32. EINECS: 219-981-3. SMILES: S1C[C@H](C(O)=O)N=C1C1=NC2=CC=C(O)C=C2S1. InChIKey: BJGNCJDXODQBOB-SSDOTTSWSA-N. Appearance: Powder. | |
| D-Mabuterol hydrochloride | D-Mabuterol hydrochloride is a D isoform of Mabuterol, which is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors. Category: Active pharmaceutical ingredients. CAS No. 95656-54-5. Product ID: API95656545. Molecular formula: C13H19Cl2F3N2O. Mole weight: 347.2. | |
| Dobutamine Hydrochloride | Dobutamine hydrochloride is a synthetic catecholamine and direct-acting inotropic agent administered as a continuous intravenous infusion for short-term management of cardiac decompensation. As a racemic mixture of enantiomers, dobutamine is structurally related to dopamine but designed specifically to increase cardiac contractility with minimal direct vasoconstriction. Applications: Dobutamine hydrochloride is indicated for patients requiring positive inotropic support in cardiac decompensation due to depressed contractility, including low cardiac output states following myocardial infarction, cardiac surgery, or in cardiogenic and septic shock. it is also utilized for dobutamine stress echocardiography to detect myocardial ischemia in patients unable to undergo exercise testing. Category: Apis for chronic cardiac insufficiency. Synonyms: Dobutamine Hcl; 4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol;hydrochloride. CAS No. 49745-95-1. Product ID: API0231680. Molecular formula: C18H24ClNO3. Mole weight: 337.8. EINECS: 256-464-1. InChIKey: BQKADKWNRWCIJL-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| Docosanol | Docosanol is a saturated aliphatic alcohol with a 22-carbon chain (behenyl alcohol) that functions as a topical antiviral agent. Unlike classic nucleoside analog antivirals, its mechanism is independent of viral enzymes, and it is classified as a fusion inhibitor. The compound is formulated in cream preparations for the topical treatment of herpes labialis (cold sores). Applications: Docosanol is indicated for the topical treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents. applied early at the first signs of a cold sore outbreak (tingling, redness), it reduces the duration of symptoms and accelerates healing time. Category: Active pharmaceutical ingredients. Synonyms: n-Docosanol;Docosan-1-ol. CAS No. 661-19-8. Product ID: API661198. Molecular formula: C22H46O. Mole weight: 326.6. EINECS: 211-546-6. InChIKey: NOPFSRXAKWQILS-UHFFFAOYSA-N. Appearance: White solid. | |
| Docusate Sodium | Doxacurium chloride is a potent non-depolarizing neuromuscular blocking agent. Doxacurium chloride binds to cholinergic receptors to antagonize acetylcholine, resulting in a block of neuromuscular transmission. Doxacurium chloride can be used for the research of neurological diseases. Category: Active pharmaceutical ingredients. CAS No. 106819-53-8. Product ID: API106819538. Molecular formula: C56H78Cl2N2O16. Mole weight: 1106.13. Standard: USP/EP. | |
| Dolutegravir O-β-D-Glucuronide | Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir. Category: Active pharmaceutical ingredients. CAS No. 1485692-21-4. Product ID: API1485692214. Molecular formula: C26H27F2N3O11. Mole weight: 595.509. | |
| Dolutegravir RR Isomer | Dolutegravir RR Isomer is an isomer of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Category: Active pharmaceutical ingredients. CAS No. 1357289-29-2. Product ID: API1357289292. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Dolutegravir sodium | Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. Category: Active pharmaceutical ingredients. CAS No. 1051375-19-9. Product ID: API1051375199. Molecular formula: C20H18F2N3NaO5. Mole weight: 441.36. | |
| Dolutegravir SR Isomer | Dolutegravir SR Isomer is an isomeric derivative of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Category: Active pharmaceutical ingredients. CAS No. 1309560-49-3. Product ID: API1309560493. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Donafenib | Donafenib (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively). Category: Active pharmaceutical ingredients. CAS No. 1130115-44-4. Product ID: API1130115444. Molecular formula: C21H13ClD3F3N4O3. Mole weight: 467.84. | |
| Dopamine Hydrochloride | Dopamine hydrochloride is the hydrochloride salt form of dopamine, a naturally occurring catecholamine that acts as both an endogenous neurotransmitter and a synthetic cardiotonic agent. It is supplied as a sterile, clear practically colorless concentrate solution for intravenous infusion in single-dose vials containing 40 mg/mL to 80 mg/mL concentrations. It serves as a precursor to norepinephrine and epinephrine in the body and is classified as a prescription drug used exclusively in intensive care settings. Applications: Dopamine hydrochloride is indicated to improve hemodynamic status in patients with distributive shock or shock due to reduced cardiac output, including cardiogenic, septic, and traumatic shock. it is contraindicated in pheochromocytoma and requires correction of hypovolemia, acidosis, and hypoxia prior to administration to prevent severe tissue ischemia and gangrene from extravasation. Category: Other apis. Synonyms: Dopamine HCl, Cardiosteril, 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride. CAS No. 62-31-7. Product ID: API0232360. Molecular formula: C8H11NO2·HCl. Mole weight: 189.64. EINECS: 200-527-8. InChIKey: CTENFNNZBMHDDG-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| Doravirine | Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor used for the treatment of HIV/AIDS. Category: Active pharmaceutical ingredients. CAS No. 1338225-97-0. Product ID: API1338225970. Molecular formula: C17H11ClF3N5O3. Mole weight: 425.75. | |
| Doxepin Hydrochloride | Doxepin Hydrochloride is a tricyclic compound belonging to the dibenzoxepin class. It is a dual serotonin and norepinephrine reuptake inhibitor that also exhibits antagonist activity at histamine H1, muscarinic, and alpha-1 adrenergic receptors, giving it a broad multi-receptor pharmacological profile. Applications: Used in the treatment of depression and anxiety disorders. doxepin hydrochloride is a tricyclic antidepressant indicated for major depressive disorder, neurotic depression, and depression accompanied by anxiety. it also demonstrates efficacy in insomnia management, pruritus treatment, and urticaria associated with psychogenic factors. Category: Active pharmaceutical ingredients. Synonyms: 11-(3-DIMETHYLAMINOPROPYLIDENE)-6,11-DIHYDRODIBENZ[B,E]OXEPIN HYDROCHLORIDE;Doxepine hydrochloride;1-Propanamine, 3-dibenzb,eoxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride. CAS No. 1229-29-4. Product ID: API1229294. Molecular formula: C19H22ClNO. Mole weight: 315.8. EINECS: 214-966-8. InChIKey: MHNSPTUQQIYJOT-SJDTYFKWSA-N. Appearance: White to off-white powder. | |
| Doxercalciferol | It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease. It has a role as a provitamin, a bone density conservation agent and a prohormone. Category: Active pharmaceutical ingredients. Synonyms: 1-Hydroxyergocalciferol. Hectorol. 1alpha-Hydroxyergocalciferol. CAS No. 54573-75-0. Product ID: API54573750. Molecular formula: C28H44O2. Mole weight: 412.6. EINECS: 643-005-9. SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C. Appearance: White Solid. | |
| Doxylamine Succinate | Doxylamine Succinate is a first-generation histamine H1 receptor antagonist (antihistamine) of the ethanolamine class, structurally related to diphenhydramine. The succinate salt is used for improved aqueous solubility and is characterized by its high potency and long duration of action. As a sedating antihistamine, it crosses the blood-brain barrier and exerts significant central nervous system depressant effects. Applications: Doxylamine succinate is indicated for the symptomatic relief of seasonal and perennial allergic rhinitis, allergic conjunctivitis, urticaria, and other allergic skin reactions. it is also widely used in over-the-counter sleep aids due to its pronounced sedative properties and in antiemetic products for the prevention and treatment of nausea and vomiting of pregnancy. Category: Active pharmaceutical ingredients. Synonyms: 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-pyridinsuccinate(1;2-(alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl)pyridinesuccinate;2-dimethylaminoethoxyphenylmethyl-2-picolinesuccinate. CAS No. 562-10-7. Product ID: API562107. Molecular formula: C21H28N2O5. Mole weight: 388.5. EINECS: 209-228-7. InChIKey: KBAUFVUYFNWQFM-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| D-ribose | D-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. Category: Natural extract. Synonyms: RIBONIC ACID-Gamma-LACTONE, D-(+)-(RG);D-Ribose/D(-)-Ribose. CAS No. 50-69-1. Product ID: PIPE-0277. Molecular formula: C5H10O5. Mole weight: 150.13. EINECS: 200-059-4. InChIKey: HMFHBZSHGGEWLO-SOOFDHNKSA-N. Appearance: Crystalline Powder. Standard: USP. | |
| Droperidol | Droperidol is a butyrophenone first-generation antipsychotic with a primary mechanism of action as a central dopamine D2-receptor antagonist. It was approved by the FDA in 1971 for the treatment of nausea, vomiting, anxiety, and sedation. Applications: In the emergency department, droperidol is used to manage acute agitation, headaches, nausea, vomiting, and vertigo. for chemical sedation of the agitated patient, it has a rapid onset and is more effective and faster than haloperidol. it is also an effective antiemetic in postoperative and emergent settings, and is a potent treatment for acute headaches and vertigo. Category: Active pharmaceutical ingredients. Synonyms: Droleptan; Dehydrobenzperidol; Inapsine; Dridol; Properidol; Sintodril; Sintosian. CAS No. 548-73-2. Product ID: API548732. Molecular formula: C22H22FN3O2. Mole weight: 379.4. EINECS: 208-957-8. InChIKey: RMEDXOLNCUSCGS-UHFFFAOYSA-N. Appearance: White to light yellow crystalline powder. | |
| drostanolone enanthate | Drostanolone enanthate is an anabolic steroid that belongs to the class of androgenic hormones. It is a synthetic derivative of dihydrotestosterone (DHT) and has potent anticancer activity against prostate carcinoma cells. Drostanolone enanthate inhibits the growth of cancer cells by binding to the androgen receptor, which is located in the cytoplasm. This causes a conformational change in the receptor that prevents it from interacting with DNA. Drostanolone enanthate also inhibits fatty acid synthesis and microbial biotransformation, which may have anticancer effects. Category: Active pharmaceutical ingredients. CAS No. 13425-31-5. Product ID: API13425315. Molecular formula: C27H44O3. Mole weight: 416.6. | |
| Dulaglutide | Dulaglutide, a GLP-1 receptor agonist that is administered subcutaneously once weekly, has been approved since 2014 for the treatment of adults with type 2 diabetes. Category: Active pharmaceutical ingredients. CAS No. 923950-08-7. Product ID: API923950087. EINECS: 200-001-8. Appearance: Colorless to light yellow liquid. | |
| Duloxetine Hydrochloride | Duloxetine hydrochloride is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) approved for major depressive disorder, generalized anxiety disorder, and chronic pain conditions. The drug is structurally distinct from venlafaxine and has a more balanced dual reuptake inhibition profile. Applications: Duloxetine is indicated for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal pain (including chronic low back pain and osteoarthritis pain), and stress urinary incontinence in women. it is also used off-label for chemotherapy-induced peripheral neuropathy. Category: Active pharmaceutical ingredients. Synonyms: Duloxetine HCl; Ariclaim; Duloxetine mylan; LY248686 HCl. CAS No. 136434-34-9. Product ID: API136434349. Molecular formula: C18H20ClNOS. Mole weight: 333.9. EINECS: 603-962-5. InChIKey: BFFSMCNJSOPUAY-LMOVPXPDSA-N. Appearance: White to off-white crystalline powder. | |
| EBI-907 | EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). Category: Active pharmaceutical ingredients. CAS No. 1581764-31-9. Product ID: API1581764319. Molecular formula: C23H21ClF2N4O3S. Mole weight: 506.95. | |
| ecenofloxacin | Ecenofloxacin is a fluoroquinolone antibacterial with potent antibacterial activities against Gram-positive, Gram-negative, and anaerobic organisms. Category: Active pharmaceutical ingredients. CAS No. 162301-05-5. Product ID: API162301055. Molecular formula: C19H21FN4O3. Mole weight: 372.39. | |
| Echothiophate Iodide | Echothiophate iodide is a potent, long-acting organophosphate compound used as a miotic agent in ophthalmology.As an irreversible cholinesterase inhibitor, it represents one of the most potent classes of glaucoma medications, though its use has significantly declined with the advent of safer agents. Applications: Echothiophate iodide is indicated for the treatment of open-angle glaucoma and accommodative esotropia. in glaucoma management, it provides effective round-the-clock intraocular pressure control, though it is now reserved for refractory cases due to its side effect profile. for accommodative esotropia in pediatric patients, it is used diagnostically and therapeutically to correct ocular deviation. Category: Ophthalmic apis. Synonyms: (2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate; O,O-diethyl S-2-trimethylammonium ethylphosphonothiolate iodide. CAS No. 513-10-0. Product ID: API0231647. Molecular formula: C9H23INO3PS. Mole weight: 383.2. EINECS: 208-152-1. InChIKey: OVXQHPWHMXOFRD-UHFFFAOYSA-M. | |
| Ecnoglutide | Ecnoglutide is a novel, long-acting glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes and obesity. It is a synthetic peptide analog composed entirely of natural amino acids, which simplifies its manufacturing process. Applications: Ecnoglutide is indicated to improve glycemic control in adults with type 2 diabetes and for chronic weight management in individuals with obesity or overweight with comorbidities. Category: Peptide apis. Synonyms: Ecnoglutide [INN], UNII-KM6YM7L8LH, KM6YM7L8LH. CAS No. 2459531-73-6. Product ID: API0233394. Molecular formula: C194H304N48O61. Mole weight: 4285. InChIKey: DJMLKAVQDZZBNC-NYHUXPQOSA-N. | |
| Edetate Calcium Disodium | Edetate Calcium Disodium (Calcium Disodium EDTA) is a chelating agent consisting of calcium bound to ethylenediaminetetraacetic acid (EDTA). Unlike the disodium salt, this form provides calcium displacement chelation therapy without causing hypocalcemia. It has been used clinically for the treatment of heavy metal poisoning and is recognized in pharmaceutical compounding. Applications: Edetate calcium disodium is indicated for the treatment of lead poisoning, including both acute and chronic lead toxicity, and may be used as an adjunct in the management of other heavy metal intoxications. administration is typically by intravenous infusion. it is also used as a sequestrant and stabilizer in certain pharmaceutical formulations and food products. Category: Active pharmaceutical ingredients. Synonyms: EDTA DISODIUM-CALCIUM SALT. CAS No. 62-33-9. Product ID: API62339. Molecular formula: C10H12CaN2Na2O8. Mole weight: 374.27. EINECS: 200-529-9. InChIKey: SHWNNYZBHZIQQV-UHFFFAOYSA-J. Appearance: White powder. | |
| Edrophonium Chloride | Edrophonium chloride is a short-acting, reversible acetylcholinesterase inhibitor with a rapid onset (30 to 60 seconds) and brief duration of action (5 to 10 minutes). It is administered intravenously and is chemically classified as a quaternary ammonium compound, limiting its penetration into the central nervous system. Applications: Edrophonium was historically used as the "tensilon test" to diagnose myasthenia gravis, where a brief improvement in muscle strength following administration supported the diagnosis. it has also been employed to distinguish myasthenic crisis from cholinergic crisis. today, modern diagnostic tools such as antibody testing and electromyography have largely replaced its diagnostic use, though it remains available for selected neuromuscular assessments. Category: Active pharmaceutical ingredients. Synonyms: Antirex; Enlon; Reversol; Edrophonii chloridum; Cloruro de edrofonio; Chlorure d'edrophonium; Ethyl(m-hydroxyphenyl)dimethylammonium chloride; N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride. CAS No. 116-38-1. Product ID: API0231580. Molecular formula: C10H16ClNO. Mole weight: 201.69. EINECS: 204-138-4. InChIKey: BXKDSDJJOVIHMX-UHFFFAOYSA-N. Appearance: White or almost white crystalline powder. | |
| Efavirenz | Efavirenz (DMP 266) is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor, acting as a Non-Nucleoside Reverse Transcriptase Inhibitor, Cytochrome P450 3A Inducer, Cytochrome P450 2B6 Inducer, Cytochrome P450 2C9 Inhibitor, Cytochrome P450 2C19 Inhibitor, and Cytochrome P450 3A4 Inhibitor, classified as a Non-Nucleoside Analog. Category: Active pharmaceutical ingredients. CAS No. 154598-52-4. Product ID: API154598524. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Efavirenz, (R)- | Efavirenz, (R)- is an antiviral agent and a nonnucleoside HIV-1 reverse transcriptase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 154801-74-8. Product ID: API154801748. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| Efinaconazole | Efinaconazole (KP-103)(KP-103) is an Azole Antifungal currently under development as a topical treatment for onychomycosis. Category: Active pharmaceutical ingredients. CAS No. 164650-44-6. Product ID: API164650446. Molecular formula: C18H22F2N4O. Mole weight: 348.39. | |
| Eflornithine | Eflornithine (DFMO) is a selective and orally available ornithine decarboxylase inhibitor that delays hair overgrowth.Eflornithine is used in the study of African trypanosomiasis, malignant glioma, and sleeping sickness. Category: Active pharmaceutical ingredients. CAS No. 70052-12-9. Product ID: API70052129. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
| Eflornithine hydrochloride | Eflornithine hydrochloride, a specific and irreversible inhibitor of ornithine decarboxylase enzyme, is a medication used for the treatment of African trypanosomiasis and excessive facial hair growth in women. Category: Active pharmaceutical ingredients. CAS No. 68278-23-9. Product ID: API68278239. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63. | |
| Eflornithine hydrochloride hydrate | Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific and irreversible inhibitor of theornithine decarboxylase (ODC). Category: Active pharmaceutical ingredients. Synonyms: Difluoromethylornithine hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate, Eflornithine hydrochloride, MDL-71782 hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, Eflornithine hydrochloride Monohydrate. CAS No. 96020-91-6. Product ID: API96020916. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
| Elastin | Elastin. Category: Natural extract. CAS No. 9007-58-3. Product ID: PIPE-0134. Molecular formula: C27H48N6O6. Mole weight: 552.7. EINECS: 232-701-4. InChIKey: DPUYCSDGMSDKKV-XPEWSIIXNA-N. Appearance: Powder. Standard: In house. | |
| Elexacaftor | Elexacaftor (VX-445)is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It promotes the processing and trafficking of CFTR, increases the amount of CFTR on the cell surface, and improves the processing and trafficking of Phe508del CFTR protein. Category: Active pharmaceutical ingredients. CAS No. 2216712-66-0. Product ID: API2216712660. Molecular formula: C26H34F3N7O4S. Mole weight: 597.65. | |
| Eliglustat | Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease. Category: Active pharmaceutical ingredients. Synonyms: Genz-99067. Genz 99067. GENZ-112638. CAS No. 491833-29-5. Product ID: API491833295. Molecular formula: C23H36N2O4. Mole weight: 404.5. SMILES: CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O. Appearance: Solid powder. | |
| Elotuzumab | Elotuzumab(HuLuc 63) is a monoclonal antibody that targets the SLAMF7 receptor.Elotuzumab is a compound that directly activates NK cells and induces antibody-dependent cytotoxicity, and can be used in combination with lenalidomide and dexamethasone (Ld) to treat multiple myeloma. Category: Active pharmaceutical ingredients. CAS No. 915296-00-3. Product ID: API915296003. Mole weight: 145.4 kDa. | |
| ElsulfavirineElpida, VM-1500 | Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug. Category: Active pharmaceutical ingredients. CAS No. 868046-19-9. Product ID: API868046199. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. | |
| Eltrombopag Olamine | Eltrombopag is a is an agonist of the c-mpl (TpoR) receptor used as treatment for thrombocytopenia.It has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). Category: Other apis. Synonyms: Promacta. Revolade. UNII-4U07F515LG. CAS No. 496775-62-3. Product ID: API496775623. Molecular formula: C29H36N6O6. Mole weight: 564.6. SMILES: CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C.C(CO)N.C(CO)N. Appearance: White solid powder. | |
| Emedastine Difumarate | Emedastine difumarate is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine difumarate is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis. Category: Active pharmaceutical ingredients. CAS No. 87233-62-3. Product ID: API87233623. Molecular formula: C25H34N4O9. Mole weight: 534.559. Standard: USP/EP. | |
| Emtricitabine | Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity, with an EC50 value of 0.01 μM in PBMC cells, and can be used to study HIV infection. Category: Active pharmaceutical ingredients. Synonyms: FTC, Emtriva, BW1592. CAS No. 143491-57-0. Product ID: API143491570. Molecular formula: C8H10FN3O3S. Mole weight: 247.25. | |
| Emtricitabine S-oxide | Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine. Category: Active pharmaceutical ingredients. Synonyms: Emtricitabine Degradant-III, Emtricitabine sulfoxide. CAS No. 152128-77-3. Product ID: API152128773. Molecular formula: C8H10FN3O4S. Mole weight: 263.25. | |
| Emtricitabine triphosphate | Emtricitabine triphosphate ((-)-Emtricitabine triphosphate), the phosphorylated anabolite of Emtricitabine, is a nucleoside reverse transcriptase inhibitor and antiretroviral agent effective against HIV and HBV. Category: Active pharmaceutical ingredients. CAS No. 145819-92-7. Product ID: API145819927. Molecular formula: C8H13FN3O12P3S. Mole weight: 487.19. | |
| Enasidenib | Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity. Category: Active pharmaceutical ingredients. CAS No. 1446502-11-9. Product ID: API1446502119. Molecular formula: C19H17F6N7O. Mole weight: 473.38. | |
| Enasidenib mesylate | Enasidenib mesylate (AG-221 mesylate) is a potent and selective IDH2 mutase inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia. Category: Active pharmaceutical ingredients. Synonyms: AG221 mesylate. CAS No. 1650550-25-6. Product ID: API1650550256. Molecular formula: C20H21F6N7O4S. Mole weight: 569.48. | |
| Encorafenib | Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity. Category: Active pharmaceutical ingredients. CAS No. 1269440-17-6. Product ID: API1269440176. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.01. | |
| Enflurane | Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry. It allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. Category: Active pharmaceutical ingredients. CAS No. 13838-16-9. Product ID: API13838169. Molecular formula: C3H2ClF5O. Mole weight: 184.49. | |
| Enfuvirtide | Enfuvirtide is an anti-HIV-1 fusion inhibitor peptide. Category: Active pharmaceutical ingredients. CAS No. 159519-65-0. Product ID: API159519650. Molecular formula: C204H301N51O64. Mole weight: 4491.88. | |
| Enoxacin | Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid. Category: Active pharmaceutical ingredients. CAS No. 74011-58-8. Product ID: API74011588. Molecular formula: C15H17FN4O3. Mole weight: 320.32. | |
| Enoxacin hydrate | Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent. Category: Active pharmaceutical ingredients. CAS No. 84294-96-2. Product ID: API84294962. Molecular formula: C15H17FN4O3·3/2H2O. Mole weight: 347.34. | |
| Enrofloxacin-d5 | Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Category: Active pharmaceutical ingredients. CAS No. 1173021-92-5. Product ID: API1173021925. Molecular formula: C19H17D5FN3O3. Mole weight: 364.43. | |
| Enrofloxacin monohydrochloride | Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is a potent antibiotic with a minimum inhibitory concentration (MIC 90) of 0.312 μg/mL against Mycoplasma bovis, and it also exhibits inhibitory activity against the vaccinia virus (VV). Category: Active pharmaceutical ingredients. CAS No. 93106-59-3. Product ID: API93106593. Molecular formula: C19H23ClFN3O3. Mole weight: 395.86. | |
| Ensartinib | Ensartinib (X-396) is a potent dual ALK/MET inhibitor with IC50 values of. Category: Active pharmaceutical ingredients. CAS No. 1370651-20-9. Product ID: API1370651209. Molecular formula: C26H27Cl2FN6O3. Mole weight: 561.44. | |
| Ensartinib hydrochloride | Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of. Category: Active pharmaceutical ingredients. CAS No. 2137030-98-7. Product ID: API2137030987. Molecular formula: C26H29Cl4FN6O3. Mole weight: 634.36. | |
| Entecavir | Entecavir is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. Category: Active pharmaceutical ingredients. CAS No. 142217-69-4. Product ID: API142217694. Molecular formula: C12H15N5O3. Mole weight: 277.28. | |
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