Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Avarofloxacin | Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug under development for treating acute bacterial skin and skin structure infections, as well as community-acquired pneumonia. Category: Active pharmaceutical ingredients. CAS No. 878592-87-1. Product ID: API878592871. Molecular formula: C21H23F2N3O4. Mole weight: 419.42. |  |
| Avatrombopag Meleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Category: Other apis. Synonyms: E5501 MALEATE. UNII-GDW7M2P1IS. GDW7M2P1IS. CAS No. 677007-74-8. Product ID: API677007748. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. EINECS: 973-683-4. SMILES: C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl.C(=CC(=O)O)C(=O)O. | |
| Avobenzone | Avobenzone, also known as butyl methoxydibenzoylmethane, is an organic sunscreen agent of the dibenzoylmethane class. It is the most widely used UVA I filter (340-400 nm) in broad-spectrum sunscreen formulations and exists in an enol-keto tautomeric equilibrium that is key to its UV absorption mechanism. Applications: Used in broad-spectrum sunscreen formulations for uva i photoprotection. avobenzone is the most widely used organic uva filter covering the 340-400 nm range, providing essential protection against deep skin penetration and photoaging caused by long-wave ultraviolet radiation. Category: Active pharmaceutical ingredients. Synonyms: 4-tert-butyl-4'-methoxy-dibenzoylmethane;4-T-BUTYL-4'-METHOXY-DIBENZOYLMETHANE;1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione. CAS No. 70356-09-1. Product ID: API70356091. Molecular formula: C20H22O3. Mole weight: 310.4. EINECS: 274-581-6. InChIKey: XNEFYCZVKIDDMS-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Axitinib | Inhibits VEGFR1, VEGFR2, VEGFR3, c-kit and PDGFR tyrosine kinases. Category: Active pharmaceutical ingredients. CAS No. 319460-85-0. Product ID: API319460850. Molecular formula: C22H18N4OS. Mole weight: 386.47. | |
| Azacitidine | Azacitidine is a pyrimidine nucleoside analogue of cytidine, classified as a nucleoside metabolic inhibitor with antineoplastic activity. It was initially FDA-approved in 2004 for adult myelodysplastic syndromes and subsequently approved for pediatric juvenile myelomonocytic leukemia in 2022. Applications: Azacitidine is indicated for adult patients with myelodysplastic syndrome subtypes including refractory anemia, refractory anemia with excess blasts, and chronic myelomonocytic leukemia. it is also indicated for pediatric patients aged one month and older with newly diagnosed juvenile myelomonocytic leukemia. Category: Anti-tumor apis. Synonyms: 5-azacytidine, Ladakamycin. CAS No. 320-67-2. Product ID: API0232320. Mole weight: 244.2. EINECS: 206-280-2. InChIKey: NMUSYJAQQFHJEW-KVTDHHQDSA-N. Appearance: White crystalline powder. | |
| Azathioprine Sodium | Azathioprine Sodium is an immunosuppressive antimetabolite that functions as a prodrug of 6-mercaptopurine (6-MP). Administered in its sodium salt form to improve solubility, it is widely used in both organ transplantation and the treatment of autoimmune diseases. As an imidazoline derivative of 6-mercaptopurine, it interferes with purine nucleotide synthesis and lymphocyte proliferation. Applications: Azathioprine sodium is used as an immunosuppressive agent in organ transplantation (renal, hepatic, cardiac) for the prevention of allograft rejection, and in the management of autoimmune conditions including systemic lupus erythematosus (sle), rheumatoid arthritis, crohn's disease, and ulcerative colitis. Category: Active pharmaceutical ingredients. Synonyms: 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-, sodium salt. CAS No. 55774-33-9. Product ID: API55774339. Molecular formula: C9H6N7NaO2S. Mole weight: 299.25. InChIKey: WISNYKIQFMKSDQ-UHFFFAOYSA-N. Appearance: Solid. | |
| Azetidine | Azetidine (also known as cyclobutane with one carbon replaced by nitrogen, or trimethyleneimine) is a four-membered saturated nitrogen-containing heterocycle. As a small, strained, and basic nitrogen heterocycle, it serves as both a pharmacophore and a building block in pharmaceutical synthesis. The ring strain (~26 kcal/mol) makes the ring susceptible to nucleophilic ring-opening reactions, while the nitrogen is readily alkylated and acylated. Applications: Azetidine is used as an intermediate in the synthesis of pharmaceuticals including the anti-parkinson agent budipine and other cns-active agents. it serves as a building block for the synthesis of azetidine-containing peptidomimetics, beta-amino acid derivatives, and constrained drug scaffolds. it is also used as a precursor for chiral auxiliaries, protecting groups, and in the synthesis of functional polymers. Category: Intermediates. Synonyms: 1,3-Propylenimine. CAS No. 503-29-7. Product ID: INT503297. Molecular formula: C3H7N. Mole weight: 57.09. EINECS: 207-963-8. InChIKey: HONIICLYMWZJFZ-UHFFFAOYSA-N. Appearance: Clear colorless liquid. | |
| Azithromycin | Azithromycin is a macrolide antibiotic useful for the treatment of bacterial infections. It has a role as an antibacterial drug, an environmental contaminant and a xenobiotic. Category: Antibacterial apis. Synonyms: Zithromax. Sumamed. Hemomycin. CAS No. 83905-01-5. Product ID: API83905015. Molecular formula: C38H72N2O12. Mole weight: 749. EINECS: 617-500-5. SMILES: CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O. Appearance: White Solid. | |
| Baicalin | Baicalin is a flavonoid glycoside isolated from Scutellaria baicalensis. Baicalin reduces the expression of NF-κB. Category: Active pharmaceutical ingredients. CAS No. 21967-41-9. Product ID: API21967419. Molecular formula: C21H18O11. Mole weight: 446.361. Appearance: Crystalline powder. | |
| Balofloxacin | Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase. Category: Active pharmaceutical ingredients. CAS No. 127294-70-6. Product ID: API127294706. Molecular formula: C20H24FN3O4. Mole weight: 389.42. | |
| Balofloxacin Dihydrate | Balofloxacin is a fluoroquinolone antibiotic with oral activity. Category: Active pharmaceutical ingredients. CAS No. 151060-21-8. Product ID: API151060218. Molecular formula: C20H28FN3O6. Mole weight: 425.45. | |
| Baloxavir | Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Category: Active pharmaceutical ingredients. CAS No. 1985605-59-1. Product ID: API1985605591. Molecular formula: C24H19F2N3O4S. Mole weight: 483.49. | |
| Baloxavir-d4 | Baloxavir-d4 is a deuterated compound of Baloxavir. Baloxavir has a CAS number of 1985605-59-1. Baloxavir is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Category: Active pharmaceutical ingredients. CAS No. 2415027-80-2. Product ID: API2415027802. Molecular formula: C24H15D4F2N3O4S. Mole weight: 487.51. | |
| Bambuterol Hydrochloride | Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. Category: Active pharmaceutical ingredients. CAS No. 81732-46-9. Product ID: API81732469. Molecular formula: C18H30ClN3O5. Mole weight: 403.901. Standard: EP/CP. | |
| Bamocaftor | Bamocaftor is a CFTR channel (DeltaF508-CFTR mutation) corrector for CF transmembrane conductance regulators designed to restore F508del-CFTR protein function. Combined use of tezacaftor and VX-561 for the treatment of cystic fibrosis patients with F508del/MF. Category: Active pharmaceutical ingredients. CAS No. 2204245-48-5. Product ID: API2204245485. Molecular formula: C28H32F3N5O4S. Mole weight: 591.65. | |
| BAY-751098 | BAY-751098 is a bio-active chemical. Category: Active pharmaceutical ingredients. CAS No. 1343498-72-5. Product ID: API1343498725. Molecular formula: C20H13ClF4N4O3. Mole weight: 468.79. | |
| BCAA | It is a monocarboxylic acid, an organochlorine compound and a 2-bromocarboxylic acid. Category: Amino acids and derivatives. Synonyms: Bromochloroacetic acid. 5589-96-8. 2-bromo-2-chloroacetic acid. Acetic acid, bromochloro-. Keratins. CAS No. 69430-36-0. Product ID: API69430360. Molecular formula: C2H2BrClO2. Mole weight: 173.39. EINECS: 627-754-9. SMILES: C(C(=O)O)(Cl)Br. Appearance: Crystalline compound. Standard: In-house. | |
| Beclomethasone Dipropionate | Beclomethasone Dipropionate is a synthetic glucocorticoid corticosteroid and the 17,21-dipropionate ester of beclomethasone. It is a prodrug that undergoes enzymatic hydrolysis to yield the active metabolite beclomethasone-17-monopropionate, a mechanism unique among commonly used corticosteroids. Applications: Indicated for the treatment of inflammatory skin conditions including eczema, dermatitis, and psoriasis. beclomethasone dipropionate is a prodrug corticosteroid that undergoes enzymatic hydrolysis to the active metabolite, providing potent topical anti-inflammatory activity with extended duration of action at the application site. Category: Active pharmaceutical ingredients. Synonyms: 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-pregna-1-4-diene-20-dione. CAS No. 5534-9-8. Product ID: API5534098. Molecular formula: C28H37ClO7. Mole weight: 521.04. EINECS: 226-886-0. InChIKey: KUVIULQEHSCUHY-XYWKZLDCSA-N. Appearance: White solid. | |
| Bedaquiline | Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Category: Antibacterial apis. Synonyms: TMC207. TMC-207. R207910. CAS No. 843663-66-1. Product ID: API843663661. Molecular formula: C32H31BrN2O2. Mole weight: 555.5. EINECS: 831-215-5. SMILES: CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O. Appearance: White solid. | |
| Bempedoic acid | Bempedoic acid is a synthetic small-molecule drug that acts as an inhibitor of ATP-citrate lyase (ACL), an enzyme in the hepatic cholesterol biosynthesis pathway upstream of HMG-CoA reductase (the target of statins). It is a prodrug activated by very long-chain acyl-CoA synthetase 1 (ACSVL1) in the liver, which converts it to the active-CoA thioester, ensuring liver-specific target engagement with minimal extrahepatic effects. Applications: Bempedoic acid is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease in adults who require additional ldl-cholesterol lowering. Category: Intermediates. CAS No. 738606-46-7. Product ID: INT738606467. Molecular formula: C19H36O5. Mole weight: 344.49. InChIKey: HYHMLYSLQUKXKP-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Benperidol | Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.Benperidol can be used in positron emission tomography (PET) scanning to measure D(2) dopamine receptor binding in vivo.Benperidol has been shown to be effective in blocking D2 receptors in vivo.Benperidol has been shown to be effective in blocking D2 receptors in vivo. Category: Active pharmaceutical ingredients. CAS No. 2062-84-2. Product ID: API2062842. Molecular formula: C22H24FN3O2. Mole weight: 381.44. | |
| Benperidol Hydrochloride | Benperidol Hydrochloride is a potent D2/D4 dopamine receptor antagonist, used as antipsychotic and neuroleptic. Category: Active pharmaceutical ingredients. CAS No. 74298-73-0. Product ID: API74298730. Molecular formula: C22H25ClFN3O2. Mole weight: 417.91. | |
| Bentiromide | Bentiromide is a synthetic peptide-like compound that serves as a non-invasive diagnostic agent for assessing pancreatic exocrine function. Its chemical structure incorporates a benzoyl group linked through a peptide bond to p-aminobenzoic acid (PABA), allowing it to function as a chymotrypsin substrate. Applications: Bentiromide is used as a diagnostic aid in the clinical assessment of exocrine pancreatic function. the procedure involves oral administration of bentiromide followed by timed urine collection to measure para-aminobenzoic acid (paba) recovery. reduced paba excretion indicates impaired pancreatic secretion and is suggestive of pancreatic exocrine insufficiency. Category: Active pharmaceutical ingredients. Synonyms: BZ-TYR-4-ABZ-OH;n-benzoyl-l-tyrosyl-p-aminobenzoicacid. CAS No. 37106-97-1. Product ID: API37106971. Molecular formula: C23H20N2O5. Mole weight: 404.4. EINECS: 253-349-8. InChIKey: SPPTWHFVYKCNNK-FQEVSTJZSA-N. Appearance: White to off-white solid. | |
| Bentracimab | Bentracimab is a monoclonal antibody that neutralizes Ticagrelor and its primary active metabolite by binding with high affinity, rapidly reversing Ticagrelor's antiplatelet effects. Category: Active pharmaceutical ingredients. CAS No. 2260568-31-6. Product ID: API2260568316. | |
| Benzalkonium Chloride | A synthetic quaternary ammonium salt used as a cationic surfactant and preservative in cosmetics and disinfectants. Category: Preservatives excipients. Synonyms: BENZALKONIUM CHLORIDE, BP 99+%;BenzalkoniumChlorideB.P.;BenzalkoniumChloridePure;BENZALKONIUM CHLORIDE SOLUTION 10%;BENZALKONIUM CHLORIDE SOLUTION 50%, PHARMA;BENZALKONIUM CHLORIDE, POWDER;BENZALKONIUM CHLORIDE, GEL;Benzalkonium chloride (non-medicinal). CAS No. 8001-54-5. Product ID: PIE-0080. Molecular formula: C17H30ClN. Mole weight: 283.88. Appearance: White or light yellow/grey Solid, or colourless aqueous solution. Standard: USP/ChP/NF/EP/JP. | |
| Benznidazole | Benznidazole is a nitroimidazole antimicrobial designated as an orphan drug by the FDA for the treatment of Chagas disease, an orphan disease in the United States. It is the first treatment made available in the U.S. for this condition and is indicated for pediatric patients ages 2 to 12 years. The drug is a member of the imidazoles and a C-nitro compound, functioning as an antiprotozoal agent. Applications: It is indicated for the treatment of chagas disease (american trypanosomiasis) caused by trypanosoma cruzi. in the u.s., it is approved for use in pediatric patients aged 2 to 12 years. the cdc also recommends antiparasitic treatment for all cases of acute or reactivated chagas disease and for chronic infection in children up to age 18; treatment is also recommended for infected adults 18 to 50 years old without advanced cardiomyopathy. Category: Active pharmaceutical ingredients. Synonyms: Benznidazol; Radanil; Benzonidazole; Rochagan; benzonidazol; Benznidazolum; N-benzyl-2-(2-nitroimidazol-1-yl)acetamide. CAS No. 22994-85-0. Product ID: API0231566. Molecular formula: C12H12N4O3. Mole weight: 260.25. EINECS: 624-902-4. InChIKey: CULUWZNBISUWAS-UHFFFAOYSA-N. Appearance: Off-white to light yellow powder. | |
| Benzoyl Peroxide | Benzoyl Peroxide is a potent keratolytic and antimicrobial agent widely used in the topical treatment of acne vulgaris. Its chemical structure consists of two benzoyl groups linked by a peroxide bridge, which decomposes on contact with skin to release reactive oxygen species and benzoic acid. This dual-action mechanism addresses both the inflammatory and microbiological components of acne. Applications: Benzoyl peroxide is indicated for the topical treatment of mild to moderate acne vulgaris, including comedonal, papulopustular, and mixed acne. it may be used as monotherapy or in combination with topical retinoids or antibiotics to enhance treatment efficacy and reduce bacterial resistance development. Category: Active pharmaceutical ingredients. CAS No. 94-36-0. Product ID: API94360. Molecular formula: C14H10O4. Mole weight: 242.23. EINECS: 202-327-6. InChIKey: OMPJBNCRMGITSC-UHFFFAOYSA-N. Appearance: White powder. | |
| Bepridil hydrochloride | Bepridil hydrochloride. Category: Active pharmaceutical ingredients. CAS No. 68099-86-5. Product ID: API68099865. Molecular formula: C24H35ClN2O. Mole weight: 403.001. | |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Category: Natural extract. Synonyms: TIMTEC-BB SBB006488;NATURAL YELLOW 18 CHLORIDE;NATURAL YELLOW 18;UMBELLATINE;BERBERINE HCL;BERBERINE HYDROCHLORIDE;BERBERIN HCL;BERBERINE HYDROCHLORIDE N-HYDRATE. CAS No. 633-65-8. Product ID: PIPE-0252. Molecular formula: C20H18ClNO4. Mole weight: 371.81. EINECS: 211-195-9. SMILES: C12C=C3C(C(OC)=C(OC)C=C3)=C[N+]=1CCC1=CC3=C(OCO3)C=C21.[Cl-]. InChIKey: VKJGBAJNNALVAV-UHFFFAOYSA-M. Appearance: Yellow Powder. Standard: CP. | |
| Berotralstat | Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein, which is responsible for the release of bradykinin. This blocking mechanism targets the major biologic peptide involved in the promotion of swelling and pain associated with HAE attacks. Category: Active pharmaceutical ingredients. CAS No. 1809010-50-1. Product ID: API1809010501. Molecular formula: C30H26F4N6O. Mole weight: 562.573. | |
| Berotralstat HCl | Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Category: Active pharmaceutical ingredients. CAS No. 1809010-52-3. Product ID: API1809010523. Molecular formula: C30H28Cl2F4N6O. Mole weight: 635.4886. | |
| Besifloxacin | Besifloxacin is the fourth generation of fluoroquinolones, which can be used to treat bacterial conjunctivitis. Category: Active pharmaceutical ingredients. CAS No. 141388-76-3. Product ID: API141388763. Molecular formula: C19H21ClFN3O3. Mole weight: 393.84. | |
| Besifloxacin Hydrochloride | Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic. Category: Active pharmaceutical ingredients. Synonyms: BOL-303224-A, Besivance hydrochloride, Besifloxacin HCl. CAS No. 405165-61-9. Product ID: API405165619. Molecular formula: C19H21ClFN3O3·HCl. Mole weight: 430.3. | |
| β-Glucuronidase | Beta-glucuronidase is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan. Category: Active pharmaceutical ingredients. CAS No. 9001-45-0. Product ID: API9001450. | |
| Betahistine Hydrochloride | A histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Category: Cardiovascular and geriatric medicine apis. Synonyms: N-Methyl-2-(pyridin-2-yl)ethanamine hydrochloride. Serc. Pyridine, 2-(2-(methylamino)ethyl)-, hydrochloride. CAS No. 15430-48-5. Product ID: API15430485. Molecular formula: C8H13ClN2. Mole weight: 172.65. SMILES: CNCCC1=CC=CC=N1.Cl. Appearance: White Solid. | |
| Betaine | Betaine (trimethylglycine) is an orally administered agent used to reduce homocysteine levels in patients with homocystinuria. It is a naturally occurring derivative of the amino acid glycine and functions as a methyl donor. Applications: Betaine is indicated for the treatment of homocystinuria to lower dangerously elevated homocysteine levels, thereby decreasing the risk of thromboembolism, lens dislocation, skeletal abnormalities, and developmental delay. it is used as an adjunct to dietary protein restriction and vitamin b6/b12 therapy. dosing is individualized based on homocysteine response, and monitoring includes plasma methionine levels to avoid toxicity. Category: Veterinary products. Synonyms: glycine betaine; oxyneurine; Trimethylglycine; lycine; Abromine; Trimethylglycocoll; Glycocoll betaine. CAS No. 107-43-7. Product ID: PIVF-0058. Molecular formula: C5H11NO2. Mole weight: 117.15. EINECS: 203-490-6. InChIKey: KWIUHFFTVRNATP-UHFFFAOYSA-N. Appearance: White crystalline powder. | |
| Betamethasone 17-Propionate | Betamethasone 17-Propionate is a compound used in the study of its effects on endotoxin-induced uveitis in rats, capable of inhibiting cellular infiltration into the aqueous humor when administered topically or systemically at certain doses. Category: Active pharmaceutical ingredients. CAS No. 5534-13-4. Product ID: API5534134. Molecular formula: C25H33FO6. Mole weight: 448.52. | |
| Betamethasone 21-valerate | Betamethasone 21-valerate is a corticosteroid ester with anti-inflammatory properties. Category: Active pharmaceutical ingredients. CAS No. 2240-28-0. Product ID: API2240280. Molecular formula: C27H37FO6. Mole weight: 476.58. | |
| Betamethasone Benzoate | Betamethasone Benzoate is a synthetic corticosteroid ester combining betamethasone with benzoic acid, designed for enhanced topical bioavailability and penetration into the skin. The benzoate ester increases lipophilicity compared to the base betamethasone molecule, facilitating more efficient delivery across the stratum corneum. It is classified as a high-potency topical corticosteroid. Applications: Betamethasone benzoate is indicated for the topical treatment of corticosteroid-responsive dermatoses including atopic dermatitis, contact dermatitis, psoriasis, seborrheic dermatitis, and lichen planus where high-potency anti-inflammatory action is required. Category: Active pharmaceutical ingredients. CAS No. 22298-29-9. Product ID: API22298299. Molecular formula: C29H33FO6. Mole weight: 496.6. InChIKey: SOQJPQZCPBDOMF-YCUXZELOSA-N. Appearance: Powder. | |
| Betamethasone Dipropionate | Betamethasone Dipropionate is a synthetic fluorinated corticosteroid with a double ester (dipropionate) substitution, conferring very high topical potency and enhanced lipophilicity compared to betamethasone base or its monopropionate salt. The dipropionate ester significantly increases the drug's affinity for the glucocorticoid receptor in skin tissue and prolongs its residence time at the site of application. Applications: Betamethasone dipropionate is indicated for the topical treatment of severe inflammatory and pruritic dermatoses that are unresponsive to lower-potency corticosteroids, including severe atopic dermatitis, generalized erythrodermic psoriasis, severe allergic contact dermatitis, and autoimmune blistering disorders. Category: Active pharmaceutical ingredients. Synonyms: Betamethasone 17,21-dipropionate;9-Fluoro-16-methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate. CAS No. 5593-20-4. Product ID: API5593204. Molecular formula: C28H37FO7. Mole weight: 504.6. EINECS: 227-005-2. InChIKey: CIWBQSYVNNPZIQ-XYWKZLDCSA-N. Appearance: White to pale yellow powder. | |
| Betamethasone disodium phosphate | Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory properties that promotes the polarization of M1 to M2 macrophages by reducing the secretion of pro-inflammatory cytokines, and is utilized in research on keloids and rheumatoid arthritis. Category: Active pharmaceutical ingredients. CAS No. 151-73-5. Product ID: API151735. Molecular formula: C22H28FNa2O8P. Mole weight: 516.41. | |
| Betamethasone valerate | Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Category: Active pharmaceutical ingredients. CAS No. 2152-44-5. Product ID: API2152445. Molecular formula: C27H37FO6. Mole weight: 476.58. | |
| beta-Methyl vinyl phosphate (MAP) | beta-Methyl vinyl phosphate (MAP) is a critical phosphate ester compound and a high-value pharmaceutical intermediate. This advanced intermediate is structurally essential for the synthesis of antibiotics in the Penem (Carbapenem) class, serving as a key precursor in the manufacturing process. Applications: Map is a fundamental pharmaceutical intermediate for the preparation of advanced antibiotics, notably the penem drugs, thereby supporting the production of next-generation antibacterial agents. additionally, as a phosphate ester, it is broadly employed in chemical and biological research where it serves as a critical substrate for phosphorylation reactions necessary for investigating and understanding essential protein functions and cellular signaling pathways. Category: Intermediates. Synonyms: (4R,5R,6S)-3-[(Diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (4-Nitrophenyl)methyl Ester. CAS No. 90776-59-3. Product ID: INT90776593. Molecular formula: C29H27N2O10P. Mole weight: 594.51. EINECS: 618-646-2. InChIKey: STULDTCHQXVRIX-PIYXRGFCSA-N. Appearance: White solid. | |
| β-Nicotinamide Mononucleotide | β-Nicotinamide Mononucleotide. Category: Hypoglycemic apis. Synonyms: BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium;B-NICOTINAMIDE MONONUCLEOTIDE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE;NICOTINAMIDE RIBOTIDE. CAS No. 1094-61-7. Product ID: API1094617. Molecular formula: C11H15N2O8P. Mole weight: 334.22. EINECS: 214-136-5. SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)([O-])=O)O[C@H]1[N+]1=CC=CC(C(=O)N)=C1)O |&1:1,2,3,11,r|. InChIKey: DAYLJWODMCOQEW-TURQNECASA-N. Appearance: Solid. | |
| Betrixaban | Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients. Category: Active pharmaceutical ingredients. Synonyms: PRT054021. Bevyxxa. N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide. CAS No. 330942-05-7. Product ID: API330942057. Molecular formula: C23H22ClN5O3. Mole weight: 451.9. EINECS: 682-459-2. SMILES: CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl. | |
| Bezafibrate | Bezafibrate is a peroxisome proliferator and hypolipidaemic agent. Category: Active pharmaceutical ingredients. CAS No. 41859-67-0. Product ID: API41859670. Molecular formula: C19H20ClNO4. Mole weight: 361.82. | |
| Bicalutamide | Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. Category: Active pharmaceutical ingredients. CAS No. 90357-06-5. Product ID: API90357065. Molecular formula: C18H14F4N2O4S. Mole weight: 430.37. | |
| BictegravirGS-9883 | Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 value of 7.5 nM. Category: Active pharmaceutical ingredients. CAS No. 1611493-60-7. Product ID: API1611493607. Molecular formula: C21H18F3N3O5. Mole weight: 449.38. | |
| Bictegravir Sodium | Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity. Category: Active pharmaceutical ingredients. CAS No. 1807988-02-8. Product ID: API1807988028. Molecular formula: C21H17F3N3NaO5. Mole weight: 471.36. | |
| Bifendatatum | Bifendatatum inhibits alanine aminotransferase, which is used in the treatment of chronic persistent hepatitis, chronic active hepatitis and other diseases. Category: Active pharmaceutical ingredients. CAS No. 73536-69-3. Product ID: API73536693. Molecular formula: C20H18O10. Mole weight: 418.35. Standard: CP. | |
| Binimetinib | Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation. Category: Active pharmaceutical ingredients. CAS No. 606143-89-9. Product ID: API606143899. Molecular formula: C17H15BrF2N4O3. Mole weight: 441.23. | |
| Bisabolol | Bisabolol is a botanical used for its anti-inflammatory and soothing properties. It is derived from chamomile and/or yarrow. Category: Natural extract. Synonyms: α-bisabolol,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol,dragosantol;3-Cyclohexene-1-methanol. alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel-;6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepteno;alpha-Bisabalol. CAS No. 515-69-5. Product ID: PIPE-0062. Molecular formula: C15H26O. Mole weight: 222.37. EINECS: 208-205-9. Appearance: Liquid. Standard: In house. | |
| Bisbentiamine | Bisbentiamine is a vitamin B1 disulfide derivative that has been shown to have high bioavailability invitro. It is easily digested by cells into vitamin B1. Category: Active pharmaceutical ingredients. CAS No. 2667-89-2. Product ID: API2667892. Molecular formula: C38H42N8O6S2. Mole weight: 770.92. Appearance: Crystalline powder. | |
| Bismuth Potassium Citrate | Gastrodenol is a mineral that is used in treating ulcers and upset stomach. Category: Other apis. Synonyms: bismuth;potassium;2-hydroxypropane-1,2,3-tricarboxylate. BISMUTHPOTASSIUMCITRATE. A831537. CAS No. 57644-54-9. Product ID: API57644549. Molecular formula: C6H5BiKO7+. Mole weight: 437.18. EINECS: 260-872-5. SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[K+].[Bi+3]. | |
| Bisoprolol fumarate | Bisoprolol is a selective type β1 adrenergic receptor blocker. Category: Active pharmaceutical ingredients. CAS No. 104344-23-2. Product ID: API104344232. Molecular formula: C40H66N2O12. Mole weight: 766.96. Appearance: White solid. | |
| Bitolterol Mesylate | Bitolterol Mesylate is a synthetic catecholamine prodrug and long-acting beta-2 adrenergic agonist (LABA) developed for the bronchodilator treatment of asthma and chronic obstructive pulmonary disease (COPD). Its unique double-ester prodrug structure (ditolylmethyl ester) provides a prolonged duration of bronchodilation through slow hydrolysis to the active metabolite colterol at the site of action. Applications: Bitolterol mesylate is indicated as a bronchodilator for the prophylaxis and treatment of asthma, bronchospasm in copd, and reversible airway obstruction. Category: Active pharmaceutical ingredients. Synonyms: [4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(4-methylbenzoyl)oxyphenyl] 4-methylbenzoate;methanesulfonic acid. CAS No. 30392-41-7. Product ID: API30392417. Molecular formula: C29H35NO8S. Mole weight: 557.7. InChIKey: HODFCFXCOMKRCG-UHFFFAOYSA-N. | |
| Bivalirudin TFA | Bivalirudin TFA, a synthetic 20-residue peptide, serves as a reversible inhibitor of thrombin. Its IC50 value highlights its target specificity in vitro, where, combined with Eptifibatide (8 mg/mL) at a low concentration (70 ng/mL), it significantly reduces platelet aggregation induced by thrombin (0.2 U/mL) by approximately 90%. Category: Active pharmaceutical ingredients. CAS No. 1191386-55-6. Product ID: API1191386556. Molecular formula: C98H138N24O33.C2HF3O2. Mole weight: 2294.34. | |
| Blonanserin-d5 | Blonanserin-d5 is a deuterated compound of Blonanserin. Blonanserin has a CAS number of 132810-10-7. Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal symptoms, excessive sedation, or hypotension. Category: Active pharmaceutical ingredients. CAS No. 1346599-86-7. Product ID: API1346599867. Molecular formula: C23H25D5FN3. Mole weight: 372.53. | |
| Blonanserin HCl | Blonanserin is an antagonist of dopamine-D2 and serotonin-S2. Category: Active pharmaceutical ingredients. Synonyms: Blonanserin dihydrochloride, AD 5423. CAS No. 132812-45-4. Product ID: API132812454. Molecular formula: C23H32Cl2FN3. Mole weight: 440.42. | |
| Borax | Sodium tetraborate decahydrate is used as an anti-fungal agent in pharmaceutical formulations. Category: Preservatives excipients. Synonyms: Borax (B4Na2O7.10H2O). Borax decahydrate. SODIUM BORATE, DECAHYDRATE. CAS No. 1303-96-4. Product ID: PIE-0311. Molecular formula: B4O7Na2. 10H2O. Mole weight: 381.4. EINECS: 603-411-9. SMILES: B1(OB2OB(OB(O1)O2)[O-])[O-].O.O.O.O.O.O.O.O.O.O.[Na+].[Na+]. Appearance: Dry Powder. | |
| Bretylium Tosylate | Bretylium tosylate is a class III antiarrhythmic agent that also exhibits class II (antiadrenergic) properties, used primarily in emergency settings for the treatment of life-threatening ventricular arrhythmias. It is administered intravenously or intramuscularly and acts by suppressing ventricular fibrillation and ventricular tachycardia. The drug is a quaternary ammonium compound that accumulates in sympathetic ganglia and nerve terminals. Applications: It is indicated for the treatment of ventricular fibrillation and hemodynamically unstable ventricular tachycardia that is unresponsive to other antiarrhythmics, particularly in the setting of acute myocardial infarction. however, its use has declined significantly due to the availability of more effective and safer agents such as amiodarone. it remains available as a second-line agent in advanced cardiac life support protocols. Category: Antiarrhythmic apis. Synonyms: Bretylol; Bretylium tosilate; Darentin; Tosilato de bretilio; Tosilate de bretylium; Bretylii tosilas; ASL-603; Bretilio tosilato. CAS No. 61-75-6. Product ID: API0231559. Molecular formula: C18H24BrNO3S. Mole weight: 414.4. EINECS: 200-516-8. InChIKey: KVWNWTZZBKCOPM-UHFFFAOYSA-M. Appearance: White to off-white crystalline powder. | |
| Brimonidine | Brimonidine is a full α2-adrenergic receptor (α2-AR) agonist. Category: Active pharmaceutical ingredients. CAS No. 59803-98-4. Product ID: API59803984. Molecular formula: C11H10BrN5. Mole weight: 292.14. | |
| Brimonidine Tartrate | Brimonidine Tartrate is a highly selective alpha-2 adrenergic receptor agonist (alpha-2A predominant) used topically to reduce elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. The tartrate salt optimizes solubility and ocular bioavailability. Compared to apraclonidine, brimonidine exhibits greater alpha-2 receptor selectivity and has a broader safety profile due to its lower propensity for allergic reactions. Applications: Brimonidine tartrate is indicated as first-line or adjunctive monotherapy for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. its favorable tolerability profile and added neuroprotective potential make it a preferred choice in many clinical scenarios. Category: Active pharmaceutical ingredients. Synonyms: 5-BROMO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-QUINOXALINAMINE TARTRATE;5-BROMO-6-(2-IMIDAZOLIN-2-YLAMINO)QUINOXALINE TARTRATE. CAS No. 70359-46-5. Product ID: API70359465. Molecular formula: C15H16BrN5O6. Mole weight: 442.22. EINECS: 629-848-5. InChIKey: QZHBYNSSDLTCRG-LREBCSMRSA-N. Appearance: White to off-white solid. | |
| Bromelain | Bromelain is a highly purified, natural plant protease complex obtained from pineapples (fruit, skin, and core). It is a light yellow-brown powder with a pineapple odor and can be used in food, pharmaceutical and biological applications. Applications: In pharmaceutical applications, bromelain is used in acute and chronic inflammation, respiratory ailments, and trauma (post-surgery) for its wound-healing and bone-healing actions. in the food industry, it is mainly used for tenderization of meat, cold-stabilization of beer, and the manufacture of high-quality hydrolyzed protein. Category: Natural extract. CAS No. 9001-00-7. Product ID: PIPE-0064. EINECS: 232-572-4. Appearance: Yellow-brown powder. | |
| Bromocriptine Mesylate | Bromocriptine Mesylate is the mesylate salt of bromocriptine, a semisynthetic ergot alkaloid derivative with potent dopamine D2 receptor agonist activity. It is derived from ergocryptine and possesses a complex pharmacological profile affecting multiple neurotransmitter systems. Applications: Indicated for the treatment of parkinson's disease, hyperprolactinemia, and acromegaly. bromocriptine mesylate is a dopamine d2 receptor agonist and ergot alkaloid derivative that effectively suppresses prolactin secretion and improves motor function in parkinsonian patients through dopaminergic pathway modulation. Category: Active pharmaceutical ingredients. Synonyms: Bromocriptine mesilate. CAS No. 22260-51-1. Product ID: API22260511. Molecular formula: C33H44BrN5O8S. Mole weight: 750.7. EINECS: 244-881-1. InChIKey: NOJMTMIRQRDZMT-GSPXQYRGSA-N. Appearance: White solid. | |
| Bromperidol | Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 10457-90-6. Product ID: API10457906. Molecular formula: C21H23BrFNO2. Mole weight: 420.32. | |
| Bromperidol decanoate | Bromperidol decanoate is an antipsychotic agent that is utilized for long-term maintenance treatment for schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 75067-66-2. Product ID: API75067662. Molecular formula: C31H41BrFNO3. Mole weight: 574.56. | |
| Bromperidol hydrochloride | Bromperidol hydrochloride (R-11333 hydrochloride) is an antipsychotic agent with good affinity for the central dopamine receptors D2. Spectinomycin synergistically kills mycobacteria. Category: Active pharmaceutical ingredients. CAS No. 59453-24-6. Product ID: API59453246. Molecular formula: C21H24BrClFNO2. Mole weight: 456.78. | |
| Bronchospasmolytic agent 1 | Bronchospasmolytic agent 1 is a flutropium bromide compound and acts as a bronchospasmolytic agent. Category: Active pharmaceutical ingredients. CAS No. 63516-10-9. Product ID: API63516109. Molecular formula: C24H29BrFNO3. Mole weight: 478.39. | |
| Bumetanide | Bumetanide is a derivative of aminobenzenesulfonamide and belongs to the class of "loop diuretics." It is typically more potent than furosemide, but its duration of action is relatively shorter. It is usually administered in the form of oral tablets or injectable solutions. The injectable form works more quickly and is listed as a drug in shortage by the FDA. Applications: It is used to treat edema associated with heart failure, liver disease, and kidney disease. it is mainly indicated for various refractory edemas and acute pulmonary edema, and is particularly suitable for patients with acute and chronic renal failure. Category: Diuretic apis. Synonyms: 3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid; Bumex; Burinex. CAS No. 28395-03-1. Product ID: API28395031. Molecular formula: C17H20N2O5S. Mole weight: 364.4. EINECS: 249-004-6. InChIKey: MAEIEVLCKWDQJH-UHFFFAOYSA-N. Appearance: White to light yellow solid. | |
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