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Flibanserin hydrochloride
Flibanserin (BIMT-17; BIMT-17BS) hydrochloride is an orally active compound that functions as a 5-HT1A receptor agonist (Ki: 1 nM) and a 5-HT2A receptor antagonist (Ki: 49 nM) of 5-hydroxytryptamine. It possesses antidepressant and anxiolytic effects and is used in studies of hypoactive sexual desire (HSDD). Category: Active pharmaceutical ingredients. CAS No. 147359-76-0. Product ID: API147359760. Molecular formula: C20H22ClF3N4O. Mole weight: 426.87.
Flobetapir
Flobetapir (AV-45) is a well-tolerated imaging compound used in PET scanning. It is synthesized to create Florbetapir (18F), which is a radiopharmaceutical compound containing fluorine-18 radionuclide. Category: Active pharmaceutical ingredients. CAS No. 938435-69-9. Product ID: API938435699. Molecular formula: C20H25FN2O3. Mole weight: 360.429.
Floctafenine
Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet effects of aspirin.Floctafenine has analgesic activity and is used in the study of pain. Category: Active pharmaceutical ingredients. CAS No. 23779-99-9. Product ID: API23779999. Molecular formula: C20H17F3N2O4. Mole weight: 406.36.
Flomoxef
Flomoxef is an antibiotic in oxacephem group and has excellent activity against various gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 99665-00-6. Product ID: API99665006. Molecular formula: C15H18F2N6O7S2. Mole weight: 496.47.
Flomoxef sodium
Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 92823-03-5. Product ID: API92823035. Molecular formula: C15H17F2N6NaO7S2. Mole weight: 518.44.
Florilglutamic acid (18F)
Florilglutamic acid (18F) is a bioactive chemical. Category: Active pharmaceutical ingredients. CAS No. 1196963-74-2. Product ID: API1196963742. Molecular formula: C8H14FNO4. Mole weight: 206.2.
Flosequinan
Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure. Category: Active pharmaceutical ingredients. CAS No. 76568-02-0. Product ID: API76568020. Molecular formula: C11H10FNO2S. Mole weight: 239.27.
Floxuridine
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. Category: Active pharmaceutical ingredients. CAS No. 50-91-9. Product ID: API50919. Molecular formula: C9H11FN2O5. Mole weight: 246.19.
Fluanisone
Fluanisone (Haloanison) is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 1480-19-9. Product ID: API1480199. Molecular formula: C21H25FN2O2. Mole weight: 356.43.
Fluazacort
Fluazacort is an anti-inflammatory agent. Category: Active pharmaceutical ingredients. CAS No. 19888-56-3. Product ID: API19888563. Molecular formula: C25H30FNO6. Mole weight: 459.51.
Flucloronide
Flucloronide is a corticosteroid for topical use on the skin. It has anti-inflammatory properties. Category: Active pharmaceutical ingredients. Synonyms: RS 2252. CAS No. 3693-39-8. Product ID: API3693398. Molecular formula: C24H29Cl2FO5. Mole weight: 487.39.
Flucloxacillin
Flucloxacillin, an antibiotic, effectively combats both gram-positive and gram-negative bacteria. Category: Active pharmaceutical ingredients. CAS No. 5250-39-5. Product ID: API5250395. Molecular formula: C19H17ClFN3O5S. Mole weight: 453.87.
Flucloxacillin sodiumfloxacillin sodium
Flucloxacillin sodium (floxacillin sodium) is a highly active antibiotic against Gram-negative and Gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 1847-24-1. Product ID: API1847241. Molecular formula: C19H16ClFN3NaO5S. Mole weight: 475.85.
Fludarabine Phosphate
Fludarabine phosphate is a purine nucleoside analogue with potent antineoplastic and immunosuppressive activity, used primarily in the treatment of hematologic malignancies. It is administered intravenously or orally and is a prodrug that is rapidly dephosphorylated to fludarabine, then intracellularly converted to its active triphosphate form. The drug is a cornerstone of therapy for chronic lymphocytic leukemia. Applications: It is indicated for the treatment of b-cell chronic lymphocytic leukemia (cll) in patients who have not responded to or have progressed after first-line alkylator-based therapy. it is also used in combination regimens for non-hodgkin lymphoma and acute myeloid leukemia. in allogeneic stem cell transplantation, it serves as part of reduced-intensity conditioning protocols due to its potent immunosuppressive properties. myelosuppression, immunosuppression with opportunistic infections, and dose-related neurotoxicity are significant adverse effects. Category: Fluorine-containing apis. Synonyms: Fludarabine 5'-monophosphate; Oforta; Fludarabine monophosphate; 2-F-ara-AMP; NSC-312887; 2-Fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine; 1X9VK9O1SC. CAS No. 75607-67-9. Product ID: API75607679. Molecular formula: C10H13FN5O7P. Mole weight: 365.21. EINECS: 616-242-0. InChIKey: GIUYCYHIANZCFB-FJFJXFQQSA-N. Appearance: White to light yellow crystalline powder.
Fludarabine triphosphate
Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate, inhibits ribonucleotide reductase and DNA polymerase, ultimately leading to cellular apoptosis. Category: Active pharmaceutical ingredients. Synonyms: F-ara-ATP. CAS No. 74832-57-8. Product ID: API74832578. Molecular formula: C10H15FN5O13P3. Mole weight: 525.172.
Fludrocortisone
Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency. Fludrocortisone is in research use for the treatment of hypotension.[3]. Category: Active pharmaceutical ingredients. CAS No. 127-31-1. Product ID: API127311. Molecular formula: C21H29FO5. Mole weight: 380.45.
Fludrocortisone acetate
Fludrocortisone acetate (9α-Fludrocortisone acetate), a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and initiates transcription of glucocorticoid-responsive genes like lipocortins to inhibit phospholipase A2 (PLA2). Category: Active pharmaceutical ingredients. CAS No. 514-36-3. Product ID: API514363. Molecular formula: C23H31FO6. Mole weight: 422.49.
Flufenamic acid
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. Category: Active pharmaceutical ingredients. CAS No. 530-78-9. Product ID: API530789. Molecular formula: C14H10F3NO2. Mole weight: 281.23.
Flufenamic Acid-d4
Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 μM for human COX-1 and COX-2, respectively). Category: Active pharmaceutical ingredients. CAS No. 1185071-99-1. Product ID: API1185071991. Molecular formula: C14H6D4F3NO2. Mole weight: 285.26.
Flumatinib
Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor with potential antineoplastic activity. Category: Active pharmaceutical ingredients. CAS No. 895519-90-1. Product ID: API895519901. Molecular formula: C29H29F3N8O. Mole weight: 562.59.
Flumatinib mesylate
Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants. Category: Active pharmaceutical ingredients. Synonyms: HHGV678 mesylate. CAS No. 895519-91-2. Product ID: API895519912. Molecular formula: C30H33F3N8O4S. Mole weight: 658.69.
Flumazenil
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. Category: Active pharmaceutical ingredients. Synonyms: Ro 15-1788. CAS No. 78755-81-4. Product ID: API78755814. Molecular formula: C15H14FN3O3. Mole weight: 303.29.
Flumazenil acidRo 15-3890
Flumazenil is an antagonist of GABAA receptor. Flumazenil acid is a metabolite of Flumazenil. Category: Active pharmaceutical ingredients. CAS No. 84378-44-9. Product ID: API84378449. Molecular formula: C13H10FN3O3. Mole weight: 275.24.
Flumedroxone acetate
Flumedroxone acetate is a progestogen medication which is or has been used as an antimigraine. Category: Active pharmaceutical ingredients. CAS No. 987-18-8. Product ID: API987188. Molecular formula: C24H31F3O4. Mole weight: 440.5.
Flumethasone 21-acetate
Flumethasone 21-acetate is an anti-inflammatory corticosteroid. Category: Active pharmaceutical ingredients. CAS No. 2823-42-9. Product ID: API2823429. Molecular formula: C24H30F2O6. Mole weight: 452.49.
Flumethasone pivalate
Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telangiectasia. Category: Active pharmaceutical ingredients. Synonyms: NSC-107680. CAS No. 2002-29-1. Product ID: API2002291. Molecular formula: C27H36F2O6. Mole weight: 494.57.
Flunarizine dihydrochloride
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. Category: Active pharmaceutical ingredients. CAS No. 30484-77-6. Product ID: API30484776. Molecular formula: C26H28Cl2F2N2. Mole weight: 477.42.
FlunarizineSibelium
Flunarizine is a non-selective calcium entry blocker and a histamine H1 receptor blocker. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of. Category: Active pharmaceutical ingredients. CAS No. 52468-60-7. Product ID: API52468607. Molecular formula: C15H14FN3O3. Mole weight: 303.29.
Flunisolide hemihydrate
Flunisolide hemihydrate is a corticosteroid, an orally active Glucocorticoid receptor activator with anti-inflammatory effects. flunisolide hemihydrate induces apoptosis in eosinophils and can be used in asthma or rhinitis, inflammatory diseases. Can be used in studies related to asthma or rhinitis, inflammation. Category: Active pharmaceutical ingredients. CAS No. 77326-96-6. Product ID: API77326966. Molecular formula: C48H64F2O13. Mole weight: 887.024.
Flunixin Meglumine
Flunixin Meglumine is a potent cyclooxygenase inhibitor used as a analgesic with anti-inflammatory and antipyretic activity. Category: Active pharmaceutical ingredients. CAS No. 42461-84-7. Product ID: API42461847. Molecular formula: C21H28F3N3O7. Mole weight: 491.46. Appearance: Solid. Standard: USP/EP.
Fluocinolone
Fluocinolone, a corticosteroid, is used to alleviate redness, itching, swelling, and other discomforts caused by skin conditions. Category: Active pharmaceutical ingredients. CAS No. 807-38-5. Product ID: API807385. Molecular formula: C21H26F2O6. Mole weight: 412.42.
Fluocinolone (Acetonide)
Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. Category: Active pharmaceutical ingredients. CAS No. 67-73-2. Product ID: API67732. Molecular formula: C24H30F2O6. Mole weight: 452.49.
Fluocortin butyl ester
Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when used topically. It appears to be an effective, well-tolerated topical steroid suitable for studies of perennial rhinitis. Category: Active pharmaceutical ingredients. CAS No. 41767-29-7. Product ID: API41767297. Molecular formula: C26H35FO5. Mole weight: 446.55.
Fluorometholone
Fluorometholone is a synthetic fluorinated glucocorticoid developed specifically for ophthalmic applications. It features a 9-fluoro and 6-methyl substitution on the pregnane steroid skeleton, which together provide potent anti-inflammatory activity with a pharmacokinetic profile that reduces intraocular pressure elevation compared to prednisolone. Applications: Indicated for the treatment of ocular inflammation including postoperative inflammation, anterior uveitis, and allergic conjunctivitis. fluorometholone is a synthetic fluorinated glucocorticoid designed specifically for ophthalmic use, providing potent anti-inflammatory activity with reduced risk of intraocular pressure elevation. Category: Active pharmaceutical ingredients. Synonyms: (6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;2Chemicalbook1-Desoxy-9a-fluoro-6-methylprednisolone;6a-Methyl-9a-fluoro-21-desoxyprednisolone;9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione. CAS No. 426-13-1. Product ID: API426131. Molecular formula: C22H29FO4. Mole weight: 376.5. EINECS: 207-041-5. InChIKey: FAOZLTXFLGPHNG-KNAQIMQKSA-N. Appearance: White to off-white solid.
Fluoxetine
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity. Category: Active pharmaceutical ingredients. CAS No. 54910-89-3. Product ID: API54910893. Molecular formula: C17H18F3NO. Mole weight: 309.33.
(±)-Fluoxetine-d4 Oxalate
(±)-Fluoxetine-d4 Oxalate is a deuterated compound of (±)-Fluoxetine Oxalate. (±)-Fluoxetine Oxalate has a CAS number of 114414-02-7. Category: Active pharmaceutical ingredients. CAS No. 2708283-92-3. Product ID: API2708283923. Molecular formula: C19H16D4F3NO5. Mole weight: 403.39.
Fluoxetine hydrochloride
Fluoxetine hydrochloride is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants. Category: Active pharmaceutical ingredients. CAS No. 56296-78-7. Product ID: API56296787. Molecular formula: C17H19ClF3NO. Mole weight: 345.787.
Fluoxetine oxalate
Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Category: Active pharmaceutical ingredients. CAS No. 114414-02-7. Product ID: API114414027. Molecular formula: C19H20F3NO5. Mole weight: 399.36.
Fluoxetine succinate ester
Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive-compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Category: Active pharmaceutical ingredients. CAS No. 1026723-45-4. Product ID: API1026723454. Molecular formula: C21H22F3NO4. Mole weight: 409.4.
Flupenthixol
Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant. Category: Active pharmaceutical ingredients. CAS No. 2709-56-0. Product ID: API2709560. Molecular formula: C23H25F3N2OS. Mole weight: 434.52.
Flupentixol decanoate, (Z)-
Flupentixol decanoate, (Z)- is an Dopamine Antagonists. Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Category: Active pharmaceutical ingredients. CAS No. 69079-98-7. Product ID: API69079987. Molecular formula: C33H43F3N2O2S. Mole weight: 588.77.
Flupentixol dihydrochloride
Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders. Category: Active pharmaceutical ingredients. CAS No. 2413-38-9. Product ID: API2413389. Molecular formula: C23H27Cl2F3N2OS. Mole weight: 507.43.
Fluperolone acetate
Fluperolone acetate is a Glucocorticoid/Adrenal Cortex Hormone. Category: Active pharmaceutical ingredients. CAS No. 2119-75-7. Product ID: API2119757. Molecular formula: C24H31FO6. Mole weight: 434.5.
Fluphenazine decanoate
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 5002-47-1. Product ID: API5002471. Molecular formula: C32H44F3N3O2S. Mole weight: 591.77.
Fluphenazine Decanoate Dihydrochloride
Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, it could block postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. Category: Active pharmaceutical ingredients. CAS No. 2376-65-0. Product ID: API2376650. Molecular formula: C32H46Cl2F3N3O2S. Mole weight: 664.69.
Fluphenazine dihydrochloride
Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist. Category: Active pharmaceutical ingredients. CAS No. 146-56-5. Product ID: API146565. Molecular formula: C22H28Cl2F3N3OS. Mole weight: 510.44.
Fluphenazine enanthate
Fluphenazine enanthate is a novel long-acting injectable (LAI) antipsychotic compound specifically designed for the treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 2746-81-8. Product ID: API2746818. Molecular formula: C29H38F3N3O2S. Mole weight: 549.69.
Fluphenazine free base
Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine works by blocking postsynaptic dopamine D2 receptors in the limbic system, cortical system, and basal ganglia. This prevents the effects. Category: Active pharmaceutical ingredients. CAS No. 69-23-8. Product ID: API69238. Molecular formula: C22H26F3N3OS. Mole weight: 437.52.
(+)-Fluprostenol
(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1). Category: Active pharmaceutical ingredients. CAS No. 54276-17-4. Product ID: API54276174. Molecular formula: C23H29F3O6. Mole weight: 458.47.
Fluprostenol methyl ester
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. CAY10532 is a methyl ester analog of fluprostenol. Category: Active pharmaceutical ingredients. CAS No. 73275-76-0. Product ID: API73275760. Molecular formula: C24H31F3O6. Mole weight: 472.49.
Flurandrenolide
Fludroxycortide, a synthetic topical steroid, serves as an anti-inflammatory treatment for skin irritations. Category: Active pharmaceutical ingredients. CAS No. 1524-88-5. Product ID: API1524885. Molecular formula: C24H33FO6. Mole weight: 436.51.
Flurbiprofen Axetil
Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic. Category: Active pharmaceutical ingredients. CAS No. 91503-79-6. Product ID: API91503796. Molecular formula: C19H19FO4. Mole weight: 330.35.
Flurbiprofen sodium
Flurbiprofen sodium is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase. Category: Active pharmaceutical ingredients. CAS No. 56767-76-1. Product ID: API56767761. Molecular formula: C15H12FNaO2. Mole weight: 266.24.
Fluspiperone
Fluspiperone is an antipsychotic agent. Category: Active pharmaceutical ingredients. CAS No. 54965-22-9. Product ID: API54965229. Molecular formula: C23H25F2N3O2. Mole weight: 413.46.
Fluspirilene
Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 1841-19-6. Product ID: API1841196. Molecular formula: C29H31F2N3O. Mole weight: 475.57.
Flutamide
Flutamide (SCH 13521) is an antiandrogen with about the same potency as cyproterone in rodent and canine species. Category: Active pharmaceutical ingredients. CAS No. 13311-84-7. Product ID: API13311847. Molecular formula: C11H11F3N2O3. Mole weight: 276.21.
Flutamide-d7
Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonistand prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. Category: Active pharmaceutical ingredients. CAS No. 223134-72-3. Product ID: API223134723. Molecular formula: C11H4D7F3N2O3. Mole weight: 283.26.
FlutaMide Related CoMpound B
FlutaMide Related CoMpound B is used as pharmaceutical intermediates. Category: Active pharmaceutical ingredients. CAS No. 393-12-4. Product ID: API393124. Molecular formula: C9H7F3N2O3. Mole weight: 248.16.
Fluticasone 17β-Carboxylic Acid
Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate. Category: Active pharmaceutical ingredients. CAS No. 28416-82-2. Product ID: API28416822. Molecular formula: C21H26F2O5. Mole weight: 396.42.
Fluticasone dimer impurity
Fluticasone dimer impurity, a dimeric derivative of Fluticasone Propionate, is a corticosteroid recognized for its high receptor affinity and potent topical activity. Category: Active pharmaceutical ingredients. CAS No. 220589-37-7. Product ID: API220589377. Molecular formula: C43H51F5O8S. Mole weight: 822.92.
Fluticasone Propionate-d5
Fluticasone Propionate-d5 is a deuterated compound of Fluticasone Propionate. Fluticasone Propionate has a CAS number of 80474-14-2. Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. Category: Active pharmaceutical ingredients. CAS No. 1093258-28-6. Product ID: API1093258286. Molecular formula: C25H26D5F3O5S. Mole weight: 505.6.
Flutrimazole
Flutrimazole is a dual-action imidazole antifungal compound, exhibiting both anti-inflammatory and antifungal properties. Notably, flutrimazole demonstrates limited transdermal penetration, making it particularly advantageous for topical applications in the treatment of fungal infections, especially those accompanied by inflammation. Category: Active pharmaceutical ingredients. CAS No. 119006-77-8. Product ID: API119006778. Molecular formula: C22H16F2N2. Mole weight: 346.37.
Fluvastatin sodium
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent. Category: Active pharmaceutical ingredients. CAS No. 93957-55-2. Product ID: API93957552. Molecular formula: C24H25FNNaO4. Mole weight: 433.45.
Fluvastatin sodium monohydrate
Fluvastatin (XU 62-320) sodium monohydrate, a fully synthetic competitive HMG-CoA reductase inhibitor, features an IC 50 of 8 nM. This compound also safeguards vascular smooth muscle cells from oxidative stress via the Nrf2-dependent antioxidant pathway. Category: Active pharmaceutical ingredients. Synonyms: XU 62-320 monohydrate. CAS No. 201541-53-9. Product ID: API201541539. Molecular formula: C24H27FNNaO5. Mole weight: 451.46.
Fluvoxamine-d3 Maleate
Fluvoxamine-d3 Maleate is a deuterated compound of Fluvoxamine Maleate. Fluvoxamine Maleate has a CAS number of 61718-82-9. Fluvoxamine maleate is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders. Category: Active pharmaceutical ingredients. CAS No. 1185245-56-0. Product ID: API1185245560. Molecular formula: C19H22D3F3N2O6. Mole weight: 437.43.
Fluzoparib
Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours. Category: Active pharmaceutical ingredients. CAS No. 1358715-18-0. Product ID: API1358715180. Molecular formula: C22H16F4N6O2. Mole weight: 472.4.
Fmoc-N-methyl-D-leucine
Fmoc-N-methyl-D-leucine is an N-methylated derivative of D-leucine with Fmoc protection. N-methylation of the backbone is a critical modification for enhancing the therapeutic potential of synthetic peptides. Applications: It is a vital intermediate for the synthesis of cyclic peptides, peptidomimetics, and drug candidates aimed at improving oral bioavailability and overcoming protease degradation. Category: Intermediates. Synonyms: N-ALPHA-FMOC-N-ALPHA-METHYL-D-LEUCINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-D-LEUCINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-D-LEUCINE. CAS No. 103478-63-3. Product ID: INT103478633. Molecular formula: C22H25NO4. Mole weight: 367.44. InChIKey: BUJQSIPFDWLNDC-HXUWFJFHSA-N. Appearance: Off-white solid.
FMOC-N-Methyl-L-alanine
FMOC-N-Methyl-L-alanine is the Fmoc-protected form of N-methyl-L-alanine, providing the smallest possible N-methylated amino acid building block for synthetic applications. Applications: It is widely used in the synthesis of cyclic peptides and in the study of peptide folding and protein-protein interaction inhibitors. Category: Intermediates. Synonyms: (9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-Ala-OH. CAS No. 84000-07-7. Product ID: INT84000077. Molecular formula: C19H19NO4. Mole weight: 325.36. EINECS: 1533716-785-6. InChIKey: JOFHWKQIQLPZTC-LBPRGKRZSA-N. Appearance: White to off-white solid.
FMOC-STA-OH
FMOC-STA-OH (Fmoc-Statine) is a gamma-amino-beta-hydroxy acid derivative. Statine is a non-natural amino acid that acts as a transition-state analog for aspartic proteases, making this Fmoc-protected version a powerful tool in drug design. Applications: It is a critical component in the synthesis of potent protease inhibitors (e.g., pepstatin analogs) used in the treatment of hypertension, alzheimer's, and viral infections. Category: Intermediates. Synonyms: FMOC-STATINE;FMOC-LEU-STATINE;FMOC-(3S,4S)-4-AMINO-3-HYDROXY-6-METHYL HEPTANOIC ACID;FMOC-(3S,4S)-STA-OH;(3S,4S)-4-(FMOC-AMINO)-3-HYDROXY-6-METHYLHEPTANOIC ACID. CAS No. 158257-40-0. Product ID: INT158257400. Molecular formula: C23H27NO5. Mole weight: 397.46. InChIKey: JGUYYODGVQXZAY-SFTDATJTSA-N. Appearance: White to off-white solid.
Follistatin
Mature follistatin is composed of an N-terminal distinct domain (Fs0), and three follistatin domains (Fs1, 2, 3). There are three main isoforms of follistatin that have different C-terminal tails. These isoforms are produced through various combinations of alternative splicing and proteolytic processing. The main functional difference between isoforms is in their binding affinity towards heparan sulphates (HS). The shortest isoform (Fs288) has the highest affinity for HS, while the longest isoform (Fs315) with its acidic tail has no ability to bind HS. Applications: Because follistatin inhibits myostatin, follistatin therapies are potential treatments for muscle-wasting diseases such as muscular dystrophy and sarcopenia. neutralization of activin and bmps also may have therapeutic potential in diseases of reproduction, osteoporosis, and metabolic syndromes. Category: Hormones. Synonyms: FS; FSActivin-binding protein; FST. Product ID: 92530ES. Mole weight: Approximately 31.5 kDa. Appearance: Sterile filtered white lyophilized (freeze-dried) powder.