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Fosaprepitant dimeglumine
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, a water-soluble, N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent selectively binds to human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS), inhibiting receptor binding of endogenous substance P and preventing substance P-induced emesis. Category: Active pharmaceutical ingredients. CAS No. 265121-04-8. Product ID: API265121048. Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83.
Fosclevudine alafenamide
Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent with activity against HBV (EC50: 1.71 μM). Category: Active pharmaceutical ingredients. CAS No. 1951476-79-1. Product ID: API1951476791. Molecular formula: C22H29FN3O9P. Mole weight: 529.45.
Fosfluconazole
Fosfluconazole is water-soluble phosphate prodrug of fluconazole. Fluconazole is an antifungal drug. Category: Active pharmaceutical ingredients. CAS No. 194798-83-9. Product ID: API194798839. Molecular formula: C13H13F2N6O4P. Mole weight: 386.25.
Fosfomycin Tromethamine
Fosfomycin tromethamine is a broad-spectrum phosphonic acid antibiotic administered as a single oral dose for uncomplicated urinary tract infections. The tromethamine salt enhances water solubility and gastrointestinal absorption. Applications: Fosfomycin tromethamine is indicated for uncomplicated lower urinary tract infections (acute cystitis) in women caused by escherichia coli and enterococcus faecalis. a single 3-gram dose achieves therapeutic urinary concentrations for 48-72 hours. it is particularly useful for patients with frequent recurrences, antibiotic allergies, or infections with resistant strains. Category: Active pharmaceutical ingredients. Synonyms: Fosfomycin trometamol salt; 7FXW6U30GY; Z 1282; Fosfomycin compound with Trometamol; (1R,2S)-(1,2-Epoxypropyl)phosphonic Acid, compound with 2-Amino-2-(hydroxymethyl)-1,3-propanediol(1:1). CAS No. 78964-85-9. Product ID: API0231625. Molecular formula: C7H18NO7P. Mole weight: 259.19. EINECS: 279-018-8. InChIKey: QZJIMDIBFFHQDW-LMLSDSMGSA-N. Appearance: White to off-white hygroscopic powder.
Fosifloxuridine nafalbenamide
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells. Category: Active pharmaceutical ingredients. CAS No. 1332837-31-6. Product ID: API1332837316. Molecular formula: C29H29FN3O9P. Mole weight: 613.53.
Fosravuconazole L-lysine ethanolate
Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate) is a broad-spectrum antifungal agent approved in Japan for treating onychomycosis, a fungal nail infection. It is a prodrug converted into ravuconazole. Category: Active pharmaceutical ingredients. CAS No. 914361-45-8. Product ID: API914361458. Molecular formula: C31H40F2N7O8PS. Mole weight: 739.7.
Frovatriptan Succinate
Frovatriptan Succinate is a selective 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptor agonist (triptan) used for the acute treatment of migraine attacks with or without aura. It is marketed as the succinate salt and is distinguished among triptans by its notably long terminal half-life (approximately 26 hours), which provides sustained receptor engagement and may contribute to lower recurrence rates. Applications: Frovatriptan succinate is indicated for the acute treatment of migraine attacks with or without aura in adults. its long half-life makes it particularly suitable for patients experiencing migraines with prolonged duration or those with a history of migraine recurrence. Category: Active pharmaceutical ingredients. Synonyms: (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide butanedioate;1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-, (3R)-, butanedioate. CAS No. 158930-09-7. Product ID: API158930097. Molecular formula: C18H23N3O5. Mole weight: 361.4. InChIKey: WHTHWNUUXINXHN-SBSPUUFOSA-N.
Fructooligosaccharides (Oligolevulose) is a beneficial sugar which can be produced by the microbial flora. Fructooligosaccharides had no significant effect on blood glucose, blood lipid and serum acetate in diabetic model. Category: Chemicals. Synonyms: FOS. FRUCTOOLIGOSACCHARIDES. FRUCTOOLIGOSACCHARIDE, 80%-90%. FructooIigsacccharids. Oligolevulose. Beneo p 95. Fortifeed. Fos-p power 300. CAS No. 308066-66-2. Product ID: CHE308066662. Molecular formula: C6H12O6.
Fructose
Fructose, isolated from the leaves of Ginkgo biloba L, is transported into neocortical cells, including nerve terminals, and that it is metabolized and thereby detoxified primarily through hexokinase activity. High-Fructose intake induces nonalcoholic fatty liver disease (NAFLD) and chronic intermittent hypobaric hypoxia (CIHH) has beneficial effects on the body. Category: Apis for liver disease. Synonyms: beta-D-Fructopyranose. Frutabs. laevoral. laevosan. CAS No. 7660-25-5. Product ID: API7660255. Molecular formula: C6H12O6. Mole weight: 180.16. SMILES: C1C(C(C(C(O1)(CO)O)O)O)O. Appearance: White crystals.
Fulvestrant
Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30. Fulvestrant has antitumor activity, inhibiting cell proliferation and inducing apoptosis and autophagy. Category: Active pharmaceutical ingredients. CAS No. 129453-61-8. Product ID: API129453618. Molecular formula: C32H47F5O3S. Mole weight: 606.77.
Fulvestrant 3-β-D-Glucuronide
Fulvestrant 3-β-D-Glucuronide, a glucuronide and sulfate conjugate metabolite of the pure anti-estrogenic steroid Fulvestrant, is utilized in breast cancer research. Category: Active pharmaceutical ingredients. CAS No. 261506-27-8. Product ID: API261506278. Molecular formula: C38H55F5O9S. Mole weight: 782.9.
Fulvestrant R enantiomer
Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. Category: Active pharmaceutical ingredients. CAS No. 1807900-80-6. Product ID: API1807900806. Molecular formula: C32H47F5O3S. Mole weight: 606.77.
Fulvestrant (S enantiomer)
Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM. Category: Active pharmaceutical ingredients. Synonyms: ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer. CAS No. 1316849-17-8. Product ID: API1316849178. Molecular formula: C32H47F5O3S. Mole weight: 606.77.
Fulvestrant sulfone
Fulvestrant sulfone is a synthetic estrogen receptor antagonist. Category: Active pharmaceutical ingredients. CAS No. 98008-06-1. Product ID: API98008061. Molecular formula: C32H47F5O4S. Mole weight: 622.77.
Furazolidone
Furazolidone is a nitrofuran derivative that exhibits both antiprotozoal and antibacterial activity. It is a small molecule drug that binds to bacterial DNA, which leads to the gradual inhibition of monoamine oxidase. The drug is rapidly and extensively metabolized, primarily via nitro-reduction to an aminofuran derivative. Applications: It has been used for the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms. clinical applications have included the treatment of giardiasis, amoebiasis, trichomoniasis, and bacterial colitis. Category: Active pharmaceutical ingredients. Synonyms: Furoxone; Nitrofurazolidone; Furazolidine; Nitrofuroxon; Diafuron; Neftin; Furaxone; Furazolidon. CAS No. 67-45-8. Product ID: API0231569. Molecular formula: C8H7N3O5. Mole weight: 225.16. EINECS: 200-653-3. InChIKey: PLHJDBGFXBMTGZ-WEVVVXLNSA-N. Appearance: Light yellow crystalline powder.
Furosemide
Furosemide is a potent, loop diuretic belonging to the sulfonamide class, widely used to manage fluid overload. FDA-approved since the early 1980s, it is characterized by rapid onset and short duration of action. Applications: Furosemide is indicated for edema associated with congestive heart failure, hepatic cirrhosis, and renal disease, including nephrotic syndrome. it is also used as adjunctive therapy for acute pulmonary edema and for management of hypertension. therapy is contraindicated in anuria and in patients with hypersensitivity to sulfonamides. Category: Diuretic apis. Synonyms: Frusemide, Lasix, Furanthril. CAS No. 54-31-9. Product ID: API0232827. Molecular formula: C12H11ClN2O5S. Mole weight: 330.74. EINECS: 200-203-6. InChIKey: ZZUFCTLCJUWOSV-UHFFFAOYSA-N. Appearance: White to off-white powder.
Fursultiamine
Fursultiamine is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency. It acts by modulating the activity of various enzymes, hormones, and neurotransmitters, as well as by exerting antioxidant and anti-inflammatory effects. Specific enzymes that it inhibits include acetylcholinesterase, monoamine oxidase, and cyclooxygenase. Category: Active pharmaceutical ingredients. CAS No. 804-30-8. Product ID: API804308. Molecular formula: C17H26N4O3S2. Mole weight: 398.543.
Gaboterate Meglumine
a macrocycle-structured gadolinium-based MRI contrast agent. Category: Active pharmaceutical ingredients. CAS No. 92943-93-6. Product ID: API92943936. Molecular formula: C23H42GdN5O13. Mole weight: 753.855.
Gadobutrol
Gadobutrol. Category: Active pharmaceutical ingredients. CAS No. 138071-82-6. Product ID: API138071826. Molecular formula: C18H31GdN4O9. Mole weight: 604.71.
Ganciclovir
Ganciclovir is an antiviral prescription medicine for the treatment of cytomegalovirus retinitis (CMV retinitis) in adults who are immunocompromised, including individuals with AIDS. Category: Other apis. Synonyms: Cytovene. Gancyclovir. Vitrasert. Grades: DMF/GMP. CAS No. 82410-32-0. Product ID: API82410320. Molecular formula: C9H13N5O4. Mole weight: 255.23. EINECS: 627-054-3. SMILES: C1=NC2=C(N1COC(CO)CO)N=C(NC2=O)N. Appearance: White to off-white solid. Standard: CP/EP/USP.
Ganirelix
Ganirelix acetate (Ganirest) is an injectable competitive gonadotropin-releasing hormone (GnRH) antagonist. Ganirelix acetate directly competes against the endogenous molecule for receptor binding, and causes a rapid reduction in estradiol levels. Ganirelix acetate can be used for researching ovarian hyperstimulation syndrome (OHSS). Category: Active pharmaceutical ingredients. CAS No. 129311-55-3. Product ID: API129311553. Molecular formula: C84H121ClN18O17. Mole weight: 1690.423.
Ganirelix Acetate
Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 123246-29-7. Product ID: API123246297. Molecular formula: C80H113ClN18O13. Mole weight: 1570.34. Standard: GMP.
Garenoxacin
Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections. Category: Active pharmaceutical ingredients. CAS No. 194804-75-6. Product ID: API194804756. Molecular formula: C23H20F2N2O4. Mole weight: 426.41.
Garenoxacin mesylate
Garenoxacin mesylate, a novel oral des-fluoro quinolone, has potent antimicrobial activity against common respiratory pathogens, including resistant strains and Gram-negative and Gram-positive bacterial infections. Category: Active pharmaceutical ingredients. Synonyms: Garenoxacin mesilate,BMS 284756,BM-284756,BMS284756. CAS No. 223652-82-2. Product ID: API223652822. Molecular formula: C24H24F2N2O7S. Mole weight: 522.52.
Garenoxacin mesylate hydrate
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. Category: Active pharmaceutical ingredients. Synonyms: Garenoxacin mesylate [USAN], BMS284756 (Mesylate hydrate). CAS No. 223652-90-2. Product ID: API223652902. Molecular formula: C23H20F2N2O4.CH4O3S.H2O. Mole weight: 540.53.
Gatifloxacin
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 112811-59-3. Product ID: API112811593. Molecular formula: C19H22FN3O4. Mole weight: 375.39.
Gatifloxacin hydrochloride
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a fourth-generation fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 121577-32-0. Product ID: API121577320. Molecular formula: C19H23ClFN3O4. Mole weight: 411.86.
Gatifloxacin mesylate
Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family.It also inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 316819-28-0. Product ID: API316819280. Molecular formula: C20H26FN3O7S. Mole weight: 471.5.
Gatifloxacin sesquihydrate
Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia. Category: Active pharmaceutical ingredients. CAS No. 180200-66-2. Product ID: API180200662. Molecular formula: C19H24FN3O5. Mole weight: 393.41.
Gefitinib
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation. Category: Active pharmaceutical ingredients. CAS No. 184475-35-2. Product ID: API184475352. Molecular formula: C22H24ClFN4O3. Mole weight: 446.9.
Gefitinib-d6
Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM). Category: Active pharmaceutical ingredients. CAS No. 1228664-49-0. Product ID: API1228664490. Molecular formula: C22H18D6ClFN4O3. Mole weight: 452.94.
Gefitinib-d8ZD1839 D8, Gefitinib D8
Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8is a deuterium labeled Gefitinib. Category: Active pharmaceutical ingredients. CAS No. 857091-32-8. Product ID: API857091328. Molecular formula: C22H24ClFN4O3. Mole weight: 454.95.
Gefitinib dihydrochloride
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib dihydrochloride induces autophagy and apoptosis, and can be used in studies of cancer-related diseases such as lung and breast cancer. Category: Active pharmaceutical ingredients. CAS No. 184475-56-7. Product ID: API184475567. Molecular formula: C22H26Cl3FN4O3. Mole weight: 519.82.
GEM-5
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth. Category: Active pharmaceutical ingredients. CAS No. 2233543-49-0. Product ID: API2233543490. Molecular formula: C32H29F2N5O8. Mole weight: 649.6.
Gemcitabine
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Category: Active pharmaceutical ingredients. CAS No. 95058-81-4. Product ID: API95058814. Molecular formula: C9H11F2N3O4. Mole weight: 263.2.
Gemcitabine elaidate
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine 5'-elaidate, Gemcitabine (elaidate), CO-101, CP-4126. CAS No. 210829-30-4. Product ID: API210829304. Molecular formula: C27H43F2N3O5. Mole weight: 527.64.
Gemcitabine elaidate hydrochloride
Gemcitabine elaidate (CP-4126) hydrochloride is a lipophilic pro-drug of Gemcitabine, converted to Gemcitabine by esterases for phosphorylation. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine elaidate hydrochloride(210829-30-4(free base)), Gemcitabine 5'-elaidate hydrochloride, CP-4126 hydrochloride, CO-101 hydrochloride. CAS No. 2918768-08-6. Product ID: API2918768086. Molecular formula: C27H44ClF2N3O5. Mole weight: 564.11.
Gemcitabine hydrochloride
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine HCl, Gemzar, LY 188011 hydrochloride. CAS No. 122111-03-9. Product ID: API122111039. Molecular formula: C9H11F2N3O4·HCl. Mole weight: 299.66.
Gemcitabine monophosphate
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. Category: Active pharmaceutical ingredients. Synonyms: GemMP, Gemcitabine 5-phosphate. CAS No. 116371-67-6. Product ID: API116371676. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine triphosphate
Gemcitabine triphosphate (dFdCTP), alongside its counterpart, the active diphosphate (dFdCDP), represents one of the two primary nucleoside metabolites of Gemcitabine within cellular structures. Category: Active pharmaceutical ingredients. CAS No. 110988-86-8. Product ID: API110988868. Molecular formula: C9H14F2N3O13P3. Mole weight: 503.14.
Gemifloxacin
Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect. Category: Active pharmaceutical ingredients. Synonyms: SB-265805. CAS No. 175463-14-6. Product ID: API175463146. Molecular formula: C18H20FN5O4. Mole weight: 389.38.
Gemifloxacin mesylate
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. This fluoroquinolone exerts an enhanced spectrum of activity against gram-positive bacteria such as Streptococcus pneumonia and Staphylococcus aureus, in addition to its activity against gram-negative bacteria. Category: Active pharmaceutical ingredients. CAS No. 210353-53-0. Product ID: API210353530. Molecular formula: C19H24FN5O7S. Mole weight: 485.49.
Gemigliptin
Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.). Category: Active pharmaceutical ingredients. CAS No. 911637-19-9. Product ID: API911637199. Molecular formula: C18H19F8N5O2. Mole weight: 489.36.
Gemigliptin Tartrate
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Category: Active pharmaceutical ingredients. CAS No. 1374639-74-3. Product ID: API1374639743. Molecular formula: C22H25F8N5O8. Mole weight: 639.45.
Gentisic acid
2,5-Dihydroxybenzoic Acid is an active metabolite of salicylic acid degradation. Evidence indicates that gentisic acid has anti-inflammatory, antirheumatic and antioxidant properties. It is also a byproduct of both tyrosine and benzoate metabolisms. Category: Antioxidant excipients. Synonyms: 2,5-DIHYDROXYBENZOIC ACID. Hydroquinonecarboxylic acid. Benzoic acid, 2,5-dihydroxy-. CAS No. 490-79-9. Product ID: PIE-0313. Molecular formula: C7H6O4. Mole weight: 154.12. EINECS: 207-718-5. SMILES: C1=CC(=C(C=C1O)C(=O)O)O. Appearance: Light yellow crystals.
Ginkgo Biloba Extract
Ginkgo Biloba Extract is a standardized form of extract that is made from the leaves of Ginkgo biloba trees. By standardizing this extract, unwanted levels of naturally occurring impurities such as ginkgolic acids are removed. This ensures that the standardized version of the herb contains the desired concentrations of bioactive components so they can be used for pharmaceutical studies and nutraceutical development. Applications: Uses for ginkgo biloba extract include supporting cognitive function, memory, and increasing blood flow to the brain. it is also commonly used when developing treatments targeting peripheral vascular disease and ocular symptoms like ringing in the ears (tinnitus). Category: Natural extract. Product ID: PIPE-0023. Appearance: Powder.
Glatiramer
an immunomodulator used to reduce the frequency of relapses in Multiple Sclerosis (MS). Category: Active pharmaceutical ingredients. CAS No. 28704-27-0. Product ID: API28704270. Molecular formula: C23H41N5O11. Mole weight: 563.599.
Glecaprevir
Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM). Category: Active pharmaceutical ingredients. CAS No. 1365970-03-1. Product ID: API1365970031. Molecular formula: C38H46F4N6O9S. Mole weight: 838.87.
Glucagon hydrochloride
Glucagon is a peptide hormone produced from proglucagon in pancreatic α cells that has a role in the regulation of glucose metabolism. Category: Active pharmaceutical ingredients. CAS No. 19179-82-9. Product ID: API19179829. Molecular formula: C153H225N43O49S; XHCl. Mole weight: 3482.8.
Glucurolactone
Adjuvant and antidote for liver diseases, for acute and chronic hepatitis, cirrhosis of the liver, or for the detoxification of food or drug poisoning. Category: Apis for liver disease. Synonyms: D-Glucurono-3,6-lactone. GLUCUROLACTONE. D-Glucurono-6,3-lactone. Glucurone. CAS No. 32449-92-6. Product ID: API32449926. Molecular formula: C6H8O6. Mole weight: 176.12. EINECS: 251-053-3. SMILES: C(=O)C(C1C(C(C(=O)O1)O)O)O. Standard: WS1-(YH-002)-1995-2021.
Glutathione
Glutathione, reduced is an endogenous antioxidant, representative of the cellular oxidative state. Category: Active pharmaceutical ingredients. CAS No. 70-18-8. Product ID: API70188. Molecular formula: C10H17N3O6S. Mole weight: 307.32. Appearance: Crystalline.
Glutethimide
Glutethimide is a hypnotic and sedative that was introduced in 1954 as a potential non-barbiturate alternative for the treatment of insomnia. Applications: Glutethimide was originally indicated for the treatment of insomnia, but its use has now been largely superseded by other drugs with better safety profiles. its historical use has also included the treatment of essential tremor and intention tremor, with evidence suggesting efficacy. Category: Active pharmaceutical ingredients. Synonyms: Doriden; Sarodormin; Elrodorm; Noxyron; Glutethimid; Gluthetimide; Glutetimid; Rigenox; Glutathimid; Glutetimide; Glimid; 2-Ethyl-2-phenylglutarimide. CAS No. 77-21-4. Product ID: API0231568. Molecular formula: C13H15NO2. Mole weight: 217.26. EINECS: 201-012-0. InChIKey: JMBQKKAJIKAWKF-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder.
Glycerin
Glycerin (1,2,3-propanetriol) is a colorless, odorless, viscous liquid with a sweet taste. It is a simple polyol compound. It contains three hydroxyl groups. As a result of this, glycerol is highly hydrophilic, hygroscopic, has a high boiling point and low volatility. It is both metabolically produced in the human body and by various microorganisms (including Escherichia coli and yeast) as well as a nontoxic, biodegradable, environmentally friendly compound. Applications: Glycerol has many uses in biotechnology, pharmaceutical industry and preserving samples. it is commonly used in laboratories for electrophoresis, as it helps increase the density of samples to allow easier and more accurate pipetting into the wells of the gel, as well as acting as a protein stabilizer. enzymes are stabilized using glycerol for the same reasons. glycerol is widely used as a cryoprotectant for cell culture and microbiology applications; because glycerol depresses freezing temperature and inhibits damaging ice formation, glycerol allows bacterial cultures to be frozen at -80 °c for long term storage. outside the laboratory, glycerol is used as an emollient and humectant in soaps and cosmetics and is used in pharmaceutical preparations due to its non-toxicity as a solvent. Category: Solvents. Synonyms: Glycerol; Glycerine; 1,2,3-trihydroxypropane. CAS No. 56-81-5. Product ID: CHE56815. Molecular formula: C3H8O3. Mole weight: 92.09. EINECS: 200-289-
Glycine
It has a role as a nutraceutical, a hepatoprotective agent, an EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor, a NMDA receptor agonist, a micronutrient, a fundamental metabolite and a neurotransmitter. Category: Amino acids and derivatives. Synonyms: 2-Aminoacetic acid. aminoacetic acid. Glycocoll. CAS No. 56-40-6. Product ID: API56406. Molecular formula: C2H5NO2. Mole weight: 75.07. EINECS: 200-272-2. SMILES: C(C(=O)O)N. Appearance: white crystals. Standard: USP,AJI,EP,CP.
Golodirsen
Golodirsen is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD). Category: Active pharmaceutical ingredients. CAS No. 1422959-91-8. Product ID: API1422959918.
Goserelin Acetate
Goserelin Acetate is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH) formulated as an acetate salt. It is designed for sustained therapeutic activity and contains specific amino acid substitutions D-Ser(Bu(t)) at position 6 and Azagly-NH2 at position 10 that enhance receptor binding and metabolic stability. Applications: Indicated for the treatment of hormone-dependent cancers including prostate cancer, breast cancer, and endometriosis. goserelin acetate is a gnrh agonist that provides sustained suppression of gonadal steroidogenesis through continuous receptor downregulation. it is administered as a long-acting depot implant formulation. Category: Active pharmaceutical ingredients. CAS No. 145781-92-6. Product ID: API145781926. Molecular formula: C61H88N18O16. Mole weight: 1329.5. EINECS: 652-995-1. InChIKey: IKDXDQDKCZPQSZ-JHYYTBFNSA-N. Appearance: White to off-white powder.
Granisetron hydrochloride
Granisetron Hcl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Category: Active pharmaceutical ingredients. CAS No. 107007-99-8. Product ID: API107007998. Molecular formula: C18H24N4O HCl. Mole weight: 348.87.
Grazoprevir
Grazoprevir is a second-generation NS3/4A protease inhibitor that is often used in combination with the second-generation NS5A inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1350514-68-9. Product ID: API1350514689. Molecular formula: C38H50N6O9S. Mole weight: 766.9.
Grepafloxacindl
Grepafloxacin (OPC-17116) is a fluoroquinolone antibiotic that is administered orally. It possesses strong efficacy against community-acquired respiratory pathogens, notably Streptococcus pneumonia. Grepafloxacin exhibits excellent tissue penetration and demonstrates a promising pharmacodynamic profile. Category: Active pharmaceutical ingredients. CAS No. 119914-60-2. Product ID: API119914602. Molecular formula: C19H22FN3O3. Mole weight: 359.401.
Grepafloxacin Hydrochloride
Grepafloxacin Hydrochloride is a fluoroquinolone antibacterial agent with a broad spectrum of activity against Gram-positive, Gram-negative, and atypical respiratory pathogens. Its fluorine substituent at the C-6 position and piperazinyl ring at C-7 confer enhanced activity against Streptococcus pneumoniae and improved tissue penetration compared to earlier fluoroquinolones. It was developed specifically for respiratory tract infections. Applications: Grepafloxacin hydrochloride is indicated for the treatment of community-acquired respiratory tract infections including acute exacerbations of chronic bronchitis, community-acquired pneumonia, and bacterial sinusitis caused by susceptible organisms. Category: Active pharmaceutical ingredients. Synonyms: GREPAFLOXACIN HCL;1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride. CAS No. 161967-81-3. Product ID: API161967813. Molecular formula: C19H23ClFN3O3. Mole weight: 395.9. InChIKey: IEPMBYOIQGCVHO-UHFFFAOYSA-N. Appearance: Yellow powder.
Grepafloxacin, (S)-L-Grepafloxacin
Grepafloxacin, (S)- is an oral broad-spectrum fluoroquinolone antibacterial used for the treatment of bacterial infections. Category: Active pharmaceutical ingredients. CAS No. 146761-69-5. Product ID: API146761695. Molecular formula: C19H22FN3O3. Mole weight: 359.39.
Growth Hormone
Growth hormone (GH, somatotropin) is a peptide hormone produced by the anterior pituitary gland. It is a single-chain polypeptide which consists of 191 amino acids. It is crucial in the regulation of growth, metabolism, and cell repair in humans. The secretion of growth hormone is stimulated by growth hormone-releasing hormone (GHRH) and inhibited by somatostatin. Growth hormone is released in a pulsatile manner with highest secretory peaks occurring during sleep and exercise. Applications: Gh is indicated for the treatment of gh deficiency in children and adults, to increase height, muscle mass and bone density. it is also indicated for treatment of turner syndrome, growth failure due to chronic kidney disease and prader-willi syndrome. gh is also used to treat muscle wasting that can follow severe burns and hiv infection. Category: Hormones. Synonyms: GH1; GH; GHN; GH-N; hGH-N; Pituitary Growth Hormone; Growth Hormone 1; Somatotropin. Product ID: 92801ES. Mole weight: Approximately 22 kDa. InChIKey: LEHSKCILCGLHIK-DLRMDCPISA-N. Appearance: Sterile filtered white lyophilized (freeze-dried) powder.
GS-441524
GS-441524 is a pyrrolotriazine, a nitrile, a C-nucleoside, and an aromatic amine. It is a (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile which is 2-substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group. It is an active metabolite of remdesivir. It is a broad-spectrum inhibitor of replication of RNA viruses, with inhibitory activity being confirmed for HCV, parainfluenza and SARS-CoV. It has the drug targets of a drug metabolite, an antiviral agent and an anticoronaviral agent. Applications: Gs-441524 is a potent antiviral nucleoside analogue that has transformed the treatment of previously fatal viral diseases, most notably in feline medicine. it is the parent molecule and primary metabolite of the well-known human antiviral remdesivir. Category: Intermediates. CAS No. 1191237-69-0. Product ID: INT1191237690. Molecular formula: C12H13N5O4. Mole weight: 291.26. EINECS: 857-885-9. InChIKey: BRDWIEOJOWJCLU-LTGWCKQJSA-N. Appearance: White to off-white solid.
GS-566500
GS-566500 is a compound of Sofosbuvir metabolite. Category: Active pharmaceutical ingredients. CAS No. 1233335-78-8. Product ID: API1233335788. Molecular formula: C13H19FN3O9P. Mole weight: 411.27.
GSK9027
GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity. Category: Active pharmaceutical ingredients. CAS No. 1229096-88-1. Product ID: API1229096881. Molecular formula: C27H19F4N3O2S. Mole weight: 525.52.
Guanabenz Acetate
Guanabenz Acetate is the acetate salt of guanabenz, an alpha-2 adrenergic receptor agonist structurally related to clonidine but featuring a 2,6-dichlorobenzylideneaminoguanidine core. It selectively activates central alpha-2 receptors to reduce sympathetic outflow. Applications: Indicated for the treatment of hypertension. guanabenz acetate is a centrally acting alpha-2 adrenergic receptor agonist that reduces sympathetic nerve activity and lowers blood pressure through brainstem-mediated reduction in peripheral vascular resistance. Category: Active pharmaceutical ingredients. Synonyms: ((2,6-dichlorobenzylidene)amino)-guanidinmonoacetate. CAS No. 23256-50-0. Product ID: API23256500. Molecular formula: C10H12Cl2N4O2. Mole weight: 291.13. EINECS: 245-534-7. InChIKey: MCSPBPXATWBACD-GAYQJXMFSA-N. Appearance: White solid.
Guanfacine Hydrochloride
Guanfacine Hydrochloride is a selective alpha-2 adrenergic receptor agonist of the guanidine derivative class. It demonstrates high selectivity for the alpha-2A adrenergic receptor subtype, distinguishing it from less selective alpha-2 agonists such as clonidine. Applications: Indicated for the treatment of hypertension and attention deficit hyperactivity disorder (adhd). guanfacine hydrochloride is a selective alpha-2a adrenergic receptor agonist that provides centrally mediated blood pressure reduction and has demonstrated efficacy in improving attention and impulse control in adhd patients. Category: Active pharmaceutical ingredients. Synonyms: n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride;Guanfacine HCl. CAS No. 29110-48-3. Product ID: API29110483. Molecular formula: C9H10Cl3N3O. Mole weight: 282.5. EINECS: 249-443-3. InChIKey: DGFYECXYGUIODH-UHFFFAOYSA-N. Appearance: White solid.
Gum Arabic
Gum arabic (GA), also known as acacia gum, is a natural exudate of the Acacia senegal and Acacia seyal tree species of Leguminosae family. Chemically, it is a highly branched neutral or slightly acidic heteropolysaccharide. The main chain of GA is a 1,3-linked β-D-galactopyranosyl residue backbone and L-arabinose, L-rhamnose and D-glucuronic acid are the other components. The side chains contain two to five 1,3-linked β-D-galactopyranosyl units, linked to the main chain by a 1,6-linkage. Applications: Gum arabic is one of the most ancient and widely known natural gums. because of its edibility, highly vigorous water solubility, gras (generally recognized as safe) status, absence of aftertaste, and other favorable properties, gum arabic has been extensively used in the food industry. on account of its emulsifying, stabilizing, thickening, and binding properties, it is employed in the manufacture. Category: Thickener excipients. Synonyms: Arabic gum. CAS No. 9000-1-5. Product ID: PIE-0172. Molecular formula: C12H36. Mole weight: 180.41. EINECS: 232-519-5. InChIKey: GPOWYVZNNHYPBM-UHFFFAOYSA-N. Appearance: White powder.
Halcinonide
Halcinonide (Halciderm), a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations. Category: Active pharmaceutical ingredients. CAS No. 3093-35-4. Product ID: API3093354. Molecular formula: C24H32ClFO5. Mole weight: 454.96.