Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Mifepristone | Mifepristone is a progesterone and glucocorticoid antagonist, suppresses VEGF production. Category: Active pharmaceutical ingredients. CAS No. 84371-65-3. Product ID: API84371653. Molecular formula: C29H35NO2. Mole weight: 429.59. Appearance: Powder. |  |
| Milk Thistle Extract | Milk Thistle Extract. Applications: Liver protection in health-care products and medicine. Category: Natural extract. Synonyms: silybummarianum(linn.)gaertn.,extract;silybummarianumextract,ladysthistleextract;Silybum marianum, ext. CAS No. 84604-20-6. Product ID: PIPE-0001. Molecular formula: C25H22O10. Mole weight: 482.43618. EINECS: 283-298-7. Standard: EP/USP. | |
| Milrinone | It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. It has a role as an EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor, a platelet aggregation inhibitor, a vasodilator agent and a cardiotonic drug. It is a pyridone, a nitrile and a member of bipyridines. Category: Active pharmaceutical ingredients. Synonyms: Primacor. Milrinonum. Milrila. CAS No. 78415-72-2. Product ID: API78415722. Molecular formula: C12H9N3O. Mole weight: 211.22. EINECS: 278-903-6. SMILES: CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2. Appearance: Off-white crystalline powder. | |
| Minocycline Hydrochloride | Minocycline, Hydrochloride is a broad-spectrum tetracycline antibiotic that also acts as PARP inhibitor. Category: Active pharmaceutical ingredients. CAS No. 13614-98-7. Product ID: API13614987. Molecular formula: C23H27N3O7 HCl. Mole weight: 493.94. | |
| Mirabegron | Used for the treatment of overactive bladder syndrome. It has a role as a beta-adrenergic agonist. Category: Other apis. Synonyms: Myrbetriq;Betanis;Betmiga. Grades: USMF/DMF/WC/ASMF/KDMF. CAS No. 223673-61-8. Product ID: API223673618. Molecular formula: C21H24N4O2S. Mole weight: 396.51. EINECS: 800-126-3. SMILES: C1=CC=C(C=C1)C(CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O. Appearance: White to Off-White Solid. Standard: USP/In-house/CP Facility GMP. | |
| Mitiglinide Calcium | Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Category: Hypoglycemic apis. Synonyms: Mitiglinide calcium hydrate. Mitiglinide calcium dihydrate. Glufast. UNII-9651C21W3Z. CAS No. 207844-01-7. Product ID: API207844017. Molecular formula: C38H52CaN2O8. Mole weight: 704.9. EINECS: 691-325-2. SMILES: C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].O.O.[Ca+2]. Appearance: White or off-white crystalline powder. Standard: In-house. | |
| Mitoxantrone hydrochloride | Mitoxantrone dihydrochloride is a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Category: Active pharmaceutical ingredients. CAS No. 70476-82-3. Product ID: API70476823. Molecular formula: C22H30Cl2N4O6. Mole weight: 517.403. | |
| Mizolastine | Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. Category: Active pharmaceutical ingredients. CAS No. 108612-45-9. Product ID: API108612459. Molecular formula: C24H25FN6O. Mole weight: 432.49. | |
| Mizolastine dihydrochloride | Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM). It also used in the treatment of hay fever, hives, and other allergic reactions. Category: Active pharmaceutical ingredients. CAS No. 1056596-82-7. Product ID: API1056596827. Molecular formula: C24H27Cl2FN6O. Mole weight: 505.42. | |
| Moexipril Hydrochloride | Moexipril Hydrochloride is the hydrochloride salt of moexipril, a prodrug of the active metabolite moexiprilat, belonging to the class of non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitors. It is structurally characterized by a dicarboxylate group that contributes to its ACE binding affinity. Applications: Indicated for the treatment of hypertension. moexipril hydrochloride is a non-sulfhydryl ace inhibitor prodrug that undergoes hepatic activation to moexiprilat, blocking the conversion of angiotensin i to angiotensin ii and providing effective blood pressure reduction with a favorable safety profile. Category: Active pharmaceutical ingredients. Synonyms: 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylicacid,hydrochloride;(3SChemicalbook)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylicacidhydrochloride. CAS No. 82586-52-5. Product ID: API82586525. Molecular formula: C27H35ClN2O7. Mole weight: 535. EINECS: 617-363-1. InChIKey: JXRAXHBVZQZSIC-JKVLGAQCSA-N. Appearance: White to off-white powder. | |
| Molindone Hydrochloride | Molindone Hydrochloride is an indole (dihydroindolone) antipsychotic agent structurally and pharmacologically distinct from the phenothiazine, thioxanthene, and butyrophenone classes. It possesses both antipsychotic and antidepressant properties, and is characterized by a lower propensity for sedation, weight gain, and hyperprolactinemia compared to many atypical antipsychotics. The unique indole nucleus confers a distinct receptor binding profile. Applications: Molindone hydrochloride is indicated for the treatment of schizophrenia and other psychotic disorders in adults and adolescents. it is valued for its relatively low tendency to cause weight gain, metabolic syndrome, and hyperprolactinemia, making it a useful option for patients in whom these side effects are particularly concerning. Category: Active pharmaceutical ingredients. Synonyms: 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, hydrochloride. CAS No. 15622-65-8. Product ID: API15622658. Molecular formula: C16H25ClN2O2. Mole weight: 312.83. InChIKey: GQWNECFJGBQMBO-UHFFFAOYSA-N. Appearance: Off-white powder. | |
| Mometasone | Mometasone is an inhaled glucocorticoid. Mometasone can be used in mild asthma with a low sputum eosinophil level. Mometasone has the potential for the research of chronic hand eczema and rhinosinusitis. Category: Active pharmaceutical ingredients. CAS No. 105102-22-5. Product ID: API105102225. Molecular formula: C27H30Cl2O6. Mole weight: 521.429. | |
| Moperone Hydrochloride | Moperone Hydrochloride, a dopamine D2-receptor antagonist, is used for the treatment of psychiatric disorders. Category: Active pharmaceutical ingredients. CAS No. 3871-82-7. Product ID: API3871827. Molecular formula: C22H27ClFNO2. Mole weight: 391.91. | |
| Moricizine Hydrochloride | Moricizine hydrochloride (also known as ethmozine) is a phenothiazine derivative with class I antiarrhythmic properties, classified as a class IB agent but with unique characteristics. It was available for the treatment of life-threatening ventricular arrhythmias. Applications: Prior to withdrawal, moricizine was indicated for the treatment of documented ventricular arrhythmias, including sustained ventricular tachycardia, that were life-threatening in nature. it was used after failure of more established antiarrhythmics. the cardiac arrhythmia suppression trial (cast) demonstrated increased mortality in post-myocardial infarction patients, leading to its fall from use. Category: Active pharmaceutical ingredients. Synonyms: Ethmozine; Moracizine hydrochloride; Moricizine HCl; Ethmozin; Etmozin. CAS No. 29560-58-5. Product ID: API0231627. Molecular formula: C22H26ClN3O4S. Mole weight: 464. InChIKey: GAQAKFHSULJNAK-UHFFFAOYSA-N. Appearance: White to yellowish-brown crystalline powder. | |
| Moroxydine Hydrochloride | Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines. Category: Active pharmaceutical ingredients. CAS No. 3160-91-6. Product ID: API3160916. Molecular formula: C6H14ClN5O. Mole weight: 207.661. | |
| Morphine Sulfate | Morphine sulfate is the sulfate salt of morphine, a phenanthrene alkaloid obtained from opium and classified as a Schedule II controlled substance. FDA-approved since 1941, it remains the archetypal opioid analgesic against which all others are compared. Applications: Morphine sulfate is indicated for the management of moderate to severe acute and chronic pain requiring opioid analgesia when alternative treatments are inadequate. it is also used for pain associated with myocardial infarction and as adjunctive treatment for acute pulmonary edema. Category: Anesthetic analgesia apis. Synonyms: Morphabond, Morphine sulphate. CAS No. 64-31-3. Product ID: API0232577. Molecular formula: C34H40N2O10S. Mole weight: 668.76. EINECS: 200-582-8. InChIKey: USAHOPJHPJHUNS-IFCNUISUSA-N. Appearance: White crystalline powder. | |
| Mosapride Citrate | Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist. Category: Active pharmaceutical ingredients. Synonyms: TAK-370 citrate, AS-4370 citrate. CAS No. 112885-42-4. Product ID: API112885424. Molecular formula: C21H25ClFN3O3·C6H8O7. Mole weight: 614.02. | |
| Mosapride citrate dihydrate | Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons. Category: Active pharmaceutical ingredients. CAS No. 636582-62-2. Product ID: API636582622. Molecular formula: C27H35ClFN3O11. Mole weight: 632.04. | |
| Motixafortide | Motixafortide is a novel CXCR4 antagonist with an IC50 vakue of ~1 nM. Category: Active pharmaceutical ingredients. Synonyms: BKT140 (4-fluorobenzoyl); BL-8040; TF14016. CAS No. 664334-36-5. Product ID: API664334365. Molecular formula: C97H144FN33O19S2. Mole weight: 2159.52. | |
| Moxalactam Disodium | Moxalactam disodium is an oxacephem antibiotic, a beta-lactam structurally similar to cephalosporins but with an oxygen atom replacing the sulfur in the dihydrothiazine ring. It was a broad-spectrum, beta-lactamase-stable agent with activity against gram-negative bacilli. Applications: Moxalactam was indicated for serious infections such as meningitis, peritonitis, pneumonia, and bacteremia caused by gram-negative aerobes and anaerobes. Category: Active pharmaceutical ingredients. Synonyms: Moxam; latamoxef disodium; Shiomarin; Disodium latamoxef; Moxalactam disodium salt; Latamoxefum dinatricum. CAS No. 64953-12-4. Product ID: API0231641. Molecular formula: C20H18N6Na2O9S. Mole weight: 564.4. EINECS: 265-288-4. InChIKey: GRIXGZQULWMCLU-HUTAOCTPSA-L. Appearance: White to light yellow powder. | |
| Moxidectin | Moxidectin is a semi-synthetic single component macrolide antibiotic produced by Streptomyces fermentation, and is a derivative of nimoxetine. The macrolide class of antiparasitic drugs consists of two main classes, namely avermectin and Milbemycin. Category: Active pharmaceutical ingredients. CAS No. 113507-06-5. Product ID: API113507065. Molecular formula: C37H53NO8. Mole weight: 639.82. Standard: In House. | |
| Moxifloxacin-13C-d3 | Moxifloxacin-13C-d3 the 13C and deuterated compound of Moxifloxacin. Moxifloxacin has a CAS number of 151096-09-2. Moxifloxacin is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae. Category: Active pharmaceutical ingredients. CAS No. 1246816-75-0. Product ID: API1246816750. Molecular formula: 13CC20D3H22ClFN3O4. Mole weight: 441.9. | |
| MoxifloxacinAvelox, Moxeza | Moxifloxacin (Avelox) is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae. Category: Active pharmaceutical ingredients. CAS No. 151096-09-2. Product ID: API151096092. Molecular formula: C21H24FN3O4. Mole weight: 401.43. | |
| Moxifloxacin-d4 | Moxifloxacin-d4 is a deuterated compound of Moxifloxacin. Moxifloxacin has a CAS number of 151096-09-2. Moxifloxacin is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae. Category: Active pharmaceutical ingredients. CAS No. 1217802-65-7. Product ID: API1217802657. Molecular formula: C21H21D4ClFN3O4. Mole weight: 441.92. | |
| Moxifloxacin hydrochloride | Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as well as atypical pathogens. Moxifloxacin has been linked to mild ALT elevations during therapy and to rare instances of idiosyncratic acute liver injury with symptoms and jaundice. Category: Active pharmaceutical ingredients. CAS No. 186826-86-8. Product ID: API186826868. Molecular formula: C21H25ClFN3O4. Mole weight: 437.89. | |
| mRNA Vaccinia Capping Enzyme GMP-grade | Vaccinia Virus Capping Enzyme is a highly effective, recombinant enzyme manufactured to cGMP standards to ensure regulatory compliance for use in the production of therapeutic mRNA and vaccines. It is supplied as a liquid, clarified and purified from a recombinant source and tested for freedom from endonucleases, exonucleases and RNases. Applications: The most widely used application of vaccinia virus capping enzyme is for in vitro capping of mrna, for high fidelity rna modification. it is essential for the large scale manufacture of mrna therapeutics and vaccines, where successful translation is critical. it is also used in research applications for preparing mrna for in vitro translation assays and for site-specific 5'-end labeling of mrna transcripts for a variety of molecular studies. Category: Biochemical reagents. Grades: DMF. Product ID: PIPB-0795. Appearance: Clear and transparent liquid. Standard: Facility GMP. | |
| MRTX0902 | MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM. Category: Active pharmaceutical ingredients. CAS No. 2654743-22-1. Product ID: API2654743221. Molecular formula: C22H24N6O. Mole weight: 388.47. Appearance: Powder. | |
| m-tolyl adamantane-1-carboxylate | m-tolyl adamantane-1-carboxylate. Category: Active pharmaceutical ingredients. CAS No. 73599-99-2. Product ID: API73599992. Molecular formula: C18H22O2. Mole weight: 270.366. | |
| Murine RNase inhibitor GMP-grade | Murine RNase Inhibitor is a recombinant, GMP grade, highly purified, stabilized protein expressed and purified in E. coli and supplied in liquid form. Oxidation sensitive human or porcine RNase inhibitors contain cysteine residues that are easily oxidized. Murine RNase inhibitor has none of the oxidation sensitive cysteine residues, making this inhibitor much more oxidation resistant. Applications: Murine rnase inhibitor is typically used in sensitive molecular biology applications to protect rna integrity. it is necessary to protect rna during rt-pcr and rt-qpcr, cdna synthesis, in vitro transcription and translation assays and wherever highly sensitive reactions are performed or the structural and functional integrity of rna is required. it has excellent antioxidant activity and is stable at low dtt concentrations. Category: Biochemical reagents. Grades: DMF. Product ID: PIPB-0798. Mole weight: 50 kDa. Standard: Facility GMP. | |
| MY33-3 | MY33-3 is a powerful and specific inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, demonstrating an IC50 value of approximately 0.1 μM. Moreover, MY33-3 exhibits inhibitory activity against PTP-1B with an IC50 value of about 0.7 μM. Additionally, MY33-3 has been shown to effectively decrease ethanol consumption and alleviate neuroinflammation and cognitive dysfunction induced by Sevoflurane. Category: Active pharmaceutical ingredients. CAS No. 2204280-41-9. Product ID: API2204280419. Molecular formula: C16H13F6NS2. Mole weight: 397.4. | |
| MY33-3 hydrochloride | MY33-3 hydrochloride is a potent and selective inhibitor of the protein tyrosine phosphatase RPTPβ/ζ (IC50~0.1 μM) and PTP-1B (IC50~0.7 μM). It also reduces ethanol consumption and alleviates Sevoflurane-induced neuroinflammation and cognitive dysfunction. Category: Active pharmaceutical ingredients. CAS No. 2204280-42-0. Product ID: API2204280420. Molecular formula: C16H14ClF6NS2. Mole weight: 433.86. | |
| Myristoyl Pentapeptide-17 | Myristoyl Pentapeptide-17 activates keratin gene growth and enhances nutrient uptake by hair follicles. Applications: Promoting eyelash growth. Category: Cosmetic ingredients and additives. Synonyms: N2-(1-Oxotetradecyl)-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-lysinamide;Nutmegfivepeptide17;Myr-KLAKK-NH2;N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1,6-diamino-1-oxohexanChemicalbook-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]tetradecanamide;N2-(1-Oxotetradecyl)-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-lys. CAS No. 959610-30-1. Product ID: CIA959610301. Molecular formula: C41H81N9O6. Mole weight: 796.14. EINECS: 200-001-8. SMILES: C(N)(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCC. InChIKey: NFPWMUOQSJXGGZ-ZZTWKDBPSA-N. Appearance: White powder. | |
| N-(1-adamantyl)acetamide | N-Acetyl Adamantamine is a metabolite of Adamantamine. Category: Active pharmaceutical ingredients. CAS No. 880-52-4. Product ID: API880524. Molecular formula: C12H19NO. Mole weight: 193.29. | |
| Nabumetone | Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) of the naphthylalkanone class, administered as a prodrug that is activated following hepatic metabolism. It is available in oral tablets and is characterized by its neutral gastrointestinal tolerability profile relative to other NSAIDs. The drug is a weak inhibitor of cyclooxygenase itself but undergoes rapid first-pass conversion to its active metabolite. Applications: It is indicated for the management of osteoarthritis and rheumatoid arthritis, providing relief of signs and symptoms including pain, swelling, and morning stiffness. the once- or twice-daily dosing schedule offers a convenience advantage over many other nsaids. while associated with a lower incidence of endoscopic ulcers compared to non-selective nsaids, it still carries warnings regarding cardiovascular risk, gastrointestinal bleeding, and renal impairment, as with all nsaids. Category: Nonsteroidal anti-inflammatory (nsaid) apis. Synonyms: Relafen; 4-(6-methoxynaphthalen-2-yl)butan-2-one; Nabumetona; Nabumetonum; BRL-14777. CAS No. 42924-53-8. Product ID: API0231535. Molecular formula: C15H16O2. Mole weight: 228.29. EINECS: 641-917-1. InChIKey: BLXXJMDCKKHMKV-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| NAD+ | NAD+ was first reported in 1906 as a component of yeast extract that can enhance the fermentation rate. Later on, NAD+ was discovered as an essential carrier for hydrogen transfer for redox reaction. As a redox carrier, NAD+ receives hydride from metabolism such as glycolysis, TCA cycle and fatty acid oxidation (FAO) to generate NADH. In addition to being a critical coenzyme for energy metabolism, the critical role of NAD+ has grown to be a co-substrate for various enzymes such as sirtuins, PARPs, CD157, CD73, CD38 and SARM1. Applications: Nad+ supplementation is emerging as a possible therapeutic avenue in a variety of diseases. in particular, rare diseases with premature aging or dna repair defects such as werner syndrome, cockayne syndrome, ataxia-telangiectasia, and xeroderma pigmentosum group a could be potentially treated with nad+ supplementation. it could lead to a variety of benefits by bolstering dna repair capacity, impro. Category: Cosmetic ingredients and additives. Synonyms: β-Nicotinamide adenine dinucleotide hydrate; β-DPN; β-NAD; Coenzyme 1; Cozymase; DPN; Diphosphopyridine nucleotide; NAD; Nadide. CAS No. 53-84-9. Product ID: CIA53849. Molecular formula: C21H27N7O14P2. Mole weight: 663.43. EINECS: 200-184-4. InChIKey: BAWFJGJZGIEFAR-NNYOXOHSSA-N. Appearance: Powder. | |
| Nadroparin calcium | Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. The amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. Category: Active pharmaceutical ingredients. CAS No. 37270-89-6. Product ID: API37270896. | |
| Naftifine Hydrochloride | Naftifine Hydrochloride is a synthetic allylamine antifungal agent with broad-spectrum activity against dermatophytes, yeasts, and molds. It exhibits both fungicidal and fungistatic properties and belongs to the allylamine class of antifungals, characterized by a naphthalene ring system connected through an allylamine linker. Applications: Indicated for the treatment of dermatophytosis, cutaneous candidiasis, and tinea versicolor. naftifine hydrochloride is an allylamine antifungal agent with fungicidal and fungistatic properties, particularly effective against dermatophytes. it provides rapid relief of symptoms including itching, burning, and scaling in superficial fungal infections. Category: Active pharmaceutical ingredients. Synonyms: Naftifine HCl. CAS No. 65473-14-5. Product ID: API65473145. Molecular formula: C21H22ClN. Mole weight: 323.9. EINECS: 620-502-9. InChIKey: OLUNPKFOFGZHRT-YGCVIUNWSA-N. Appearance: White to off-white solid. | |
| Nalfurafine HCl | Nalfurafine HCl. Category: Active pharmaceutical ingredients. Synonyms: Nalfurafine HCl. Remitch. TRK-820. CAS No. 152658-17-8. Product ID: API152658178. Molecular formula: C28H33ClN2O5. Mole weight: 513. EINECS: 845-923-7. SMILES: CN(C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O)C(=O)C=CC7=COC=C7.Cl. | |
| Naltrexone Hydrochloride | Naltrexone hydrochloride is the hydrochloride salt of naltrexone, a synthetic noroxymorphone derivative with competitive opioid antagonist activity. FDA-approved since 1984, it is a Schedule II controlled substance used as part of comprehensive treatment programs. Applications: Naltrexone hydrochloride is fda-approved for alcohol use disorder to reduce heavy drinking and for opioid dependence to prevent relapse in detoxified, opioid-free individuals highly motivated to maintain abstinence. Category: Anesthetic analgesia apis. Synonyms: Naltrexone HCl. CAS No. 16676-29-2. Product ID: API0232108. Molecular formula: C20H23NO4·HCl. Mole weight: 377.86. EINECS: 240-723-0. InChIKey: RHBRMCOKKKZVRY-ITLPAZOVSA-N. Appearance: White, crystalline compound. | |
| Nandrolone | Nandrolone. Category: Apis for androgens. CAS No. 433-22-0. Product ID: API433220. | |
| Nandrolone Phenpropionate | Nandrolone Phenpropionate is an anabolic-androgenic steroid (AAS) featuring nandrolone (19-nortestosterone) esterified with phenylpropionic acid, which produces a moderately long-acting injectable preparation with enhanced anabolic relative to androgenic activity. The phenylpropionate ester attachment slows the release of nandrolone from the injection site, providing sustained blood concentrations for approximately 7-10 days. Applications: Nandrolone phenpropionate is used in the treatment of anemia secondary to chronic renal failure (as an adjunct to erythropoietin therapy), severe catabolic states, and osteoporosis. Category: Active pharmaceutical ingredients. Synonyms: 17b-hydroxyestr-4-en-3-one 17-(3-phenylpropionate). CAS No. 62-90-8. Product ID: API62908. Molecular formula: C27H34O3. Mole weight: 406.6. EINECS: 200-551-9. InChIKey: UBWXUGDQUBIEIZ-QNTYDACNSA-N. Appearance: White to off-white solid. | |
| Naproxen Sodium | Naproxen Sodium is the sodium salt of naproxen, a non-steroidal anti-inflammatory drug (NSAID) of the arylacetic acid type. It is a small molecule inhibitor and a potent analgesic, antipyretic and anti-inflammatory. Applications: Naproxen is used to treat many different causes of pain, such as after injuries (sprains and twists), surgical procedures of all types (general surgery or gynecological surgery), and menstrual cramps (primary dysmenorrhea). it is also used for headache, toothache, migraine, and extra-articular rheumatism. it can be used as an adjuvant in the treatment of infectious diseases in children and adults, because of its antipyretic properties. naproxen is one of the main treatment options for gout, due to its fast onset and excellent analgesic effects. Category: Active pharmaceutical ingredients. Synonyms: Sodium (S)-2-(6-Methoxynaphthalen-2-yl)propanoate; Sodium (2S)-2-(6-Methoxy-2-naphthyl)propanoate; (S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid sodium salt. CAS No. 26159-34-2. Product ID: API26159342. Molecular formula: C14H13NaO3. Mole weight: 252.24. InChIKey: CDBRNDSHEYLDJV-FVGYRXGTSA-M. Appearance: Powder. | |
| Naratriptan Hydrochloride | Naratriptan Hydrochloride is the hydrochloride salt of naratriptan, a second-generation triptan and selective serotonin 5-HT1B/1D receptor agonist. Among the triptan class, naratriptan is distinguished by the highest bioavailability and longest elimination half-life, attributed in part to its piperidine ring structure replacing the pyrrolidine or ethylamine groups found in other triptans. Applications: Indicated for the acute treatment of migraine attacks. naratriptan hydrochloride is a second-generation triptan with the highest oral bioavailability and longest elimination half-life among triptans, providing sustained migraine relief with convenient dosing and favorable tolerability. Category: Active pharmaceutical ingredients. Synonyms: N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide Hydrochloride;Naratriptan HCl. CAS No. 143388-64-1. Product ID: API143388641. Molecular formula: C17H26ClN3O2S. Mole weight: 371.9. InChIKey: AWEZYKMQFAUBTD-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| N-Boc-D-proline | N-Boc-D-proline is the N-tert-butoxycarbonyl protected derivative of D-proline, a cyclic amino acid. This protected form of the unnatural D-enantiomer is essential for the construction of peptides with specific chirality. Applications: It is widely used in the synthesis of peptidomimetics, chiral catalysts, and as a component in peptide-based drugs where d-proline is required to alter metabolic stability or biological activity. Category: Intermediates. Synonyms: (R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;T-BUTYLOXYCARBONYL-D-PROLINE. CAS No. 37784-17-1. Product ID: INT37784171. Molecular formula: C10H17NO4. Mole weight: 215.25. EINECS: 1533716-785-6. InChIKey: ZQEBQGAAWMOMAI-SSDOTTSWSA-N. Appearance: White to off-white solid. | |
| N-Boc-pyrroline | N-Boc-pyrroline (1-Boc-2,5-dihydro-1H-pyrrole) is a protected unsaturated five-membered nitrogen heterocycle (pyrroline) bearing a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom. The N-Boc protection renders the nitrogen non-nucleophilic and base-stable, while the C=C double bond in the ring provides a site for further chemical elaboration through cycloaddition, hydrogenation, or olefin metathesis reactions. Applications: N-boc-pyrroline is used as a versatile protected heterocyclic building block in the synthesis of pharmaceutical intermediates, particularly those targeting the cns, where the pyrrolidine and pyrroline cores are prevalent in receptor ligands and neurotransmitter analogs. it is used in the synthesis of gabaergic compounds, nmda receptor modulators, and sigma receptor ligands. the boc-protected form is preferred for multi-step synthesis due to its stability and ease of removal. Category: Intermediates. Synonyms: 1-tert-Butoxycarbonylpyrroline;2,5-Dihydro-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester. CAS No. 73286-70-1. Product ID: INT73286701. Molecular formula: C9H15NO2. Mole weight: 169.22. InChIKey: YEBDZDMYLQHGGZ-UHFFFAOYSA-N. | |
| N-Carbamylglutamate | Carglumic acid, a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency. Category: Active pharmaceutical ingredients. CAS No. 1188-38-1. Product ID: API1188381. Molecular formula: C6H10N2O5. Mole weight: 190.154. | |
| NCX-6560 | NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin. NCX-6560 inhibits cholesterol biosynthesis in rat smooth muscle cells with an IC50 of 1.9 μM. Category: Active pharmaceutical ingredients. CAS No. 803728-45-2. Product ID: API803728452. Molecular formula: C37H42FN3O8. Mole weight: 675.74. | |
| N-Descyclopropanecarbaldehyde Olaparib | N-Descyclopropanecarbaldehyde Olaparib, an Olaparib analogue, incorporates a DOTA moiety. N-Descyclopropanecarbaldehyde Olaparib is suitable for radiolabeling with F-18 or a fluorophore to visualize tumors using positron emission tomography (PET) or optical imaging. Category: Active pharmaceutical ingredients. CAS No. 763111-47-3. Product ID: API763111473. Molecular formula: C20H19FN4O2. Mole weight: 366.39. | |
| N-Desmethyl-Apalutamide | N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. Category: Active pharmaceutical ingredients. CAS No. 1332391-11-3. Product ID: API1332391113. Molecular formula: C20H13F4N5O2S. Mole weight: 463.41. | |
| N-desmethyl Enzalutamide | N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide. Category: Active pharmaceutical ingredients. CAS No. 1242137-16-1. Product ID: API1242137161. Molecular formula: C20H14F4N4O2S. Mole weight: 450.41. | |
| N-Desmethyl Pimavanserin | N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin, a 5-HT2A receptor inverse agonist, which is used in the treatment of sleep disorders such as insomnia. Category: Active pharmaceutical ingredients. CAS No. 639863-77-7. Product ID: API639863777. Molecular formula: C24H32FN3O2. Mole weight: 413.53. | |
| N-desmethyl Regorafenib N-oxide | N-Desmethyl Regorafenib N-oxide, an active metabolite of the multi-kinase inhibitor regorafenib, originates through the action of the cytochrome P450 (CYP) isoform CYP3A4. This compound demonstrates efficacy in vitro by inhibiting key enzymes such as VEGFR2, Tie2, c-Kit, and B-RAF, and it exhibits tumor growth inhibition in HT-29 mouse xenograft models at a dosage of 1 mg/kg. Category: Active pharmaceutical ingredients. CAS No. 835621-12-0. Product ID: API835621120. | |
| Nebivolol | Nebivolol. Category: Intermediates. Synonyms: (R)-6-fluoro-3,4-dihydro-2-((R)-oxiran-2-yl)-2H-chromene. (2R)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-chromene. CAS No. 197706-50-6. Product ID: INT197706506. Molecular formula: C11H11FO2. Mole weight: 194.2. EINECS: 603-315-7. SMILES: C1CC2=C(C=CC(=C2)F)OC1C3CO3. | |
| Nebivolol hydrochloride | Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients. Category: Active pharmaceutical ingredients. Synonyms: R 065824 hydrochloride, Nebivolol HCl. CAS No. 152520-56-4. Product ID: API152520564. Molecular formula: C22H25F2NO4·HCl. Mole weight: 441.9. | |
| Nedosiran | Nedosiran represents an impactful potential therapeutic for primary hyperoxaluria (PH) with end-stage renal disease (ESRD). Category: Active pharmaceutical ingredients. CAS No. 2266591-83-5. Product ID: API2266591835. Molecular formula: C662H808F19N231O413P57S6Na57. Mole weight: 22,238 Da. | |
| Nefazodone Hydrochloride | Nefazodone Hydrochloride is a synthetic antidepressant compound of the phenylpiperazine class. It is classified as a serotonin receptor modulator and reuptake inhibitor (SARI), notable for its dual action on both serotonin receptors and the serotonin transporter. Applications: Indicated for the treatment of depression and anxiety disorders. nefazodone hydrochloride is a serotonin receptor modulator and reuptake inhibitor (sari) that combines 5-ht2a receptor antagonism with serotonin and norepinephrine reuptake inhibition. it is particularly notable for its favorable effects on sleep architecture and sexual function. Category: Active pharmaceutical ingredients. Synonyms: 2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride. CAS No. 82752-99-6. Product ID: API82752996. Molecular formula: C25H33Cl2N5O2. Mole weight: 506.5. InChIKey: DYCKFEBIOUQECE-UHFFFAOYSA-N. Appearance: White solid. | |
| Neosperidin Dihydrochalcone | It has a role as an environmental contaminant, a xenobiotic, a plant metabolite and a sweetening agent. Category: Antitussive apis. Synonyms: Nhdc. Neohesperidin dc. Neohesperidin dhc. CAS No. 20702-77-6. Product ID: API20702776. Molecular formula: C28H36O15. Mole weight: 612.6. EINECS: 243-978-6. SMILES: CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C(C(=C3)O)C(=O)CCC4=CC(=C(C=C4)OC)O)O)CO)O)O)O)O)O. Appearance: off-white crystals or powder. Standard: CP. | |
| Nepafenac | Nepafenac is a prodrug ophthalmic NSAID (non-steroidal anti-inflammatory drug) designed for topical ocular administration. It is an amide derivative of amfenac (a potent cyclooxygenase inhibitor) linked to a 2-aminoethanesulfonyl group that increases its corneal penetration. Upon reaching the intraocular tissues, nepafenac is hydrolyzed by ocular hydrolases to the active metabolite amfenac, which inhibits both COX-1 and COX-2 enzymes. Applications: Nepafenac is indicated for the treatment of pain and inflammation associated with cataract surgery (postoperative ocular inflammation), and for the reduction in risk of macular edema associated with cataract surgery in diabetic patients. Category: Intermediates. Synonyms: 2-(2-amino-3-benzoyl-phenyl)acetamide;2-Amino-3-benzoylbenzeneacetamide. CAS No. 78281-72-8. Product ID: INT78281728. Molecular formula: C15H14N2O2. Mole weight: 254.28. EINECS: 200-001-8. InChIKey: QEFAQIPZVLVERP-UHFFFAOYSA-N. | |
| Netupitant | Netupitant is a highly potent and selective, orally active neurokinin-1 receptor antagonist with Ki of 0.95 nM. Category: Active pharmaceutical ingredients. CAS No. 290297-26-6. Product ID: API290297266. Molecular formula: C30H32F6N4O. Mole weight: 578.59. | |
| N-hydroxy Riluzole | N-hydroxy Riluzole is a metabolite of the antiglutamatergic agent riluzole. Category: Active pharmaceutical ingredients. CAS No. 179070-90-7. Product ID: API179070907. Molecular formula: C8H5F3N2O2S. Mole weight: 250.2. | |
| Niacinamide | Niacinamide, also known as nicotinamide, is the water-soluble amide form of vitamin B3 (niacin). Unlike nicotinic acid, niacinamide does not cause cutaneous flushing and has different pharmacologic properties. It is incorporated into topical dermatologic preparations for its anti-inflammatory and skin-barrier effects. Applications: Oral niacinamide is indicated for the treatment of pellagra, a deficiency disease caused by inadequate niacin intake. topically, it is used for acne vulgaris, rosacea, and hyperpigmentation due to its anti-inflammatory and melanin-transfer inhibiting properties. additionally, high-dose oral nicotinamide has been shown to reduce the incidence of non-melanoma skin cancers in high-risk patients, an emerging indication supported by randomized trials. Category: Active pharmaceutical ingredients. Synonyms: 3-Pyridinecarboxamide; pyridine-3-carboxamide; Nicotinic acid amide; Aminicotin; Amixicotyn. CAS No. 98-92-0. Product ID: API0231589. Molecular formula: C6H6N2O. Mole weight: 122.12. EINECS: 202-713-4. InChIKey: DFPAKSUCGFBDDF-UHFFFAOYSA-N. Appearance: White crystalline powder. | |
| Niaprazine | Niaprazine is a histamine H1-receptor antagonist exhibiting significant sedative properties. Category: Active pharmaceutical ingredients. CAS No. 27367-90-4. Product ID: API27367904. Molecular formula: C20H25FN4O. Mole weight: 356.44. | |
| Nic-15 | Nic-15 (compound 4n) serves as an anti-constrictive agent targeting the low vascular characteristics of pancreatic tumors. These characteristics enable cancer cells to adapt to the nutrient-deficient tumor microenvironment and develop resistance to treatment. Nic-15 modulates the PI3K/Akt/mTOR pathway and alleviates ER stress induced by Gemcitabine. Category: Active pharmaceutical ingredients. CAS No. 2896739-91-4. Product ID: API2896739914. Molecular formula: C25H26F2O3. Mole weight: 412.47. | |
| Nifedipine | Nifedipine. Category: Anti-acid apis. Synonyms: sodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide. (S)-(-)-Pantoprazole Sodium Salt. L-Pantoprazole sodium. Pantoprazole sodium, (S)-. CAS No. 160488-53-9. Product ID: API160488539. Molecular formula: C16H14F2N3NaO4S. Mole weight: 405.4. SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C([N-]2)C=C(C=C3)OC(F)F)OC.[Na+]. | |
| Niflumic acid | Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis. Category: Active pharmaceutical ingredients. CAS No. 4394-00-7. Product ID: API4394007. Molecular formula: C13H9F3N2O2. Mole weight: 282.22. | |
| Nilotinib hydrochloride | Nilotinib hydrochloride(AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myelogenous leukemia. Category: Active pharmaceutical ingredients. Synonyms: AMN-107 HCl. Grades: DMF/CEP/EMA. CAS No. 923288-95-3. Product ID: API923288953. Molecular formula: C28H23ClF3N7O. Mole weight: 565.98. Standard: CP/EP/USP/In-house; Facility GMP. | |
| Nilotinib hydrochloride dihydrate | Nilotinib hydrochloride dihydrate is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. Category: Active pharmaceutical ingredients. CAS No. 923289-71-8. Product ID: API923289718. Molecular formula: C28H27ClF3N7O3. Mole weight: 602.02. | |
| Nilutamide | Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progestogen, or glucocorticoid receptors. Category: Active pharmaceutical ingredients. CAS No. 63612-50-0. Product ID: API63612500. Molecular formula: C12H10F3N3O4. Mole weight: 317.22. | |
| Nimustine Hydrochloride | Nimustine hydrochloride is a DNA alkylator and cross-linking agent. Category: Active pharmaceutical ingredients. CAS No. 55661-38-6. Product ID: API55661386. Molecular formula: C9H13ClN6O2 HCl. Mole weight: 309.15. | |
| Nirogacestat | Nirogacestat is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. Category: Active pharmaceutical ingredients. Synonyms: PF-3084014. CAS No. 1290543-63-3. Product ID: API1290543633. Molecular formula: C27H41F2N5O. Mole weight: 489.64. | |
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