Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Prasugrel | Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those undergoing PERCUTANEOUS CORONARY INTERVENTIONS. Category: Active pharmaceutical ingredients. CAS No. 150322-43-3. Product ID: API150322433. Molecular formula: C20H20FNO3S. Mole weight: 373.44. |  |
| Prasugrel Hydrochloride | Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome. Category: Active pharmaceutical ingredients. Synonyms: Prasugrel HCl, Effient, PCR 4099 (hydrochloride), LY 640315 Hydrochloride. CAS No. 389574-19-0. Product ID: API389574190. Molecular formula: C20H20FNO3S·HCl. Mole weight: 409.9. | |
| Prasugrel (Maleic acid) | Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. Prasugrel Maleic acid is a thienopyridine and prodrug. Prasugrel Maleic acid also inhibits platelet function. Category: Active pharmaceutical ingredients. CAS No. 389574-20-3. Product ID: API389574203. Molecular formula: C24H24FNO7S. Mole weight: 489.51. | |
| Prednicarbate | Prednicarbate is a synthetic corticosteroid of the diester class, belonging to the glucocorticoid family of steroidal anti-inflammatory agents. Its structure features a prednisolone skeleton with a 17-propionate and 21-ethyl carbonate esterification, which modulates its topical potency and pharmacokinetic profile. The diesterification contributes to enhanced lipophilicity and targeted local activity with reduced systemic absorption. Applications: Prednicarbate is indicated for the topical treatment of inflammatory and pruritic dermatoses responsive to corticosteroid therapy, including atopic dermatitis, eczematous dermatitis, psoriasis, and allergic contact dermatitis. Category: Active pharmaceutical ingredients. Synonyms: [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate. CAS No. 73771-04-7. Product ID: API73771047. Molecular formula: C27H36O8. Mole weight: 488.6. EINECS: 277-590-3. InChIKey: FNPXMHRZILFCKX-KAJVQRHHSA-N. Appearance: White to off-white solid. | |
| Prednisone Acetate | Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties. Category: Active pharmaceutical ingredients. CAS No. 125-10-0. Product ID: API125100. Molecular formula: C23H28O6. Mole weight: 400.46. | |
| Pretomanid(S)-PA 824 | Pretomanid ((S)-PA 824) , a nitroimidazole, is used as an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM. Category: Active pharmaceutical ingredients. CAS No. 187235-37-6. Product ID: API187235376. Molecular formula: C14H12F3N3O5. Mole weight: 359.26. | |
| Prilocaine | Prilocaine is an aminoamide local anesthetic with intermediate duration and potency, commonly used for infiltration and regional nerve blocks. It is available as a plain solution and in combination with lidocaine as a eutectic mixture (EMLA cream) for topical dermal anesthesia. The drug has a lower risk of systemic toxicity than lidocaine due to rapid metabolism. Applications: Prilocaine is used for infiltration anesthesia, peripheral nerve blocks, epidural anesthesia, and as a topical anesthetic (in emla cream) for skin procedures, venous cannulation, and superficial genital surgery. Category: Active pharmaceutical ingredients. Synonyms: Propitocaine; prilocaine base; N-(2-Methylphenyl)-2-(propylamino)propanamide; Prilocaina; Prilocainum. CAS No. 721-50-6. Product ID: API0231616. Molecular formula: C13H20N2O. Mole weight: 220.31. EINECS: 211-957-0. InChIKey: MVFGUOIZUNYYSO-UHFFFAOYSA-N. Appearance: White crystalline powder. | |
| PRO-6E | PRO-6E demonstrates tumor growth inhibition both in vivo and in vitro, alongside inducing cell apoptosis and cell cycle arrest. Category: Active pharmaceutical ingredients. CAS No. 2353493-69-1. Product ID: API2353493691. Molecular formula: C42H44Cl2FN7O7. Mole weight: 848.75. | |
| Procarbazine Hydrochloride | Procarbazine Hydrochloride is an antineoplastic alkylating agent and methylhydrazine derivative used in the combination chemotherapy of Hodgkin's lymphoma and certain brain tumors. It is administered as the hydrochloride salt and acts through multiple mechanisms including DNA alkylation, inhibition of DNA, RNA, and protein synthesis, and induction of chromosomal damage. Applications: Procarbazine hydrochloride is indicated as a component of mopp (mustine, oncovin, procarbazine, prednisone) and other combination chemotherapy regimens for the treatment of hodgkin's lymphoma (stages iii and iv) and is used off-label in the treatment of primary brain tumors including glioblastoma multiforme. Category: Active pharmaceutical ingredients. Synonyms: N-(1-methylethyl)-4-[(2-methylhydrazinyl)methyl]-benzamide,hydrochloride. CAS No. 366-70-1. Product ID: API366701. Molecular formula: C12H20ClN3O. Mole weight: 257.76. EINECS: 206-678-6. InChIKey: DERJYEZSLHIUKF-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Prochlorperazine Edisylate | Phenothiazine antipsychotic; D2 antagonist; antispasmodic. Category: Active pharmaceutical ingredients. CAS No. 1257-78-9. Product ID: API1257789. Molecular formula: C22H30ClN3O6S3. Mole weight: 564.138. | |
| Progabide | Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor. Category: Active pharmaceutical ingredients. CAS No. 62666-20-0. Product ID: API62666200. Molecular formula: C17H16ClFN2O2. Mole weight: 334.77. | |
| Promazine Hydrochloride | Promazine Hydrochloride is a phenothiazine-derived compound belonging to the aliphatic phenothiazine subclass. It is one of the earliest phenothiazine compounds developed for clinical use, possessing a tricyclic ring system with a dimethylaminopropyl side chain at the N-10 position. Applications: Used in the treatment of psychotic disorders including schizophrenia and severe anxiety states. promazine hydrochloride is an aliphatic phenothiazine antipsychotic that acts primarily as a dopamine d2 receptor antagonist. it is also used in the management of nausea, intractable hiccups, and as an adjunct in tetanus treatment. Category: Active pharmaceutical ingredients. Synonyms: 10-(3-(dimethylamino)propyl)-phenothiazinmonohydrochloride;10-(gamma-Dimethylamino-n-propyl)phenothiazine hydrochloride. CAS No. 53-60-1. Product ID: API53601. Molecular formula: C17H21ClN2S. Mole weight: 320.9. EINECS: 200-179-7. InChIKey: JIVSXRLRGOICGA-UHFFFAOYSA-N. Appearance: White solid. | |
| Promethazine Hydrochloride | Promethazine hydrochloride is a phenothiazine derivative antihistamine with potent sedative, antiemetic, and anticholinergic properties. As a first-generation H1 receptor antagonist, promethazine is classified as a prescription medication requiring careful patient monitoring due to its central nervous system depressant effects and potential for respiratory depression, particularly in pediatric populations. Applications: Promethazine hydrochloride is indicated for multiple clinical scenarios including seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, and angioedema. it is widely used for preoperative, postoperative, and obstetric sedation, prevention and control of nausea and vomiting, treatment of motion sickness, and as adjunctive therapy to analgesics for pain management. Category: Antihistamine apis. Synonyms: Promethazine HCl; Dimethyl-(1-methyl-2-phenothiazin-10-ylethyl)amine hydrochloride. CAS No. 58-33-3. Product ID: API0231865. Molecular formula: C17H21ClN2S. Mole weight: 320.88. EINECS: 200-375-2. InChIKey: XXPDBLUZJRXNNZ-UHFFFAOYSA-N. Appearance: White to faint yellow powder. | |
| Proparacaine Hydrochloride | Proparacaine Hydrochloride is a synthetic ester-type local anesthetic agent of the aminobenzoate class. It is specifically designed for ophthalmic surface anesthesia, characterized by rapid onset and short duration of action. Its ester structure differentiates it from amide-type local anesthetics in terms of metabolic pathway and allergenic potential. Applications: Used in ophthalmology for topical surface anesthesia during eye examinations and minor surgical procedures. proparacaine hydrochloride provides rapid-onset, short-duration corneal anesthesia suitable for tonometry, foreign body removal, suture removal, and diagnostic procedures such as gonioscopy and fundus examination. Category: Active pharmaceutical ingredients. Synonyms: 2-[(3-amino-4-propoxyphenyl)-oxomethoxy]ethyl-diethylammoniumchloride;3-amino-4-propoxybenzoicacid2-(diethylamino)ethylesterhydrochloride;alcaine;benzoicacidChemicalbook,3-amino-4-propoxy-,2-(diethylamino)ethylester,hydrochloride;benzoicacid,3-amino-4-propoxy-,2-(diethylamino)ethylester,monohydrochlorid;beta-(diethylamino)ethyl3-amino-4-n-propoxybenzoatehydrochloride. CAS No. 5875-6-9. Product ID: API5875069. Molecular formula: C16H27ClN2O3. Mole weight: 330.8. EINECS: 227-541-7. InChIKey: BFUUJUGQJUTPAF-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Propiolactone | Propiolactone (beta-propiolactone, BPL) is a highly reactive four-membered lactone ring compound. It is a potent alkylating agent and biocidal reagent, capable of inactivating microorganisms and viruses through covalent modification of nucleic acids and proteins. Its high ring strain drives rapid ring-opening reactions with nucleophiles. Applications: Used in vaccine manufacturing for viral inactivation and as a sterilant for biological products. propiolactone is a potent alkylating agent that inactivates viruses and microorganisms through covalent modification of nucleic acids while preserving protein antigen structure, enabling the production of safe inactivated vaccines. Category: Active pharmaceutical ingredients. Synonyms: β-Propiolactone,3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone. CAS No. 57-57-8. Product ID: API57578. Molecular formula: C3H4O2. Mole weight: 72.06. EINECS: 200-340-1. InChIKey: VEZXCJBBBCKRPI-UHFFFAOYSA-N. Appearance: Colorless liquid. | |
| Propranolol Hydrochloride | Propranolol hydrochloride is a synthetic, nonselective beta-adrenergic receptor blocking agent, chemically described as a stable, white crystalline solid that is readily soluble in water and ethanol. As a highly lipophilic compound, it is almost completely absorbed after oral administration but undergoes extensive first-pass hepatic metabolism, resulting in approximately 25% systemic bioavailability. Applications: Propranolol hydrochloride is indicated for management of hypertension, angina pectoris, cardiac arrhythmias, and post-myocardial infarction to reduce mortality. it is also used for prophylaxis of migraine headaches, management of essential tremor, hypertrophic cardiomyopathy, and symptoms of sympathetic overactivity in hyperthyroidism and anxiety disorders. Category: Antihypertensive apis. Synonyms: Propranolol HCl, Anaprilin, Caridolol. CAS No. 318-98-9. Product ID: API0232432. Molecular formula: C16H22ClNO2. Mole weight: 295.8. EINECS: 222-501-5. InChIKey: ZMRUPTIKESYGQW-UHFFFAOYSA-N. Appearance: White or off-white powder. | |
| Propylene Glycol | It is widely used in various liquid preparations and semi-solid preparations for oral or external use. Category: Solvents. Synonyms: propylene glycol. 1,2-propanediol. propane-1,2-diol. 1,2-Propylene glycol. CAS No. 57-55-6. Product ID: CHE57556. Molecular formula: C3H8O2. Mole weight: 76.09. EINECS: 200-338-0. SMILES: CC(CO)O. Appearance: Thick odorless colorless liquid. Standard: ChP/USP/EP/BP/JP, GMP. | |
| Propylene glycol monomethyl ether acetate (PMA) | PMA is excellent industrial solvent with low toxicity and has strong solubility for polar and non-polar substance, which can be used for advanced paint, printing ink as well as some other polymers, including amido, methyl ester, ethyl, polyester, cellulose acetate, glycol acid resin, crylic acid resin, epoxy resin and nitrocellulose, etc. It can also applied as solvent of paint, ink, textile dyestuff and spinning oil. Category: Chemicals. Synonyms: 1-Methoxy-2-propyl acetate. 1-methoxypropan-2-yl acetate. Propylene glycol monomethyl ether acetate. Propylene glycol methyl ether acetate. CAS No. 108-65-6. Product ID: CHE108656. Molecular formula: CH3COOCH( CH3)CH2OCH3. Mole weight: 132.16. EINECS: 203-603-9. SMILES: CC(COC)OC(=O)C. Appearance: Colorless and transparent liquid. | |
| Propylparaben | Propylparaben. Applications: Pharmaceutic aid (antifungal). antimicrobial preservative in foods and cosmetics. Category: Pharmaceutical excipients. Synonyms: Propyl 4-hydroxybenzoate, 99+% 500GR;Propyl 4-hydroxybenzoate, 99+% 5GR;4-HYDROXYBENZOIC ACID N-PROPYL ESTER;PROPYL 4-HYDROXYBENZOATE, PH EUR;PROPYL 4-HYDROXYBENZOATE, 99+%;N-PROPYL P-HYDROXYBENZOATE SIGMAULTRA;PropylParabenPropylParabenBp/Usp/Ep;Propyl-4-HydroxybenzoateExtraPure. CAS No. 94-13-3. Product ID: PIE-0088. Molecular formula: C10H12O3. Mole weight: 180.2. Appearance: White to off-white solid. Standard: ChP/NF/EP/JP. | |
| Protamine Sulfate | Antiheparin drugs. Category: Active pharmaceutical ingredients. CAS No. 98001-69-5. Product ID: API98001695. Molecular formula: C20H22N8O5. Mole weight: 454.43. Standard: Chinese Pharmacopoeia 2015 Edition Part 2. | |
| Protriptyline Hydrochloride | Protriptyline hydrochloride is a secondary amine tricyclic antidepressant with activating properties, unlike the sedating effects of other TCAs. It is one of the least sedating agents in its class. The drug has a long half-life and is typically dosed once or twice daily. Applications: Protriptyline is indicated for major depressive disorder, particularly in patients with psychomotor retardation, apathy, or anergy. it is also used off-label for narcolepsy (to reduce cataplexy and excessive daytime sleepiness) and for attention-deficit/hyperactivity disorder (adhd) in children. Category: Active pharmaceutical ingredients. Synonyms: Protriptyline HCl; Concordin; Maximed; Triptil hydrochloride; MK-240; NSC-169912; DTXSID8046951. CAS No. 1225-55-4. Product ID: API0231626. Molecular formula: C19H22ClN. Mole weight: 299.8. EINECS: 214-956-3. InChIKey: OGQDIIKRQRZXJH-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Pro-xylane | Hydroxypropyl tetrahydropyrantriol has been used in trials studying the basic science of Aging. Category: Cosmetic ingredients and additives. Synonyms: Hydroxypropyl tetrahydropyrantriol. Mexoryl SBB. Pro-xylane (pharmaceutical). CAS No. 439685-79-7. Product ID: CIA439685797. Molecular formula: C8H16O5. Mole weight: 192.21. SMILES: CC(CC1C(C(C(CO1)O)O)O)O. Appearance: White to off-white powder. Standard: In-house. | |
| Prucalopride Succinate | Prucalopride Succinate is the succinate salt form of prucalopride, an orally bioavailable dihydro-benzofuran-carboxamide and selective serotonin (5-HT4) receptor agonist, with gastrointestinal (GI) prokinetic activity. Category: Other apis. Synonyms: Resolor. Prucalopride Succinat. Prucalopride (succinate). CAS No. 179474-85-2. Product ID: API179474852. Molecular formula: C22H32ClN3O7. Mole weight: 486. EINECS: 680-639-5. SMILES: COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.C(CC(=O)O)C(=O)O. Appearance: White to off-white powder. Standard: In-house. | |
| Prulifloxacin | Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone antibiotic. It Inhibits bacterial DNA synthesis by inhibiting the activity of bacterial DNA topoisomerase II and IV. Category: Active pharmaceutical ingredients. CAS No. 123447-62-1. Product ID: API123447621. Molecular formula: C21H20FN3O6S. Mole weight: 461.46. | |
| PSI-6206 13C | PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1256490-42-2. Product ID: API1256490422. Molecular formula: C10H13FN2O5. Mole weight: 264.23. | |
| PSI-7409 | PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Category: Active pharmaceutical ingredients. CAS No. 1015073-42-3. Product ID: API1015073423. Molecular formula: C10H16FN2O14P3. Mole weight: 500.16. | |
| PSI-7409 tetrasodium | PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively. Category: Active pharmaceutical ingredients. CAS No. 1621884-22-7. Product ID: API1621884227. Molecular formula: C10H16FN2Na4O14P3. Mole weight: 592.117. | |
| Pyridostigmine Bromide | Pyridostigmine bromide is An inhibitor of ACE (acetylcholinesterase). Category: Active pharmaceutical ingredients. CAS No. 101-26-8. Product ID: API101268. Molecular formula: C9H13BrN2O2. Mole weight: 261.12. Appearance: Powder. | |
| Pyrithione Zinc | Pyrithione Zinc is a coordination complex of zinc with 1-hydroxy-2-pyridinethione (pyrithione). It is widely recognized for its broad-spectrum antifungal and antibacterial properties, and has been extensively characterized as an active ingredient in personal care applications. The compound contains a zinc center coordinated by two pyrithione ligands in a bidentate S,O-binding mode. Applications: Used in the treatment of seborrheic dermatitis, dandruff, and tinea versicolor. pyrithione zinc is a broad-spectrum antifungal and antibacterial agent widely incorporated into shampoos, soaps, and topical formulations. it is also applied in psoriasis management and as a preservative in personal care products. Category: Active pharmaceutical ingredients. Synonyms: Bis[(1-oxylatopyridinium-2-yl)thio]zinc;Bis[[(pyridine 1-oxide)-2-yl]thio] zinc salt. CAS No. 13463-41-7. Product ID: API13463417. Molecular formula: C10H8N2O2S2Zn. Mole weight: 317.7. EINECS: 236-671-3. InChIKey: OTPSWLRZXRHDNX-UHFFFAOYSA-L. Appearance: White to off-white solid. | |
| Pyrophosphatase, Inorganic GMP-grade | Inorganic Pyrophosphatase (PPase) is a highly active enzyme from a recombinant source in E. coli provided as a liquid reagent, manufactured under GMP process requirements and tested extensively for the absence of nucleases, alkaline phosphatase and other contaminants. PPase is an important biological catalyst because it has the unique ability to catalyze the hydrolysis of a high energy molecule. It is widely used as an auxiliary enzyme to improve the efficiency of many reactions in molecular biology and biotechnology. Applications: Ppase is used in applications where nucleic acid synthesis or amplification is prone to accumulation of pyrophosphate. the most common applications are in vitro transcription (ivt) processes and reverse transcription reactions, which show a significant increase in rna yield when ppase is used. ppase is also used routinely to improve the efficiency of dna replication, pcr, single-base extension reactions, dna sequencing, multiply-prime rolling circle amplification and some specialized enzymatic assays. Category: Biochemical reagents. Grades: DMF. Product ID: PIPB-0797. Standard: Facility GMP. | |
| Quazepam | Quazepam is a benzodiazepine derivative classified as a long-acting hypnotic agent. It is distinguished structurally by the presence of a trifluoroethyl group at the N-1 position and a 2-fluorophenyl substituent, features that contribute to its selective pharmacological profile among benzodiazepines. Applications: Used in the treatment of insomnia. quazepam is a long-acting benzodiazepine hypnotic indicated for the management of sleep-onset and sleep-maintenance difficulties. its unique active metabolite profile provides sustained hypnotic efficacy throughout the night with reduced risk of early-morning rebound insomnia. Category: Active pharmaceutical ingredients. Synonyms: Quazepamum;7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione. CAS No. 36735-22-5. Product ID: API36735225. Molecular formula: C17H11ClF4N2S. Mole weight: 386.8. InChIKey: IKMPWMZBZSAONZ-UHFFFAOYSA-N. Appearance: Solid. | |
| Quercetin | Quercetin has been used as an antioxidant which reversed the immunosuppressive effects of high glucose and hyperglycemic sera in type 2 diabetic patients. Category: Hypoglycemic apis. Synonyms: 3,3',4',5,7-Pentahydroxyflavone2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one;MELETIN;FLAVIN MELETIN;LABOTEST-BB LT00455149;CI NO 75670;XANTHAURINE;QUERCETINE;QUERTINE. CAS No. 117-39-5. Product ID: API117395. Molecular formula: C15H10O7. Mole weight: 302.24. EINECS: 204-187-1. InChIKey: REFJWTPEDVJJIY-UHFFFAOYSA-N. Appearance: solid. | |
| Quercetin dihydrate | Quercetin dihydrate used as a Inhibitor of protein tyrosine kinase, mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Category: Expectorant apis. Synonyms: QUERCETIN DIHYDRATE;3,5,7,3',4'-PENTAHYDROXYFLAVONE DIHYDRATE;3,3',4',5,7-pentahydroxy-flavondihydrate;Flavone,3,3',4',5,7-pentahydroxy-,dihydrate;2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE DIHYDRATE;3,3',4',5,7-PENTAHYDROXYFLAVONE 2H2O;3,3',4',5,7-PENTAHYDROXYFLAVONE DIHYDRATE;3,3',4',5,7-PENTAHYDROXYFLAVONE HYDRATE. CAS No. 6151-25-3. Product ID: API6151253. Molecular formula: C15H14O9. Mole weight: 338.27. EINECS: 612-158-3. InChIKey: GMGIWEZSKCNYSW-UHFFFAOYSA-N. Appearance: Yellow solid. | |
| Quinapril Hydrochloride | Quinapril hydrochloride is the hydrochloride salt of quinapril, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor prodrug. It appears as a white to off-white amorphous powder that is freely soluble in aqueous solvents and is formulated into oral tablets for once or twice daily administration. Applications: Quinapril hydrochloride is indicated for the treatment of hypertension, where it may be used alone or in combination with thiazide diuretics. it is also indicated as adjunctive therapy in the management of heart failure, typically administered concomitantly with diuretics and/or cardiac glycosides. dosing range for hypertension is 10-40 mg once daily, with twice daily dosing of 10-20 mg employed for heart failure management. Category: Antihypertensive apis. Synonyms: Quinapril HCl. CAS No. 82586-55-8. Product ID: API0232032. Molecular formula: C25H31ClN2O5. Mole weight: 475. EINECS: 620-479-5. InChIKey: IBBLRJGOOANPTQ-JKVLGAQCSA-N. Appearance: White crystalline powder. | |
| Quinidine Gluconate | Quinidine Gluconate is the gluconate salt of quinidine, a Class Ia antiarrhythmic agent derived from the bark of the cinchona tree. As a gluconate salt, it has greater solubility and is used in controlled-release oral formulations and intravenous infusions for the management of cardiac arrhythmias. It exerts multiple electrophysiological effects including sodium channel blockade and potassium channel modulation. Applications: Quinidine gluconate is indicated for the treatment and prevention of supraventricular arrhythmias (including atrial fibrillation and av nodal reentrant tachycardia) and ventricular arrhythmias (ventricular tachycardia, premature ventricular contractions). Category: Active pharmaceutical ingredients. CAS No. 7054-25-3. Product ID: API7054253. Molecular formula: C26H36N2O9. Mole weight: 520.6. EINECS: 230-333-9. InChIKey: XHKUDCCTVQUHJQ-LCYSNFERSA-N. | |
| Quorum Sensing-IN-2 | Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor that reduces bacterial pathogenicity without affecting growth, exhibits minimal hemolytic activity, effectively inhibits bacterial infections, and shows a synergistic effect when combined with Ciprofloxacin in a P. aeruginosa PAO1-infected bacteremia model. Category: Active pharmaceutical ingredients. CAS No. 2925926-80-1. Product ID: API2925926801. Molecular formula: C19H13F2NO3. Mole weight: 341.31. | |
| R-130823 | R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823 , with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively. Category: Active pharmaceutical ingredients. CAS No. 321344-32-5. Product ID: API321344325. Molecular formula: C28H26FN3. Mole weight: 423.52. | |
| (R)-(+)-2-Tetrahydrofuroie Acid | (R)-(+)-2-Tetrahydrofuroic acid can be used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs. Category: Other apis. Synonyms: (2R)-oxolane-2-carboxylic acid;(R)-(+)-Tetrahydrofuran-2-carboxylic Acid. CAS No. 87392-05-0. Product ID: API87392050. Molecular formula: C5H8O3. Mole weight: 116.12. EINECS: 627-523-2. Appearance: Clear liquid. | |
| R 50595 | R 50595 is a selective non-competitive cisapride antagonist. Category: Active pharmaceutical ingredients. CAS No. 104860-61-9. Product ID: API104860619. Molecular formula: C30H35Cl2F2N3O3. Mole weight: 594.52. | |
| rac Bendroflumethiazide-d5 | rac Bendroflumethiazide-d5 is a deuterated compound of rac Bendroflumethiazide. rac Bendroflumethiazide has a CAS number of 73-48-3. A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810). Category: Active pharmaceutical ingredients. CAS No. 1330183-13-5. Product ID: API1330183135. Molecular formula: C15H9D5F3N3O4S2. Mole weight: 426.45. | |
| Racecadotril | Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM. Category: Other apis. Synonyms: Acetorphan. Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate. Hidrasec. CAS No. 81110-73-8. Product ID: API81110738. Molecular formula: C21H23NO4S. Mole weight: 385.5. EINECS: 688-010-7. SMILES: CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2. Appearance: White Solid. Standard: EP CEP. | |
| Rac-Efavirenz | Rac-Efavirenz is a non stereospecific structure of Efavirenz. Category: Active pharmaceutical ingredients. Synonyms: L 741211. CAS No. 177530-93-7. Product ID: API177530937. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
| (Rac)-Nebivolol | (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol, a selective β1-adrenergic receptor antagonist (IC50 = 0.8 nM). Nebivolol exhibits vasodilatory activity and can prevent Nox2/NADPH oxidase up-regulation and lipoperoxidation in early stages of ethanol-induced cardiac toxicity. Category: Active pharmaceutical ingredients. CAS No. 99200-09-6. Product ID: API99200096. Molecular formula: C22H25F2NO4. Mole weight: 405.43. | |
| rac-Paroxetine-d4 Hydrochloride | rac-Paroxetine-d4 Hydrochloride is a deuterated compound of rac-Paroxetine Hydrochloride. rac-Paroxetine Hydrochloride has a CAS number of 78246-49-8. Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression. Category: Active pharmaceutical ingredients. CAS No. 1217683-35-6. Product ID: API1217683356. Molecular formula: C19H17D4ClFNO3. Mole weight: 369.85. | |
| rac-Sitagliptin-d4 HCl | rac-Sitagliptin-d4 HCl is a deuterated compound of rac-Sitagliptin HCl. Category: Active pharmaceutical ingredients. CAS No. 2749855-96-5. Product ID: API2749855965. Molecular formula: C16H12D4ClF6N5O. Mole weight: 447.8. | |
| (Rac)-Tezacaftor | (Rac)-Tezacaftor ((Rac)-VX-661) is a racemic mixture of the F508del CFTR corrector, Tezacaftor, used in cystic fibrosis research. Category: Active pharmaceutical ingredients. CAS No. 1226709-85-8. Product ID: API1226709858. Molecular formula: C26H27F3N2O6. Mole weight: 520.5. | |
| Radezolid | Radezolid (RX-1741) is a novel oxazolidinone antibiotic. Category: Active pharmaceutical ingredients. CAS No. 869884-78-6. Product ID: API869884786. Molecular formula: C22H23FN6O3. Mole weight: 438.45. | |
| RadotinibI | Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other tyrosine kinase Bcr-Abl inhibitors. Category: Active pharmaceutical ingredients. CAS No. 926037-48-1. Product ID: API926037481. Molecular formula: C27H21F3N8O. Mole weight: 530.5. | |
| (R)-Afatinib | (R)-Afatinib ((R)-BIBW 2992), an isomer of Afatinib, is a potent, orally administered, irreversible inhibitor targeting the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFR wt, 0.4 nM for EGFR L858R, 10 nM for EGFR L858R/T790M, and 14 nM for HER2, holding potential for research into esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer. Category: Active pharmaceutical ingredients. CAS No. 439081-17-1. Product ID: API439081171. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Raloxifene Hydrochloride | Raloxifene hydrochloride belongs to the class of selective estrogen receptor modulators (SERMs), offering mixed agonist and antagonist activity depending on the target tissue. It is structurally distinct from estrogen, designed to provide beneficial estrogenic effects on bone without stimulating breast or uterine tissue. Applications: Raloxifene is indicated for the prevention and treatment of postmenopausal osteoporosis, significantly reducing vertebral fracture risk. it is also approved for lowering invasive breast cancer risk in postmenopausal women with osteoporosis or at high risk for the disease. unlike bisphosphonates, it does not reduce non-vertebral fractures but offers the added benefit of favorable lipid effects. Category: Active pharmaceutical ingredients. Synonyms: Raloxifene HCl; Evista; Keoxifene hydrochloride; Optruma; Raloxifene Teva; LY156758. CAS No. 82640-04-8. Product ID: API0231575. Molecular formula: C28H28ClNO4S. Mole weight: 510. EINECS: 639-789-7. InChIKey: BKXVVCILCIUCLG-UHFFFAOYSA-N. Appearance: White to light yellow crystalline powder. | |
| Raltegravir | Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION. Category: Active pharmaceutical ingredients. Synonyms: MK-0518. CAS No. 518048-05-0. Product ID: API518048050. Molecular formula: C20H21FN6O5. Mole weight: 444.42. | |
| Raltegravir potassium | Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection. Category: Active pharmaceutical ingredients. CAS No. 871038-72-1. Product ID: API871038721. Molecular formula: C20H20FN6O5·K. Mole weight: 482.51. | |
| Raltegravir sodium | Raltegravir (MK 0518) sodium is a potent and orally active inhibitor of HIV integrase (IN). Category: Active pharmaceutical ingredients. CAS No. 1292804-07-9. Product ID: API1292804079. Molecular formula: C20H20FN6NaO5. Mole weight: 466.405. | |
| Ramatroban | Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis. It has been used in trials studying the treatment of Asthma. Category: Active pharmaceutical ingredients. CAS No. 116649-85-5. Product ID: API116649855. Molecular formula: C21H21FN2O4S. Mole weight: 416.47. | |
| Ranolazine | Ranolazine is an anti-ischemic agent which inhibits late sodium currents. Category: Active pharmaceutical ingredients. CAS No. 95635-55-5. Product ID: API95635555. Molecular formula: C24H33N3O4. Mole weight: 427.54. | |
| Rapacuronium Bromide | Rapacuronium Bromide is a non-depolarizing neuromuscular blocking agent of the aminosteroid class. It is structurally related to vecuronium but modified to achieve an ultra-short onset of action comparable to succinylcholine while maintaining the non-depolarizing mechanism. Applications: Used as a rapid-onset neuromuscular blocking agent for tracheal intubation and surgical procedures requiring brief muscle relaxation. rapacuronium bromide is an aminosteroid non-depolarizing agent modified to achieve onset times comparable to succinylcholine while maintaining the non-depolarizing mechanism. Category: Active pharmaceutical ingredients. Synonyms: Rapacuronium;[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-Chemicalbook2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate. CAS No. 156137-99-4. Product ID: API156137994. Molecular formula: C37H61BrN2O4. Mole weight: 677.8. InChIKey: LVQTUXZKLGXYIU-GWSNJHLMSA-M. Appearance: Yellow solid. | |
| Rasagiline Mesylate | Rasagiline Mesylate is a selective irreversible MAO-B inhibitor. Category: Active pharmaceutical ingredients. CAS No. 161735-79-1. Product ID: API161735791. Molecular formula: C13H17NO3S. Mole weight: 267.34. | |
| RaseglurantADX-10059 | Raseglurant (ADX-10059) is an mGlu5 negative allosteric modulator. It effectively counters migraines and alleviates haloperidol-induced catalepsy in mice. Category: Active pharmaceutical ingredients. CAS No. 757950-09-7. Product ID: API757950097. Molecular formula: C15H13FN2. Mole weight: 240.28. | |
| (R)-Bicalutamide | (R)-Bicalutamide is the R-type enantiomer of Bicalutamide, an androgen receptor (AR) antagonist that exhibits antitumour effects. (R)-Bicalutamide is widely used in prostate cancer research. Category: Active pharmaceutical ingredients. CAS No. 113299-40-4. Product ID: API113299404. Molecular formula: C18H14F4N2O4S. Mole weight: 430.37. | |
| (R)-Citalopram oxalate | (R)-Citalopram oxalate is a less active enantiomer of Escitalopram Oxalate. Escitalopram Oxalate is a potent and selective serotonin reuptake inhibitor. Category: Active pharmaceutical ingredients. CAS No. 219861-53-7. Product ID: API219861537. Molecular formula: C22H23FN2O5. Mole weight: 414.43. | |
| Rebamipide | Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer. Category: Inhibit gastric acid secretion apis. Synonyms: Proamipide. Mucosta. CAS No. 90098-04-7. Product ID: API90098047. Molecular formula: C19H15ClN2O4. Mole weight: 370.8. EINECS: 815-380-0. SMILES: C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC=C(C=C3)Cl. Appearance: White Solid. | |
| Reduced Haloperidol | Reduced haloperidol is an active metabolite of haloperidol. It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. Category: Active pharmaceutical ingredients. CAS No. 34104-67-1. Product ID: API34104671. Molecular formula: C21H25ClFNO2. Mole weight: 377.88. | |
| Refined Cottonseed Oil | Refined Cottonseed Oil. Category: Veterinary products. Synonyms: EINECS 232-280-7;MFCD00130872;Cottonseed Oil. CAS No. 8001-29-4. Product ID: Pro-8001294-USP. Molecular formula: CH4. Mole weight: 16.04246. Appearance: Yellow Oil. Standard: USP/NF, for injection. | |
| Regorafenib | Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity. Category: Active pharmaceutical ingredients. CAS No. 755037-03-7. Product ID: API755037037. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82. | |
| Regorafenib-d3 | Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase. Category: Active pharmaceutical ingredients. CAS No. 1255386-16-3. Product ID: API1255386163. Molecular formula: C21H15ClF4N4O3. Mole weight: 485.83. | |
| Regorafenib Hydrochloride | Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Category: Active pharmaceutical ingredients. Synonyms: BAY73-4506 hydrochloride. CAS No. 835621-07-3. Product ID: API835621073. Molecular formula: C21H16Cl2F4N4O3. Mole weight: 519.28. | |
| Regorafenib mesylate | Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor, inhibiting VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM), and Raf-1 (IC50: 2.5 nM), with potent anti-tumor and anti-angiogenic effects. Category: Active pharmaceutical ingredients. CAS No. 835621-08-4. Product ID: API835621084. Molecular formula: C22H19ClF4N4O6S. Mole weight: 578.92. | |
| Regorafénib N-oxyde (M2) | Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM). Category: Active pharmaceutical ingredients. CAS No. 835621-11-9. Product ID: API835621119. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.81. | |
| (R)-Elagolix | (R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. Category: Active pharmaceutical ingredients. CAS No. 834153-87-6. Product ID: API834153876. Molecular formula: C32H30F5N3O5. Mole weight: 631.59. | |
| (R)-Elexacaftor | (R)-Elexacaftor, an enantiomer of Elexacaftor, functions as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It exhibits an EC50 of 0.29 μM for the CFTR dF508 mutation. Category: Active pharmaceutical ingredients. Synonyms: (R)-VX-445. CAS No. 2229860-99-3. Product ID: API2229860993. Molecular formula: C26H34F3N7O4S. Mole weight: 597.65. | |
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