Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Remifentanil Hydrochloride | Remifentanil hydrochloride is the hydrochloride salt of remifentanil, a synthetic ultra-short-acting μ-opioid receptor agonist belonging to the 4-anilidopiperidine class of drugs, structurally related to fentanyl. First approved by the FDA in 1996, it is supplied as a sterile lyophilized powder for intravenous injection or infusion following reconstitution. Applications: Remifentanil is indicated for intravenous analgesia and anesthesia during general anesthesia induction and maintenance, as well as for monitored anesthesia care. it provides deeper intraoperative analgesia compared to other opioids, with faster recovery times, earlier extubation, and reduced need for naloxone reversal, though it is associated with higher postoperative analgesia requirements. its unique organ-independent metabolism makes it particularly useful in patients with hepatic or renal impairment, and it is well-tolerated in both adult and pediatric populations. Category: Anesthetic analgesia apis. Synonyms: Remifentanil HCl, GI 87084B, GI-87084B. CAS No. 132539-07-2. Product ID: API0232092. Molecular formula: C20H29ClN2O5. Mole weight: 412.9. EINECS: 638-766-9. InChIKey: WFBMIPUMYUHANP-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. |  |
| Repaglinide | Repaglinide is a non-sulfonylurea insulin releasing agent for the treatment of type 2 diabetes mellitus. Category: Active pharmaceutical ingredients. CAS No. 135062-02-1. Product ID: API135062021. Molecular formula: C27H36N2O4. Mole weight: 452.59. Standard: EP/CP. | |
| Repotrectinib | Repotrectinib has anti-cancer activity. Category: Active pharmaceutical ingredients. Synonyms: TPX-0005. CAS No. 1802220-02-5. Product ID: API1802220025. Molecular formula: C18H18FN5O2. Mole weight: 355.37. EINECS: 125-417-3. | |
| Resmetirom | Resmetirom is a novel, first-in-class, selective Thyroid Hormone Receptor-beta (THR-β) partial agonist and the first FDA-approved drug for the treatment of non-cirrhotic Metabolic Dysfunction-Associated Steatohepatitis (MASH), also referred to as NASH. As a significant advancement in the treatment of this complex chronic liver disease, Resmetirom addresses a critical unmet need by targeting the underlying pathology of MASH. Applications: Resmetirom is indicated for the treatment of adult patients with non-cirrhotic mash who have evidence of moderate to advanced liver fibrosis (f2 to f3 stage). its use can lead to a reduction of steatosis, or the pathological accumulation of fat in the liver, as well as associated metabolic abnormalities, such as high levels of serum cholesterol and triglycerides, in order to stop disease progression. Category: Cardiovascular and geriatric medicine apis. Synonyms: 2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile; MGL-3196; VIA-3196. CAS No. 920509-32-6. Product ID: API920509326. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.2. InChIKey: FDBYIYFVSAHJLY-UHFFFAOYSA-N. | |
| Resveratrol | Resveratrol can prevent the oxidation of low density lipoprotein, and has the potential effect on preventing cardiovascular disease, cancer, antivirus and immune regulation. Category: Anti-atherosclerotic apis. Synonyms: TRANS-3,4,5-TRIHYDROXYSTILBENE;TRANS-3,5,4'-STILBENETRIOL;TRANS-RESVERATROL;TRANS-1,2-(3,4',5-TRIHYDROXYDIPHENYL)ETHYLENE;RESVERATROL;RESVERATROLE;3,4',5'-TRIHYDROXY-TRANS-STILBENE;3,4',5-TRIHYDROXY-TRANS-STILBENE. CAS No. 501-36-0. Product ID: API501360. Molecular formula: C14H12O3. Mole weight: 228.24. EINECS: 610-504-8. SMILES: C1(O)=CC(/C=C/C2=CC=C(O)C=C2)=CC(O)=C1. InChIKey: LUKBXSAWLPMMSZ-OWOJBTEDSA-N. Appearance: Powder. | |
| Retatrutide | Retatrutide is a 39-amino acid peptide engineered based on the GIP peptide backbone, functioning as a novel triple-agonist peptide targeting the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Through its triple-agonist action, Retatrutide may demonstrate groundbreaking therapeutic efficacy. Category: Active pharmaceutical ingredients. Synonyms: LY3437943;GIPR/GLP-1R. Grades: USDMF. CAS No. 2381089-83-2. Product ID: API2381089832. Molecular formula: C221H342N46O68. Mole weight: 4731.33. EINECS: 200-001-8. Appearance: White lyophilized powder. Standard: Facility GMP. | |
| Revaprazan | Revaprazan is a novel, selective potassium-competitive acid blocker, to be specific, it reversibly inhibits gastric H(+)/K(+)-ATPase and shows effective acid suppression comparable to PPIs. Category: Active pharmaceutical ingredients. Synonyms: SB-641257. CAS No. 199463-33-7. Product ID: API199463337. Molecular formula: C22H23FN4. Mole weight: 362.44. | |
| Revaprazan hydrochloride | Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Category: Active pharmaceutical ingredients. CAS No. 178307-42-1. Product ID: API178307421. Molecular formula: C22H24ClFN4. Mole weight: 398.9. | |
| Revumenib | Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias. Category: Active pharmaceutical ingredients. Synonyms: SNDX-5613. CAS No. 2169919-21-3. Product ID: API2169919213. Molecular formula: C32H47FN6O4S. Mole weight: 630.82. Appearance: Solid. | |
| Rezafungin acetate | Rezafungin acetate. Applications: Antifungal & anti-infection. Category: Antibacterial apis. Synonyms: Biafungin acetate;CD101 acetate;Rezafungin acetate. CAS No. 1631754-41-0. Product ID: API1631754410. Molecular formula: C65H88N8O19. Mole weight: 1285.46. | |
| R-(-)-Flecainide | R-(-)-Flecainide is a orally active antiarrhythmic agent that inhibits ventricular ectopic activity. Category: Active pharmaceutical ingredients. CAS No. 99495-90-6. Product ID: API99495906. Molecular formula: C17H20F6N2O3. Mole weight: 414.34. | |
| riboflavin (vitamin B2) | riboflavin (vitamin B2). Category: Veterinary products. Synonyms: 6,7-dimethyl-9-D-ribitylisoalloxazine;riboflavine;D-Ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-;Flavin BB;Hibon;1-Deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)-D-ribitol;D-Ribitol, 1-deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)-;Russupteridine Yellow III;VITAMIN B2;(-)-Riboflavin;Lactoflavin;Riboflavin (B2);Beflavin;MFCD00005022;BEFLAVINE;1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol;EINECS 201-507-1;1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol;riboflavin;EINECS 201-507-1. CAS No. 83-88-5. Product ID: PIVF-0044. Molecular formula: C17H20N4O6. Mole weight: 376.364. Appearance: Yellow to orange/yellow crystalline powder. | |
| Rifampin | Rifampin, also known as rifampicin, is a bactericidal antibiotic belonging to the rifamycin class, available for oral administration as capsules containing 150 mg or 300 mg of the active ingredient. Applications: Rifampin is indicated as a frontline agent for all forms of tuberculosis, always in combination with other active drugs to prevent emergence of resistant strains. it is also used in combination therapy for leprosy, for prophylaxis of meningococcal meningitis in asymptomatic carriers, and for serious staphylococcal infections and brucellosis. Category: Antibacterial apis. Synonyms: Rifampicin, Rifaldazine. CAS No. 13292-46-1. Product ID: API0232875. Molecular formula: C43H58N4O12. Mole weight: 822.94. EINECS: 236-312-0. InChIKey: JQXXHWHPUNPDRT-WLSIYKJHSA-N. | |
| Rifapentine | Rifapentine is a cyclopentyl rifamycin derivative and an antimycobacterial antibiotic. Initially FDA-approved in 1998, it is supplied as film-coated tablets for oral administration. Rifapentine is a potent, bactericidal agent with a very broad spectrum of activity, but its clinical use is primarily restricted to the treatment of mycobacterial infections to prevent the rapid emergence of resistant bacteria. Applications: Rifapentine is indicated for the treatment of active pulmonary tuberculosis in patients 12 years and older, always as part of a combination regimen. it is also indicated for the treatment of latent tuberculosis infection in patients 2 years and older, specifically in a 12-week once-weekly regimen of directly observed therapy in combination with isoniazid (3hp). Category: Antibacterial apis. Synonyms: Priftin, Rifapentin, Cyclopentylrifampicin. CAS No. 61379-65-5. Product ID: API0232427. Molecular formula: C47H64N4O12. Mole weight: 877. EINECS: 262-743-9. InChIKey: WDZCUPBHRAEYDL-GZAUEHORSA-N. | |
| Riluzole | Riluzole is a benzothiazole compound approved by the FDA in 1995 as the first disease-modifying therapy for amyotrophic lateral sclerosis (ALS). It carries orphan drug designation and remains the only medication proven to extend survival in ALS patients. Applications: Riluzole is indicated to extend life or delay the time to mechanical ventilation in patients with amyotrophic lateral sclerosis. the recommended dosage is 50 mg orally twice daily, taken at least one hour before or two hours after meals to optimize absorption. Category: Fluorine-containing apis. Synonyms: Rilutek, 2-Amino-6-(trifluoromethoxy)benzothiazole. CAS No. 1744-22-5. Product ID: API0233280. Molecular formula: C8H5F3N2OS. Mole weight: 234.2. EINECS: 605-724-6. InChIKey: FTALBRSUTCGOEG-UHFFFAOYSA-N. Appearance: White to faint yellow powder. | |
| Riluzole hydrochloride | Riluzole hydrochloride (PK 26124 hydrochloride) is an anticonvulsant compound belonging to the family of sodium channel blockers that inhibits GABA uptake.Riluzole hydrochloride is a sodium-glutamate antagonist with anticancer and neuroprotective activity and can be used to study amyotrophic lateral sclerosis and neurological disorders. Category: Active pharmaceutical ingredients. CAS No. 850608-87-6. Product ID: API850608876. Molecular formula: C8H6ClF3N2OS. Mole weight: 270.66. | |
| rimantadine hydrochloride | Rimantadine hydrochloride is an antiviral compound. Used for Influenza. Category: Active pharmaceutical ingredients. CAS No. 1501-84-4. Product ID: API1501844. Molecular formula: C12H22ClN. Mole weight: 215.763. Appearance: Crystalline. | |
| Rimegepant | Rimegepant is a highly potent and selective oral antagonist of the calcitonin gene-related peptide (CGRP) receptor. It represents a novel class of migraine therapy that targets the underlying pathophysiology of the condition. Applications: Rimegepant is used for the acute treatment of migraine with or without aura in adults, and for the prevention of episodic migraine in adult patients. it is the first cgrp receptor antagonist with proven efficacy in both prevention and acute treatment. Category: Fluorine-containing apis. Synonyms: BMS 927711. CAS No. 1289023-67-1. Product ID: API1289023671. Molecular formula: C28H28F2N6O3. Mole weight: 534.56. InChIKey: KRNAOFGYEFKHPB-ANJVHQHFSA-N. Appearance: White to off-white powder. | |
| Rimegepant sulfate hydrate | Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile. Category: Active pharmaceutical ingredients. CAS No. 1374024-48-2. Product ID: API1374024482. Molecular formula: C56H64F4N12O13S. Mole weight: 1221.2526. | |
| Rimexolone | Rimexolone is a synthetic glucocorticoid with high receptor affinity, developed specifically for ophthalmic use. Its unique structure a 16α-methyl, 17α-propyl, and 21-nor configuration confers potent anti-inflammatory activity in ocular tissues while promoting rapid systemic metabolism, minimizing systemic glucocorticoid exposure. Applications: Indicated for the treatment of ocular inflammation including postoperative anterior uveitis and conjunctivitis. rimexolone is a glucocorticoid specifically developed for ophthalmic use with a unique 21-nor steroid structure that provides potent local anti-inflammatory activity while promoting rapid systemic metabolism to minimize hpa axis suppression. Category: Active pharmaceutical ingredients. Synonyms: (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one. CAS No. 49697-38-3. Product ID: API49697383. Molecular formula: C24H34O3. Mole weight: 370.5. InChIKey: QTTRZHGPGKRAFB-OOKHYKNYSA-N. | |
| Riociguat-13C-d6 | Riociguat-13C-d6 is the 13C and deuterated compound of Riociguat. Riociguat has a CAS number of 625115-55-1. Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension. Category: Active pharmaceutical ingredients. CAS No. 1304478-43-0. Product ID: API1304478430. Molecular formula: C20H13D6FN8O2. Mole weight: 428.45. | |
| Ripretinib | Ripretinib (DCC-2618) is an orally bioavailable inhibitor of (KIT) and (PDGFRA). Category: Active pharmaceutical ingredients. CAS No. 1442472-39-0. Product ID: API1442472390. Molecular formula: C24H21BrFN5O2. Mole weight: 510.36. | |
| Risperidone | Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. Category: Active pharmaceutical ingredients. Synonyms: Risperidal, R 64 766. CAS No. 106266-06-2. Product ID: API106266062. Molecular formula: C23H27FN4O2. Mole weight: 410.48. | |
| Risperidone-d4 | Risperidone-d4, a deuterium-labeled version of Risperidone, acts as a potent antagonist of the dopamine D2 and serotonin 5-HT2 receptors, and inhibits P-Glycoprotein, displaying Ki values of 5.9 nM and 4.8 nM for the dopamine D2 and 5-HT2A receptors, respectively. Category: Active pharmaceutical ingredients. CAS No. 1020719-76-9. Product ID: API1020719769. Molecular formula: C23H23D4FN4O2. Mole weight: 414.51. | |
| Risperidone E-oxime | Risperidone E-oxime is an impurity of Risperidone, a serotonin 5-HT2 receptor blocker, P-glycoprotein inhibitor, and potent dopamine D2 receptor antagonist (Kis of 4.8 and 5.9 nM for 5-HT2A and dopamine D2 receptors, respectively). Category: Active pharmaceutical ingredients. CAS No. 691007-09-7. Product ID: API691007097. Molecular formula: C23H28F2N4O2. Mole weight: 430.49. | |
| Risperidone hydrochloride | Risperidone hydrochloride (R 64 766 hydrochloride) is a 5-HT2 receptor blocker, P-glycoprotein inhibitor, and dopamine D2 receptor antagonist, with activity on 5-HT2A (Ki: 4.8 nM) and dopamine D2 (Ki: 5.9 nM) receptors. Category: Active pharmaceutical ingredients. CAS No. 666179-74-4. Product ID: API666179744. Molecular formula: C23H28ClFN4O2. Mole weight: 446.95. | |
| Risperidone Mesylate | Risperidone Mesylate is a selective serotonin 5-HT2 receptor and dopamine D2 receptor blocker. Category: Active pharmaceutical ingredients. CAS No. 666179-96-0. Product ID: API666179960. Molecular formula: C24H31FN4O5S. Mole weight: 506.59. | |
| (R)-Larotrectinib | (R)-Larotrectinib is a potent TRK inhibitor, targeting TrkA with an IC50 value of 28.5 nM. (R)-Larotrectinib can be utilized to study cancer, inflammation, and certain infectious diseases. Category: Active pharmaceutical ingredients. CAS No. 1223404-68-9. Product ID: API1223404689. Molecular formula: C21H22F2N6O2. Mole weight: 428.44. | |
| (R)-Linezolid | (R)-Linezolid, an impurity of Linezolid, inhibits the initiation of bacterial protein synthesis. Category: Active pharmaceutical ingredients. CAS No. 872992-20-6. Product ID: API872992206. Molecular formula: C16H20FN3O4. Mole weight: 337.35. | |
| Ro 19-7728 | Ro 19-7728 is a metabolite of fleroxacin. Category: Active pharmaceutical ingredients. CAS No. 104638-13-3. Product ID: API104638133. Molecular formula: C17H18F3N3O4. Mole weight: 385.343. | |
| Ro-23-9424 | Ro-23-9424 is a dual-action cephalosporin with a fleroxacin esterified at the 3' position andaminothiazolylmethoxyimino-type side chain at the 7 position. Ro-23-9424 has broad and potent antibacterial activity in vitro and in vivo. Category: Active pharmaceutical ingredients. CAS No. 115622-58-7. Product ID: API115622587. Molecular formula: C31H31F3N8O8S2. Mole weight: 764.75. | |
| Ro 24-6392 | Ro 24-6392 is an ester-linked co-drug combining ciprofloxacin and desacetylcefotaxime. Ro 24-6392 demonstrats activity against a wide spectrum of aerobic bacteria. Category: Active pharmaceutical ingredients. CAS No. 131149-63-8. Product ID: API131149638. Molecular formula: C31H31FN8O8S2. Mole weight: 726.76. | |
| Roflumilast | Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Category: Active pharmaceutical ingredients. CAS No. 162401-32-3. Product ID: API162401323. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.21. | |
| Roflumilast Impurity E | Roflumilast Impurity E is an impurity of Roflumilast, which acts as a selective and long-acting enzyme PDE-4 inhibitor (IC50 value of 0.8 nM). Category: Active pharmaceutical ingredients. CAS No. 1391052-76-8. Product ID: API1391052768. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. | |
| Roflumilast N-oxide | Roflumilast N-oxide is an inhibitor of PDE type 4. Category: Active pharmaceutical ingredients. CAS No. 292135-78-5. Product ID: API292135785. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflurane | Roflurane is a halocarbon drug. It has been investigated as an inhalational anesthetic. Category: Active pharmaceutical ingredients. Synonyms: DA-893. CAS No. 679-90-3. Product ID: API679903. Molecular formula: C3H4BrF3O. Mole weight: 192.96. | |
| Rolapitant | Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 552292-08-7. Product ID: API552292087. Molecular formula: C25H26F6N2O2. Mole weight: 500.48. | |
| Rolapitant hydrochloride | Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models. Category: Active pharmaceutical ingredients. CAS No. 858102-79-1. Product ID: API858102791. Molecular formula: C25H27ClF6N2O2. Mole weight: 536.94. | |
| Rolapitant hydrochloride hydrate | Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 914462-92-3. Product ID: API914462923. Molecular formula: C25H29ClF6N2O3. Mole weight: 554.95. | |
| Ropinirole Hydrochloride | Ropinirole Hydrochloride is a non-ergot dopamine D2/D3 receptor agonist used for the treatment of Parkinson's disease and Restless Legs Syndrome (RLS). Its chemical structure is distinct from ergot derivatives such as bromocriptine and cabergoline, eliminating the risk of ergot-related cardiac valvulopathy. It demonstrates preferential binding to D3 receptors, which are highly expressed in the mesolimbic and nigrostriatal dopaminergic pathways. Applications: Ropinirole hydrochloride is indicated as monotherapy for early-stage parkinson's disease and as adjunctive therapy to levodopa in advanced disease. it is also indicated for the treatment of moderate to severe restless legs syndrome. Category: Active pharmaceutical ingredients. Synonyms: 4-[2-(Di-n-propylamino)ethyl]-2(3H)-indolone Hydrochloride;4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one Hydrochloride. CAS No. 91374-20-8. Product ID: API91374208. Molecular formula: C16H25ClN2O. Mole weight: 296.83. EINECS: 635-615-9. InChIKey: XDXHAEQXIBQUEZ-UHFFFAOYSA-N. Appearance: Pale yellow powder. | |
| Ropivacaine Hydrochloride | Ropivacaine hydrochloride is the hydrochloride salt of ropivacaine, a long-acting amide-type local anesthetic approved by the FDA in 1996 for surgical anesthesia and acute pain management. It is chemically related to bupivacaine but is formulated as the pure S-enantiomer to enhance its safety profile. Applications: Ropivacaine hydrochloride is indicated for epidural blocks including cesarean section, major nerve blocks, local infiltration, and continuous epidural infusion for postoperative or labor pain management. lower concentrations (0.2%) provide analgesia with minimal motor block, while higher concentrations (0.5-1%) produce complete surgical anesthesia with motor blockade. compared to bupivacaine, ropivacaine offers faster regression of sensory and motor blockade, potentially facilitating earlier mobilization, and is associated with reduced incidence of hypotension and cardiotoxicity. Category: Anesthetic analgesia apis. Synonyms: ROPIVACAINE HCl, Ropivacaine monohydrochloride, DTXSID2048379. CAS No. 98717-15-8. Product ID: API0232524. Molecular formula: C17H27ClN2O. Mole weight: 310.86. EINECS: 663-286-1. InChIKey: NDNSIBYYUOEUSV-RSAXXLAASA-N. | |
| Rosuvastatin | Rosuvastatin is a competitive inhibitor of HMG-CoA reductase. Category: Active pharmaceutical ingredients. CAS No. 287714-41-4. Product ID: API287714414. Molecular formula: C22H28FN3O6S. Mole weight: 481.54. | |
| Rosuvastatin calcium | Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity. Category: Active pharmaceutical ingredients. CAS No. 147098-20-2. Product ID: API147098202. Molecular formula: 2(C22H27FN3O6S)Ca. Mole weight: 1001.14. | |
| Roxadustat | Roxadustat. Category: Active pharmaceutical ingredients. Synonyms: 2-(4-hydroxy-1-Methyl-7-phenoxyisoquinoline-3-carboxaMido)acetic acid;2-(4-HYDROXY-1-METHYL-7-PHENOXYISOQUINOLINE-3-CARBOXAMIDO)ACETIC ACID;[[(4-Hydroxy-1-Methyl-7-phenoxyisoquinolin-3-yl)carbonyl]aMino]acetic Acid;N-[(4-Hydroxy-1-Methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine;FG-4592/FG4592;Glycine, N-[(4-hydroxy-1-Methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-;FG-4592(ASP1517). CAS No. 808118-40-3. Product ID: API808118403. Molecular formula: C19H16N2O5. Mole weight: 352.34. EINECS: 813-400-2. Appearance: solid. Standard: DMF in preparation. | |
| (R)-Tegoprazan | (R)-Tegoprazan, a benzimidazole derivative, serves as a potent inhibitor of kidney H+/K+-ATPase, demonstrating significant efficacy with an IC50 of 98 nM against canine kidney Na+/K+-ATPase. This compound shows promise for research in gastrointestinal diseases. Category: Active pharmaceutical ingredients. CAS No. 942195-56-4. Product ID: API942195564. Molecular formula: C20H19F2N3O3. Mole weight: 387.38. | |
| R-Thioctic acid Tromethamine | used in preparation of Piperazine Dithioctate for treatment of diabetic multiple neuritis, obesity. Category: Active pharmaceutical ingredients. CAS No. 137314-40-0. Product ID: API137314400. Molecular formula: C12H25NO5S2. Mole weight: 327.461. | |
| Rucaparib | Rucaparib (PF-01367338) is a PARP protein inhibitor (PARP-1 Ki=1.4 nM) and hexose hexose-6-phosphate dehydrogenase (H6PD) inhibitor with oral activity. Rucaparib exhibits antitumor activity, with activity against desmoplasia-resistant prostate cancer (CRPC). Category: Active pharmaceutical ingredients. CAS No. 283173-50-2. Product ID: API283173502. Molecular formula: C19H18FN3O. Mole weight: 323.36. | |
| Rucaparib acetate | Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC). Category: Active pharmaceutical ingredients. CAS No. 773059-23-7. Product ID: API773059237. Molecular formula: C21H22FN3O3. Mole weight: 383.423. | |
| Rucaparib camsylate | Rucaparib (AG014699) camsylate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) with a Ki=1.4 nM for PARP-1, and also inhibits hexose hexaphosphate dehydrogenase (H6PD). Rucaparib camsylate has potential for investigation in debulking resistant prostate cancer (CRPC) studies. Category: Active pharmaceutical ingredients. CAS No. 1327258-57-0. Product ID: API1327258570. Molecular formula: C19H18FN3O.xC10H16O4S. | |
| Rucaparib hydrochloride | Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD). This compound shows potential in research for castration-resistant prostate cancer (CRPC). Category: Active pharmaceutical ingredients. CAS No. 773059-19-1. Product ID: API773059191. Molecular formula: C19H19ClFN3O. Mole weight: 359.83. | |
| Rucaparib monocamsylate | Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains. Category: Active pharmaceutical ingredients. Synonyms: Rucaparib Camsylate. CAS No. 1859053-21-6. Product ID: API1859053216. Molecular formula: C29H34FN3O5S. Mole weight: 555.66. | |
| Rucaparib Phosphate | Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy. Category: Active pharmaceutical ingredients. CAS No. 459868-92-9. Product ID: API459868929. Molecular formula: C19H18FN3O·H3PO4. Mole weight: 421.36. | |
| Rucaparib tartrate | Rucaparib (AG014699) tartrate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2, and PARP-3) and acts on PARP-1 (Ki: 1.4 nM). It is also a hexose hexaphosphate dehydrogenase (H6PD) inhibitor and has potential for use in the study of destructive resistant prostate cancer (CRPC). Category: Active pharmaceutical ingredients. CAS No. 773059-22-6. Product ID: API773059226. Molecular formula: C23H24FN3O7. Mole weight: 473.457. | |
| Rufinamide | Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders. Category: Active pharmaceutical ingredients. CAS No. 106308-44-5. Product ID: API106308445. Molecular formula: C10H8F2N4O. Mole weight: 238.19. | |
| Rufloxacin | Rufloxacin is a drug that belongs to the class of fluoroquinolones, which act mainly as specific inhibitors of bacterial Topoisomerase II. These drugs involve in various diseases including cutaneous reactions, aging, etc. Category: Active pharmaceutical ingredients. Synonyms: MF 934. CAS No. 101363-10-4. Product ID: API101363104. Molecular formula: C17H18FN3O3S. Mole weight: 363.41. | |
| Rufloxacin hydrochloride | Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial that inhibits topoisomerase and B-cell differentiation in human mononuclear cells. Category: Active pharmaceutical ingredients. CAS No. 106017-08-7. Product ID: API106017087. Molecular formula: C17H19ClFN3O3S. Mole weight: 399.867. | |
| Sacubitril sodium | Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19. Category: Active pharmaceutical ingredients. CAS No. 149690-05-1. Product ID: API149690051. Molecular formula: C24H28NNaO5. Mole weight: 433.473. | |
| Sacubitril Valsartan Sodium | Sacubitril valsartan sodium is an angiotensin receptor-neprilysin inhibitor (ARNi) for the treatment of high blood pressure and heart failure. Category: Active pharmaceutical ingredients. CAS No. 936623-90-4. Product ID: API936623904. Molecular formula: C48H58N6O8. Mole weight: 847.03. Standard: In House. | |
| S-Adenosyl-L-methionine | S-Adenosyl-L-methionine. Category: Natural extract. Synonyms: ADEMETIONINE;S-ADENOSYL-L-METHIONINE;SAM-E;adenosine,5-((l-3-amino-3-carboxypropyl)methylsulfonio)-5-deoxy-,hydroxide,;adenosylmethionine;methioninyladenylate;p-Toluenesulfonate salt;ADEMETHIOINEDISULFATETOSYLATE. CAS No. 29908-03-0. Product ID: PIPE-0351. Molecular formula: C15H22N6O5S. Mole weight: 398.44. EINECS: 249-946-8. SMILES: O[C@@H]1[C@@H]([C@@H](C[S+](C)CC[C@H](N)C(=O)[O-])O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,9,15,r|. InChIKey: MEFKEPWMEQBLKI-WGIZDKKNNA-N. Appearance: Solid. Standard: USP. | |
| (S)-Afatinib | (S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, EGFR (L858R), EGFR (L858R/T790M), HER2, and HER4, respectively. Category: Active pharmaceutical ingredients. CAS No. 439081-18-2. Product ID: API439081182. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Safinamide | Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson's disease, restless leg syndrome and epilepsy. Category: Active pharmaceutical ingredients. Synonyms: FCE-26743, EMD1195686, EMD 1195686. CAS No. 133865-89-1. Product ID: API133865891. Molecular formula: C17H19FN2O2. Mole weight: 302.34. | |
| Salmon Calcitonin | Calcitonin, Salmon is a calcium regulating hormone which exhibits hypocalcaemic and hypophosphatemic properties. Category: Active pharmaceutical ingredients. CAS No. 47931-85-1. Product ID: API47931851. Molecular formula: C145H240N44O48S2. Mole weight: 3431.88. Appearance: Powder. | |
| Salt Active UltraNuclease GMP-grade | UltraNuclease is a recombinant, high-purity endonuclease, which is manufactured in GMP facilities and produced without animal-derived or antibiotic components. UltraNuclease is exclusively a Salt Active Nuclease, and designed to function optimally in high salt concentrations. These characteristics, combined with its overall high salt tolerance, make UltraNuclease suitable for laboratory research as well as high containment to large scale biomanufacturing that require high stringency and control of host nucleic acid residues. Applications: Ultranuclease is utilized for the purification of viral vaccines, viral vectors, and oncolytic viruses, as well as protein and polysaccharide pharmaceuticals. it is also used more broadly to reduce solution viscosity in cell supernatants and lysates, which results in an overall improvement in protein purification yields, and for sample preparation of analytical methods such as electrophoresis and chromatography. Category: Biochemical reagents. Grades: DMF. Product ID: PIPB-0801. Mole weight: 26.5 kDa. Standard: Facility GMP. | |
| Sapropterin | It has a role as a coenzyme, a diagnostic agent, a human metabolite and a cofactor. Category: Active pharmaceutical ingredients. Synonyms: tetrahydrobiopterin. R-THBP. Dapropterin. CAS No. 62989-33-7. Product ID: API62989337. Molecular formula: C9H15N5O3. Mole weight: 241.25. EINECS: 636-312-4. SMILES: CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O. Appearance: Solid. | |
| Saquinavir | Saquinavir was the first protease inhibitor approved for the treatment of HIV infection, introduced in 1995 as a breakthrough therapy. The drug is chemically a peptidomimetic that mimics the transition state of the viral protease substrate. Applications: Saquinavir is indicated in combination with ritonavir (as a pharmacokinetic booster) and other antiretrovirals for the treatment of hiv-1 infection. ritonavir dramatically increases saquinavir exposure by inhibiting cyp3a4 metabolism. due to its high pill burden and gastrointestinal side effects, it is no longer a first-line agent, though it remains a valuable option for treatment-experienced patients with resistance to newer protease inhibitors. Category: Active pharmaceutical ingredients. Synonyms: Fortovase; Saquinavirum; L3JE09KZ2F; CHEBI:63621; SCH-52852; DTXSID6044012. CAS No. 127779-20-8. Product ID: API0231588. Molecular formula: C38H50N6O5. Mole weight: 670.8. InChIKey: QWAXKHKRTORLEM-UGJKXSETSA-N. Appearance: White to off-white powder. | |
| Sch 58053 | Sch 58053 is an analog of Ezetimibe and a selective inhibitor of lymphatic cholesterol transport in the intestine. Category: Active pharmaceutical ingredients. CAS No. 194423-53-5. Product ID: API194423535. Molecular formula: C26H23ClFNO3. Mole weight: 451.92. | |
| Sclerotium Gum | Sclerotium Gum is a water soluble, nature-derived polysaccharide producedby fermentation of the filamentous fungus Sclerotium rolfsii. It is a highlyversatile ingredient, which improves the sensory characteristic of personalcare products. Scleroglucan has rheological properties, and unlike mostnatural and synthetic gums, has high thermal stability, is resistant tohydrolysis and retains skin moisture. Applications: Moisturizing, skin feel. Category: Cosmetic ingredients and additives. Synonyms: Scleroglucan polysaccharide;SCLEROTIUM GUM;Sclerotium Gum/Gigagum;Scleroglucan (Technical Grade);SCLEROGLUCAN,Sclerotium Gum,HYDROLYZED SCLEROTIUM GUM,Scleroglucan polysaccharide. CAS No. 39464-87-4. Product ID: CIA39464874. Molecular formula: C24H40O20. EINECS: 254-464-6. Appearance: Solid. | |
| (S)-crizotinibent-crizotinib | (S)-crizotinib (ent-crizotinib) (IC50 of 72 nM) , an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. Category: Active pharmaceutical ingredients. CAS No. 1374356-45-2. Product ID: API1374356452. Molecular formula: C21H22Cl2FN5O. Mole weight: 450.34. | |
| Sea Cucumber Peptide | Sea cucumber peptides are derived from sea cucumbers by controlled enzymatic hydrolysis. Essentially, the larger proteins contained in sea cucumbers are broken down into short chains of amino acids known as peptides. Sea cucumber peptides have a low molecular weight, are highly bioavailable, and can be absorbed by the human body more easily than proteins can. SCPs are jam-packed with collagen, taurine and minerals found in sea cucumbers. Applications: Because sea cucumber peptides have been shown to have many biological activities they have found many uses in nutraceutical and cosmetic products. sea cucumber peptides are commonly used indietary supplements to promote joint health, muscle recovery and maintenance and regulate metabolism such as inflammation or tiredness. as cosmetics, sea cucumber peptides are often marketed as "anti-aging" due to their skin-repairing properties that induce collagen production. they are commonly added to premium creams and serums to increase skin firmness and hydration. Category: Natural extract. Product ID: PIPE-0224. Standard: In-House. | |
| Sebacic Acid | Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It has a role as a human metabolite and a plant metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is a conjugate acid of a sebacate(2-) and a sebacate. It derives from a hydride of a decane. Category: Solvents. Synonyms: DECANEDIOIC ACID. 1,8-Octanedicarboxylic acid. 1,10-Decanedioic acid. CAS No. 111-20-6. Product ID: CHE111206. Molecular formula: C10H18O4. Mole weight: 202.25. EINECS: 203-845-5. SMILES: C(CCCCC(=O)O)CCCC(=O)O. Appearance: white granular powder. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.