Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Tiaprost | Tiaprost. Category: Active pharmaceutical ingredients. Synonyms: Iliren. 5-Heptenoic acid,7-[3,5-dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-. (E)-7-[3,5-dihydroxy-2-[(E)-3-hydroxy-4-thiophen-3-yloxybut-1-enyl]cyclopentyl]hept-5-enoic acid. CAS No. 71116-82-0. Product ID: API71116820. Molecular formula: C20H28O6S. Mole weight: 396.5. SMILES: C1C(C(C(C1O)C=CC(COC2=CSC=C2)O)CC=CCCCC(=O)O)O. |  |
| Ticagrelor | Ticagrelor (AR-C 126532XX), produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European Union by the European Commission on December 3, 2010, and by the US FDA on July 20, 2011. Its trade names are Brilinta (US), Brilique(EU) and Possia(EU). Category: Active pharmaceutical ingredients. Synonyms: AR-C 126532XX, AZD6140. CAS No. 274693-27-5. Product ID: API274693275. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57. | |
| Ticagrelor-d7 | Ticagrelor-d7 is a deuterated compound of Ticagrelor. Ticagrelor has a CAS number of 274693-27-5. Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European Union by the European Commission on December 3, 2010, and by the US FDA on July 20, 2011. Its trade names are Brilinta (US), Brilique(EU) and Possia(EU). Category: Active pharmaceutical ingredients. CAS No. 1265911-55-4. Product ID: API1265911554. Molecular formula: C23H21D7F2N6O4S. Mole weight: 529.61. | |
| Tildipirosin | Tildipirosin is a veterinary antibiotic. Category: Antibacterial apis. Synonyms: Zuprevo. UNII-S795AT66JB. S795AT66JB. CAS No. 328898-40-4. Product ID: API328898404. Molecular formula: C41H71N3O8. Mole weight: 734. EINECS: 640-368-5. SMILES: CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CCCCC3)C)C)CN4CCCCC4. Appearance: White Solid. Standard: Company Standard. | |
| Tiludronate Disodium | Tiludronate Disodium is a bisphosphonate inhibitor of bone resorption used for the treatment of Paget's disease of bone (osteitis deformans) and hypercalcemia of malignancy. Its molecular structure features a chloro-thienyl side chain attached to the bisphosphonate backbone, which confers moderate potency and a distinct binding profile to bone mineral compared to other bisphosphonates. Applications: Tiludronate disodium is indicated for the treatment of paget's disease of bone, where it normalizes elevated bone turnover markers and reduces bone pain, deformity, and fracture risk. Category: Active pharmaceutical ingredients. Synonyms: Tiludronic acid disodium salt. CAS No. 149845-07-8. Product ID: API149845078. Molecular formula: C7H7ClNa2O6P2S. Mole weight: 362.57. InChIKey: SKUHWSDHMJMHIW-UHFFFAOYSA-L. | |
| Timiperone | Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior. It is utilized in the research of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 57648-21-2. Product ID: API57648212. Molecular formula: C22H24FN3OS. Mole weight: 397.51. | |
| Timolol maleate | Timolol Maleate is a adrenergic receptor antagonist selective for β1-AR. Adrenergic receptors, or adrenoreceptors, are G-protein coupled receptors involved in a variety of sympathetic nervous system processes. Antagonists such as Timolol Maleate that affect the β adrenoreceptors are commonly known as beta blockers that decrease cardiac output. Category: Active pharmaceutical ingredients. CAS No. 26921-17-5. Product ID: API26921175. Molecular formula: C17H28N4O7S. Mole weight: 432.492. Appearance: white to off-white powder. | |
| Tinosan Diclosan | Hydroxydichlorodiphenyl ether exhibits the capacity to halt the proliferation of cancer cells, thereby displaying promise in therapeutic applications against leukemia and breast cancer. Notably, the compound also showcases clinical relevance in treating skin conditions such as psoriasis and eczema. The multifaceted properties exhibited by Hydroxydichlorodiphenyl ether offer a broad spectrum of potential clinical applications. Category: Anti-tumor apis. Synonyms: SONECLOSAN. 5-chloro-2-(4-chlorophenoxy)phenol. DICLOSAN. Soneclosan [INN]. Hydroxydichlorodiphenyl ether. CAS No. 3380-30-1. Product ID: API3380301. Molecular formula: C12H8Cl2O2. Mole weight: 255.09. EINECS: 429-290-0. SMILES: C1=CC(=CC=C1OC2=C(C=C(C=C2)Cl)O)Cl. | |
| Tioconazole | Tioconazole is a broad-spectrum imidazole antifungal with activity against dermatophytes, yeasts (including Candida species), Gram-positive bacteria, and certain protozoa (Trichomonas vaginalis). Its chemical structure features a thiazole ring rather than the imidazole ring found in most azole antifungals, which contributes to its broader spectrum of activity. The thiazole ring substitution imparts greater lipophilicity and enhanced keratin-binding properties. Applications: Tioconazole is indicated for the topical treatment of tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and cutaneous candidiasis. Category: Active pharmaceutical ingredients. Synonyms: 1-(2-((2-chloro-3-thienyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol;vagistat. CAS No. 65899-73-2. Product ID: API65899732. Molecular formula: C16H13Cl3N2OS. Mole weight: 387.7. EINECS: 265-973-8. InChIKey: QXHHHPZILQDDPS-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Tiopronin | Tiopronin is a novel derivative containing sulfhydryl glycine, which is mainly used to improve liver function of various acute and chronic hepatitis, fatty liver, alcoholic liver, and drug-induced liver injury. Category: Active pharmaceutical ingredients. Synonyms: A-MERCAPTOPROPIONYL GLYCINE;ALPHA-MERCAPTO PROPIONYL GLYCINE;LABOTEST-BB LT00451995;TIOPRONIN;N-(2-MERCAPTOPROPIONYL)GLYCINE. CAS No. 1953-02-2. Product ID: API195322. Molecular formula: C5H9NO3S. Mole weight: 163.19. EINECS: 217-778-4. | |
| Tiotropium Bromide | A scopolamine derivative and CHOLINERGIC ANTAGONIST that functions as a BRONCHODILATOR AGENT. It is used in the treatment of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Category: Active pharmaceutical ingredients. Synonyms: Spiriva;Tiotropium (Bromide);Spiriva Handihaler. Grades: USDMF/CEP. CAS No. 136310-93-5. Product ID: API136310935. Molecular formula: C19H22BrNO4S2. Mole weight: 472.4. EINECS: 680-665-7. Appearance: White or off-white crystalline powder. Standard: Facility GMP. | |
| TipranavirP | Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor.Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Category: Active pharmaceutical ingredients. CAS No. 174484-41-4. Product ID: API174484414. Molecular formula: C31H33F3N2O5S. Mole weight: 602.66. | |
| Tizanidine Hydrochloride | Tizanidine hydrochloride is a centrally acting alpha-2 adrenergic agonist used as a short-acting muscle relaxant for spasticity management. The drug is chemically an imidazole derivative unrelated to other muscle relaxants. Applications: Tizanidine is indicated for the management of spasticity associated with multiple sclerosis, spinal cord injury, cerebral palsy, and stroke. it is also used off-label for chronic tension-type headaches and myofascial pain syndromes. Category: Active pharmaceutical ingredients. Synonyms: Tizanidine Hcl; DS 103-282; AN021; DS-103-282; B53E3NMY5C; Tizanidine (as hydrochloride); ONTRALFY. CAS No. 64461-82-1. Product ID: API0231623. Molecular formula: C9H9Cl2N5S. Mole weight: 290.17. EINECS: 630-412-1. InChIKey: ZWUKMNZJRDGCTQ-UHFFFAOYSA-N. Appearance: White to off-white fine crystalline powder. | |
| Tofacitinib | Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and is currently under investigation for the treatment of psoriasis. Category: Other apis. Synonyms: Tasocitinib. 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. CAS No. 477600-75-2. Product ID: API477600752. Molecular formula: C16H20N6O. Mole weight: 312.37. EINECS: 689-145-4. SMILES: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N. Appearance: Yellow foam. | |
| Tofacitinib Citrate | Used to treat moderately to severely active Rheumatoid Arthritis. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and an antirheumatic drug. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 540737-29-9. Product ID: API540737299. Molecular formula: C22H28N6O8. Mole weight: 504.5. EINECS: 638-826-4. Appearance: White to Off-white Solid. Standard: Facility GMP. | |
| Tolmetin Sodium | Tolmetin Sodium is the sodium salt of tolmetin, a nonsteroidal anti-inflammatory drug (NSAID) of the pyrrole acetic acid class. It is structurally distinguished from most NSAIDs by its aromatic pyrrolyl acetic acid core, with a para-methylbenzoyl substituent at the N-1 position. Applications: Indicated for the treatment of rheumatoid arthritis, osteoarthritis, and juvenile rheumatoid arthritis. tolmetin sodium is a pyrrole acetic acid class nsaid that provides anti-inflammatory, analgesic, and antipyretic effects through cyclooxygenase inhibition, with a structurally unique pyrrolyl ring system. Category: Active pharmaceutical ingredients. Synonyms: sodium 1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetate;1-Methyl-5-(p-toluoyl)-1H-pyrrole-2-acetic acid sodium salt. CAS No. 35711-34-3. Product ID: API35711343. Molecular formula: C15H14NNaO3. Mole weight: 279.27. EINECS: 252-687-3. InChIKey: QGUALMNFRILWRA-UHFFFAOYSA-M. | |
| Tolrestat | Tolrestat (AY-27773) is a potent inhibitor of aldose reductase (IC50 = 35 nM). Category: Active pharmaceutical ingredients. Synonyms: AY-27773. CAS No. 82964-04-3. Product ID: API82964043. Molecular formula: C16H14F3NO3S. Mole weight: 357.35. | |
| Tolterodine Fumarate | One of the impurities of Tolterodine, which is a muscarinic receptor antagonist and has been found to be effective against urinary incontinence. Category: Other apis. Synonyms: UNII-HH7RXJ4PW1. HH7RXJ4PW1. Phenol, 2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-methyl-, (2E)-2-butenedioate (1:1) (salt). CAS No. 615254-93-8. Product ID: API615254938. Molecular formula: C26H35NO5. Mole weight: 441.6. SMILES: CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.C(=CC(=O)O)C(=O)O. Appearance: Solid. | |
| Tolterodine Tartrate | Tolterodine Tartrate is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. Category: Active pharmaceutical ingredients. CAS No. 124937-52-6. Product ID: API124937526. Molecular formula: C26H37NO7. Mole weight: 475.574. | |
| Torsemide | Torsemide is a high-ceiling loop diuretic with a longer duration of action and greater oral bioavailability compared to furosemide. The drug is a pyridine-sulfonylurea derivative that acts on the thick ascending limb of the loop of Henle. Applications: Torsemide is indicated for the treatment of edema associated with congestive heart failure, hepatic cirrhosis, and renal disease, as well as for hypertension. its superior bioavailability makes it more reliable in patients with edema-related gut wall edema. some studies suggest lower mortality and hospitalization rates when torsemide is used in heart failure compared to furosemide, though it is not yet universally preferred. Category: Active pharmaceutical ingredients. Synonyms: Luprac; Torasemida; Torasemidum; BM-02015; AC-4464; Torasemide anhydrous. CAS No. 56211-40-6. Product ID: API0231591. Molecular formula: C16H20N4O3S. Mole weight: 348.4. EINECS: 637-197-3. InChIKey: NGBFQHCMQULJNZ-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| Tosufloxacin hydrochloride | Tosufloxacin hydrochloride is a fluoroquinolone antibacterial agent used to treat bacterial infections. Category: Active pharmaceutical ingredients. Synonyms: A-61827 hydrochloride, T-3262 hydrochloride. CAS No. 104051-69-6. Product ID: API104051696. Molecular formula: C19H16ClF3N4O3. Mole weight: 440.8. | |
| Tosufloxacin tosilate | Tosufloxacin tosilate is a fluoroquinolone antibiotic. Category: Active pharmaceutical ingredients. CAS No. 107097-79-0. Product ID: API107097790. Molecular formula: C26H23F3N4O6S. Mole weight: 594.57. | |
| Tosufloxacintosufloxacin tosilate | Tosufloxacin (Ozex) is a quinolone antimicrobial agent and potent inhibitor of the metabolism of theophylline. Category: Active pharmaceutical ingredients. CAS No. 108138-46-1. Product ID: API108138461. Molecular formula: C19H15F3N4O3. Mole weight: 404.34. | |
| Tosufloxacin tosylate | Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections. Category: Active pharmaceutical ingredients. CAS No. 115964-29-9. Product ID: API115964299. Molecular formula: C26H23F3N4O6S. Mole weight: 576.54. | |
| Tosufloxacin tosylate hydrate | Tosufloxacin tosylate hydrate (A-61827 tosylate hydrate) is a fluoroquinolone antibacterial agent that is used to treat susceptible infections. Category: Active pharmaceutical ingredients. Synonyms: Tosufloxacin p-Toluenesulfonate Hydrate, A-61827 tosylate hydrate, T-3262 Tosylate Hydrate. CAS No. 1400591-39-0. Product ID: API1400591390. Molecular formula: C26H25F3N4O7S. Mole weight: 594.6. | |
| Tovorafenib | Tovorafenib is an orally active and selective inhibitor of pan-Raf kinase. Tovorafenib can be used for the study of glioma. Category: Active pharmaceutical ingredients. Synonyms: TAK-580; MLN 2480. CAS No. 1096708-71-2. Product ID: API1096708712. Molecular formula: C17H12Cl2F3N7O2S. Mole weight: 506.29. | |
| TPX-0046 | TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib. Category: Active pharmaceutical ingredients. CAS No. 2359650-19-2. Product ID: API2359650192. Molecular formula: C21H21FN6O3. Mole weight: 424.43. | |
| Trabectedin | Trabectedin (Ecteinascidin-743 or ET-743) is a novel antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo. Category: Active pharmaceutical ingredients. CAS No. 114899-77-3. Product ID: API114899773. Molecular formula: C39H43N3O11S. Mole weight: 761.837. | |
| Tramadol Hydrochloride | Tramadol hydrochloride is a centrally acting synthetic analgesic with a dual mechanism of action, positioned between weak opioids and nonsteroidal anti-inflammatory drugs. Applications: Tramadol is indicated for moderate to moderately severe pain, including postoperative, musculoskeletal, and neuropathic pain. it is also used for osteoarthritis and chronic low back pain when nonopioid analgesics are insufficient. the extended - release formulation is reserved for around - the - clock pain management. Category: Active pharmaceutical ingredients. Synonyms: Tradonal; Tramadol HCl; Amadol; Mabron; Zydol; ConZip; Synapryn. CAS No. 36282-47-0. Product ID: API0231629. Molecular formula: C16H26ClNO2. Mole weight: 299.83. EINECS: 258-662-3. InChIKey: PPKXEPBICJTCRU-XMZRARIVSA-N. Appearance: White crystalline odorless powder. | |
| Trametinib | Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis. Category: Active pharmaceutical ingredients. CAS No. 871700-17-3. Product ID: API871700173. Molecular formula: C26H23FIN5O4. Mole weight: 615.39. | |
| Trametinib (DMSO solvate) | Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and selective MEK inhibitor that specifically inhibits MEK1/2 (IC50: 2 nM). Category: Active pharmaceutical ingredients. CAS No. 1187431-43-1. Product ID: API1187431431. Molecular formula: C28H29FIN5O5S. Mole weight: 693.53. | |
| trans-Pralsetinib | trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET). Category: Active pharmaceutical ingredients. CAS No. 2097132-93-7. Product ID: API2097132937. Molecular formula: C27H32FN9O2. Mole weight: 533.6. | |
| Trastuzumab deruxtecan | Trastuzumab deruxtecan (T-DXd) is an antibody-active molecule conjugate (ADC) with anticancer and antitumor activity, which is composed of a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2) coupled to a topoisomerase I inhibitor (DXd). Trastuzumab deruxtecan has an improved effect on the treatment of HER2-positive breast cancer and gastric cancer. Category: Active pharmaceutical ingredients. CAS No. 1826843-81-5. Product ID: API1826843815. Mole weight: 145 kDa (average). | |
| Trazodone hydrochloride | Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. Category: Active pharmaceutical ingredients. CAS No. 25332-39-2. Product ID: API25332392. Molecular formula: C19H23Cl2N5O. Mole weight: 408.325. Appearance: off-white powder. Standard: USP/EP. | |
| Trehalose | Trehalose is a humectant and moisturizer, it helps bind water in the skin and increase the skins moisture content. It is a naturally occurring plant sugar. Applications: Cosmetics. Category: Natural extract. Synonyms: D-(+)-TREHALOSE;D-TREHALOSE;(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-oxybis(2-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol);TREHALOSE(P);ALPHA-D-TREHALOSE;ALPHA,ALPHA-D-TREHALOSE;MYCOSE. CAS No. 99-20-7. Product ID: PIPE-0267. Molecular formula: C12H22O11. Mole weight: 342.3. EINECS: 202-739-6. Appearance: Powder. Standard: In house. | |
| Trelagliptin | Trelagliptin (SYR-472) is a highly specific, long-acting DPP-4 inhibitor. Category: Active pharmaceutical ingredients. CAS No. 865759-25-7. Product ID: API865759257. Molecular formula: C18H20FN5O2. Mole weight: 357.38. | |
| Trenbolone enanthate | Trenbolone enanthate. Category: Apis for androgens. CAS No. 472-61-546. Product ID: API47261546. | |
| Treprostinil Sodium | Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Category: Active pharmaceutical ingredients. Synonyms: Remodulin. Treprostinil (sodium). 7JZ75N2NT6. CAS No. 289480-64-4. Product ID: API289480644. Molecular formula: C23H33NaO5. Mole weight: 412.5. EINECS: 695-793-9. SMILES: CCCCCC(CCC1C(CC2C1CC3=C(C2)C(=CC=C3)OCC(=O)[O-])O)O.[Na+]. | |
| Triacetin | It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. It has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug. It is functionally related to an acetic acid. Category: Other chemicals. Synonyms: Glyceryl triacetate. Glycerol triacetate. Enzactin. CAS No. 102-76-1. Product ID: CHE102761. Molecular formula: C3H5(OCOCH3)3. Mole weight: 218.2. EINECS: 203-051-9. SMILES: CC(=O)OCC(COC(=O)C)OC(=O)C. Appearance: colourless oily liquid with a very slight, ethereal, fruity odour. | |
| Triamcinolone acetonide-d6 | Triamcinolone acetonide-d6 is a deuterated compound of Triamcinolone acetonide. Triamcinolone acetonide has a CAS number of 76-25-5. Triamcinolone acetonide is a Corticosteroid. Category: Active pharmaceutical ingredients. CAS No. 352431-33-5. Product ID: API352431335. Molecular formula: C24H25D6FO6. Mole weight: 440.53. | |
| Triamcinolone Diacetate | Triamcinolone Diacetate is a synthetic glucocorticoid corticosteroid administered primarily via intra-articular, intralesional, or intramuscular routes as an injectable suspension. The diacetate ester provides a microcrystalline suspension formulation that allows for extended depot-like release from injection sites, prolonging the duration of anti-inflammatory action compared to aqueous solutions of the base steroid. Applications: Triamcinolone diacetate is indicated for intra-articular, intrabursal, tendon sheath, and intralesional administration in the treatment of rheumatoid arthritis, osteoarthritis, acute gouty arthritis, and various inflammatory conditions of joints and soft tissues. it is also used for the treatment of allergic and inflammatory conditions of the skin, respiratory tract, and eyes, and for certain adrenal insufficiency states. Category: Active pharmaceutical ingredients. Synonyms: 16-(Acetyloxy)-9-fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate. CAS No. 67-78-7. Product ID: API67787. Molecular formula: C25H31FO8. Mole weight: 478.5. EINECS: 200-669-0. InChIKey: XGMPVBXKDAHORN-RBWIMXSLSA-N. Appearance: White powder. | |
| Tribulus Terrestris Extract | Tribulus Terrestris Extract is an extract standardized to contain steroidal saponins and polyphenol antioxidants. It is used in dietary supplements at the highest levels as a natural herb extract for maintaining cardiovascular and metabolic health and vitality. Tribulus Terrestris Extract can be used in professional supplement formulas to promote heart and metabolic health and healthy aging. Applications: Tribulus terrestris extract is used in nutraceuticals for blood pressure support, lipid balance and to provide the heart with anti-ischemic effects. it is also used in natural supplements to promote reproductive health, hormonal health and kidney stone prevention, glucose control and to combat inflammation and infections when applied topically or taken internally. Category: Natural extract. Product ID: PIPE-0445. | |
| Trichlormethiazide | Trichlormethiazide is a thiazide diuretic belonging to the benzothiadiazine class, characterized by its high potency and prolonged duration of action compared to other agents in this family. It is available in oral tablet form and acts on the distal convoluted tubule of the nephron. This agent is structurally related to hydrochlorothiazide but exhibits approximately ten times the potency on a milligram basis. Applications: It is indicated for the management of hypertension, either as monotherapy or in combination with other antihypertensive agents, as well as for the treatment of edema associated with congestive heart failure, hepatic cirrhosis, and renal dysfunction. its high potency allows for lower milligram dosing compared to standard thiazides, with once-daily administration providing sustained diuretic and antihypertensive effects. as with all thiazides, electrolyte monitoring is essential during chronic use. Category: Antihypertensive apis. Synonyms: Metahydrin; Trichlormetazid; Trichlormethiazid; Diurazida; Trichlorex; 3-Dichloromethylhydrochlorothiazide; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide; NSC-61560; DTXSID7023699. CAS No. 133-67-5. Product ID: API0231526. Molecular formula: C8H8Cl3N3O4S2. Mole weight: 380.7. EINECS: 205-118-8. InChIKey: LMJSLTNSBFUCMU-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Triclabendazole | Triclabendazole is a benzimidazole anthelmintic agent specifically indicated for the treatment of fascioliasis, or liver fluke infection caused by Fasciola hepatica and Fasciola gigantica. It is available in oral tablet formulation and is distinguished from other benzimidazoles by its selective activity against both immature and adult flukes. The drug is the only agent recommended for fascioliasis by the World Health Organization. Applications: It is indicated for the treatment of fascioliasis in both adults and children, typically administered as one or two oral doses based on body weight. it is also used off-label for the treatment of paragonimiasis and intestinal trematode infections. due to its poor activity against nematodes and cestodes, it is not a general-purpose anthelmintic. common adverse effects include abdominal pain, nausea, and transient elevation of liver enzymes. Category: Antiparasitic apis. Synonyms: Fasinex; Triclabendazol; Egaten; Triclabendazolum; 5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole; NVP-EGA230; EGA230B. CAS No. 68786-66-3. Product ID: API0231550. Molecular formula: C14H9Cl3N2OS. Mole weight: 359.7. EINECS: 614-728-7. InChIKey: NQPDXQQQCQDHHW-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Triclosan TCS DP-300 | An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. Category: Active pharmaceutical ingredients. Synonyms: triclosan. 5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL. Cloxifenolum. Irgasan. CAS No. 3380-34-5. Product ID: API3380345. Molecular formula: C12H7Cl3O2. Mole weight: 289.5. EINECS: 222-182-2. SMILES: C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl. Appearance: White to off-white crystalline powder. | |
| Trifluoperazine | Trifluoperazine is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 117-89-5. Product ID: API117895. Molecular formula: C21H24F3N3S. Mole weight: 407.5. | |
| Trifluoperazine dihydrochloride | Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. Category: Active pharmaceutical ingredients. CAS No. 440-17-5. Product ID: API440175. Molecular formula: C21H26Cl2F3N3S. Mole weight: 480.43. | |
| Trifluoperazine N-Glucuronide | Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity. Category: Active pharmaceutical ingredients. CAS No. 165602-90-4. Product ID: API165602904. Molecular formula: C27H32F3N3O6S. Mole weight: 583.62. | |
| Trifluperidol HCl | Trifluperidol, a dopamine D2-receptor antagonist, is used to treat schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 2062-77-3. Product ID: API2062773. Molecular formula: C22H24ClF4NO2. Mole weight: 445.88. | |
| Triflupromazine | Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic. Category: Active pharmaceutical ingredients. CAS No. 146-54-3. Product ID: API146543. Molecular formula: C18H19F3N2S. Mole weight: 352.42. | |
| Triflupromazine hydrochloride | Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists. Category: Active pharmaceutical ingredients. Synonyms: Neoprin, Fluopromazine hydrochloride, Fluorofen, Flumazin. CAS No. 1098-60-8. Product ID: API1098608. Molecular formula: C18H20ClF3N2S. Mole weight: 388.88. | |
| Trifluridine | Trifluridine is a fluorinated pyrimidine nucleoside analogue with potent antiviral activity, formulated exclusively as a topical ophthalmic solution. It is structurally related to thymidine and acts as a DNA synthesis inhibitor. The drug is approved for the treatment of keratitis caused by herpes simplex virus and is considered the most efficacious topical agent for this indication. Applications: Trifluridine ophthalmic solution is indicated for the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis caused by herpes simplex virus types 1 and 2. it is typically applied five times daily until corneal re-epithelialization occurs. compared to idoxuridine and vidarabine, trifluridine demonstrates superior efficacy and lower toxicity. Category: Active pharmaceutical ingredients. Synonyms: Viroptic; Trifluoromethyldeoxyuridine; Trifluridina; F3TDR; Trifluridinum; 5-(Trifluoromethyl)deoxyuridine; TFDU; 5-Trifluoromethyl-2-deoxyuridine. CAS No. 70-00-8. Product ID: API0231581. Molecular formula: C10H11F3N2O5. Mole weight: 296.2. EINECS: 200-722-8. InChIKey: VSQQQLOSPVPRAZ-RRKCRQDMSA-N. Appearance: White crystalline powder. | |
| Trifluridine/tipiracil hydrochloride mixture | Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and tipiracil hydrochloride (TTP) in a 2:1 molar ratio. Category: Active pharmaceutical ingredients. Synonyms: Trifluridine-tipiracil hydrochloride mixture, TAS-102, TAS102, TAS 102. CAS No. 733030-01-8. Product ID: API733030018. Molecular formula: C29H34Cl2F6N8O12. Mole weight: 871.53. | |
| Trilostane | Trilostane is a synthetic steroid-derived inhibitor of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD), the enzyme that catalyzes the conversion of dehydroepiandrosterone (DHEA) to androstenedione and progesterone to testosterone in the adrenal and gonadal steroidogenesis pathways. As a competitive inhibitor of 3 beta-HSD, it reduces the synthesis of androgen and estrogen steroid hormones. Applications: Trilostane is indicated for the treatment of cushing's syndrome in veterinary medicine, where it reduces excessive cortisol production. it has also been investigated in human medicine for the treatment of cushing's syndrome, breast cancer, and conditions of androgen excess. Category: Intermediates. Synonyms: (4a,5a,17b)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile;5a-Androstane-2a-carbonitrile, 4a,5-epoxy-17b-hydroxy-3-oxo-;Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4a,5a,17b)-. CAS No. 13647-35-3. Product ID: INT13647353. Molecular formula: C20H27NO3. Mole weight: 329.43. EINECS: 237-133-0. InChIKey: KVJXBPDAXMEYOA-CXANFOAXSA-N. Appearance: White to off-white powder. | |
| Trioctyl phosphate | Tris(2-ethylhexyl) phosphate (CAS# 78-42-2) is a useful research chemical. Category: Active pharmaceutical ingredients. Synonyms: Tris(2-ethylhexyl) phosphate. Tris(2-ethylhexyl)phosphate. Disflamoll TOF. Kronitex TOF. CAS No. 78-42-2. Product ID: API78422. Molecular formula: C24H51O4P. Mole weight: 434.6. EINECS: 201-116-6. SMILES: CCCCC(CC)COP(=O)(OCC(CC)CCCC)OCC(CC)CCCC. Appearance: clear colorless to pale yellow liquid. | |
| Tripelennamine Hydrochloride | Tripelennamine Hydrochloride is a first-generation antihistamine (H1 receptor antagonist) of the ethylenediamine class, notable for its relatively rapid onset and moderate duration of action. The hydrochloride salt provides enhanced aqueous solubility and is suitable for both oral and topical (dermal) administration. It has been used clinically since the mid-20th century for allergy management. Applications: Tripelennamine hydrochloride is indicated for the symptomatic treatment of allergic conditions including allergic rhinitis, hay fever, urticaria, and allergic skin reactions. Category: Active pharmaceutical ingredients. Synonyms: 2-(benzyl(2-(dimethylamino)ethyl)amino)-pyridinmonohydrochloride. CAS No. 154-69-8. Product ID: API154698. Molecular formula: C16H22ClN3. Mole weight: 291.82. EINECS: 205-833-5. InChIKey: FSSICIQKZGUEAE-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Triprolidine Hydrochloride | Triprolidine Hydrochloride is a potent first-generation antihistamine of the propylamine (alkylamine) class, recognized for its relatively high H1 receptor binding affinity and favorable pharmacokinetic profile with a rapid onset and moderate duration of action. The hydrochloride salt is well absorbed orally and provides consistent plasma concentrations at therapeutic doses. It is frequently combined with sympathomimetic decongestants in multi-symptom cold and allergy preparations. Applications: Triprolidine hydrochloride is indicated for the symptomatic relief of allergic rhinitis, common cold symptoms, and allergic skin conditions characterized by itching and urticaria. Category: Active pharmaceutical ingredients. Synonyms: trans-Triprolidine hydrochloride;2-[(1E)-1-(4-Methylphenyl)-3-pyrrolizino-1-propenyl]pyridine·hydrochloride. CAS No. 550-70-9. Product ID: API550709. Molecular formula: C19H23ClN2. Mole weight: 314.9. EINECS: 208-985-0. InChIKey: WYUYEJNGHIOFOC-NWBUNABESA-N. Appearance: Powder. | |
| Trisodium phosphate | TSPs are used as cleaning agent, lubricant, food additive, stain remover and degreaser.The item of commerce is often partially hydrated and may range from anhydrous Na3PO4, to the dodecahydrate, Na3PO4·12 H2O. Category: Mineral salts and nutrients. Synonyms: Sodium phosphate. Sodium phosphate tribasic. Tribasic sodium phosphate. CAS No. 7601-54-9. Product ID: CHE7601549. Molecular formula: Na3PO4. Mole weight: 163.941. EINECS: 265-604-0. SMILES: [O-]P(=O)([O-])[O-].[Na+].[Na+].[Na+]. Appearance: Colorless to white solid. | |
| Tromethamine | Tromethamine (also known as THAM or tris(hydroxymethyl)aminomethane) is a weak organic base with a pKa of 7.8 at 25 degrees C, making it an effective buffer in the physiological pH range. As a pharmaceutical excipient and active agent, it neutralizes both strong acids and acidic metabolites, and is particularly useful in situations where sodium bicarbonate buffering is contraindicated. Applications: Tromethamine is indicated for use as a systemic alkalinizing agent in the correction of metabolic acidosis, particularly in settings where sodium bicarbonate is suboptimal, such as in patients with fluid restriction, hypernatremia, or impaired cardiac function. it is also used as a buffering agent in pharmaceutical formulations and cosmetics. Category: Active pharmaceutical ingredients. Synonyms: Tris(hydroxymethyl)aminomethane. CAS No. 77-86-1. Product ID: API77861. Molecular formula: C4H11NO3. Mole weight: 121.14. EINECS: 201-064-4. InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N. Appearance: White powder. | |
| Tropicamide | Tropicamide is a synthetic anticholinergic agent of the tropane class, derived from tropic acid and a substituted pyridine base. It is specifically used in ophthalmology and characterized by the shortest duration of action among clinically employed mydriatic and cycloplegic agents. Applications: Used in ophthalmology for diagnostic mydriasis and cycloplegia. tropicamide is a short-acting anticholinergic agent with the fastest onset and shortest duration of action among clinically employed mydriatics, providing convenient pupil dilation for fundus examination and refraction assessment with minimal post-procedural recovery time. Category: Active pharmaceutical ingredients. Synonyms: (2R)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylMethyl)propanaMide. CAS No. 1508-75-4. Product ID: API1508754. Molecular formula: C17H20N2O2. Mole weight: 284.35. EINECS: 216-140-2. InChIKey: BGDKAVGWHJFAGW-UHFFFAOYSA-N. Appearance: White solid. | |
| Troriluzole | Troriluzole is an orally active glutamate modulator with anticancer activity.Troriluzole enhances the expression of excitatory amino acid transporters located in glial cells and is used in the study of spinocerebellar ataxia, Alzheimer's disease, and generalized anxiety disorder (GAD). Category: Active pharmaceutical ingredients. CAS No. 1926203-09-9. Product ID: API1926203099. Molecular formula: C15H16F3N5O4S. Mole weight: 419.38. | |
| Tucidinostat | Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9. Category: Active pharmaceutical ingredients. CAS No. 1616493-44-7. Product ID: API1616493447. Molecular formula: C22H19FN4O2. Mole weight: 390.41. | |
| Ubenimex | Bestatin is a natural, broad-spectrum, and competitive aminopeptidase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 58970-76-6. Product ID: API58970766. Molecular formula: C16H24N2O4. Mole weight: 308.4. Appearance: Crystalline or powder. | |
| Ufenamate | Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for the treatment of skin diseases. Category: Active pharmaceutical ingredients. CAS No. 67330-25-0. Product ID: API67330250. Molecular formula: C18H18F3NO2. Mole weight: 337.34. | |
| Umbralisib | Umbralisib (TGR 1202) is a PI3Kδ inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1532533-67-7. Product ID: API1532533677. Molecular formula: C31H24F3N5O3. Mole weight: 571.55. | |
| Umbralisib hydrochloride | Umbralisib hydrochloride is a novel PI3Kδ inhibitor (IC50 and EC50 of 22.2 nM and 24.3 nM, respectively). Umbralisib hydrochloride is also active against CK1ε (EC50: 6.0 μM). Category: Active pharmaceutical ingredients. Synonyms: RP5264 hydrochloride, TGR-1202 hydrochloride. CAS No. 1532533-78-0. Product ID: API1532533780. Molecular formula: C31H25ClF3N5O3. Mole weight: 608.01. | |
| Umbralisib R-enantiomer | Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ). Category: Active pharmaceutical ingredients. CAS No. 1532533-69-9. Product ID: API1532533699. Molecular formula: C31H24F3N5O3. Mole weight: 571.55. | |
| Umbralisib sulfate | Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies. Category: Active pharmaceutical ingredients. Synonyms: TGR-1202 sulfate; RP-5264 sulfate,TGR-1202 sulfate,RP-5264 sulfate. CAS No. 1532533-75-7. Product ID: API1532533757. Molecular formula: C31H26F3N5O7S. Mole weight: 669.63. | |
| Umbralisib tosylate | Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies. Category: Active pharmaceutical ingredients. Synonyms: RP5264 tosylate,TGR-1202 tosylate ; RP5264 tosylate,TGR-1202 tosylate. CAS No. 1532533-72-4. Product ID: API1532533724. Molecular formula: C38H32F3N5O6S. Mole weight: 743.75. | |
| Upadacitinib | Upadacitinib is a potent and selective JAK inhibitor. Upadacitinib is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Upadacitinib demonstrates efficacy in rat arthritis models. Category: Active pharmaceutical ingredients. CAS No. 1607431-21-9. Product ID: API1607431219. Molecular formula: C21H33F3N6O11. Mole weight: 602.521. | |
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