Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| PCMX | 4-chloro-3,5-dimethylphenol is a member of the class of phenols that is 3,5-xylenol which is substituted at position 4 by chlorine. It is bactericidal against most Gram-positive bacteria but less effective against Staphylococci and Gram-negative bacteria, and often inactive against Pseudomonas species. It is ineffective against bacterial spores. It has a role as an antiseptic drug, a disinfectant and a molluscicide. It is a member of phenols and a member of monochlorobenzenes. It is functionally related to a 3,5-xylenol. Category: Active pharmaceutical ingredients. Synonyms: 4-Chloro-3,5-dimethylphenol. chloroxylenol. Dettol. CAS No. 88-04-0. Product ID: API88040. Molecular formula: C8H9ClO. Mole weight: 156.61. EINECS: 201-793-8. SMILES: CC1=CC(=CC(=C1Cl)C)O. Appearance: White to Off-white Solid. |  |
| PD 117588 | PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st. Category: Active pharmaceutical ingredients. CAS No. 99734-97-1. Product ID: API99734971. Molecular formula: C20H23F2N3O3. Mole weight: 391.41. | |
| Pectin | Pectin is a naturally occurring polysaccharide present in the cell walls of plants. It is mainly extracted from citrus peel and apple pomace. Pectin is comprised mainly of D-galacturonic acid polymerized units joined through alpha-1,4 linkages. Its primary functional property is its degree of esterification (DE), and depending on DE, pectin is either categorized as a High Methoxyl or Low Methoxyl pectin. The DE directly affects the way that pectin gels. Applications: Pectin is commonly used in the food industry as gelling agent for jams, jellies, and fruit preserves. it also acts as a stabilizer in dairy-based foods (yogurts, desserts) and beverages based on fruit pulp. pectin is used in products with reduced sugar content or sugar-free varieties to create texture in food. pectin is also commonly used as a pharmaceutical binder in tablet coatings, in encapsulation of targeted drug delivery systems as well as in wound healing dressings. pectin is commonly used to increase viscosity of cosmetic creams. it is also used as a film-forming agent in edible packaging. in nutraceuticals, it is used as a soluble dietary fiber. Category: Binder excipients. CAS No. 9000-69-5. Product ID: PIE-0349. Molecular formula: (C6H10O7)n. EINECS: 232-553-0. Appearance: Powder. | |
| Pefloxacin Mesylate | Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. Category: Active pharmaceutical ingredients. CAS No. 70458-95-6. Product ID: API70458956. Molecular formula: C18H24FN3O6S. Mole weight: 429.46. | |
| Pefloxacin Mesylate Dihydrate | Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase). Category: Active pharmaceutical ingredients. CAS No. 149676-40-4. Product ID: API149676404. Molecular formula: C17H20FN3O3·CH4O3S·2H2O. Mole weight: 465.49. | |
| Pegaptanib sodium | Pegaptanib sodium, an RNA aptamer specifically targeting vascular endothelial growth factor (VEGF)-165, holds great promise for investigating neovascular age-related macular degeneration (AMD). Category: Active pharmaceutical ingredients. CAS No. 222716-86-1. Product ID: API222716861. | |
| Pegcetacoplan | Pegcetacoplan is a PEGylated, synthetic, cyclic peptide developed as a targeted inhibitor of complement C3. Pegcetacoplan has a prolonged duration of action that is able to provide sustained inhibition of immune-mediated disorders. Applications: Pegcetacoplan is indicated to treat adults with pnh and to treat geographic atrophy in patients with age-related macular degeneration. it is also indicated to treat c3 glomerulopathy and primary immune complex membranoproliferative glomerulonephritis in adults and children to reduce proteinuria. Category: Peptide apis. Synonyms: Pegcetacoplan acetate; APL-2. CAS No. 2019171-69-6. Product ID: API2019171696. Molecular formula: C62H100N16O23S2. Mole weight: 1501.7. InChIKey: HWGGLQKUJCPSAC-OANAUQNASA-N. | |
| PEI Transfection Reagent | PEI Transfection Reagent is an optimized, linear polyethylenimine based formulation. This chemically synthesized product contains no animal-derived ingredients, is suitable for both small-scale and large-scale applications and. Because it is cost-effective, highly scalable and has high transfection efficiency and low cytotoxicity, it has become the industry standard for transient gene expression in high-performance cell lines. Applications: Pei transfection reagent is used for scalable gene delivery applications, including efficient co-transfection of multiple plasmids. main applications are for the production of recombinant virus vectors and for the rapid, transient expression of recombinant proteins and antibodies in established cell lines. Category: Biochemical reagents. Synonyms: Polyethyleneimine. Grades: DMF. Product ID: PIPB-0802. Appearance: Colorless liquid. Standard: Facility GMP. | |
| Pemigatinib | Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR, with IC50 values of 0.4 nM for FGFR1, 0.5 nM for FGFR2, 1.2 nM for FGFR3, and 30 nM for FGFR4. Category: Active pharmaceutical ingredients. CAS No. 1513857-77-6. Product ID: API1513857776. Molecular formula: C24H27F2N5O4. Mole weight: 487.5. | |
| Pemoline | Pemoline is a central nervous system stimulant that was previously approved for the treatment of attention-deficit/hyperactivity disorder (ADHD). It is a non-amphetamine, oxazolidinone derivative with a longer duration of action than methylphenidate. Applications: Historically, pemoline was indicated for adhd in children and adolescents as a second-line agent when other stimulants were ineffective or poorly tolerated. Category: Active pharmaceutical ingredients. Synonyms: Phenoxazole; Azoksodon; Phenylisohydantoin; Tradon; Azoxodon. CAS No. 2152-34-3. Product ID: API0231608. Molecular formula: C9H8N2O2. Mole weight: 176.17. EINECS: 218-438-8. InChIKey: NRNCYVBFPDDJNE-UHFFFAOYSA-N. Appearance: White crystalline powder. | |
| Penfluridol | Penfluridol (TLP-607) is a highly potent antipsychotic. Category: Active pharmaceutical ingredients. CAS No. 26864-56-2. Product ID: API26864562. Molecular formula: C28H27ClF5NO. Mole weight: 523.97. | |
| Penicillin G Benzathine | Penicillin G benzathine is the benzathine salt form of natural penicillin G, formulated as a sterile aqueous suspension for deep intramuscular injection only. Due to its extremely low solubility and slow absorption, it is classified as a prescription antibiotic against intravenous administration. Applications: Penicillin g benzathine is indicated for treatment of group a streptococcal upper respiratory infections and for syphilis of all stages including primary, secondary, and latent disease. it serves as the gold standard for rheumatic fever prophylaxis with monthly intramuscular injections and is also used for yaws, bejel, and pinta. Category: Antibacterial apis. Synonyms: Benzathine Penicillin; Benzathine Benzylpenicillin. CAS No. 41372-02-5. Product ID: API0232893. Molecular formula: C48H64N6O12S2. Mole weight: 981.2. EINECS: 804-898-2. InChIKey: WIDKTXGNSOORHA-CJHXQPGBSA-N. Appearance: White crystalline powder. | |
| Penicillin G Potassium | Penicillin G potassium is the potassium salt of natural penicillin G (benzylpenicillin), formulated as a white crystalline powder for parenteral administration. It is supplied as a sterile powder for reconstitution and is intended for intramuscular or intravenous use due to its poor oral absorption and acid lability. Each million units contains approximately 1.7 mEq of potassium, requiring consideration in patients with electrolyte imbalances or renal impairment. Applications: Penicillin g potassium is indicated for serious infections caused by susceptible organisms including streptococci, pneumococci, meningococci, and treponema pallidum. specific indications include streptococcal endocarditis, pneumococcal pneumonia, meningococcal meningitis, anthrax, diphtheria, tetanus, gas gangrene, and neurosyphilis. dosing ranges from 2 to 30 million units daily divided every 4 to 6 hours depending on infection severity, with dosage adjustment required in renal impairment. Category: Antibacterial apis. Synonyms: Pfizerpen, Benzylpenicillin potassium, Potassium benzylpenicillin, Penicillin G potassium salt. CAS No. 113-98-4. Product ID: API0232172. Molecular formula: C16H17KN2O4S. Mole weight: 372.48. EINECS: 204-038-0. InChIKey: IYNDLOXRXUOGIU-LQDWTQKMSA-M. Appearance: Colorless or white crystal, or white crystalline powder. | |
| Penicillin G Sodium | Penicillin G sodium is a natural, parenteral beta-lactam antibiotic derived from Penicillium chrysogenum and represents the original member of the penicillin family. It is available as a crystalline powder for reconstitution and intravenous or intramuscular administration. The drug is acid-labile and therefore ineffective orally, necessitating injectable delivery for systemic effect. Applications: This antibiotic remains the drug of choice for infections caused by non-resistant streptococci, treponema pallidum (syphilis), clostridium perfringens, and neisseria meningitidis. it is also used for pneumococcal pneumonia and endocarditis due to penicillin-susceptible strains. high doses are required for central nervous system infections due to limited penetration, and resistance mediated by beta-lactamase is increasingly encountered. Category: Active pharmaceutical ingredients. Synonyms: Crystapen; Benzylpenicillin sodium; BENZYLPENICILLIN SODIUM SALT; American penicillin; Sodium penicillin G. CAS No. 69-57-8. Product ID: API0231579. Molecular formula: C16H17N2NaO4S. Mole weight: 356.4. EINECS: 200-710-2. InChIKey: FCPVYOBCFFNJFS-LQDWTQKMSA-M. Appearance: White to slightly yellow crystalline powder. | |
| Pentetate Zinc Trisodium | Pentetate Zinc Trisodium (Zn-DTPA) is the zinc salt of diethylenetriaminepentaacetic acid (DTPA), a chelating agent structurally related to EDTA but with enhanced capacity for binding actinides and transuranic elements. As the zinc salt, it is used primarily as an alternative to the calcium salt (Ca-DTPA) in the decorporation of internally deposited radioactive and heavy metal contaminants. Applications: Pentetate zinc trisodium is indicated for the treatment of internal contamination with plutonium, americium, and curium in cases of radiation exposure or nuclear accidents. Category: Active pharmaceutical ingredients. Synonyms: Zinc trisodium pentetate. CAS No. 125833-02-5. Product ID: API125833025. Molecular formula: C14H18N3Na3O10Zn. Mole weight: 522.7. InChIKey: HVASDHJNLYRZEA-UHFFFAOYSA-I. | |
| Pentoxyfylline | Pentoxifylline is a non-selective PDE (phosphodiesterase) inhibitor. Inhibits endotoxin-induced synthesis of tumor necrosis factor-a (TNF α). PTX inhibits the adhesion of T cells to the b1 and b2 Integrin ligands VCAM-1 and ICAM-1. Also prevents the down-regulation of microsomal cytochrome P450 caused by lipopolysaccharides.This compound is also a PDE (phosphodiesterase) inhibitor that blocks production of TNF α and other cytokines. Displays antinociceptive activity. Category: Active pharmaceutical ingredients. CAS No. 6493-5-6. Product ID: API6493056. Molecular formula: C13H18N4O3. Mole weight: 278.307. | |
| Pepsin | Pepsin is an enzyme that is secreted in the digestive track of mammals. It works to break down proteins into smaller peptides which can readily be absorbed by the small intestine. Category: Natural extract. Synonyms: IMMOBILIZED PEPSIN;BOVINEPEPSINB;AVIANPEPSIN;BOVINEPEPSINA. CAS No. 9001-75-6. Product ID: PIPE-0361. EINECS: 232-629-3. Appearance: Powder. Standard: In house;USP. | |
| Peramivir | A trihydrate of the anti-infection agent, which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor, used for the treatment of acute uncomplicated influenza. Category: Active pharmaceutical ingredients. Grades: KDMF/DMF/WC. CAS No. 1041434-82-5. Product ID: API1041434825. Molecular formula: C15H34N4O7. Mole weight: 382.453. Standard: In-house/CP Facility GMP. | |
| Perflexane | Perflexane (perfluorohexane, C6F14) is a fully fluorinated alkane belonging to the class of perfluorocarbon (PFC) compounds. All hydrogen atoms are replaced by fluorine, giving it exceptional chemical inertness, very high gas-dissolving capacity, and extreme hydrophobicity. It is the active component in certain ultrasound contrast agent formulations. Applications: Used as the active gas core in ultrasound contrast agent formulations for echocardiography and vascular imaging. perflexane is a perfluorocarbon compound with exceptional acoustic reflectivity and gas stability, providing enhanced ultrasound signal for improved cardiac chamber and blood flow visualization. Category: Active pharmaceutical ingredients. Synonyms: Perfluorohexane. CAS No. 355-42-0. Product ID: API355420. Molecular formula: C6F14. Mole weight: 338.04. EINECS: 206-585-0. InChIKey: ZJIJAJXFLBMLCK-UHFFFAOYSA-N. Appearance: Colorless liquid. | |
| Perflubron | Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography. Category: Active pharmaceutical ingredients. CAS No. 423-55-2. Product ID: API423552. Molecular formula: C8BrF17. Mole weight: 498.96. | |
| Perfluorhexyloctane | Perfluorohexyloctane is indicated for the treatment of the signs and symptoms of dry eye disease. Category: Active pharmaceutical ingredients. Synonyms: 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluorotetradecane, 1-(Tridecafluorohex-1-yl)octane. CAS No. 133331-77-8. Product ID: API133331778. Molecular formula: C14H17F13. Mole weight: 432.269. | |
| Perindopril Erbumine | Perindopril erbumine is a long - acting angiotensin - converting enzyme (ACE) inhibitor formulated as the tert - butylamine salt for improved stability and absorption. It is a prodrug that requires hepatic hydrolysis to its active diacid metabolite, perindoprilat. Applications: Perindopril is indicated for essential hypertension, stable coronary artery disease (reducing cardiovascular events), and heart failure. in the europa trial, perindopril reduced major adverse cardiac events in patients with stable coronary artery disease. it is also used for diabetic nephropathy to slow renal progression. Category: Active pharmaceutical ingredients. Synonyms: ACEON; Perindopril tert-butylamine; McN-A-2833-109; S-9490-3; NSC-758929; DTXSID1044198. CAS No. 107133-36-8. Product ID: API0231634. Molecular formula: C23H43N3O5. Mole weight: 441.6. EINECS: 600-798-6. InChIKey: IYNMDWMQHSMDDE-MHXJNQAMSA-N. Appearance: White to off-white crystalline powder. | |
| Pexidartinib | Pexidartinib (PLX-3397) is a capsule containing a small-molecule receptor tyrosine kinase (RTK) inhibitor targeting KIT, CSF1R, and FLT3, with potential antineoplastic activity. Category: Active pharmaceutical ingredients. CAS No. 1029044-16-3. Product ID: API1029044163. Molecular formula: C20H15ClF3N5. Mole weight: 417.81. | |
| Pexidartinib hydrochloride | Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally active, ATP-competitive inhibitor of colony-stimulating factor 1 (CSF1R or M-CSFR) (IC50: 20 nM) and c-Kit (IC50: 10 nM), with 10-100 times greater selectivity for these targets compared to FLT3 (IC50: 160 nM), KDR (VEGFR2) (IC50: 350 nM), and LCK (IC50: 860 nM). Pexidartinib hydrochloride induces apoptosis and exhibits anti-tumor effects. Category: Active pharmaceutical ingredients. CAS No. 2040295-03-0. Product ID: API2040295030. Molecular formula: C20H16Cl2F3N5. Mole weight: 454.28. | |
| PF-06463922 acetate | PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non-small cell lung cancer (NSCLC). Category: Active pharmaceutical ingredients. CAS No. 1924207-18-0. Product ID: API1924207180. Molecular formula: C23H23FN6O4. Mole weight: 466.4734. | |
| PfDHODH-IN-1 | PfDHODH-IN-1, an analogue of the active Leflunomide metabolite, exhibits antimalarial activity. Category: Active pharmaceutical ingredients. CAS No. 183945-55-3. Product ID: API183945553. Molecular formula: C14H11F3N2O2. Mole weight: 296.24. | |
| Phenmetrazine Hydrochloride | Phenmetrazine Hydrochloride is a sympathomimetic amine and central nervous system stimulant belonging to the morpholine class. Its morpholine ring system structurally differentiates it from phenethylamine-class stimulants such as amphetamine. Applications: Used as a central nervous system stimulant. phenmetrazine hydrochloride is a morpholine-class sympathomimetic amine that was historically indicated for the short-term management of obesity and narcolepsy. its morpholine ring structure differentiates it from phenethylamine-class stimulants in pharmacological profile. Category: Active pharmaceutical ingredients. Synonyms: 3-Methyl-2-phenylmorpholine hydrochloride. CAS No. 1707-14-8. Product ID: API1707148. Molecular formula: C11H16ClNO. Mole weight: 213.7. InChIKey: VJNXVAVKCZJOFQ-UHFFFAOYSA-N. Appearance: Solid. | |
| Phenylbutazone | Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) belonging to the pyrazolidine class. It was one of the earliest synthetic anti-inflammatory agents developed and is characterized by its potent anti-inflammatory effects and significant toxicity profile. Applications: In human medicine, its use is largely restricted to the management of ankylosing spondylitis and acute exacerbations of gout where other agents have failed. it is reserved for second-line therapy due to the high incidence of life-threatening adverse effects, including aplastic anemia and agranulocytosis. it is more commonly used in veterinary medicine, particularly in equine practice. Category: Nonsteroidal anti-inflammatory (nsaid) apis. Synonyms: Benzone; Betazed; bizolin; Phenylbutazone; PHENYLBUTAZONE; 1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione. CAS No. 50-33-9. Product ID: API50339. Molecular formula: C19H20N2O2. Mole weight: 308.37. EINECS: 200-029-0. InChIKey: VYMDGNCVAMGZFE-UHFFFAOYSA-N. Appearance: White to off-white powder. | |
| Phenylephrine Hydrochloride | Phenylephrine hydrochloride is a direct - acting synthetic sympathomimetic amine that selectively activates alpha - 1 adrenergic receptors. It is widely available as an oral decongestant, an ophthalmic solution for pupil dilation, and as a parenteral agent for managing hypotension. The drug has no significant beta - adrenergic activity, making it distinct from ephedrine. Applications: Oral phenylephrine is used as a nonprescription decongestant for sinus congestion and allergic rhinitis, though its oral bioavailability is low (about 38%), limiting efficacy. ophthalmic phenylephrine (2.5% or 10%) is indicated for fundoscopic examination and preoperative mydriasis. intravenous phenylephrine is a first - line agent for treating hypotension during anesthesia or shock. Category: Active pharmaceutical ingredients. Synonyms: Phenylephrine HCl; Mydfrin; Nostril; (R)-Phenylephrine hydrochloride; Neo-Synephrine; L-PHENYLEPHRINE HYDROCHLORIDE; Almefrin. CAS No. 61-76-7. Product ID: API0231630. Molecular formula: C9H14ClNO2. Mole weight: 203.66. EINECS: 200-517-3. InChIKey: OCYSGIYOVXAGKQ-FVGYRXGTSA-N. Appearance: White to off-white crystalline powder. | |
| Phloroglucinol Dihydrate | 1,3,5-Trihydroxybenzene dihydrate (CAS# 6099-90-7) is a reactant used in the synthesis of [2-13C, 4-13C]-(2R,3S)-catechin and [2-13C, 4-13C]-(2R,3R)-epicatechin. Category: Active pharmaceutical ingredients. Synonyms: benzene-1,3,5-triol dihydrate. 1,3,5-Trihydroxybenzene dihydrate. 1,3,5-Benzenetriol, dihydrate. CAS No. 6099-90-7. Product ID: API6099907. Molecular formula: C6H10O5. Mole weight: 162.14. SMILES: C1=C(C=C(C=C1O)O)O.O.O. Appearance: Off-white powder. | |
| Phosphatidylserine | 1,2-distearoyl-sn-glycero-3-phosphoserine is a 3-sn-phosphatidyl L-serine in which the phosphatidyl acyl group at both positions 1 and 2 is stearoyl. It has a role as a mouse metabolite. It is functionally related to an octadecanoic acid. Applications: Ingredient of health care products. Category: Natural extract. Synonyms: Distearoylphosphatidylserine. Phosphatidylserine. Phosphotidylserine. 1,2-dioctadecanoyl-sn-glycero-3-phosphoserine. CAS No. 51446-62-9. Product ID: PIPE-0761. Molecular formula: C42H82NO10P. Mole weight: 792.1. SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(C(=O)O)N)OC(=O)CCCCCCCCCCCCCCCCC. Appearance: Solid powder. | |
| Phthalylsulfathiazole | Phthalylsulfathiazole is a kind of sulfonamides used as an antibacterial drug. Category: Active pharmaceutical ingredients. CAS No. 85-73-4. Product ID: API85734. Molecular formula: C17H13N3O5S2. Mole weight: 403.43. Appearance: Crystalline. | |
| Phycocyanin | Phycocyanin is a natural pigment-protein complex extracted from blue-green algae, scientifically known as Arthrospira platensis. Phycocyanin is one of a family of water-soluble proteins and is distinct in its construction as well as its function as a primary light-harvesting photosynthetic pigment. Commercially, phycocyanin is used in the biomedical and diagnostic arena as an ultra-high purity biological fluorophore and an investigational therapeutic intermediate. Applications: Phycocyanin is used widely in the development of investigational therapeutic products geared towards the treatment of chronic inflammation and oxidative stress. industries focused on diagnostics utilize phycocyanin in the manufacture of fluorescent probes and labels for laboratory assays. phycocyanin is also used as a specialty ingredient in pharmaceutical-grade nutraceuticals as well as premium cosmetic formulations. Category: Natural extract. Synonyms: PE-CY; Phycocyanin E25. Product ID: PIPE-0321. Appearance: Powder. | |
| Pilocarpine | Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. Category: Other apis. Synonyms: Pilokarpin. Pilocarpol. Syncarpine. CAS No. 92-13-7. Product ID: API92137. Molecular formula: C11H16N2O2. Mole weight: 208.26. EINECS: 202-128-4. SMILES: CCC1C(COC1=O)CC2=CN=CN2C. Appearance: OIL OR CRYSTALS. | |
| Pilocarpine Hydrochloride | Pilocarpine hydrochloride is a natural alkaloid muscarinic receptor agonist used to treat dry mouth (xerostomia) and dry eyes. It is available as oral tablets for systemic use and as ophthalmic solutions for topical application. The drug has a short duration of action and requires multiple daily dosing. Applications: Oral pilocarpine is indicated for xerostomia due to sjögren's syndrome or radiation therapy for head and neck cancer. ophthalmic pilocarpine is used for primary open-angle glaucoma, ocular hypertension, and acute angle-closure glaucoma (emergency miosis). it is also employed to reverse mydriasis after ocular examination. Category: Active pharmaceutical ingredients. Synonyms: Pilocarpine HCl; Salagen; Pilocarpine monohydrochloride; Sno pilo; Isopto carpine; Vistacarpin N. CAS No. 54-71-7. Product ID: API0231624. Molecular formula: C11H17ClN2O2. Mole weight: 244.72. EINECS: 200-212-5. InChIKey: RNAICSBVACLLGM-GNAZCLTHSA-N. Appearance: White to off-white crystalline powder. | |
| Pimavanserin | Pimavanserin (ACP-103)(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-based functional assay). Pimavanserin is an atypical antipsychotic used in the treatment of hallucinations and psychosis in patients with Parkinson disease. Category: Active pharmaceutical ingredients. CAS No. 706779-91-1. Product ID: API706779911. Molecular formula: C25H34FN3O2. Mole weight: 427.55. | |
| Pimavanserin tartrate | Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis, with the most potent inhibitory activity on the NFAT signaling pathway. Category: Active pharmaceutical ingredients. Synonyms: ACP-103. CAS No. 706782-28-7. Product ID: API706782287. Molecular formula: C50H68F2N6O4·C4H6O6. Mole weight: 1005.2. | |
| Pimodivir HCl | Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex.The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay. VX-787 is active against a diverse. Category: Active pharmaceutical ingredients. CAS No. 1777721-70-6. Product ID: API1777721706. Molecular formula: C20H19F2N5O2ClH·1/2H2O. Mole weight: 444.86. | |
| Pimodivir tosylate | Pimodivir, also known as VX-787, JNJ-872,is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of the PB2 subunit with a KD (dissociation constant) of 24 nM as determined by isothermal titration calorimetry (ITC). Category: Active pharmaceutical ingredients. CAS No. 1777814-27-3. Product ID: API1777814273. Molecular formula: C27H27F2N5O5S. Mole weight: 571.6. | |
| PimodivirVX-787 | Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit. Category: Active pharmaceutical ingredients. CAS No. 1629869-44-8. Product ID: API1629869448. Molecular formula: C20H19F2N5O2. Mole weight: 399.39. | |
| Pimozide | Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of the motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors. Category: Active pharmaceutical ingredients. Synonyms: R6238. CAS No. 2062-78-4. Product ID: API2062784. Molecular formula: C28H29F2N3O. Mole weight: 461.55. | |
| Pimozide-d4 | Pimozide D4 is a deuterium labeled Pimozide. Category: Active pharmaceutical ingredients. CAS No. 1803193-57-8. Product ID: API1803193578. Molecular formula: C28H29F2N3O. Mole weight: 465.57. | |
| Pinacidil | Pinacidil is a cyanoguanidine derivative that functions as a potassium channel opener, primarily investigated for the treatment of hypertension. It is an oral vasodilator that was developed in the 1980s but never gained widespread approval in the United States. The drug acts on ATP-sensitive potassium channels in vascular smooth muscle. Applications: Although not fda-approved, pinacidil has been used in other countries as an antihypertensive agent, particularly as add-on therapy when beta-blockers or diuretics are insufficient. the drug's lack of selectivity for vascular versus pancreatic katp channels can also stimulate insulin release, causing hypoglycemia in susceptible individuals. Category: Active pharmaceutical ingredients. Synonyms: Pinacidil hydrate; DTXSID4045682; 7B0ZZH8P2W; NSC-759588; DTXCID2025682; Pinacidilum. CAS No. 85371-64-8. Product ID: API0231594. Molecular formula: C13H21N5O. Mole weight: 263.34. EINECS: 262-294-9. InChIKey: AFJCNBBHEVLGCZ-UHFFFAOYSA-N. Appearance: White powder. | |
| Pipamperone | Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor. Category: Active pharmaceutical ingredients. CAS No. 1893-33-0. Product ID: API1893330. Molecular formula: C21H30FN3O2. Mole weight: 375.48. | |
| Pipamperone HCl | Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. Category: Active pharmaceutical ingredients. CAS No. 2448-68-2. Product ID: API2448682. Molecular formula: C21H31ClFN3O2. Mole weight: 411.95. | |
| Pirbuterol Acetate | Pirbuterol Acetate is a selective beta-2 adrenergic receptor agonist bronchodilator with a unique pyridine heterocyclic structure. Unlike traditional catecholamine derivatives, its non-catechol structure confers resistance to COMT-mediated degradation, providing a longer duration of action and allowing oral administration in addition to inhalation. The acetate salt is used in inhalation aerosol formulations. Applications: Pirbuterol acetate is indicated for the prevention and reversal of bronchospasm in patients with asthma, copd, and other reversible obstructive airway diseases. Category: Active pharmaceutical ingredients. Synonyms: 2-(HYDROXYMETHYL)-6-(1-HYDROXY-2-TERT-BUTYLAMINO-ETHYL)-PYRIDIN-3-OL. CAS No. 65652-44-0. Product ID: API65652440. Molecular formula: C14H24N2O5. Mole weight: 300.35. InChIKey: QSXMZJGGEWYVCN-UHFFFAOYSA-N. Appearance: White to off-white solid. | |
| Pirtobrutinib | Pirtobrutinib is a kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy. Category: Active pharmaceutical ingredients. Synonyms: (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole-4-carboxamide. 1h-pyrazole-4-carboxamide, 5-amino-3-(4-(((5-fluoro-2-methoxybenzoyl)amino)methyl)phenyl)-1-((1s)-2,2,2-trifluoro-1-methylethyl)-. 5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-((2s)-1,1,1-trifluoropropan-2-yl)-1h-pyrazole-4-carboxamide; LOXO-305. CAS No. 2101700-15-4. Product ID: API2101700154. Molecular formula: C22H21F4N5O3. Mole weight: 479.436. | |
| Pitavastatin calcium | Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions. Category: Active pharmaceutical ingredients. Synonyms: NK-104 hemicalcium, Pitavastatin hemicalcium, P-872441. CAS No. 147526-32-7. Product ID: API147526327. Molecular formula: C50H46CaF2N2O8. Mole weight: 880.98. | |
| Plx-4032 | Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma. Category: Active pharmaceutical ingredients. CAS No. 1029872-54-5. Product ID: API1029872545. Molecular formula: C23H18ClF2N3O3S. Mole weight: 489.92. | |
| PNU-100440 | PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid. Category: Active pharmaceutical ingredients. CAS No. 168828-82-8. Product ID: API168828828. Molecular formula: C14H17FN2O4. Mole weight: 296.29. | |
| PNU 142300 | PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic linezolid. Category: Active pharmaceutical ingredients. CAS No. 368891-69-4. Product ID: API368891694. Molecular formula: C16H20FN3O6. Mole weight: 369.349. | |
| Polaprezinc | Polaprezinc contains the active ingredient zinc L-carnosine. It is primarily used for its gastroprotective and antioxidant properties. Polaprezinc is indicated for the treatment of gastric ulcers, duodenal ulcers, and gastritis. It works by promoting the repair of damaged gastric mucosa, reducing inflammation, and suppressing the activity of Helicobacter pylori, a bacterium associated with gastric ulcers. Category: Active pharmaceutical ingredients. CAS No. 107667-60-7. Product ID: API107667607. Molecular formula: C9H11N4O3Zn. Mole weight: 288.59. Standard: JP. | |
| Polmacoxib | Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Category: Active pharmaceutical ingredients. CAS No. 301692-76-2. Product ID: API301692762. Molecular formula: C18H16FNO4S. Mole weight: 361.39. | |
| Poloppin | Poloppin is a protein-protein interactions modulator of the mitotic polo-like kinases that acts by targeting mutant KRAS. It works synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells. Category: Active pharmaceutical ingredients. CAS No. 683808-78-8. Product ID: API683808788. Molecular formula: C20H15BrF3NO2. Mole weight: 438.24. | |
| Polydextrose | Polydextrose is used as a filler in food, and has texturizing and humectant properties. During the tablet pressing process, polydextrose solution is used as a binder in wet granulation, and also in the production of direct compression tablets. Polydextrose solution can also be used in combination with other materials as a film and tablet coating agent. Category: Chemicals. Synonyms: ISOMALTOSE. 499-40-1. melibiose. D-Isomaltose. CAS No. 68424-04-4. Product ID: CHE68424044. Molecular formula: C12H22O11. Mole weight: 342.3. EINECS: 207-879-1. SMILES: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)O)O)O)O)O)O)O)O. Appearance: White to Off-white Solid. | |
| Poly(ethyl vinyl ether) | Poly(ethyl vinyl ether) can used as a plasticiser for cellulose nitrate and cellulose resin lacquers, as a base for pressure-sensitive adhesives in films and tapes, especially in surgical applications. Category: Chemicals. Synonyms: Vinyl Ethyl Ether Resin (Low M.Wt.);VinylethylethereesinHighMWt;Poly(vinyl ethyl ether), low molecular weight;5-ethyl-5-(6-oxo-1-cyclohexen-1-yl)-barbituric acid;POLY(VINYL ETHYL ETHER);POLY(ETHYL VINYL ETHER);VINYL ETHYL ETHER RESIN;5-(3or6-oxo-1-cyclohexen-1-yl)-5-ethylbarbituricacid. CAS No. 25104-37-4. Product ID: CHE25104374. Molecular formula: C4H8O. Mole weight: 72.11. EINECS: 680-545-4. | |
| Polylactic acid | A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. Category: Capsule excipients. Synonyms: lactic acid. 2-hydroxypropanoic acid. DL-Lactic acid. 2-hydroxypropionic acid. CAS No. 26100-51-6. Product ID: PIE-0299. Molecular formula: C3H6O3. Mole weight: 90.08. EINECS: 200-018-0. SMILES: CC(C(=O)O)O. Appearance: colorless to yellow odorless syrupy liquid. Standard: USP, Ph.Eur. | |
| Poly(methylhydrosiloxane) | Poly(methylhydrosiloxane), a multi-functional, high molecular weight silicone compound, is a colorless, free-flowing liquid with a unique combination of favorable properties: it is non-toxic, physiologically inert, and highly stable in hydrocarbon solvents. Poly(methylhydrosiloxane) has found applications as a green, low-cost, and safe alternative to toxic silanes in the fields of industrial surface modification and complex organic synthesis. Applications: Poly(methylhydrosiloxane) is a green reductant for the reduction of esters to alcohols, phosphine oxides to phosphines, and for the reductive amination to prepare amines. in addition, it is used in industrial material science as the precursor to waterproof membranes, water-repellent and anti-fouling coatings for textiles, ceramics, glass, natural stone, and as an anti-yellowing agent for heat vulcanized silicone rubber. it is also a key ingredient in the production of mold release agents, as a stabilizer of polyurethane foam, and as a moisture-proof treatment for building materials. Category: Solvents. Synonyms: hydroxy(dimethyl)silane,hydroxy(trimethyl)silane,tetramethylsilane. CAS No. 63148-57-2. Product ID: CHE63148572. Molecular formula: (CH4OSi)n. Mole weight: 1700-3200. EINECS: 613-152-3. InChIKey: QNWOFLWXQGHSRH-UHFFFAOYSA-N. Standard: REACH. | |
| Polyquaternium-11 | Polyquaternium-11. Applications: Polyquaternium-11(pq-11) is a quaternary ammonium compound that forms flexible films with mild conditioning benefits in rinse off and styling applications. use as a conditioning agent in shampoos and cream or clear rinse conditioners. pq-11 is compatible with with non-ionic, anionic and amphoteric surfactants and rheology modifiers. pq-11 is excellent combined with carbomer to produce smooth and e. Category: Pharmaceutical excipients. Synonyms: 2-Propenoic acid, 2-methyl-, 2-(dimethylamino)ethyl ester, polymer with 1-ethenyl-2-pyrrolidinone, compd. with diethyl sulfate;poly[(2-ethyldimethylammonioethyl methacrylate ethyl sulfate)-co-(1-vinylpyrrolidone)];2-Propenoic acid, 2-methyl-, 2-(dimethylamino) ethyl ester, polymer with 1-ethenyl-2-pyrrolidinone, compd. with diethyl sulfate yl-2-pyrrolidinone, compd. with diethyl sulfate poly(1-vin. CAS No. 53633-54-8. Product ID: PIE-0063. Molecular formula: C42H72N6O9X2. Mole weight: 805.06. Appearance: Colorless to light yellow viscous liquid. | |
| Polythiazide | Polythiazide (NSC-108161, P-2525) is used to treat fluid retention (edema) caused by a variety of causes, including congestive heart failure, severe liver disease (cirrhosis), kidney disease, or steroid or hormonal medication. Category: Active pharmaceutical ingredients. Synonyms: NSC 108161,P-2525. CAS No. 346-18-9. Product ID: API346189. Molecular formula: C11H13ClF3N3O4S3. Mole weight: 439.88. | |
| PonatiLink-1-24 | Ponatinib, also known as PonatiLink-1-24, is a selective inhibitor of the Abelson murine leukemia (ABL) enzyme. Category: Active pharmaceutical ingredients. CAS No. 2941512-45-2. Product ID: API2941512452. Molecular formula: C101H144ClF5N12O29. Mole weight: 2120.73. | |
| Ponatinib | Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor with IC50 values of 0.37 nM (Abl), 1.1 nM (PDGFRα), 1.5 nM (VEGFR2), 2.2 nM (FGFR1), and 5.4 nM (Src). Category: Active pharmaceutical ingredients. CAS No. 943319-70-8. Product ID: API943319708. Molecular formula: C29H27F3N6O. Mole weight: 532.56. | |
| Ponatinib-d8 | Ponatinib D8 is a deuterium labeled Ponatinib. Ponatinib is an orally active inhibitor of multi-targeted kinase(Abl, PDGFRα, VEGFR2, FGFR1, and Src with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM, respectively). Category: Active pharmaceutical ingredients. CAS No. 1562993-37-6. Product ID: API1562993376. Molecular formula: C29H27F3N6O. Mole weight: 540.61. | |
| Ponatinib Hydrochloride | Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively. Category: Active pharmaceutical ingredients. Synonyms: AP24534 Hydrochloride, AP 24534, AP-24534 Hydrochloride, Ponatinib hydrochloride. Grades: USDMF/HC MF. CAS No. 1114544-31-8. Product ID: API1114544318. Molecular formula: C29H28ClF3N6O. Mole weight: 569.02. Standard: Facility GMP. | |
| Posaconazole-D5 | Posaconazole-D5, a deuterium-labeled variant of Posaconazole, is a second-generation, broad-spectrum triazole compound with antifungal activity. Category: Active pharmaceutical ingredients. Synonyms: SCH 56592-D5. CAS No. 1217785-83-5. Product ID: API1217785835. Molecular formula: C37H42F2N8O4. Mole weight: 705.81. | |
| Posaconazole hydrate | Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole is a sterol C14? demethylase inhibitor (IC50: 0.25 nM). Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Category: Active pharmaceutical ingredients. CAS No. 1198769-38-8. Product ID: API1198769388. Molecular formula: C37H44F2N8O5. Mole weight: 718.79. | |
| Potassium Aminosalicylate | Potassium Aminosalicylate is the potassium salt of 4-aminosalicylic acid (para-aminosalicylic acid, PAS), an antitubercular compound structurally related to para-aminobenzoic acid (PABA). The potassium salt form provides improved water solubility compared to the free acid. Applications: Indicated for the treatment of tuberculosis as a second-line antitubercular agent. potassium aminosalicylate inhibits mycobacterial folate biosynthesis by competing with paba at dihydropteroate synthase, disrupting essential folate-dependent metabolic pathways in mycobacterium tuberculosis. Category: Active pharmaceutical ingredients. Synonyms: potassium 4-aminosalicylate;4-Aminosalicylic acid potassium. CAS No. 133-09-5. Product ID: API133095. Molecular formula: C7H6KNO3. Mole weight: 191.23. EINECS: 205-090-7. InChIKey: PRZJIMSXCLZGLT-UHFFFAOYSA-M. | |
| Potassium Citrate | Potassium Citrate is an alkalinizing salt of potassium and citric acid, used both as a potassium supplement and as a urinary alkalinizing agent. The citrate anion is metabolized in the hepatic TCA cycle to bicarbonate, providing a systemic alkalinizing effect, while potassium is distributed primarily in the intracellular compartment as an essential electrolyte. This dual-action formulation offers advantages over potassium chloride in patients with concurrent metabolic acidosis. Applications: Potassium citrate is indicated for the prevention and treatment of calcium kidney stones (particularly uric acid and calcium oxalate stones) by raising urinary ph and increasing urinary citrate levels. it is also used as a potassium supplement in the treatment and prevention of hypokalemia, particularly when accompanied by metabolic acidosis or when alkalinization is desired. extended-release tablet formulations minimize gastrointestinal irritation. Category: Active pharmaceutical ingredients. Synonyms: Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate;tripotassium citrate anhydrous. CAS No. 866-84-2. Product ID: API866842. Molecular formula: C6H9KO7. Mole weight: 232.23. EINECS: 212-755-5. InChIKey: JOSYFFAWJFRGHM-UHFFFAOYSA-N. | |
| Potassium Phosphate Dibasic | Potassium Phosphate Dibasic (also known as dipotassium hydrogen phosphate or K2HPO4) is an inorganic phosphate salt providing both potassium and phosphate ions in a physiologically balanced ratio. As a pharmaceutical-grade reagent and active ingredient, it is used in nutritional formulations, parenteral fluids, and as a buffering agent in pharmaceutical preparations requiring phosphate-based buffer systems. Applications: Potassium phosphate dibasic is used as a potassium and phosphate supplement in the treatment and prevention of hypokalemia and hypophosphatemia, particularly in patients receiving parenteral nutrition or those with renal tubular acidosis. it is also a component of buffered pharmaceutical formulations and is used in hemodialysis fluids. Category: Active pharmaceutical ingredients. Synonyms: Di-Potassium hydrogen orthophosphate anhydrous. CAS No. 7758-11-4. Product ID: API7758114. Molecular formula: HK2O4P. Mole weight: 174.176. EINECS: 231-834-5. InChIKey: ZPWVASYFFYYZEW-UHFFFAOYSA-L. Appearance: White solid. | |
| Pralsetinib | Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion). Category: Active pharmaceutical ingredients. CAS No. 2097132-94-8. Product ID: API2097132948. Molecular formula: C27H32FN9O2. Mole weight: 533.6. | |
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