Protheragen - Products
Protheragen provides active pharmaceutical ingredients (APIs), chemicals, natural extracts, intermediates, pharmaceutical excipients, and veterinary chemicals
| Product | Description | |
|---|---|---|
| Halobetasol | Halobetasol (Ulobetasol), a corticosteroid, is utilized in the research of severe localized psoriasis. Category: Active pharmaceutical ingredients. CAS No. 98651-66-2. Product ID: API98651662. Molecular formula: C22H27ClF2O4. Mole weight: 428.9. |  |
| Halobetasol propionate | Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Category: Active pharmaceutical ingredients. Synonyms: Halobetasol Propionate, Ulobetasol propionate, BMY-30056, CGP-14458. CAS No. 66852-54-8. Product ID: API66852548. Molecular formula: C25H31ClF2O5. Mole weight: 484.96. | |
| Halofantrine | Halofantrine is an antimalarial active substance that is highly lipophilic and has a blocking effect on HERG potassium channels against the Chloroquine resistant Plasmodium falciparum. Category: Active pharmaceutical ingredients. CAS No. 69756-53-2. Product ID: API69756532. Molecular formula: C26H30Cl2F3NO. Mole weight: 500.42. | |
| Halofantrine hydrochloride | Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent. Category: Active pharmaceutical ingredients. CAS No. 36167-63-2. Product ID: API36167632. Molecular formula: C26H31Cl3F3NO. Mole weight: 536.89. | |
| Halometasone | Halometasone is a synthetic corticosteroid.1,2Formulations containing halometasone have been used in the treatment of psoriasis vulgaris and eczematous dermatoses. Category: Active pharmaceutical ingredients. CAS No. 50629-82-8. Product ID: API50629828. Molecular formula: C22H27ClF2O5. Mole weight: 444.9. | |
| Haloperidol | Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-fold efficacy than chlorpromazine, another antipsychotic drug. Category: Active pharmaceutical ingredients. CAS No. 52-86-8. Product ID: API52868. Molecular formula: C21H23ClFNO2. Mole weight: 375.86. | |
| Haloperidol D4 | Haloperidol D4 is deuterium-labeled haloperidol. Category: Active pharmaceutical ingredients. CAS No. 1189986-59-1. Product ID: API1189986591. Molecular formula: C21H23ClFNO2. Mole weight: 379.89. | |
| Haloperidol (D4\') | Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist. Category: Active pharmaceutical ingredients. CAS No. 136765-35-0. Product ID: API136765350. Molecular formula: C21H23ClFNO2. Mole weight: 379.89. | |
| Haloperidol decanoate | Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection. Category: Active pharmaceutical ingredients. CAS No. 74050-97-8. Product ID: API74050978. Molecular formula: C31H41ClFNO3. Mole weight: 530.11. | |
| Haloperidol hydrochloride | Haloperidol hydrochloride, a potent dopamine D2 receptor antagonist, is an effective antipsychotic agent. Category: Active pharmaceutical ingredients. CAS No. 1511-16-6. Product ID: API1511166. Molecular formula: C21H24Cl2FNO2. Mole weight: 412.33. | |
| Haloperidol lactate | Haloperidol lactate is a potent antipsychotic. haloperidol lactate has potential for studies in psychiatric disorders. haloperidol lactate can be used in acute and chronic schizophrenia and polyarousal syndrome. Category: Active pharmaceutical ingredients. CAS No. 53515-91-6. Product ID: API53515916. Molecular formula: C24H29ClFNO5. Mole weight: 465.95. | |
| HalothaneNarcotane, Anestan | Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. Category: Active pharmaceutical ingredients. CAS No. 151-67-7. Product ID: API151677. Molecular formula: C2HBrClF3. Mole weight: 197.38. | |
| Halquinol | Halquinol. Category: Active pharmaceutical ingredients. CAS No. 8067-69-4. Product ID: API8067694. Molecular formula: C27H17Cl4N3O3. Mole weight: 573.254. Standard: BP. | |
| Hesperetin | It has a role as an antioxidant, an antineoplastic agent and a plant metabolite. It is a monomethoxyflavanone, a trihydroxyflavanone, a member of 3'-hydroxyflavanones and a member of 4'-methoxyflavanones. It is a conjugate acid of a hesperetin(1-). Applications: Ingredient of health care products. Category: Natural extract. Synonyms: 3',5,7-Trihydroxy-4'-methoxyflavanone. (-)-hesperetin. CAS No. 520-33-2. Product ID: PIPE-0667. Molecular formula: C16H14O6. Mole weight: 302.28. EINECS: 208-290-2. SMILES: COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O)O. Appearance: Pale Yellow Solid. | |
| Hexafluoro | Hexafluoro is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrates activity in Vemurafenib-resistant melanoma in vivo. Category: Active pharmaceutical ingredients. CAS No. 128481-73-2. Product ID: API128481732. Molecular formula: C21H18F6O2. Mole weight: 416.36. | |
| Hidrosmin | Hidrosmin, a derivative of Diosmin , is a semisynthetic drug and a member of the flavonoid family. lt is used for the treatment of venous diseases. Category: Natural extract. Synonyms: 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-a-L-Mannopyranosyl)-b-D-glucopyranosyl]oxy]-5-(2-hydroxyethoxy)-2-(3-hydroxy-4-Methoxyphenyl)-;5-(2-hydroxyethoxy)-2-Chemicalbook(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one. CAS No. 115960-14-0. Product ID: PIPE-0401. Molecular formula: C30H36O16. Mole weight: 652.6. Appearance: Powder. | |
| HPMC | Hydroxypropyl methylcellulose (HPMC) is a semisynthetic, inert, viscoelastic polymer of cellulose. Cellulose is alkali-treated then reacted with propylene oxide and methyl chloride to produce hydroxypropyl methylcellulose. Hydroxypropyl substitution increases water solubility, thermal gelation and film-forming properties. HPMC is non-ionic and displays reversible thermal gelation. HPMC can have a low, medium or high viscosity based on molecular weight and degree of substitution. Applications: Applications of hpmc include its use as a binder, disintegrant and controlled release matrix component of tablets in the pharmaceutical industry; it is also used in vegetarian capsules and solutions for eye medications. used as an ingredient in construction materials such as tile adhesive and self-leveling cement, it imparts water retention, workability, and adhesion characteristics. it is used in the food industry as a thickener/emulsifier/stabilizer in sauces, baked goods and meat substitutes. hpmc can also be used in cosmetics as a viscosity control agent and film former for shampoo, lotion, and makeup. Category: Cellulose series. CAS No. 9004-65-3. Product ID: PIE-0230. Appearance: White powder. | |
| HRX-0233 | HRX-0233 is a small molecule inhibitor targeting MAP2K4. In vivo, HRX-0233 effectively reduces tumors in H358 KRASG12C mutant non-small cell lung cancer (NSCLC) without significant toxicity. Category: Active pharmaceutical ingredients. CAS No. 2409140-12-9. Product ID: API2409140129. Molecular formula: C24H21F2N5O3S. Mole weight: 497.52. | |
| Hyaluronic Acid | Hyaluronic acid (HA) is an unbranched glycosaminoglycan (GAG) polymer with an unusually high molecular weight (up to 108 Da) present in vertebrate tissues. The HA polymer is composed of repeating disaccharide units of N-acetyl-d-glucosamine and d-glucuronic acid joined through β-1,4-linkages. Intrachain β-1,3-linkages stabilize HA by placing bulky substituent groups equatorially with hydrogen atoms axially minimizing rotation. Alternating hydrophobic/hydrophilic surfaces result, which are held together by hydrogen bonding. In neutral solutions, HA becomes anionic as carboxyl groups dissociate. The resulting salts of hyaluronan with Na+ or Ca2+ give HA exceptional hydrophilicity. Once hydrated, the rigid HA secondary structure predominates as a left-handed helix. HA tends to form duplexes in solution by intermolecular hydrogen bonding and hydrophobic interactions, which further collapse the structure into a β-sheet tertiary structure forming an extended polymeric mesh. Applications: Hyaluronic acid (ha) is a multifunctional biopolymer utilized across diverse industries due to its exceptional biocompatibility and moisture-retention properties. in aesthetic medicine and skincare, it serves as the gold standard for dermal fillers to restore facial volume and as a premier humectant in topical formulations to enhance skin hydration and elasticity. beyond cosmetics, ha plays a c. C | |
| Hydrochlorothiazide | Hydrochlorothiazide is a thiazide-type diuretic and antihypertensive agent widely used for over 60 years. As the most frequently prescribed thiazide diuretic, it is characterized by its reliable efficacy and relatively safe profile for managing hypertension and edema. Applications: Hydrochlorothiazide is fda-approved for treating essential hypertension as primary or adjunctive therapy and for managing peripheral edema associated with heart failure, cirrhosis, corticosteroids, or nephrotic syndrome. Category: Diuretic apis. Synonyms: HCTZ; Esidrix; Hydro-Diuril; Oretic. CAS No. 58-93-5. Product ID: API0233009. Molecular formula: C7H8ClN3O4S2. Mole weight: 297.74. EINECS: 200-403-3. InChIKey: JZUFKLXOESDKRF-UHFFFAOYSA-N. | |
| Hydroflumethiazide | Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive. Category: Active pharmaceutical ingredients. CAS No. 135-09-1. Product ID: API135091. Molecular formula: C8H8F3N3O4S2. Mole weight: 331.29. | |
| Hydromorphone Hydrochloride | Hydromorphone hydrochloride is the hydrochloride salt form of hydromorphone, a semi-synthetic opioid agonist derived from morphine and classified as a Schedule II controlled substance. It is available in multiple formulations including immediate-release and extended-release oral tablets, oral solution, injectable solutions, and rectal suppositories. It is approximately five times more potent than morphine and is characterized by rapid onset and predictable duration of action. Applications: Hydromorphone hydrochloride is indicated for the management of moderate-to-severe acute pain and severe chronic pain requiring around-the-clock opioid therapy in patients for whom alternative treatment options are inadequate. due to significant risks of respiratory depression, addiction, abuse, and neonatal withdrawal syndrome, therapy requires careful patient selection, gradual tapering upon discontinuation, and availability of naloxone for overdose reversal. Category: Anesthetic analgesia apis. Synonyms: Hydromorphone HCl. CAS No. 71-68-1. Product ID: API0232183. Molecular formula: C17H20ClNO3. Mole weight: 321.8. EINECS: 200-762-6. InChIKey: XHILEZUETWRSHC-NRGUFEMZSA-N. Appearance: White or almost white crystalline powder. | |
| Hydrotalcite | an antacid indicated in the treatment of heartburn and excess gastric acid. Category: Active pharmaceutical ingredients. CAS No. 12304-65-3. Product ID: API12304653. Molecular formula: CH30Al2Mg6O23. Mole weight: 619.981. Standard: CP/BP. | |
| Hydroxocobalamin | Hydroxocobalamin is a natural form of vitamin B12 (vitamin B12a) available as a sterile injectable solution for intramuscular or intravenous administration. It appears as a dark red solution and is approved for the treatment of vitamin B12 deficiency and known or suspected cyanide poisoning. Applications: Hydroxocobalamin is indicated for the treatment of pernicious anemia and vitamin b12 deficiency resulting from various causes including malabsorption, alcoholism, and restrictive diets. it is the first-line treatment for cyanide toxicity, particularly in smoke inhalation victims where concomitant carbon monoxide poisoning may be present. Category: Vitamin apis. Synonyms: Cyanokit, Hydroxomin, AlphaRedisol. CAS No. 13422-51-0. Product ID: API0233496. Molecular formula: C62H89CoN13O15P. Mole weight: 1346.4. EINECS: 236-533-2. InChIKey: YOZNUFWCRFCGIH-WZHZPDAFSA-K. | |
| Hydroxy Celecoxib | Hydroxy celecoxib, an inactive metabolite of celecoxib, is synthesized through the metabolism of celecoxib by cytochrome P450 (CYP) isoforms CYP2C9, CYP3A4, and CYP2D6 in human liver microsomes. Category: Active pharmaceutical ingredients. CAS No. 170571-00-3. Product ID: API170571003. Molecular formula: C17H14F3N3O3S. Mole weight: 397.37. | |
| Hydroxyprogesterone Caproate | Hydroxyprogesterone caproate is a synthetic, steroidal progestin; an ester derivative of 17α-hydroxyprogesterone formed from caproic acid. Category: Active pharmaceutical ingredients. CAS No. 630-56-8. Product ID: API630568. Molecular formula: C27H40O4. Mole weight: 428.604. Appearance: Powder. | |
| Hydroxyzine Pamoate | Hydroxyzine Pamoate is the pamoate salt of hydroxyzine, a first-generation histamine H1 receptor antagonist of the piperazine class. It is widely recognized for its anxiolytic, sedative, and antipruritic properties resulting from its central and peripheral H1 receptor blockade. Applications: Indicated for the treatment of anxiety disorders, pruritus, and allergic conditions. hydroxyzine pamoate is a first-generation h1 receptor antagonist used as an anxiolytic, sedative, and antipruritic agent. it is also employed in preoperative sedation, nausea management, and symptomatic relief of chronic urticaria. Category: Active pharmaceutical ingredients. Synonyms: 1-(p-Chloro-α-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine,pamoate;2-Naphthalenecarboxylicacid,4,4'-mChemicalbookethylenebis[3-hydroxy-,compd.with2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol(1:1). CAS No. 10246-75-0. Product ID: API10246750. Molecular formula: C44H43ClN2O8. Mole weight: 763.3. EINECS: 233-582-1. InChIKey: ASDOKGIIKXGMNB-UHFFFAOYSA-N. Appearance: Yellow solid. | |
| Idelalisib D5 | Idelalisib D5, a version of Idelalisib marked with deuterium, is an orally bioavailable and highly selective inhibitor of p110δ. Category: Active pharmaceutical ingredients. Synonyms: CAL-101 D5, GS-1101 D5. CAS No. 1830330-31-8. Product ID: API1830330318. Molecular formula: C22H18FN7O. Mole weight: 420.45. | |
| IDO1-IN-15 | IDO1-IN-15 is an effective IDO1 inhibitor with IC50 of 127 nM. The potency of IDO1-IN-15 against IDO1 enzyme is comparable with Epacadostat in vitro. Category: Active pharmaceutical ingredients. CAS No. 2126853-17-4. Product ID: API2126853174. Molecular formula: C13H14BrFN6O3. Mole weight: 401.19. | |
| Iloperidone | Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. Category: Active pharmaceutical ingredients. CAS No. 133454-47-4. Product ID: API133454474. Molecular formula: C24H27FN2O4. Mole weight: 426.48. | |
| Iloperidone hydrochloride | Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms. Category: Active pharmaceutical ingredients. CAS No. 1299470-39-5. Product ID: API1299470395. Molecular formula: C24H28ClFN2O4. Mole weight: 462.95. | |
| Iloperidone metabolite P95 | Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors with mean Ki values of 7.08, 21.38, 83.18, and 47.86 nM, respectively, but does not cross the blood-brain barrier. Category: Active pharmaceutical ingredients. CAS No. 475110-48-6. Product ID: API475110486. Molecular formula: C23H25FN2O5. Mole weight: 428.46. | |
| Iloprost | A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension. It has a role as a platelet aggregation inhibitor and a vasodilator agent. Category: Active pharmaceutical ingredients. Synonyms: Ciloprost. Ventavis. Endoprost. Ilomedin. CAS No. 78919-13-8. Product ID: API78919138. Molecular formula: C22H32O4. Mole weight: 360.5. EINECS: 636-055-8. SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O. Appearance: Colourless to Pale Yellow Oil to Solid. | |
| Imatinib Mesylate | Imatinib mesylate is a c-Abl, PDGFR, and c-kit inhibitor that halts chronic myelogenous leukemia related growth. Category: Active pharmaceutical ingredients. CAS No. 220127-57-1. Product ID: API220127571. Molecular formula: C29H31N7O CH3SO3H. Mole weight: 589.71. Appearance: Crystalline powder. | |
| imidapril hydrochloride | Imidapril Hydrochloride is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Category: Active pharmaceutical ingredients. CAS No. 89396-94-1. Product ID: API89396941. Molecular formula: C20H28ClN3O6. Mole weight: 441.91. Standard: JP. | |
| Imidocarb | Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Category: Antiparasitic apis. Synonyms: 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea. Imidocarbe. Imidocarbo. CAS No. 27885-92-3. Product ID: API27885923. Molecular formula: C19H20N6O. Mole weight: 348.4. EINECS: 248-711-7. SMILES: C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NC3=CC=CC(=C3)C4=NCCN4. Standard: Company Standard. | |
| IMP-1700 | IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus(MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. Category: Active pharmaceutical ingredients. CAS No. 1458674-25-3. Product ID: API1458674253. Molecular formula: C25H22F4N4O3S. Mole weight: 534.53. | |
| Inavolisib | Inavolisib is a potent, orally active, and selective PI3Kα inhibitor (IC50=0.038 nM). Category: Active pharmaceutical ingredients. Synonyms: GDC-0077; RG6114. CAS No. 2060571-02-8. Product ID: API2060571028. Molecular formula: C18H19F2N5O4. Mole weight: 407.37. InChIKey: SGEUNORSOZVTOL-CABZTGNLSA-N. | |
| Indecainide Hydrochloride | Indecainide hydrochloride is a class Ic antiarrhythmic agent that was developed for the suppression of ventricular arrhythmias. It is a congener of flecainide, with similar sodium channel blocking properties. The drug was never widely marketed and is now of primarily historical interest due to the emergence of safer agents. Applications: Indecainide was investigated for the treatment of life - threatening ventricular arrhythmias, including sustained ventricular tachycardia, in patients who did not respond to class i agents. no current clinical use exists, and the drug serves only as a research tool for understanding sodium channel pharmacology. Category: Active pharmaceutical ingredients. Synonyms: Indecainide HCl; LY 135837; M76V0B96L5; 9H-Fluorene-9-carboxamide, 9-(3-((1-methylethyl)amino)propyl)-, monohydrochloride; LY-135837. CAS No. 73681-12-6. Product ID: API0231632. Molecular formula: C20H25ClN2O. Mole weight: 344.9. InChIKey: NXNSCUZKMVYAJQ-UHFFFAOYSA-N. | |
| Indole-3-carbinol | Indole-3-carbinol. Category: Natural extract. Synonyms: (1H-Indol-3-yl)-methano;3-INDOLAMETHANOL;INDOLE-3-CARBINOL:3-INDOLE METHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL). CAS No. 700-06-1. Product ID: PIPE-0241. Molecular formula: C9H9NO. Mole weight: 147.17. EINECS: 211-836-2. SMILES: N1C2=C(C=CC=C2)C(CO)=C1. InChIKey: IVYPNXXAYMYVSP-UHFFFAOYSA-N. Appearance: Crystalline Powder or Flakes. Standard: In house. | |
| Inositol | Myo-inositol is an inositol having myo- configuration. It has a role as a member of compatible osmolytes, a nutrient, an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor, a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. Category: Other apis. Synonyms: myo-inositol. Scyllo-inositol. epi-Inositol. Muco-Inositol. CAS No. 551-72-4. Product ID: API551724. Molecular formula: C6H12O6. Mole weight: 180.16. EINECS: 201-781-2. SMILES: C1(C(C(C(C(C1O)O)O)O)O)O. Appearance: White crystalline powder. Standard: CP. | |
| Inositol nicotinate | Myo-Inositol hexanicotinate has been used as a niacin source. Although some studies have shown it to reduce levels of serum fatty acids, other studies have shown that there is no reduction of total cholesterol, LDL-C, HDL-C or triglycerides. Inositol niacinate is an nicotinate conjugate of myo-inositol, an structural basis for a number of secondary messengers. Category: Active pharmaceutical ingredients. CAS No. 6556-11-2. Product ID: API6556112. Molecular formula: C42H30N6O12. Mole weight: 810.721. | |
| Iodipamide Sodium | Iodipamide sodium (also known as adipiodone) is an ionic, high - osmolar, tri - iodinated contrast agent specifically developed for intravenous cholangiography and cholecystography. It is administered intravenously, where it is taken up by hepatocytes and excreted into the bile, opacifying the biliary tract. Applications: Iodipamide was indicated for oral cholecystography (when given orally as the calcium salt) and intravenous cholangiography to detect gallstones, biliary obstruction, or bile duct abnormalities. its use has been superseded by endoscopic retrograde cholangiopancreatography (ercp), magnetic resonance cholangiopancreatography (mrcp), and non - ionic ct contrast. Category: Active pharmaceutical ingredients. Synonyms: Cholografin sodium; Iodipamide disodium salt; UNII-3J6WZA9PXS; 3J6WZA9PXS; EINECS 220-049-3. CAS No. 2618-26-0. Product ID: API0231637. Molecular formula: C20H12I6N2Na2O6. Mole weight: 1183.7. EINECS: 220-049-3. InChIKey: SIZXNBZGPPPFHM-UHFFFAOYSA-L. Appearance: White powder. | |
| Iodohippurate Sodium I-123 | Iodohippurate Sodium I-123 (123I-OIH) is a radiopharmaceutical containing the radioisotope iodine-123 (123I) bound to ortho-iodohippuric acid, a derivative of hippuric acid. Iodine-123 is a short-lived gamma-emitting radionuclide (half-life 13.2 hours) ideal for single-photon emission computed tomography (SPECT) imaging. Iodohippurate is efficiently cleared by the kidneys through both glomerular filtration and tubular secretion. Applications: Iodohippurate sodium i-123 is indicated as a diagnostic radiopharmaceutical for the assessment of renal function and anatomy using spect imaging. it is used for the evaluation of renal perfusion, differential renal function, detection of renal artery stenosis, and assessment of renal transplant viability and function. its superior imaging characteristics provide high-quality diagnostic images with minimal radiation exposure to the patient. Category: Active pharmaceutical ingredients. CAS No. 56254-07-0. Product ID: API56254070. Molecular formula: C9H7INNaO3. Mole weight: 323.05. InChIKey: XYITYKDGJLHYPW-TWDNZPFZSA-M. | |
| Iofetamine Hydrochloride I-123 | Iofetamine hydrochloride I-123 (IMP) is a radiopharmaceutical used for single-photon emission computed tomography (SPECT) imaging of regional cerebral blood flow. It is a lipophilic amine that crosses the blood-brain barrier rapidly. Applications: Iofetamine i-123 was indicated for the evaluation of regional cerebral perfusion in patients with suspected stroke, transient ischemic attacks, dementia, and seizure focus localization. it is also used to assess brain death. Category: Active pharmaceutical ingredients. Synonyms: Iofetamine hydrochloride I 123; Spectamine; (sup 123)I-M123; UNII-R5O1XB5L3M; Iofetamine (123 i) hcl; R5O1XB5L3M; Iofetamine i 123 hydrochloride. CAS No. 85068-76-4. Product ID: API0231644. Molecular formula: C12H19ClIN. Mole weight: 335.64. InChIKey: AFLDFEASYWNJGX-FOHXBPHZSA-N. | |
| Iopamidol | Iopamidol. Category: Contrast agent apis. Synonyms: N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide. D-Iopamidol. CAS No. 62883-00-5. Product ID: API62883005. Molecular formula: C17H22I3N3O8. Mole weight: 777.1. EINECS: 262-093-6. SMILES: CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O. Standard: CP,JP,BP,USP,EP. | |
| Iopromide | Iopromide is a water-soluble, non-ionic, monomeric, low-osmolar, iodine-based contrast medium for intravascular administration. Category: Active pharmaceutical ingredients. CAS No. 73334-07-3. Product ID: API73334073. Molecular formula: C18H24I3N3O. Mole weight: 791.112. | |
| Iothalamate Sodium | Iothalamate sodium is an ionic, high-osmolar, tri-iodinated radiographic contrast agent used primarily for urography, angiography, and computed tomography enhancement. It is available as a sterile solution for intravascular, intracavitary, or intrathecal administration, though its use has largely been replaced by low-osmolar and iso-osmolar agents. The compound contains three iodine atoms per molecule, providing excellent radiopacity. Applications: It is indicated for various radiographic procedures including intravenous urography, peripheral arteriography, coronary arteriography, and contrast-enhanced computed tomography. it is also used to measure glomerular filtration rate clinically, as its renal clearance closely approximates inulin clearance. due to the risk of contrast-induced nephropathy and hypersensitivity reactions, including anaphylaxis, its use requires careful patient selection, particularly in those with pre-existing renal impairment or contrast allergy. Category: Other apis. Synonyms: Sodium iothalamate; Angio-Conray; Mediocontrix; Iothalamic acid sodium salt; KDN276D83N; DTXSID1057668; Monosodium 5-acetamido-2,4,6-triiodo-N-methylisophthalamate. CAS No. 1225-20-3. Product ID: API0231564. Molecular formula: C11H8I3N2NaO4. Mole weight: 635.89. EINECS: 214-955-8. InChIKey: WCIMWHNSWLLELS-UHFFFAOYSA-M. | |
| Iotrolan | Iotrolan is a non-ionic, dimeric iodinated contrast medium specifically designed for myelography and cisternography. Unlike conventional intravascular contrast agents, it is formulated for intrathecal use and is characterized by high hydrophilicity, low protein binding, and minimal neurotoxicity. Applications: Used in diagnostic myelography and cisternography for imaging the spinal canal and subarachnoid space. iotrolan is a non-ionic dimeric contrast agent specifically formulated for intrathecal use with high hydrophilicity, near-zero protein binding, and minimal neurotoxicity, providing superior safety for neuroradiological procedures. Category: Active pharmaceutical ingredients. Synonyms: 5,5'-[(1,3-Dioxo-1,3-propanediyl)bis(methylimino)]bis[N,N'-bis[2,3-dihydroxy-1-(hydroxymethyl)propyl]-2,4,6-triiodo-1,3-benzenedicarboxamide];2,4,6-triiodo-5-[methyl-[Chemicalbook3-[methyl-[2,4,6-triiodo-3,5-bis(1,3,4-trihydroxybutan-2-ylcarbamoyl)phenyl]amino]-3-oxo-propanoyl]amino]-N1,N3-bis(1,3,4-trihydroxybutan-2-yl)benzene-1,3-dicarboxamide. CAS No. 79770-24-4. Product ID: API79770244. Molecular formula: C37H48I6N6O18. Mole weight: 1626.2. InChIKey: XUHXFSYUBXNTHU-UHFFFAOYSA-N. | |
| Ioxaglate Meglumine | Ioxaglate Meglumine is an ionic, dimeric iodinated X-ray contrast medium. As a low-osmolality ionic dimer, it occupies a unique position between conventional ionic monomers and non-ionic dimers in the contrast agent spectrum, combining ionic dissociation with a reduced particle-to-iodine ratio. Applications: Used in diagnostic imaging for angiography, urography, and computed tomography (ct). ioxaglate meglumine is a low-osmolality ionic dimeric contrast agent that offers reduced osmotic stress compared to conventional ionic monomers while maintaining ionic dissociation characteristics for optimal radiographic density. Category: Active pharmaceutical ingredients. Synonyms: MEGLUMINE IOXAGLATE. CAS No. 59018-13-2. Product ID: API59018132. Molecular formula: C31H38I6N6O13. Mole weight: 1464.1. InChIKey: HUHDYASLFWQVOL-WZTVWXICSA-N. | |
| Ipragliflozin | Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. Category: Active pharmaceutical ingredients. CAS No. 761423-87-4. Product ID: API761423874. Molecular formula: C21H21FO5S. Mole weight: 404.45. | |
| Ipragliflozin (L-Proline) | Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6. Category: Active pharmaceutical ingredients. CAS No. 951382-34-6. Product ID: API951382346. Molecular formula: C26H30FNO7S. Mole weight: 519.58. | |
| IR-Crizotinib | IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial glioblastoma (GBM) localization in mice. It has the ability to cross the blood-brain barrier and fluorescently mark GBM, and demonstrates efficacy in inhibiting glioma proliferation and invasion both in vitro and in vivo, making it significant in cancer research. Category: Active pharmaceutical ingredients. CAS No. 2387927-74-2. Product ID: API2387927742. Molecular formula: C53H57Cl2FIN7O. Mole weight: 1024.88. | |
| Irinotecan Hydrochloride | A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS. Category: Anti-tumor apis. Synonyms: Irinotecan Hcl. Topotecin. Campto. CAS No. 100286-90-6. Product ID: API100286906. Molecular formula: C33H39ClN4O6. Mole weight: 623.1. EINECS: 600-054-0. SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl. Appearance: Yellow solid. | |
| Iron protein succinylate | Iron protein succinylate is a mineral iron, a protein complex containing 5% trivalent iron bound to succinylated casein. Iron protein succinylate is used to treat iron deficiency anaemia (a deficiency of red blood cells due to too little iron in the body). It has a higher bioavailability than classical iron compounds. Category: Other apis. Synonyms: Protein succinate iron;iron protein. CAS No. 93615-44-2. Product ID: API93615442. | |
| iRucaparib-AP6 | iRucaparib-AP6, a highly efficient, specific, and non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. Category: Active pharmaceutical ingredients. CAS No. 2410557-00-3. Product ID: API2410557003. Molecular formula: C46H55FN6O11. Mole weight: 886.96. | |
| Islatravir | Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). Category: Active pharmaceutical ingredients. CAS No. 865363-93-5. Product ID: API865363935. Molecular formula: C12H12FN5O3. Mole weight: 293.25. | |
| Isoginkgetin | Isoginkgetin is a naturally occurring biflavonoid extracted mainly from Ginkgo biloba leaves. Isoginkgetin has been found to possess significant activity in various pharmacological studies. Applications: Isoginkgetin has been demonstrated to have therapeutic potential for the treatment of osteoarthritis and as a prophylactic against metabolic cardiomyopathy. the compound has shown potential for various types of cancer, such as myeloma, breast cancer, and cervical cancer. being a naturally sourced active molecule, isoginkgetin can be used as a nutraceutical, pharmaceutical, and cosmetic ingredient for the management of inflammation, anti-aging, and metabolic or degenerative disorders. Category: Natural extract. Synonyms: 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-methoxy-5-(4-oxo-5,7-dihydroxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one. CAS No. 548-19-6. Product ID: PIPE-0821. Molecular formula: C32H22O10. Mole weight: 566.51. InChIKey: HUOOMAOYXQFIDQ-UHFFFAOYSA-N. Appearance: White powder. | |
| Isomalt | Isomalt is incorporated into sugar-free products due to its tolerable aftertaste and sweet purity. The compound can be applied to a wide range of foods such as low-fat ice-cream. Applications: Food and nutraceutical industries. Category: Natural extract. Synonyms: Mixture Of 1-(4-Fluorophenyl-3S-[3-(4-Fluorophenyl-3S-Hydroxypropyl]-4S-(4-Hydroxyphenyl-AzetidiN-2-One And 1-(4-Fluorophenyl-3R-[3-(4-Fluorophenyl-3R-Hydroxypropyl]-4R-(4-Hydroxyphenyl-Azetidin;alpha-D-glucopyranosyl-1,6-D-sorbitolpolymerwithD-Mannitol;mixedwith1-o-alpha-d-glucopyranosyl-d-glucito;α-D-Glucopyranosyl-1,6-D-sorbitol;Isomaleone glycol;yimaiyatonyangsun;D-arabino-Hexitol,;ISOMALTITOL; PALATINITOL. CAS No. 64519-82-0. Product ID: PIPE-0228. Molecular formula: C12H24O11. Mole weight: 344.31. EINECS: 908-700-6. InChIKey: RWJWQKXVEITNKS-JSOWRAQNSA-N. Standard: In house. | |
| Isopropamide Iodide | Isopropamide iodide is a quaternary ammonium anticholinergic agent that was used to reduce gastric acid secretion and gastrointestinal motility. It contains iodine, providing weak radio - opacity for imaging purposes. Applications: Isopropamide was indicated as adjunctive therapy for peptic ulcer disease, gastritis, and irritable bowel syndrome to reduce hypermotility and hypersecretion. it was also used to control diarrhea. Category: Active pharmaceutical ingredients. Synonyms: Darbid; Dipramid; Dipramide; Piaccamide; Priamide; Priazimide. CAS No. 71-81-8. Product ID: API0231635. Molecular formula: C23H33IN2O. Mole weight: 480.4. EINECS: 200-766-8. InChIKey: BFSMWENDZZIWPW-UHFFFAOYSA-N. Appearance: White to off-white crystalline powder. | |
| Itopride Hydrochloride | Reversible AChE inhibitor. D2 receptor antagonist. Raises motilin and somatostatin levels. Lowers CCK levels. Shows gastroprokinetic effects in vivo. Orally active. Category: Other apis. Synonyms: ITOPRIDE HCl. Ganaton. Itopride (hydrochloride). CAS No. 122892-31-3. Product ID: API122892313. Molecular formula: C20H27ClN2O4. Mole weight: 394.9. EINECS: 602-905-1. SMILES: CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C=C2)OC)OC.Cl. Appearance: Crystalline solid. | |
| Ivosidenib | Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular differentiation and inhibit cellular proliferation in IDH1-expressing tumor cells. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 1448347-49-6. Product ID: API1448347496. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.96. Standard: GMP. | |
| Ixazomib | ixazomib is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated. Category: Active pharmaceutical ingredients. Synonyms: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid. Ixazomib Citrate (MLN9708). 4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid. CAS No. 1201902-80-8. Product ID: API1201902808. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.1. SMILES: B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl. Appearance: White to Off-White Solid. | |
| Janumet | Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. Category: Active pharmaceutical ingredients. CAS No. 1011232-08-8. Product ID: API1011232088. Molecular formula: C20H30ClF6N10O5P. Mole weight: 670.93. | |
| Kakadu Plum Extract | Kakadu Plum Extract is made from the fruit of Terminalia ferdinandiana, an Australian rainforest tree. As well as containing high amounts of polyphenols, it is also one of the highest known sources of Vitamin C (also known as L-ascorbic acid) naturally found in plants. Extracts made from the kakadu plum have traditionally been used as supplements in pharmaceutical and cosmeceutical formulations as a natural preservative, providing superior stability in comparison to synthetic antioxidants. Applications: Used topically in skin care products as a premium antioxidant and collagen stimulator. supplement ingredient in pharmaceutical grade products targeting immune system enhancement and other metabolic activities. applied in the food industry as a natural antioxidant to prolong the shelf life of oils/fats. also used as a protective ingredient in hair care products to help combat environmental build-up. Category: Natural extract. Product ID: PIPE-0305. Standard: In house. | |
| Ketanserin | Ketanserin (Ketanserinum) is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration, ketanserin binds to and inhibits the signaling mediated by 5-HTR2, which inhibits serotonin-dependent vasoconstriction and platelet activation. Category: Active pharmaceutical ingredients. CAS No. 74050-98-9. Product ID: API74050989. Molecular formula: C22H22FN3O3. Mole weight: 395.43. | |
| Ketanserinol | Ketanserinol is the metabolite of ketanserin. Ketanserin is a hypotensive drug with 5-HT2 receptor antagonism, used to reverse pulmonary hypertension caused by protamine. Category: Active pharmaceutical ingredients. CAS No. 76330-73-9. Product ID: API76330739. Molecular formula: C22H24FN3O3. Mole weight: 397.44. | |
| Ketanserin tartrate | Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist with antihypertensive activity, inhibits serotonin-induced vasoconstriction and platelet activation, and can be used in the study of systemic sclerosis. Category: Active pharmaceutical ingredients. CAS No. 83846-83-7. Product ID: API83846837. Molecular formula: C26H28FN3O9. Mole weight: 545.51. | |
| Ketone Ester | Ketone ester is exogenous ketone bodies that may promote ketosis in humans. Category: Natural extract. Synonyms: (3R)-3-Hydroxybutanoic acid (3R)-3-hydroxybutyl ester;BD-AcAc 2;[(3R)-3-hydroxybutyl] (3R)-3-hydroxybutanoate;R-BHB;Butanoic acid, 3-hydroxy-, (3R)-3-hydroxybutyl ester, (3R)-;(R)-(R)-3-hydroxybutyl 3-hydroxybutanoate;(R)-3-hydroxybutyl (R)-3-hydroxybutyrate. CAS No. 1208313-97-6. Product ID: PIPE-0218. Molecular formula: C8H16O4. Mole weight: 176.21. SMILES: C(OCC[C@H](O)C)(=O)C[C@H](O)C. InChIKey: AOWPVIWVMWUSBD-RNFRBKRXSA-N. Standard: In house. | |
| Ketoprofen Lysinate | Non-steroid anti-inflammatory. Category: Active pharmaceutical ingredients. CAS No. 57469-78-0. Product ID: API57469780. Molecular formula: C22H28N2O5. Mole weight: 400.47. | |
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