BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Vildagliptin Impurity 3 Trifluoroacetate | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Alternative Names: Vildagliptin Carboxy Acid Metabolite Trifluoroacetate. CAS No. 565453-41-0. Molecular formula: C17H26N2O4. C2HF3O2. Mole weight: 436.43. |  |
| Vildagliptin Impurity E hydrochloride | An impurity of Vildagliptin, an anti-hyperglycemic agent of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. Alternative Names: Vildagliptin Impurity E HCl; 2-(3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloride. Molecular formula: C17H25N3O2.HCl. Mole weight: 339.87. | |
| Vildagliptin Related Compound A | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Alternative Names: Vildagliptin Imp.A; 2-Pyrrolidinecarbonitrile, 1-[2-(tricyclo[3.3.1.13,7]dec-1-ylamino)acetyl]-, (2S)-; Vildagliptin Deshydroxy Impurity; (S)-1-(2-((3R,5R,7R)-adamantan-1-ylamino)acetyl)pyrrolidine-2-carbonitrile. CAS No. 741657-02-3. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
| Villosin | Villosin is a natural diterpenoid isolated from the herbs of Hedychium coronarium. For its potent cytotoxic activity with IC(50) of 0.40 microM, villosin may be used as a potential lead molecule for antitumor therapeutic development. Uses: Anti-tumor. Alternative Names: 8(17),11,13-Labdatrien-16,15-olide. Grades: >98%. CAS No. 160598-92-5. Molecular formula: C20H28O2. Mole weight: 300.4. | |
| Viltolarsen sodium | Viltolarsen sodium. | |
| Vinaginsenoside R3 | Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, sedative, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food. Vinaginsenoside R3 is the first naturally occurring glycoside of dammarenediol 2. Alternative Names: β-D-Glucopyranoside, (3β)-20-(β-D-glucopyranosyloxy)dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;(3β)-20-(β-D-Glucopyranosyloxy)dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside. Grades: > 98%. CAS No. 156012-92-9. Molecular formula: C48H82O17. Mole weight: 931.15. | |
| Vina-ginsenoside R4 | Vina-ginsenoside R4 is a triterpenoid vina-ginsenoside standard extracted from Panax ginseng. Panax ginseng is a familiar herbal medicine which has been used as a tonic, sedative, anti-fatigue, or anti-gastric ulcer drug, and also has antidiabetic and antitumor activities. More than 40 ginsenosides have been identified, isolated and characterised till now. Alternative Names: β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-6,12-dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-. Grades: > 98%. CAS No. 156009-80-2. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Vinaginsenoside R8 | Vinaginsenoside R8 has the side chain with a migrated double bond on introduction of OH at C-25. Most of the known saponins have been isolated from other Panax spp., though gypenoside XVII and hemsloside Ma3 were not previously isolated from Araliaceae but from Cucurbitaceous plants. Alternative Names: β-D-Glucopyranoside, (3β,12β,23E)-20-(β-D-glucopyranosyloxy)-12,25-dihydroxydammar-23-en-3-yl 2-O-β-D-glucopyranosyl-. Grades: > 98%. CAS No. 156042-22-7. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Vincetoxicoside B | Vincetoxicoside B is a natural compound isolated from Polygonum paleaceum Wall. It exhibits antifungal activity. Uses: Pharmacological experiment, content determination, identification, active filter. Alternative Names: 3,5-Dihydroxy-2-(3,4-dihydroxyphenyl)-7-(α-L-rhamnopyranosyloxy)-4H-1-benzopyran-4-one; 7-(α-L-Rhamnopyranosyloxy)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-1-benzopyran-4-one; 7-(α-L-Rhamnopyranosyloxy)-3,5-dihydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one; Quercetin 7-rhamnoside; Vincetoxicoside B; Quercetin-7- O-α-L-rhaMnoside. Grades: >98%. CAS No. 22007-72-3. Molecular formula: C21H20O11. Mole weight: 448.38. | |
| Viniferol D | Viniferol D isolated from the stem of Vitis vinifera. Alternative Names: (3S,4S,4aR,5R,9bR,10S)-4-(3,5-Dihydroxyphenyl)-3,5,10-tris(4-hydr oxyphenyl)-3,4,4a,5,9b,10-hexahydro-11-oxabenzo[5,6]cyclohepta[1, 2,3,4-jkl]-as-indacene-2,6,8-triol. Grades: 0.975. CAS No. 625096-18-6. Molecular formula: C42H32O9. Mole weight: 680.7. | |
| Vinorine | Vinorine is a natural alkaloid found in the root of Rauvolfia serpentina. Vinorine shows antiarrhythmic activity. Uses: Antiarrhythmic. Alternative Names: (17R,19E)-1,2,19,20-Tetradehydro-1-demethylajmalan-17-ol 17-acetate. Grades: >98%. CAS No. 34020-07-0. Molecular formula: C21H22N2O2. Mole weight: 334.42. | |
| Vinyl azlactone | Vinyl azlactone is a reactive heterocyclic monomer. Alternative Names: 4,4-Dimethyl-2-vinyloxazol-5(4H)-one; 4,4-Dimethyl-2-vinyl-2-oxazolin-5-one; 2-Vinyl-4,4-dimethylazlactone. Grades: 95%. CAS No. 29513-26-6. Molecular formula: C7H9NO2. Mole weight: 139.15. | |
| Vinyl isobutyrate | Vinyl isobutyrate, a versatile chemical compound, is widely utilized in the fine chemical and pharmaceutical industries. Acting as a fundamental substrate, it participates in the production of diverse drug classes, including potent antibiotics and anticancer agents, among others. Further, this compound finds extensive application in the creation of alluring fragrances and flavors due to its unique chemical attributes. Its multitude of practical uses and capabilities render it an essential component of the modern chemical industry. Alternative Names: Vinylisobutyrate; Isobutyric acid, vinyl ester. Grades: 95%. CAS No. 2424-98-8. Molecular formula: C6H10O2. Mole weight: 114.14. | |
| Vinylmethylsiloxane-dimethylsiloxane copolymer silanol terminated | Vinylmethylsiloxane-dimethylsiloxane copolymer silanol terminated. CAS No. 67923-19-7. | |
| Violanthin | Violanthin is a flavonoid showing antioxidant and antibacterial activities. Alternative Names: Violanthin; 40581-17-7; C10196; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]chromen-4-one5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy -6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-me thyl-oxan-2-yl]chromen-4-one. Grades: 0.98. CAS No. 40581-17-7. Molecular formula: C27H30O14. Mole weight: 578.5. | |
| Vipadenant | Vipadenant is an adenosine A2 receptor antagonists used as an immunosuppressant. Alternative Names: BG-14; CEB-4520; V2006; VER-11135; VER-A00-11; VER-A00049; VER-ADO-49; VR-2006. CAS No. 442908-10-3. Molecular formula: C16H15N7O. Mole weight: 321.34. | |
| Viscidulin I | Viscidulin I is isolated from the roots of Scutellaria viscidula Bge. Alternative Names: 4H-1-Benzopyran-4-one, 2-(2,6-dihydroxyphenyl)-3,5,7-trihydroxy-; 5,7,2',6'-Tetrahydroxyflavonol. Grades: 98%. CAS No. 92519-95-4. Molecular formula: C15H10O7. Mole weight: 302.2. | |
| Viscidulin III | Viscidulin III isolated from the roots of Scutellaria viscidula Bge. It was more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines. Alternative Names: ganhuangenin; 2-(3,6-dihydroxy-2-methoxyphenyl)-5,7-dihydroxy-8-methoxychromen-4-one. Grades: 0.98. CAS No. 92519-91-0. Molecular formula: C17H14O8. Mole weight: 346.3. | |
| Vitexdoin A | Vitexdoin A isolated from the herbs of Vitex negundo. Alternative Names: (3R,4S)-6,7-Dihydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-3,4-dihydro-2-naphthalenecarbaldehyde. Grades: >95%. CAS No. 1186021-77-1. Molecular formula: C19H18O6. Mole weight: 342.4. | |
| Vitexilactone | Vitexilactone isolated from the seeds of Vitex trifolia L. Uses: Antifungal; antibacterial. Alternative Names: 4-[2-[(1R,4aα)-Decahydro-4β-acetoxy-1α-hydroxy-2α,5,5,8aβ-tetramethylnaphthalen-1-yl]ethyl]furan-2(5H)-one;4-[2-[(4aα)-4β-Acetoxy-1-hydroxy-2α,5,5,8aβ-tetramethyldecalin-1β-yl]ethyl]-2(5H)-furanone; [(1R,3R,4R,4aS,8aS)-4-hydroxy-3,4a,8,8-tetramethyl-4-[2-. Grades: 0.97. CAS No. 61263-49-8. Molecular formula: C22H34O5. Mole weight: 378.5. | |
| Vitexin-4''-O-glucoside | Vitexin-4''-O-glucoside is a flavonoid isolated from Crataegus pinnatifida Bunge. Alternative Names: 4''-O-Glucosylvitexin; Vitexin 4''-O-glucoside. Grades: 98%. CAS No. 178468-00-3. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Vitexolide D | Vitexolide D is extracted from the herbs of Vitex vestita. It displays moderate antibacterial activity against a panel of 46 Gram-positive strains. It has cytotoxic activities against the human fetal lung fibroblast MRC5 cell line and HCT-116 cancer cell line. Alternative Names: 12-Hydroxy-8(17),13-labdadien-16,15-olide; 4-[(1S)-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-1-hydroxyethyl]-2H-furan-5-one. Grades: 98.5%. CAS No. 1788090-69-6. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| Voclosporine | Voclosporine is an orally available calcineurin inhibitor and potent immunosuppressant used in combination with mycophenolate mofetil and corticosteroids for the treatment of acute lupus nephritis. Uses: A new agent for the treatment of noninfectious uveitis. Alternative Names: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; ISATX 247; R 1524; trans-ISA 247; Voclosporin; Luveniq; Lupkynis; 1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)nona-6,8-dienoyl][(2S)-2-aminobutanoyl]-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]. Grades: 98%. CAS No. 515814-01-4. Molecular formula: C63H111N11O12. Mole weight: 1214.62. | |
| Vonoprazan-[d3] | Vonoprazan-[d3] is a labelled Vonoprazan, a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Alternative Names: Vonoprazan-d3. Molecular formula: C17H13D3FN3O2S. Mole weight: 348.4. | |
| Vonoprazan Impurity 19 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 881674-58-4. Molecular formula: C11H10FNO. Mole weight: 191.20. | |
| Vonoprazan Impurity 1 fumarate | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate. Molecular formula: C21H21N3O6S. Mole weight: 443.47. | |
| Vonoprazan Impurity 24 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: Vonoprazan N-Oxide Impurity. Grades: 95%. CAS No. 1883595-39-8. Molecular formula: C17H14FN3O3S. Mole weight: 359.37. | |
| Vonoprazan Impurity 28 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: 2-phenyl-4-formylpyrrole; 5-Phenylpyrrole-3-carbaldehyde. Grades: 95 %. CAS No. 56448-22-7. Molecular formula: C11H9NO. Mole weight: 171.19. | |
| Vonoprazan Impurity 29 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: 881676-90-0; 5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde5-phenyl-1-pyridin-3-ylsulfonylpyrrole-3-carbaldehyde; Vonoprazan Impurity 29; SCHEMBL1156702. Grades: 95%. CAS No. 881676-90-0. Molecular formula: C16H12N2O3S. Mole weight: 312.34. | |
| Vorapaxar | SCH-530348 is a novel antiplatelet agent undergoing development by Schering-Plough Corp for the treatment and prevention of atherothrombosis. It is currently undergoing Phase-III clinical trials for acute coronary syndrome (unstable angina/non-ST segment elevation myocardial infarction) and secondary prevention of cardiovascular events in high-risk patients. Uses: Platelet aggregation inhibitors. Alternative Names: N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-Fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic Acid Ethyl Ester Sulfate; Sch 530348. Grades: 0.98. CAS No. 618385-01-6. Molecular formula: C29H33FN2O4. Mole weight: 492.58. | |
| Voriconazole Impurity 8 | One of the impurities of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Alternative Names: (αR,βR)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol. CAS No. 239807-03-5. Molecular formula: C16H14F3N5O. Mole weight: 349.32. | |
| VPA-985 | VPA-985, an azepine compound, has been found to be a Vasopressin receptor antagonist that could be used in some cardiovascular disease therapy like hyponatraemia. Uses: Drug used in the treatment and prevention of cardiovascular diseases. Alternative Names: CRTX-080; CRTX080; CRTX 080; VPA-985; VPA985; VPA 985; WAY-VPA-985; Lixivaptan; N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)phenyl]-5-fluoro-2-methylbenzamide;Lixivaptan; VPA-985. Grades: 98%. CAS No. 168079-32-1. Molecular formula: C27H21ClFN3O2. Mole weight: 473.94. | |
| VPS34-IN1 | VPS34-IN1 is a potent and selective Vps34 inhibitor with potential anticancer activity. VPS34-IN1 inhibits Vps34 with 25 nM IC50 in vitro. Alternative Names: VPS34IN1; VPS34 IN1; VPS34-IN1. Grades: 98%. CAS No. 1383716-33-3. Molecular formula: C21H24ClN7O. Mole weight: 425.91. | |
| VT-1161 | VT-1161 is a 14-alpha demethylase inhibitor as a tetrazole antifungal agent originated by Viamet Pharmaceuticals. VT-1161 shows potent efficacy in treatment of dermatophytosis in a guinea pig model. Phase II clinical trials for the treatment of Onychomycosis and Vulvovaginal candidiasis is on-going. Uses: Onychomycosis; vulvovaginal candidiasis. Alternative Names: VT 1161; VT1161; Oteseconazole. Grades: 98%. CAS No. 1340593-59-0. Molecular formula: C23H16F7N5O2. Mole weight: 527.40. | |
| VU0152099 | VU0152099 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM. VU0152099 has no agonist activity but potentiated responses of M4 to acetylcholine. Alternative Names: VU 0152099; VU-0152099. Grades: 98%. CAS No. 612514-42-8. Molecular formula: C18H17N3O3S. Mole weight: 355.41. | |
| VU 0357017 hydrochloride | The hydrochloride salt form of VU0357017 which is a selective M1 agonist and has been found to be probably effective in the treatment of hippocampal-dependent cognitive function deficits. EC50=477 ± 172 nM. Alternative Names: VU0357017; VU-0357017; VU 0357017; CID 25010775; CID25010775; CID-25010775; 4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride. Grades: >98%. CAS No. 1135242-13-5. Molecular formula: C18H27N3O3.HCl. Mole weight: 369.89. | |
| VU0405601 | VU0405601. CAS No. 712325-30-9. | |
| VU-0483605 | VU-0483605, an isoindol derivative, has been found to be a mGluR1 positive allosteric modulator and probably be effective against schizophrenia. EC50: 356 and 390 nM for rat and human receptors, respectively. Alternative Names: CHEMBL3628116; VU0483605, VU-0483605, VU 048360; AOB6248; SYN5042; AOB 6248; SYN 5042; AOB-6248; SYN-5042; 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide. Grades: 98%. CAS No. 1623101-11-0. Molecular formula: C20H10Cl3N3O3. Mole weight: 446.67. | |
| VX-661 | VX-661 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used in combination with Ivacaftor in the treatment of cystic fibrosis. Alternative Names: 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide; VX 661; VX661; Tezacaftor. Grades: 98%. CAS No. 1152311-62-0. Molecular formula: C26H27F3N2O6. Mole weight: 520.50. | |
| Wallicoside | Wallicoside, a natural compound extracted from the leaves of Wallichia disticha, presents itself as a promising therapeutic entity for the treatment of neurodegenerative disorders, including Alzheimer's disease. Its anti-inflammatory and antioxidant attributes render it a valuable candidate in the development of novel drug compounds for the treatment and prevention of such debilitating diseases. Alternative Names: Wallicoside; AKOS040762548; 88797-59-5. Grades: 98.0%. CAS No. 88797-59-5. Molecular formula: C61H98O26. Mole weight: 1247.43. | |
| Warangalone | Warangalone is a natural flavonoid found in the herbs of Erythrina addisoniae. Warangalone has significant cytotoxicity against HL-60 cells. Warangalone also shows anti-inflammatory activity. Uses: Cytotoxicity anti-inflammatory. Alternative Names: Scandenone; 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 5-hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-10-(3-methyl-2-butenyl)-. Grades: >95%. CAS No. 4449-55-2. Molecular formula: C25H24O5. Mole weight: 404.5. | |
| WAY 127039-A-1 sodium salt | WAY 127039-A-1 sodium salt is a metabolite of Bromfenac, a nonsteroidal anti-inflammatory drug (NSAID). Alternative Names: 2-Amino-3-(4-bromobenzoyl)phenyloxoacetic acid. Grades: >95%. CAS No. 1391052-54-2. Molecular formula: C15H9BrNNaO4. Mole weight: 370.13. | |
| WAY-150138 | WAY 150138, belonging to a novel group of thiourea compounds, can cause the inhibition of the herpes simplex virus. Alternative Names: WAY 150138;273388-09-3;WAY-150138;Benzamide, N-(3-chloro-4-((((5-chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)amino)phenyl)-2-fluoro-;N-(3-chloro-4-(3-(5-chloro-2,4-dimethoxyphenyl)thioureido)phenyl)-2-fluorobenzamide;Benzamide, N-[3-chloro-4-[[[(5-chloro-2,4-dimethoxyphenyl)amino]thioxomethyl]amino]phenyl]-2-fluoro-;SCHEMBL6815633;DTXSID30181775;AKOS040754403;N-[3-chloro-4-[(5-chloro-2,4-dimethoxyphenyl)carbamothioylamino]phenyl]-2-fluorobenzamide;N-[3-chloro-4-[(5-chloro-2,4-dimethoxy-phenyl)carbamothioylamino]phenyl]-2-fluoro-benzamide. Grades: >98%. CAS No. 273388-09-3. Molecular formula: C22H18Cl2FN3O3S. Mole weight: 494.37. | |
| WAY-320461 | WAY-320461 is a FAK inhibitor. Alternative Names: WAY 320461; WAY320461. CAS No. 491839-65-7. Molecular formula: C15H10BrN3O2S. Mole weight: 376.2. | |
| WAY-323096 | WAY-323096 is a bioactive compound. Alternative Names: WAY 323096; WAY323096; 2-(4-(4-Chlorophenyl)-1-oxophthalazin-2(1H)-yl)-N-(4-fluorophenyl)acetamide. CAS No. 684234-60-4. Molecular formula: C22H15ClFN3O2. Mole weight: 407.8. | |
| WAY-641966 | WAY-641966 is an anti-prion agent. Alternative Names: WAY 641966; WAY641966. CAS No. 259870-32-1. Molecular formula: C20H16N4. Mole weight: 312.4. | |
| Wedelialactone A | Wedelialactone A is isolated from the herbs of Wedelia trilobata. Alternative Names: Wedelialactone A; 175862-40-5; [(3aR,4R,4aS,5R,8R,8aR,9S,9aR)-5,8-dihydroxy-5,8a-dimethyl-3-methylidene-4-(2-methylpropanoyloxy)-2-oxo-3a,4,4a,6,7,8,9,9a-octahydrobenzo[f][1]benzofuran-9-yl] (E)-2-methylbut-2-enoate; AKOS040762504. Grades: 97.0%. CAS No. 175862-40-5. Molecular formula: C24H34O8. Mole weight: 450.53. | |
| Wedelolactone | Wedelolactone isolated from the herbs of Eclipta prostrata. It could significantly inhibit the activation of LX-2 cells. Uses: Anti-cancer. Alternative Names: 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one. Grades: 98.5%. CAS No. 524-12-9. Molecular formula: C16H10O7. Mole weight: 314.3. | |
| WEHI-345 | WEHI-345, a pyrazolo-pyridine derivative, is a RIPK2 inhibitor and has been found to influence the production of inflammatory cytokine. IC50: 0.13 μM. Uses: Wehi-345 is a ripk2 inhibitor and has been found to influence the production of inflammatory cytokine. Alternative Names: WEHI-345; WEHI345; WEHI 345. SCHEMBL10098386; CS-5045; HY-18937; CS 5045; HY 18937; CS5045; HY18937. Grades: 98%. CAS No. 1354825-58-3. Molecular formula: C22H23N7O. Mole weight: 401.46. | |
| WHI-P180 | WHI-P180 moderately inhibited ABCG2 function, exhibiting weak phototoxicity. The elimination half-life of WHI-P180 in CD-1 mice (BALB/ c mice) following i.v., i.p., or p.o. administration was less than 10 min. Systemic clearance of WHI-P180 was 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic i.p. bolus doses of 25 mg/kg, inhibited IgE / antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis. Alternative Names: WHI-P180; WHI-P-180; WHI-P 180; 3-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol; Janex 3; WHI-P 180; WHIP180. CAS No. 211555-08-7. Molecular formula: C16H15N3O3. Mole weight: 297.31. | |
| WHI-P258 | WHI-P258 is a Janus kinase 3 (JAK3) inhibitor. Alternative Names: WHI-P258; WHI-P 258; WHI-P-258; WHIP 258; 6,7-Dimethoxy-N-phenylquinazolin-4-amine. CAS No. 21561-09-1. Molecular formula: C16H15N3O2. Mole weight: 281.315. | |
| Wighteone | Wighteone, also called Erythrinin B, is a natural flavonoid isolated from the herbs of Glycyrrhiza glabra, has a potent anti-proliferative effect on human leukemia HL-60 cancer cell lines, it can effectively inhibit the proliferation of HER2-positive cancer cell lines, which is considered to be the result of downregulating HSP90 receptor and downstream signaling. Wighteone also exhibits cytocidal activity against KB cells in vitro. Uses: Anti-yeast; anti-fungal. Alternative Names: 3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran- 4-one;4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone;4',5,7-Trihydroxy-6-prenyl-isofla vone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Eryth. Grades: >98%. CAS No. 51225-30-0. Molecular formula: C20H18O5. Mole weight: 338.4. | |
| Wilfortrine | Wilfortrine is a natural compound of the sesquiterpenoid class found in the roots of Tripterygium wilfordii Hook. f. Wilfortrine exhibits an inhibitory effect on liver cancer cell proliferation. Alternative Names: Evonimine, 8-(acetyloxy)-O(sup 2)-deacetyl-8-deoxo-O(sup 2)-(3-furanylcarbonyl)-26-hydroxy-, (8-alpha)-. Grades: >98%. CAS No. 37239-48-8. Molecular formula: C41H47NO20. Mole weight: 873.814. | |
| Withaperuvin C | Withaperuvin C is a steroid isolated from Physali alkekengi. Alternative Names: (17S,22R)-6beta,14,17,20,22-Pentahydroxy-1-oxo-5beta-ergosta-2,4,24-triene-26-oic acid delta-lactone. Grades: 96.5%. CAS No. 81644-34-0. Molecular formula: C28H38O7. Mole weight: 486.605. | |
| Wnt-C59 | Wnt-C59 is a potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay. It was shown to arrest stemness and suppress growth of nasopharyngeal carcinoma in mice via Wnt pathway inhibition. Alternative Names: 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide. Grades: >98%. CAS No. 1243243-89-1. Molecular formula: C25H21N3O. Mole weight: 379.45. | |
| Wnt Inhibitor IWP-2 | IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM. Uses: Differentiation. Alternative Names: IWP 2, IWP-2, IWP2. Grades: 0.98. CAS No. 686770-61-6. Molecular formula: C22H18N4O2S3. Mole weight: 466.592. | |
| Wogonin | Wogonin is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties. Uses: Antibacterial; antimicrobial; antioxidant; diuretic; anti-inflammatory; anti-tumor. Alternative Names: 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on; 5,7-dihydroxy-8-methoxyflavone. Grades: >98%. CAS No. 632-85-9. Molecular formula: C16H12O5. Mole weight: 284.26. | |
| WS3 | WS3 induces proliferation of the mouse β cell line R7T1 with EC50 of 0.074 μM. Alternative Names: WS3; WS-3; WS 3. Grades: >98%. CAS No. 1421227-52-2. Molecular formula: C28H30F3N7O3. Mole weight: 569.58. | |
| WST-1 | WST-1. CAS No. 1500849-52-8. Molecular formula: C19H11IN5NaO8S2. Mole weight: 651.35. | |
| WST-8 | WST-8. CAS No. 193149-74-5. | |
| WZ-4002 | WZ-4002 is an EGFR phosphorylation inhibitor with selectivity for EGFR T790M. It has a framework of pyrimidine compound which is different from other EGFR inhibitors. WZ-4002 exhibits anti-tumor activity. Uses: Protein kinase inhibitors. Alternative Names: WZ4002; N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide; WZ 4002. CAS No. 1213269-23-8. Molecular formula: C25H27ClN6O3. Mole weight: 494.98. | |
| WZB 117 | WZB 117 is a GLUT inhibitor (Ki(app) = 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively) that inhibits passive glucose transport in human erythrocytes and cancer cell lines. It decreases extracellular lactate and intracellular ATP levels. WZB 117 was shown to attenuate erythrocyte 3-O-metylglucose (3MG) uptake in vitro (Ki = 6 μM) and inhibits tumor growth in a nude mouse model. Alternative Names: WZB117; WZB-117; WZB 117; 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate). Grades: ≥98% by HPLC. CAS No. 1223397-11-2. Molecular formula: C20H13FO6. Mole weight: 368.31. | |
| Xanthohumol D | Xanthohumol D usually comes from the herbs of Humulus lupulus. Xanthohumol and Xanthohumol D were confirmed to be potent inducers of quinone reductase. Uses: Inducers. Alternative Names: 3'-(2-Hydroxy-3-methylbutyl-3-enyl)-4,2',4'-trihydroxy-6'-methoxychalcone. Grades: >98%. CAS No. 274675-25-1. Molecular formula: C21H22O6. Mole weight: 370.4. | |
| Xanthomicrol | Xanthomicrol is a flavonoid lipid isolated from Dracocephalum kotschyii leaf extract, and exhibits antineoplastic activity. Alternative Names: 4',5-dihydroxy-6,7,8-trimethoxyflavone. CAS No. 16545-23-6. Molecular formula: C18H16O7. Mole weight: 344.3. | |
| Xanthoxyletin | Xanthoxyletin is isolated from Zanthoxylum. Alternative Names: 5-Methoxy-8,8-dimethyl-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one; 5-methoxy-8,8-dimethyl-pyrano[3,2-g]chromen-2-one;5-methoxy-8,8-dimethylpyrano[3,2-g]chromen-2-one. Grades: 98%. CAS No. 84-99-1. Molecular formula: C15H14O4. Mole weight: 258.27. | |
| Xanthyletin | Xanthyletin is an inhibitor of symbiotic fungus (Leucoagaricus gongylophorus) of leaf-cutting ant (Atta sexdens rubropilosa) that can be isolated from Citrus sinensis. Alternative Names: Xanthyletine. Grades: 98.5%. CAS No. 553-19-5. Molecular formula: C14H12O3. Mole weight: 228.24. | |
| XAV939 | XAV 939 is a tankyrase (TNKS) inhibitor with IC50 values of 11 nM and 4 nM for tankyrase 1 and 2 respectively. XAV 939 antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. It also suppresses proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Uses: Differentiation. Alternative Names: XAV939; XAV 939; XAV-939. 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. Grades: 0.98. CAS No. 284028-89-3. Molecular formula: C14H11F3N2OS. Mole weight: 312.31. | |
| Ximelagatran | Ximelagatran, an ester prodrug of melagatran, with anticoagulant effect, is the first member of direct thrombin inhibitors that can be taken orally. Uses: An orally active direct thrombin inhibitor; prodrug of melagatran. antithrombotic. Alternative Names: H 376-95; H 376/95; H 37695; H-37695; H37695; N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine Ethyl Ester; Exanta; H 376/95. Grades: >98%. CAS No. 192939-46-1. Molecular formula: C24H35N5O5. Mole weight: 473.57. | |
| XL-647 | XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits EGFR, HER2, VEGFR and EphB4 kinase. Alternative Names: XL-647; XL 647; XL647; EXEL-7647; EXEL 7647; EXEL7647; KD-019; KD 019; KD019. Grades: >98%. CAS No. 781613-23-8. Molecular formula: C24H25Cl2FN4O2. Mole weight: 491.39. | |
| XL 765 | XL 765 is a PI3K inhibitor used for the treatment of cancers. It also suppresses DNA-PK and mTOR. Alternative Names: XL765-II; XL765 II; XL765II; XL 765-II; XL-765-II; SAR 245409; SAR245409; SAR-245409; N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide; N-(4-(N-(3-((3,5-Dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide. CAS No. 1349796-36-6. Molecular formula: C31H29N5O6S. Mole weight: 599.662. | |
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