BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| UDP-Glucose | UDP-Glucose. CAS No. 133-89-1. |  |
| UK-5099 | UK-5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC). It inhibits pyruvate-dependent oxygen consumption. Alternative Names: UK 5099; UK5099; 2-Cyano-3-(1-phenylindol-3-yl)acrylate; 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-acrylic acid. Grades: 95%. CAS No. 56396-35-1. Molecular formula: C18H12N2O2. Mole weight: 288.30. | |
| Ularitide TFA | Urodilatin is a hormone that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Alternative Names: Urodilatin human trifluoroacetate salt. Grades: 98%. Molecular formula: C145H234N52O44S3 (free base). Mole weight: 3505.93 (free base). | |
| Ulinastatin | Ulinastatin is an acid-resistant protease inhibitor derived from human urine, acting as a potent anti-inflammatory agent. It was shown to inhibit the activities of a variety of enzymes, including trypsin, chymotrypsin, thrombin, kallikrein, plasmin, elastase, cathepsin, lipase, hyaluronidase, factors IXa, Xa, XIa, and XlIa, and polymorphonuclear leukocyte elastase. Alternative Names: Urinastatin; 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-furanyl)-. Grades: 95%. CAS No. 80449-31-6. Molecular formula: C13H16O3. Mole weight: 220.26. | |
| Ulipristal | Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. Alternative Names: CDB-2914; CDB2914; CDB 2914; Ulipristal; VA-2914; VA 2914; VA2914; PGL-4001; PGL 4001; PGL4001. Grades: >98%. CAS No. 159811-51-5. Molecular formula: C28H35NO3. Mole weight: 433.58. | |
| Ulixertinib | Ulixertinib, also known as VRT752271, is an inhibitor of ERK protein kinase. Alternative Names: (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271; Ulixertinib. Grades: 98%. CAS No. 869886-67-9. Molecular formula: C21H22Cl2N4O2. Mole weight: 433.333. | |
| Umbralisib | Umbralisib is an orally bioavailable and selective PI3K delta inhibitor that targets delta isoform with nanomolar potency, which is approximately 1000-fold selective over alpha isoform, >30-50 fold over beta isoform and >15-50 fold over gamma isoforms. Umbralisib is developed for lymphoma therapy. Alternative Names: TGR-1202; TGR 1202; TGR1202; RP5264; 2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one. CAS No. 1532533-67-7. Molecular formula: C31H24F3N5O3. Mole weight: 571.5. | |
| Umeclidinium bromide | Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). Alternative Names: GSK-573719, GSK573719, GSK 573719, GSK-573719A, GSK573719A, GSK 573719A, Incruse Ellipta, Umeclidinium bromide. Grades: 0.99. CAS No. 869113-09-7. Molecular formula: C29H34BrNO2. Mole weight: 508.5. | |
| UNC-0638 | UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity. UNC0638 markedly reduced the clonogenicity of MCF7 cells, reduced the abundance of H3K9me2 marks at promoters of known G9a-regulated endogenous genes and disproportionately affected several genomic loci encoding microRNAs. Alternative Names: UNC0638, UNC-0638, UNC 0638. Grades: 0.98. CAS No. 1255580-76-7. Molecular formula: C30H47N5O2. Mole weight: 509.739. | |
| UNC1215 | UNC1215 is a potent, selective antagonist of L3MBTL3 with cellular activity. UNC1215 has an IC50 of 20 nM and > 100-fold selectivity over 13 HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. Alternative Names: UNC1215, UNC-1215, UNC 1215; (2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone). Grades: >98%. CAS No. 1415800-43-9. Molecular formula: C32H43N5O2. Mole weight: 529.729. | |
| UNC-1999 | UNC1999, the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. UNC1999 was highly selective for EZH2 and EZH1 over a broad range of epigenetic and non-epigenetic targets. UNC1999 was orally bioavailable in mice, making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies. UNC-1999 represents a useful tools for the biomedical community to investigate the role of EZH2 and EZH1 in health and disease. Alternative Names: UNC1999; UNC 1999; UNC-1999. Grades: 0.98. CAS No. 1431612-23-5. Molecular formula: C33H43N7O2. Mole weight: 569.754. | |
| UNC-2025 | UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that UNC-2025 has similar subnanomolar activity against Flt3, an additional important target in acute myelogenous leukemia (AML), with pharmacologically useful selectivity versus other kinases examined. Alternative Names: Cyclohexanol, 4-[2-(butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-; trans-4-[2-(Butylamino)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexanol; MRX 6313; UNC 2025; UNC2025. Grades: ≥95%. CAS No. 1429881-91-3. Molecular formula: C28H40N6O. Mole weight: 476.66. | |
| UNC-2025 hydrochloride | UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor. Alternative Names: UNC-2025 hydrochloride; UNC 2025 hydrochloride; UNC2025 hydrochloride; (1r,4r)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol hydrochloride. Grades: >98%. CAS No. 2070015-17-5. Molecular formula: C28H41ClN6O. Mole weight: 513.12. | |
| UNC2250 | UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. Treatment with UNC2250 also resulted in decreased colony-forming potential in rhabdoid and NSCLC tumor cells. The results provide a rationale for further investigation of UNC2250 for therapeutic application in patients with cancer. Alternative Names: UNC-2250; UNC 2250. Grades: 98%. CAS No. 1493694-70-4. Molecular formula: C24H36N6O2. Mole weight: 440.58. | |
| UNC 3230 | UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM), displaying selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. UNC 3230 decreases PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. UNC 3230 exhibits antinociceptive effects in mouse models of chronic pain. Alternative Names: UNC3230; UNC-3230; UNC 3230; 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide. Grades: ≥99% by HPLC. CAS No. 1031602-63-7. Molecular formula: C17H20N4O2S. Mole weight: 344.43. | |
| Uncargenin C | Uncargenin C isolated from the leaves of Turpinia arguta. Alternative Names: Uncargenin C; 152243-70-4; MCULE-9269495116; NCGC00385553-01. Grades: 0.95. CAS No. 152243-70-4. Molecular formula: C30H48O5. Mole weight: 488.7. | |
| Uncarine A | Uncarine A is an alkaloid isolated from the leaves of Uncaria hirsuta. Alternative Names: Isoformosanine; methyl (1R,4aS,5aS,6S,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate. Grades: 97.0%. CAS No. 6899-73-6. Molecular formula: C21H24N2O4. Mole weight: 368.433. | |
| Uncinatone | Uncinatone is a natural diterpenoid found in the roots of Clerodendrum bungei Steud. Uncinatone shows inhibition of lipopolysaccharide-induced nitric oxide production and inhibitory activity against complement system. Alternative Names: cis-1,8,9,11b-Tetrahydro-7,11-dihydroxy-3,4,9,11b-tetramethylphenanthro[3,2-b]furan-6(2H)-one. Grades: >98%. CAS No. 99624-92-7. Molecular formula: C20H22O4. Mole weight: 326.39. | |
| Uniconazole | Uniconazole is a plant growth hormone that inhibits cytochrome P450 707As, resulting in a suppression of gibberellin production. Uses: Fungicides, industrial. Alternative Names: 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (βE)-; (βE)-β-[(4-Chlorophenyl)methylene]-α-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (E)-(±)-; (E)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol; 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methylene]-α-(1,1-dimethylethyl)-, (E)-; M 13144; Majic; Majic S 3307D; Pentefenzol; Prunit; S 07; S 327D; S 3307; S 3307D; Sumagic; Sumiseven; XE 1019; XE 1019D. Grades: 95%. CAS No. 83657-22-1. Molecular formula: C15H18ClN3O. Mole weight: 291.77. | |
| Uprosertib | Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine / threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Alternative Names: GSK-2141795; GSK2141795; GSK 2141795; GSK795; GSK-795; GSK 795. Uprosertib. CAS No. 1047634-65-0. Molecular formula: C18H16Cl2F2N4O2. Mole weight: 429.25. | |
| Uracil-m7GpppAmpG ammonium | Uracil-m7GpppAmpG ammonium is a cap analog that can be used for mRNA synthesis. Alternative Names: Uracil-m7GpppAmpG 100mM ammonium. Grades: 98%. Molecular formula: C31H42N12O25P4.xNH3. | |
| Urea,N-(4-ethoxyphenyl)- | N-(4-ethoxyphenyl)-Urea is an artificial sweetener about 250 times sweeter than sucrose, which is prohibited by FDA from use in human food for its carcinogenic property. Uses: Artificial sweetener. Alternative Names: Dulcin; 1-(4-Ethoxyphenyl)urea; N-(4-Ethoxyphenyl)urea; (4-ethoxyphenyl)urea; P-Ethoxyphenylurea. CAS No. 150-69-6. Molecular formula: C9H12N2O2. Mole weight: 180.23. | |
| Ursocholic acid | Ursocholic acid plays a role as a human urinary metabolite and a 7alpha-hydroxysteroid dehydrogenase inhibitor. Uses: Ursodeoxycholic acid (u850000) impurity. Alternative Names: 7-Epicholic acid; 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanic acid; 3a,7b,12a-Trihydroxycholanate; (3α,5β,7β,12α)-3,7,12-Trihydroxycholan-24-oic Acid; Ursodeoxycholic Acid EP Impurity D. Grades: 95%. CAS No. 2955-27-3. Molecular formula: C24H40O5. Mole weight: 408.57. | |
| Usaramine | Usaramine is a pyrrolizidine alkaloid found in the seeds of Crolatalaria pallida. Uses: Antiseptic. Alternative Names: NISTC15503874; (15E)-12,18-Dihydroxysenecionan-11,16-dione; Mucronatine; (15E)-Retrorsine; trans-Retrorsine; Usaramin. Grades: >98%. CAS No. 15503-87-4. Molecular formula: C18H25NO6. Mole weight: 351.4. | |
| Vaccarin | Vaccarin is a major flavonoid glycoside in Vaccariae semen, and is expected to be useful in the treatment of vascular diseases. Uses: Anti-early pregnancy. Alternative Names: 6-(2-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one. Grades: >98%. CAS No. 53452-16-7. Molecular formula: C32H38O19. Mole weight: 726.64. | |
| Valaciclovir EP Impurity C | An impurity of Valacyclovir, an antiviral drug used for the treatment of herpes virus infections. Alternative Names: L-Valine, N-methyl-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester; (S)-2-((2-Imino-6-oxo-2,3-dihydro-1H-purin-9(6H)-yl)methoxy)ethyl 3-methyl-2-(methylamino)butanoate; Acyclovir N-Methyl-L-valinate; 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl N-methyl-L-valinate; N-Methyl Valacyclovir. Grades: >95%. CAS No. 1346747-65-6. Molecular formula: C14H22N6O4. Mole weight: 338.36. | |
| Valacyclovir Related Compound D | An impurity of Valacyclovir, an antiviral drug used for the treatment of herpes virus infections. Alternative Names: Valaciclovir USP RC D; N-Ethyl Valacyclovir ; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl-N-ethyl-L-valinate. Grades: > 95%. CAS No. 1346747-69-0. Molecular formula: C15H15N5O4. Mole weight: 352.39. | |
| Val-cit-PAB-OH | Val-cit-PAB-OH is a protease cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-omithinamide; Val-cit-PAB; (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide. Grades: 95%. CAS No. 159857-79-1. Molecular formula: C18H29N5O4. Mole weight: 379.46. | |
| Valdecoxib Impurity B | Valdecoxib Impurity B is a dimeric impurity of Valdecoxib. Alternative Names: Valdecoxib Dimer; N-[4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl]-4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide. CAS No. 1373038-60-8. Molecular formula: C32H25N3O6S2. Mole weight: 611.7. | |
| Valdecoxib Impurity E | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Alternative Names: Valdecoxib IMpurity-E; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzenesulfonyl chloride; 3-[4-(4-chlorosulfonylphenyl)-5-methyl-1,2-oxazol-3-yl]benzenesulfonyl chloride; 3-(4-(4-(Chlorosulfonyl)phenyl)-5-methylisoxazol-3-yl)benzene-1-sulfonyl chloride; YEC03863; 3-[4-[4-(Chlorosulfonyl)phenyl]-5-methyl-3-isoxazolyl]benzenesulfonyl chloride; 1-?Tert-?butyl 4-?ethyl 1H-?pyrazole-?1,?4-?dicarboxylate. CAS No. 1373038-63-1. Molecular formula: C16H11Cl2NO5S2. Mole weight: 432.3. | |
| Valdecoxib Impurity I | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Alternative Names: 3-(5-methyl-4-(4-sulfamoylphenyl)isoxazol-3-yl)benzenesulfonamide; AKOS030530317; ZINC200584589; BC600176; 3-(3-Aminosulfonylphenyl)-4-(4-aminosulfonylphenyl)-5-methylisoxazole. CAS No. 1373038-59-5. Molecular formula: C16H15N3O5S2. Mole weight: 393.44. | |
| Valganciclovir hydrochloride | Valganciclovir hydrochloride. CAS No. 175865-59-5. | |
| Val-glu-pro-ile-pro-tyr | Val-glu-pro-ile-pro-tyr. Alternative Names: Valyl-glutamyl-prolyl-isoleucyl-prolyl-tyrosine; Vepipy; H-Val-Glu-Pro-Ile-Pro-Tyr-OH. CAS No. 94773-24-7. Molecular formula: C35H52N6O10. Mole weight: 716.82. | |
| Valrubicin | Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder. Uses: Antineoplastic. Alternative Names: Pentanoic Acid 2-[(2S,4S)-1,2,3,4,6,11-Hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl Ester; Antibiotic AD 32; N-Trifluoroacetyladriamycin 14-Valerate; NSC 246131; Valstar; Valtaxin; 2-Oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydro-2-tetracenyl]ethyl valerate. Grades: >98%. CAS No. 56124-62-0. Molecular formula: C34H36F3NO13. Mole weight: 723.64. | |
| Valsartan Desvaleryl Impurity | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Alternative Names: Des(oxopentyl) Valsartan; N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine. CAS No. 676129-92-3. Molecular formula: C19H21N5O2. Mole weight: 351.41. | |
| Valsartan Ethyl Ester | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Alternative Names: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Ethyl Ester. CAS No. 1111177-30-0. Molecular formula: C26H33N5O3. Mole weight: 463.58. | |
| Vamorolone | Vamorolone. CAS No. 13209-41-1. | |
| Vancomycin-[d12] trifluoroacetate salt | Vancomycin-[d12] trifluoroacetate salt is the labelled analogue of Vancomycin trifluoroacetate salt. Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. Alternative Names: Vancomycin-[d12] TFA salt; Vancomycin trifluoroacetate salt-d12; d12-Vancomycin trifluoroacetate salt. Molecular formula: C66H63D12Cl2N9O24.C2F3O2H. Mole weight: 1575.35. | |
| Vandetanib | Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM. Uses: Antineoplastic. Alternative Names: ZD6474; ZD 6474; ZD-6474; 4-Quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; AZD 6474; AZD-6474; AZD6474; Caprelsa; CH 331; N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(N-methylpiperidin-4-ylmethoxy)quinazolin-4-amine; Zactima. Grades: >98%. CAS No. 443913-73-3. Molecular formula: C22H24BrFN4O2. Mole weight: 475.35. | |
| Vandrikidine | Vandrikidine is a natural alkaloid isolated from the herb of Melodinus khasianus. Alternative Names: Methyl (5α,12β,19α,20R)-20-hydroxy-16-methoxy-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate. Grades: >98%. CAS No. 50656-92-3. Molecular formula: C22H26N2O4. Mole weight: 382.5. | |
| Vanilloloside | Vanilloloside. CAS No. 74950-96-2. | |
| Varenicline-[d4] | Varenicline-[d4] is the labelled analogue of Varenicline, which is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Alternative Names: Varenicline-d4; Varenicline D4; 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine-d4 Hydrochloride. CAS No. 2183239-01-0. Molecular formula: C13H9D4N3. Mole weight: 215.29. | |
| (-)-Variabilin | (-)-Variabilin is a phenolic compound found in the herbs of Angelica sinensis. (-)-Variabilin exhibits activity of antimicrobial and is an important chemotaxonomic marker for the family Irciniidae. Uses: Antimicrobial. Alternative Names: (-)-Homopisatin; 6a-Hydroxy-3,9-dimethoxypterocarpan; (6aS,11aS)-3,9-Dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol. Grades: >97%. CAS No. 370102-93-5. Molecular formula: C17H16O5. Mole weight: 300.3. | |
| Vasicil | Vasicinol, which usually comes from the leaves of Adhatoda vasica Nees, shows a high sucrase inhibitory activity with IC50 value of 250 μM. It could be used to treat metabolic disorders. It also can be used as a transient hypotensive agent, cardiac depressant and histamine antagonist. Vasicinol shows mild anticholinesterase activity. Uses: Anticholinesterase. Alternative Names: Vasicil; (+)-6-Hydroxypeganine; 6-Hydroxypeganine; 6-Hydroxyvasicine. Grades: >98%. CAS No. 5081-51-6. Molecular formula: C11H12N2O2. Mole weight: 204.2. | |
| Vasicilone | Vasicinolone usually comes from the leaves of Adhatoda vasica. Uses: Anti-inflammatory / antimicrobial. Alternative Names: Vasicilone; (S)-2,3-Dihydro-3,7-dihydroxypyrrolo[2,1-b]quinazolin-9(1H)-one; (S)-3,7-Dihydroxy-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one. Grades: >98%. CAS No. 84847-50-7. Molecular formula: C11H10N2O3. Mole weight: 218.2. | |
| Vatalanib | Vatalanib, also called as PTK 787 or CGP 797870, is a small molecule that interacts reversibly and competitively at the ATP-binding site of the receptor tyrosine kinase domain to inhibit autophosphorylation. It targets all known VEGFR tyrosine kinases. Alternative Names: N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine; PTK787; PTK 787; PTK-787; ZK 222584; ZK222584; ZK-222584; CGP 79787; CGP-797870; ZK-232934; CGP79787D; ZK 222584; CGP-7978. Grades: >98%. CAS No. 212141-54-3. Molecular formula: C20H15ClN4. Mole weight: 346.81. | |
| Vat-Cit-PAB-MMAD | Vat-Cit-PAB-MMAD is a protective group conjugated MMAD, MMAD is a toxin payload in antibody drug conjugate. Alternative Names: Vat-Cit-PAB-Monomethyl Dolastatin 10. CAS No. 1415329-13-3. Molecular formula: C60H93N11O11S. Mole weight: 1176.51. | |
| Vegita | Vegita is a metabolite of maneb, a fungicide. Alternative Names: Hortocritt; Ethylenethiuramsulfide; Ethylenethiurammonosulfide; ETM(heterocycle); ETEM. Grades: 95%. CAS No. 33813-20-6. Molecular formula: C4H4N2S3. Mole weight: 176.28. | |
| Veliparib | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (>4 fold at 24 h). Uses: For research used only. Alternative Names: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib. Grades: 0.99. CAS No. 912444-00-9. Molecular formula: C13H16N4O. Mole weight: 244.298. | |
| Vellosimine | Vellosimine is a natural alkaloid found in the herbs of Rauvolfia verticillata. Alternative Names: 4-ethyl-4-phenyl-piperidine-2,6-dione; 2,6-Piperidinedione,4-ethyl-4-phenyl. Grades: >95%. CAS No. 6874-98-2. Molecular formula: C19H20N2O. Mole weight: 292.4. | |
| Vemurafenib | Vemurafenib is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity than wild-type B-Raf. Alternative Names: PLX4032; PLX 4032; PLX-4032; RG7204 ; RG7204 ; RG 7204 ; RO5185426; RO 5185426 RO5185426 Vemurafenib; Brand name: Zelboraf. Grades: >98%. CAS No. 918504-65-1. Molecular formula: C23H18ClF2N3O3S. Mole weight: 489.92. | |
| Venlafaxine-[d10] Hydrochloride | One of the isotopic labelled form of Venlafaxine HCl, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Alternative Names: D,L-Venlafaxine-d10 Hydrochloride; 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride-d10. CAS No. 1216539-56-8. Molecular formula: C17H18D10ClNO2. Mole weight: 323.92. | |
| Venlafaxine EP Impurity A hydrochloride | Venlafaxine EP Impurity A hydrochloride is an impurity of Venlafaxine, which is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Alternative Names: Descyclohexanol Venlafaxine HCl; 4-Methoxy-N,N-dimethylbenzeneethanamine hydrochloride; p-Methoxy-N,N-dimethyl-phenethylamine hydrochloride; N,N-Dimethyl-2-(p-anisyl)ethylamine hydrochloride; N,N-Dimethyl-4-methoxyphenethylamine hydrochloride; Benzeneethanamine, 4-methoxy-N,N-dimethyl-, hydrochloride (1:1); Venlafaxine Hydrochloride EP Impurity A hydrochloride; Phenethylamine, p-methoxy-N,N-dimethyl-, hydrochloride; 4-Methoxy-N,N-dimethylphenethylamine hydrochloride; [2-(4-Methoxyphenyl)ethyl]dimethylamine hydrochloride; p-Methoxy-N,N-dimethylphenethylamine hydrochloride; 2-(4-Methoxyphenyl)-N,N-dimethylethylamine hydrochloride. Grades: ≥95%. CAS No. 50822-98-5. Molecular formula: C11H17NO.HCl. Mole weight: 215.72. | |
| VER-155008 | VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Alternative Names: 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine; C07; VER 155008; VER155008; 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-Adenosine; 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile. Grades: ≥95%. CAS No. 1134156-31-2. Molecular formula: C25H23Cl2N7O4. Mole weight: 556.40. | |
| (±)-Verapamil-[d3] HCl | One of the isotopic labelled form of (±)-Verapamil, which is a calcium channel blocker and could be used as antiarrhythmic and antihypertensive agent. Alternative Names: 5-((3,4-Dimethoxyphenethyl)(methyl-d3)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile monohydrochloride. Grades: 95% by HPLC; 98% atom D. Molecular formula: C27H36D3ClN2O4. Mole weight: 494.09. | |
| Verapamil Impurity J HCl | Verapamil Impurity J HCl is a metabolite of Verapamil. Verapamil is a medication used for the treatment of high blood pressure, chest pain from not enough blood flow to the heart, and supraventricular tachycardia. Alternative Names: Nor Verapamil Hydrochloride; α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile. CAS No. 67812-42-4. Molecular formula: C26H36N2O4. HCl. Mole weight: 477.05. | |
| Veratramine | Veratramine is useful as a signal transduction inhibitor for treating tumors. Alternative Names: Veratramine; NSC 17821; NSC17821; NSC-17821; NSC 23880; NSC-23880; NSC23880. Grades: >98%. CAS No. 60-70-8. Molecular formula: C27H39NO2. Mole weight: 409.6. | |
| Veratric Acid-[d6] | Veratric Acid-[d6] is the deuterated form of Veratric Acid which is a natural phenol found in the fruits of Phyllanthus emblica L. Alternative Names: 3,4-Dimethoxybenzoic Acid-d6; Dimethylprotocatechuic Acid-d6; NSC 7721-d6. Grades: ≥90%. CAS No. 1162658-12-9. Molecular formula: C9H4D6O4. Mole weight: 188.21. | |
| Verucerfont | Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively. Verucerfont supresses the CRH-1 receptor to decrease ACTH release following chronic stress. Alternative Names: GSK561679; GSK 561679; GSK-561679; GSK561679A; NBI-77860; NBI 77860; NBI77860; 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 885220-61-1. Molecular formula: C22H26N6O2. Mole weight: 406.49. | |
| (±)-Vesamicol hydrochloride | (±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Alternative Names: AH5183 hydrochloride; AH 5183 hydrochloride; (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride; 2-(4-Phenylpiperidino)cyclohexanol hydrochloride; Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride. Grades: ≥99% by HPLC. CAS No. 120447-62-3. Molecular formula: C17H25NO.HCl. Mole weight: 295.85. | |
| VH 032-linker 6 | VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Alternative Names: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75. | |
| VH-298 | VH-298 is a high-affinity inhibitor of E3 ubiquitin ligase VHL (Kd value of 80-90 nM) that could block VHL and HIF-α interactions. VH-298 can be used in PROTAC technology. Uses: Enzyme inhibitors. Alternative Names: (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; EX-A1505; VH 298; VH298; VH-298. Grades: ≥98% by HPLC. CAS No. 2097381-85-4. Molecular formula: C27H33N5O4S. Mole weight: 523.65. | |
| Vibsanin C | Vibsanin C is a natural diterpenoid found in the herbs of Viburnum cylindricum. Alternative Names: 3-Methyl-2-butenoic acid [2-[5-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-6-oxo-7-(2-oxopropyl)-4-cyclohepten-1-yl]vinyl] ester. Grades: >95%. CAS No. 74690-89-4. Molecular formula: C25H36O5. Mole weight: 416.56. | |
| Viburnumoside | Viburnumoside is a hispanane-type diterpenoid glucoside and belongs to the scarce group of natural diterpenoid. Grades: 98.0%. CAS No. 2222365-74-2. Molecular formula: C26H38O8. Mole weight: 478.58. | |
| Vicenin-3 | Vicenin-3 is extracted from the herbs of Chrysanthemi indici L. It has radioprotective effects. It can protect against foetal irradiation-induced instability and genomic damage, thus reduces the delayed tumorigenesis and chromosomal abnormalities in adult. Alternative Names: 6-beta-D-Glucopyranosyl-8-beta-D-xylopyranosylapigenin; 6-C-Glucosyl-8-C-xylosylapigenin; Vicenin III; 6-C-beta-D-Glucopyranosyl-8-C-beta-D-xylopyranosylapigenin; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one. Grades: 98.0%. CAS No. 59914-91-9. Molecular formula: C26H28O14. Mole weight: 564.50. | |
| Vicenin I | Vicenin I is a natural compound which can be isolated from Vitex negundo L., Linum grandiflorum, etc. Alternative Names: Vicenin-1. CAS No. 35927-38-9. Molecular formula: C26H28O14. Mole weight: 564.49. | |
| Vidofludimus | Vidofludimus is an orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 134 nM for human DHODH. Phase 2. Alternative Names: SC12267, SC 12267; SC-12267; 4SC-101; 4SC 101; 4SC101. Grades: 98%. CAS No. 717824-30-1. Molecular formula: C20H18FNO4. Mole weight: 355.36. | |
| Vigabatrin EP Impurity E | Vigabatrin EP Impurity E is a derivative of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Alternative Names: 2-(2-Aminobut-3-enyl)malonic Acid. CAS No. 1378466-25-1. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
| Vigabatrin Hydrochloride | A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic. Alternative Names: γ-Vinyl-GABA hydrochloride; Sabril hydrochloride. Grades: >98%. CAS No. 1391054-02-6. Molecular formula: C6H12ClNO2. Mole weight: 165.62. | |
| Vildagliptin Carboxylic Acid Metabolite | Vildagliptin Carboxylic Acid Metabolite is a major metabolite of vildagliptin. Alternative Names: N-(3-Hydroxytricyclo[3.3.1.1~3,7~]decan-1-yl)glycyl-L-proline. CAS No. 565453-40-9. Molecular formula: C17H26N2O4. Mole weight: 322.405. | |
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