BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ribonucleic acid, transfer from Escherichia coli | tRNA plays an important role in protein biosynthesis. Its mutual recognition with aminoacyl-tRNA synthetase (aaRS) ensures the accuracy of translation. Transfer RNA extracted from Escherichia coli can be used as a starting material to purify specific aminoacyl-tRNA species by methods such as liquid column chromatography or high performance liquid chromatography (HPLC). Alternative Names: Transfer RNA; tRNA. Grades: >90% by agarose gel electrophoresis. CAS No. 9014-25-9. |  |
| R-Ibuprofen | R-Ibuprofen is an inhibitor of Cox-1 and Cox-2 used as a nonsteroidal anti-inflammatory drug. Alternative Names: l-Ibuprofen; Levibuprofen; (R)-(-)-Ibuprofen; (R)-Ibuprofen. Grades: > 95%. CAS No. 51146-57-7. Molecular formula: C13H18O2. Mole weight: 206.28. | |
| Rice bran wax | Rice bran wax. Alternative Names: Waxes and Waxy substances, rice bran; ORYZA SATIVA (RICE) BRAN WAX; RICE(ORYZASATIVA)WAX; RICEWAX. CAS No. 8016-60-2. Molecular formula: C50H44N8O2. Mole weight: 788.90. | |
| Ricin A chain from Ricinus communis (castor bean) | Ricin A chain from Ricinus communis (castor bean). CAS No. 96638-28-7. | |
| Ricinine | Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Alternative Names: Ritsinin; 1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile; 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile. Grades: 98 % (TLC). CAS No. 524-40-3. Molecular formula: C8H8N2O2. Mole weight: 164.16. | |
| Ricinoleic acid | Ricinoleic acid is found in castor-oil plants. Alternative Names: 9-Octadecenoic acid, 12-hydroxy-, (9Z,12R)-; (9Z,12R)-12-Hydroxy-9-octadecenoic acid; 9-Octadecenoic acid, 12-hydroxy-, [R-(Z)]-; (9Z,12R)-12-Hydroxyoctadec-9-enoic acid; (R)-12-Hydroxyoleic acid; (R)-Ricinoleic acid; 12-D-Hydroxy-9-cis-octadecenoic acid; 12-Hydroxy-cis-9-octadecenoic acid; 12-Hydroxyoctadeca-9-enoic acid; 9-Nonadecenoic acid, 12-hydroxy-, (9Z,12R)-; Cenwax C; CS 80; Edenor Ri 90; H 1657; Nouracid CS 80; Nouracid CZ 80; NSC 281242; Ricinic acid; Ricinolic acid. Grades: ≥95%. CAS No. 141-22-0. Molecular formula: C18H34O3. Mole weight: 298.46. | |
| Ricinoleyl alcohol | Ricinoleyl alcohol. Alternative Names: DELTA 9-12 OH RICINOLEYL ALCOHOL; RICINOLEYL ALCOHOL; octadec-9-ene-1,12-diol; (9Z,12R)-9-Octadecene-1,12-diol; [Z,R,(+)]-9-Octadecene-1,12-diol; [Z,S,(-)]-9-Octadecene-1,12-diol; Einecs 208-737-1. Grades: technical. CAS No. 540-11-4. Molecular formula: C18H36O2. Mole weight: 284.48. | |
| Rifabutin | Rifabutin inhibits bacterial RNA polymerase. Alternative Names: Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-; (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-16-(Acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione; Rifamycin XIV, 1',4-didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxo-; Ansamycin; Antibiotic LM 427; LM 427; Mycobutin; R 3530; Rifabutine. Grades: >98%. CAS No. 72559-06-9. Molecular formula: C46H62N4O11. Mole weight: 847.01. | |
| Rifabutin EP Impurity B (3-Amino Rifamycin S) | A derivative of Rifabutin.Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. Alternative Names: 3-Amino-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin. Grades: > 95%. CAS No. 51756-80-0. Molecular formula: C37H46N2O12. Mole weight: 710.79. | |
| Rifabutin EP Impurity D | A derivative of Rifabutin.Rifabutin is an antibiotic used to treat tuberculosis and prevent and treat Mycobacterium avium complex. Alternative Names: 3-Amino-1,4-dideoxy-1,4-dihydro-4-imino-1-oxorifamycin; 3-Amino-4-iminorifamycin S; 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, Rifamycin Deriv.; 3-Amino-4-deoxo-4-iminorifamycin S; 3-Amino-4-deoxy-4-iminorifamycin S; 3-Amino-1,4-dideoxy-1,4-dihydro-4-imino-1-oxorifamycin. Grades: 90%. CAS No. 62041-01-4. Molecular formula: C37H47N3O11. Mole weight: 709.8. | |
| Rifampicin N-Oxide | A metabolite of Rifampicin. Rifampicin is an antibiotic used to treat several types of bacterial infections. This includes tuberculosis, leprosy, and Legionnaire's. Alternative Names: 3-[[(4-Methyl-4-oxido-1-piperazinyl)imino]methyl]rifamycin; 3-[[(4-methyl-1-piperazinyl)imino]methyl]rifamycin N-4'-Oxide. Grades: > 95%. CAS No. 125833-03-6. Molecular formula: C43H58N4O13. Mole weight: 838.96. | |
| Rifampicin Quinone | A metabolite of Rifampicin. Rifampicin is an antibiotic used to treat several types of bacterial infections. This includes tuberculosis, leprosy, and Legionnaire's. Alternative Names: 1,4-Dideoxy-1,4-dihydro-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]-1,4-dioxo-Rifamycin; Rifampin Quinone; 5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone 21-Acetate; NSC 145633; Rifaldazinequinone. Grades: > 95%. CAS No. 13983-13-6. Molecular formula: C43H56N4O12. Mole weight: 820.95. | |
| Rifampicin sodium salt | Rifampicin sodium salt. Alternative Names: Rifadine(TN);38776-75-9;D08479. Grades: 95%. CAS No. 38776-75-9. Molecular formula: C43H58N4NaO12. Mole weight: 845.929989. | |
| Rifamycin SV sodium salt | Rifamycin SV sodium salt. Alternative Names: Nsc133100. Grades: 95%. CAS No. 15105-92-7. Molecular formula: C37H47NO12. | |
| Rifaximin | Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. It is used to prevent and treat milk cow mastitis in the dry period caused by sensitive bacteria such as Staphylococcus aureus, Streptococcus and E. coli. Alternative Names: 4-Deoxy-4'-methylpyridol[1',2'-1,2]imidazo[5,4-c]rifamycin SV; Rifamycin L 105; Rifaxidin; L-105; Fatroximin; Normix; Rifacol; Xifaxan. Grades: >98%. CAS No. 80621-81-4. Molecular formula: C43H51N3O11. Mole weight: 785.88. | |
| Rifaximin EP Impurity A | Rifaximin EP Impurity A is an impurity of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Alternative Names: 4-Methyl-2-pyridinamine; 2-Amino-4-picoline; Aminopicoline; Ascensil; NSC 1490; NSC 176165; NSC 6972. CAS No. 695-34-1. Molecular formula: C6H8N2. Mole weight: 108.14. | |
| Rifaximin EP Impurity D | Rifaximin EP Impurity D is an impurity of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Alternative Names: Rifaximin Y. Grades: >95%. Molecular formula: C43H49N3O12. Mole weight: 799.86. | |
| Rifaximin EP Impurity G | Rifaximin EP Impurity G is an intermediate of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Alternative Names: Dehydro Rifaximin; 6-o,14-Didehydrorifaximin; [2S-(2R*,16Z,18E,20R*,21R*,22S*,23S*,24S*,25R*,26S*,27R*,28E)]-25-(Acetyloxy)-5,21,23-trihydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-6H-27-(epoxypentadeca[1,11,13]trienonitrilo)benzofuro[4,5-e]pyrido[1,2-a]benzimidazole-1,6,15(2H)-trione. Grades: 90%. CAS No. 80621-76-7. Molecular formula: C43H49N3O11. Mole weight: 783.86. | |
| Rifaximin EP Impurity H | Rifaximin EP Impurity H is an intermediate of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. Alternative Names: 16-Desmethyl-16-(hydroxymethyl)rifaximin; (2S,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-25-(Acetyloxy)-5,6,21,23-tetrahydroxy-16-(hydroxymethyl)-27-methoxy-2,4,11,20,22,24,26-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-E)pyrido(1,2-a)benzimidazole-1,15(2H)-dione. Grades: 90%. CAS No. 1210022-90-4. Molecular formula: C43H51N3O12. Mole weight: 801.88. | |
| Rilapladib | Rilapladib is the third genomics-derived small molecule drug as a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor which is an enzyme associated with the formation of atherosclerotic plaques. Uses: 1-alkyl-2-acetylglycerophosphocholine esterase inhibitors. Alternative Names: GSK 659032; GSK659032; GSK-659032; SB-659032; SB659032; SB 659032; GTPL7376; GTPL-7376; GTPL 7376; D05728. Grades: ≥98%. CAS No. 412950-08-4. Molecular formula: C40H38F5N3O3S. Mole weight: 735.81. | |
| Rilpivirine | A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent. Alternative Names: R 278474; TMC 278; R-278474; R278474; TMC278; TMC-278. Grades: 98%. CAS No. 500287-72-9. Molecular formula: C22H18N6. Mole weight: 366.428. | |
| Rilpivirine Z-Isomer | A stereoisomer of Rilpivirine which is a non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. Alternative Names: Benzonitrile, 4-[[4-[[4-[(1Z)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]-; 4-[[4-[[4-[(1Z)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile; (Z)-Rilpivirine; (1Z)-Rilpivirine; (Z)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile. Grades: ≥95%. CAS No. 500287-94-5. Molecular formula: C22H18N6. Mole weight: 366.42. | |
| Rilzabrutinib | Rilzabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 1.3 nM. Alternative Names: PRN1008. Grades: >98%. CAS No. 1575596-29-0. Molecular formula: C36H40FN9O3. Mole weight: 665.8. | |
| Rimonabant | Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Alternative Names: SR141716; SR 141716; SR-141716. Grades: >98%. CAS No. 168273-06-1. Molecular formula: C22H21Cl3N4O. Mole weight: 463.79. | |
| R-Indoxacarb | the R-enantiomer of Indoxacarb. Alternative Names: (4aR)-7-Chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic Acid Methyl Ester; (R)-7-Chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-inde. Grades: > 95%. CAS No. 185608-75-7. Molecular formula: C22H17F3N3O7. Mole weight: 527.84. | |
| Risdiplam | Risdiplam is an orally available SMN2 pre-mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). Alternative Names: RG7916; RG-7916; RG 7916; RO7034067. CAS No. 1825352-65-5. Molecular formula: C22H23N7O. Mole weight: 401.5. | |
| Risperidone EP Impurity B | An impurirty of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: Risperidone Z-oxime; Risperidone Z-Oxime Impurity; 2-Fluoro risperidone Z-oxime. Grades: > 95%. CAS No. 132961-05-8. Molecular formula: C23H28F2N4O2. Mole weight: 430.5. | |
| Risperidone EP Impurity D | An impurirty of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: 3-[2-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 5-Fluororisperidone. Grades: > 95%. CAS No. 1199589-74-6. Molecular formula: C23H27FN4O2. Mole weight: 410.5. | |
| Risperidone EP Impurity H | An impurirty of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: 3-[2-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; 3-[2-[4-(2,4-Difluorobenzoyl)piperidino]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 2,4-Difluorobenzoyl Risperidone Impurity; Risperidone difluoroketone. Grades: > 95%. CAS No. 158697-67-7. Molecular formula: C23H27F2N3O2. Mole weight: 415.49. | |
| Risperidone Impurity (3-Vinyl-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido[1,2-a]pyrimidin-4-one) | An impurirty of Risperidone,Risperidone is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Alternative Names: 3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one3-Ethenyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: > 95%. CAS No. 832747-59-8. Molecular formula: C11H14N2O. Mole weight: 190.25. | |
| Ritonavir EP Impurity E | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: [5S-(5R*,8R*,10R*,11R*)]-10-Hydroxy-1-[2-(1-hydroxy-1-methylethyl)-4-thiazolyl]-2-methyl-5-(1-methylethyl)-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic Acid 5-Thiazolylmethyl Ester; Hydroxy Ritonavir; Hydroxyritonavir. Grades: > 95%. CAS No. 176655-56-4. Molecular formula: C37H48N6O6S2. Mole weight: 736.96. | |
| Ritonavir EP Impurity F | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: N-[(1S,2S,4S)-2-Hydroxy-4-[(4S)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidinyl]-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester; 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-1-benzyl-2-hydroxy-4-((4S)-4-isopropyl-2,5-dioxoimidazolidin-1-yl)-5-phenylpentyl]carbamate; Thiazol-5-ylmethyl (2S,3S,5S)-3-hydroxy-5-[(S)-4-isorpopyl-2,5-dioxoimidazolidin-1-yl]-1,6-diphenylhexan-2-ylcarbamate; Hydantoin aminoalcohol Ritonavir impurity. Grades: > 95%. CAS No. 1010809-61-6. Molecular formula: C29H34N4O5S. Mole weight: 550.68. | |
| Ritonavir EP Impurity G | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: Ritonavir hydroperoxide. Grades: > 95%. CAS No. 2034136-66-6. Molecular formula: C37H48N6O7S2. Mole weight: 752.96. | |
| Ritonavir EP Impurity H | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: Hydantoin-oxazolidinone Ritonavir derivative; (4S,5S)-4-Benzyl-5-[(2S)-2-((4S)-4-isopropyl-2,5-dioxoimidazolidin-1-yl)-3-phenylpropyl]-2-oxo-1,3-oxazolidine-3-carboxylate thiazol-5-ylmethyl Ester; (4S,5S)-5-[(2S)-2-[(4S)-4-(1-methylethyl)-2,5-dioxo-1-imidazolidinyl]-3-phenylpropyl]-2-oxo-4-(phenylmethyl)-3-oxazolidinecarboxylic Acid 5-Thiazolylmethyl Ester; (4S,5S)-Thiazol-5-ylmethyl 4-Benzyl-5-[(S)-2-[(s)-4-isopropyl-2,5-dioxoimidazolidin-1-yl]-3-phenylpropyl]-2-oxooxazolidne-3-carboxylate. Grades: > 95%. CAS No. 1010809-43-4. Molecular formula: C30H32N4O6S. Mole weight: 576.68. | |
| Ritonavir EP Impurity Q | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: Thiazol-5-ylmethyl (2S,3R,5R)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido(-3-methylbutanamido)-1,6-diphenylhexan-2-ylcarbamate; Ritonavir 3R,5R-Diastereomer. CAS No. 1414933-82-6. Molecular formula: C37H48N6O5S2. Mole weight: 720.95. | |
| Ritonavir EP Impurity T | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: (2S,2'S)-N,N'-((2S,3S,5S)-3-Hydroxy-1,6-diphenylhexane-2,5-diyl)bis(2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido(-3-methylbutanamide); Ritonavir divalinyl analog. Grades: > 95%. CAS No. 869368-48-9. Molecular formula: C46H66N8O5S2. Mole weight: 875.22. | |
| Ritonavir Geo-isomer | An impurity of Ritonavir. Ritonavir is a selective HIV protease inhibitor. Alternative Names: (S)-(2S,3S,5S)-5-amino-1,6-diphenyl-2-(((thiazol-5-ylmethoxy)carbonyl)amino)hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate. Grades: > 95%. CAS No. 959315-21-0. Molecular formula: C37H48N6O5S2. Mole weight: 720.96. | |
| Rituximab | Rituximab is an anti-CD20 monoclonal antibody used for the treatment of certain autoimmune diseases and hematological cancers such as non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, etc. Its binding to CD20, which exists on the surface of immune system B cells, leads to death of cells. Uses: The treatment of non-hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, etc. Alternative Names: Immunoglobulin G1; Hsdb 7455; Hsdb-7455; Hsdb7455; Immunoglobulin G 1 (human-mouse monoclonal idec-C2B8 gamma1-chain anti-human antigen cd 20), disulfide with human-mouse monoclonal idec-C2B8 kappa-chain, dimer; Mab thera; Mabthera; Rituxan; Unii-4F4X42syq6; Retuxin. CAS No. 174722-31-7. Molecular formula: C6416H9874N1688O1987S44. Mole weight: 143859.7. | |
| Rivaroxaban EP Impurity G | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. Rivaroxaban is used to treat deep vein thrombosis and pulmonary embolism in adults. Alternative Names: 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione; Rivaroxaban Related Compound G. Grades: > 95%. CAS No. 446292-08-6. Molecular formula: C22H19N3O6. Mole weight: 421.41. | |
| Rivaroxaban EP Impurity I | An impurity of Rivaroxaban, a factor Xa (FXa) inhibitor used for the prevention and treatment of thromboembolic disorders. Alternative Names: 2-[2-[N-(5-Chlorothiophene-2-carbonyl)-4-[(5S)-5-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]anilino]ethoxy]acetic acid; Rivaroxaban Amine Impurity. CAS No. 1151893-81-0. Molecular formula: C24H21Cl2N3O7S2. Mole weight: 598.48. | |
| Rivaroxaban Open-Ring Acid Impurity | An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. Rivaroxaban is used to treat deep vein thrombosis and pulmonary embolism in adults. Alternative Names: Rivaroxaban 2-ethoxyacetic acid; Acetic acid, 2-[2-[[4-[(5S)-5-[[[(5-chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-; (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid. Grades: 95%. CAS No. 931204-39-6. Molecular formula: C19H20ClN3O6S. Mole weight: 453.90. | |
| Rivastigmine | Rivastigmine, a carbamate derivative, is a reversible cholinesterase inhibitor that is selective for the central nervous system to treat Alzheimer's Disease. Uses: Neuroprotective agents. Alternative Names: [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate; (S)-N-ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate; 713, ENA; 713, SDZ ENA; ENA 713; ENA 713, SDZ; ENA-713; ENA713; Exelon; Hydrogen Tartrate, Rivastigmine; rivastigmine; Rivastigmine Hydrogen Tartrate; RivastigmineTartrate; SDZ ENA 713; Tartrate, Rivastigmine Hydrogen; 123441-03-2; ENA 713 free base; (S)-3-(1-(dimethy. CAS No. 123441-03-2. Molecular formula: C14H22N2O2. Mole weight: 250.34. | |
| Rivastigmine EP Impurity B | An impurity of Rivastigmine. Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Alternative Names: (R,S)-3-[1-(Dimethylamino)ethyl]phenyl dimethylcarbamate; RivastigMine USP RC B; Desmethyl Rivastigmine; N-Desethyl N-Methyl rac-Rivastigmine; N,N-Dimethylcarbamic acid 3-[(RS)-1-(dimethyl amino) ethyl]phenyl ester. Grades: 95%. CAS No. 25081-93-0. Molecular formula: C13H20N2O2. Mole weight: 236.32. | |
| RK-33 | RK-33 is a first-in-class inhibitor of DDX3. It causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells, which has therapeutic use in cancers. Alternative Names: RK-33;1070773-09-9;3,7-Dihydro-3,7-bis[(4-methoxyphenyl)methyl]-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one;RK33;RK 33;3,7-Bis(4-methoxybenzyl)-3,7-dihydro-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one;5,11-Bis[(4-methoxyphenyl)methyl]-3,5,7,9,11,13-hexazatricyclo[8.3.0.02,6]trideca-1(10),2,6,8,12-pentaen-4-one;COUMZXFUZDBRCZ-UHFFFAOYSA-N;3,7-Dihydro-3,7-bis[(4-methoxyphenyl)methyl]-2H-diimidazo[4,5-d:4',5'-f][1,3]diazepin-2-one;;SCHEMBL1313539;CHEMBL1672984;GLXC-10845;EX-A4211;VSB77309;RK-33?;s8246;AKOS032945047;CCG-268980;CS-5880;AC-33039;BS-14382;CID 46184988;DA-57464;HY-100455;D84049;5,11-bis[(4-methoxyphenyl)methyl]-3,5,7,9,11,13-hexaazatricyclo[8.3.0.0(2),?]trideca-1(10),2,6,8,12-pentaen-4-one. CAS No. 1070773-09-9. Molecular formula: C23H20N6O3. Mole weight: 428.44. | |
| RLY-2608 | RLY-2608 is a first-in-class allosteric mutant-selective inhibitor of PI3Kα. RLY-2608 was shown that elicited objective tumor responses in two patients diagnosed with advanced hormone receptor-positive breast cancer with kinase or helical domain PIK3CA mutations, with no observed WT PI3Kα-related toxicities. Alternative Names: RLY 2608; RLY2608. Grades: 98% by HPLC. CAS No. 2733573-94-7. Molecular formula: C29H14ClF5N6O2. Mole weight: 608.9. | |
| RMC-5552 | RMC-5552 is a potent and selective inhibitor of mTORC1. It inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. Anticancer activity. Grades: 98%. CAS No. 2382768-62-7. Molecular formula: C93H136N10O24. Mole weight: 1778.13. | |
| RMC-6236 | RMC-6236 is a RASMULTI inhibitor that targets the active form of RAS proteins with a wide range of different mutations. Alternative Names: RMC 6236; RMC6236; Ras-IN-2; RAS Inhibitor A122. Grades: 98% by HPLC. CAS No. 2765081-21-6. Molecular formula: C44H58N8O5S. Mole weight: 811.0. | |
| RMC-6272 | RMC-6272 is a bi-steric mTORC1-selective inhibitor. It exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. Alternative Names: RM-006. CAS No. 2382769-46-0. Molecular formula: C95H141FN6O27S. Mole weight: 1850.22. | |
| R-Morinidazole | R-Morinidazole is the R enantiomer of Morinidazole, wich is a novel 5-nitroimidazole antimicrobial drug. It undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. It is used in the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria. Uses: R-morinidazole is used in the treatment of bacterial infections including appendicitis and pelvic inflammatory disease (pid) caused by anaerobic bacteria. Alternative Names: (R)-1-(2-Methyl-5-nitro-1H-imidazol-1-yl)-3-morpholinopropan-2-ol;(2R)-1-(2-methyl-5-nitroimidazol-1-yl)-3-morpholin-4-ylpropan-2-ol;Morinidazole R enantiomer. Grades: >98%. CAS No. 898230-59-6. Molecular formula: C11H18N4O4. Mole weight: 270.29. | |
| (R)-N1-Boc-1,2-propanediamine | (R)-N1-Boc-1,2-propanediamine (CAS# 333743-54-7) is a useful research chemical compound. Alternative Names: N-[(2R)-2-aminopropyl]carbamic acid tert-butyl ester; tert-butyl N-[(2R)-2-aminopropyl]carbamate. CAS No. 333743-54-7. Molecular formula: C8H18N2O2. Mole weight: 174.24. | |
| R-Naproxen | A metabolite of Naproxen, which is a non-selective COX inhibitor. Alternative Names: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid; (R)-(-)-6-Methoxy-α-methyl-2-naphthaleneacetic acid. Grades: > 95%. CAS No. 23979-41-1. Molecular formula: C14H14O3. Mole weight: 230.27. | |
| RO-0335 | RO-0335 is a novel diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. Alternative Names: RO0335; RO 0335; N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroBenzeneacetamide. Grades: 99%. CAS No. 867365-76-2. Molecular formula: C21H13BrCl2FN3O4S. Mole weight: 573.21. | |
| Ro 08-2750 | Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM). NGF has potential effects on matrix turnover activity and influences the catabolic / anabolic balance of IVD cells in an adverse way that may potentiate IVD degeneration. Anti-NGF treatment might be beneficial to ameliorate progressive tissue breakdown in IVD degeneration and may lead to pain relief. Alternative Names: Ro08-2750; Ro-08-2750; Ro 082750; Ro-82750; Ro082750; 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde. Grades: 98%. CAS No. 37854-59-4. Molecular formula: C13H10N4O3. Mole weight: 270.25. | |
| RO4929097 | RO4929097, a small-molecule inhibitor of γ secretase (IC50 = 4 nM, EC50=5 nM), inhibits cellular processing of Aβ40 (EC50 = 14 nM) and Notch (EC50 = 5 nM). It was shown to decrease the levels of Notch transcriptional target HES1 in human primary melanoma cell lines. Uses: Enzyme inhibitors. Alternative Names: RO-4929097; 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide. Grades: >98%. CAS No. 847925-91-1. Molecular formula: C22H20F5N3O3. Mole weight: 469.4. | |
| RO5045337 | RO5045337, also known as R7112, RG7112, is a MDM2 antagonist with potential antineoplastic activity. RO5045337 binds to MDM2, thereby preventing the binding of the MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53. By preventing this MDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited and the transcriptional activity of p53 is restored, which may result in the restoration of p53 signaling and thus the p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger protein, is a negative regulator of the p53 pathway; often overexpressed in cancer cells, it has been implicated in cancer cell proliferation and survival. Alternative Names: RG7112; RG 7112; RG-7112; RO5045337; RO 5045337; RO-5045337. Grades: 98%. CAS No. 939981-39-2. Molecular formula: C38H48Cl2N4O4S. Mole weight: 727.786. | |
| RO-5256390 | RO-5256390 is a novel selective full agonist of the trace amine-associated receptor 1 (TAAR1). It blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties. It promotes vigilance in rats and shows pro-cognitive and antidepressant-like properties in rodent and primate models. It may improve not only the positive symptoms but also the negative symptoms and cognitive deficits, without causing adverse effects such as motor impairments or weight gain. It may be used as treatment of cocaine addiction. Uses: Ro-5256390 has antipsychotic-like properties. it may be used as treatment of cocaine addiction. Alternative Names: RO5256390; RO 5256390; RO-5256390; (S)-4-((S)-2-phenylbutyl)-4,5-dihydrooxazol-2-amine;(4S)-4-[(2S)-2-phenylbutyl]-4,5-dihydro-1,3-oxazol-2-amine. Grades: >98 %. CAS No. 1043495-96-0. Molecular formula: C13H18N2O. Mole weight: 218.30. | |
| Ro 5-3335 | Ro 5-3335, a benzodiazepine, is a core binding factor (CBF) leukemia inhibitor. It is highly active in vitro (IC50 = 0.1-1.0 microM [corrected]) against HIV-1 viruses of AIDS resistant or non-resistant to zidovudine (AZT). Alternative Names: Ro 5-3335; Ro-5-3335; Ro 5 3335; 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-pyrrol-2-yl- (7CI,8CI); NSC 66020; NSC66020; NSC-66020. Grades: ≥98% by HPLC. CAS No. 30195-30-3. Molecular formula: C13H10ClN3O. Mole weight: 259.69. | |
| Rocaglamide J | Rocaglamide J. Alternative Names: Aglafoline; Methylrocaglate; AGLAFOLIN; CHEBI:65374; CMLDBU00002646; 143901-35-3. Grades: 95%. CAS No. 147059-47-0. Molecular formula: C28H28O8. Mole weight: 492.51712. | |
| Rocuronium bromide | Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant. Alternative Names: ORG 9426; ORG-9426; ORG9426. Grades: >98%. CAS No. 119302-91-9. Molecular formula: C32H53N2O4.Br. Mole weight: 609.68. | |
| Rocuronium Bromide EP Impurity B (Impurity 15) | An impurity of Rocuronium.Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(4-morpholinyl)androstan-16-yl]-1-(2-propen-1-yl)pyrrolidinium Bromide. Grades: > 95%. CAS No. 122483-73-2. Molecular formula: C34H55N2O5. Br. Mole weight: 651.73. | |
| Rocuronium Bromide Impurity 17 (EP impurity D) | An impurity of Rocuronium.Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 3-Acetyl-17-deacetyl Rocuronium Bromide;1-[(2β,3α,5α,16β,17β)-3-(Acetyloxy)-17-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-63-5. Molecular formula: C32H53N2O4. Br. Mole weight: 609.69. | |
| Rocuronium EP Impurity A | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-Acetate; (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 17-Acetate; Desallyl Rocuronium. Grades: 95%. CAS No. 119302-24-8. Molecular formula: C29H48N2O4. Mole weight: 488.72. | |
| Rocuronium EP Impurity C | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 17-Desacetyl Rocuronium Bromide; 1-[(2β,3α,5α,16β,17β)-3,17-Dihydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide. Grades: > 95%. CAS No. 119302-86-2. Molecular formula: C30H51N2O3.Br. Mole weight: 567.65. | |
| Rocuronium EP Impurity H | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 1,2-Dehydro-3-oxo Rocuronium Bromide; Rocuronium Bromide Impurity 21; 1-[(5α,16β,17β)-17-(Acetyloxy)-2-(4-morpholinyl)-3-oxoandrost-1-en-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-67-9. Molecular formula: C32H49N2O4.Br. Mole weight: 605.65. | |
| R-(-)-O-Desmethyl-Venlafaxine | R-(-)-O-Desmethyl-Venlafaxine is a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. CAS No. 142761-11-3. Molecular formula: C16H25NO2. Mole weight: 263.38. | |
| Rofecoxib | Rofecoxib is a COX-2 inhibitor (IC50s = 26 nM and > 50 μM in human osteosarcoma cells). Uses: Cyclooxygenase 2 inhibitors. Alternative Names: MK966; MK966; MK 966; MK0966; MK0966; MK 0966; Rofecoxib; brand name: Vioxx; Ceoxx; Ceeoxx. 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. Grades: > 95%. CAS No. 162011-90-7. Molecular formula: C17H14O4S. Mole weight: 314.4. | |
| Roflumilast Impurity D | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: Benzoic acid, 3-(cyclopropylmethoxy)-4-hydroxy-. CAS No. 1243391-44-7. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Roflumilast N-Oxide | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl- methoxybenzamide; 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide. Grades: > 95%. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast Related Compound A | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as an antiasthmatic agent. Alternative Names: 4-O-Des(difluoromethyl) Roflumilast; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: > 95%. CAS No. 475271-62-6. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.20. | |
| Roflumilast Related Compound B | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: 3-O-Decyclopropyl Roflumilast; Roflumilast metabolite M05; 3-(Hydroxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. CAS No. 1391052-76-8. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.11. | |
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