BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| SAR131675 | SAR131675 dose dependently inhibits the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC50 of about 20 nM. Alternative Names: (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 1,8-Naphthyridine-3-carboxamide, 2-amino-1-ethyl-1,4-dihydro-7-[(3R)-3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl]-N-methyl-4-oxo-. Grades: >98%. CAS No. 1433953-83-3. Molecular formula: C18H22N4O4. Mole weight: 358.39. |  |
| Saracatinib | Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Specifically, Saracatinib inhibits Src kinase-mediated osteoclast bone resorption. Uses: Antineoplastic agents. Alternative Names: AZD 0530; AZD-0530; AZD0530. Grades: >98%. CAS No. 379231-04-6. Molecular formula: C27H32ClN5O5. Mole weight: 542.03. | |
| Sarafotoxin S6a | Sarafotoxin S6a is an endothelin receptor agonist (EC50 = 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta, respectively). CAS No. 126738-34-9. Molecular formula: C105H156N28O34S5. Mole weight: 2514.85. | |
| Sarafotoxin S6b | Sarafotoxin S6b is a non-selective endothelin receptor agonist with vasoconstrictor activity. CAS No. 116303-65-2. Molecular formula: C110H159N27O34S5. Mole weight: 2564. | |
| Saridegib | Saridegib is an orally bioavailable, cyclopamine-derived inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity, one of smoothened (Smo) inhibitors. Alternative Names: SARIDEGIB; IPI-926 Hydrochloride; Patidegib. CAS No. 1037210-93-7. Molecular formula: C29H48N2O3S. Mole weight: 504.77. | |
| Saringosterol | Saringosterol is a natural compound which can be isolated from Sargassum, Tydemania expeditionis, etc. Grades: 95%. CAS No. 6901-60-6. Molecular formula: C29H48O2. Mole weight: 428.69. | |
| Sarm-Nutlin Protac | SARM-nutlin PROTAC is a MDM2-based PROTAC consisting of a non-steroidal androgen receptor ligand (SARM) and a Nutlin, linked via a PEG-based linker. Alternative Names: (S)-3-(4-(1-(4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-amido)phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide; 14-(4-{[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazol-1-yl]carbonyl}-2-oxo-1-piperazinyl)-N-{4-[(2S)-2-hydroxy-2-methyl-3-{[4-nitro-3-(trifluoromethyl)phenyl]amino}-3-oxopropoxy]phenyl}-13-oxo-3,6,9-trioxa-12-azatetradecan-1-amide; 1-Piperazineacetamide, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-N-[2-[2-[2-[2-[[4-[(2S)-2-hydroxy-2-methyl-3-[[4-nitro-3-(trifluoromethyl)phenyl]amino]-3-oxopropoxy]phenyl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethyl]-2-oxo-. Molecular formula: C57H61Cl2F3N8O14. Mole weight: 1208.36. | |
| Saroglitazar | Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment of diabetic dyslipidemia and hypertriglyceridemia with Type 2 diabetes mellitus not controlled by statin therapy. Alternative Names: Lipaglyn; ZY-H1; (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid. Grades: ≥98%. CAS No. 495399-09-2. Molecular formula: C25H29NO4S. Mole weight: 439.57. | |
| Saroglitazar (Magnesium) | Saroglitazar magnesium is a dual PPAR agonist with potent predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. The first glitazar to be granted marketing authorization in India. CAS No. 1639792-20-3. Molecular formula: C50H56MgN2O8S2. Mole weight: 901.43. | |
| S-(+)-Atomoxetine Hydrochloride | S-(+)-Atomoxetine Hydrochloride is an enatiomer of Atomoxetine, which is a selective norepinephrine (NE) reuptake inhibitor for the treatment of attention-deficit hyperactivity disorder (ADHD). Uses: The enatiomer of atomoxetine, a norepinephrine uptake blocker. Alternative Names: (γS)-N-Methyl-γ-(2-methylphenoxy)benzenepropanamine Hydrochloride; (S)-(+)-Tomoxetine Hydrochloride; (S)-Tomoxetine Hydrochloride; LY 139602; Atomoxetine EP Impurity B; Ent S-(+)-atomoxetine hydrochloride. Grades: ≥95%. CAS No. 82857-39-4. Molecular formula: C17H22ClNO. Mole weight: 291.82. | |
| SB 202190 hydrochloride | SB 202190 is a potent, selective, and cell-permeable inhibitor of p38 MAP kinases, effective against p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. It inhibits p38 MAP kinases, resulting in blockade of tumor necrosis factor alpha (TNF-alpha) and interleukin-1beta (IL-1beta) production in monocytes. Alternative Names: SB 202190 HCl; 4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol hydrochloride. Grades: ≥98%. CAS No. 350228-36-3. Molecular formula: C20H14FN3O·HCl. Mole weight: 367.8. | |
| SB 204990 | SB 204990 is a prodrug of SB 201076, which is an ATP citrate lyase (ACLY) inhibitor. SB 204990 inhibits cholesterol and fatty acid synthesis in a dose-dependent manner in HepG2 cells. SB 204990 was shown to decrease plasma levels of the lipoproteins VLDL, LDL, and HDL in dogs. Alternative Names: SB-204990; SB 204990; SB204990; (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid. Grades: ≥98% by HPLC. CAS No. 154566-12-8. Molecular formula: C18H22Cl2O5. Mole weight: 389.27. | |
| SB-334867 hydrochloride | SB-334867 hydrochloride is the first non-peptide selective antagonist of orexin receptor subtype OX1 and shows in vivo activity following ip dosing. Alternative Names: SB-334867 HCl; Urea, N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-, hydrochloride (1:1); N-(2-methyl-6-benzoxazolyl)-N'-1,5-napthyridin-4-yl)urea monohydrochloride. Grades: 98%. CAS No. 249889-64-3. Molecular formula: C17H14ClN5O2. Mole weight: 355.78. | |
| SB431542 | SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. Uses: Reprogramming, differentiation. Alternative Names: SB431542; SB-431542; SB 431542. Grades: 98%. CAS No. 301836-41-9. Molecular formula: C22H16N4O3. Mole weight: 384.39. | |
| SB-674042 | SB-674042 is potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM), by binding with high affinity to OX1R and mediates intracellular calcium flux in OX1R-expressing cells. Uses: Potent and selective non-peptide orexin ox1 receptor antagonist. Alternative Names: SB 674042; SB-674042; SB674042; [5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone. Grades: ≥98%. CAS No. 483313-22-0. Molecular formula: C24H21FN4O2S. Mole weight: 448.51. | |
| SB-743921 HCl | SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis. Alternative Names: SB-743921; SB 743921; SB743921. Grades: >98%. CAS No. 940929-33-9. Molecular formula: C31H34Cl2N2O3. Mole weight: 553.524. | |
| SB 751689A | SB 751689A. CAS No. 702686-96-2. Molecular formula: C25H32ClF2NO4. Mole weight: 484.00. | |
| SBE-β-CD | SBE-β-CD, also called as Sulfobutylether beta-cyclodextrin sodium, is a β-Cyclodextrin derivative with sulfobutyl ether groups and sodium ions substituted designed to optimize the drug properties. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation. Alternative Names: SBE4-b-CyD; SBECD; Betadex Sulfobutyl Ether Sodium; Sulfobutyl Ether Beta-Cyclodextrin; Sulfobutyl Ether-Beta-Cyclodextrin; Sodium Sulphobutylether-Beta-Cyclodextrin. Grades: 95%. CAS No. 182410-00-0. | |
| SBI-425 | SBI-425 is a potent, selective and oral bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor with IC50 of 0.016 μM. In vivo studies demonstrate that SBI-425 suppresses aortic calcification in mice that overexpress TNAP in smooth muscle cells, resulting in reduced aortic calcification and increased life-span. Alternative Names: 5-(5-Chloro-2-methoxyphenylsulfonamido)nicotinamide. Grades: 99%. CAS No. 1451272-71-1. Molecular formula: C13H12ClN3O4S. Mole weight: 341.77. | |
| SBI-553 | SBI-553 is a brain-penetrant allosteric modulator of neurotensin receptor 1 (NTSR1). SBI-553 reduces stimulant effects without the side effects of unbiased NTSR1 agonists. Alternative Names: SBI 553; SBI553. CAS No. 1849603-72-0. Molecular formula: C26H31FN4O2. Mole weight: 450.5. | |
| SC75741 | SC75741 is a potent NF-κB inhibitor (EC50=200 nM). Alternative Names: SC 75741; SC-75741; 4-Thiazolecarboxamide, N-(6-benzoyl-1H-benzimidazol-2-yl)-2-(1-thieno[3,2-d]pyrimidin-4-yl-4-piperidinyl)-. Grades: 98%. CAS No. 913822-46-5. Molecular formula: C29H23N7O2S2. Mole weight: 565.67. | |
| SCH-50911 | CH-50911 is a selective GABA-B antagonist with IC50 value of 1.1 μM. It is developed by Schering-Plough Corporation. CH-50911 is often used in pharmacology research and it also acts as an anticonvulsant under normal conditions. Preclinical trials for Absence seizures and Cognition disorders in USA were discontinued. Uses: Absence epilepsy; cognition disorders. Alternative Names: SCH-50911; SCH 50911; SCH50911; (S)-2-(5,5-dimethylmorpholin-2-yl)acetic acid. Grades: 98%. CAS No. 733717-87-8. Molecular formula: C8H15NO3. Mole weight: 173.21. | |
| SCH 527123 | A potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively. Alternative Names: 2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide; SCH527123; SCH-527123; SCH 527123; MK-7123; MK7123; MK 7123; PS291822; PS-291822; PS 291822; Navarixin monohydrate; Navarixin. CAS No. 473727-83-2. Molecular formula: C21H23N3O5. Mole weight: 397.42. | |
| SCH 546738 | SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist with Ki of 0.4 nM. Alternative Names: SCH546738; SCH 546738; SCH-546738; 3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide. CAS No. 906805-42-3. Molecular formula: C23H31Cl2N7O. Mole weight: 492.44. | |
| Schizophyllan | Schizophyllan is a natural polysaccharide derived from the fungus Schizophyllum commune. It is a type of beta-glucan with a unique structure and a variety of biological and functional properties, making it of interest in multiple fields, including medicine, biotechnology, and food industries. Schizophyllan is an immunostimulant commonly used in cancer treatment in combination with other antineoplastic drugs. Alternative Names: Sonifilan; Sizofiran; SPG; β(1-3,1-6)-glucan; Schizophylan; Schizophyllane; Shizophyllan; Sixofilan; Sizofilan; Sizofuran. Grades: 85%. CAS No. 9050-67-3. | |
| Scleroglucan polysaccharide | Scleroglucan polysaccharide is a widely utilized compound product, exhibiting paramount significance in the research of diverse diseases, notably in the realm of targeted drug delivery systems. Its distinctive attributes facilitate the proficient encapsulation and precise discharge of pharmaceuticals. Alternative Names: Scleroglucan; Actigum C 56DF; Actigum CS 11; Actigum CS 6; Actigum CS 6DF; Actigum CS II-L; Amigel; Amigum; Betasizofiran; Biovis; Clearogel CS 11; Clearogel CS 11D; CS 11; PM-II; Polytetran; Polytran FS; Scleroglucan gum; Sclerogum; Sclerosan; Sclerotan; Sclerotium gum; Sclerotium rolfsii gum. CAS No. 39464-87-4. | |
| Scutellaria Baicalensis Root Extract | Scutellaria Baicalensis Root Extract is a fully water-soluble plant cosmetic raw material obtained from the dried root of Scutellaria baicalensis Georgi. It mainly contains two flavonoid active ingredients, baicalin and baicalein, which has strong biological activity and is a multi-effect cosmetic additive. Grades: 95%. CAS No. 94279-99-9. Molecular formula: C20H26N2. Mole weight: 294.434. | |
| Scytonemin | Scytonemin is a biological pigment synthesized by many strains of cyanobacteria. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin (at 3 and 4 μM concentration) inhibited multiple myeloma cell growth associated with downregulation of the activity of Plk1 but no effect on the expression of Plk1. Scytonemin, representing a novel Plk1 inhibitor, induced the inhibition of cell growth and cell cycle arrest in multiple myeloma cells by specifically decreasing Plk1 activity. Taken together, scytonemin is a promising novel agent for the treatment of multiple myeloma. Alternative Names: (3E,3'E)-3,3'-bis(4-hydroxybenzylidene)-[1,1'-bi(cyclopenta[b]indole)]-2,2'(3H,3'H)-dione; (1,1'-Bicyclopent(b)indole)-2,2'(3H,3'H)-dione, 3,3'-bis((4hydroxyphenyl)methylene)-3,3'-Bis((4-hydroxyphenyl)methylene)-(1,1'-bicyclopent(b)indole)-2,2'(3H,3'H)-dione. Grades: 98%. CAS No. 152075-98-4. Molecular formula: C36H20N2O4. Mole weight: 544.56. | |
| SD-06 | SD-06 is an inhibitor of p38α (IC50=170 nM). It is developed for the treatment of arthritis. Alternative Names: SD 0006; SD-0006; SD0006; SD-06; SD-06; SD-06. CAS No. 271576-80-8. Molecular formula: C20H20ClN5O2. Mole weight: 397.86. | |
| SD-282 | SD-282 is an ATP-competitive inhibitor of p38 kinase. SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation. SD-282 may have potential therapeutic value of p38alpha MAPK inhibitors in the treatment of aberrant pain sensitivity produced by diabetes. Alternative Names: SD282; SD 282; SCIO-282; SCIO 282; SCIO282; rac-Talmapimod. CAS No. 309915-13-7. Molecular formula: C27H30ClFN4O3. Mole weight: 513.00. | |
| S-Dihydrodaidzein | S-Dihydrodaidzein is a natural product found in Pericopsis mooniana. Alternative Names: S-2,3-Dihydro-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-Benzopyran-4-one; (S)-7-Hydroxy-3-(4-hydroxyphenyl)chroman-4-one; (S)-dihydrodaidzein; (S)-4',7-dihydroxyisoflavanone; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-3-(4-hydroxyphenyl)-, (3S)-; (3S)-7-Hydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one. Grades: ≥95%. CAS No. 879559-75-8. Molecular formula: C15H12O4. Mole weight: 256.25. | |
| SDMA | An endogenous inhibitor of nitric oxide (NO) synthase activity. Alternative Names: (2S)-2-amino-5-[(N,N'-dimethylcarbamimidoyl)amino]pentanoic acid; guanidino-N(1),N(2)-dimethylarginine; N(G1),N(G2)-dimethylarginine; N,N'-dimethylarginine; NG,N'G-dimethyl-L-arginine; omega-N(G),N'(G)-dimethylarginine; sDMA arginine; symmetric dimethylarginine. CAS No. 30344-00-4. Molecular formula: C8H18N4O2. Mole weight: 202.25. | |
| Sebaconitrile | Sebaconitrile. Alternative Names: Octane-1,8-dicarbonitrile; Oktamethylendikyanid; Sebacoitrile; OCTAMETHYLENE DICYANIDE; SEBACIC ACID DINITRILE; SEBACONITRILE; 1,8-DICYANOOCTANE; DECANE-1,10-DINITRILE. Grades: >98.0%(GC). CAS No. 1871-96-1. Molecular formula: C10H16N2. Mole weight: 164.25. | |
| SEBUTHYLAZINE-2-HYDROXY | SEBUTHYLAZINE-2-HYDROXY. Alternative Names: SEBUTHYLAZINE-2-HYDROXY. Grades: 95%. CAS No. 33124-61-7. Molecular formula: C9H17N5O. Mole weight: 211.26. | |
| sec-Butylchlorodimethylsilane | sec-Butylchlorodimethylsilane. Alternative Names: Silane, chlorodimethyl(1-methylpropyl)-; Chlorodimethyl(1-methylpropyl)silane; Chlorodimethyl-sec-butylsilane; 2-Butyldimethylchlorosilane. Grades: 95%. CAS No. 60090-96-2. Molecular formula: C6H15ClSi. Mole weight: 150.72. | |
| Seco Rapamycin | Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR. Alternative Names: Secorapamycin A. CAS No. 147438-27-5. Molecular formula: C51H79NO13. Mole weight: 914.17. | |
| Secorapamycin B | Secorapamycin B is an impurity of Rapamycin. Rapamycin is a macrolide compound. It inhibits activation of T cells and B cells by reducing the production of interleukin-2. Rapamycin can be used to coat coronary stents and prevent organ transplant rejection. Alternative Names: 34-Hydroxy Sirolimus; 34-Hydroxy Rapamycin. CAS No. 185107-79-3. Molecular formula: C51H81NO14. Mole weight: 932.19. | |
| Seco Rapamycin (sodium salt) | Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin which is a natural macrolide immunosuppressant. Seco-rapamycin inhibits the ChT-L (D) and PGPH (E) peptidases, and activate the T-L (F) peptidase and poorly activates mTOR. IC50: ChT-L. Uses: A decomposition product of rapamycin (r124000). Alternative Names: seco Rapamycin Sodium Salt. Grades: > 95%. CAS No. 148554-65-8. Molecular formula: C51H78NNaO13. Mole weight: 936.15. | |
| Sedoheptulose-7-phosphate | Sedoheptulose-7-phosphate is a quintessential compound, functioning in studying sundry metabolic anomalies and maladies such as diabetes, obesity and distinctive hereditary afflictions. Alternative Names: (2,3,4,5,7-pentahydroxy-6-oxo-heptoxy)phosphonic acid; D-altro-hept-2-ulose 7-phosphate. Grades: ≥98%. CAS No. 2646-35-7. Molecular formula: C7H15O10P. Mole weight: 290.16. | |
| Sedoheptulose anhydride monohydrate | Sedoheptulose anhydride monohydrate, a promising biomedical substance, stands at the forefront of investigating metabolic pathways and unraveling the intricate involvement of sedoheptulose in cellular processes. Alternative Names: 2,7-Anhydro-b-D-altro-heptulopyranose; Sedoheptulosan. CAS No. 469-90-9. Molecular formula: C7H14O7. Mole weight: 210.18. | |
| SELACHYL ALCOHOL | SELACHYL ALCOHOL. Alternative Names: A-OLEYL GLYCERYL ETHER; SELACHYL ALCOHOL; (Z)-3-(9-octadecenyloxy)propane-1,2-diol; 1-O-[(Z)-9-Octadecenyl]glycerol; 3-[(Z)-9-Octadecenyloxy]-1,2-propanediol; 3-[[(Z)-9-Octadecenyl]oxy]propane-1,2-diol; Einecs 209-787-7; Glyceryl monooleyl ether. CAS No. 593-31-7. Molecular formula: C21H42O3. Mole weight: 342.56. | |
| Seladelpar | Seladelpar is a selective peroxisome proliferator-activated receptor -δ receptor agonist. Phase II clinical trials for the treatment of Hyperlipidaemia, Hyperlipoproteinaemia type IIa and Primary biliary cirrhosis were on-going. Alternative Names: MBX8025; RWJ800025; MBX 8025; RWJ 800025; MBX-8025; RWJ-800025; (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetic acid. Grades: 98%. CAS No. 851528-79-5. Molecular formula: C21H23F3O5S. Mole weight: 444.46. | |
| Selenocystamine | Selenocystamine. Alternative Names: Selenocystamine. CAS No. 2697-61-2. Molecular formula: C4H12N2Se2. Mole weight: 246.07. | |
| Selenocystamine dihydrochloride | Selenocystamine dihydrochloride. Alternative Names: 2,2'-Diselanediyldiethanamine dihydrochloride; Ethanamine, 2,2'-diselenobis-, dihydrochloride; selenocystamine hydrochloride; 2,2'-(1,2-diselanediyl)diethanamine dihydrochloride; 2-[(2-aminoethyl)diselanyl]ethan-1-amine dihydrochloride. Grades: ≥95%. CAS No. 3542-13-0. Molecular formula: C4H14Cl2N2Se2. Mole weight: 318.99. | |
| Selenomethionine | Selenomethionine is an essential nutrient that may have a role in other biologically active compounds, especially vitamin E and the enzyme formic dehydrogenase. Alternative Names: DL-Selenomethionine; Selenomethionine; Seleno-DL-methionine; (+-)-Selenomethionine; 2578-28-1; 2-amino-4-(methylselanyl)butanoicacid. Grades: 95%. CAS No. 1464-42-2. Molecular formula: C5H11NO2Se. Mole weight: 196.11. | |
| Selinexor | Selinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein / exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells. Alternative Names: KPT-330; KPT 330; KPT330; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-; Xpovio; (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide. Grades: ≥95%. CAS No. 1393477-72-9. Molecular formula: C17H11F6N7O. Mole weight: 443.31. | |
| Selpercatinib | Selpercatinib is a selective RET inhibitor with antineoplastic activity. It inhibits proliferation of cancer cells containing RET mutations or gene fusions. It is indicated for the treatment of non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC) and other thyroid cancer tumors. Alternative Names: LOXO-292; LOXO292; LOXO 292; ARRY-192; ARRY192; ARRY 192. CAS No. 2152628-33-4. Molecular formula: C29H31N7O3. Mole weight: 525.6. | |
| Seltorexant hydrochloride | Seltorexant hydrochloride is an orally active and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride can cross the blood-brain barrier and quickly occupy OX2R binding sites in the rat brain. Alternative Names: JNJ-42847922 hydrochloride. Grades: 99%. CAS No. 1293284-49-7. Molecular formula: C21H23ClFN7O. Mole weight: 443.91. | |
| Selumetinib | Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886. Grades: >98%. CAS No. 606143-52-6. Molecular formula: C17H15BrClFN4O3. Mole weight: 457.684. | |
| Selumetinib sulfate | Selumetinib is a selective, non-ATP-competitive oral MEK1/2 inhibitor. Selumetinib also inhibits ERK1/2 phosphorylation. Alternative Names: AZD-6244 hydrogen sulfate; Selumetinib (sulfate); AZD-6244 Hyd-Sulfate; NSC-748727; AZD6244 sulfate; ARRY-142886 sulfate. Grades: 99%. CAS No. 943332-08-9. Molecular formula: C17H17BrClFN4O7S. Mole weight: 555.76. | |
| Semaglutide-[d15] | Semaglutide-[d15] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: Semaglutide-d15; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu(D7)-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H276D15N45O59. Mole weight: 4128.73. | |
| Semaglutide Impurity 16 | Semaglutide Impurity 16 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: Glycine, N-L-α-glutamyl-, 5-(1,1-dimethylethyl) ester; Glutaramic acid, 4-amino-N-(carboxymethyl)-, 1-tert-butyl ester, L-; (S)-(2-amino-5-(tert-butoxy)-5-oxopentanoyl)glycine; H-Glu(OtBu)-Gly-OH; ({(2S)-2-Amino-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoyl}amino)acetic acid. CAS No. 23406-82-8. Molecular formula: C11H20N2O5. Mole weight: 260.29. | |
| Semaglutide Impurity 1 ((Trp25-hydroxybenzyl)-Semaglutide) | Semaglutide Impurity 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-(L-tryptophyl-hydroxybenzyl)-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-(Trp-hydroxybenzyl)-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C194H297N45O60. Mole weight: 4219.77. | |
| Semaglutide Impurity 3 (P3 Semaglutide) | Semaglutide Impurity 3 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C126H206N30O36. Mole weight: 2717.21. | |
| Semaglutide intermediate | Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: (S)-21,39-di-tert-butyl 1-(2,5-dioxopyrrolidin-1-yl) 9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate; 17-((S)-1-tert-Butoxycarbonyl-3-{2-[2-({2-[2-(2,5-dioxopyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]-ethylcarbamoyl}propylcarbamoyl)heptadecanoic acid tert-butyl ester; Octadecanoic acid, 18-[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-22-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4,13,22-trioxo-8,11,17,20-tetraoxa-5,14-diazadocos-1-yl]amino]-18-oxo-, 1,1-dimethylethyl ester; Bis(2-methyl-2-propanyl) (22S)-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazatetracontane-22,40-dicarboxylate; tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu. Grades: ≥95%. CAS No. 1118767-15-9. Molecular formula: C47H82N4O15. Mole weight: 943.19. | |
| Semaglutide-[Phe-d5] | Semaglutide-[Phe-d5] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: H-His-Aib-Glu-Gly-Thr-Phe(D5)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D5; Semaglutide-d5. Molecular formula: C187H286D5N45O59. Mole weight: 4118.67. | |
| Semaglutide-[Phe-d8] | Semaglutide-[Phe-d8] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: H-His-Aib-Glu-Gly-Thr-Phe(D8)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D8; Semaglutide-d8. Molecular formula: C187H283D8N45O59. Mole weight: 4121.69. | |
| Semaglutide related compound 1 | Semaglutide related compound 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: Semaglutide SZ Impurity 1; Semaglutide Iso Asp Impurity; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Iso-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H291N45O59. Mole weight: 4113.64. | |
| Semaglutide-[Val-d8] Tetratrifluoroacetate | Semaglutide-[Val-d8] Tetratrifluoroacetate is the labelled salt of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Alternative Names: Semaglutide-d8 Tetratrifluoroacetate; L-histidyl-2-methylalanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-d8-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-a-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-Glycine, trifluoroacetic acid (1:4); H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.4TFA. Molecular formula: C187H283D8N45O59.4C2HF3O2. Mole weight: 4577.78. | |
| Semapimod | An investigational new drug in a clinical trial for the treatment of Crohn's Disease. It exhibits anti-inflammatory, anti-cytokine, immunomodulatory, antiviral and antimalarial activities. Alternative Names: CNI-1493; CNI 1493; CNI1493; N,N'-bis[3,5-bis[(E)-N-(diaminomethylideneamino)-C-methylcarbonimidoyl]phenyl]decanediamide. CAS No. 352513-83-8. Molecular formula: C34H52N18O2. Mole weight: 744.91. | |
| Semapimod hydrochloride | Semapimod (INN), formerly known as CNI-1493, is a cytokine inhibitor. Semapimod is an investigational new drug which has anti-inflammatory, anti-cytokine, immunomodulatory, antiviral and antimalarial properties. Structurally, semapimod is synthetic guanylhydrazone mitogen-activated protein kinase blocker, as a potential treatment for Crohn's disease and other inflammatory conditions. Clinical trials of Semapimod started in 2001. Alternative Names: CNI-1493; CNI 1493; CNI1493; AXD455; AXD 455; AXD-455; AIDS121302; AIDS-121302; AIDS 121302. Grades: >98%. CAS No. 164301-51-3. Molecular formula: C34H56Cl4N18O2. Mole weight: 890.746. | |
| Semduramicin,30-hydroxy-5-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)- (9CI) | Semduramicin,30-hydroxy-5-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)- (9CI). Grades: 95%. CAS No. 98824-17-0. Molecular formula: C52H88 O19. Mole weight: 1017.20. | |
| Semen Ziziphi Spinosae Extract | Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc. Grades: 10:1. | |
| Se-(Methyl)selenocysteine hydrochloride | Se-(Methyl)selenocysteine hydrochloride is an anticancer agent that inhibits cell cycle proliferation and induces apoptosis. Alternative Names: (2R)-2-amino-3-methylselanylpropanoic acid hydrochloride; (R)-2-Amino-3-(methylselanyl)propanoic acid hydrochloride; Se-MSC. Grades: >95%. CAS No. 863394-07-4. Molecular formula: C4H10ClNO2Se. Mole weight: 218.55. | |
| Semicarbazide | Semicarbazide. Alternative Names: Carbamylhydrazine. CAS No. 57-56-7. Molecular formula: CH5N3O. Mole weight: 75.07. | |
| Senecionine N-Oxide | Senecionine N-Oxide is an alkaloid isolated from Senecio vulgaris showing anti-cancer activity. Alternative Names: Senecionine oxide; 12-Hydroxysenecionan-11,16-dione 4-oxide. Grades: 98%. CAS No. 13268-67-2. Molecular formula: C18H25NO6. Mole weight: 351.17. | |
| Senicapoc | Senicapoc, previously called as ICA 17043, is a small organic potent and selective blocker of the Gardos channel which is the calcium-activated potassium channel located on the human RBC, inhibiting the efflux of K+ through this channel. Alternative Names: 2,2-bis(4-fluorophenyl)-2-phenylacetamide; bis(4-fluorophenyl)phenylacetamide; ICA 17043; ICA-17043; ICA17043. CAS No. 289656-45-7. Molecular formula: C20H15F2NO. Mole weight: 323.34. | |
| Senna Leaf Extract | Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides. Alternative Names: Senna, Cassia obovata, ext.; Senna extract; Folium Sennae Extract. Grades: 20% (Sennoside A and B). CAS No. 85085-71-8. | |
| Sennoside | Sennoside is an anthraquinone derivative found in senna leaves. Sennoside is used as a laxative in the treatment of constipation. Studies have suggested that the use of Sennoside may be associated with genotoxicity and carcinogenicity, but there is currently no conclusive evidence to support this. Alternative Names: [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-; 5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-bianthracene]-2,2'-dicarboxylic acid; Sennoside (Mixture of A and B). CAS No. 517-43-1. Molecular formula: C42H38O20. Mole weight: 862.74. | |
| Seocalcitol | Seocalcitol is a synthetic vitamin D analog which is 50-200 times more potent than calcitriol at inhibiting cell proliferation and differentiation. It has been shown to promote tumor regression in vitro by inducing apoptosis. Alternative Names: EB-1089; EB1089; (1R,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1-((R,3E,5E)-7-Ethyl-7-hydroxynona-3,5-dien-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-Ethyl-6-hydroxy-1-methyl-2,4-octadien-1-yl]-octahydro-7α-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol. Grades: 95% by HPLC. CAS No. 134404-52-7. Molecular formula: C30H46O3. Mole weight: 454.68. | |
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